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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for FOXQ1

Z-value: 2.48

Motif logo

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Transcription factors associated with FOXQ1

Gene Symbol Gene ID Gene Info
FOXQ1
ENSG00000164379.4 forkhead box Q1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr6_1314130_1314378FOXQ115790.4868530.608.5e-02Click!
chr6_1314412_1314630FOXQ118460.4400530.462.1e-01Click!
chr6_1312231_1312382FOXQ13690.9094540.422.6e-01Click!
chr6_1336097_1336248FOXQ1234970.2031490.304.3e-01Click!
chr6_1314742_1314893FOXQ121420.4015610.294.4e-01Click!

Activity of the FOXQ1 motif across conditions

Conditions sorted by the z-value of the FOXQ1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_120168709_120169860 0.87 FSTL1
 follistatin-like 1
 554
 0.84
chr8_80268388_80268539 0.84 STMN2
 stathmin-like 2
 254586
 0.02
chr9_117879769_117880175 0.82 TNC
 tenascin C
 506
 0.85
chr2_199271076_199271227 0.80 ENSG00000252511
 .
 160302
 0.04
chr5_78985270_78986298 0.72 CMYA5
 cardiomyopathy associated 5
 84
 0.98
chr8_41165480_41165725 0.70 SFRP1
 secreted frizzled-related protein 1
 1093
 0.49
chr3_144899701_144899852 0.67 RP11-274H2.5
879690
 0.0
chr4_119310991_119311142 0.67 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
 36908
 0.2
chr2_164588659_164588810 0.66 FIGN
 fidgetin
 3783
 0.39
chr17_57704803_57704954 0.66 CLTC
 clathrin, heavy chain (Hc)
 7585
 0.21
chr12_88812633_88812784 0.64 ENSG00000199245
 .
 11511
 0.3
chr7_134464463_134465343 0.64 CALD1
 caldesmon 1
 474
 0.89
chr2_217557124_217557955 0.62 AC007563.5
1648
 0.3
chr4_55095719_55096018 0.61 PDGFRA
 platelet-derived growth factor receptor, alpha polypeptide
 142
 0.98
chr12_80309876_80310027 0.60 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 2260
 0.31
chr1_78961164_78961362 0.60 PTGFR
 prostaglandin F receptor (FP)
 4506
 0.32
chr6_19838575_19839711 0.59 RP1-167F1.2
168
 0.95
chr1_59479541_59479891 0.59 JUN
 jun proto-oncogene
 229931
 0.02
chr3_112798260_112798787 0.58 ENSG00000238593
 .
 12849
 0.18
chr1_59950056_59950207 0.55 FGGY
 FGGY carbohydrate kinase domain containing
 69459
 0.14
chr16_65152808_65153250 0.54 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 2804
 0.44
chr4_71570546_71572213 0.54 RUFY3
 RUN and FYVE domain containing 3
 861
 0.36
chr2_55239455_55239731 0.53 RTN4
 reticulon 4
 2008
 0.3
chr12_7037386_7038830 0.53 ATN1
 atrophin 1
 632
 0.41
chr13_97927308_97927620 0.53 MBNL2
 muscleblind-like splicing regulator 2
 994
 0.69
chr9_21557241_21557437 0.53 MIR31HG
 MIR31 host gene (non-protein coding)
 2329
 0.28
chr18_26719252_26719403 0.52 ENSG00000265730
 .
 43684
 0.17
chr11_76621964_76622115 0.51 ENSG00000212030
 .
 32763
 0.15
chr4_138354057_138354215 0.50 PCDH18
 protocadherin 18
 99429
 0.09
chr1_93342801_93342952 0.50 ENSG00000207022
 .
 31260
 0.1
chr8_100511223_100511429 0.49 VPS13B
 vacuolar protein sorting 13 homolog B (yeast)
 21801
 0.16
chr3_149105144_149105295 0.48 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 9213
 0.18
chr7_94045972_94046123 0.48 COL1A2
 collagen, type I, alpha 2
 22174
 0.23
chr12_66122461_66123138 0.48 HMGA2
 high mobility group AT-hook 2
 95112
 0.08
chr3_110798695_110798846 0.48 PVRL3
 poliovirus receptor-related 3
 5719
 0.26
chr3_9464698_9464903 0.48 ENSG00000266001
 .
 3234
 0.2
chr17_9176142_9176293 0.48 RP11-85B7.4
10274
 0.26
chr2_28939308_28939670 0.48 AC097724.3
19486
 0.15
chr4_162635795_162635946 0.48 RP11-497K21.1
308015
 0.01
chr7_116164164_116164509 0.47 CAV1
 caveolin 1, caveolae protein, 22kDa
 503
 0.76
chr12_91570174_91570436 0.47 DCN
 decorin
 2024
 0.44
chr20_53478329_53478480 0.46 ENSG00000252089
 .
 2053
 0.5
chr10_4285552_4285907 0.46 ENSG00000207124
 .
 271415
 0.02
chr2_73021104_73021255 0.46 EXOC6B
 exocyst complex component 6B
 31991
 0.17
chr13_37934950_37935173 0.46 ENSG00000202395
 .
 194266
 0.03
chr12_10869610_10869831 0.45 YBX3
 Y box binding protein 3
 6186
 0.19
chr20_3787781_3788040 0.45 CDC25B
 cell division cycle 25B
 10832
 0.11
chr2_133998643_133998815 0.45 AC010890.1
23811
 0.24
chr11_132813237_132813595 0.45 OPCML
 opioid binding protein/cell adhesion molecule-like
 150
 0.98
chr1_70916763_70916914 0.45 CTH
 cystathionase (cystathionine gamma-lyase)
 39772
 0.17
chr16_53779314_53779624 0.45 FTO
 fat mass and obesity associated
 41375
 0.17
chr12_91575790_91576058 0.45 DCN
 decorin
 505
 0.87
chr4_71479096_71479386 0.45 ENAM
 enamelin
 15220
 0.15
chr12_59312115_59312531 0.45 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 1004
 0.56
chr5_88168642_88169029 0.45 MEF2C
 myocyte enhancer factor 2C
 4959
 0.27
chr3_578313_578483 0.45 CHL1
 cell adhesion molecule L1-like
 147270
 0.05
chr16_67197260_67198336 0.45 HSF4
 heat shock transcription factor 4
 510
 0.52
chr9_35945444_35945832 0.44 OR2S2
 olfactory receptor, family 2, subfamily S, member 2
 12513
 0.14
chr7_115318179_115318344 0.44 ENSG00000202377
 .
 96765
 0.09
chr2_151260036_151260226 0.44 RND3
 Rho family GTPase 3
 81765
 0.12
chr2_223573663_223573851 0.44 ENSG00000238852
 .
 11038
 0.21
chr9_96819103_96819334 0.44 PTPDC1
 protein tyrosine phosphatase domain containing 1
 26142
 0.21
chr16_79626813_79627023 0.43 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
 6881
 0.31
chr10_13931045_13931263 0.43 FRMD4A
 FERM domain containing 4A
 30242
 0.2
chr21_22756152_22756303 0.43 ENSG00000221210
 .
 13919
 0.31
chr7_83817578_83817729 0.43 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 6564
 0.35
chr7_7739484_7739635 0.43 RPA3
 replication protein A3, 14kDa
 18679
 0.24
chr15_43653095_43653309 0.43 ZSCAN29
 zinc finger and SCAN domain containing 29
 8672
 0.11
chr7_19154054_19154205 0.43 AC003986.6
2032
 0.25
chr18_51780819_51781029 0.43 POLI
 polymerase (DNA directed) iota
 14850
 0.19
chr15_33179287_33179438 0.43 FMN1
 formin 1
 1093
 0.55
chr5_72594430_72594934 0.43 TMEM174
 transmembrane protein 174
 125660
 0.05
chr6_119451056_119451214 0.42 FAM184A
 family with sequence similarity 184, member A
 19217
 0.23
chr2_190276875_190277026 0.42 WDR75
 WD repeat domain 75
 29209
 0.22
chr12_13351879_13352395 0.42 EMP1
 epithelial membrane protein 1
 2417
 0.37
chr3_132356756_132356921 0.42 UBA5
 ubiquitin-like modifier activating enzyme 5
 16452
 0.17
chrX_46442135_46442322 0.42 CHST7
 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
 9009
 0.23
chr5_82847726_82847877 0.42 VCAN-AS1
 VCAN antisense RNA 1
 10332
 0.27
chr14_33277835_33277986 0.42 AKAP6
 A kinase (PRKA) anchor protein 6
 72853
 0.13
chr19_37209583_37209835 0.42 ZNF567
 zinc finger protein 567
 6367
 0.17
chr6_4320927_4321159 0.42 ENSG00000201185
 .
 107154
 0.07
chr1_216018435_216018636 0.42 RP5-1111A8.3
41389
 0.22
chr4_81195528_81195918 0.42 FGF5
 fibroblast growth factor 5
 7930
 0.26
chr6_102179072_102179257 0.42 GRIK2
 glutamate receptor, ionotropic, kainate 2
 54520
 0.19
chr18_46620789_46620940 0.42 DYM
 dymeclin
 2999
 0.26
chr19_460012_460518 0.42 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 731
 0.5
chr2_38981206_38981357 0.42 GEMIN6
 gem (nuclear organelle) associated protein 6
 2605
 0.23
chr4_153270968_153271263 0.42 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
 1157
 0.54
chr8_77343383_77343577 0.42 RP11-115I9.1
148100
 0.04
chr13_52164375_52164526 0.41 ENSG00000206920
 .
 3782
 0.16
chr4_166793911_166794064 0.41 TLL1
 tolloid-like 1
 423
 0.91
chr12_12972772_12973017 0.41 DDX47
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
 6600
 0.18
chr3_149371362_149371801 0.41 WWTR1-AS1
 WWTR1 antisense RNA 1
 3226
 0.2
chr10_10867017_10867168 0.41 CELF2
 CUGBP, Elav-like family member 2
 180167
 0.03
chr1_179096167_179096689 0.41 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
 15751
 0.19
chr1_214161782_214162525 0.41 PROX1
 prospero homeobox 1
 293
 0.86
chr7_42273288_42273439 0.41 GLI3
 GLI family zinc finger 3
 3249
 0.41
chr2_203888006_203888157 0.41 NBEAL1
 neurobeachin-like 1
 8479
 0.23
chr12_80903923_80904074 0.41 PTPRQ
 protein tyrosine phosphatase, receptor type, Q
 65872
 0.12
chr10_112113428_112113665 0.40 SMNDC1
 survival motor neuron domain containing 1
 48837
 0.14
chr16_54967868_54968019 0.40 IRX5
 iroquois homeobox 5
 1959
 0.5
chr5_80801619_80801770 0.40 SSBP2
 single-stranded DNA binding protein 2
 7842
 0.3
chr1_224805949_224806359 0.40 CNIH3
 cornichon family AMPA receptor auxiliary protein 3
 2159
 0.29
chr17_2309940_2310157 0.40 MNT
 MAX network transcriptional repressor
 5636
 0.12
chr6_125698814_125699135 0.40 RP11-735G4.1
3504
 0.35
chr4_87517094_87517245 0.40 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
 323
 0.88
chr4_66185713_66185864 0.40 EPHA5
 EPH receptor A5
 349865
 0.01
chr8_116594269_116594420 0.40 TRPS1
 trichorhinophalangeal syndrome I
 37953
 0.21
chr6_42789344_42789495 0.40 GLTSCR1L
 GLTSCR1-like
 625
 0.7
chr3_105584255_105584406 0.40 CBLB
 Cbl proto-oncogene B, E3 ubiquitin protein ligase
 3557
 0.4
chr12_86229562_86230264 0.40 RASSF9
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
 435
 0.89
chr10_54077811_54078125 0.40 DKK1
 dickkopf WNT signaling pathway inhibitor 1
 3912
 0.28
chr14_95949817_95950024 0.39 SYNE3
 spectrin repeat containing, nuclear envelope family member 3
 7747
 0.18
chr6_112121319_112121470 0.39 FYN
 FYN oncogene related to SRC, FGR, YES
 1768
 0.49
chr22_46479348_46479691 0.39 FLJ27365
 hsa-mir-4763
 2364
 0.16
chr8_54817773_54817967 0.39 ENSG00000200528
 .
 9409
 0.19
chr4_77905705_77905940 0.39 SEPT11
 septin 11
 355
 0.91
chr5_76134459_76134610 0.39 ENSG00000264391
 .
 1514
 0.35
chr10_32096471_32096622 0.39 ARHGAP12
 Rho GTPase activating protein 12
 46562
 0.16
chr5_20013347_20013498 0.39 CDH18
 cadherin 18, type 2
 25083
 0.28
chr10_4284322_4284712 0.38 ENSG00000207124
 .
 272627
 0.02
chr1_66737250_66737924 0.38 PDE4B
 phosphodiesterase 4B, cAMP-specific
 14257
 0.29
chr6_126074032_126074183 0.38 HEY2
 hes-related family bHLH transcription factor with YRPW motif 2
 3381
 0.22
chr9_22117681_22117895 0.38 CDKN2B-AS1
 CDKN2B antisense RNA 1
 4111
 0.31
chr8_17657715_17658703 0.38 MTUS1
 microtubule associated tumor suppressor 1
 32
 0.93
chr8_14823396_14823547 0.38 CTD-2023J5.1
86143
 0.1
chr4_188523742_188524026 0.38 ZFP42
 ZFP42 zinc finger protein
 393041
 0.01
chr21_17795103_17795329 0.38 ENSG00000207638
 .
 116193
 0.06
chr6_139433928_139434079 0.38 HECA
 headcase homolog (Drosophila)
 22246
 0.23
chr18_22831289_22831440 0.38 ZNF521
 zinc finger protein 521
 19870
 0.26
chr10_95230941_95231222 0.38 MYOF
 myoferlin
 10870
 0.19
chr1_109420809_109421004 0.38 GPSM2
 G-protein signaling modulator 2
 876
 0.56
chr21_23436399_23436550 0.38 ENSG00000202339
 .
 141037
 0.05
chr3_55520023_55520469 0.38 WNT5A
 wingless-type MMTV integration site family, member 5A
 1085
 0.48
chr12_32261770_32262117 0.38 RP11-843B15.2
1481
 0.38
chr5_75545047_75545198 0.38 RP11-466P24.6
62165
 0.14
chr7_87257054_87258255 0.38 RUNDC3B
 RUN domain containing 3B
 75
 0.97
chr6_49521544_49521695 0.37 C6orf141
 chromosome 6 open reading frame 141
 3506
 0.27
chr1_163173209_163173360 0.37 RGS5
 regulator of G-protein signaling 5
 381
 0.89
chr2_119605581_119605886 0.37 EN1
 engrailed homeobox 1
 479
 0.88
chr5_82442000_82442151 0.37 XRCC4
 X-ray repair complementing defective repair in Chinese hamster cells 4
 68663
 0.11
chr4_139840588_139840739 0.37 RP11-371F15.3
18472
 0.22
chr1_172110530_172111247 0.37 ENSG00000207949
 .
 2841
 0.22
chr17_11041276_11041427 0.37 ENSG00000243346
 .
 19421
 0.24
chr7_84412645_84412796 0.37 ENSG00000265050
 .
 117396
 0.07
chr2_145868497_145868648 0.37 ENSG00000253036
 .
 224066
 0.02
chr2_40049399_40049550 0.37 SLC8A1-AS1
 SLC8A1 antisense RNA 1
 35881
 0.19
chr18_9180940_9181091 0.37 ANKRD12
 ankyrin repeat domain 12
 1369
 0.41
chr4_27007063_27007214 0.37 STIM2
 stromal interaction molecule 2
 2516
 0.43
chr6_84139529_84139855 0.37 ME1
 malic enzyme 1, NADP(+)-dependent, cytosolic
 1072
 0.62
chr13_33858654_33859881 0.37 STARD13
 StAR-related lipid transfer (START) domain containing 13
 625
 0.76
chr12_20700564_20700849 0.37 SLCO1C1
 solute carrier organic anion transporter family, member 1C1
 147583
 0.04
chr5_59095178_59095364 0.37 PDE4D
 phosphodiesterase 4D, cAMP-specific
 30800
 0.24
chr12_10874089_10875353 0.37 YBX3
 Y box binding protein 3
 1185
 0.46
chr6_112336237_112336388 0.37 WISP3
 WNT1 inducible signaling pathway protein 3
 38963
 0.16
chr3_153011447_153011598 0.37 ENSG00000265813
 .
 93716
 0.08
chr2_164586863_164587014 0.36 FIGN
 fidgetin
 5579
 0.36
chr9_109049783_109049934 0.36 ENSG00000200131
 .
 392400
 0.01
chr12_107352268_107352490 0.36 C12orf23
 chromosome 12 open reading frame 23
 1816
 0.3
chr15_69710069_69710220 0.36 RP11-253M7.1
2776
 0.17
chr15_60684685_60685107 0.36 ANXA2
 annexin A2
 1400
 0.54
chr17_65208623_65208774 0.36 RP11-401F2.4
11721
 0.16
chr1_216705124_216705304 0.36 USH2A
 Usher syndrome 2A (autosomal recessive, mild)
 108476
 0.08
chr19_10231444_10231730 0.36 EIF3G
 eukaryotic translation initiation factor 3, subunit G
 1009
 0.29
chr10_94958545_94959442 0.36 CYP26A1
 cytochrome P450, family 26, subfamily A, polypeptide 1
 125346
 0.05
chr13_35735241_35735392 0.36 NBEA
 neurobeachin
 218519
 0.02
chr7_3454977_3455128 0.36 ENSG00000211544
 .
 3647
 0.35
chr13_35962874_35963128 0.36 MAB21L1
 mab-21-like 1 (C. elegans)
 87831
 0.09
chr5_54456456_54456818 0.36 GPX8
 glutathione peroxidase 8 (putative)
 639
 0.58
chr15_60681239_60681623 0.36 ANXA2
 annexin A2
 1895
 0.45
chr1_104865841_104865992 0.36 AMY1C
 amylase, alpha 1C (salivary)
 572888
 0.0
chr1_246750885_246751091 0.36 RP11-439E19.1
18187
 0.16
chr14_36786542_36786693 0.36 MBIP
 MAP3K12 binding inhibitory protein 1
 2459
 0.33
chr6_72060262_72060413 0.36 RP11-154D6.1
22406
 0.17
chr3_156804877_156805028 0.36 ENSG00000201778
 .
 66385
 0.09
chr13_31482253_31482459 0.36 MEDAG
 mesenteric estrogen-dependent adipogenesis
 1513
 0.41
chr4_77931733_77931884 0.36 SEPT11
 septin 11
 9877
 0.24
chr4_175075425_175075781 0.36 FBXO8
 F-box protein 8
 129211
 0.05
chr1_115782889_115783040 0.36 RP4-663N10.1
42691
 0.18
chr10_34999688_34999839 0.36 PARD3
 par-3 family cell polarity regulator
 104486
 0.07
chr10_105654143_105654294 0.36 RP11-541N10.3
14699
 0.16
chr7_7611886_7612037 0.36 MIOS
 missing oocyte, meiosis regulator, homolog (Drosophila)
 4847
 0.26
chr21_32007327_32007478 0.35 KRTAP20-2
 keratin associated protein 20-2
 153
 0.9
chr4_30727648_30727863 0.35 PCDH7
 protocadherin 7
 3778
 0.36
chr10_94725160_94725374 0.35 EXOC6
 exocyst complex component 6
 31964
 0.2
chr6_56239740_56239891 0.35 COL21A1
 collagen, type XXI, alpha 1
 19077
 0.21
chr6_16737906_16738057 0.35 RP1-151F17.1
23388
 0.22
chr18_6434497_6434648 0.35 ENSG00000265628
 .
 2765
 0.26
chr7_87671450_87671601 0.35 ADAM22
 ADAM metallopeptidase domain 22
 107454
 0.07
chr17_17974625_17974776 0.35 DRG2
 developmentally regulated GTP binding protein 2
 16500
 0.12
chr7_113722711_113723554 0.35 FOXP2
 forkhead box P2
 3483
 0.3
chr2_158712083_158712248 0.35 ENSG00000215934
 .
 307
 0.9
chr16_50374512_50374663 0.35 ENSG00000238544
 .
 11616
 0.17
chr7_33935195_33935371 0.35 BMPER
 BMP binding endothelial regulator
 9240
 0.31
chr16_89497480_89497631 0.35 RP1-168P16.1
8921
 0.13
chr15_57986391_57986542 0.35 POLR2M
 polymerase (RNA) II (DNA directed) polypeptide M
 12361
 0.26
chr4_177824622_177824937 0.35 VEGFC
 vascular endothelial growth factor C
 110898
 0.07
chr3_81807400_81807551 0.35 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 3837
 0.39
chr4_18595427_18595619 0.35 LCORL
 ligand dependent nuclear receptor corepressor-like
 572024
 0.0
chr12_19358848_19358999 0.35 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 664
 0.75

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXQ1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 0.9 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.3 1.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.5 GO:0031223 auditory behavior(GO:0031223)
0.2 0.6 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.2 0.2 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.8 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.6 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.2 1.0 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.2 0.7 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.5 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.4 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.4 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.4 GO:0060242 contact inhibition(GO:0060242)
0.1 0.5 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.5 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.7 GO:0001553 luteinization(GO:0001553)
0.1 0.5 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.1 GO:0006949 syncytium formation(GO:0006949)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.3 GO:0060900 embryonic camera-type eye formation(GO:0060900)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.4 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.4 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.2 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.1 0.1 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.2 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.4 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.3 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1 0.1 GO:0060841 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.1 0.2 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 1.0 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 0.4 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.1 GO:0061364 Roundabout signaling pathway(GO:0035385) apoptotic process involved in luteolysis(GO:0061364)
0.1 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.2 GO:0007412 axon target recognition(GO:0007412)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 1.1 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.4 GO:1901862 negative regulation of muscle tissue development(GO:1901862)
0.1 0.1 GO:0060685 regulation of prostatic bud formation(GO:0060685)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.2 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.1 GO:0050955 thermoception(GO:0050955)
0.1 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.1 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.3 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.1 GO:0042637 catagen(GO:0042637)
0.1 0.2 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0002076 osteoblast development(GO:0002076)
0.1 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 1.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.1 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.1 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.1 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0042023 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.3 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.1 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.4 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.3 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.4 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.5 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.3 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.7 GO:0007492 endoderm development(GO:0007492)
0.0 0.5 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.3 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0060571 morphogenesis of an epithelial fold(GO:0060571)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0098743 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0 0.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 3.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0085029 extracellular matrix assembly(GO:0085029)
0.0 1.1 GO:0071773 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.1 GO:0021871 forebrain regionalization(GO:0021871)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0031128 developmental induction(GO:0031128)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.2 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.0 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0036303 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0 0.1 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0031034 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0044851 hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.0 0.0 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0031645 negative regulation of neurological system process(GO:0031645)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.0 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0043049 otic placode formation(GO:0043049)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0098773 hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.0 0.0 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:0070193 synaptonemal complex organization(GO:0070193)
0.0 0.3 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539)
0.0 0.2 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.0 GO:2000008 regulation of protein localization to cell surface(GO:2000008)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.0 GO:0055009 atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
0.0 0.1 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0010561 negative regulation of glycoprotein biosynthetic process(GO:0010561)
0.0 0.1 GO:0014033 neural crest cell differentiation(GO:0014033)
0.0 0.0 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.0 GO:0015816 glycine transport(GO:0015816)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0042596 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209) fear response(GO:0042596)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043) negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 0.8 GO:0071437 invadopodium(GO:0071437)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 1.2 GO:0005811 lipid particle(GO:0005811)
0.1 0.5 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.2 GO:0032059 bleb(GO:0032059)
0.1 0.2 GO:0045298 tubulin complex(GO:0045298)
0.1 0.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.3 GO:0030673 axolemma(GO:0030673)
0.1 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 2.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 4.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 2.0 GO:0030016 myofibril(GO:0030016)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.2 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.3 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 1.0 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.8 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.6 GO:0045545 syndecan binding(GO:0045545)
0.2 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.2 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.5 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.5 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 1.0 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.5 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.5 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.5 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0031545 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.0 GO:0015216 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.0 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.0 GO:0099589 G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.0 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.1 0.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.8 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.1 REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR Genes involved in Downstream signaling of activated FGFR
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.1 REACTOME PHOSPHOLIPASE C MEDIATED CASCADE Genes involved in Phospholipase C-mediated cascade
0.1 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.0 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.5 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.4 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation