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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for GATA5

Z-value: 3.33

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Transcription factors associated with GATA5

Gene Symbol	Gene ID	Gene Info
GATA5 Ensembl NCBI GeneCards UniProt	ENSG00000130700.6	GATA binding protein 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr20_61057984_61058135	GATA5	7033	0.173430	-0.44	2.4e-01	Click!
chr20_61050571_61050722	GATA5	380	0.842769	0.36	3.4e-01	Click!
chr20_61057129_61057280	GATA5	6178	0.177363	0.31	4.1e-01	Click!
chr20_61049732_61049883	GATA5	1219	0.432570	-0.30	4.3e-01	Click!
chr20_61064540_61064691	GATA5	13589	0.158571	0.24	5.4e-01	Click!

Activity of the GATA5 motif across conditions

Conditions sorted by the z-value of the GATA5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr20_14314803_14314963	1.27	FLRT3	fibronectin leucine rich transmembrane protein 3	3371	0.3
chr12_14546468_14546619	1.24	ATF7IP	activating transcription factor 7 interacting protein	1254	0.55
chr18_2606249_2606519	1.00	NDC80	NDC80 kinetochore complex component	4396	0.17
chr3_188572304_188572605	0.87	TPRG1	tumor protein p63 regulated 1	92549	0.09
chr14_22593025_22593176	0.83	ENSG00000238634	.	17787	0.27
chr18_33057581_33058355	0.82	INO80C	INO80 complex subunit C	9466	0.21
chr11_129118842_129119000	0.81	ARHGAP32	Rho GTPase activating protein 32	30298	0.2
chr2_203881741_203882170	0.81	NBEAL1	neurobeachin-like 1	2353	0.35
chr3_71678048_71678199	0.80	FOXP1	forkhead box P1	44983	0.15
chr6_159235914_159236507	0.76	EZR-AS1	EZR antisense RNA 1	2833	0.23
chr5_124827830_124828314	0.75	ENSG00000222107	.	141248	0.05
chr4_114880272_114880510	0.75	RP11-26P13.2		15979	0.24
chr1_82271501_82271652	0.75	LPHN2	latrophilin 2	5494	0.35
chr13_67732158_67732309	0.74	PCDH9	protocadherin 9	70339	0.13
chr2_177356582_177356733	0.74	ENSG00000221304	.	108353	0.06
chr4_183174796_183174947	0.74	TENM3	teneurin transmembrane protein 3	10289	0.27
chr6_134581827_134581978	0.73	SGK1	serum/glucocorticoid regulated kinase 1	1295	0.43
chr11_35179065_35179361	0.73	CD44	CD44 molecule (Indian blood group)	18360	0.15
chr7_94282819_94282979	0.71	SGCE	sarcoglycan, epsilon	2511	0.28
chr4_109086470_109087224	0.70	LEF1	lymphoid enhancer-binding factor 1	610	0.72
chr17_64327814_64327965	0.69	PRKCA	protein kinase C, alpha	28945	0.16
chr5_85693756_85693907	0.69	NBPF22P	neuroblastoma breakpoint family, member 22, pseudogene	115247	0.07
chr5_73837343_73837494	0.69	HEXB	hexosaminidase B (beta polypeptide)	98430	0.07
chr18_57505043_57505194	0.68	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	62062	0.12
chr14_99658183_99658959	0.68	AL162151.4		33818	0.19
chr15_87678295_87678446	0.68	RP11-133L19.1		146713	0.05
chr1_158903283_158903483	0.68	PYHIN1	pyrin and HIN domain family, member 1	2025	0.36
chr2_3625481_3625934	0.67	ENSG00000252531	.	2453	0.16
chrX_129978119_129978270	0.65	ENOX2	ecto-NOX disulfide-thiol exchanger 2	58984	0.16
chr14_22989269_22989534	0.63	TRAJ15	T cell receptor alpha joining 15	9179	0.11
chr18_26663361_26663762	0.63	ENSG00000265730	.	12082	0.25
chr7_104907675_104908170	0.63	SRPK2	SRSF protein kinase 2	1540	0.45
chrX_86773122_86773424	0.63	KLHL4	kelch-like family member 4	456	0.88
chrX_78343760_78343985	0.62	GPR174	G protein-coupled receptor 174	82597	0.11
chr1_200698832_200698983	0.62	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2	9779	0.25
chr12_52844894_52845045	0.62	KRT6B	keratin 6B	941	0.39
chr3_188840217_188840368	0.61	TPRG1	tumor protein p63 regulated 1	22382	0.27
chr3_20084808_20085457	0.61	KAT2B	K(lysine) acetyltransferase 2B	3617	0.24
chr9_14308597_14308748	0.61	NFIB	nuclear factor I/B	660	0.78
chr1_93816589_93816740	0.61	ENSG00000223745	.	5082	0.2
chr13_68238536_68238687	0.61	PCDH9	protocadherin 9	434143	0.01
chr12_47611625_47611801	0.61	PCED1B	PC-esterase domain containing 1B	1332	0.49
chr9_33162104_33162255	0.60	RP11-326F20.5		4794	0.16
chr3_105787909_105788060	0.60	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	199588	0.03
chr2_161055572_161055723	0.60	ITGB6	integrin, beta 6	1116	0.65
chr10_23658089_23658240	0.59	ENSG00000264574	.	24170	0.14
chr2_213999106_213999257	0.59	IKZF2	IKAROS family zinc finger 2 (Helios)	14172	0.29
chr6_49231632_49231783	0.58	ENSG00000252457	.	80814	0.11
chr18_63233244_63233395	0.58	CDH7	cadherin 7, type 2	184169	0.03
chr16_78156962_78157154	0.58	WWOX	WW domain containing oxidoreductase	23467	0.22
chr1_182994808_182995119	0.58	LAMC1	laminin, gamma 1 (formerly LAMB2)	2368	0.3
chr5_84331121_84331272	0.58	ENSG00000215953	.	492756	0.01
chr5_39198391_39198564	0.57	FYB	FYN binding protein	4652	0.32
chr11_46581548_46581763	0.57	AMBRA1	autophagy/beclin-1 regulator 1	31259	0.15
chr18_59948340_59948666	0.57	KIAA1468	KIAA1468	19659	0.14
chr16_53114124_53114275	0.57	CHD9	chromodomain helicase DNA binding protein 9	18873	0.21
chr5_45697193_45697344	0.57	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	1015	0.72
chr5_35857058_35857643	0.56	IL7R	interleukin 7 receptor	356	0.89
chr8_19905553_19905704	0.56	AC100802.3		31188	0.21
chr14_22572085_22572236	0.56	ENSG00000238634	.	38727	0.2
chrX_32720099_32720250	0.56	DMD-AS3	DMD antisense RNA 3	52883	0.15
chr2_168406531_168406682	0.56	ENSG00000238357	.	81445	0.12
chr10_32229231_32229382	0.56	ARHGAP12	Rho GTPase activating protein 12	11564	0.24
chr6_53500075_53500226	0.56	RP11-345L23.1		6972	0.19
chrX_128457110_128457261	0.55	ENSG00000201518	.	113439	0.07
chr1_185779108_185779259	0.55	HMCN1	hemicentin 1	75500	0.12
chr14_81939027_81939178	0.55	STON2	stonin 2	36293	0.21
chr2_197788792_197788943	0.54	PGAP1	post-GPI attachment to proteins 1	2587	0.36
chr3_45985242_45985393	0.54	CXCR6	chemokine (C-X-C motif) receptor 6	353	0.85
chr3_189743062_189743213	0.54	ENSG00000265045	.	88586	0.08
chr14_22948566_22948717	0.54	ENSG00000251002	.	1637	0.2
chr2_11197283_11197434	0.54	C2orf50	chromosome 2 open reading frame 50	75821	0.1
chr4_77923298_77923449	0.54	SEPT11	septin 11	6338	0.26
chr14_99731258_99732023	0.53	AL109767.1		2355	0.32
chr3_172536308_172536599	0.53	ECT2	epithelial cell transforming sequence 2 oncogene	15972	0.18
chr22_34207449_34207600	0.53	LARGE	like-glycosyltransferase	50088	0.14
chr3_81322506_81322657	0.53	ENSG00000222389	.	236046	0.02
chr4_36713843_36713994	0.53	RP11-431M7.2		319886	0.01
chr6_12280277_12280428	0.52	EDN1	endothelin 1	10244	0.3
chr9_36603313_36603464	0.52	MELK	maternal embryonic leucine zipper kinase	30480	0.23
chr3_143568997_143569148	0.52	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	1699	0.53
chr12_10328719_10328870	0.52	TMEM52B	transmembrane protein 52B	2818	0.18
chr8_60885354_60885505	0.52	CA8	carbonic anhydrase VIII	308542	0.01
chr2_30476045_30476196	0.52	LBH	limb bud and heart development	21074	0.22
chrX_107640889_107641040	0.52	COL4A6	collagen, type IV, alpha 6	40592	0.17
chr4_153431926_153432077	0.52	ENSG00000264678	.	21433	0.17
chr9_95165559_95165710	0.51	OGN	osteoglycin	1207	0.46
chr6_10409741_10409958	0.51	TFAP2A-AS1	TFAP2A antisense RNA 1	276	0.67
chr10_13382497_13382864	0.51	SEPHS1	selenophosphate synthetase 1	110	0.97
chr20_11524234_11524385	0.51	ENSG00000222281	.	275430	0.02
chr10_33240556_33240863	0.51	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	3882	0.33
chr2_69662737_69662888	0.51	NFU1	NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)	1737	0.4
chr9_22240911_22241173	0.51	CDKN2B-AS1	CDKN2B antisense RNA 1	127365	0.05
chr5_97126080_97126231	0.51	CTD-2215E18.2		588571	0.0
chr7_109521230_109521381	0.51	AC073326.3		844576	0.0
chr8_115918850_115919001	0.51	TRPS1	trichorhinophalangeal syndrome I	585523	0.0
chr11_58328854_58329005	0.50	LPXN	leupaxin	14405	0.15
chr7_151174329_151174594	0.50	ENSG00000241959	.	12437	0.14
chr1_85528516_85528667	0.50	WDR63	WD repeat domain 63	581	0.76
chr3_145966767_145966918	0.50	PLSCR4	phospholipid scramblase 4	1812	0.47
chr12_71721523_71721674	0.50	LGR5	leucine-rich repeat containing G protein-coupled receptor 5	111952	0.06
chr13_71667523_71667674	0.50	ENSG00000202433	.	634002	0.0
chr1_39742025_39742176	0.50	MACF1	microtubule-actin crosslinking factor 1	7901	0.2
chr14_22971180_22971468	0.50	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	15153	0.1
chr6_87867258_87867409	0.49	ZNF292	zinc finger protein 292	1994	0.3
chr1_36004513_36004681	0.49	KIAA0319L	KIAA0319-like	15991	0.15
chr1_111212431_111212582	0.49	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	5149	0.2
chr8_42034876_42035027	0.49	AP3M2	adaptor-related protein complex 3, mu 2 subunit	10144	0.16
chr11_117151077_117151258	0.49	BACE1	beta-site APP-cleaving enzyme 1	15034	0.13
chr8_94932317_94932517	0.49	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	310	0.9
chr1_225923826_225924038	0.48	RP11-145A3.2		44	0.97
chr7_56261128_56261279	0.48	ENSG00000265887	.	76341	0.07
chr13_87381372_87381523	0.48	ENSG00000266052	.	889548	0.0
chr20_57721382_57721625	0.48	ZNF831	zinc finger protein 831	44572	0.15
chr9_18268349_18268500	0.48	ADAMTSL1	ADAMTS-like 1	205468	0.03
chr7_103577846_103577997	0.48	RELN	reelin	52042	0.18
chr7_120764220_120764371	0.48	ENSG00000212628	.	40428	0.16
chr18_64491554_64491705	0.48	ENSG00000238680	.	121724	0.06
chr6_116718983_116719178	0.48	DSE	dermatan sulfate epimerase	26970	0.15
chr11_20388995_20389167	0.48	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa	3355	0.31
chr18_60825953_60826104	0.48	RP11-299P2.1		7475	0.24
chr7_17055399_17055550	0.48	AGR3	anterior gradient 3	133863	0.05
chr10_113590379_113590912	0.48	GPAM	glycerol-3-phosphate acyltransferase, mitochondrial	352823	0.01
chr2_9781884_9782035	0.47	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta	10816	0.2
chr10_93970997_93971148	0.47	ENSG00000221042	.	7009	0.19
chr12_105619440_105619795	0.47	APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	4021	0.27
chr3_48752945_48753163	0.47	IP6K2	inositol hexakisphosphate kinase 2	92	0.95
chr12_96839645_96840068	0.47	ENSG00000263364	.	2598	0.28
chr4_153270029_153270180	0.46	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	146	0.97
chr5_94551865_94552016	0.46	MCTP1	multiple C2 domains, transmembrane 1	67764	0.13
chr7_6387288_6387439	0.46	FAM220A	family with sequence similarity 220, member A	1026	0.53
chr16_69485221_69485372	0.46	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	26610	0.14
chr11_102176275_102176426	0.46	ENSG00000212466	.	8103	0.18
chr8_16612533_16612758	0.46	ENSG00000264092	.	108360	0.07
chr2_73963170_73963321	0.46	TPRKB	TP53RK binding protein	1268	0.45
chr1_170137734_170137885	0.46	ENSG00000263390	.	17290	0.21
chr16_1466438_1466589	0.46	UNKL	unkempt family zinc finger-like	1761	0.16
chr16_85782638_85782789	0.46	C16orf74	chromosome 16 open reading frame 74	1844	0.22
chr1_51980471_51980722	0.46	RP11-191G24.1		3385	0.2
chr18_63391318_63391469	0.45	CDH7	cadherin 7, type 2	26095	0.27
chr1_39416597_39416748	0.45	ENSG00000207466	.	75	0.96
chr18_22566959_22567110	0.45	ZNF521	zinc finger protein 521	237719	0.02
chr4_95333609_95333990	0.45	PDLIM5	PDZ and LIM domain 5	39238	0.2
chr13_77126631_77126782	0.45	KCTD12	potassium channel tetramerization domain containing 12	333819	0.01
chr6_149081726_149081986	0.45	UST	uronyl-2-sulfotransferase	13392	0.3
chr21_35183695_35183846	0.45	ITSN1	intersectin 1 (SH3 domain protein)	11543	0.23
chr6_81853962_81854113	0.45	RP1-300G12.2		390593	0.01
chr5_106938742_106938893	0.44	EFNA5	ephrin-A5	67511	0.14
chr17_33859992_33860143	0.44	SLFN12L	schlafen family member 12-like	4813	0.13
chr1_174989067_174989218	0.44	ENSG00000206659	.	2574	0.2
chr6_22827851_22828002	0.44	HDGFL1	hepatoma derived growth factor-like 1	258131	0.02
chr4_107417267_107417418	0.44	ENSG00000222333	.	80400	0.11
chr2_113437547_113437698	0.44	SLC20A1	solute carrier family 20 (phosphate transporter), member 1	32343	0.14
chr8_128492794_128493088	0.44	CASC8	cancer susceptibility candidate 8 (non-protein coding)	1443	0.55
chr13_36422905_36423056	0.44	DCLK1	doublecortin-like kinase 1	6799	0.33
chr8_29316973_29317168	0.44	RP4-676L2.1		106383	0.06
chr5_77901409_77901560	0.44	LHFPL2	lipoma HMGIC fusion partner-like 2	43164	0.21
chr15_38558851_38559240	0.44	SPRED1	sprouty-related, EVH1 domain containing 1	13663	0.3
chr4_68593746_68593897	0.44	UBA6-AS1	UBA6 antisense RNA 1 (head to head)	4041	0.2
chr5_162936529_162936895	0.44	MAT2B	methionine adenosyltransferase II, beta	4092	0.2
chr13_48988954_48989249	0.44	LPAR6	lysophosphatidic acid receptor 6	11942	0.27
chr10_130673966_130674117	0.43	MGMT	O-6-methylguanine-DNA methyltransferase	591407	0.0
chr7_25873336_25873487	0.43	ENSG00000199085	.	116195	0.07
chr5_77702587_77702738	0.43	SCAMP1	secretory carrier membrane protein 1	46323	0.16
chr12_1312998_1313266	0.43	ERC1	ELKS/RAB6-interacting/CAST family member 1	176194	0.03
chr12_1224440_1224591	0.43	ERC1	ELKS/RAB6-interacting/CAST family member 1	87577	0.08
chr15_72779845_72780146	0.43	ARIH1	ariadne RBR E3 ubiquitin protein ligase 1	13009	0.2
chr3_189743937_189744088	0.43	ENSG00000265045	.	87711	0.08
chr6_37410160_37410312	0.43	CMTR1	cap methyltransferase 1	9240	0.22
chr14_21565717_21565900	0.43	ZNF219	zinc finger protein 219	991	0.3
chr13_49063882_49064033	0.43	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2	43256	0.17
chr22_47331090_47331241	0.43	ENSG00000221672	.	87362	0.09
chr6_149643931_149644082	0.43	TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	1818	0.37
chr14_74100045_74101313	0.43	RP3-414A15.10		35	0.96
chr2_205921331_205921482	0.43	PARD3B	par-3 family cell polarity regulator beta	510683	0.0
chr13_107070390_107070541	0.42	EFNB2	ephrin-B2	116997	0.07
chr6_112154437_112154588	0.42	FYN	FYN oncogene related to SRC, FGR, YES	11635	0.28
chr4_120584884_120585146	0.42	PDE5A	phosphodiesterase 5A, cGMP-specific	34869	0.21
chr4_169490767_169491028	0.42	PALLD	palladin, cytoskeletal associated protein	58178	0.12
chr3_29377145_29377315	0.42	ENSG00000216169	.	33682	0.18
chr5_148664029_148664180	0.42	AC012613.2		7736	0.13
chr1_167165756_167165907	0.42	RP11-277B15.2		802	0.62
chr3_153850788_153850939	0.42	ARHGEF26	Rho guanine nucleotide exchange factor (GEF) 26	11634	0.22
chr17_46691299_46691963	0.42	HOXB8	homeobox B8	435	0.6
chr2_38826300_38826455	0.42	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	791	0.61
chrX_40028556_40028817	0.42	BCOR	BCL6 corepressor	7887	0.31
chr13_101898505_101898656	0.41	NALCN	sodium leak channel, non-selective	152925	0.04
chr2_157552795_157552946	0.41	AC011308.1		200215	0.03
chr5_67576888_67577103	0.41	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	860	0.74
chr1_198613830_198613981	0.41	PTPRC	protein tyrosine phosphatase, receptor type, C	5613	0.26
chrX_111214548_111214699	0.41	TRPC5OS	TRPC5 opposite strand	89498	0.09
chr8_17611078_17611229	0.41	MTUS1	microtubule associated tumor suppressor 1	2337	0.26
chr3_4783239_4783390	0.41	ENSG00000239126	.	137072	0.05
chr12_27825805_27825956	0.41	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	9677	0.15
chr3_52968929_52969080	0.41	TMEM110	transmembrane protein 110	37392	0.12
chr22_34365006_34365157	0.41	LARGE	like-glycosyltransferase	46252	0.17
chr1_209393485_209393990	0.41	ENSG00000230937	.	211741	0.02
chr2_81994601_81994752	0.41	ENSG00000242118	.	199527	0.03
chr1_111420388_111420605	0.41	CD53	CD53 molecule	4720	0.22
chr7_33946434_33946598	0.41	BMPER	BMP binding endothelial regulator	1371	0.6

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.3	0.6	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.3	1.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2	0.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2	0.6	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.9	GO:0032876	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2	0.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.2	0.7	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.5	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.4	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	0.4	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.3	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.4	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.1	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.3	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.5	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.3	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.2	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.3	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.4	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.7	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.1	0.2	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.1	0.3	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.2	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.1	0.1	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.1	0.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.1	0.2	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1	0.2	GO:0072081	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.4	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.1	0.3	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.2	GO:0070170	regulation of tooth mineralization(GO:0070170)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.2	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	0.2	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.3	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.5	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.4	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.7	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.4	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.1	0.3	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.5	GO:0045176	apical protein localization(GO:0045176)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1	0.5	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.1	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.1	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.1	0.1	GO:0072217	negative regulation of metanephros development(GO:0072217)
0.1	0.2	GO:0015853	adenine transport(GO:0015853)
0.1	0.2	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.2	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.2	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.1	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.1	0.1	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.6	GO:0035329	hippo signaling(GO:0035329)
0.1	0.2	GO:0002857	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.3	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.6	GO:0021516	dorsal spinal cord development(GO:0021516)
0.1	0.2	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.2	GO:0001757	somite specification(GO:0001757)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.6	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0072224	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.2	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.7	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.4	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.5	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.0	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0010159	specification of organ position(GO:0010159)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.2	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.2	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.3	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.1	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0060117	auditory receptor cell development(GO:0060117)
0.0	0.0	GO:0021602	cranial nerve morphogenesis(GO:0021602)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.3	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.3	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.3	GO:0015791	polyol transport(GO:0015791)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.3	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.0	0.0	GO:0048570	notochord morphogenesis(GO:0048570)
0.0	0.3	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.0	GO:0046622	positive regulation of organ growth(GO:0046622)
0.0	0.1	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.2	GO:0060421	positive regulation of heart growth(GO:0060421)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.2	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.1	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0032097	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.1	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.3	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0	0.6	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.1	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0006273	lagging strand elongation(GO:0006273)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.3	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.2	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.2	GO:0031112	positive regulation of microtubule polymerization or depolymerization(GO:0031112)
0.0	0.1	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.2	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.0	GO:0002068	glandular epithelial cell development(GO:0002068)
0.0	0.1	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0045112	integrin biosynthetic process(GO:0045112)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.0	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0031113	regulation of microtubule polymerization(GO:0031113)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0032933	SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0014889	muscle atrophy(GO:0014889)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.2	GO:0007566	embryo implantation(GO:0007566)
0.0	0.2	GO:0008595	blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.3	GO:0007398	ectoderm development(GO:0007398)
0.0	0.0	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.3	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:1903306	negative regulation of regulated secretory pathway(GO:1903306)
0.0	0.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.0	GO:0060179	male mating behavior(GO:0060179)
0.0	0.0	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.3	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0051294	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0055022	negative regulation of organ growth(GO:0046621) negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.2	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0045954	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.1	GO:0032375	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0	0.1	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0006287	base-excision repair, gap-filling(GO:0006287)
0.0	0.0	GO:0048859	formation of anatomical boundary(GO:0048859)
0.0	0.1	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.1	GO:0060287	epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0	0.1	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0048820	anagen(GO:0042640) hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.0	0.1	GO:0000239	pachytene(GO:0000239)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.1	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.2	GO:0044409	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.0	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0051154	negative regulation of striated muscle cell differentiation(GO:0051154)
0.0	0.1	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0048739	myosin filament organization(GO:0031033) cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0008218	bioluminescence(GO:0008218)
0.0	0.1	GO:0071027	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.0	GO:0090312	regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0	0.2	GO:0003156	regulation of organ formation(GO:0003156)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0021680	cerebellar Purkinje cell layer development(GO:0021680)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.4	GO:0007602	phototransduction(GO:0007602)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.2	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.1	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.0	GO:0071364	response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.0	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0032634	interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0	0.1	GO:0046688	response to copper ion(GO:0046688)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.5	GO:0007272	ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	1.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.3	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0042491	auditory receptor cell differentiation(GO:0042491)
0.0	0.2	GO:0042461	photoreceptor cell development(GO:0042461)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0072189	ureter development(GO:0072189)
0.0	0.5	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	0.0	GO:0014010	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626) Schwann cell proliferation(GO:0014010)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701) relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.0	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0009713	catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0	0.1	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0051883	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.0	GO:0010923	negative regulation of phosphatase activity(GO:0010923) negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.0	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.0	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.0	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0030201	heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0	0.1	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.0	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397) interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0060042	retina morphogenesis in camera-type eye(GO:0060042)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0030858	positive regulation of epithelial cell differentiation(GO:0030858)
0.0	0.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.5	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.6	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.7	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.4	GO:0071437	invadopodium(GO:0071437)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0031904	endosome lumen(GO:0031904)
0.1	0.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	1.1	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.4	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.4	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0002102	podosome(GO:0002102)
0.1	0.2	GO:0044215	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	0.4	GO:0031527	filopodium membrane(GO:0031527)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.5	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.4	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	1.1	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.4	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.5	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.4	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.3	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	1.0	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0043256	laminin complex(GO:0043256)
0.0	0.6	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0044304	main axon(GO:0044304)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.8	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.2	GO:1904949	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	0.3	GO:0001533	cornified envelope(GO:0001533)
0.0	0.0	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	1.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.3	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	1.2	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.1	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:1903561	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0042627	chylomicron(GO:0042627)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.6	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.4	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.6	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0001601	peptide YY receptor activity(GO:0001601)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.3	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.2	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1	0.2	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.2	GO:0045545	syndecan binding(GO:0045545)
0.1	0.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.4	GO:0000828	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.6	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.1	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.2	GO:0042805	actinin binding(GO:0042805)
0.1	0.5	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.1	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.6	GO:0004385	guanylate kinase activity(GO:0004385)
0.1	0.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.4	GO:0030507	spectrin binding(GO:0030507)
0.1	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.4	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.2	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.3	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.7	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.5	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.7	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.7	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.4	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.3	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.5	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.3	GO:0051117	ATPase binding(GO:0051117)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.4	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.0	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.0	GO:0045159	myosin II binding(GO:0045159)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.2	GO:0030291	protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0	0.0	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.0	GO:0004476	mannose-6-phosphate isomerase activity(GO:0004476)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.0	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.0	GO:0004500	dopamine beta-monooxygenase activity(GO:0004500)
0.0	0.5	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.2	GO:0004522	ribonuclease A activity(GO:0004522)
0.0	0.0	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.0	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	3.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	2.6	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.5	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.9	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.2	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.8	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.3	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.9	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	1.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	0.9	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	0.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	0.1	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.6	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.4	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.0	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.7	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.2	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.5	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.6	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.0	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.0	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.0	0.2	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins

Results for GATA5

Z-value: 3.33

Motif logo

Transcription factors associated with GATA5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the GATA5 motif across conditions

Conditions sorted by the z-value of the GATA5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: