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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GATA6

Z-value: 0.20

Motif logo

Transcription factors associated with GATA6

Gene Symbol	Gene ID	Gene Info
GATA6 Ensembl NCBI GeneCards UniProt	ENSG00000141448.4	GATA6

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GATA6	chr18_19751318_19751469	499	0.731776	0.84	4.6e-03	Click!
GATA6	chr18_19750904_19751196	156	0.938007	0.79	1.1e-02	Click!
GATA6	chr18_19747454_19747605	1875	0.266572	0.78	1.4e-02	Click!
GATA6	chr18_19749604_19749975	385	0.811827	0.73	2.6e-02	Click!
GATA6	chr18_19751508_19751659	689	0.608823	0.68	4.4e-02	Click!

Activity of the GATA6 motif across conditions

Conditions sorted by the z-value of the GATA6 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_54074428_54074776	0.03	DKK1	dickkopf WNT signaling pathway inhibitor 1	546	0.57
chr14_75748202_75748353	0.03	FOS	FBJ murine osteosarcoma viral oncogene homolog	1381	0.38
chr9_21550613_21551072	0.02	MIR31HG	MIR31 host gene (non-protein coding)	8826	0.18
chr7_116312981_116313724	0.02	MET	met proto-oncogene	893	0.68
chr20_11871067_11871503	0.02	BTBD3	BTB (POZ) domain containing 3	86	0.98
chr10_70817732_70817883	0.02	SRGN	serglycin	30067	0.15
chr10_119124215_119124366	0.02	ENSG00000222197	.	6423	0.22
chr15_80747723_80747953	0.02	RP11-210M15.1		10345	0.19
chr1_163039657_163039882	0.02	RGS4	regulator of G-protein signaling 4	618	0.82
chr18_28783722_28783891	0.02	DSC1	desmocollin 1	40987	0.14
chr12_123184919_123185107	0.02	HCAR2	hydroxycarboxylic acid receptor 2	2877	0.21
chr22_46480171_46480322	0.02	FLJ27365	hsa-mir-4763	1637	0.21
chr4_122706400_122706716	0.02	EXOSC9	exosome component 9	15914	0.15
chr5_178712201_178712352	0.02	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	60155	0.14
chr19_7460961_7461112	0.02	ARHGEF18	Rho/Rac guanine nucleotide exchange factor (GEF) 18	998	0.35
chr2_122353801_122354268	0.02	ENSG00000222467	.	6706	0.21
chr3_187009488_187009765	0.02	MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	20	0.98
chr4_122614681_122615038	0.02	ANXA5	annexin A5	3258	0.3
chr8_33422706_33423010	0.02	RNF122	ring finger protein 122	1785	0.28
chr12_88972313_88972545	0.02	KITLG	KIT ligand	1809	0.39
chr3_98609388_98609782	0.02	DCBLD2	discoidin, CUB and LCCL domain containing 2	10430	0.18
chr21_38711458_38711729	0.02	AP001437.1		26641	0.16
chr10_94180631_94180859	0.02	ENSG00000207895	.	20316	0.21
chr18_59660374_59660538	0.02	RNF152	ring finger protein 152	98992	0.08
chr4_129243818_129244169	0.02	PGRMC2	progesterone receptor membrane component 2	34009	0.24
chr16_8958188_8958339	0.02	CARHSP1	calcium regulated heat stable protein 1, 24kDa	2629	0.18
chr12_123198449_123198600	0.02	HCAR3	hydroxycarboxylic acid receptor 3	2915	0.19
chr19_10764777_10764928	0.02	ILF3	interleukin enhancer binding factor 3, 90kDa	85	0.95
chr16_84328151_84329018	0.02	WFDC1	WAP four-disulfide core domain 1	132	0.94
chr7_130594902_130595108	0.02	ENSG00000226380	.	32707	0.2
chr7_87935974_87936151	0.02	STEAP4	STEAP family member 4	133	0.97
chr5_17218970_17219230	0.02	BASP1	brain abundant, membrane attached signal protein 1	1431	0.35
chr5_180677774_180677925	0.02	GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	2753	0.1
chr6_108886554_108887901	0.02	FOXO3	forkhead box O3	5158	0.32
chr2_8816989_8817431	0.02	AC011747.7		1254	0.45
chr16_53906990_53907141	0.01	FTO	fat mass and obesity associated	13764	0.26
chr1_181104582_181104733	0.01	IER5	immediate early response 5	47019	0.16
chr12_8851550_8851701	0.01	RIMKLB	ribosomal modification protein rimK-like family member B	817	0.59
chr7_92324656_92325109	0.01	ENSG00000206763	.	6246	0.27
chr4_126253702_126253855	0.01	FAT4	FAT atypical cadherin 4	16224	0.25
chr2_197852750_197853145	0.01	ANKRD44	ankyrin repeat domain 44	12279	0.25
chr1_234041439_234041955	0.01	SLC35F3	solute carrier family 35, member F3	1018	0.65
chr17_58821066_58821723	0.01	ENSG00000252534	.	5013	0.22
chr8_25073004_25073155	0.01	DOCK5	dedicator of cytokinesis 5	30699	0.2
chr16_10174074_10174418	0.01	RP11-895K13.2		46705	0.18
chr7_134463594_134463964	0.01	CALD1	caldesmon 1	385	0.92
chr12_46554202_46554353	0.01	SLC38A1	solute carrier family 38, member 1	107207	0.07
chr1_79306379_79306727	0.01	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	77017	0.11
chr10_14083265_14083416	0.01	FRMD4A	FERM domain containing 4A	32808	0.17
chr2_24306708_24307223	0.01	TP53I3	tumor protein p53 inducible protein 3	216	0.89
chr22_30176981_30177234	0.01	UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X	13744	0.12
chr2_9350074_9350237	0.01	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	3261	0.37
chr2_227767802_227767953	0.01	RHBDD1	rhomboid domain containing 1	3551	0.31
chr9_137248904_137249055	0.01	ENSG00000263897	.	22278	0.21
chr7_114056620_114056771	0.01	FOXP2	forkhead box P2	1317	0.5
chrX_46699952_46700103	0.01	RP2	retinitis pigmentosa 2 (X-linked recessive)	3652	0.28
chr6_44420303_44420454	0.01	ENSG00000266619	.	17000	0.18
chr7_134330596_134330773	0.01	BPGM	2,3-bisphosphoglycerate mutase	876	0.7
chr3_114477625_114477831	0.01	ZBTB20	zinc finger and BTB domain containing 20	59	0.98
chr8_17600844_17600995	0.01	ENSG00000212280	.	4708	0.19
chr13_109624872_109625023	0.01	MYO16	myosin XVI	86430	0.1
chr8_70404668_70405416	0.01	SULF1	sulfatase 1	14	0.99
chr5_138774627_138774795	0.01	DNAJC18	DnaJ (Hsp40) homolog, subfamily C, member 18	504	0.67
chr17_57789761_57790061	0.01	VMP1	vacuole membrane protein 1	4828	0.18
chr4_78124065_78124216	0.01	CCNG2	cyclin G2	44561	0.16
chrX_151140603_151140985	0.01	GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	2349	0.22
chr2_217232127_217232304	0.01	MARCH4	membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase	4535	0.19
chr8_93107061_93107485	0.01	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	170	0.98
chr8_22516019_22516377	0.01	BIN3	bridging integrator 3	10428	0.11
chr2_37870062_37870489	0.01	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	4526	0.29
chr3_64174748_64175187	0.01	PRICKLE2-AS3	PRICKLE2 antisense RNA 3	1747	0.38
chr11_118958508_118958659	0.01	HMBS	hydroxymethylbilane synthase	110	0.9
chr5_59082098_59082249	0.01	PDE4D	phosphodiesterase 4D, cAMP-specific	17702	0.28
chr3_128712183_128712559	0.01	KIAA1257	KIAA1257	548	0.71
chr16_22307896_22308092	0.01	POLR3E	polymerase (RNA) III (DNA directed) polypeptide E (80kD)	736	0.63
chr13_80065629_80065780	0.01	NDFIP2	Nedd4 family interacting protein 2	10116	0.21
chr10_107734876_107735027	0.01	ENSG00000207068	.	440534	0.01
chr6_12324871_12325022	0.01	EDN1	endothelin 1	34350	0.22
chr1_161593652_161593803	0.01	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	7095	0.12
chr10_29607372_29607594	0.01	LYZL1	lysozyme-like 1	29493	0.23
chr5_86409630_86409781	0.01	ENSG00000265919	.	1066	0.58
chr4_103605681_103605832	0.01	MANBA	mannosidase, beta A, lysosomal	76334	0.09
chr4_168155836_168156001	0.01	SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	10	0.99
chr12_53896533_53896684	0.01	TARBP2	TAR (HIV-1) RNA binding protein 2	773	0.43
chr10_121497247_121497413	0.01	INPP5F	inositol polyphosphate-5-phosphatase F	11721	0.21
chr6_106577027_106577713	0.01	RP1-134E15.3		29355	0.19
chr7_87503839_87503990	0.01	DBF4	DBF4 homolog (S. cerevisiae)	1630	0.34
chr15_96936172_96936352	0.01	AC087477.1	Uncharacterized protein	31775	0.16
chr11_81727672_81727823	0.01	ENSG00000264110	.	125869	0.06
chr2_219152582_219152771	0.01	TMBIM1	transmembrane BAX inhibitor motif containing 1	650	0.54
chr8_47819479_47819630	0.01	ENSG00000252594	.	76882	0.12
chr2_169952320_169952546	0.01	AC007556.3		4820	0.24
chr3_162013497_162013648	0.01	OTOL1	otolin 1	798976	0.0
chr7_6433170_6433329	0.01	RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	19079	0.16
chr5_59190026_59190177	0.01	PDE4D	phosphodiesterase 4D, cAMP-specific	476	0.89
chr8_27629358_27630074	0.01	ESCO2	establishment of sister chromatid cohesion N-acetyltransferase 2	250	0.64
chr9_132098034_132098185	0.01	ENSG00000242281	.	34631	0.17
chr6_153451642_153452011	0.01	RGS17	regulator of G-protein signaling 17	558	0.79
chr4_13628130_13628980	0.01	BOD1L1	biorientation of chromosomes in cell division 1-like 1	792	0.46
chr7_32243948_32244107	0.01	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	94914	0.09
chr17_77001615_77001766	0.01	CANT1	calcium activated nucleotidase 1	4122	0.17
chr10_31873172_31873323	0.01	ENSG00000222412	.	171817	0.03
chr10_24528419_24528570	0.01	KIAA1217	KIAA1217	370	0.91
chr3_28337245_28337396	0.01	AZI2	5-azacytidine induced 2	36578	0.17
chr15_63220786_63221067	0.01	RP11-1069G10.1		44693	0.15
chr7_50564803_50564954	0.01	AC018705.5		34579	0.15
chr14_54954818_54955652	0.01	GMFB	glia maturation factor, beta	141	0.96
chr6_32120885_32121204	0.01	PPT2	palmitoyl-protein thioesterase 2	174	0.48
chr6_71997364_71997515	0.01	OGFRL1	opioid growth factor receptor-like 1	1067	0.53
chr16_67196775_67197002	0.01	HSF4	heat shock transcription factor 4	400	0.59
chr1_68640038_68640228	0.01	ENSG00000221203	.	9160	0.22
chr5_134692650_134692921	0.01	C5orf66	chromosome 5 open reading frame 66	19156	0.17
chr2_237600423_237600574	0.01	ACKR3	atypical chemokine receptor 3	122214	0.06
chr9_89738562_89738713	0.01	C9orf170	chromosome 9 open reading frame 170	24922	0.26
chr12_11948851_11949002	0.01	ETV6	ets variant 6	43491	0.19
chr15_35600951_35601102	0.01	ENSG00000265102	.	63539	0.15
chr1_65453023_65453174	0.01	JAK1	Janus kinase 1	20911	0.19
chr2_3527046_3527197	0.01	ADI1	acireductone dioxygenase 1	3614	0.17
chr1_161136284_161136792	0.01	PPOX	protoporphyrinogen oxidase	237	0.79
chr14_55915419_55915570	0.01	TBPL2	TATA box binding protein like 2	7950	0.23
chr22_33141802_33142090	0.01	LL22NC01-116C6.1		37217	0.18
chr4_159593239_159593390	0.01	ETFDH	electron-transferring-flavoprotein dehydrogenase	37	0.59
chr6_143193241_143193570	0.01	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	35221	0.21
chr8_103665091_103665311	0.01	KLF10	Kruppel-like factor 10	1402	0.49
chr4_87898598_87898749	0.01	AFF1	AF4/FMR2 family, member 1	29467	0.2
chr2_143631756_143631956	0.01	KYNU	kynureninase	3211	0.39
chr2_111229667_111229818	0.01	LIMS3	LIM and senescent cell antigen-like-containing domain protein 3; Uncharacterized protein; cDNA FLJ59124, highly similar to Particularly interesting newCys-His protein; cDNA, FLJ79109, highly similar to Particularly interesting newCys-His protein	651	0.43
chr2_30670110_30671067	0.01	LCLAT1	lysocardiolipin acyltransferase 1	319	0.92
chr8_96236254_96236405	0.01	C8orf37	chromosome 8 open reading frame 37	45100	0.16
chr15_67992319_67992470	0.01	MAP2K5	mitogen-activated protein kinase kinase 5	59503	0.14
chr6_26327913_26328565	0.01	ENSG00000252399	.	25025	0.08
chr4_82487360_82487596	0.01	RASGEF1B	RasGEF domain family, member 1B	94409	0.09
chr15_35331378_35331529	0.01	ZNF770	zinc finger protein 770	50965	0.14
chr6_37790580_37790731	0.01	ZFAND3	zinc finger, AN1-type domain 3	2937	0.24
chr22_31618868_31619019	0.01	ENSG00000199695	.	104	0.94
chr2_25599883_25600214	0.01	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	34589	0.16
chr4_70778543_70778694	0.01	CSN1S1	casein alpha s1	18181	0.18
chr4_10182385_10182585	0.01	WDR1	WD repeat domain 1	63912	0.11
chr3_14211699_14211850	0.01	LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)	8084	0.16
chr18_3306098_3306249	0.01	MYL12B	myosin, light chain 12B, regulatory	43219	0.12
chr3_104552670_104552821	0.01	ALCAM	activated leukocyte cell adhesion molecule	533008	0.0
chr6_138147763_138147914	0.01	RP11-356I2.4		807	0.68
chr17_15159258_15159409	0.01	ENSG00000265110	.	4320	0.16
chr10_35595852_35596003	0.01	RP11-324I22.4		13999	0.18
chr19_34216636_34216787	0.01	CHST8	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8	41277	0.18
chr17_38463018_38463169	0.01	RARA	retinoic acid receptor, alpha	2351	0.2
chr12_27093586_27093737	0.01	FGFR1OP2	FGFR1 oncogene partner 2	2228	0.23
chr14_70227453_70227703	0.01	SRSF5	serine/arginine-rich splicing factor 5	6232	0.23
chr16_84336242_84336393	0.01	RP11-558A11.2		5726	0.16
chr6_111794162_111794313	0.01	REV3L	REV3-like, polymerase (DNA directed), zeta, catalytic subunit	10177	0.2
chr10_70096270_70096993	0.01	PBLD	phenazine biosynthesis-like protein domain containing	3825	0.2
chr9_89598436_89598587	0.01	GAS1	growth arrest-specific 1	36407	0.23
chr11_5617858_5618363	0.01	TRIM6	tripartite motif containing 6	74	0.6
chr6_132452290_132452699	0.01	ENSG00000265669	.	16091	0.27
chr11_34607506_34607749	0.01	EHF	ets homologous factor	35031	0.19
chr1_177151039_177151190	0.01	ENSG00000222749	.	4474	0.23
chr18_46460407_46461027	0.01	SMAD7	SMAD family member 7	14158	0.24
chr18_42746929_42747122	0.01	RP11-846C15.2		14054	0.26
chr18_74826722_74826987	0.01	MBP	myelin basic protein	9637	0.3
chr1_34368317_34368468	0.01	RP5-1007G16.1		27325	0.2
chr11_109293842_109294216	0.01	C11orf87	chromosome 11 open reading frame 87	1183	0.65
chr2_242479985_242480602	0.01	BOK	BCL2-related ovarian killer	17843	0.12
chr10_77190038_77190238	0.01	RP11-399K21.10		1208	0.5
chr6_56598112_56598263	0.01	DST	dystonin	52490	0.16
chrX_123161918_123162069	0.01	STAG2	stromal antigen 2	64973	0.12
chr15_96590422_96590657	0.01	NR2F2-AS1	NR2F2 antisense RNA 1	175745	0.03
chr2_110656312_110656910	0.01	LIMS3	LIM and senescent cell antigen-like domains 3	343	0.93
chr12_122613090_122613241	0.01	MLXIP	MLX interacting protein	738	0.67
chr6_36187187_36187338	0.01	BRPF3	bromodomain and PHD finger containing, 3	15071	0.15
chr2_28867267_28867418	0.01	PLB1	phospholipase B1	13889	0.18
chr16_70779928_70780079	0.01	RP11-394B2.6		957	0.42
chr12_129349404_129349555	0.01	GLT1D1	glycosyltransferase 1 domain containing 1	798	0.73
chr1_201952184_201952974	0.01	RNPEP	arginyl aminopeptidase (aminopeptidase B)	121	0.93
chr11_100719851_100720002	0.01	ENSG00000200047	.	9565	0.23
chr4_155728508_155728667	0.01	ENSG00000252604	.	17144	0.15
chr4_97494543_97494694	0.01	ENSG00000201640	.	224429	0.02
chr8_17220397_17220671	0.01	MTMR7	myotubularin related protein 7	50302	0.15
chr1_181122215_181122496	0.01	IER5	immediate early response 5	64717	0.12
chr2_85199843_85200208	0.01	KCMF1	potassium channel modulatory factor 1	701	0.74
chr2_153349112_153349263	0.01	FMNL2	formin-like 2	126905	0.06
chr12_6959922_6960405	0.01	CDCA3	cell division cycle associated 3	250	0.75
chr13_96332061_96332487	0.01	DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	2862	0.29
chr1_65886473_65887602	0.01	LEPR	leptin receptor	634	0.48
chr3_72092545_72092696	0.01	ENSG00000239250	.	216292	0.02
chr15_89348318_89348469	0.01	ACAN	aggrecan	1403	0.51
chr5_14026093_14026244	0.01	DNAH5	dynein, axonemal, heavy chain 5	81516	0.11
chrX_39921638_39921789	0.01	BCOR	BCL6 corepressor	477	0.9
chr12_76100609_76100760	0.01	ENSG00000251893	.	17600	0.22
chr13_111365021_111365232	0.01	ING1	inhibitor of growth family, member 1	43	0.98
chr13_99193927_99194078	0.01	STK24	serine/threonine kinase 24	19750	0.2
chr8_28565361_28565512	0.01	EXTL3	exostosin-like glycosyltransferase 3	2439	0.28
chr1_52113963_52114114	0.01	OSBPL9	oxysterol binding protein-like 9	21185	0.19
chr7_23513086_23513237	0.01	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	3075	0.22
chr3_23960351_23960502	0.01	RPL15	ribosomal protein L15	1230	0.41
chrX_151999580_152000195	0.01	NSDHL	NAD(P) dependent steroid dehydrogenase-like	346	0.63
chr1_27125657_27125808	0.01	PIGV	phosphatidylinositol glycan anchor biosynthesis, class V	10313	0.11
chr1_23610032_23610183	0.01	HNRNPR	heterogeneous nuclear ribonucleoprotein R	60648	0.08
chr15_86098904_86099149	0.01	AKAP13	A kinase (PRKA) anchor protein 13	349	0.88
chr16_57798470_57798621	0.01	KIFC3	kinesin family member C3	244	0.9
chr11_78356519_78356693	0.01	TENM4	teneurin transmembrane protein 4	56443	0.12