Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GCM1

Z-value: 1.01

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Transcription factors associated with GCM1

Gene Symbol Gene ID Gene Info
GCM1
ENSG00000137270.10 GCM1

Activity of the GCM1 motif across conditions

Conditions sorted by the z-value of the GCM1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_209678_209938 0.80 DUSP22
 dual specificity phosphatase 22
 81822
 0.11
chr17_4389201_4389708 0.72 RP13-580F15.2
194
 0.92
chr12_76425402_76425553 0.69 PHLDA1
 pleckstrin homology-like domain, family A, member 1
 93
 0.95
chr11_118215661_118215850 0.65 CD3G
 CD3g molecule, gamma (CD3-TCR complex)
 684
 0.53
chr11_117858339_117858806 0.61 IL10RA
 interleukin 10 receptor, alpha
 1463
 0.41
chr20_34078435_34078749 0.60 RP3-477O4.14
151
 0.92
chr11_67186046_67186291 0.59 PPP1CA
 protein phosphatase 1, catalytic subunit, alpha isozyme
 2484
 0.1
chr21_46334019_46334170 0.57 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 104
 0.94
chr7_142430842_142430993 0.56 PRSS1
 protease, serine, 1 (trypsin 1)
 26402
 0.17
chr1_39500021_39500217 0.54 NDUFS5
 NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
 8129
 0.18
chr5_175461420_175461571 0.50 THOC3
 THO complex 3
 188
 0.93
chr19_6668929_6669193 0.50 TNFSF14
 tumor necrosis factor (ligand) superfamily, member 14
 1067
 0.44
chr16_29675034_29675898 0.48 QPRT
 quinolinate phosphoribosyltransferase
 866
 0.35
chr17_72919947_72920111 0.47 OTOP2
 otopetrin 2
 341
 0.64
chr3_50647795_50648029 0.46 CISH
 cytokine inducible SH2-containing protein
 1291
 0.31
chr19_18722743_18723001 0.45 TMEM59L
 transmembrane protein 59-like
 810
 0.42
chr11_102190417_102190590 0.45 BIRC3
 baculoviral IAP repeat containing 3
 2209
 0.28
chr7_45016674_45016991 0.44 MYO1G
 myosin IG
 1865
 0.25
chr2_10471742_10471998 0.43 HPCAL1
 hippocalcin-like 1
 28044
 0.15
chr3_151916550_151916780 0.43 MBNL1
 muscleblind-like splicing regulator 1
 69164
 0.11
chr19_49977836_49978103 0.43 FLT3LG
 fms-related tyrosine kinase 3 ligand
 110
 0.88
chr11_1911215_1911366 0.42 C11orf89
 chromosome 11 open reading frame 89
 794
 0.46
chr2_173327465_173327877 0.41 AC078883.3
3069
 0.24
chr10_46075820_46076565 0.41 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
 13747
 0.25
chrY_1604612_1604993 0.41 NA
 NA
 > 106
 NA
chr7_158936828_158937151 0.41 VIPR2
 vasoactive intestinal peptide receptor 2
 555
 0.87
chr1_1148809_1149188 0.40 TNFRSF4
 tumor necrosis factor receptor superfamily, member 4
 514
 0.56
chrX_53251626_53252025 0.39 KDM5C
 lysine (K)-specific demethylase 5C
 2533
 0.26
chr8_134509191_134509342 0.39 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2338
 0.44
chr17_73840046_73840332 0.39 UNC13D
 unc-13 homolog D (C. elegans)
 226
 0.84
chrX_1654663_1654996 0.39 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 1171
 0.53
chr13_74095292_74095443 0.39 ENSG00000206697
 .
 294083
 0.01
chr17_66233779_66233987 0.38 AMZ2
 archaelysin family metallopeptidase 2
 9832
 0.16
chr4_89884993_89885181 0.38 FAM13A
 family with sequence similarity 13, member A
 65964
 0.13
chr1_154977279_154977430 0.38 ZBTB7B
 zinc finger and BTB domain containing 7B
 2059
 0.13
chr3_182193185_182193336 0.38 RP11-225N10.1
317922
 0.01
chr17_74964898_74965186 0.37 ENSG00000267568
 .
 137
 0.97
chr13_41227499_41227650 0.37 FOXO1
 forkhead box O1
 13160
 0.24
chr7_37382547_37382746 0.36 ELMO1
 engulfment and cell motility 1
 137
 0.97
chr17_75378484_75378635 0.36 SEPT9
 septin 9
 2354
 0.25
chr9_132648514_132648803 0.36 FNBP1
 formin binding protein 1
 32931
 0.12
chr19_12906733_12906884 0.36 CTD-2659N19.10
829
 0.32
chr19_39282465_39283038 0.36 LGALS7B
 lectin, galactoside-binding, soluble, 7B
 2900
 0.11
chr2_131851229_131851413 0.35 FAM168B
 family with sequence similarity 168, member B
 288
 0.91
chr21_44105366_44105517 0.35 PDE9A
 phosphodiesterase 9A
 31518
 0.15
chr1_239880567_239880718 0.35 ENSG00000233355
 .
 1724
 0.38
chr21_30809062_30809213 0.35 ENSG00000239171
 .
 47327
 0.13
chr17_79925387_79925672 0.35 NOTUM
 notum pectinacetylesterase homolog (Drosophila)
 5813
 0.07
chr22_37637445_37637596 0.34 RAC2
 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
 2768
 0.2
chr2_197030684_197030835 0.34 STK17B
 serine/threonine kinase 17b
 4965
 0.22
chrX_1653880_1654070 0.34 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 2025
 0.36
chr1_1004234_1004415 0.34 RNF223
 ring finger protein 223
 5363
 0.1
chr3_128507459_128507964 0.34 ENSG00000244232
 .
 3721
 0.22
chrY_1603880_1604065 0.34 NA
 NA
 > 106
 NA
chr9_134150778_134151758 0.34 FAM78A
 family with sequence similarity 78, member A
 666
 0.69
chr6_35267244_35267414 0.33 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 1700
 0.35
chr20_39410185_39410336 0.33 ENSG00000238908
 .
 72609
 0.12
chr17_43326081_43326290 0.33 CTD-2020K17.4
18
 0.93
chr8_22437536_22437787 0.33 PDLIM2
 PDZ and LIM domain 2 (mystique)
 3
 0.95
chr17_56417092_56417372 0.33 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 2513
 0.16
chr17_72353572_72353723 0.33 BTBD17
 BTB (POZ) domain containing 17
 4438
 0.13
chr10_134357786_134358024 0.33 INPP5A
 inositol polyphosphate-5-phosphatase, 40kDa
 6262
 0.23
chr1_160616915_160617313 0.33 SLAMF1
 signaling lymphocytic activation molecule family member 1
 29
 0.97
chr15_89438571_89438754 0.33 HAPLN3
 hyaluronan and proteoglycan link protein 3
 102
 0.97
chr10_135088206_135088485 0.33 ADAM8
 ADAM metallopeptidase domain 8
 2009
 0.18
chr17_73839317_73839828 0.32 UNC13D
 unc-13 homolog D (C. elegans)
 278
 0.8
chr16_1030186_1030337 0.32 AC009041.2
991
 0.29
chr5_67510861_67511301 0.32 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 467
 0.86
chr7_142021133_142021284 0.32 PRSS3P3
 protease, serine, 3 pseudogene 3
 31599
 0.19
chr9_136004184_136004335 0.32 RALGDS
 ral guanine nucleotide dissociation stimulator
 529
 0.71
chr16_8715324_8715502 0.32 METTL22
 methyltransferase like 22
 127
 0.97
chr14_105531964_105532391 0.32 GPR132
 G protein-coupled receptor 132
 395
 0.85
chr9_134148708_134148859 0.32 FAM78A
 family with sequence similarity 78, member A
 2873
 0.24
chr20_52463628_52463779 0.32 AC005220.3
92996
 0.08
chr11_64631996_64632371 0.32 EHD1
 EH-domain containing 1
 10955
 0.1
chr20_61426647_61427159 0.32 MRGBP
 MRG/MORF4L binding protein
 902
 0.44
chr12_109254375_109254526 0.32 DAO
 D-amino-acid oxidase
 1742
 0.29
chr5_32532579_32532730 0.31 SUB1
 SUB1 homolog (S. cerevisiae)
 730
 0.76
chr2_226329396_226329663 0.31 NYAP2
 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
 55932
 0.18
chr10_7453140_7453326 0.31 SFMBT2
 Scm-like with four mbt domains 2
 215
 0.96
chr3_50266787_50266938 0.31 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
 3138
 0.14
chr17_37309817_37310001 0.31 PLXDC1
 plexin domain containing 1
 424
 0.77
chr10_135089211_135089472 0.31 ADAM8
 ADAM metallopeptidase domain 8
 1013
 0.36
chr8_141606949_141607187 0.31 AGO2
 argonaute RISC catalytic component 2
 8919
 0.24
chr5_41869351_41870086 0.31 ENSG00000248668
 .
 414
 0.71
chr12_65063818_65064050 0.31 RP11-338E21.3
15135
 0.13
chr10_102414840_102414991 0.31 PAX2
 paired box 2
 90553
 0.07
chr16_88767682_88768006 0.31 RNF166
 ring finger protein 166
 833
 0.34
chr7_142168431_142168627 0.31 PRSS3P3
 protease, serine, 3 pseudogene 3
 178920
 0.03
chr15_31638589_31638828 0.30 KLF13
 Kruppel-like factor 13
 6572
 0.32
chr7_99764195_99764346 0.30 GAL3ST4
 galactose-3-O-sulfotransferase 4
 583
 0.47
chr15_45461761_45461912 0.30 RP11-519G16.2
706
 0.5
chr21_36420108_36421159 0.30 RUNX1
 runt-related transcription factor 1
 829
 0.77
chr7_105172345_105172532 0.30 RINT1
 RAD50 interactor 1
 94
 0.97
chr19_47221213_47221364 0.30 PRKD2
 protein kinase D2
 904
 0.37
chr17_55335025_55335422 0.29 MSI2
 musashi RNA-binding protein 2
 844
 0.72
chr21_46294862_46295073 0.29 PTTG1IP
 pituitary tumor-transforming 1 interacting protein
 1215
 0.36
chr8_101321788_101322100 0.29 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
 190
 0.96
chr17_56419518_56419935 0.29 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 5007
 0.12
chr10_88296004_88296305 0.29 RP11-77P6.2
14452
 0.18
chr14_22967453_22967632 0.29 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 11371
 0.1
chr7_38407258_38407409 0.29 AMPH
 amphiphysin
 95380
 0.09
chr20_18447768_18448009 0.29 DZANK1
 double zinc ribbon and ankyrin repeat domains 1
 59
 0.57
chr6_158403047_158403268 0.29 SYNJ2
 synaptojanin 2
 87
 0.97
chr17_3598807_3599359 0.28 P2RX5
 purinergic receptor P2X, ligand-gated ion channel, 5
 244
 0.86
chr11_615153_615351 0.28 IRF7
 interferon regulatory factor 7
 374
 0.7
chr7_142131561_142131712 0.28 PRSS3P3
 protease, serine, 3 pseudogene 3
 142027
 0.04
chr11_76340983_76341134 0.28 AP001189.4
27042
 0.16
chr8_121822100_121822251 0.28 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
 2208
 0.3
chr3_16327973_16328244 0.28 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 17360
 0.16
chr10_47640402_47640757 0.28 ANTXRLP1
 anthrax toxin receptor-like pseudogene 1
 4212
 0.25
chr4_143328016_143328342 0.28 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 24233
 0.29
chr22_29195834_29196065 0.28 XBP1
 X-box binding protein 1
 172
 0.86
chr4_40200080_40200394 0.28 RHOH
 ras homolog family member H
 1710
 0.4
chr2_30456250_30456532 0.28 LBH
 limb bud and heart development
 1345
 0.51
chr3_52259939_52260090 0.28 TLR9
 toll-like receptor 9
 165
 0.9
chr19_51945391_51945555 0.27 SIGLEC8
 sialic acid binding Ig-like lectin 8
 16233
 0.08
chr2_158298330_158298802 0.27 ENSG00000216054
 .
 504
 0.79
chr8_123931240_123931872 0.27 ZHX2
 zinc fingers and homeoboxes 2
 55932
 0.11
chr3_172237996_172238609 0.27 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 2963
 0.33
chr22_28314957_28315175 0.27 PITPNB
 phosphatidylinositol transfer protein, beta
 49
 0.79
chr19_1068869_1069054 0.27 HMHA1
 histocompatibility (minor) HA-1
 1464
 0.22
chr19_36444094_36444274 0.27 LRFN3
 leucine rich repeat and fibronectin type III domain containing 3
 16162
 0.09
chr17_61722686_61722837 0.27 MAP3K3
 mitogen-activated protein kinase kinase kinase 3
 22691
 0.13
chr19_3275241_3275448 0.27 AC010649.1
27575
 0.14
chr1_149294368_149294519 0.27 ENSG00000252105
 .
 8121
 0.17
chr16_29611589_29612053 0.27 ENSG00000266758
 .
 1235
 0.4
chr19_39261140_39261530 0.27 CAPN12
 calpain 12
 791
 0.41
chr9_133710099_133710496 0.27 ABL1
 c-abl oncogene 1, non-receptor tyrosine kinase
 156
 0.96
chr17_62982296_62982856 0.27 AMZ2P1
 archaelysin family metallopeptidase 2 pseudogene 1
 12941
 0.15
chr6_149866537_149867090 0.27 PPIL4
 peptidylprolyl isomerase (cyclophilin)-like 4
 361
 0.81
chr11_65184608_65185159 0.27 ENSG00000245532
 .
 27046
 0.09
chr2_73613117_73613352 0.27 ALMS1
 Alstrom syndrome 1
 348
 0.89
chr20_50158730_50159057 0.26 NFATC2
 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
 365
 0.92
chr16_80625165_80625316 0.26 RP11-525K10.3
28208
 0.14
chr9_139433380_139433586 0.26 RP11-413M3.4
3850
 0.11
chr1_153917802_153918374 0.26 DENND4B
 DENN/MADD domain containing 4B
 343
 0.75
chr19_7587803_7588090 0.26 MCOLN1
 mucolipin 1
 373
 0.72
chr12_54020323_54020579 0.26 ATF7
 activating transcription factor 7
 252
 0.78
chr13_41188216_41188367 0.26 FOXO1
 forkhead box O1
 52443
 0.14
chr7_50132272_50132698 0.26 ZPBP
 zona pellucida binding protein
 347
 0.89
chr5_103333318_103333469 0.25 ENSG00000201910
 .
 101182
 0.09
chr13_100027611_100027771 0.25 ENSG00000207719
 .
 19306
 0.2
chr16_67679075_67679512 0.25 RLTPR
 RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
 143
 0.91
chr14_69247883_69248049 0.25 ZFP36L1
 ZFP36 ring finger protein-like 1
 9994
 0.22
chr12_8084122_8084273 0.25 SLC2A3
 solute carrier family 2 (facilitated glucose transporter), member 3
 4585
 0.17
chr12_62381215_62381366 0.25 FAM19A2
 family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
 117419
 0.06
chr7_74867769_74867944 0.25 GATSL2
 GATS protein-like 2
 347
 0.82
chr8_142219075_142219226 0.25 DENND3
 DENN/MADD domain containing 3
 16720
 0.15
chr11_67176589_67176876 0.25 TBC1D10C
 TBC1 domain family, member 10C
 5072
 0.07
chr3_72787702_72787951 0.25 ENSG00000222838
 .
 46864
 0.17
chr9_139925276_139925479 0.25 FUT7
 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
 2085
 0.1
chr15_31637211_31637362 0.25 KLF13
 Kruppel-like factor 13
 5150
 0.33
chr21_44835049_44835200 0.25 SIK1
 salt-inducible kinase 1
 11884
 0.28
chr8_145049565_145049716 0.25 PLEC
 plectin
 97
 0.93
chr22_26975525_26975744 0.25 TPST2
 tyrosylprotein sulfotransferase 2
 10455
 0.15
chr16_30197801_30198230 0.25 RP11-455F5.5
1737
 0.15
chr10_121298283_121299012 0.25 RGS10
 regulator of G-protein signaling 10
 2602
 0.34
chr15_101137385_101137572 0.25 LINS
 lines homolog (Drosophila)
 337
 0.84
chr6_32159695_32160229 0.25 GPSM3
 G-protein signaling modulator 3
 683
 0.42
chrX_39796396_39796688 0.25 ENSG00000263972
 .
 99727
 0.08
chr12_122238871_122239022 0.25 RHOF
 ras homolog family member F (in filopodia)
 363
 0.83
chr8_145955389_145955540 0.25 AF186192.5
22783
 0.11
chr17_72270369_72270526 0.25 DNAI2
 dynein, axonemal, intermediate chain 2
 18
 0.96
chr12_57637378_57637612 0.24 NDUFA4L2
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
 3020
 0.13
chr1_159893254_159893502 0.24 TAGLN2
 transgelin 2
 129
 0.92
chr11_57434309_57434788 0.24 ZDHHC5
 zinc finger, DHHC-type containing 5
 671
 0.53
chr17_56405619_56405770 0.24 BZRAP1
 benzodiazepine receptor (peripheral) associated protein 1
 249
 0.73
chr11_75942946_75943097 0.24 WNT11
 wingless-type MMTV integration site family, member 11
 21241
 0.18
chr5_56246618_56246840 0.24 MIER3
 mesoderm induction early response 1, family member 3
 1211
 0.41
chrX_153672104_153672338 0.24 FAM50A
 family with sequence similarity 50, member A
 252
 0.79
chr4_76648928_76649551 0.24 G3BP2
 GTPase activating protein (SH3 domain) binding protein 2
 320
 0.66
chr14_21699419_21699570 0.24 HNRNPC
 heterogeneous nuclear ribonucleoprotein C (C1/C2)
 87
 0.97
chr4_84205732_84206158 0.24 COQ2
 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
 27
 0.98
chr4_151953272_151953579 0.24 LRBA
 LPS-responsive vesicle trafficking, beach and anchor containing
 16546
 0.19
chr10_3527542_3527740 0.24 RP11-184A2.3
265618
 0.02
chrX_21676275_21676631 0.24 KLHL34
 kelch-like family member 34
 5
 0.99
chr7_74653582_74653755 0.24 ENSG00000202021
 .
 59280
 0.12
chr9_123884533_123884959 0.24 CNTRL
 centriolin
 667
 0.74
chr1_179801278_179801429 0.24 RP11-12M5.3
14027
 0.16
chr18_18692022_18692792 0.24 ROCK1
 Rho-associated, coiled-coil containing protein kinase 1
 595
 0.77
chr1_203597376_203597536 0.24 ATP2B4
 ATPase, Ca++ transporting, plasma membrane 4
 1528
 0.48
chr3_186490205_186490406 0.24 ENSG00000207505
 .
 569
 0.51
chr13_114876143_114876405 0.23 RASA3-IT1
 RASA3 intronic transcript 1 (non-protein coding)
 1979
 0.38
chr8_134510645_134510921 0.23 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 821
 0.76
chr5_177236532_177236690 0.23 FAM153A
 family with sequence similarity 153, member A
 26212
 0.14
chr3_47422523_47422946 0.23 PTPN23
 protein tyrosine phosphatase, non-receptor type 23
 224
 0.51
chrX_14048139_14048340 0.23 GEMIN8
 gem (nuclear organelle) associated protein 8
 227
 0.95
chr12_58166072_58166294 0.23 METTL21B
 methyltransferase like 21B
 200
 0.5
chr8_142429304_142429455 0.23 PTP4A3
 protein tyrosine phosphatase type IVA, member 3
 2628
 0.19
chr12_53107613_53107764 0.23 KRT77
 keratin 77
 10441
 0.13
chr7_72568717_72568890 0.23 AC006995.8
43318
 0.1
chr17_78821534_78821685 0.23 RP11-28G8.1
42177
 0.14
chr1_184005297_184005448 0.23 COLGALT2
 collagen beta(1-O)galactosyltransferase 2
 1239
 0.54
chr1_155946704_155947008 0.23 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 1095
 0.29
chr2_85812315_85812466 0.23 VAMP5
 vesicle-associated membrane protein 5
 859
 0.38
chr1_151445972_151446221 0.23 POGZ
 pogo transposable element with ZNF domain
 14155
 0.11
chr9_114423460_114423756 0.23 GNG10
 guanine nucleotide binding protein (G protein), gamma 10
 7
 0.97
chr1_198638370_198638521 0.23 RP11-553K8.5
2255
 0.38
chr8_126447584_126447735 0.23 TRIB1
 tribbles pseudokinase 1
 1871
 0.39

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of GCM1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.1 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.1 0.3 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.1 0.2 GO:0032060 bleb assembly(GO:0032060)
0.1 0.3 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.1 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.1 0.2 GO:0002883 hypersensitivity(GO:0002524) regulation of hypersensitivity(GO:0002883)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.2 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.2 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0 0.2 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0048291 isotype switching to IgG isotypes(GO:0048291)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.4 GO:0010510 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.2 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.0 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.8 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.2 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.2 GO:0001562 response to protozoan(GO:0001562)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0032497 detection of molecule of bacterial origin(GO:0032490) detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0032202 telomere assembly(GO:0032202)
0.0 0.5 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.0 0.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:0051132 NK T cell proliferation(GO:0001866) NK T cell activation(GO:0051132)
0.0 0.1 GO:0032733 positive regulation of interleukin-10 production(GO:0032733)
0.0 0.2 GO:0032727 positive regulation of interferon-alpha production(GO:0032727)
0.0 0.1 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.0 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.0 GO:0046645 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0035587 purinergic receptor signaling pathway(GO:0035587)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0032608 interferon-beta production(GO:0032608)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0001783 B cell apoptotic process(GO:0001783)
0.0 0.0 GO:0002870 lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.0 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0060294 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.1 GO:0016556 mRNA modification(GO:0016556)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0042416 dopamine biosynthetic process(GO:0042416)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.0 GO:0051446 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.4 GO:0032479 regulation of type I interferon production(GO:0032479)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0003094 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0 0.0 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0045988 negative regulation of striated muscle contraction(GO:0045988)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0045579 positive regulation of B cell differentiation(GO:0045579)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.0 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.0 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.0 GO:0000239 pachytene(GO:0000239)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.3 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.0 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0070193 synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0007143 female meiotic division(GO:0007143)
0.0 0.0 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923) negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.0 GO:0030540 female genitalia development(GO:0030540)
0.0 0.1 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0033628 regulation of cell adhesion mediated by integrin(GO:0033628)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0003407 neural retina development(GO:0003407)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.4 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.1 GO:0034311 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.2 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.0 GO:0018242 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0070977 organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.0 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.5 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.0 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:0030903 notochord development(GO:0030903)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0002467 germinal center formation(GO:0002467)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0090218 positive regulation of lipid kinase activity(GO:0090218)
0.0 0.1 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.0 GO:0033622 integrin activation(GO:0033622)
0.0 0.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.0 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.0 GO:0071816 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032009 early phagosome(GO:0032009)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.4 GO:0000346 transcription export complex(GO:0000346)
0.1 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.2 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.5 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.1 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.2 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.4 GO:0016592 mediator complex(GO:0016592)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.4 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.4 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0035197 siRNA binding(GO:0035197)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.2 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.1 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.2 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.2 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0016502 G-protein coupled nucleotide receptor activity(GO:0001608) purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0046977 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.8 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.0 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.0 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.5 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.1 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.1 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.0 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.0 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.2 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0003823 antigen binding(GO:0003823)
0.0 0.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.4 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.1 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.5 PID ATM PATHWAY ATM pathway
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.7 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.8 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.6 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.6 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.0 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.1 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.0 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0 0.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus