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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for GCM2

Z-value: 1.64

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Transcription factors associated with GCM2

Gene Symbol	Gene ID	Gene Info
GCM2 Ensembl NCBI GeneCards UniProt	ENSG00000124827.6	glial cells missing transcription factor 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_10882334_10882485	GCM2	235	0.655479	0.42	2.6e-01	Click!
chr6_10882168_10882319	GCM2	69	0.717054	-0.42	2.6e-01	Click!
chr6_10884165_10884460	GCM2	2138	0.218969	0.10	7.9e-01	Click!

Activity of the GCM2 motif across conditions

Conditions sorted by the z-value of the GCM2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_38721330_38721617	0.74	CCR7	chemokine (C-C motif) receptor 7	238	0.92
chr18_32556796_32556947	0.68	MAPRE2	microtubule-associated protein, RP/EB family, member 2	21	0.99
chr19_18388821_18388972	0.59	JUND	jun D proto-oncogene	2843	0.13
chr1_47799579_47799893	0.58	CMPK1	cytidine monophosphate (UMP-CMP) kinase 1, cytosolic	150	0.95
chr10_11206834_11206985	0.55	CELF2	CUGBP, Elav-like family member 2	84	0.98
chr8_144358025_144358176	0.50	RP13-582O9.5		4919	0.11
chr14_23306583_23306834	0.49	MMP14	matrix metallopeptidase 14 (membrane-inserted)	187	0.87
chr5_179286017_179286230	0.46	CTC-241N9.1	Uncharacterized protein	110	0.66
chr7_116593207_116593413	0.46	ST7	suppression of tumorigenicity 7	18	0.9
chr1_78245652_78246225	0.45	FAM73A	family with sequence similarity 73, member A	345	0.48
chr17_5974794_5974945	0.45	WSCD1	WSC domain containing 1	441	0.9
chr19_47127517_47127701	0.45	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)	685	0.49
chr4_17578823_17578986	0.44	LAP3	leucine aminopeptidase 3	89	0.96
chr17_37558067_37558428	0.44	CTB-131K11.1		201	0.65
chr16_1032247_1032398	0.44	SOX8	SRY (sex determining region Y)-box 8	514	0.52
chr8_116678670_116678821	0.43	TRPS1	trichorhinophalangeal syndrome I	1463	0.59
chr1_38512756_38512948	0.42	POU3F1	POU class 3 homeobox 1	402	0.82
chr7_72300733_72300925	0.42	SBDSP1	Shwachman-Bodian-Diamond syndrome pseudogene 1	594	0.6
chr7_5336962_5337158	0.42	SLC29A4	solute carrier family 29 (equilibrative nucleoside transporter), member 4	14400	0.16
chr7_145813457_145813835	0.41	CNTNAP2	contactin associated protein-like 2	193	0.96
chrX_134049034_134049244	0.41	MOSPD1	motile sperm domain containing 1	118	0.96
chr5_159626613_159626831	0.41	CTB-127C13.1		620	0.46
chr22_29195834_29196065	0.41	XBP1	X-box binding protein 1	172	0.86
chrX_70287985_70288182	0.40	SNX12	sorting nexin 12	170	0.92
chr19_23869476_23869665	0.40	ZNF675	zinc finger protein 675	387	0.9
chr16_2015338_2015613	0.39	ENSG00000255198	.	290	0.55
chr10_104210626_104210853	0.39	ENSG00000269609	.	351	0.57
chr16_50583580_50583731	0.39	NKD1	naked cuticle homolog 1 (Drosophila)	1414	0.38
chrX_130937250_130937549	0.38	ENSG00000200587	.	135585	0.05
chr20_30948041_30948438	0.37	ASXL1	additional sex combs like 1 (Drosophila)	689	0.71
chr3_46934468_46934619	0.36	AC109583.1	Uncharacterized protein	4372	0.16
chr6_26571959_26572122	0.36	ABT1	activator of basal transcription 1	25140	0.13
chr17_40119579_40119751	0.36	CNP	2',3'-cyclic nucleotide 3' phosphodiesterase	136	0.94
chr19_21688744_21688977	0.36	ZNF429	zinc finger protein 429	454	0.87
chr20_62715149_62715509	0.35	C20orf201	chromosome 20 open reading frame 201	383	0.66
chr6_34393564_34393808	0.35	RPS10-NUDT3	RPS10-NUDT3 readthrough	139	0.61
chr1_61548685_61548897	0.35	NFIA	nuclear factor I/A	365	0.52
chr17_17643309_17643522	0.34	RAI1-AS1	RAI1 antisense RNA 1	30720	0.12
chr16_29623643_29623977	0.34	ENSG00000266758	.	13224	0.14
chr7_126988121_126988299	0.34	AC000123.4		1972	0.4
chr6_18397050_18397268	0.33	ENSG00000238458	.	5124	0.24
chr15_93446819_93447199	0.33	ENSG00000264173	.	620	0.48
chr12_115122776_115122995	0.33	TBX3	T-box 3	916	0.64
chr19_10531455_10531757	0.33	PDE4A	phosphodiesterase 4A, cAMP-specific	275	0.75
chr10_28491840_28491991	0.33	MPP7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	35751	0.21
chr15_89921416_89921567	0.33	ENSG00000207819	.	10243	0.19
chr17_34891354_34891543	0.32	PIGW	phosphatidylinositol glycan anchor biosynthesis, class W	45	0.91
chr13_41886064_41886695	0.32	NAA16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit	963	0.57
chr7_148396048_148396355	0.32	CUL1	cullin 1	197	0.75
chr5_177027484_177027704	0.32	B4GALT7	xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7	363	0.8
chr11_107328720_107328953	0.31	CWF19L2	CWF19-like 2, cell cycle control (S. pombe)	264	0.95
chr6_131456080_131456669	0.31	AKAP7	A kinase (PRKA) anchor protein 7	432	0.9
chr5_73982840_73982991	0.31	HEXB	hexosaminidase B (beta polypeptide)	1946	0.34
chr17_16256516_16256704	0.30	CENPV	centromere protein V	160	0.94
chr1_153963262_153963499	0.30	RPS27	ribosomal protein S27	142	0.9
chr6_26033320_26033579	0.30	HIST1H2AB	histone cluster 1, H2ab	347	0.65
chr5_96271059_96271537	0.30	LNPEP	leucyl/cystinyl aminopeptidase	130	0.96
chr2_26569875_26570036	0.30	GPR113	G protein-coupled receptor 113	270	0.84
chr3_53916371_53916541	0.30	ENSG00000222888	.	160	0.58
chr9_131903521_131903756	0.30	PPP2R4	protein phosphatase 2A activator, regulatory subunit 4	287	0.85
chr10_104170136_104170328	0.30	PSD	pleckstrin and Sec7 domain containing	8669	0.1
chrX_1572414_1572620	0.30	ASMTL	acetylserotonin O-methyltransferase-like	138	0.96
chr19_53104022_53104358	0.30	CTD-3099C6.11		2050	0.19
chr4_57931934_57932158	0.29	ENSG00000238541	.	40465	0.11
chr7_143533030_143533370	0.29	RP11-61L23.2		104	0.97
chr3_42846205_42846412	0.29	HIGD1A	HIG1 hypoxia inducible domain family, member 1A	285	0.84
chr11_100558368_100558828	0.29	CTD-2383M3.1		88	0.65
chrY_1522413_1522621	0.29	NA	NA	> 10⁶	NA
chr13_22057996_22058198	0.29	ZDHHC20	zinc finger, DHHC-type containing 20	24588	0.18
chr7_195524_195675	0.29	AC093627.12		1419	0.41
chr7_143318509_143318843	0.29	FAM115C	family with sequence similarity 115, member C	131	0.96
chr8_121744015_121744417	0.29	RP11-713M15.1		29277	0.22
chr19_47634546_47634940	0.29	SAE1	SUMO1 activating enzyme subunit 1	591	0.71
chr6_169990007_169990169	0.29	WDR27	WD repeat domain 27	70700	0.1
chr18_68326306_68326457	0.29	GTSCR1	Gilles de la Tourette syndrome chromosome region, candidate 1	8401	0.32
chr17_65241489_65241782	0.29	HELZ	helicase with zinc finger	332	0.69
chr3_119014697_119015414	0.29	ARHGAP31	Rho GTPase activating protein 31	1835	0.31
chr6_26032878_26033311	0.28	HIST1H2AB	histone cluster 1, H2ab	702	0.31
chr22_41940614_41940785	0.28	POLR3H	polymerase (RNA) III (DNA directed) polypeptide H (22.9kD)	89	0.96
chr2_101180136_101180337	0.28	PDCL3	phosducin-like 3	516	0.76
chr3_183966275_183966684	0.28	ALG3	ALG3, alpha-1,3- mannosyltransferase	244	0.79
chr17_79935874_79936121	0.28	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	222	0.82
chr19_15343730_15343881	0.28	EPHX3	epoxide hydrolase 3	53	0.97
chr22_50243479_50243664	0.28	ZBED4	zinc finger, BED-type containing 4	3919	0.22
chr11_35965131_35965474	0.28	LDLRAD3	low density lipoprotein receptor class A domain containing 3	229	0.93
chr9_116163187_116163544	0.28	ALAD	aminolevulinate dehydratase	35	0.96
chr6_26198818_26199250	0.28	HIST1H2AD	histone cluster 1, H2ad	437	0.34
chr21_33244491_33244642	0.28	HUNK	hormonally up-regulated Neu-associated kinase	1062	0.65
chr3_143566573_143567346	0.28	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	341	0.94
chr12_32871598_32871749	0.28	ENSG00000201563	.	13233	0.21
chr2_174829537_174830027	0.28	SP3	Sp3 transcription factor	501	0.89
chr14_23299131_23299994	0.28	MRPL52	mitochondrial ribosomal protein L52	304	0.6
chr17_7164973_7165404	0.27	CLDN7	claudin 7	474	0.52
chr7_99102295_99102499	0.27	ZKSCAN5	zinc finger with KRAB and SCAN domains 5	99	0.94
chrX_1514201_1514352	0.27	SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	2659	0.21
chr11_65154078_65154899	0.27	FRMD8	FERM domain containing 8	89	0.94
chr10_99093753_99093904	0.27	RP11-452K12.4		493	0.49
chr2_191745621_191745919	0.27	GLS	glutaminase	210	0.9
chr11_66035600_66035751	0.27	RP11-867G23.2		75	0.76
chr16_29823564_29823949	0.27	PRRT2	proline-rich transmembrane protein 2	192	0.68
chrY_1464199_1464350	0.27	NA	NA	> 10⁶	NA
chr16_86604479_86604706	0.27	RP11-463O9.5		3225	0.19
chrX_48693575_48693797	0.27	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor	349	0.78
chr1_16375359_16375546	0.27	CLCNKB	chloride channel, voltage-sensitive Kb	168	0.92
chr12_25956104_25956320	0.27	ENSG00000222950	.	23709	0.25
chr16_82661012_82661382	0.26	CDH13	cadherin 13	499	0.88
chr1_54844833_54844984	0.26	SSBP3	single stranded DNA binding protein 3	26269	0.19
chrX_153084272_153084494	0.26	PDZD4	PDZ domain containing 4	10968	0.09
chr19_20278322_20278527	0.26	ZNF486	zinc finger protein 486	341	0.87
chrX_53024151_53024564	0.26	FAM156A	family with sequence similarity 156, member A	194	0.95
chr15_49103006_49103287	0.26	CEP152	centrosomal protein 152kDa	38	0.76
chr2_230873136_230873287	0.26	ENSG00000206725	.	35180	0.13
chr22_51039548_51039740	0.26	MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	513	0.6
chr1_116711224_116711506	0.26	MAB21L3	mab-21-like 3 (C. elegans)	56989	0.14
chr11_307271_307422	0.26	IFITM2	interferon induced transmembrane protein 2	285	0.75
chr5_36878186_36878337	0.25	NIPBL	Nipped-B homolog (Drosophila)	1369	0.59
chr5_160974690_160974841	0.25	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	365	0.93
chr4_27050261_27050494	0.25	STIM2	stromal interaction molecule 2	40282	0.22
chr2_233387084_233387235	0.25	PRSS56	protease, serine, 56	1986	0.18
chr17_48619640_48620019	0.25	ENSG00000250286	.	3714	0.11
chrX_9320798_9321168	0.25	TBL1X	transducin (beta)-like 1X-linked	110352	0.07
chr15_74219539_74219761	0.25	LOXL1-AS1	LOXL1 antisense RNA 1	386	0.69
chr7_100859878_100860119	0.25	PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	697	0.4
chr11_66386268_66386833	0.25	RBM14	RNA binding motif protein 14	2364	0.12
chr1_10532708_10532986	0.25	DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	264	0.85
chr19_53466333_53466748	0.25	ZNF816	zinc finger protein 816	376	0.53
chr20_3788549_3788700	0.25	CDC25B	cell division cycle 25B	11546	0.11
chr14_90528183_90528389	0.25	KCNK13	potassium channel, subfamily K, member 13	177	0.97
chr2_66664825_66665240	0.24	MEIS1	Meis homeobox 1	93	0.96
chr6_25732828_25732979	0.24	HIST1H2BA	histone cluster 1, H2ba	5766	0.17
chr5_176023977_176024277	0.24	GPRIN1	G protein regulated inducer of neurite outgrowth 1	13007	0.11
chr20_43211231_43211439	0.24	PKIG	protein kinase (cAMP-dependent, catalytic) inhibitor gamma	145	0.95
chr17_21030010_21030234	0.24	DHRS7B	dehydrogenase/reductase (SDR family) member 7B	155	0.96
chr5_60921640_60922072	0.24	C5orf64	chromosome 5 open reading frame 64	11780	0.22
chr8_136556013_136556164	0.24	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	1142	0.65
chr5_39526290_39526441	0.24	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	63963	0.15
chr9_4741404_4741742	0.24	AK3	adenylate kinase 3	255	0.92
chr6_27805401_27805998	0.24	HIST1H2AK	histone cluster 1, H2ak	418	0.5
chr5_158533512_158533971	0.24	EBF1	early B-cell factor 1	6972	0.26
chr15_96952221_96952372	0.24	AC087477.1	Uncharacterized protein	47809	0.13
chr1_223536976_223537611	0.24	SUSD4	sushi domain containing 4	108	0.97
chr17_42733796_42734027	0.24	C17orf104	chromosome 17 open reading frame 104	71	0.96
chr2_220299665_220299816	0.24	SPEG	SPEG complex locus	172	0.9
chr6_27101035_27101630	0.24	HIST1H2AG	histone cluster 1, H2ag	500	0.53
chr7_66459685_66459882	0.24	SBDS	Shwachman-Bodian-Diamond syndrome	805	0.55
chr21_44922813_44922964	0.24	SIK1	salt-inducible kinase 1	75880	0.1
chr10_75646822_75647179	0.24	CAMK2G	calcium/calmodulin-dependent protein kinase II gamma	12657	0.12
chr1_40562359_40562905	0.24	PPT1	palmitoyl-protein thioesterase 1	93	0.97
chr11_46450627_46450944	0.24	AMBRA1	autophagy/beclin-1 regulator 1	11240	0.15
chr22_36173418_36173584	0.23	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	578	0.82
chr1_145472532_145473065	0.23	ANKRD34A	ankyrin repeat domain 34A	2290	0.15
chr19_38397857_38398210	0.23	SIPA1L3	signal-induced proliferation-associated 1 like 3	165	0.87
chr6_44356035_44356348	0.23	CDC5L	cell division cycle 5-like	929	0.54
chr2_112895743_112895934	0.23	FBLN7	fibulin 7	124	0.97
chr2_179344744_179345027	0.23	PLEKHA3	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3	310	0.82
chr15_60883034_60883482	0.23	RORA	RAR-related orphan receptor A	1482	0.47
chr13_47159131_47159282	0.23	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	31811	0.22
chr17_75372530_75372681	0.23	SEPT9	septin 9	440	0.62
chr6_157935851_157936002	0.23	ENSG00000266617	.	14238	0.27
chr3_180320366_180320663	0.23	TTC14	tetratricopeptide repeat domain 14	164	0.95
chr19_50393038_50393189	0.23	ENSG00000263462	.	1681	0.14
chr7_138665064_138665872	0.23	KIAA1549	KIAA1549	596	0.79
chr19_21580209_21580417	0.23	ZNF493	zinc finger protein 493	345	0.9
chr1_204485580_204485809	0.23	MDM4	Mdm4 p53 binding protein homolog (mouse)	75	0.97
chr21_33783968_33784413	0.23	EVA1C	eva-1 homolog C (C. elegans)	499	0.74
chr17_56592126_56592438	0.23	MTMR4	myotubularin related protein 4	297	0.84
chr7_149746137_149746288	0.22	ATP6V0E2-AS1	ATP6V0E2 antisense RNA 1	168513	0.03
chr7_1177432_1177637	0.22	C7orf50	chromosome 7 open reading frame 50	342	0.83
chr6_127587718_127587944	0.22	RNF146	ring finger protein 146	40	0.98
chr12_118499916_118500430	0.22	WSB2	WD repeat and SOCS box containing 2	42	0.98
chr10_3111439_3111730	0.22	PFKP	phosphofructokinase, platelet	765	0.76
chr7_16686358_16686839	0.22	BZW2	basic leucine zipper and W2 domains 2	778	0.52
chr2_196521999_196522280	0.22	SLC39A10	solute carrier family 39 (zinc transporter), member 10	34	0.98
chr19_58361206_58361626	0.22	ZNF587	zinc finger protein 587	188	0.89
chr19_44031024_44031309	0.22	ETHE1	ethylmalonic encephalopathy 1	187	0.87
chr1_76189629_76189967	0.22	RP4-682C21.5		102	0.69
chr17_48906674_48906825	0.22	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	5262	0.17
chr7_76179763_76179914	0.22	AC004980.7		903	0.55
chr15_69110393_69110544	0.22	ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	2757	0.31
chr2_232480061_232480212	0.22	C2orf57	chromosome 2 open reading frame 57	22561	0.15
chr11_57103479_57104011	0.22	SSRP1	structure specific recognition protein 1	394	0.71
chr19_21325116_21325348	0.22	ZNF431	zinc finger protein 431	352	0.89
chr1_116184049_116184456	0.22	VANGL1	VANGL planar cell polarity protein 1	322	0.9
chr9_35748225_35748926	0.22	RGP1	RGP1 retrograde golgi transport homolog (S. cerevisiae)	628	0.34
chr11_33060532_33060760	0.22	TCP11L1	t-complex 11, testis-specific-like 1	317	0.89
chr4_189321790_189321972	0.22	RP11-366H4.3		257348	0.02
chr5_140762259_140762453	0.21	PCDHGA7	protocadherin gamma subfamily A, 7	111	0.88
chr3_13590656_13590970	0.21	FBLN2	fibulin 2	132	0.97
chr17_18528054_18528535	0.21	CCDC144B	coiled-coil domain containing 144B (pseudogene)	466	0.74
chr6_31784437_31784624	0.21	HSPA1L	heat shock 70kDa protein 1-like	1093	0.17
chr11_8710014_8710214	0.21	ENSG00000212607	.	3128	0.13
chr11_35440658_35441040	0.21	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	53	0.75
chr10_126431828_126432166	0.21	FAM53B	family with sequence similarity 53, member B	458	0.8
chr2_62423858_62424104	0.21	B3GNT2	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	733	0.65
chr19_47365826_47365977	0.21	AP2S1	adaptor-related protein complex 2, sigma 1 subunit	11652	0.17
chr1_19277426_19277605	0.21	IFFO2	intermediate filament family orphan 2	4677	0.22
chr4_39460235_39460455	0.21	RPL9	ribosomal protein L9	163	0.64
chr1_1656054_1656334	0.21	CDK11A	cyclin-dependent kinase 11A	428	0.74
chr17_65983_66134	0.21	DOC2B	double C2-like domains, beta	34631	0.16
chr18_21243108_21243324	0.21	ANKRD29	ankyrin repeat domain 29	367	0.88

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.2	0.5	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.1	0.3	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	0.3	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.3	GO:0072110	glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0090192	regulation of glomerulus development(GO:0090192)
0.1	0.3	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.2	GO:0072109	glomerular mesangium development(GO:0072109)
0.1	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.7	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.1	0.2	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.4	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.2	GO:0007144	female meiosis I(GO:0007144)
0.1	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.3	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.2	GO:0061316	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) canonical Wnt signaling pathway involved in heart development(GO:0061316) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	0.4	GO:0097435	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.1	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.2	GO:0035751	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.1	0.2	GO:0034629	cellular protein complex localization(GO:0034629)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.5	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.2	GO:0060157	urinary bladder development(GO:0060157)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.2	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	0.2	GO:0046958	nonassociative learning(GO:0046958)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.2	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.2	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.1	0.2	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.3	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.3	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.2	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0046548	retinal rod cell development(GO:0046548)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0000462	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.2	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.2	GO:0021561	facial nerve development(GO:0021561)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.5	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.5	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0	0.2	GO:0009129	pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.4	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0030859	polarized epithelial cell differentiation(GO:0030859)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.2	GO:1904376	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.2	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.2	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0042424	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0014808	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0014056	acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.2	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.4	GO:0000045	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0046100	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.1	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:1903313	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.2	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.0	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.1	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.4	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.2	GO:0006228	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.3	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0003356	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.4	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0010842	retina layer formation(GO:0010842)
0.0	0.1	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911) negative regulation of cell killing(GO:0031342)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.0	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0033145	positive regulation of intracellular steroid hormone receptor signaling pathway(GO:0033145)
0.0	0.2	GO:0050650	chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0	0.2	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.0	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0021898	commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0031935	regulation of chromatin silencing(GO:0031935)
0.0	0.3	GO:0007030	Golgi organization(GO:0007030)
0.0	0.0	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0019060	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.2	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0	0.0	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.3	GO:0051693	actin filament capping(GO:0051693)
0.0	0.5	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0010882	regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166) adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0042976	activation of Janus kinase activity(GO:0042976)
0.0	0.1	GO:0042069	regulation of catecholamine metabolic process(GO:0042069)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.2	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.2	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.0	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.0	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.0	GO:0051024	positive regulation of immunoglobulin secretion(GO:0051024)
0.0	0.1	GO:0045843	negative regulation of striated muscle tissue development(GO:0045843)
0.0	0.3	GO:0034508	centromere complex assembly(GO:0034508)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0051322	anaphase(GO:0051322)
0.0	0.3	GO:0050684	regulation of mRNA processing(GO:0050684) regulation of mRNA metabolic process(GO:1903311)
0.0	0.0	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.1	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	1.2	GO:0006415	translational termination(GO:0006415)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0051974	negative regulation of telomerase activity(GO:0051974)
0.0	0.0	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.1	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.9	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.0	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.2	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.0	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0090494	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.1	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.2	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.2	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0002579	positive regulation of antigen processing and presentation(GO:0002579) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.1	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	0.1	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.0	GO:0010713	negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966) negative regulation of multicellular organismal metabolic process(GO:0044252)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.0	GO:0032648	regulation of interferon-beta production(GO:0032648)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0070431	cytoplasmic pattern recognition receptor signaling pathway(GO:0002753) nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.0	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0071459	protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:1902743	regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.0	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.2	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.2	GO:0006490	dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	0.3	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.4	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.1	0.4	GO:0051233	spindle midzone(GO:0051233)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0005588	collagen type V trimer(GO:0005588)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0	0.6	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.2	GO:0000791	euchromatin(GO:0000791)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0043230	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.5	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.2	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	0.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0044217	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.0	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0005883	neurofilament(GO:0005883)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	1.0	GO:0000786	nucleosome(GO:0000786)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.3	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.6	GO:0022626	cytosolic ribosome(GO:0022626)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.0	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.7	GO:0000922	spindle pole(GO:0000922)
0.0	0.0	GO:0071438	invadopodium membrane(GO:0071438)
0.0	0.2	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.0	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.0	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	1.3	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.0	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0043204	perikaryon(GO:0043204)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.5	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.5	GO:0016605	PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004849	uridine kinase activity(GO:0004849)
0.1	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.2	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1	0.2	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	0.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.1	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	0.7	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	0.2	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.2	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.2	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.2	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.3	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.5	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.9	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.0	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.2	GO:0004112	cyclic-nucleotide phosphodiesterase activity(GO:0004112)
0.0	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.3	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.3	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.0	GO:0070061	fructose binding(GO:0070061)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.2	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.3	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	1.2	GO:0008017	microtubule binding(GO:0008017)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.2	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.3	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005436	sodium:phosphate symporter activity(GO:0005436)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.7	GO:0003899	DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.2	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.0	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.0	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.0	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.3	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.4	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.0	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.2	GO:0043022	ribosome binding(GO:0043022)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0046030	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.2	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.0	GO:0032407	MutSalpha complex binding(GO:0032407)
0.0	0.1	GO:0003678	DNA helicase activity(GO:0003678)
0.0	1.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.2	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0030983	mismatched DNA binding(GO:0030983)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0070888	E-box binding(GO:0070888)
0.0	0.3	GO:0004402	histone acetyltransferase activity(GO:0004402)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.0	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.4	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.4	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.5	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.7	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	PID FOXO PATHWAY	FoxO family signaling
0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.3	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.4	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.6	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.7	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.6	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.4	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.6	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	1.0	REACTOME KERATAN SULFATE KERATIN METABOLISM	Genes involved in Keratan sulfate/keratin metabolism
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.6	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.1	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	1.3	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.2	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.7	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.4	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.1	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.2	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.0	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.3	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.0	0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.4	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.1	REACTOME SIGNALLING TO ERKS	Genes involved in Signalling to ERKs
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.9	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	0.1	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1

Results for GCM2

Z-value: 1.64

Motif logo

Transcription factors associated with GCM2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the GCM2 motif across conditions

Conditions sorted by the z-value of the GCM2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GCM2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: