Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GFI1B

Z-value: 3.91

Motif logo

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Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
ENSG00000165702.8 GFI1B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
GFI1Bchr9_135878087_135878238161190.118013-0.732.4e-02Click!
GFI1Bchr9_135869581_13586973276130.130711-0.703.5e-02Click!
GFI1Bchr9_135858887_13585903830810.167435-0.703.6e-02Click!
GFI1Bchr9_135855020_1358551719970.421283-0.694.0e-02Click!
GFI1Bchr9_135857688_13585788236870.152893-0.636.6e-02Click!

Activity of the GFI1B motif across conditions

Conditions sorted by the z-value of the GFI1B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_21558261_21558438 1.81 MIR31HG
MIR31 host gene (non-protein coding)
1319
0.44
chr7_42645149_42645379 1.81 C7orf25
chromosome 7 open reading frame 25
306245
0.01
chr12_59312903_59313092 1.72 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
330
0.87
chr4_187646262_187646501 1.56 FAT1
FAT atypical cadherin 1
1372
0.58
chr6_86160997_86161214 1.45 NT5E
5'-nucleotidase, ecto (CD73)
1278
0.58
chrX_53078377_53078712 1.45 GPR173
G protein-coupled receptor 173
79
0.97
chr3_29323996_29324173 1.45 RBMS3
RNA binding motif, single stranded interacting protein 3
977
0.62
chr22_46478545_46478698 1.44 FLJ27365
hsa-mir-4763
2429
0.15
chr3_149801405_149801614 1.40 ENSG00000243321
.
5891
0.21
chr3_114119404_114119777 1.39 ZBTB20-AS1
ZBTB20 antisense RNA 1
13074
0.21
chr21_17796431_17796623 1.36 ENSG00000207638
.
114882
0.06
chr2_216301575_216301809 1.34 AC012462.1

716
0.48
chr5_59783926_59784223 1.33 PDE4D
phosphodiesterase 4D, cAMP-specific
171
0.97
chr3_150066038_150066370 1.33 TSC22D2
TSC22 domain family, member 2
59918
0.14
chr12_59265576_59265746 1.32 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
2693
0.36
chr3_149373565_149373716 1.31 WWTR1-AS1
WWTR1 antisense RNA 1
1167
0.38
chr1_163038601_163039117 1.29 RGS4
regulator of G-protein signaling 4
76
0.98
chr7_55086291_55086580 1.27 EGFR
epidermal growth factor receptor
279
0.95
chr11_89224254_89224444 1.26 NOX4
NADPH oxidase 4
50
0.99
chrX_103381032_103381192 1.24 SLC25A53
solute carrier family 25, member 53
20596
0.16
chr10_10953626_10954104 1.23 CELF2
CUGBP, Elav-like family member 2
93394
0.08
chr1_185704958_185705157 1.22 HMCN1
hemicentin 1
1374
0.57
chr15_63337269_63337696 1.21 TPM1
tropomyosin 1 (alpha)
1507
0.37
chr5_15500207_15500358 1.21 FBXL7
F-box and leucine-rich repeat protein 7
23
0.99
chr1_32168262_32168423 1.21 COL16A1
collagen, type XVI, alpha 1
1426
0.34
chr12_30949792_30950072 1.20 CAPRIN2
caprin family member 2
42047
0.19
chr11_12697523_12698245 1.19 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
834
0.75
chr14_102302430_102302761 1.18 CTD-2017C7.1

3273
0.21
chr1_35754106_35754533 1.17 ENSG00000240374
.
3780
0.18
chr5_122493680_122494140 1.17 AC106786.1

67916
0.1
chr17_81067326_81067613 1.17 METRNL
meteorin, glial cell differentiation regulator-like
15475
0.24
chr11_121975812_121976123 1.14 RP11-166D19.1

90
0.96
chr5_121411093_121411244 1.13 LOX
lysyl oxidase
2812
0.31
chr4_20257540_20257840 1.13 SLIT2
slit homolog 2 (Drosophila)
1147
0.67
chr4_4854789_4855427 1.10 MSX1
msh homeobox 1
6285
0.29
chr5_170024900_170025159 1.10 CTC-265N9.1

83412
0.09
chr15_86163319_86163521 1.10 RP11-815J21.3

7500
0.15
chr5_155754238_155754771 1.09 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
737
0.81
chr5_150325496_150325780 1.08 ZNF300P1
zinc finger protein 300 pseudogene 1
213
0.94
chr3_149373320_149373471 1.08 WWTR1-AS1
WWTR1 antisense RNA 1
1412
0.33
chr12_76653631_76654077 1.08 ENSG00000223273
.
55677
0.14
chr10_52752095_52752246 1.06 PRKG1
protein kinase, cGMP-dependent, type I
1052
0.64
chr12_114843211_114843442 1.05 TBX5
T-box 5
563
0.78
chr10_35105469_35105702 1.05 PARD3-AS1
PARD3 antisense RNA 1
890
0.52
chr1_7130330_7130574 1.05 RP11-334N17.1

56113
0.15
chr12_13350846_13351208 1.05 EMP1
epithelial membrane protein 1
1307
0.55
chr16_56667294_56667600 1.04 MT1M
metallothionein 1M
828
0.29
chr3_49169788_49170138 1.04 LAMB2
laminin, beta 2 (laminin S)
490
0.65
chr2_23819189_23819442 1.04 KLHL29
kelch-like family member 29
45947
0.18
chr1_98514742_98514981 1.04 ENSG00000225206
.
3134
0.4
chr1_39572596_39572941 1.04 MACF1
microtubule-actin crosslinking factor 1
1685
0.35
chr11_12399801_12400294 1.03 PARVA
parvin, alpha
901
0.64
chr21_17652326_17652785 1.02 ENSG00000201025
.
4534
0.36
chr7_54956069_54956673 1.02 ENSG00000252054
.
22860
0.25
chr3_100711576_100712203 1.00 ABI3BP
ABI family, member 3 (NESH) binding protein
408
0.89
chr15_33011706_33011883 1.00 GREM1
gremlin 1, DAN family BMP antagonist
1589
0.4
chr3_64209595_64209746 0.97 PRICKLE2
prickle homolog 2 (Drosophila)
1461
0.46
chr9_100069234_100069583 0.97 CCDC180
coiled-coil domain containing 180
533
0.83
chr2_235861878_235862318 0.97 SH3BP4
SH3-domain binding protein 4
1378
0.62
chr5_31193803_31195028 0.95 CDH6
cadherin 6, type 2, K-cadherin (fetal kidney)
558
0.85
chr4_138455145_138455297 0.95 PCDH18
protocadherin 18
1573
0.58
chr13_93879365_93880233 0.95 GPC6
glypican 6
704
0.82
chr5_66254826_66254999 0.94 MAST4
microtubule associated serine/threonine kinase family member 4
96
0.98
chr17_48132523_48133080 0.94 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
538
0.71
chr4_111558170_111558322 0.94 PITX2
paired-like homeodomain 2
64
0.99
chr2_238035569_238035720 0.94 COPS8
COP9 signalosome subunit 8
41058
0.15
chr5_141595832_141596208 0.93 SPRY4
sprouty homolog 4 (Drosophila)
107727
0.06
chr10_33622034_33622426 0.92 NRP1
neuropilin 1
1080
0.63
chr3_66139685_66140118 0.92 SLC25A26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
20616
0.25
chr4_169554219_169554371 0.92 PALLD
palladin, cytoskeletal associated protein
1527
0.43
chr2_238116736_238116905 0.92 AC112715.2
Uncharacterized protein
48914
0.16
chr5_6732608_6732814 0.92 PAPD7
PAP associated domain containing 7
17966
0.25
chr7_27152802_27153012 0.92 HOXA3
homeobox A3
557
0.38
chr3_125321989_125322196 0.91 OSBPL11
oxysterol binding protein-like 11
8158
0.22
chr14_50490583_50491073 0.91 C14orf182
chromosome 14 open reading frame 182
16590
0.16
chr3_149356078_149356269 0.91 WWTR1-IT1
WWTR1 intronic transcript 1 (non-protein coding)
11798
0.17
chr18_77906051_77906465 0.90 AC139100.2
Uncharacterized protein
326
0.89
chr17_42906288_42907233 0.90 GJC1
gap junction protein, gamma 1, 45kDa
302
0.85
chr21_17442706_17442989 0.90 ENSG00000252273
.
35018
0.24
chr7_42533422_42533764 0.89 GLI3
GLI family zinc finger 3
256935
0.02
chr1_18192837_18193085 0.89 ACTL8
actin-like 8
111153
0.07
chr4_183064801_183065567 0.89 AC108142.1

143
0.83
chr11_114237888_114238168 0.89 RP11-64D24.2

10735
0.15
chr5_36608256_36608472 0.89 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
67
0.99
chr17_36902558_36902709 0.89 PCGF2
polycomb group ring finger 2
248
0.78
chr13_33779104_33779430 0.89 STARD13
StAR-related lipid transfer (START) domain containing 13
876
0.67
chr15_56204998_56205389 0.89 NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
2659
0.34
chr17_38255735_38256962 0.88 NR1D1
nuclear receptor subfamily 1, group D, member 1
630
0.6
chr11_102981029_102981283 0.88 DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
852
0.65
chr1_177139870_177140730 0.88 BRINP2
bone morphogenetic protein/retinoic acid inducible neural-specific 2
333
0.89
chr11_46307450_46307608 0.87 CREB3L1
cAMP responsive element binding protein 3-like 1
8301
0.18
chr2_17721828_17722425 0.87 VSNL1
visinin-like 1
163
0.97
chr5_92943123_92943644 0.87 ENSG00000251725
.
13111
0.2
chr11_75274364_75274515 0.87 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
28
0.97
chr5_110406345_110406728 0.86 TSLP
thymic stromal lymphopoietin
776
0.67
chr2_219472134_219472377 0.86 PLCD4
phospholipase C, delta 4
233
0.86
chr2_19221096_19221271 0.86 ENSG00000266738
.
327007
0.01
chr18_53087965_53088125 0.85 TCF4
transcription factor 4
1541
0.45
chr1_229524899_229525061 0.85 ENSG00000252506
.
6105
0.16
chr12_27709290_27709441 0.85 PPFIBP1
PTPRF interacting protein, binding protein 1 (liprin beta 1)
18309
0.22
chr9_2838300_2838770 0.85 KIAA0020
KIAA0020
5706
0.3
chr17_15312712_15312879 0.84 ENSG00000239888
.
1094
0.54
chr2_230993548_230993699 0.84 AC009950.2

3597
0.26
chr20_59826813_59827194 0.84 CDH4
cadherin 4, type 1, R-cadherin (retinal)
479
0.9
chr11_101981627_101982145 0.84 YAP1
Yes-associated protein 1
306
0.88
chr17_15209957_15210211 0.84 ENSG00000200437
.
4578
0.19
chr5_81341593_81341802 0.84 ATG10-AS1
ATG10 antisense RNA 1
27824
0.16
chr8_87051491_87051698 0.83 PSKH2
protein serine kinase H2
30332
0.19
chr13_107186025_107186496 0.83 EFNB2
ephrin-B2
1202
0.59
chr19_18497753_18498116 0.83 ENSG00000264175
.
562
0.48
chr2_238578863_238579079 0.83 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
21817
0.19
chr2_19202600_19202769 0.83 ENSG00000266738
.
345506
0.01
chr9_684288_685148 0.83 RP11-130C19.3

837
0.67
chr3_73776409_73776793 0.83 PDZRN3
PDZ domain containing ring finger 3
102510
0.07
chr18_56531788_56532358 0.83 ZNF532
zinc finger protein 532
20
0.98
chr10_49812568_49813319 0.83 ARHGAP22
Rho GTPase activating protein 22
54
0.98
chr10_102278895_102279852 0.83 SEC31B
SEC31 homolog B (S. cerevisiae)
218
0.92
chr1_63154994_63155145 0.82 RP11-230B22.1

916
0.45
chr1_172109224_172109375 0.82 ENSG00000207949
.
1252
0.44
chr11_94182402_94182553 0.81 ENSG00000221230
.
17269
0.13
chr9_95298144_95298315 0.81 ECM2
extracellular matrix protein 2, female organ and adipocyte specific
25
0.98
chr4_187648403_187648661 0.81 FAT1
FAT atypical cadherin 1
656
0.82
chr14_80678181_80678374 0.80 DIO2
deiodinase, iodothyronine, type II
244
0.75
chr13_75150084_75150294 0.80 LINC00381
long intergenic non-protein coding RNA 381
156879
0.04
chr6_138427325_138427625 0.80 PERP
PERP, TP53 apoptosis effector
1173
0.59
chr17_37856067_37857084 0.80 ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
242
0.86
chr6_100909413_100909564 0.79 SIM1
single-minded family bHLH transcription factor 1
2065
0.42
chr20_57233106_57233257 0.79 STX16
syntaxin 16
6118
0.17
chr2_18157972_18158481 0.79 ENSG00000212455
.
63773
0.13
chr20_10579322_10579500 0.79 JAG1
jagged 1
63743
0.13
chr19_50193963_50194180 0.78 CTB-33G10.6

241
0.5
chr13_33803329_33803516 0.78 STARD13
StAR-related lipid transfer (START) domain containing 13
23279
0.2
chr3_112355873_112356097 0.78 CCDC80
coiled-coil domain containing 80
959
0.65
chr2_69244565_69244720 0.78 ANTXR1
anthrax toxin receptor 1
4113
0.25
chr15_91006991_91007196 0.78 RP11-154B12.3

65980
0.08
chr4_16900577_16901013 0.78 LDB2
LIM domain binding 2
363
0.93
chr2_176995490_176995715 0.78 HOXD8
homeobox D8
517
0.55
chr1_220701624_220702485 0.78 MARK1
MAP/microtubule affinity-regulating kinase 1
155
0.97
chr9_73483733_73483949 0.77 TRPM3
transient receptor potential cation channel, subfamily M, member 3
98
0.98
chr6_137442626_137442884 0.77 IL22RA2
interleukin 22 receptor, alpha 2
52030
0.14
chr7_27217830_27218176 0.77 RP1-170O19.20
Uncharacterized protein
1629
0.13
chr4_26577939_26578090 0.77 TBC1D19
TBC1 domain family, member 19
45
0.98
chr2_134432019_134432170 0.76 ENSG00000200708
.
78432
0.11
chr2_56412283_56412467 0.75 AC007743.1

327
0.83
chr8_119344627_119344778 0.75 AC023590.1
Uncharacterized protein
50221
0.19
chr5_92919468_92919846 0.75 NR2F1
nuclear receptor subfamily 2, group F, member 1
614
0.69
chr7_134474351_134474502 0.75 CALD1
caldesmon 1
9997
0.29
chr17_79609293_79609648 0.75 TSPAN10
tetraspanin 10
121
0.91
chr13_102151652_102151813 0.75 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
9429
0.3
chr3_110132950_110133243 0.75 ENSG00000221206
.
137716
0.05
chr18_57385985_57386276 0.75 CCBE1
collagen and calcium binding EGF domains 1
21518
0.16
chr1_210405641_210405792 0.75 SERTAD4
SERTA domain containing 4
428
0.6
chr12_76271592_76272084 0.75 ENSG00000243420
.
80072
0.1
chr9_86875979_86876265 0.74 RP11-380F14.2

17012
0.26
chr3_100784704_100784898 0.74 ABI3BP
ABI family, member 3 (NESH) binding protein
72442
0.11
chr11_8889856_8890095 0.74 ST5
suppression of tumorigenicity 5
2489
0.19
chr17_13965501_13965785 0.74 ENSG00000236088
.
7132
0.24
chr1_94159203_94159501 0.73 BCAR3
breast cancer anti-estrogen resistance 3
11967
0.24
chr6_150173382_150173533 0.73 RP11-350J20.12

141
0.93
chr17_13266074_13266343 0.73 ENSG00000266115
.
137437
0.05
chr6_148664824_148664993 0.73 SASH1
SAM and SH3 domain containing 1
1179
0.59
chr2_175854784_175854957 0.73 ENSG00000201425
.
12339
0.15
chr10_33626258_33626516 0.73 NRP1
neuropilin 1
1197
0.6
chr6_133890397_133891036 0.73 RP3-323P13.2

57850
0.15
chr1_240760211_240760638 0.73 RP11-467I20.6

6376
0.21
chr4_52903753_52904199 0.73 SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
449
0.84
chr17_46651973_46652199 0.73 HOXB3
homeobox B3
237
0.8
chr15_74222319_74222668 0.72 LOXL1-AS1
LOXL1 antisense RNA 1
1904
0.26
chr12_26112779_26113361 0.72 RASSF8-AS1
RASSF8 atnisense RNA 1
372
0.8
chr3_147648289_147648638 0.72 ENSG00000221431
.
19175
0.29
chr1_240258821_240259228 0.72 FMN2
formin 2
3844
0.31
chr5_40915264_40915466 0.72 ENSG00000253098
.
4135
0.21
chr6_31082599_31082878 0.72 PSORS1C1
psoriasis susceptibility 1 candidate 1
130
0.91
chr10_48336328_48336544 0.72 ZNF488
zinc finger protein 488
18588
0.14
chr7_41926126_41926481 0.71 AC005027.3

181370
0.03
chr1_245255499_245255650 0.71 EFCAB2
EF-hand calcium binding domain 2
8816
0.18
chr1_97610415_97610576 0.71 DPYD-AS1
DPYD antisense RNA 1
49016
0.19
chr1_78005180_78005370 0.71 AK5
adenylate kinase 5
7483
0.25
chr19_49561050_49561269 0.71 CGB7
chorionic gonadotropin, beta polypeptide 7
151
0.85
chr12_85305306_85305778 0.71 SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
261
0.96
chr4_151062450_151062706 0.71 DCLK2
doublecortin-like kinase 2
62398
0.13
chr4_123751095_123751246 0.71 ENSG00000253069
.
3001
0.24
chr1_8433877_8434267 0.71 RERE
arginine-glutamic acid dipeptide (RE) repeats
9174
0.19
chr14_29705884_29706116 0.71 ENSG00000257522
.
141862
0.05
chrX_100740463_100741131 0.71 ARMCX4
armadillo repeat containing, X-linked 4
2234
0.26
chr2_191511664_191511958 0.71 NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
339
0.9
chr5_56834430_56834632 0.70 ACTBL2
actin, beta-like 2
55895
0.13
chr10_95240803_95240954 0.70 MYOF
myoferlin
1073
0.51
chr13_113832243_113832413 0.70 RP11-98F14.11

12831
0.12
chr6_117852473_117852851 0.70 DCBLD1
discoidin, CUB and LCCL domain containing 1
48837
0.12
chr2_24398374_24398902 0.70 FAM228A
family with sequence similarity 228, member A
284
0.75
chr5_91977319_91977616 0.70 ENSG00000221810
.
75753
0.13
chr19_16179581_16179939 0.69 TPM4
tropomyosin 4
1250
0.44
chr5_34658039_34658190 0.69 CTD-2024P10.1

759
0.56
chr4_55945978_55946129 0.69 ENSG00000244034
.
16151
0.17
chr3_13421009_13421370 0.69 NUP210
nucleoporin 210kDa
40620
0.18
chr3_134125279_134125630 0.69 ENSG00000221313
.
3528
0.24
chr6_150218005_150218162 0.69 RAET1E
retinoic acid early transcript 1E
888
0.45
chr4_81195528_81195918 0.69 FGF5
fibroblast growth factor 5
7930
0.26
chr10_17275800_17275972 0.69 RP11-124N14.3

946
0.49

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of GFI1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0070141 response to UV-A(GO:0070141)
0.4 1.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4 1.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4 1.2 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.4 1.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.4 1.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.4 1.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.3 0.3 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.3 1.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 1.0 GO:0060242 contact inhibition(GO:0060242)
0.3 0.9 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.3 1.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.3 0.8 GO:0010996 response to auditory stimulus(GO:0010996)
0.3 1.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.3 1.0 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2 0.7 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.9 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.6 GO:2000188 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.2 1.2 GO:0016264 gap junction assembly(GO:0016264)
0.2 0.4 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 0.8 GO:0008218 bioluminescence(GO:0008218)
0.2 0.8 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.6 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2 0.4 GO:0010159 specification of organ position(GO:0010159)
0.2 0.5 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.2 0.9 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.5 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 0.5 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.7 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.4 GO:0060502 epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.5 GO:0035329 hippo signaling(GO:0035329)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.5 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.3 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.8 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.6 GO:0070474 uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.9 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.7 GO:0055091 phospholipid homeostasis(GO:0055091)
0.1 0.4 GO:0008215 spermine metabolic process(GO:0008215)
0.1 3.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.4 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.3 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.7 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1 1.2 GO:0001660 fever generation(GO:0001660)
0.1 0.3 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1 0.5 GO:0002068 glandular epithelial cell development(GO:0002068)
0.1 0.3 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.4 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.1 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1 0.3 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.3 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.7 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.2 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.3 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.4 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 0.1 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.6 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0051182 coenzyme transport(GO:0051182)
0.1 1.3 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.1 GO:0071294 cellular response to zinc ion(GO:0071294)
0.1 0.2 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.6 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.2 GO:0007350 blastoderm segmentation(GO:0007350)
0.1 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.2 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 0.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.1 0.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0060013 righting reflex(GO:0060013)
0.1 0.4 GO:0001945 lymph vessel development(GO:0001945)
0.1 1.0 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 0.7 GO:0043030 regulation of macrophage activation(GO:0043030)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.3 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.1 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.2 GO:0010842 retina layer formation(GO:0010842)
0.1 0.5 GO:0031000 response to caffeine(GO:0031000)
0.1 0.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.3 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.1 0.2 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 0.3 GO:0018126 protein hydroxylation(GO:0018126)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.6 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 0.1 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.1 GO:0060039 pericardium development(GO:0060039)
0.1 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.9 GO:0008038 neuron recognition(GO:0008038)
0.1 0.2 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1 0.5 GO:0007567 parturition(GO:0007567)
0.1 0.2 GO:0009648 photoperiodism(GO:0009648)
0.1 0.2 GO:0030488 tRNA methylation(GO:0030488)
0.1 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.1 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.1 1.1 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.2 GO:0060539 diaphragm development(GO:0060539)
0.1 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.1 GO:0021591 ventricular system development(GO:0021591)
0.1 0.1 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.1 0.4 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.1 0.2 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 1.1 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 1.0 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:0035088 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.5 GO:0031103 axon regeneration(GO:0031103)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 2.1 GO:0001764 neuron migration(GO:0001764)
0.0 0.9 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.0 0.1 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.4 GO:0043113 receptor clustering(GO:0043113)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0 0.2 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0 0.1 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.4 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.8 GO:0007340 acrosome reaction(GO:0007340)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0060296 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.4 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765)
0.0 0.0 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0060179 male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0007492 endoderm development(GO:0007492)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.3 GO:0051319 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.2 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.8 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.0 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.0 0.6 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.4 GO:0002544 chronic inflammatory response(GO:0002544)
0.0 0.0 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.3 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0010092 specification of organ identity(GO:0010092)
0.0 0.3 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.3 GO:0014075 response to amine(GO:0014075)
0.0 0.0 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 0.1 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:2000171 negative regulation of dendrite morphogenesis(GO:0050774) negative regulation of dendrite development(GO:2000171)
0.0 1.0 GO:0007569 cell aging(GO:0007569)
0.0 0.2 GO:0009437 amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.6 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.2 GO:0006000 fructose metabolic process(GO:0006000)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0048319 axial mesoderm development(GO:0048318) axial mesoderm morphogenesis(GO:0048319)
0.0 0.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0043502 regulation of muscle adaptation(GO:0043502)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.2 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.2 GO:0090280 positive regulation of calcium ion import(GO:0090280)
0.0 0.3 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.0 GO:0044268 regulation of angiotensin levels in blood(GO:0002002) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268) regulation of angiotensin metabolic process(GO:0060177)
0.0 0.0 GO:0060442 branching involved in prostate gland morphogenesis(GO:0060442)
0.0 0.0 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.0 GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.0 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.0 0.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.2 GO:0060828 regulation of canonical Wnt signaling pathway(GO:0060828)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.0 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0009414 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:1902749 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.4 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.2 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0051503 purine nucleotide transport(GO:0015865) adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.9 GO:0009408 response to heat(GO:0009408)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0072111 cell proliferation involved in kidney development(GO:0072111)
0.0 0.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.2 GO:0051058 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 0.4 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0060065 uterus development(GO:0060065)
0.0 0.0 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.2 GO:0072164 ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 0.0 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.3 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0010001 glial cell differentiation(GO:0010001)
0.0 0.1 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0043650 dicarboxylic acid biosynthetic process(GO:0043650)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.0 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.0 GO:0046015 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.0 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.0 GO:0015870 acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 1.5 GO:0007517 muscle organ development(GO:0007517)
0.0 0.1 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.0 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0051149 positive regulation of muscle cell differentiation(GO:0051149)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0048806 genitalia development(GO:0048806)
0.0 0.0 GO:0072112 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.0 0.3 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.3 GO:0042472 inner ear morphogenesis(GO:0042472)
0.0 0.1 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0019915 lipid storage(GO:0019915)
0.0 0.0 GO:0048087 positive regulation of developmental pigmentation(GO:0048087)
0.0 0.0 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 1.8 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.1 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.0 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0014015 positive regulation of gliogenesis(GO:0014015)
0.0 0.0 GO:0002858 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.0 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.0 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0007343 egg activation(GO:0007343)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.0 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.0 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.0 GO:0060767 epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.7 GO:0005614 interstitial matrix(GO:0005614)
0.3 1.8 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.7 GO:0043260 laminin-11 complex(GO:0043260)
0.2 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 0.5 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.2 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.7 GO:0071437 invadopodium(GO:0071437)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.4 GO:0070852 cell body fiber(GO:0070852)
0.1 1.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.2 GO:0043205 fibril(GO:0043205)
0.1 0.7 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.6 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.1 GO:0016342 catenin complex(GO:0016342)
0.1 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0002102 podosome(GO:0002102)
0.1 0.7 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.0 GO:0005811 lipid particle(GO:0005811)
0.1 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 4.6 GO:0005925 focal adhesion(GO:0005925)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 2.8 GO:0030426 growth cone(GO:0030426)
0.0 0.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 2.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.9 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 4.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.9 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 7.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.5 GO:0030118 clathrin coat(GO:0030118)
0.0 0.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.2 GO:0032589 neuron projection membrane(GO:0032589)
0.0 1.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 0.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0032806 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.5 1.4 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3 1.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.3 1.0 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.3 1.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 0.9 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 0.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.2 1.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.2 GO:0043559 insulin binding(GO:0043559)
0.2 1.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 0.7 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 1.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 1.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.4 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 0.8 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 0.8 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 3.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 0.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.3 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.1 0.2 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.8 GO:0030553 cGMP binding(GO:0030553)
0.1 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.5 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.2 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.2 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.9 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.3 GO:0001848 complement binding(GO:0001848)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.1 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0009374 biotin binding(GO:0009374)
0.0 1.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 1.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0016918 retinal binding(GO:0016918)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 1.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.3 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.2 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 8.2 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.3 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.8 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 2.0 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0016595 glutamate binding(GO:0016595)
0.0 0.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0030172 troponin C binding(GO:0030172)
0.0 0.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.0 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.3 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 1.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.0 GO:0055102 lipase inhibitor activity(GO:0055102)
0.0 0.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 5.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.0 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.0 GO:0030546 receptor activator activity(GO:0030546)
0.0 0.0 GO:0016413 O-acetyltransferase activity(GO:0016413)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.0 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 5.7 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 1.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.1 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 5.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 0.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID FGF PATHWAY FGF signaling pathway
0.0 3.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 0.2 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.2 3.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 3.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.5 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.1 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.0 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.8 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.0 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.2 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME GABA RECEPTOR ACTIVATION Genes involved in GABA receptor activation
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport