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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for GFI1B

Z-value: 3.91

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Transcription factors associated with GFI1B

Gene Symbol	Gene ID	Gene Info
GFI1B Ensembl NCBI GeneCards UniProt	ENSG00000165702.8	growth factor independent 1B transcriptional repressor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr9_135878087_135878238	GFI1B	16119	0.118013	-0.73	2.4e-02	Click!
chr9_135869581_135869732	GFI1B	7613	0.130711	-0.70	3.5e-02	Click!
chr9_135858887_135859038	GFI1B	3081	0.167435	-0.70	3.6e-02	Click!
chr9_135855020_135855171	GFI1B	997	0.421283	-0.69	4.0e-02	Click!
chr9_135857688_135857882	GFI1B	3687	0.152893	-0.63	6.6e-02	Click!

Activity of the GFI1B motif across conditions

Conditions sorted by the z-value of the GFI1B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_21558261_21558438	1.81	MIR31HG	MIR31 host gene (non-protein coding)	1319	0.44
chr7_42645149_42645379	1.81	C7orf25	chromosome 7 open reading frame 25	306245	0.01
chr12_59312903_59313092	1.72	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	330	0.87
chr4_187646262_187646501	1.56	FAT1	FAT atypical cadherin 1	1372	0.58
chr6_86160997_86161214	1.45	NT5E	5'-nucleotidase, ecto (CD73)	1278	0.58
chrX_53078377_53078712	1.45	GPR173	G protein-coupled receptor 173	79	0.97
chr3_29323996_29324173	1.45	RBMS3	RNA binding motif, single stranded interacting protein 3	977	0.62
chr22_46478545_46478698	1.44	FLJ27365	hsa-mir-4763	2429	0.15
chr3_149801405_149801614	1.40	ENSG00000243321	.	5891	0.21
chr3_114119404_114119777	1.39	ZBTB20-AS1	ZBTB20 antisense RNA 1	13074	0.21
chr21_17796431_17796623	1.36	ENSG00000207638	.	114882	0.06
chr2_216301575_216301809	1.34	AC012462.1		716	0.48
chr5_59783926_59784223	1.33	PDE4D	phosphodiesterase 4D, cAMP-specific	171	0.97
chr3_150066038_150066370	1.33	TSC22D2	TSC22 domain family, member 2	59918	0.14
chr12_59265576_59265746	1.32	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2693	0.36
chr3_149373565_149373716	1.31	WWTR1-AS1	WWTR1 antisense RNA 1	1167	0.38
chr1_163038601_163039117	1.29	RGS4	regulator of G-protein signaling 4	76	0.98
chr7_55086291_55086580	1.27	EGFR	epidermal growth factor receptor	279	0.95
chr11_89224254_89224444	1.26	NOX4	NADPH oxidase 4	50	0.99
chrX_103381032_103381192	1.24	SLC25A53	solute carrier family 25, member 53	20596	0.16
chr10_10953626_10954104	1.23	CELF2	CUGBP, Elav-like family member 2	93394	0.08
chr1_185704958_185705157	1.22	HMCN1	hemicentin 1	1374	0.57
chr15_63337269_63337696	1.21	TPM1	tropomyosin 1 (alpha)	1507	0.37
chr5_15500207_15500358	1.21	FBXL7	F-box and leucine-rich repeat protein 7	23	0.99
chr1_32168262_32168423	1.21	COL16A1	collagen, type XVI, alpha 1	1426	0.34
chr12_30949792_30950072	1.20	CAPRIN2	caprin family member 2	42047	0.19
chr11_12697523_12698245	1.19	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	834	0.75
chr14_102302430_102302761	1.18	CTD-2017C7.1		3273	0.21
chr1_35754106_35754533	1.17	ENSG00000240374	.	3780	0.18
chr5_122493680_122494140	1.17	AC106786.1		67916	0.1
chr17_81067326_81067613	1.17	METRNL	meteorin, glial cell differentiation regulator-like	15475	0.24
chr11_121975812_121976123	1.14	RP11-166D19.1		90	0.96
chr5_121411093_121411244	1.13	LOX	lysyl oxidase	2812	0.31
chr4_20257540_20257840	1.13	SLIT2	slit homolog 2 (Drosophila)	1147	0.67
chr4_4854789_4855427	1.10	MSX1	msh homeobox 1	6285	0.29
chr5_170024900_170025159	1.10	CTC-265N9.1		83412	0.09
chr15_86163319_86163521	1.10	RP11-815J21.3		7500	0.15
chr5_155754238_155754771	1.09	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	737	0.81
chr5_150325496_150325780	1.08	ZNF300P1	zinc finger protein 300 pseudogene 1	213	0.94
chr3_149373320_149373471	1.08	WWTR1-AS1	WWTR1 antisense RNA 1	1412	0.33
chr12_76653631_76654077	1.08	ENSG00000223273	.	55677	0.14
chr10_52752095_52752246	1.06	PRKG1	protein kinase, cGMP-dependent, type I	1052	0.64
chr12_114843211_114843442	1.05	TBX5	T-box 5	563	0.78
chr10_35105469_35105702	1.05	PARD3-AS1	PARD3 antisense RNA 1	890	0.52
chr1_7130330_7130574	1.05	RP11-334N17.1		56113	0.15
chr12_13350846_13351208	1.05	EMP1	epithelial membrane protein 1	1307	0.55
chr16_56667294_56667600	1.04	MT1M	metallothionein 1M	828	0.29
chr3_49169788_49170138	1.04	LAMB2	laminin, beta 2 (laminin S)	490	0.65
chr2_23819189_23819442	1.04	KLHL29	kelch-like family member 29	45947	0.18
chr1_98514742_98514981	1.04	ENSG00000225206	.	3134	0.4
chr1_39572596_39572941	1.04	MACF1	microtubule-actin crosslinking factor 1	1685	0.35
chr11_12399801_12400294	1.03	PARVA	parvin, alpha	901	0.64
chr21_17652326_17652785	1.02	ENSG00000201025	.	4534	0.36
chr7_54956069_54956673	1.02	ENSG00000252054	.	22860	0.25
chr3_100711576_100712203	1.00	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr15_33011706_33011883	1.00	GREM1	gremlin 1, DAN family BMP antagonist	1589	0.4
chr3_64209595_64209746	0.97	PRICKLE2	prickle homolog 2 (Drosophila)	1461	0.46
chr9_100069234_100069583	0.97	CCDC180	coiled-coil domain containing 180	533	0.83
chr2_235861878_235862318	0.97	SH3BP4	SH3-domain binding protein 4	1378	0.62
chr5_31193803_31195028	0.95	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	558	0.85
chr4_138455145_138455297	0.95	PCDH18	protocadherin 18	1573	0.58
chr13_93879365_93880233	0.95	GPC6	glypican 6	704	0.82
chr5_66254826_66254999	0.94	MAST4	microtubule associated serine/threonine kinase family member 4	96	0.98
chr17_48132523_48133080	0.94	ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	538	0.71
chr4_111558170_111558322	0.94	PITX2	paired-like homeodomain 2	64	0.99
chr2_238035569_238035720	0.94	COPS8	COP9 signalosome subunit 8	41058	0.15
chr5_141595832_141596208	0.93	SPRY4	sprouty homolog 4 (Drosophila)	107727	0.06
chr10_33622034_33622426	0.92	NRP1	neuropilin 1	1080	0.63
chr3_66139685_66140118	0.92	SLC25A26	solute carrier family 25 (S-adenosylmethionine carrier), member 26	20616	0.25
chr4_169554219_169554371	0.92	PALLD	palladin, cytoskeletal associated protein	1527	0.43
chr2_238116736_238116905	0.92	AC112715.2	Uncharacterized protein	48914	0.16
chr5_6732608_6732814	0.92	PAPD7	PAP associated domain containing 7	17966	0.25
chr7_27152802_27153012	0.92	HOXA3	homeobox A3	557	0.38
chr3_125321989_125322196	0.91	OSBPL11	oxysterol binding protein-like 11	8158	0.22
chr14_50490583_50491073	0.91	C14orf182	chromosome 14 open reading frame 182	16590	0.16
chr3_149356078_149356269	0.91	WWTR1-IT1	WWTR1 intronic transcript 1 (non-protein coding)	11798	0.17
chr18_77906051_77906465	0.90	AC139100.2	Uncharacterized protein	326	0.89
chr17_42906288_42907233	0.90	GJC1	gap junction protein, gamma 1, 45kDa	302	0.85
chr21_17442706_17442989	0.90	ENSG00000252273	.	35018	0.24
chr7_42533422_42533764	0.89	GLI3	GLI family zinc finger 3	256935	0.02
chr1_18192837_18193085	0.89	ACTL8	actin-like 8	111153	0.07
chr4_183064801_183065567	0.89	AC108142.1		143	0.83
chr11_114237888_114238168	0.89	RP11-64D24.2		10735	0.15
chr5_36608256_36608472	0.89	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	67	0.99
chr17_36902558_36902709	0.89	PCGF2	polycomb group ring finger 2	248	0.78
chr13_33779104_33779430	0.89	STARD13	StAR-related lipid transfer (START) domain containing 13	876	0.67
chr15_56204998_56205389	0.89	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	2659	0.34
chr17_38255735_38256962	0.88	NR1D1	nuclear receptor subfamily 1, group D, member 1	630	0.6
chr11_102981029_102981283	0.88	DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	852	0.65
chr1_177139870_177140730	0.88	BRINP2	bone morphogenetic protein/retinoic acid inducible neural-specific 2	333	0.89
chr11_46307450_46307608	0.87	CREB3L1	cAMP responsive element binding protein 3-like 1	8301	0.18
chr2_17721828_17722425	0.87	VSNL1	visinin-like 1	163	0.97
chr5_92943123_92943644	0.87	ENSG00000251725	.	13111	0.2
chr11_75274364_75274515	0.87	SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	28	0.97
chr5_110406345_110406728	0.86	TSLP	thymic stromal lymphopoietin	776	0.67
chr2_219472134_219472377	0.86	PLCD4	phospholipase C, delta 4	233	0.86
chr2_19221096_19221271	0.86	ENSG00000266738	.	327007	0.01
chr18_53087965_53088125	0.85	TCF4	transcription factor 4	1541	0.45
chr1_229524899_229525061	0.85	ENSG00000252506	.	6105	0.16
chr12_27709290_27709441	0.85	PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	18309	0.22
chr9_2838300_2838770	0.85	KIAA0020	KIAA0020	5706	0.3
chr17_15312712_15312879	0.84	ENSG00000239888	.	1094	0.54
chr2_230993548_230993699	0.84	AC009950.2		3597	0.26
chr20_59826813_59827194	0.84	CDH4	cadherin 4, type 1, R-cadherin (retinal)	479	0.9
chr11_101981627_101982145	0.84	YAP1	Yes-associated protein 1	306	0.88
chr17_15209957_15210211	0.84	ENSG00000200437	.	4578	0.19
chr5_81341593_81341802	0.84	ATG10-AS1	ATG10 antisense RNA 1	27824	0.16
chr8_87051491_87051698	0.83	PSKH2	protein serine kinase H2	30332	0.19
chr13_107186025_107186496	0.83	EFNB2	ephrin-B2	1202	0.59
chr19_18497753_18498116	0.83	ENSG00000264175	.	562	0.48
chr2_238578863_238579079	0.83	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	21817	0.19
chr2_19202600_19202769	0.83	ENSG00000266738	.	345506	0.01
chr9_684288_685148	0.83	RP11-130C19.3		837	0.67
chr3_73776409_73776793	0.83	PDZRN3	PDZ domain containing ring finger 3	102510	0.07
chr18_56531788_56532358	0.83	ZNF532	zinc finger protein 532	20	0.98
chr10_49812568_49813319	0.83	ARHGAP22	Rho GTPase activating protein 22	54	0.98
chr10_102278895_102279852	0.83	SEC31B	SEC31 homolog B (S. cerevisiae)	218	0.92
chr1_63154994_63155145	0.82	RP11-230B22.1		916	0.45
chr1_172109224_172109375	0.82	ENSG00000207949	.	1252	0.44
chr11_94182402_94182553	0.81	ENSG00000221230	.	17269	0.13
chr9_95298144_95298315	0.81	ECM2	extracellular matrix protein 2, female organ and adipocyte specific	25	0.98
chr4_187648403_187648661	0.81	FAT1	FAT atypical cadherin 1	656	0.82
chr14_80678181_80678374	0.80	DIO2	deiodinase, iodothyronine, type II	244	0.75
chr13_75150084_75150294	0.80	LINC00381	long intergenic non-protein coding RNA 381	156879	0.04
chr6_138427325_138427625	0.80	PERP	PERP, TP53 apoptosis effector	1173	0.59
chr17_37856067_37857084	0.80	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	242	0.86
chr6_100909413_100909564	0.79	SIM1	single-minded family bHLH transcription factor 1	2065	0.42
chr20_57233106_57233257	0.79	STX16	syntaxin 16	6118	0.17
chr2_18157972_18158481	0.79	ENSG00000212455	.	63773	0.13
chr20_10579322_10579500	0.79	JAG1	jagged 1	63743	0.13
chr19_50193963_50194180	0.78	CTB-33G10.6		241	0.5
chr13_33803329_33803516	0.78	STARD13	StAR-related lipid transfer (START) domain containing 13	23279	0.2
chr3_112355873_112356097	0.78	CCDC80	coiled-coil domain containing 80	959	0.65
chr2_69244565_69244720	0.78	ANTXR1	anthrax toxin receptor 1	4113	0.25
chr15_91006991_91007196	0.78	RP11-154B12.3		65980	0.08
chr4_16900577_16901013	0.78	LDB2	LIM domain binding 2	363	0.93
chr2_176995490_176995715	0.78	HOXD8	homeobox D8	517	0.55
chr1_220701624_220702485	0.78	MARK1	MAP/microtubule affinity-regulating kinase 1	155	0.97
chr9_73483733_73483949	0.77	TRPM3	transient receptor potential cation channel, subfamily M, member 3	98	0.98
chr6_137442626_137442884	0.77	IL22RA2	interleukin 22 receptor, alpha 2	52030	0.14
chr7_27217830_27218176	0.77	RP1-170O19.20	Uncharacterized protein	1629	0.13
chr4_26577939_26578090	0.77	TBC1D19	TBC1 domain family, member 19	45	0.98
chr2_134432019_134432170	0.76	ENSG00000200708	.	78432	0.11
chr2_56412283_56412467	0.75	AC007743.1		327	0.83
chr8_119344627_119344778	0.75	AC023590.1	Uncharacterized protein	50221	0.19
chr5_92919468_92919846	0.75	NR2F1	nuclear receptor subfamily 2, group F, member 1	614	0.69
chr7_134474351_134474502	0.75	CALD1	caldesmon 1	9997	0.29
chr17_79609293_79609648	0.75	TSPAN10	tetraspanin 10	121	0.91
chr13_102151652_102151813	0.75	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	9429	0.3
chr3_110132950_110133243	0.75	ENSG00000221206	.	137716	0.05
chr18_57385985_57386276	0.75	CCBE1	collagen and calcium binding EGF domains 1	21518	0.16
chr1_210405641_210405792	0.75	SERTAD4	SERTA domain containing 4	428	0.6
chr12_76271592_76272084	0.75	ENSG00000243420	.	80072	0.1
chr9_86875979_86876265	0.74	RP11-380F14.2		17012	0.26
chr3_100784704_100784898	0.74	ABI3BP	ABI family, member 3 (NESH) binding protein	72442	0.11
chr11_8889856_8890095	0.74	ST5	suppression of tumorigenicity 5	2489	0.19
chr17_13965501_13965785	0.74	ENSG00000236088	.	7132	0.24
chr1_94159203_94159501	0.73	BCAR3	breast cancer anti-estrogen resistance 3	11967	0.24
chr6_150173382_150173533	0.73	RP11-350J20.12		141	0.93
chr17_13266074_13266343	0.73	ENSG00000266115	.	137437	0.05
chr6_148664824_148664993	0.73	SASH1	SAM and SH3 domain containing 1	1179	0.59
chr2_175854784_175854957	0.73	ENSG00000201425	.	12339	0.15
chr10_33626258_33626516	0.73	NRP1	neuropilin 1	1197	0.6
chr6_133890397_133891036	0.73	RP3-323P13.2		57850	0.15
chr1_240760211_240760638	0.73	RP11-467I20.6		6376	0.21
chr4_52903753_52904199	0.73	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)	449	0.84
chr17_46651973_46652199	0.73	HOXB3	homeobox B3	237	0.8
chr15_74222319_74222668	0.72	LOXL1-AS1	LOXL1 antisense RNA 1	1904	0.26
chr12_26112779_26113361	0.72	RASSF8-AS1	RASSF8 atnisense RNA 1	372	0.8
chr3_147648289_147648638	0.72	ENSG00000221431	.	19175	0.29
chr1_240258821_240259228	0.72	FMN2	formin 2	3844	0.31
chr5_40915264_40915466	0.72	ENSG00000253098	.	4135	0.21
chr6_31082599_31082878	0.72	PSORS1C1	psoriasis susceptibility 1 candidate 1	130	0.91
chr10_48336328_48336544	0.72	ZNF488	zinc finger protein 488	18588	0.14
chr7_41926126_41926481	0.71	AC005027.3		181370	0.03
chr1_245255499_245255650	0.71	EFCAB2	EF-hand calcium binding domain 2	8816	0.18
chr1_97610415_97610576	0.71	DPYD-AS1	DPYD antisense RNA 1	49016	0.19
chr1_78005180_78005370	0.71	AK5	adenylate kinase 5	7483	0.25
chr19_49561050_49561269	0.71	CGB7	chorionic gonadotropin, beta polypeptide 7	151	0.85
chr12_85305306_85305778	0.71	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	261	0.96
chr4_151062450_151062706	0.71	DCLK2	doublecortin-like kinase 2	62398	0.13
chr4_123751095_123751246	0.71	ENSG00000253069	.	3001	0.24
chr1_8433877_8434267	0.71	RERE	arginine-glutamic acid dipeptide (RE) repeats	9174	0.19
chr14_29705884_29706116	0.71	ENSG00000257522	.	141862	0.05
chrX_100740463_100741131	0.71	ARMCX4	armadillo repeat containing, X-linked 4	2234	0.26
chr2_191511664_191511958	0.71	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)	339	0.9
chr5_56834430_56834632	0.70	ACTBL2	actin, beta-like 2	55895	0.13
chr10_95240803_95240954	0.70	MYOF	myoferlin	1073	0.51
chr13_113832243_113832413	0.70	RP11-98F14.11		12831	0.12
chr6_117852473_117852851	0.70	DCBLD1	discoidin, CUB and LCCL domain containing 1	48837	0.12
chr2_24398374_24398902	0.70	FAM228A	family with sequence similarity 228, member A	284	0.75
chr5_91977319_91977616	0.70	ENSG00000221810	.	75753	0.13
chr19_16179581_16179939	0.69	TPM4	tropomyosin 4	1250	0.44
chr5_34658039_34658190	0.69	CTD-2024P10.1		759	0.56
chr4_55945978_55946129	0.69	ENSG00000244034	.	16151	0.17
chr3_13421009_13421370	0.69	NUP210	nucleoporin 210kDa	40620	0.18
chr3_134125279_134125630	0.69	ENSG00000221313	.	3528	0.24
chr6_150218005_150218162	0.69	RAET1E	retinoic acid early transcript 1E	888	0.45
chr4_81195528_81195918	0.69	FGF5	fibroblast growth factor 5	7930	0.26
chr10_17275800_17275972	0.69	RP11-124N14.3		946	0.49

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.9	GO:0070141	response to UV-A(GO:0070141)
0.4	1.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.4	1.2	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.4	1.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.4	1.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.4	1.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.3	0.3	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.3	1.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.3	1.0	GO:0060242	contact inhibition(GO:0060242)
0.3	0.9	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.3	1.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.3	0.8	GO:0010996	response to auditory stimulus(GO:0010996)
0.3	1.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.3	1.0	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2	0.7	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2	0.9	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	0.6	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.6	GO:2000188	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.2	1.2	GO:0016264	gap junction assembly(GO:0016264)
0.2	0.4	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.2	0.8	GO:0008218	bioluminescence(GO:0008218)
0.2	0.8	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.6	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.2	0.4	GO:0010159	specification of organ position(GO:0010159)
0.2	0.5	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.2	0.9	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2	0.5	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	0.5	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.7	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	0.4	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.1	0.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.4	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	1.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.4	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.5	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	0.3	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.8	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.6	GO:0070474	uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1	1.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.9	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.7	GO:0055091	phospholipid homeostasis(GO:0055091)
0.1	0.4	GO:0008215	spermine metabolic process(GO:0008215)
0.1	3.1	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.4	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.3	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.4	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.7	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	1.2	GO:0001660	fever generation(GO:0001660)
0.1	0.3	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.1	0.5	GO:0002068	glandular epithelial cell development(GO:0002068)
0.1	0.3	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.4	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.1	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1	0.3	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.3	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.7	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.1	0.5	GO:0006561	proline biosynthetic process(GO:0006561)
0.1	0.3	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	0.2	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656) negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.6	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	0.3	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.1	0.4	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.6	GO:0048745	smooth muscle tissue development(GO:0048745)
0.1	0.3	GO:0051182	coenzyme transport(GO:0051182)
0.1	1.3	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.1	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.2	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.6	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.2	GO:0007350	blastoderm segmentation(GO:0007350)
0.1	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.4	GO:0060134	prepulse inhibition(GO:0060134)
0.1	0.2	GO:0060536	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1	0.7	GO:0032456	endocytic recycling(GO:0032456)
0.1	1.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.1	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0060013	righting reflex(GO:0060013)
0.1	0.4	GO:0001945	lymph vessel development(GO:0001945)
0.1	1.0	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.7	GO:0043030	regulation of macrophage activation(GO:0043030)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.1	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.3	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.5	GO:0031000	response to caffeine(GO:0031000)
0.1	0.3	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.3	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.1	0.2	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.3	GO:0018126	protein hydroxylation(GO:0018126)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.6	GO:0045773	positive regulation of axon extension(GO:0045773)
0.1	0.3	GO:0032288	myelin assembly(GO:0032288)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.2	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1	0.1	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.1	GO:0060039	pericardium development(GO:0060039)
0.1	0.7	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.9	GO:0008038	neuron recognition(GO:0008038)
0.1	0.2	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	0.5	GO:0007567	parturition(GO:0007567)
0.1	0.2	GO:0009648	photoperiodism(GO:0009648)
0.1	0.2	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.1	0.1	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.1	1.1	GO:0016486	peptide hormone processing(GO:0016486)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.1	GO:0021591	ventricular system development(GO:0021591)
0.1	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.1	0.4	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.4	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.2	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.2	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.1	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	1.1	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	1.0	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.3	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.0	GO:0060435	bronchiole development(GO:0060435)
0.0	0.5	GO:0031103	axon regeneration(GO:0031103)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.5	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	2.1	GO:0001764	neuron migration(GO:0001764)
0.0	0.9	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.4	GO:0043113	receptor clustering(GO:0043113)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.6	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.7	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942) positive regulation of neuroepithelial cell differentiation(GO:1902913)
0.0	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.2	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.2	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.1	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.4	GO:0006553	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.8	GO:0007340	acrosome reaction(GO:0007340)
0.0	5.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.7	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0060296	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.4	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.1	GO:0060179	male courtship behavior(GO:0008049) male mating behavior(GO:0060179)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.0	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0007492	endoderm development(GO:0007492)
0.0	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.2	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.8	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.0	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.6	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.4	GO:0002544	chronic inflammatory response(GO:0002544)
0.0	0.0	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0048048	embryonic eye morphogenesis(GO:0048048)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.3	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.3	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0	0.1	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.1	GO:0010092	specification of organ identity(GO:0010092)
0.0	0.3	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.3	GO:0014075	response to amine(GO:0014075)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:2000171	negative regulation of dendrite morphogenesis(GO:0050774) negative regulation of dendrite development(GO:2000171)
0.0	1.0	GO:0007569	cell aging(GO:0007569)
0.0	0.2	GO:0009437	amino-acid betaine metabolic process(GO:0006577) carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.6	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.2	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0048319	axial mesoderm development(GO:0048318) axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.2	GO:0016553	base conversion or substitution editing(GO:0016553)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0043502	regulation of muscle adaptation(GO:0043502)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0060976	coronary vasculature development(GO:0060976)
0.0	0.4	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.4	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.2	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.1	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.2	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.2	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0	0.2	GO:0090280	positive regulation of calcium ion import(GO:0090280)
0.0	0.3	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0044268	regulation of angiotensin levels in blood(GO:0002002) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268) regulation of angiotensin metabolic process(GO:0060177)
0.0	0.0	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.0	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
0.0	0.0	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0031102	neuron projection regeneration(GO:0031102)
0.0	0.1	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.6	GO:0007368	determination of left/right symmetry(GO:0007368)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.2	GO:0060828	regulation of canonical Wnt signaling pathway(GO:0060828)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.1	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.4	GO:0007030	Golgi organization(GO:0007030)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:1902749	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.0	0.4	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0051503	purine nucleotide transport(GO:0015865) adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.1	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.9	GO:0009408	response to heat(GO:0009408)
0.0	0.0	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.0	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.1	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.1	GO:0043277	apoptotic cell clearance(GO:0043277)
0.0	0.2	GO:0051058	negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0	0.4	GO:0006493	protein O-linked glycosylation(GO:0006493)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0060065	uterus development(GO:0060065)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.2	GO:0072164	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0	0.0	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.3	GO:0031572	G2 DNA damage checkpoint(GO:0031572)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.2	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.1	GO:0033194	response to hydroperoxide(GO:0033194)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.4	GO:0010001	glial cell differentiation(GO:0010001)
0.0	0.1	GO:0048706	embryonic skeletal system development(GO:0048706)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0043650	dicarboxylic acid biosynthetic process(GO:0043650)
0.0	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.3	GO:0007205	protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.1	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	1.5	GO:0007517	muscle organ development(GO:0007517)
0.0	0.1	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0007422	peripheral nervous system development(GO:0007422)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0007379	segment specification(GO:0007379)
0.0	0.2	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:0048806	genitalia development(GO:0048806)
0.0	0.0	GO:0072112	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0003309	type B pancreatic cell differentiation(GO:0003309)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0000491	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.3	GO:0042472	inner ear morphogenesis(GO:0042472)
0.0	0.1	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0019915	lipid storage(GO:0019915)
0.0	0.0	GO:0048087	positive regulation of developmental pigmentation(GO:0048087)
0.0	0.0	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.0	GO:0050974	detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0	1.8	GO:0006813	potassium ion transport(GO:0006813)
0.0	0.1	GO:0016575	histone deacetylation(GO:0016575)
0.0	0.1	GO:0050773	regulation of dendrite development(GO:0050773)
0.0	0.0	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0014015	positive regulation of gliogenesis(GO:0014015)
0.0	0.0	GO:0002858	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0042246	tissue regeneration(GO:0042246)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0034505	tooth mineralization(GO:0034505)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0007343	egg activation(GO:0007343)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0006991	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.0	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.1	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.0	GO:0060767	epithelial cell proliferation involved in prostate gland development(GO:0060767)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.7	GO:0005614	interstitial matrix(GO:0005614)
0.3	1.8	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	1.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	1.0	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.7	GO:0043260	laminin-11 complex(GO:0043260)
0.2	0.8	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	0.5	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.2	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.2	0.5	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.7	GO:0071437	invadopodium(GO:0071437)
0.1	0.7	GO:0001739	sex chromatin(GO:0001739)
0.1	0.9	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.5	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.4	GO:0070852	cell body fiber(GO:0070852)
0.1	1.0	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	1.2	GO:0043205	fibril(GO:0043205)
0.1	0.7	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.8	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.6	GO:0005581	collagen trimer(GO:0005581)
0.1	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.4	GO:0005915	zonula adherens(GO:0005915)
0.1	0.6	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.1	GO:0016342	catenin complex(GO:0016342)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.4	GO:0002102	podosome(GO:0002102)
0.1	0.7	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.2	GO:0043083	synaptic cleft(GO:0043083)
0.1	1.0	GO:0005811	lipid particle(GO:0005811)
0.1	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.8	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	4.6	GO:0005925	focal adhesion(GO:0005925)
0.0	1.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.0	GO:0005922	connexon complex(GO:0005922)
0.0	2.8	GO:0030426	growth cone(GO:0030426)
0.0	0.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.4	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0	0.3	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	2.4	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.9	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	4.9	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.9	GO:0043679	axon terminus(GO:0043679)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	7.3	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.6	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	3.2	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0001939	female pronucleus(GO:0001939)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.5	GO:0030118	clathrin coat(GO:0030118)
0.0	0.3	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	1.3	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.0	GO:0032806	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) carboxy-terminal domain protein kinase complex(GO:0032806)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	3.3	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.5	1.4	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3	1.0	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.3	1.0	GO:0070052	collagen V binding(GO:0070052)
0.3	1.0	GO:0004995	tachykinin receptor activity(GO:0004995)
0.3	1.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	0.9	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.3	1.3	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2	0.7	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	1.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.2	0.8	GO:0048495	Roundabout binding(GO:0048495)
0.2	0.2	GO:0043559	insulin binding(GO:0043559)
0.2	1.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.2	0.5	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	1.0	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	0.5	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2	0.6	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.4	GO:0005113	patched binding(GO:0005113)
0.1	1.2	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	1.9	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.4	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1	0.8	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.4	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.4	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.4	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.8	GO:0030507	spectrin binding(GO:0030507)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	1.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.3	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.3	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	3.8	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.5	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	1.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.2	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.8	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	1.5	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.7	GO:0017166	vinculin binding(GO:0017166)
0.1	0.5	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	0.3	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.2	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.4	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	0.8	GO:0030553	cGMP binding(GO:0030553)
0.1	0.7	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.5	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.2	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.2	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.2	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.4	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.9	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.8	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.9	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.3	GO:0001848	complement binding(GO:0001848)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.2	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.0	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.1	GO:0052659	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.2	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	1.6	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	1.1	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.5	GO:0016918	retinal binding(GO:0016918)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.4	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	1.0	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.4	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.4	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.4	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.2	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	8.2	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0016416	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.3	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.5	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.3	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.3	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.4	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.3	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	1.8	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	2.0	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0016595	glutamate binding(GO:0016595)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.0	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	1.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.4	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.6	GO:0005178	integrin binding(GO:0005178)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.3	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.3	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	1.2	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0055102	lipase inhibitor activity(GO:0055102)
0.0	0.4	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	5.9	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.0	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.4	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.0	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.0	GO:0030546	receptor activator activity(GO:0030546)
0.0	0.0	GO:0016413	O-acetyltransferase activity(GO:0016413)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	2.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.6	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	3.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	5.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.6	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	1.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.4	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	1.4	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.9	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.2	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.5	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.0	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.5	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	5.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.9	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	1.0	PID BMP PATHWAY	BMP receptor signaling
0.0	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	1.4	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID FGF PATHWAY	FGF signaling pathway
0.0	3.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.3	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.3	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.3	PID TGFBR PATHWAY	TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	0.2	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.2	3.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2	3.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	1.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	2.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.1	1.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	1.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	3.3	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.7	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1	1.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	2.7	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.1	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1	0.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	0.6	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.1	1.0	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	0.8	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	0.8	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.9	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.5	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.5	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.0	0.8	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.5	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.3	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.8	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.0	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.2	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport

Results for GFI1B

Z-value: 3.91

Motif logo

Transcription factors associated with GFI1B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the GFI1B motif across conditions

Conditions sorted by the z-value of the GFI1B motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: