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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GLIS3

Z-value: 0.74

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Transcription factors associated with GLIS3

Gene Symbol	Gene ID	Gene Info
GLIS3 Ensembl NCBI GeneCards UniProt	ENSG00000107249.17	GLIS3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GLIS3	chr9_4293611_4293830	4776	0.234420	0.92	4.2e-04	Click!
GLIS3	chr9_4301764_4301915	1923	0.325141	0.91	5.8e-04	Click!
GLIS3	chr9_4144974_4145179	117	0.979043	0.89	1.5e-03	Click!
GLIS3	chr9_4278077_4278228	20344	0.199196	0.89	1.5e-03	Click!
GLIS3	chr9_4225853_4226004	72568	0.104218	0.86	2.9e-03	Click!

Activity of the GLIS3 motif across conditions

Conditions sorted by the z-value of the GLIS3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chrX_107178963_107179207	0.68	RP6-191P20.4		125	0.97
chr17_59476045_59476898	0.61	RP11-332H18.4		260	0.74
chr2_27717409_27717598	0.59	FNDC4	fibronectin type III domain containing 4	609	0.54
chr2_190042287_190042516	0.54	COL5A2	collagen, type V, alpha 2	2204	0.37
chr22_51136330_51136565	0.52	ENSG00000206841	.	6656	0.12
chr16_86601461_86601775	0.50	RP11-463O9.5		251	0.8
chr2_121493751_121494304	0.49	GLI2	GLI family zinc finger 2	204	0.97
chr3_48632919_48633070	0.42	COL7A1	collagen, type VII, alpha 1	294	0.8
chr3_50193036_50193699	0.42	RP11-493K19.3		86	0.87
chr7_71098294_71098514	0.41	ENSG00000199940	.	52328	0.19
chr5_140887996_140888228	0.40	DIAPH1	diaphanous-related formin 1	17602	0.08
chr1_17867304_17867455	0.39	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like	1049	0.62
chr21_38071587_38071762	0.38	SIM2	single-minded family bHLH transcription factor 2	240	0.92
chr2_236401822_236402641	0.37	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	502	0.83
chr17_79397329_79397532	0.37	RP11-1055B8.7	BAH and coiled-coil domain-containing protein 1	7966	0.11
chr14_29228686_29229081	0.36	RP11-966I7.1		5586	0.17
chr20_6103412_6103655	0.36	FERMT1	fermitin family member 1	144	0.97
chr8_494526_494820	0.34	TDRP	testis development related protein	164	0.97
chr3_157260663_157261197	0.34	C3orf55	chromosome 3 open reading frame 55	105	0.98
chr12_122467875_122468026	0.34	BCL7A	B-cell CLL/lymphoma 7A	8158	0.22
chr13_110958781_110959436	0.34	COL4A1	collagen, type IV, alpha 1	370	0.6
chr11_119597594_119597745	0.33	PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	1594	0.37
chr17_70120328_70120596	0.33	SOX9	SRY (sex determining region Y)-box 9	3301	0.38
chr16_51184162_51184313	0.32	SALL1	spalt-like transcription factor 1	271	0.87
chr22_44315340_44315603	0.32	PNPLA3	patatin-like phospholipase domain containing 3	4148	0.18
chr22_43523181_43523332	0.31	MCAT	malonyl CoA:ACP acyltransferase (mitochondrial)	15714	0.13
chr12_46886554_46886705	0.31	SLC38A2	solute carrier family 38, member 2	119979	0.06
chr16_67215217_67215453	0.31	KIAA0895L	KIAA0895-like	1370	0.18
chr19_16936008_16936179	0.31	SIN3B	SIN3 transcription regulator family member B	4118	0.16
chr11_61739742_61739933	0.30	AP003733.1	Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801	4384	0.15
chr8_11421540_11421831	0.30	RP11-148O21.2		4156	0.18
chr1_186649638_186650434	0.30	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	477	0.89
chr9_12775321_12775833	0.29	LURAP1L	leucine rich adaptor protein 1-like	557	0.78
chr15_84116498_84116804	0.29	SH3GL3	SH3-domain GRB2-like 3	368	0.92
chr16_69998972_69999655	0.29	CLEC18A	C-type lectin domain family 18, member A	13669	0.14
chr22_30796002_30796153	0.29	SEC14L2	SEC14-like 2 (S. cerevisiae)	1511	0.18
chr2_177001412_177001990	0.29	HOXD3	homeobox D3	16	0.5
chr17_2310404_2311021	0.28	MNT	MAX network transcriptional repressor	6300	0.12
chr10_62760865_62761099	0.28	RHOBTB1	Rho-related BTB domain containing 1	216	0.97
chr1_31887122_31887273	0.28	SERINC2	serine incorporator 2	537	0.74
chr13_107185066_107185426	0.28	EFNB2	ephrin-B2	2216	0.4
chr2_165477169_165477439	0.27	GRB14	growth factor receptor-bound protein 14	684	0.79
chr19_56166514_56167932	0.27	U2AF2	U2 small nuclear RNA auxiliary factor 2	792	0.34
chr3_184300809_184300975	0.27	EPHB3	EPH receptor B3	21320	0.18
chr17_75474006_75474173	0.27	SEPT9	septin 9	2764	0.22
chr1_183236957_183237240	0.27	NMNAT2	nicotinamide nucleotide adenylyltransferase 2	36911	0.19
chr11_61486524_61486808	0.26	MYRF	myelin regulatory factor	33455	0.11
chr7_27225817_27225968	0.26	HOXA11-AS	HOXA11 antisense RNA	739	0.31
chr4_151503456_151503607	0.26	MAB21L2	mab-21-like 2 (C. elegans)	454	0.84
chr10_88728248_88728709	0.26	ADIRF	adipogenesis regulatory factor	289	0.5
chr20_23031599_23032105	0.25	THBD	thrombomodulin	1474	0.34
chr9_140506939_140507169	0.25	C9orf37	chromosome 9 open reading frame 37	6211	0.12
chr8_128864051_128864244	0.25	ENSG00000249859	.	55939	0.13
chr14_69015576_69015827	0.25	CTD-2325P2.4		79461	0.1
chr2_75787048_75787447	0.25	EVA1A	eva-1 homolog A (C. elegans)	792	0.61
chr8_99014292_99014443	0.25	MATN2	matrilin 2	14405	0.15
chr17_79438730_79438973	0.25	RP11-1055B8.8		9888	0.1
chr10_103330110_103330718	0.24	DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	8	0.98
chr5_112582093_112582348	0.24	MCC	mutated in colorectal cancers	11846	0.27
chr19_5578062_5578357	0.24	SAFB2	scaffold attachment factor B2	44782	0.11
chr2_127643626_127643777	0.24	AC114783.1	Protein LOC339760	12771	0.28
chr3_71158955_71159120	0.24	FOXP1	forkhead box P1	20707	0.28
chr9_81871858_81872685	0.24	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	314417	0.01
chr1_32263785_32263971	0.24	SPOCD1	SPOC domain containing 1	439	0.79
chr11_58730865_58731226	0.24	RP11-142C4.6		15713	0.15
chr16_65155038_65155536	0.23	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	546	0.88
chr3_114169976_114170457	0.23	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr6_85484117_85484534	0.23	TBX18	T-box 18	10088	0.3
chr15_96100470_96100831	0.23	ENSG00000222076	.	188383	0.03
chrX_34675593_34676078	0.23	TMEM47	transmembrane protein 47	430	0.92
chr17_45197869_45198099	0.23	ENSG00000221016	.	2116	0.25
chr22_46933754_46934840	0.22	CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1	1230	0.46
chr15_75944753_75944922	0.22	SNX33	sorting nexin 33	2740	0.14
chr12_124004050_124004201	0.22	RILPL1	Rab interacting lysosomal protein-like 1	5150	0.17
chr2_202723535_202724043	0.22	ENSG00000221374	.	17937	0.16
chr12_120032319_120032470	0.22	TMEM233	transmembrane protein 233	1130	0.49
chr2_133173748_133173945	0.22	GPR39	G protein-coupled receptor 39	301	0.92
chr8_42063953_42065062	0.22	PLAT	plasminogen activator, tissue	576	0.71
chr9_134287538_134287689	0.21	PRRC2B	proline-rich coiled-coil 2B	17864	0.19
chr11_89597318_89597927	0.21	TRIM64B	tripartite motif containing 64B	11563	0.22
chr7_131240036_131240570	0.21	PODXL	podocalyxin-like	1063	0.65
chr4_164265165_164265569	0.21	NPY5R	neuropeptide Y receptor Y5	113	0.9
chr7_28997325_28997548	0.21	CTB-113D17.1		22147	0.2
chr2_151343410_151343893	0.21	RND3	Rho family GTPase 3	530	0.88
chr9_116356336_116356765	0.21	RGS3	regulator of G-protein signaling 3	784	0.67
chr20_43970794_43971114	0.21	SDC4	syndecan 4	6110	0.13
chr8_120879463_120879614	0.21	ENSG00000244642	.	4636	0.17
chr14_58332211_58332467	0.21	SLC35F4	solute carrier family 35, member F4	441	0.87
chr3_157155512_157155783	0.21	PTX3	pentraxin 3, long	1069	0.63
chr3_66007529_66007703	0.20	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	16367	0.19
chr21_47394558_47394771	0.20	COL6A1	collagen, type VI, alpha 1	6987	0.21
chr11_1896066_1896383	0.20	LSP1	lymphocyte-specific protein 1	1483	0.24
chr16_2085550_2085759	0.20	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	2382	0.09
chr7_64035084_64035528	0.20	ZNF680	zinc finger protein 680	11822	0.28
chr1_2569102_2569253	0.20	MMEL1	membrane metallo-endopeptidase-like 1	4696	0.16
chr15_68573802_68573977	0.20	FEM1B	fem-1 homolog b (C. elegans)	1592	0.39
chr17_77997988_77998139	0.20	CTD-2529O21.2		333	0.85
chr2_16832297_16832583	0.20	FAM49A	family with sequence similarity 49, member A	14656	0.3
chr17_6922316_6922467	0.20	RP11-589P10.7		342	0.53
chr18_57386327_57386692	0.20	CCBE1	collagen and calcium binding EGF domains 1	21897	0.15
chr3_149094469_149095370	0.20	TM4SF1-AS1	TM4SF1 antisense RNA 1	646	0.47
chr8_22443451_22443742	0.19	AC037459.4	Uncharacterized protein	3191	0.12
chr12_26266071_26266589	0.19	SSPN	sarcospan	8594	0.18
chr19_51455841_51455992	0.19	KLK5	kallikrein-related peptidase 5	282	0.77
chr1_204042818_204043418	0.19	SOX13	SRY (sex determining region Y)-box 13	36	0.98
chr6_4733420_4733615	0.19	CDYL	chromodomain protein, Y-like	27124	0.2
chr20_48599552_48599945	0.19	SNAI1	snail family zinc finger 1	212	0.92
chr12_96183320_96183471	0.19	NTN4	netrin 4	331	0.86
chr2_36678228_36678401	0.19	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	62519	0.12
chr19_41195400_41196566	0.19	NUMBL	numb homolog (Drosophila)-like	44	0.96
chr4_57203544_57203695	0.19	ENSG00000251823	.	6236	0.18
chr19_7953457_7953661	0.19	LRRC8E	leucine rich repeat containing 8 family, member E	123	0.88
chr19_13983804_13984015	0.19	ENSG00000207613	.	1604	0.17
chr13_110979643_110979794	0.19	COL4A2	collagen, type IV, alpha 2	20104	0.2
chr3_44040787_44041403	0.18	ENSG00000252980	.	71484	0.12
chr10_70359131_70359282	0.18	TET1	tet methylcytosine dioxygenase 1	38793	0.13
chr17_75523143_75523294	0.18	SEPT9	septin 9	45223	0.13
chr7_130131272_130131861	0.18	MEST	mesoderm specific transcript	368	0.77
chr15_68580618_68580911	0.18	FEM1B	fem-1 homolog b (C. elegans)	829	0.64
chr1_6556688_6556983	0.18	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	79	0.95
chr11_833873_834149	0.18	CD151	CD151 molecule (Raph blood group)	861	0.26
chr9_110513848_110514093	0.18	AL162389.1	Uncharacterized protein	26449	0.19
chr17_75404849_75405000	0.18	SEPT9	septin 9	3765	0.19
chr20_3657828_3657979	0.18	ADAM33	ADAM metallopeptidase domain 33	4847	0.17
chr9_137445335_137445486	0.18	COL5A1	collagen, type V, alpha 1	88210	0.08
chr20_43729394_43729952	0.18	KCNS1	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1	77	0.96
chr17_77752893_77753171	0.18	CBX2	chromobox homolog 2	1039	0.43
chr12_47471040_47471191	0.17	PCED1B	PC-esterase domain containing 1B	2271	0.31
chr1_150480831_150481087	0.17	ECM1	extracellular matrix protein 1	376	0.77
chr6_28641788_28642196	0.17	ENSG00000272278	.	25950	0.18
chr11_61159610_61160825	0.17	TMEM216	transmembrane protein 216	352	0.79
chr16_70221940_70222878	0.17	CLEC18C	C-type lectin domain family 18, member C	14349	0.1
chr9_137221469_137221673	0.17	RXRA	retinoid X receptor, alpha	3145	0.33
chr5_140753330_140753954	0.17	PCDHGA6	protocadherin gamma subfamily A, 6	9	0.91
chr12_6930752_6931082	0.17	GPR162	G protein-coupled receptor 162	47	0.93
chr15_74344226_74344377	0.17	ENSG00000244612	.	20738	0.13
chr17_77925559_77925739	0.17	TBC1D16	TBC1 domain family, member 16	163	0.96
chr20_25565265_25566139	0.17	NINL	ninein-like	451	0.81
chr12_132316928_132317093	0.17	MMP17	matrix metallopeptidase 17 (membrane-inserted)	3925	0.2
chr17_74542570_74542721	0.17	RP11-666A8.7		3388	0.1
chr16_51188825_51189552	0.17	SALL1	spalt-like transcription factor 1	4002	0.28
chr11_43955270_43955437	0.17	C11orf96	chromosome 11 open reading frame 96	8461	0.16
chr1_39569795_39569946	0.16	MACF1	microtubule-actin crosslinking factor 1	1213	0.46
chr17_41909774_41910015	0.16	MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)	284	0.86
chr17_36902558_36902709	0.16	PCGF2	polycomb group ring finger 2	248	0.78
chr1_67142291_67142442	0.16	AL139147.1	Uncharacterized protein	344	0.88
chr22_32022509_32022660	0.16	PISD	phosphatidylserine decarboxylase	304	0.91
chr20_10634629_10634907	0.16	JAG1	jagged 1	8386	0.25
chr1_45082713_45082906	0.16	RNF220	ring finger protein 220	9189	0.17
chr7_73245792_73245943	0.16	CLDN4	claudin 4	674	0.63
chr15_40616235_40616987	0.16	LINC00984	long intergenic non-protein coding RNA 984	806	0.39
chr16_4348992_4349159	0.16	GLIS2	GLIS family zinc finger 2	15687	0.13
chr22_21311135_21311286	0.16	ENSG00000266366	.	1761	0.2
chr9_695532_695683	0.16	RP11-130C19.3		10052	0.22
chr14_100041328_100041479	0.16	CCDC85C	coiled-coil domain containing 85C	1526	0.37
chr16_74440490_74441404	0.16	CLEC18B	C-type lectin domain family 18, member B	14343	0.14
chr5_73770430_73770700	0.16	ENSG00000244326	.	156754	0.04
chr7_5458775_5459294	0.15	AC093620.5		424	0.46
chr16_31548902_31549248	0.15	AHSP	alpha hemoglobin stabilizing protein	9777	0.11
chr3_48777290_48777441	0.15	PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	12386	0.13
chr3_175244326_175245006	0.15	ENSG00000201648	.	82601	0.1
chr11_393450_393735	0.15	PKP3	plakophilin 3	129	0.92
chr4_125825441_125825711	0.15	ANKRD50	ankyrin repeat domain 50	191689	0.03
chr17_68165729_68165994	0.15	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2	185	0.66
chr2_58655964_58656121	0.15	FANCL	Fanconi anemia, complementation group L	187535	0.03
chr5_140762477_140762699	0.15	PCDHGA7	protocadherin gamma subfamily A, 7	121	0.87
chr8_27491561_27492240	0.15	SCARA3	scavenger receptor class A, member 3	202	0.93
chr1_40421563_40422081	0.15	MFSD2A	major facilitator superfamily domain containing 2A	1000	0.48
chr22_19946584_19946980	0.15	COMT	catechol-O-methyltransferase	3288	0.15
chr6_21886388_21886539	0.15	ENSG00000222515	.	199310	0.03
chr11_63803897_63804159	0.15	RP11-21A7A.2		586	0.65
chr2_151335102_151335779	0.15	RND3	Rho family GTPase 3	6456	0.35
chr6_80656707_80657785	0.15	ELOVL4	ELOVL fatty acid elongase 4	51	0.98
chr3_133967997_133968801	0.15	RYK	receptor-like tyrosine kinase	1038	0.66
chr1_150480597_150480804	0.15	ECM1	extracellular matrix protein 1	117	0.94
chrX_22153526_22153707	0.15	PHEX-AS1	PHEX antisense RNA 1	37484	0.16
chr3_138957437_138957611	0.14	MRPS22	mitochondrial ribosomal protein S22	105337	0.06
chr8_131503545_131503696	0.14	ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	47714	0.2
chr13_110959773_110960124	0.14	COL4A2	collagen, type IV, alpha 2	334	0.6
chr5_14036568_14037099	0.14	DNAH5	dynein, axonemal, heavy chain 5	92181	0.09
chr6_56716060_56716427	0.14	DST	dystonin	506	0.82
chr14_23237291_23237442	0.14	OXA1L	oxidase (cytochrome c) assembly 1-like	1438	0.23
chr1_156718751_156718902	0.14	HDGF	hepatoma-derived growth factor	2259	0.16
chr20_4129930_4130735	0.14	SMOX	spermine oxidase	750	0.71
chr1_223921059_223921210	0.14	CAPN2	calpain 2, (m/II) large subunit	21100	0.19
chr14_55121110_55121261	0.14	SAMD4A	sterile alpha motif domain containing 4A	86548	0.09
chr16_4424352_4424847	0.14	VASN	vasorin	2750	0.17
chr8_54789629_54790008	0.14	RP11-1070A24.2		609	0.71
chr13_36705915_36706066	0.14	DCLK1	doublecortin-like kinase 1	547	0.84
chr3_122786767_122787219	0.14	PDIA5	protein disulfide isomerase family A, member 5	798	0.71
chr1_209603784_209603935	0.14	ENSG00000230937	.	1619	0.52
chr19_47163250_47163584	0.14	DACT3-AS1	DACT3 antisense RNA 1	204	0.83
chrX_153601896_153602918	0.14	FLNA	filamin A, alpha	587	0.54
chr13_72440002_72440456	0.14	DACH1	dachshund homolog 1 (Drosophila)	678	0.82
chr13_110972530_110972681	0.14	COL4A2	collagen, type IV, alpha 2	12991	0.21
chr12_109901272_109901510	0.14	KCTD10	potassium channel tetramerization domain containing 10	3191	0.21
chr14_78447028_78447687	0.14	ENSG00000199440	.	159872	0.03
chr11_45922009_45922186	0.14	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	3996	0.14
chr2_236578616_236578898	0.14	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	509	0.87
chr17_77767116_77767731	0.14	CBX8	chromobox homolog 8	3492	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.4	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.4	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.3	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.2	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.3	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.2	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.2	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.2	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.2	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.1	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0046958	nonassociative learning(GO:0046958)
0.0	0.2	GO:0045745	positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.1	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.2	GO:0009650	UV protection(GO:0009650)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.1	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.0	GO:0060453	regulation of gastric acid secretion(GO:0060453)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.2	GO:1900077	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0	0.0	GO:0070141	response to UV-A(GO:0070141)
0.0	0.2	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0006853	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0070306	lens fiber cell differentiation(GO:0070306)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.5	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.3	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.0	GO:0043159	acrosomal matrix(GO:0043159)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.3	GO:0043236	laminin binding(GO:0043236)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.3	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.0	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.0	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0042806	fucose binding(GO:0042806)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.3	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.3	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL	Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.9	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions