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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for GLIS3

Z-value: 0.74

Motif logo

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Transcription factors associated with GLIS3

Gene Symbol Gene ID Gene Info
GLIS3
ENSG00000107249.17 GLIS family zinc finger 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_4293611_4293830GLIS347760.2344200.924.2e-04Click!
chr9_4301764_4301915GLIS319230.3251410.915.8e-04Click!
chr9_4144974_4145179GLIS31170.9790430.891.5e-03Click!
chr9_4278077_4278228GLIS3203440.1991960.891.5e-03Click!
chr9_4225853_4226004GLIS3725680.1042180.862.9e-03Click!

Activity of the GLIS3 motif across conditions

Conditions sorted by the z-value of the GLIS3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chrX_107178963_107179207 0.68 RP6-191P20.4
125
 0.97
chr17_59476045_59476898 0.61 RP11-332H18.4
260
 0.74
chr2_27717409_27717598 0.59 FNDC4
 fibronectin type III domain containing 4
 609
 0.54
chr2_190042287_190042516 0.54 COL5A2
 collagen, type V, alpha 2
 2204
 0.37
chr22_51136330_51136565 0.52 ENSG00000206841
 .
 6656
 0.12
chr16_86601461_86601775 0.50 RP11-463O9.5
251
 0.8
chr2_121493751_121494304 0.49 GLI2
 GLI family zinc finger 2
 204
 0.97
chr3_48632919_48633070 0.42 COL7A1
 collagen, type VII, alpha 1
 294
 0.8
chr3_50193036_50193699 0.42 RP11-493K19.3
86
 0.87
chr7_71098294_71098514 0.41 ENSG00000199940
 .
 52328
 0.19
chr5_140887996_140888228 0.40 DIAPH1
 diaphanous-related formin 1
 17602
 0.08
chr1_17867304_17867455 0.39 ARHGEF10L
 Rho guanine nucleotide exchange factor (GEF) 10-like
 1049
 0.62
chr21_38071587_38071762 0.38 SIM2
 single-minded family bHLH transcription factor 2
 240
 0.92
chr2_236401822_236402641 0.37 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 502
 0.83
chr17_79397329_79397532 0.37 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 7966
 0.11
chr14_29228686_29229081 0.36 RP11-966I7.1
5586
 0.17
chr20_6103412_6103655 0.36 FERMT1
 fermitin family member 1
 144
 0.97
chr8_494526_494820 0.34 TDRP
 testis development related protein
 164
 0.97
chr3_157260663_157261197 0.34 C3orf55
 chromosome 3 open reading frame 55
 105
 0.98
chr12_122467875_122468026 0.34 BCL7A
 B-cell CLL/lymphoma 7A
 8158
 0.22
chr13_110958781_110959436 0.34 COL4A1
 collagen, type IV, alpha 1
 370
 0.6
chr11_119597594_119597745 0.33 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
 1594
 0.37
chr17_70120328_70120596 0.33 SOX9
 SRY (sex determining region Y)-box 9
 3301
 0.38
chr16_51184162_51184313 0.32 SALL1
 spalt-like transcription factor 1
 271
 0.87
chr22_44315340_44315603 0.32 PNPLA3
 patatin-like phospholipase domain containing 3
 4148
 0.18
chr22_43523181_43523332 0.31 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 15714
 0.13
chr12_46886554_46886705 0.31 SLC38A2
 solute carrier family 38, member 2
 119979
 0.06
chr16_67215217_67215453 0.31 KIAA0895L
 KIAA0895-like
 1370
 0.18
chr19_16936008_16936179 0.31 SIN3B
 SIN3 transcription regulator family member B
 4118
 0.16
chr11_61739742_61739933 0.30 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 4384
 0.15
chr8_11421540_11421831 0.30 RP11-148O21.2
4156
 0.18
chr1_186649638_186650434 0.30 PTGS2
 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
 477
 0.89
chr9_12775321_12775833 0.29 LURAP1L
 leucine rich adaptor protein 1-like
 557
 0.78
chr15_84116498_84116804 0.29 SH3GL3
 SH3-domain GRB2-like 3
 368
 0.92
chr16_69998972_69999655 0.29 CLEC18A
 C-type lectin domain family 18, member A
 13669
 0.14
chr22_30796002_30796153 0.29 SEC14L2
 SEC14-like 2 (S. cerevisiae)
 1511
 0.18
chr2_177001412_177001990 0.29 HOXD3
 homeobox D3
 16
 0.5
chr17_2310404_2311021 0.28 MNT
 MAX network transcriptional repressor
 6300
 0.12
chr10_62760865_62761099 0.28 RHOBTB1
 Rho-related BTB domain containing 1
 216
 0.97
chr1_31887122_31887273 0.28 SERINC2
 serine incorporator 2
 537
 0.74
chr13_107185066_107185426 0.28 EFNB2
 ephrin-B2
 2216
 0.4
chr2_165477169_165477439 0.27 GRB14
 growth factor receptor-bound protein 14
 684
 0.79
chr19_56166514_56167932 0.27 U2AF2
 U2 small nuclear RNA auxiliary factor 2
 792
 0.34
chr3_184300809_184300975 0.27 EPHB3
 EPH receptor B3
 21320
 0.18
chr17_75474006_75474173 0.27 SEPT9
 septin 9
 2764
 0.22
chr1_183236957_183237240 0.27 NMNAT2
 nicotinamide nucleotide adenylyltransferase 2
 36911
 0.19
chr11_61486524_61486808 0.26 MYRF
 myelin regulatory factor
 33455
 0.11
chr7_27225817_27225968 0.26 HOXA11-AS
 HOXA11 antisense RNA
 739
 0.31
chr4_151503456_151503607 0.26 MAB21L2
 mab-21-like 2 (C. elegans)
 454
 0.84
chr10_88728248_88728709 0.26 ADIRF
 adipogenesis regulatory factor
 289
 0.5
chr20_23031599_23032105 0.25 THBD
 thrombomodulin
 1474
 0.34
chr9_140506939_140507169 0.25 C9orf37
 chromosome 9 open reading frame 37
 6211
 0.12
chr8_128864051_128864244 0.25 ENSG00000249859
 .
 55939
 0.13
chr14_69015576_69015827 0.25 CTD-2325P2.4
79461
 0.1
chr2_75787048_75787447 0.25 EVA1A
 eva-1 homolog A (C. elegans)
 792
 0.61
chr8_99014292_99014443 0.25 MATN2
 matrilin 2
 14405
 0.15
chr17_79438730_79438973 0.25 RP11-1055B8.8
9888
 0.1
chr10_103330110_103330718 0.24 DPCD
 deleted in primary ciliary dyskinesia homolog (mouse)
 8
 0.98
chr5_112582093_112582348 0.24 MCC
 mutated in colorectal cancers
 11846
 0.27
chr19_5578062_5578357 0.24 SAFB2
 scaffold attachment factor B2
 44782
 0.11
chr2_127643626_127643777 0.24 AC114783.1
 Protein LOC339760
 12771
 0.28
chr3_71158955_71159120 0.24 FOXP1
 forkhead box P1
 20707
 0.28
chr9_81871858_81872685 0.24 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 314417
 0.01
chr1_32263785_32263971 0.24 SPOCD1
 SPOC domain containing 1
 439
 0.79
chr11_58730865_58731226 0.24 RP11-142C4.6
15713
 0.15
chr16_65155038_65155536 0.23 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 546
 0.88
chr3_114169976_114170457 0.23 ZBTB20
 zinc finger and BTB domain containing 20
 3314
 0.33
chr6_85484117_85484534 0.23 TBX18
 T-box 18
 10088
 0.3
chr15_96100470_96100831 0.23 ENSG00000222076
 .
 188383
 0.03
chrX_34675593_34676078 0.23 TMEM47
 transmembrane protein 47
 430
 0.92
chr17_45197869_45198099 0.23 ENSG00000221016
 .
 2116
 0.25
chr22_46933754_46934840 0.22 CELSR1
 cadherin, EGF LAG seven-pass G-type receptor 1
 1230
 0.46
chr15_75944753_75944922 0.22 SNX33
 sorting nexin 33
 2740
 0.14
chr12_124004050_124004201 0.22 RILPL1
 Rab interacting lysosomal protein-like 1
 5150
 0.17
chr2_202723535_202724043 0.22 ENSG00000221374
 .
 17937
 0.16
chr12_120032319_120032470 0.22 TMEM233
 transmembrane protein 233
 1130
 0.49
chr2_133173748_133173945 0.22 GPR39
 G protein-coupled receptor 39
 301
 0.92
chr8_42063953_42065062 0.22 PLAT
 plasminogen activator, tissue
 576
 0.71
chr9_134287538_134287689 0.21 PRRC2B
 proline-rich coiled-coil 2B
 17864
 0.19
chr11_89597318_89597927 0.21 TRIM64B
 tripartite motif containing 64B
 11563
 0.22
chr7_131240036_131240570 0.21 PODXL
 podocalyxin-like
 1063
 0.65
chr4_164265165_164265569 0.21 NPY5R
 neuropeptide Y receptor Y5
 113
 0.9
chr7_28997325_28997548 0.21 CTB-113D17.1
22147
 0.2
chr2_151343410_151343893 0.21 RND3
 Rho family GTPase 3
 530
 0.88
chr9_116356336_116356765 0.21 RGS3
 regulator of G-protein signaling 3
 784
 0.67
chr20_43970794_43971114 0.21 SDC4
 syndecan 4
 6110
 0.13
chr8_120879463_120879614 0.21 ENSG00000244642
 .
 4636
 0.17
chr14_58332211_58332467 0.21 SLC35F4
 solute carrier family 35, member F4
 441
 0.87
chr3_157155512_157155783 0.21 PTX3
 pentraxin 3, long
 1069
 0.63
chr3_66007529_66007703 0.20 MAGI1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 16367
 0.19
chr21_47394558_47394771 0.20 COL6A1
 collagen, type VI, alpha 1
 6987
 0.21
chr11_1896066_1896383 0.20 LSP1
 lymphocyte-specific protein 1
 1483
 0.24
chr16_2085550_2085759 0.20 SLC9A3R2
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
 2382
 0.09
chr7_64035084_64035528 0.20 ZNF680
 zinc finger protein 680
 11822
 0.28
chr1_2569102_2569253 0.20 MMEL1
 membrane metallo-endopeptidase-like 1
 4696
 0.16
chr15_68573802_68573977 0.20 FEM1B
 fem-1 homolog b (C. elegans)
 1592
 0.39
chr17_77997988_77998139 0.20 CTD-2529O21.2
333
 0.85
chr2_16832297_16832583 0.20 FAM49A
 family with sequence similarity 49, member A
 14656
 0.3
chr17_6922316_6922467 0.20 RP11-589P10.7
342
 0.53
chr18_57386327_57386692 0.20 CCBE1
 collagen and calcium binding EGF domains 1
 21897
 0.15
chr3_149094469_149095370 0.20 TM4SF1-AS1
 TM4SF1 antisense RNA 1
 646
 0.47
chr8_22443451_22443742 0.19 AC037459.4
 Uncharacterized protein
 3191
 0.12
chr12_26266071_26266589 0.19 SSPN
 sarcospan
 8594
 0.18
chr19_51455841_51455992 0.19 KLK5
 kallikrein-related peptidase 5
 282
 0.77
chr1_204042818_204043418 0.19 SOX13
 SRY (sex determining region Y)-box 13
 36
 0.98
chr6_4733420_4733615 0.19 CDYL
 chromodomain protein, Y-like
 27124
 0.2
chr20_48599552_48599945 0.19 SNAI1
 snail family zinc finger 1
 212
 0.92
chr12_96183320_96183471 0.19 NTN4
 netrin 4
 331
 0.86
chr2_36678228_36678401 0.19 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 62519
 0.12
chr19_41195400_41196566 0.19 NUMBL
 numb homolog (Drosophila)-like
 44
 0.96
chr4_57203544_57203695 0.19 ENSG00000251823
 .
 6236
 0.18
chr19_7953457_7953661 0.19 LRRC8E
 leucine rich repeat containing 8 family, member E
 123
 0.88
chr19_13983804_13984015 0.19 ENSG00000207613
 .
 1604
 0.17
chr13_110979643_110979794 0.19 COL4A2
 collagen, type IV, alpha 2
 20104
 0.2
chr3_44040787_44041403 0.18 ENSG00000252980
 .
 71484
 0.12
chr10_70359131_70359282 0.18 TET1
 tet methylcytosine dioxygenase 1
 38793
 0.13
chr17_75523143_75523294 0.18 SEPT9
 septin 9
 45223
 0.13
chr7_130131272_130131861 0.18 MEST
 mesoderm specific transcript
 368
 0.77
chr15_68580618_68580911 0.18 FEM1B
 fem-1 homolog b (C. elegans)
 829
 0.64
chr1_6556688_6556983 0.18 PLEKHG5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
 79
 0.95
chr11_833873_834149 0.18 CD151
 CD151 molecule (Raph blood group)
 861
 0.26
chr9_110513848_110514093 0.18 AL162389.1
 Uncharacterized protein
 26449
 0.19
chr17_75404849_75405000 0.18 SEPT9
 septin 9
 3765
 0.19
chr20_3657828_3657979 0.18 ADAM33
 ADAM metallopeptidase domain 33
 4847
 0.17
chr9_137445335_137445486 0.18 COL5A1
 collagen, type V, alpha 1
 88210
 0.08
chr20_43729394_43729952 0.18 KCNS1
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1
 77
 0.96
chr17_77752893_77753171 0.18 CBX2
 chromobox homolog 2
 1039
 0.43
chr12_47471040_47471191 0.17 PCED1B
 PC-esterase domain containing 1B
 2271
 0.31
chr1_150480831_150481087 0.17 ECM1
 extracellular matrix protein 1
 376
 0.77
chr6_28641788_28642196 0.17 ENSG00000272278
 .
 25950
 0.18
chr11_61159610_61160825 0.17 TMEM216
 transmembrane protein 216
 352
 0.79
chr16_70221940_70222878 0.17 CLEC18C
 C-type lectin domain family 18, member C
 14349
 0.1
chr9_137221469_137221673 0.17 RXRA
 retinoid X receptor, alpha
 3145
 0.33
chr5_140753330_140753954 0.17 PCDHGA6
 protocadherin gamma subfamily A, 6
 9
 0.91
chr12_6930752_6931082 0.17 GPR162
 G protein-coupled receptor 162
 47
 0.93
chr15_74344226_74344377 0.17 ENSG00000244612
 .
 20738
 0.13
chr17_77925559_77925739 0.17 TBC1D16
 TBC1 domain family, member 16
 163
 0.96
chr20_25565265_25566139 0.17 NINL
 ninein-like
 451
 0.81
chr12_132316928_132317093 0.17 MMP17
 matrix metallopeptidase 17 (membrane-inserted)
 3925
 0.2
chr17_74542570_74542721 0.17 RP11-666A8.7
3388
 0.1
chr16_51188825_51189552 0.17 SALL1
 spalt-like transcription factor 1
 4002
 0.28
chr11_43955270_43955437 0.17 C11orf96
 chromosome 11 open reading frame 96
 8461
 0.16
chr1_39569795_39569946 0.16 MACF1
 microtubule-actin crosslinking factor 1
 1213
 0.46
chr17_41909774_41910015 0.16 MPP3
 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
 284
 0.86
chr17_36902558_36902709 0.16 PCGF2
 polycomb group ring finger 2
 248
 0.78
chr1_67142291_67142442 0.16 AL139147.1
 Uncharacterized protein
 344
 0.88
chr22_32022509_32022660 0.16 PISD
 phosphatidylserine decarboxylase
 304
 0.91
chr20_10634629_10634907 0.16 JAG1
 jagged 1
 8386
 0.25
chr1_45082713_45082906 0.16 RNF220
 ring finger protein 220
 9189
 0.17
chr7_73245792_73245943 0.16 CLDN4
 claudin 4
 674
 0.63
chr15_40616235_40616987 0.16 LINC00984
 long intergenic non-protein coding RNA 984
 806
 0.39
chr16_4348992_4349159 0.16 GLIS2
 GLIS family zinc finger 2
 15687
 0.13
chr22_21311135_21311286 0.16 ENSG00000266366
 .
 1761
 0.2
chr9_695532_695683 0.16 RP11-130C19.3
10052
 0.22
chr14_100041328_100041479 0.16 CCDC85C
 coiled-coil domain containing 85C
 1526
 0.37
chr16_74440490_74441404 0.16 CLEC18B
 C-type lectin domain family 18, member B
 14343
 0.14
chr5_73770430_73770700 0.16 ENSG00000244326
 .
 156754
 0.04
chr7_5458775_5459294 0.15 AC093620.5
424
 0.46
chr16_31548902_31549248 0.15 AHSP
 alpha hemoglobin stabilizing protein
 9777
 0.11
chr3_48777290_48777441 0.15 PRKAR2A
 protein kinase, cAMP-dependent, regulatory, type II, alpha
 12386
 0.13
chr3_175244326_175245006 0.15 ENSG00000201648
 .
 82601
 0.1
chr11_393450_393735 0.15 PKP3
 plakophilin 3
 129
 0.92
chr4_125825441_125825711 0.15 ANKRD50
 ankyrin repeat domain 50
 191689
 0.03
chr17_68165729_68165994 0.15 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 185
 0.66
chr2_58655964_58656121 0.15 FANCL
 Fanconi anemia, complementation group L
 187535
 0.03
chr5_140762477_140762699 0.15 PCDHGA7
 protocadherin gamma subfamily A, 7
 121
 0.87
chr8_27491561_27492240 0.15 SCARA3
 scavenger receptor class A, member 3
 202
 0.93
chr1_40421563_40422081 0.15 MFSD2A
 major facilitator superfamily domain containing 2A
 1000
 0.48
chr22_19946584_19946980 0.15 COMT
 catechol-O-methyltransferase
 3288
 0.15
chr6_21886388_21886539 0.15 ENSG00000222515
 .
 199310
 0.03
chr11_63803897_63804159 0.15 RP11-21A7A.2
586
 0.65
chr2_151335102_151335779 0.15 RND3
 Rho family GTPase 3
 6456
 0.35
chr6_80656707_80657785 0.15 ELOVL4
 ELOVL fatty acid elongase 4
 51
 0.98
chr3_133967997_133968801 0.15 RYK
 receptor-like tyrosine kinase
 1038
 0.66
chr1_150480597_150480804 0.15 ECM1
 extracellular matrix protein 1
 117
 0.94
chrX_22153526_22153707 0.15 PHEX-AS1
 PHEX antisense RNA 1
 37484
 0.16
chr3_138957437_138957611 0.14 MRPS22
 mitochondrial ribosomal protein S22
 105337
 0.06
chr8_131503545_131503696 0.14 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 47714
 0.2
chr13_110959773_110960124 0.14 COL4A2
 collagen, type IV, alpha 2
 334
 0.6
chr5_14036568_14037099 0.14 DNAH5
 dynein, axonemal, heavy chain 5
 92181
 0.09
chr6_56716060_56716427 0.14 DST
 dystonin
 506
 0.82
chr14_23237291_23237442 0.14 OXA1L
 oxidase (cytochrome c) assembly 1-like
 1438
 0.23
chr1_156718751_156718902 0.14 HDGF
 hepatoma-derived growth factor
 2259
 0.16
chr20_4129930_4130735 0.14 SMOX
 spermine oxidase
 750
 0.71
chr1_223921059_223921210 0.14 CAPN2
 calpain 2, (m/II) large subunit
 21100
 0.19
chr14_55121110_55121261 0.14 SAMD4A
 sterile alpha motif domain containing 4A
 86548
 0.09
chr16_4424352_4424847 0.14 VASN
 vasorin
 2750
 0.17
chr8_54789629_54790008 0.14 RP11-1070A24.2
609
 0.71
chr13_36705915_36706066 0.14 DCLK1
 doublecortin-like kinase 1
 547
 0.84
chr3_122786767_122787219 0.14 PDIA5
 protein disulfide isomerase family A, member 5
 798
 0.71
chr1_209603784_209603935 0.14 ENSG00000230937
 .
 1619
 0.52
chr19_47163250_47163584 0.14 DACT3-AS1
 DACT3 antisense RNA 1
 204
 0.83
chrX_153601896_153602918 0.14 FLNA
 filamin A, alpha
 587
 0.54
chr13_72440002_72440456 0.14 DACH1
 dachshund homolog 1 (Drosophila)
 678
 0.82
chr13_110972530_110972681 0.14 COL4A2
 collagen, type IV, alpha 2
 12991
 0.21
chr12_109901272_109901510 0.14 KCTD10
 potassium channel tetramerization domain containing 10
 3191
 0.21
chr14_78447028_78447687 0.14 ENSG00000199440
 .
 159872
 0.03
chr11_45922009_45922186 0.14 MAPK8IP1
 mitogen-activated protein kinase 8 interacting protein 1
 3996
 0.14
chr2_236578616_236578898 0.14 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 509
 0.87
chr17_77767116_77767731 0.14 CBX8
 chromobox homolog 8
 3492
 0.16

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of GLIS3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.4 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.2 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.2 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0044803 multi-organism membrane organization(GO:0044803)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0046958 nonassociative learning(GO:0046958)
0.0 0.2 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.0 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0015904 tetracycline transport(GO:0015904)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0070306 lens fiber cell differentiation(GO:0070306)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.3 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.0 GO:0043159 acrosomal matrix(GO:0043159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.3 GO:0043236 laminin binding(GO:0043236)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0015520 tetracycline:proton antiporter activity(GO:0015520)
0.0 0.1 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0042806 fucose binding(GO:0042806)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.0 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions