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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GRHL1

Z-value: 1.36

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Transcription factors associated with GRHL1

Gene Symbol	Gene ID	Gene Info
GRHL1 Ensembl NCBI GeneCards UniProt	ENSG00000134317.13	GRHL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GRHL1	chr2_10091040_10091475	535	0.791189	0.91	6.9e-04	Click!
GRHL1	chr2_10090883_10091034	834	0.639056	0.82	6.2e-03	Click!
GRHL1	chr2_10090679_10090830	1038	0.553917	0.81	8.5e-03	Click!
GRHL1	chr2_10091778_10091990	57	0.977081	0.77	1.6e-02	Click!
GRHL1	chr2_10124648_10124876	10672	0.165414	0.51	1.6e-01	Click!

Activity of the GRHL1 motif across conditions

Conditions sorted by the z-value of the GRHL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_34626880_34627184	0.70	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	2013	0.2
chr2_10091778_10091990	0.62	GRHL1	grainyhead-like 1 (Drosophila)	57	0.98
chr1_147142364_147142605	0.62	ACP6	acid phosphatase 6, lysophosphatidic	120	0.97
chr8_81262205_81262356	0.58	ENSG00000206649	.	32976	0.18
chr21_46493485_46493673	0.58	AP001579.1	Uncharacterized protein	652	0.5
chr11_104838069_104839428	0.57	CASP4	caspase 4, apoptosis-related cysteine peptidase	1345	0.45
chr10_31321494_31321708	0.56	ZNF438	zinc finger protein 438	735	0.75
chr6_108497000_108497194	0.55	NR2E1	nuclear receptor subfamily 2, group E, member 1	7130	0.18
chr14_99734743_99735157	0.54	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	2615	0.3
chr7_100487833_100488038	0.54	UFSP1	UFM1-specific peptidase 1 (non-functional)	596	0.54
chr9_140121732_140121883	0.53	RNF224	ring finger protein 224	211	0.78
chr19_1491435_1491715	0.51	REEP6	receptor accessory protein 6	410	0.58
chr16_433636_433787	0.51	TMEM8A	transmembrane protein 8A	1729	0.2
chr3_128444656_128444807	0.51	RAB7A	RAB7A, member RAS oncogene family	234	0.92
chr7_69946018_69946169	0.47	AUTS2	autism susceptibility candidate 2	248032	0.02
chr17_71087973_71088223	0.47	SLC39A11	solute carrier family 39, member 11	717	0.75
chr1_206732914_206733127	0.47	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	2527	0.25
chr6_159084795_159085026	0.47	SYTL3	synaptotagmin-like 3	715	0.68
chr8_24151584_24151953	0.46	ADAM28	ADAM metallopeptidase domain 28	144	0.97
chr16_72236428_72236579	0.46	PMFBP1	polyamine modulated factor 1 binding protein 1	25726	0.19
chr5_126147731_126147991	0.46	LMNB1	lamin B1	34980	0.19
chr5_141016577_141016949	0.45	RELL2	RELT-like 2	170	0.67
chr8_28558312_28558856	0.43	EXTL3-AS1	EXTL3 antisense RNA 1	186	0.6
chrX_119602028_119603217	0.43	LAMP2	lysosomal-associated membrane protein 2	225	0.95
chr3_172240144_172241280	0.42	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	553	0.83
chr1_44016013_44016164	0.42	PTPRF	protein tyrosine phosphatase, receptor type, F	5341	0.22
chr17_77788750_77788949	0.41	ENSG00000238331	.	4371	0.16
chr12_54376113_54376277	0.41	HOXC-AS3	HOXC cluster antisense RNA 3	1913	0.11
chr7_39989218_39989369	0.41	RP11-467D6.1		61	0.83
chr16_1582253_1582404	0.40	IFT140	intraflagellar transport 140 homolog (Chlamydomonas)	1167	0.25
chr2_158297089_158297418	0.40	ENSG00000216054	.	809	0.56
chr9_4662590_4663079	0.40	PPAPDC2	phosphatidic acid phosphatase type 2 domain containing 2	536	0.74
chr4_89534455_89534711	0.39	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	7638	0.19
chr3_182986311_182986462	0.38	B3GNT5	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5	3254	0.26
chr1_150976711_150976969	0.38	FAM63A	family with sequence similarity 63, member A	2121	0.14
chr8_38215915_38216066	0.38	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	22349	0.11
chr9_133031265_133031416	0.37	HMCN2	hemicentin 2	15542	0.23
chr2_52954585_52954736	0.37	ENSG00000264975	.	24907	0.29
chr7_100183497_100183687	0.37	LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4	184	0.64
chr18_39534653_39534946	0.36	PIK3C3	phosphatidylinositol 3-kinase, catalytic subunit type 3	372	0.93
chr1_29066884_29067035	0.36	YTHDF2	YTH domain family, member 2	3482	0.22
chr1_12240704_12240855	0.36	ENSG00000263676	.	10991	0.15
chr22_20424024_20424175	0.36	ENSG00000271796	.	10054	0.12
chr5_173665504_173665655	0.35	CTC-229L21.1		65475	0.14
chr17_18265908_18266237	0.35	SHMT1	serine hydroxymethyltransferase 1 (soluble)	588	0.63
chrX_97323503_97323654	0.34	DIAPH2-AS1	DIAPH2 antisense RNA 1	425990	0.01
chr21_35305474_35305968	0.34	LINC00649	long intergenic non-protein coding RNA 649	2203	0.25
chr17_55434039_55434190	0.33	ENSG00000263902	.	55448	0.13
chr13_111364022_111364765	0.33	ING1	inhibitor of growth family, member 1	690	0.72
chr2_113592071_113592291	0.33	IL1B	interleukin 1, beta	1830	0.31
chr19_40030594_40030834	0.33	EID2	EP300 interacting inhibitor of differentiation 2	156	0.91
chr8_142231340_142231491	0.33	SLC45A4	solute carrier family 45, member 4	7254	0.16
chr4_154388914_154389185	0.33	KIAA0922	KIAA0922	1548	0.49
chr1_25060751_25060902	0.32	CLIC4	chloride intracellular channel 4	11022	0.2
chr11_62572291_62572857	0.32	NXF1	nuclear RNA export factor 1	91	0.89
chr13_41540610_41540946	0.32	ELF1	E74-like factor 1 (ets domain transcription factor)	15640	0.18
chr18_29021056_29021207	0.32	DSG3	desmoglein 3	6627	0.17
chr22_21775304_21775479	0.31	HIC2	hypermethylated in cancer 2	466	0.71
chr2_85640695_85641186	0.31	CAPG	capping protein (actin filament), gelsolin-like	222	0.85
chr8_96150063_96150319	0.31	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	3887	0.25
chr12_48099956_48100625	0.31	RPAP3	RNA polymerase II associated protein 3	446	0.81
chr16_73031152_73031303	0.31	ENSG00000221799	.	12471	0.2
chr9_37030099_37030250	0.31	PAX5	paired box 5	3854	0.25
chr1_159870035_159870397	0.31	CCDC19	coiled-coil domain containing 19	263	0.55
chr12_120667761_120668330	0.31	PXN	paxillin	3398	0.15
chr3_149956404_149956555	0.31	RP11-167H9.4		140660	0.04
chr6_116797520_116797797	0.31	RP1-93H18.6		12803	0.11
chr16_4818256_4818411	0.31	ZNF500	zinc finger protein 500	708	0.52
chr18_9018040_9018191	0.31	NDUFV2	NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa	84513	0.08
chr2_109236287_109236438	0.30	LIMS1	LIM and senescent cell antigen-like domains 1	1360	0.51
chr22_36769485_36769706	0.30	MYH9	myosin, heavy chain 9, non-muscle	8438	0.19
chr13_106996229_106996778	0.30	ENSG00000222682	.	188664	0.03
chr3_69139558_69139806	0.30	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5	5510	0.16
chr10_75815554_75815957	0.30	VCL	vinculin	27479	0.17
chr6_35265630_35266434	0.30	DEF6	differentially expressed in FDCP 6 homolog (mouse)	403	0.84
chr7_151548013_151548400	0.30	PRKAG2-AS1	PRKAG2 antisense RNA 1	25921	0.14
chr12_30848459_30848714	0.30	IPO8	importin 8	334	0.92
chr2_241832903_241833054	0.30	C2orf54	chromosome 2 open reading frame 54	1523	0.34
chr12_64798382_64799443	0.29	XPOT	exportin, tRNA	86	0.97
chr14_68431244_68431431	0.29	RAD51B	RAD51 paralog B	141076	0.04
chr18_72166510_72167447	0.29	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	118	0.97
chr11_46141542_46141818	0.29	PHF21A	PHD finger protein 21A	267	0.92
chr17_7834732_7835241	0.29	TRAPPC1	trafficking protein particle complex 1	277	0.58
chr8_17293592_17293743	0.29	MTMR7	myotubularin related protein 7	22831	0.22
chr12_102454924_102455862	0.29	CCDC53	coiled-coil domain containing 53	464	0.76
chr1_51426093_51426543	0.29	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	99	0.82
chr19_1795974_1796208	0.29	ATP8B3	ATPase, aminophospholipid transporter, class I, type 8B, member 3	15532	0.09
chr18_12839173_12839633	0.28	PTPN2	protein tyrosine phosphatase, non-receptor type 2	2580	0.33
chr2_69004074_69004225	0.28	ARHGAP25	Rho GTPase activating protein 25	2077	0.39
chr20_57431129_57431280	0.28	GNAS	GNAS complex locus	971	0.45
chr18_45834501_45834652	0.28	ZBTB7C	zinc finger and BTB domain containing 7C	30186	0.19
chr13_98084501_98085278	0.27	RAP2A	RAP2A, member of RAS oncogene family	1587	0.5
chr6_25963703_25964110	0.27	TRIM38	tripartite motif containing 38	631	0.58
chr17_58228097_58228436	0.27	CA4	carbonic anhydrase IV	963	0.55
chr12_120907252_120907411	0.27	SRSF9	serine/arginine-rich splicing factor 9	43	0.8
chr19_15435123_15435274	0.27	BRD4	bromodomain containing 4	7519	0.18
chr9_131534376_131534797	0.27	ZER1	zyg-11 related, cell cycle regulator	107	0.94
chr5_112257522_112257903	0.26	REEP5	receptor accessory protein 5	18	0.97
chr9_95570304_95570464	0.26	ANKRD19P	ankyrin repeat domain 19, pseudogene	1509	0.37
chr2_201991504_201992128	0.26	CFLAR	CASP8 and FADD-like apoptosis regulator	2236	0.22
chr6_24666286_24667027	0.26	TDP2	tyrosyl-DNA phosphodiesterase 2	163	0.84
chr16_23568244_23568679	0.26	UBFD1	ubiquitin family domain containing 1	69	0.68
chr18_44496350_44497016	0.26	PIAS2	protein inhibitor of activated STAT, 2	359	0.71
chr12_106751930_106752216	0.25	POLR3B	polymerase (RNA) III (DNA directed) polypeptide B	213	0.95
chr22_21274799_21275119	0.25	CRKL	v-crk avian sarcoma virus CT10 oncogene homolog-like	3245	0.15
chr20_45986315_45986612	0.25	ZMYND8	zinc finger, MYND-type containing 8	896	0.5
chrX_2815751_2815902	0.25	ARSD-AS1	ARSD antisense RNA 1	7119	0.17
chr17_47335011_47335162	0.25	PHOSPHO1	phosphatase, orphan 1	26958	0.13
chr14_22192285_22192436	0.25	ENSG00000222776	.	56425	0.12
chr19_13209170_13209477	0.25	LYL1	lymphoblastic leukemia derived sequence 1	4358	0.12
chr20_56861857_56862008	0.25	PPP4R1L	protein phosphatase 4, regulatory subunit 1-like	22563	0.18
chr19_40596081_40597156	0.25	AC005614.3		43	0.64
chrX_111214548_111214699	0.25	TRPC5OS	TRPC5 opposite strand	89498	0.09
chrX_40027620_40027771	0.25	BCOR	BCL6 corepressor	8878	0.31
chr16_74481592_74481743	0.24	ENSG00000251794	.	8772	0.15
chr14_51403011_51403162	0.24	PYGL	phosphorylase, glycogen, liver	8088	0.19
chr5_134094525_134094724	0.24	DDX46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46	130	0.95
chr6_16130421_16130915	0.24	MYLIP	myosin regulatory light chain interacting protein	1266	0.45
chr10_50626942_50627093	0.24	RP11-123B3.2		306	0.9
chr12_54018173_54018459	0.24	ATF7	activating transcription factor 7	1439	0.29
chr22_46436516_46436667	0.24	RP6-109B7.5		12382	0.1
chr19_34663821_34664709	0.24	LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)	702	0.77
chr1_149711963_149712172	0.24	ENSG00000263825	.	3116	0.14
chr5_176786759_176786924	0.24	RGS14	regulator of G-protein signaling 14	2003	0.18
chr3_182513059_182513572	0.23	ATP11B	ATPase, class VI, type 11B	2024	0.32
chr16_23782392_23782543	0.23	CHP2	calcineurin-like EF-hand protein 2	16519	0.17
chr16_3414793_3414984	0.23	MTRNR2L4	MT-RNR2-like 4	7395	0.11
chr9_132514519_132514800	0.23	PTGES	prostaglandin E synthase	667	0.66
chr1_193154702_193155811	0.23	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	528	0.8
chr10_55884978_55885129	0.23	ENSG00000263921	.	222721	0.02
chr2_213880427_213880578	0.22	AC079610.1		5767	0.31
chr8_42748827_42749465	0.22	ENSG00000266044	.	2272	0.19
chr9_77641918_77642364	0.22	C9orf41	chromosome 9 open reading frame 41	126	0.96
chr11_113433650_113433801	0.22	DRD2	dopamine receptor D2	87614	0.08
chr13_20805734_20806347	0.22	GJB6	gap junction protein, beta 6, 30kDa	400	0.87
chr12_1313659_1314218	0.22	ERC1	ELKS/RAB6-interacting/CAST family member 1	177000	0.03
chr12_15039325_15039476	0.22	MGP	matrix Gla protein	540	0.72
chr1_6532288_6532439	0.22	TNFRSF25	tumor necrosis factor receptor superfamily, member 25	6108	0.12
chr1_151030627_151031763	0.22	CDC42SE1	CDC42 small effector 1	930	0.27
chr2_191183369_191183553	0.22	HIBCH	3-hydroxyisobutyryl-CoA hydrolase	1155	0.54
chr17_18091438_18091835	0.22	RP11-258F1.1		3569	0.14
chr1_114888713_114889187	0.21	TRIM33	tripartite motif containing 33	116908	0.06
chr8_71126242_71126393	0.21	NCOA2	nuclear receptor coactivator 2	31293	0.22
chr14_59655511_59655710	0.21	DAAM1	dishevelled associated activator of morphogenesis 1	193	0.97
chr10_64134972_64135123	0.21	ZNF365	zinc finger protein 365	256	0.94
chr1_38454967_38455422	0.21	SF3A3	splicing factor 3a, subunit 3, 60kDa	465	0.7
chr19_6669496_6669799	0.21	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	481	0.75
chr16_58843484_58843635	0.21	ENSG00000244003	.	39131	0.16
chr16_49561945_49562197	0.21	ZNF423	zinc finger protein 423	112692	0.06
chr17_4711251_4711402	0.21	PLD2	phospholipase D2	469	0.63
chr1_70670699_70671189	0.21	LRRC40	leucine rich repeat containing 40	359	0.53
chrX_11777788_11778628	0.21	MSL3	male-specific lethal 3 homolog (Drosophila)	461	0.9
chr3_16883621_16883873	0.21	PLCL2	phospholipase C-like 2	42705	0.19
chr10_99168347_99168498	0.21	RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	7295	0.1
chr6_28907953_28908476	0.21	C6orf100	chromosome 6 open reading frame 100	3440	0.16
chrX_52004796_52004996	0.21	RP11-363G10.2		61933	0.11
chr19_2042439_2042863	0.20	MKNK2	MAP kinase interacting serine/threonine kinase 2	19	0.96
chr9_125011063_125011347	0.20	ENSG00000272317	.	7007	0.13
chr1_249152113_249152387	0.20	ZNF692	zinc finger protein 692	809	0.43
chr14_70161423_70161574	0.20	SRSF5	serine/arginine-rich splicing factor 5	32119	0.19
chr11_72492321_72492601	0.20	STARD10	StAR-related lipid transfer (START) domain containing 10	419	0.73
chr2_37880790_37881166	0.20	CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	6177	0.28
chrX_70329371_70329522	0.20	IL2RG	interleukin 2 receptor, gamma	328	0.79
chr1_75196025_75196269	0.20	CRYZ	crystallin, zeta (quinone reductase)	2348	0.29
chr1_68215148_68215597	0.20	ENSG00000238778	.	22964	0.2
chr17_143390_143541	0.20	RP11-1260E13.1		27718	0.13
chr17_33412938_33413089	0.20	RFFL	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	2841	0.14
chr1_210406047_210406239	0.20	SERTAD4	SERTA domain containing 4	1	0.69
chr2_101729475_101729669	0.20	ENSG00000265860	.	19541	0.19
chr7_134832844_134833492	0.20	AC083862.1	Uncharacterized protein	252	0.58
chr4_107227768_107227919	0.20	TBCK	TBC1 domain containing kinase	3902	0.28
chr9_77703527_77704915	0.20	OSTF1	osteoclast stimulating factor 1	762	0.5
chrX_65217747_65217898	0.20	RP6-159A1.3		1771	0.4
chr2_102314830_102315631	0.20	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	238	0.96
chr6_47009797_47009948	0.20	GPR110	G protein-coupled receptor 110	158	0.97
chr10_52176688_52176970	0.20	AC069547.2	Uncharacterized protein	24063	0.19
chr10_75011688_75012124	0.19	MRPS16	mitochondrial ribosomal protein S16	484	0.47
chr16_2588059_2588223	0.19	PDPK1	3-phosphoinositide dependent protein kinase-1	24	0.92
chr9_5450042_5450535	0.19	CD274	CD274 molecule	215	0.94
chr5_176800994_176801145	0.19	SLC34A1	solute carrier family 34 (type II sodium/phosphate contransporter), member 1	5167	0.1
chr15_71740308_71740459	0.19	ENSG00000252813	.	27443	0.23
chr15_66679290_66679512	0.19	MAP2K1	mitogen-activated protein kinase kinase 1	246	0.56
chr11_26604890_26605185	0.19	MUC15	mucin 15, cell surface associated	11257	0.3
chr19_3163912_3164063	0.19	AC005264.2		8814	0.11
chr15_40366035_40366186	0.19	RP11-521C20.3		14923	0.14
chr22_43330177_43330519	0.19	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	11531	0.23
chr6_153323257_153323895	0.19	MTRF1L	mitochondrial translational release factor 1-like	244	0.91
chr9_84301810_84302157	0.19	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	300	0.93
chr19_53700941_53701337	0.19	ZNF665	zinc finger protein 665	4512	0.14
chr10_126410360_126410511	0.19	FAM53B-AS1	FAM53B antisense RNA 1	17682	0.16
chr2_74433191_74433522	0.18	MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	7613	0.14
chr17_46048416_46049087	0.18	CDK5RAP3	CDK5 regulatory subunit associated protein 3	234	0.85
chr2_46542537_46542756	0.18	EPAS1	endothelial PAS domain protein 1	18105	0.25
chr17_53829632_53829783	0.18	PCTP	phosphatidylcholine transfer protein	946	0.66
chr12_88429328_88429956	0.18	C12orf29	chromosome 12 open reading frame 29	419	0.84
chr11_77113473_77113624	0.18	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	9401	0.24
chr15_82648106_82648257	0.18	GOLGA6L10	golgin A6 family-like 10	6475	0.18
chr12_120912385_120912536	0.18	DYNLL1	dynein, light chain, LC8-type 1	4774	0.11
chr12_52611181_52611332	0.18	KRT7	keratin 7	15642	0.1
chr8_29206404_29207399	0.18	DUSP4	dual specificity phosphatase 4	579	0.71

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GRHL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.2	GO:0006565	L-serine catabolic process(GO:0006565)
0.1	0.3	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.2	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1	0.3	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.1	0.3	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.1	0.2	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.1	0.2	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0031061	negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.1	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.0	GO:1903312	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.3	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0032431	activation of phospholipase A2 activity(GO:0032431)
0.0	0.5	GO:0007032	endosome organization(GO:0007032)
0.0	0.2	GO:0016556	mRNA modification(GO:0016556)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.2	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.1	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.3	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.0	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0051299	centrosome separation(GO:0051299)
0.0	0.1	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.2	GO:0050775	positive regulation of dendrite morphogenesis(GO:0050775)
0.0	0.1	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.4	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.1	GO:1901224	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.0	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.1	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.0	0.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.4	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0097035	regulation of membrane lipid distribution(GO:0097035)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.2	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.2	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.0	GO:0002335	mature B cell differentiation involved in immune response(GO:0002313) mature B cell differentiation(GO:0002335)
0.0	0.1	GO:0046719	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0060346	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0072487	MSL complex(GO:0072487)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.3	GO:0042405	nuclear inclusion body(GO:0042405)
0.1	0.2	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.5	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.4	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0051233	spindle midzone(GO:0051233)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:0000791	euchromatin(GO:0000791)
0.0	0.7	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0005844	polysome(GO:0005844)
0.0	0.1	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	0.1	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.2	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.6	GO:0003993	acid phosphatase activity(GO:0003993)
0.1	0.2	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.2	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	0.2	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.4	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.2	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.3	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0004516	nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0	0.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.5	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0000049	tRNA binding(GO:0000049)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.4	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.4	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.0	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.5	GO:0016876	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0	0.0	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.4	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.7	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.0	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.7	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.2	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	PID ALK1 PATHWAY	ALK1 signaling events
0.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.2	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.3	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.2	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.2	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly