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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for GSC_GSC2

Z-value: 0.75

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Transcription factors associated with GSC_GSC2

Gene Symbol	Gene ID	Gene Info
GSC Ensembl NCBI GeneCards UniProt	ENSG00000133937.3	GSC
GSC2 Ensembl NCBI GeneCards UniProt	ENSG00000063515.2	GSC2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
GSC	chr14_95363694_95363845	127207	0.051511	-0.85	3.8e-03	Click!
GSC	chr14_95218837_95218988	17650	0.246162	-0.59	9.4e-02	Click!
GSC	chr14_95242002_95242153	5515	0.300144	-0.52	1.6e-01	Click!
GSC	chr14_95402811_95402962	166324	0.032050	-0.45	2.2e-01	Click!
GSC	chr14_95236319_95236561	122	0.978358	0.41	2.8e-01	Click!
GSC2	chr22_19136719_19137042	916	0.414342	0.81	7.8e-03	Click!
GSC2	chr22_19137054_19137376	581	0.606263	0.68	4.4e-02	Click!
GSC2	chr22_19138892_19139181	1240	0.310193	0.43	2.5e-01	Click!

Activity of the GSC_GSC2 motif across conditions

Conditions sorted by the z-value of the GSC_GSC2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_128383033_128383215	0.46	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	7835	0.24
chr4_109083741_109084005	0.40	LEF1	lymphoid enhancer-binding factor 1	3584	0.27
chr17_73522364_73522644	0.39	LLGL2	lethal giant larvae homolog 2 (Drosophila)	634	0.56
chr1_198610531_198610895	0.38	PTPRC	protein tyrosine phosphatase, receptor type, C	2421	0.36
chr19_48752565_48752795	0.34	CARD8	caspase recruitment domain family, member 8	245	0.88
chr16_27415626_27415898	0.34	IL21R	interleukin 21 receptor	1339	0.47
chr12_122729504_122729668	0.33	VPS33A	vacuolar protein sorting 33 homolog A (S. cerevisiae)	5126	0.17
chr12_47606378_47606570	0.32	PCED1B	PC-esterase domain containing 1B	3578	0.27
chr20_43597121_43597440	0.31	STK4	serine/threonine kinase 4	2113	0.25
chr1_226922484_226922931	0.31	ITPKB	inositol-trisphosphate 3-kinase B	2452	0.34
chr11_66314663_66314814	0.30	ZDHHC24	zinc finger, DHHC-type containing 24	1029	0.34
chr14_22952184_22952433	0.29	ENSG00000251002	.	360	0.73
chr4_40200858_40201138	0.28	RHOH	ras homolog family member H	966	0.6
chr2_113931904_113932161	0.28	PSD4	pleckstrin and Sec7 domain containing 4	458	0.63
chr3_16329620_16329771	0.27	OXNAD1	oxidoreductase NAD-binding domain containing 1	18947	0.15
chr12_51713121_51713481	0.27	BIN2	bridging integrator 2	4598	0.18
chr2_192540821_192541028	0.27	NABP1	nucleic acid binding protein 1	1938	0.47
chr12_109254375_109254526	0.27	DAO	D-amino-acid oxidase	1742	0.29
chrX_21676275_21676631	0.26	KLHL34	kelch-like family member 34	5	0.99
chr3_60066334_60066485	0.26	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	108826	0.08
chrX_12991784_12992037	0.26	TMSB4X	thymosin beta 4, X-linked	1317	0.51
chr19_6425433_6425584	0.26	KHSRP	KH-type splicing regulatory protein	703	0.46
chr12_4381475_4382675	0.25	CCND2	cyclin D2	863	0.52
chr1_25889390_25889576	0.25	LDLRAP1	low density lipoprotein receptor adaptor protein 1	19412	0.19
chr4_3304601_3305007	0.25	RGS12	regulator of G-protein signaling 12	5958	0.26
chr9_469822_470055	0.25	RP11-165F24.3		102	0.79
chr5_134879321_134879990	0.24	NEUROG1	neurogenin 1	8016	0.18
chr14_22466666_22466817	0.24	ENSG00000238634	.	144146	0.04
chr12_103889282_103889433	0.24	C12orf42	chromosome 12 open reading frame 42	374	0.91
chr3_63953694_63954206	0.24	ATXN7	ataxin 7	530	0.74
chr13_41372571_41372761	0.24	SLC25A15	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15	5372	0.18
chr11_104904746_104905919	0.24	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr22_40304150_40304385	0.24	GRAP2	GRB2-related adaptor protein 2	7154	0.18
chr14_100544647_100544798	0.23	CTD-2376I20.1		3507	0.18
chrX_48771508_48771659	0.23	PIM2	pim-2 oncogene	1429	0.23
chr13_68203141_68203292	0.23	PCDH9	protocadherin 9	398748	0.01
chr15_40599321_40599893	0.23	PLCB2	phospholipase C, beta 2	419	0.68
chr19_35630816_35630967	0.23	FXYD1	FXYD domain containing ion transport regulator 1	35	0.95
chrX_11780001_11780185	0.23	MSL3	male-specific lethal 3 homolog (Drosophila)	2346	0.44
chr6_32160504_32160787	0.23	GPSM3	G-protein signaling modulator 3	0	0.94
chr20_34331618_34331769	0.23	RBM39	RNA binding motif protein 39	1459	0.29
chr5_141062081_141062481	0.23	ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	493	0.75
chr2_175459196_175459684	0.22	WIPF1	WAS/WASL interacting protein family, member 1	3053	0.24
chr1_117299964_117300188	0.22	CD2	CD2 molecule	2987	0.29
chr14_22204676_22204903	0.22	ENSG00000222776	.	43996	0.15
chr13_40532306_40532606	0.22	ENSG00000212553	.	101092	0.08
chr3_112217855_112218341	0.22	BTLA	B and T lymphocyte associated	107	0.98
chr6_128239129_128239316	0.22	THEMIS	thymocyte selection associated	463	0.89
chr4_26886197_26886348	0.22	STIM2	stromal interaction molecule 2	23191	0.22
chr17_38019635_38019786	0.22	IKZF3	IKAROS family zinc finger 3 (Aiolos)	669	0.62
chr20_42360174_42360325	0.22	GTSF1L	gametocyte specific factor 1-like	4611	0.26
chr2_198173822_198174153	0.22	ANKRD44	ankyrin repeat domain 44	1524	0.32
chr4_81106153_81106599	0.21	PRDM8	PR domain containing 8	48	0.98
chr15_80262648_80263745	0.21	BCL2A1	BCL2-related protein A1	315	0.89
chr2_27487055_27487432	0.21	SLC30A3	solute carrier family 30 (zinc transporter), member 3	239	0.85
chr16_3627461_3627612	0.21	NLRC3	NLR family, CARD domain containing 3	135	0.95
chr5_159713959_159714110	0.21	ENSG00000243654	.	4761	0.2
chr3_113250860_113251011	0.21	SIDT1	SID1 transmembrane family, member 1	208	0.94
chr18_56326442_56326593	0.21	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	12101	0.14
chr20_61438769_61438978	0.21	OGFR	opioid growth factor receptor	248	0.85
chr10_70362033_70362257	0.21	TET1	tet methylcytosine dioxygenase 1	41732	0.13
chr15_100890052_100890414	0.21	ADAMTS17	ADAM metallopeptidase with thrombospondin type 1 motif, 17	8023	0.23
chr8_134509504_134509655	0.20	ST3GAL1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	2025	0.48
chr14_22203899_22204050	0.20	ENSG00000222776	.	44811	0.15
chr16_67970526_67970748	0.20	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	353	0.73
chr6_106969857_106970345	0.20	AIM1	absent in melanoma 1	10371	0.2
chr19_53496276_53496464	0.20	ERVV-1	endogenous retrovirus group V, member 1	20804	0.13
chr16_85769625_85769776	0.20	ENSG00000222190	.	5606	0.13
chr10_14612285_14612533	0.20	FAM107B	family with sequence similarity 107, member B	1620	0.47
chr14_22989269_22989534	0.20	TRAJ15	T cell receptor alpha joining 15	9179	0.11
chr6_154568354_154568864	0.19	IPCEF1	interaction protein for cytohesin exchange factors 1	53	0.99
chr14_22739869_22740020	0.19	ENSG00000238634	.	129057	0.04
chr4_69433676_69433827	0.19	UGT2B17	UDP glucuronosyltransferase 2 family, polypeptide B17	494	0.87
chr14_94543541_94543837	0.19	DDX24	DEAD (Asp-Glu-Ala-Asp) box helicase 24	3859	0.17
chr14_61814123_61814302	0.19	PRKCH	protein kinase C, eta	397	0.87
chr7_36327271_36327770	0.19	EEPD1	endonuclease/exonuclease/phosphatase family domain containing 1	9233	0.18
chr21_35306376_35306527	0.19	LINC00649	long intergenic non-protein coding RNA 649	2933	0.21
chr5_40684385_40684698	0.19	PTGER4	prostaglandin E receptor 4 (subtype EP4)	4941	0.23
chr8_100714756_100715301	0.19	ENSG00000243254	.	88722	0.08
chr4_149367147_149367363	0.19	NR3C2	nuclear receptor subfamily 3, group C, member 2	1405	0.59
chr1_25260510_25260661	0.19	RUNX3	runt-related transcription factor 3	4217	0.26
chr1_66800579_66801197	0.19	PDE4B	phosphodiesterase 4B, cAMP-specific	3016	0.39
chr4_40240088_40240239	0.18	RHOH	ras homolog family member H	38199	0.16
chr10_120891057_120891670	0.18	FAM45A	family with sequence similarity 45, member A	27734	0.11
chr6_37104092_37104243	0.18	PIM1	pim-1 oncogene	33812	0.15
chr6_2902163_2902328	0.18	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	1269	0.44
chr3_72788121_72788360	0.18	ENSG00000222838	.	47278	0.17
chr1_155146016_155146243	0.18	TRIM46	tripartite motif containing 46	225	0.54
chr11_108099098_108099249	0.18	ENSG00000206967	.	1158	0.42
chr8_65607910_65608061	0.18	RP11-1D12.1		39031	0.2
chr2_238581678_238581829	0.18	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	19035	0.2
chr1_202612976_202613127	0.18	SYT2	synaptotagmin II	470	0.84
chr5_118623311_118623849	0.18	ENSG00000243333	.	18746	0.17
chr13_99951513_99951834	0.18	GPR183	G protein-coupled receptor 183	7986	0.2
chrX_44203680_44203969	0.18	EFHC2	EF-hand domain (C-terminal) containing 2	906	0.71
chr11_133814931_133815363	0.18	IGSF9B	immunoglobulin superfamily, member 9B	1040	0.55
chr6_139461625_139461834	0.18	HECA	headcase homolog (Drosophila)	5480	0.28
chr7_38315629_38315780	0.18	STARD3NL	STARD3 N-terminal like	97707	0.09
chr11_104787850_104788088	0.18	RP11-693N9.2		7327	0.2
chr9_132402475_132402626	0.18	RP11-483H20.4		205	0.89
chr1_154324818_154325020	0.18	ENSG00000238365	.	13700	0.1
chr2_240188602_240189192	0.17	ENSG00000265215	.	38260	0.14
chr22_51059908_51060313	0.17	ARSA	arylsulfatase A	6473	0.1
chr11_128372497_128372648	0.17	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	2717	0.34
chr14_23015065_23015417	0.17	AE000662.92	Uncharacterized protein	10293	0.11
chr1_66799510_66799957	0.17	PDE4B	phosphodiesterase 4B, cAMP-specific	1861	0.5
chr7_150416321_150416472	0.17	GIMAP1	GTPase, IMAP family member 1	2751	0.23
chr3_187726002_187726153	0.17	LPP	LIM domain containing preferred translocation partner in lipoma	144995	0.04
chr20_52226068_52226301	0.17	ZNF217	zinc finger protein 217	753	0.69
chr6_30648112_30648263	0.17	PPP1R18	protein phosphatase 1, regulatory subunit 18	6806	0.07
chr19_9902856_9903204	0.17	ZNF846	zinc finger protein 846	743	0.48
chr3_16342795_16343107	0.17	RP11-415F23.2		12995	0.16
chr2_169347644_169347797	0.17	CERS6	ceramide synthase 6	34961	0.16
chr1_198620819_198621442	0.17	PTPRC	protein tyrosine phosphatase, receptor type, C	12838	0.23
chr2_219082127_219082488	0.17	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	374	0.79
chr6_143256936_143257087	0.17	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	9327	0.26
chr9_37036362_37036543	0.17	PAX5	paired box 5	2349	0.32
chr1_116918127_116918427	0.17	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	1788	0.31
chr1_12675825_12676469	0.17	DHRS3	dehydrogenase/reductase (SDR family) member 3	1590	0.37
chr3_151911560_151911983	0.17	MBNL1	muscleblind-like splicing regulator 1	74058	0.11
chr18_18685478_18685632	0.17	ROCK1	Rho-associated, coiled-coil containing protein kinase 1	6257	0.22
chr1_154379631_154380335	0.17	RP11-350G8.5		943	0.42
chr15_45930000_45930287	0.16	SQRDL	sulfide quinone reductase-like (yeast)	3205	0.24
chr7_151572690_151573009	0.16	PRKAG2-AS1	PRKAG2 antisense RNA 1	1278	0.31
chr12_6445436_6445689	0.16	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	5452	0.13
chr16_2265337_2265543	0.16	PGP	phosphoglycolate phosphatase	632	0.39
chr1_198614847_198615101	0.16	PTPRC	protein tyrosine phosphatase, receptor type, C	6682	0.25
chr7_23338458_23338640	0.16	MALSU1	mitochondrial assembly of ribosomal large subunit 1	270	0.93
chr2_201989949_201990411	0.16	CFLAR	CASP8 and FADD-like apoptosis regulator	2980	0.18
chr8_27235851_27236002	0.16	PTK2B	protein tyrosine kinase 2 beta	2242	0.36
chr1_156784010_156784282	0.16	NTRK1	neurotrophic tyrosine kinase, receptor, type 1	1302	0.3
chr11_65409143_65409294	0.16	SIPA1	signal-induced proliferation-associated 1	919	0.33
chr22_31139652_31139831	0.16	ENSG00000264661	.	12197	0.17
chr2_162849236_162849504	0.16	ENSG00000253046	.	74078	0.1
chrY_14773573_14773724	0.16	USP9Y	ubiquitin specific peptidase 9, Y-linked	39512	0.22
chr7_129546585_129546878	0.16	UBE2H	ubiquitin-conjugating enzyme E2H	44436	0.1
chrX_129217430_129217581	0.16	ELF4	E74-like factor 4 (ets domain transcription factor)	26831	0.18
chr19_39825870_39826313	0.16	GMFG	glia maturation factor, gamma	554	0.58
chr7_143106132_143106395	0.16	EPHA1	EPH receptor A1	278	0.82
chr2_233926827_233927087	0.16	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	1768	0.35
chr19_4302092_4302295	0.16	TMIGD2	transmembrane and immunoglobulin domain containing 2	189	0.87
chr18_2641583_2641787	0.16	ENSG00000200875	.	8181	0.15
chr7_142334440_142334591	0.16	MTRNR2L6	MT-RNR2-like 6	39589	0.18
chr17_28706240_28706541	0.16	CPD	carboxypeptidase D	467	0.76
chrX_80353779_80353930	0.16	HMGN5	high mobility group nucleosome binding domain 5	23283	0.25
chr2_201676360_201676545	0.16	BZW1	basic leucine zipper and W2 domains 1	183	0.73
chr7_129420780_129420931	0.15	ENSG00000207691	.	6001	0.16
chr2_73181298_73181449	0.15	EMX1	empty spiracles homeobox 1	30256	0.19
chr16_79472215_79472382	0.15	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	161501	0.04
chr22_38791219_38791718	0.15	CSNK1E	casein kinase 1, epsilon	3059	0.17
chr16_30887671_30887822	0.15	MIR4519	microRNA 4519	513	0.52
chr1_198652510_198652661	0.15	RP11-553K8.5		16395	0.24
chr17_7239932_7240900	0.15	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	507	0.51
chr11_2198846_2198997	0.15	ENSG00000265258	.	4628	0.12
chr8_23075544_23076103	0.15	ENSG00000246582	.	6161	0.12
chrX_30473325_30473476	0.15	CXorf21	chromosome X open reading frame 21	122561	0.05
chr2_143889174_143889389	0.15	ARHGAP15	Rho GTPase activating protein 15	2398	0.38
chr19_4068105_4068310	0.15	ZBTB7A	zinc finger and BTB domain containing 7A	1264	0.32
chr16_85768387_85768538	0.15	ENSG00000222190	.	6844	0.12
chr15_34620156_34620427	0.15	SLC12A6	solute carrier family 12 (potassium/chloride transporter), member 6	8754	0.11
chr6_2900436_2900587	0.15	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	3003	0.24
chr6_32810383_32810534	0.15	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8	1339	0.24
chr12_21606326_21606605	0.15	PYROXD1	pyridine nucleotide-disulphide oxidoreductase domain 1	15616	0.17
chr17_56419518_56419935	0.15	BZRAP1-AS1	BZRAP1 antisense RNA 1	5007	0.12
chr16_68269729_68269880	0.15	ESRP2	epithelial splicing regulatory protein 2	231	0.8
chr1_206827719_206827870	0.15	DYRK3	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3	18620	0.12
chr12_55525482_55525633	0.15	OR9K2	olfactory receptor, family 9, subfamily K, member 2	2092	0.37
chr10_76345165_76345892	0.15	ENSG00000206756	.	34378	0.2
chr21_25801249_25801648	0.15	ENSG00000232512	.	671997	0.0
chr19_48759351_48759594	0.15	CARD8	caspase recruitment domain family, member 8	269	0.69
chr2_237446743_237446920	0.15	ACKR3	atypical chemokine receptor 3	29599	0.19
chr11_46848529_46848759	0.15	CKAP5	cytoskeleton associated protein 5	240	0.91
chrX_111922694_111923357	0.15	LHFPL1	lipoma HMGIC fusion partner-like 1	257	0.94
chr1_38471684_38471863	0.15	FHL3	four and a half LIM domains 3	596	0.64
chr17_5001058_5001209	0.15	ENSG00000234327	.	13630	0.09
chr5_146257138_146257401	0.15	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	936	0.67
chr10_90760175_90760505	0.15	ACTA2	actin, alpha 2, smooth muscle, aorta	9193	0.15
chr20_52225525_52225734	0.14	ZNF217	zinc finger protein 217	198	0.95
chr11_118036813_118036964	0.14	SCN2B	sodium channel, voltage-gated, type II, beta subunit	10500	0.14
chr4_54232426_54232649	0.14	SCFD2	sec1 family domain containing 2	295	0.92
chr11_2323518_2323777	0.14	TSPAN32	tetraspanin 32	267	0.57
chr4_90228457_90229530	0.14	GPRIN3	GPRIN family member 3	168	0.97
chr12_15107546_15107731	0.14	ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	3553	0.2
chr17_21155590_21155741	0.14	C17orf103	chromosome 17 open reading frame 103	913	0.52
chr11_63719409_63719560	0.14	NAA40	N(alpha)-acetyltransferase 40, NatD catalytic subunit	12764	0.1
chr19_48614158_48614373	0.14	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)	191	0.91
chr7_104908860_104909472	0.14	SRPK2	SRSF protein kinase 2	296	0.92
chr5_55775454_55775711	0.14	CTC-236F12.4	Uncharacterized protein	2014	0.36
chr16_11676228_11676379	0.14	LITAF	lipopolysaccharide-induced TNF factor	3926	0.23
chr18_56105832_56106078	0.14	ENSG00000207778	.	12351	0.17
chr6_130070208_130070770	0.14	ENSG00000211996	.	1607	0.48
chr1_226068766_226068917	0.14	TMEM63A	transmembrane protein 63A	1228	0.35
chr17_39741665_39741816	0.14	KRT14	keratin 14	1433	0.25
chr6_17704634_17704930	0.14	RP11-500C11.3		1706	0.27
chr15_91475141_91475394	0.14	HDDC3	HD domain containing 3	439	0.62
chr14_23013027_23013178	0.14	AE000662.92	Uncharacterized protein	12432	0.1
chr1_111745814_111746254	0.14	DENND2D	DENN/MADD domain containing 2D	997	0.41
chr18_11907803_11908245	0.14	MPPE1	metallophosphoesterase 1	248	0.78
chr22_30720802_30721186	0.14	TBC1D10A	TBC1 domain family, member 10A	1896	0.18
chr18_74836762_74837008	0.14	MBP	myelin basic protein	2783	0.4

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.3	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1	0.3	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1	0.2	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.2	GO:0021681	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.4	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.2	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.2	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.3	GO:0043368	positive T cell selection(GO:0043368)
0.0	0.1	GO:0010536	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0	0.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.2	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.0	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.2	GO:1904031	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.2	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.1	GO:0032367	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0	0.1	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.2	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.0	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0045329	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:1903514	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0071391	cellular response to estrogen stimulus(GO:0071391)
0.0	0.3	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.0	GO:0002713	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.0	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.0	GO:0045943	positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.0	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.0	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.2	GO:0046794	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.0	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.0	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0001787	natural killer cell proliferation(GO:0001787)
0.0	0.0	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0051310	metaphase plate congression(GO:0051310)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.0	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.0	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.0	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.1	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0	0.0	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.2	GO:0030101	natural killer cell activation(GO:0030101)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0072487	MSL complex(GO:0072487)
0.1	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	GO:0043218	compact myelin(GO:0043218)
0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	GO:0001652	granular component(GO:0001652)
0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0000145	exocyst(GO:0000145)
0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.1	GO:0070695	FHF complex(GO:0070695)
0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	GO:0031527	filopodium membrane(GO:0031527)
0.1	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.3	GO:0005839	proteasome core complex(GO:0005839)
0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	GO:0045120	pronucleus(GO:0045120)
0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.1	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.2	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.6	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.1	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.2	GO:0005522	profilin binding(GO:0005522)
0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.3	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	GO:0051734	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.1	GO:0045502	dynein binding(GO:0045502)
0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	GO:0003785	actin monomer binding(GO:0003785)
0.1	GO:0031013	troponin I binding(GO:0031013)
0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	GO:0017091	AU-rich element binding(GO:0017091)
0.0	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	GO:0034452	dynactin binding(GO:0034452)
0.2	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.1	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	GO:0003701	obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.1	GO:0036041	long-chain fatty acid binding(GO:0036041)
0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	GO:0050786	RAGE receptor binding(GO:0050786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.9	PID BCR 5PATHWAY	BCR signaling pathway
0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.4	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis