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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for GSC_GSC2

Z-value: 0.75

Motif logo

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Transcription factors associated with GSC_GSC2

Gene Symbol Gene ID Gene Info
GSC
ENSG00000133937.3 goosecoid homeobox
GSC2
ENSG00000063515.2 goosecoid homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_95363694_95363845GSC1272070.051511-0.853.8e-03Click!
chr14_95218837_95218988GSC176500.246162-0.599.4e-02Click!
chr14_95242002_95242153GSC55150.300144-0.521.6e-01Click!
chr14_95402811_95402962GSC1663240.032050-0.452.2e-01Click!
chr14_95236319_95236561GSC1220.9783580.412.8e-01Click!
chr22_19136719_19137042GSC29160.4143420.817.8e-03Click!
chr22_19137054_19137376GSC25810.6062630.684.4e-02Click!
chr22_19138892_19139181GSC212400.3101930.432.5e-01Click!

Activity of the GSC_GSC2 motif across conditions

Conditions sorted by the z-value of the GSC_GSC2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_128383033_128383215 0.46 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 7835
 0.24
chr4_109083741_109084005 0.40 LEF1
 lymphoid enhancer-binding factor 1
 3584
 0.27
chr17_73522364_73522644 0.39 LLGL2
 lethal giant larvae homolog 2 (Drosophila)
 634
 0.56
chr1_198610531_198610895 0.38 PTPRC
 protein tyrosine phosphatase, receptor type, C
 2421
 0.36
chr19_48752565_48752795 0.34 CARD8
 caspase recruitment domain family, member 8
 245
 0.88
chr16_27415626_27415898 0.34 IL21R
 interleukin 21 receptor
 1339
 0.47
chr12_122729504_122729668 0.33 VPS33A
 vacuolar protein sorting 33 homolog A (S. cerevisiae)
 5126
 0.17
chr12_47606378_47606570 0.32 PCED1B
 PC-esterase domain containing 1B
 3578
 0.27
chr20_43597121_43597440 0.31 STK4
 serine/threonine kinase 4
 2113
 0.25
chr1_226922484_226922931 0.31 ITPKB
 inositol-trisphosphate 3-kinase B
 2452
 0.34
chr11_66314663_66314814 0.30 ZDHHC24
 zinc finger, DHHC-type containing 24
 1029
 0.34
chr14_22952184_22952433 0.29 ENSG00000251002
 .
 360
 0.73
chr4_40200858_40201138 0.28 RHOH
 ras homolog family member H
 966
 0.6
chr2_113931904_113932161 0.28 PSD4
 pleckstrin and Sec7 domain containing 4
 458
 0.63
chr3_16329620_16329771 0.27 OXNAD1
 oxidoreductase NAD-binding domain containing 1
 18947
 0.15
chr12_51713121_51713481 0.27 BIN2
 bridging integrator 2
 4598
 0.18
chr2_192540821_192541028 0.27 NABP1
 nucleic acid binding protein 1
 1938
 0.47
chr12_109254375_109254526 0.27 DAO
 D-amino-acid oxidase
 1742
 0.29
chrX_21676275_21676631 0.26 KLHL34
 kelch-like family member 34
 5
 0.99
chr3_60066334_60066485 0.26 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 108826
 0.08
chrX_12991784_12992037 0.26 TMSB4X
 thymosin beta 4, X-linked
 1317
 0.51
chr19_6425433_6425584 0.26 KHSRP
 KH-type splicing regulatory protein
 703
 0.46
chr12_4381475_4382675 0.25 CCND2
 cyclin D2
 863
 0.52
chr1_25889390_25889576 0.25 LDLRAP1
 low density lipoprotein receptor adaptor protein 1
 19412
 0.19
chr4_3304601_3305007 0.25 RGS12
 regulator of G-protein signaling 12
 5958
 0.26
chr9_469822_470055 0.25 RP11-165F24.3
102
 0.79
chr5_134879321_134879990 0.24 NEUROG1
 neurogenin 1
 8016
 0.18
chr14_22466666_22466817 0.24 ENSG00000238634
 .
 144146
 0.04
chr12_103889282_103889433 0.24 C12orf42
 chromosome 12 open reading frame 42
 374
 0.91
chr3_63953694_63954206 0.24 ATXN7
 ataxin 7
 530
 0.74
chr13_41372571_41372761 0.24 SLC25A15
 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
 5372
 0.18
chr11_104904746_104905919 0.24 CASP1
 caspase 1, apoptosis-related cysteine peptidase
 508
 0.77
chr22_40304150_40304385 0.24 GRAP2
 GRB2-related adaptor protein 2
 7154
 0.18
chr14_100544647_100544798 0.23 CTD-2376I20.1
3507
 0.18
chrX_48771508_48771659 0.23 PIM2
 pim-2 oncogene
 1429
 0.23
chr13_68203141_68203292 0.23 PCDH9
 protocadherin 9
 398748
 0.01
chr15_40599321_40599893 0.23 PLCB2
 phospholipase C, beta 2
 419
 0.68
chr19_35630816_35630967 0.23 FXYD1
 FXYD domain containing ion transport regulator 1
 35
 0.95
chrX_11780001_11780185 0.23 MSL3
 male-specific lethal 3 homolog (Drosophila)
 2346
 0.44
chr6_32160504_32160787 0.23 GPSM3
 G-protein signaling modulator 3
 0
 0.94
chr20_34331618_34331769 0.23 RBM39
 RNA binding motif protein 39
 1459
 0.29
chr5_141062081_141062481 0.23 ARAP3
 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
 493
 0.75
chr2_175459196_175459684 0.22 WIPF1
 WAS/WASL interacting protein family, member 1
 3053
 0.24
chr1_117299964_117300188 0.22 CD2
 CD2 molecule
 2987
 0.29
chr14_22204676_22204903 0.22 ENSG00000222776
 .
 43996
 0.15
chr13_40532306_40532606 0.22 ENSG00000212553
 .
 101092
 0.08
chr3_112217855_112218341 0.22 BTLA
 B and T lymphocyte associated
 107
 0.98
chr6_128239129_128239316 0.22 THEMIS
 thymocyte selection associated
 463
 0.89
chr4_26886197_26886348 0.22 STIM2
 stromal interaction molecule 2
 23191
 0.22
chr17_38019635_38019786 0.22 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 669
 0.62
chr20_42360174_42360325 0.22 GTSF1L
 gametocyte specific factor 1-like
 4611
 0.26
chr2_198173822_198174153 0.22 ANKRD44
 ankyrin repeat domain 44
 1524
 0.32
chr4_81106153_81106599 0.21 PRDM8
 PR domain containing 8
 48
 0.98
chr15_80262648_80263745 0.21 BCL2A1
 BCL2-related protein A1
 315
 0.89
chr2_27487055_27487432 0.21 SLC30A3
 solute carrier family 30 (zinc transporter), member 3
 239
 0.85
chr16_3627461_3627612 0.21 NLRC3
 NLR family, CARD domain containing 3
 135
 0.95
chr5_159713959_159714110 0.21 ENSG00000243654
 .
 4761
 0.2
chr3_113250860_113251011 0.21 SIDT1
 SID1 transmembrane family, member 1
 208
 0.94
chr18_56326442_56326593 0.21 MALT1
 mucosa associated lymphoid tissue lymphoma translocation gene 1
 12101
 0.14
chr20_61438769_61438978 0.21 OGFR
 opioid growth factor receptor
 248
 0.85
chr10_70362033_70362257 0.21 TET1
 tet methylcytosine dioxygenase 1
 41732
 0.13
chr15_100890052_100890414 0.21 ADAMTS17
 ADAM metallopeptidase with thrombospondin type 1 motif, 17
 8023
 0.23
chr8_134509504_134509655 0.20 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 2025
 0.48
chr14_22203899_22204050 0.20 ENSG00000222776
 .
 44811
 0.15
chr16_67970526_67970748 0.20 PSMB10
 proteasome (prosome, macropain) subunit, beta type, 10
 353
 0.73
chr6_106969857_106970345 0.20 AIM1
 absent in melanoma 1
 10371
 0.2
chr19_53496276_53496464 0.20 ERVV-1
 endogenous retrovirus group V, member 1
 20804
 0.13
chr16_85769625_85769776 0.20 ENSG00000222190
 .
 5606
 0.13
chr10_14612285_14612533 0.20 FAM107B
 family with sequence similarity 107, member B
 1620
 0.47
chr14_22989269_22989534 0.20 TRAJ15
 T cell receptor alpha joining 15
 9179
 0.11
chr6_154568354_154568864 0.19 IPCEF1
 interaction protein for cytohesin exchange factors 1
 53
 0.99
chr14_22739869_22740020 0.19 ENSG00000238634
 .
 129057
 0.04
chr4_69433676_69433827 0.19 UGT2B17
 UDP glucuronosyltransferase 2 family, polypeptide B17
 494
 0.87
chr14_94543541_94543837 0.19 DDX24
 DEAD (Asp-Glu-Ala-Asp) box helicase 24
 3859
 0.17
chr14_61814123_61814302 0.19 PRKCH
 protein kinase C, eta
 397
 0.87
chr7_36327271_36327770 0.19 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 9233
 0.18
chr21_35306376_35306527 0.19 LINC00649
 long intergenic non-protein coding RNA 649
 2933
 0.21
chr5_40684385_40684698 0.19 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
 4941
 0.23
chr8_100714756_100715301 0.19 ENSG00000243254
 .
 88722
 0.08
chr4_149367147_149367363 0.19 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 1405
 0.59
chr1_25260510_25260661 0.19 RUNX3
 runt-related transcription factor 3
 4217
 0.26
chr1_66800579_66801197 0.19 PDE4B
 phosphodiesterase 4B, cAMP-specific
 3016
 0.39
chr4_40240088_40240239 0.18 RHOH
 ras homolog family member H
 38199
 0.16
chr10_120891057_120891670 0.18 FAM45A
 family with sequence similarity 45, member A
 27734
 0.11
chr6_37104092_37104243 0.18 PIM1
 pim-1 oncogene
 33812
 0.15
chr6_2902163_2902328 0.18 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
 1269
 0.44
chr3_72788121_72788360 0.18 ENSG00000222838
 .
 47278
 0.17
chr1_155146016_155146243 0.18 TRIM46
 tripartite motif containing 46
 225
 0.54
chr11_108099098_108099249 0.18 ENSG00000206967
 .
 1158
 0.42
chr8_65607910_65608061 0.18 RP11-1D12.1
39031
 0.2
chr2_238581678_238581829 0.18 LRRFIP1
 leucine rich repeat (in FLII) interacting protein 1
 19035
 0.2
chr1_202612976_202613127 0.18 SYT2
 synaptotagmin II
 470
 0.84
chr5_118623311_118623849 0.18 ENSG00000243333
 .
 18746
 0.17
chr13_99951513_99951834 0.18 GPR183
 G protein-coupled receptor 183
 7986
 0.2
chrX_44203680_44203969 0.18 EFHC2
 EF-hand domain (C-terminal) containing 2
 906
 0.71
chr11_133814931_133815363 0.18 IGSF9B
 immunoglobulin superfamily, member 9B
 1040
 0.55
chr6_139461625_139461834 0.18 HECA
 headcase homolog (Drosophila)
 5480
 0.28
chr7_38315629_38315780 0.18 STARD3NL
 STARD3 N-terminal like
 97707
 0.09
chr11_104787850_104788088 0.18 RP11-693N9.2
7327
 0.2
chr9_132402475_132402626 0.18 RP11-483H20.4
205
 0.89
chr1_154324818_154325020 0.18 ENSG00000238365
 .
 13700
 0.1
chr2_240188602_240189192 0.17 ENSG00000265215
 .
 38260
 0.14
chr22_51059908_51060313 0.17 ARSA
 arylsulfatase A
 6473
 0.1
chr11_128372497_128372648 0.17 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 2717
 0.34
chr14_23015065_23015417 0.17 AE000662.92
 Uncharacterized protein
 10293
 0.11
chr1_66799510_66799957 0.17 PDE4B
 phosphodiesterase 4B, cAMP-specific
 1861
 0.5
chr7_150416321_150416472 0.17 GIMAP1
 GTPase, IMAP family member 1
 2751
 0.23
chr3_187726002_187726153 0.17 LPP
 LIM domain containing preferred translocation partner in lipoma
 144995
 0.04
chr20_52226068_52226301 0.17 ZNF217
 zinc finger protein 217
 753
 0.69
chr6_30648112_30648263 0.17 PPP1R18
 protein phosphatase 1, regulatory subunit 18
 6806
 0.07
chr19_9902856_9903204 0.17 ZNF846
 zinc finger protein 846
 743
 0.48
chr3_16342795_16343107 0.17 RP11-415F23.2
12995
 0.16
chr2_169347644_169347797 0.17 CERS6
 ceramide synthase 6
 34961
 0.16
chr1_198620819_198621442 0.17 PTPRC
 protein tyrosine phosphatase, receptor type, C
 12838
 0.23
chr2_219082127_219082488 0.17 ARPC2
 actin related protein 2/3 complex, subunit 2, 34kDa
 374
 0.79
chr6_143256936_143257087 0.17 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 9327
 0.26
chr9_37036362_37036543 0.17 PAX5
 paired box 5
 2349
 0.32
chr1_116918127_116918427 0.17 ATP1A1
 ATPase, Na+/K+ transporting, alpha 1 polypeptide
 1788
 0.31
chr1_12675825_12676469 0.17 DHRS3
 dehydrogenase/reductase (SDR family) member 3
 1590
 0.37
chr3_151911560_151911983 0.17 MBNL1
 muscleblind-like splicing regulator 1
 74058
 0.11
chr18_18685478_18685632 0.17 ROCK1
 Rho-associated, coiled-coil containing protein kinase 1
 6257
 0.22
chr1_154379631_154380335 0.17 RP11-350G8.5
943
 0.42
chr15_45930000_45930287 0.16 SQRDL
 sulfide quinone reductase-like (yeast)
 3205
 0.24
chr7_151572690_151573009 0.16 PRKAG2-AS1
 PRKAG2 antisense RNA 1
 1278
 0.31
chr12_6445436_6445689 0.16 TNFRSF1A
 tumor necrosis factor receptor superfamily, member 1A
 5452
 0.13
chr16_2265337_2265543 0.16 PGP
 phosphoglycolate phosphatase
 632
 0.39
chr1_198614847_198615101 0.16 PTPRC
 protein tyrosine phosphatase, receptor type, C
 6682
 0.25
chr7_23338458_23338640 0.16 MALSU1
 mitochondrial assembly of ribosomal large subunit 1
 270
 0.93
chr2_201989949_201990411 0.16 CFLAR
 CASP8 and FADD-like apoptosis regulator
 2980
 0.18
chr8_27235851_27236002 0.16 PTK2B
 protein tyrosine kinase 2 beta
 2242
 0.36
chr1_156784010_156784282 0.16 NTRK1
 neurotrophic tyrosine kinase, receptor, type 1
 1302
 0.3
chr11_65409143_65409294 0.16 SIPA1
 signal-induced proliferation-associated 1
 919
 0.33
chr22_31139652_31139831 0.16 ENSG00000264661
 .
 12197
 0.17
chr2_162849236_162849504 0.16 ENSG00000253046
 .
 74078
 0.1
chrY_14773573_14773724 0.16 USP9Y
 ubiquitin specific peptidase 9, Y-linked
 39512
 0.22
chr7_129546585_129546878 0.16 UBE2H
 ubiquitin-conjugating enzyme E2H
 44436
 0.1
chrX_129217430_129217581 0.16 ELF4
 E74-like factor 4 (ets domain transcription factor)
 26831
 0.18
chr19_39825870_39826313 0.16 GMFG
 glia maturation factor, gamma
 554
 0.58
chr7_143106132_143106395 0.16 EPHA1
 EPH receptor A1
 278
 0.82
chr2_233926827_233927087 0.16 INPP5D
 inositol polyphosphate-5-phosphatase, 145kDa
 1768
 0.35
chr19_4302092_4302295 0.16 TMIGD2
 transmembrane and immunoglobulin domain containing 2
 189
 0.87
chr18_2641583_2641787 0.16 ENSG00000200875
 .
 8181
 0.15
chr7_142334440_142334591 0.16 MTRNR2L6
 MT-RNR2-like 6
 39589
 0.18
chr17_28706240_28706541 0.16 CPD
 carboxypeptidase D
 467
 0.76
chrX_80353779_80353930 0.16 HMGN5
 high mobility group nucleosome binding domain 5
 23283
 0.25
chr2_201676360_201676545 0.16 BZW1
 basic leucine zipper and W2 domains 1
 183
 0.73
chr7_129420780_129420931 0.15 ENSG00000207691
 .
 6001
 0.16
chr2_73181298_73181449 0.15 EMX1
 empty spiracles homeobox 1
 30256
 0.19
chr16_79472215_79472382 0.15 MAF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
 161501
 0.04
chr22_38791219_38791718 0.15 CSNK1E
 casein kinase 1, epsilon
 3059
 0.17
chr16_30887671_30887822 0.15 MIR4519
 microRNA 4519
 513
 0.52
chr1_198652510_198652661 0.15 RP11-553K8.5
16395
 0.24
chr17_7239932_7240900 0.15 ACAP1
 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
 507
 0.51
chr11_2198846_2198997 0.15 ENSG00000265258
 .
 4628
 0.12
chr8_23075544_23076103 0.15 ENSG00000246582
 .
 6161
 0.12
chrX_30473325_30473476 0.15 CXorf21
 chromosome X open reading frame 21
 122561
 0.05
chr2_143889174_143889389 0.15 ARHGAP15
 Rho GTPase activating protein 15
 2398
 0.38
chr19_4068105_4068310 0.15 ZBTB7A
 zinc finger and BTB domain containing 7A
 1264
 0.32
chr16_85768387_85768538 0.15 ENSG00000222190
 .
 6844
 0.12
chr15_34620156_34620427 0.15 SLC12A6
 solute carrier family 12 (potassium/chloride transporter), member 6
 8754
 0.11
chr6_2900436_2900587 0.15 SERPINB9
 serpin peptidase inhibitor, clade B (ovalbumin), member 9
 3003
 0.24
chr6_32810383_32810534 0.15 PSMB8
 proteasome (prosome, macropain) subunit, beta type, 8
 1339
 0.24
chr12_21606326_21606605 0.15 PYROXD1
 pyridine nucleotide-disulphide oxidoreductase domain 1
 15616
 0.17
chr17_56419518_56419935 0.15 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 5007
 0.12
chr16_68269729_68269880 0.15 ESRP2
 epithelial splicing regulatory protein 2
 231
 0.8
chr1_206827719_206827870 0.15 DYRK3
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
 18620
 0.12
chr12_55525482_55525633 0.15 OR9K2
 olfactory receptor, family 9, subfamily K, member 2
 2092
 0.37
chr10_76345165_76345892 0.15 ENSG00000206756
 .
 34378
 0.2
chr21_25801249_25801648 0.15 ENSG00000232512
 .
 671997
 0.0
chr19_48759351_48759594 0.15 CARD8
 caspase recruitment domain family, member 8
 269
 0.69
chr2_237446743_237446920 0.15 ACKR3
 atypical chemokine receptor 3
 29599
 0.19
chr11_46848529_46848759 0.15 CKAP5
 cytoskeleton associated protein 5
 240
 0.91
chrX_111922694_111923357 0.15 LHFPL1
 lipoma HMGIC fusion partner-like 1
 257
 0.94
chr1_38471684_38471863 0.15 FHL3
 four and a half LIM domains 3
 596
 0.64
chr17_5001058_5001209 0.15 ENSG00000234327
 .
 13630
 0.09
chr5_146257138_146257401 0.15 PPP2R2B
 protein phosphatase 2, regulatory subunit B, beta
 936
 0.67
chr10_90760175_90760505 0.15 ACTA2
 actin, alpha 2, smooth muscle, aorta
 9193
 0.15
chr20_52225525_52225734 0.14 ZNF217
 zinc finger protein 217
 198
 0.95
chr11_118036813_118036964 0.14 SCN2B
 sodium channel, voltage-gated, type II, beta subunit
 10500
 0.14
chr4_54232426_54232649 0.14 SCFD2
 sec1 family domain containing 2
 295
 0.92
chr11_2323518_2323777 0.14 TSPAN32
 tetraspanin 32
 267
 0.57
chr4_90228457_90229530 0.14 GPRIN3
 GPRIN family member 3
 168
 0.97
chr12_15107546_15107731 0.14 ARHGDIB
 Rho GDP dissociation inhibitor (GDI) beta
 3553
 0.2
chr17_21155590_21155741 0.14 C17orf103
 chromosome 17 open reading frame 103
 913
 0.52
chr11_63719409_63719560 0.14 NAA40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
 12764
 0.1
chr19_48614158_48614373 0.14 PLA2G4C
 phospholipase A2, group IVC (cytosolic, calcium-independent)
 191
 0.91
chr7_104908860_104909472 0.14 SRPK2
 SRSF protein kinase 2
 296
 0.92
chr5_55775454_55775711 0.14 CTC-236F12.4
 Uncharacterized protein
 2014
 0.36
chr16_11676228_11676379 0.14 LITAF
 lipopolysaccharide-induced TNF factor
 3926
 0.23
chr18_56105832_56106078 0.14 ENSG00000207778
 .
 12351
 0.17
chr6_130070208_130070770 0.14 ENSG00000211996
 .
 1607
 0.48
chr1_226068766_226068917 0.14 TMEM63A
 transmembrane protein 63A
 1228
 0.35
chr17_39741665_39741816 0.14 KRT14
 keratin 14
 1433
 0.25
chr6_17704634_17704930 0.14 RP11-500C11.3
1706
 0.27
chr15_91475141_91475394 0.14 HDDC3
 HD domain containing 3
 439
 0.62
chr14_23013027_23013178 0.14 AE000662.92
 Uncharacterized protein
 12432
 0.1
chr1_111745814_111746254 0.14 DENND2D
 DENN/MADD domain containing 2D
 997
 0.41
chr18_11907803_11908245 0.14 MPPE1
 metallophosphoesterase 1
 248
 0.78
chr22_30720802_30721186 0.14 TBC1D10A
 TBC1 domain family, member 10A
 1896
 0.18
chr18_74836762_74837008 0.14 MBP
 myelin basic protein
 2783
 0.4

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of GSC_GSC2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.3 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.1 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.2 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.2 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0043368 positive T cell selection(GO:0043368)
0.0 0.1 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.2 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0090085 regulation of protein deubiquitination(GO:0090085)
0.0 0.0 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:1903514 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0000154 rRNA modification(GO:0000154)
0.0 0.0 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0046794 multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.0 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.0 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.0 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:1903561 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.0 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.0 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.1 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.0 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.0 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis