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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for GZF1

Z-value: 0.78

Motif logo

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Transcription factors associated with GZF1

Gene Symbol Gene ID Gene Info
GZF1
ENSG00000125812.11 GDNF inducible zinc finger protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr20_23342076_23342460GZF15190.6436100.693.8e-02Click!
chr20_23346779_23346930GZF118330.210527-0.675.0e-02Click!
chr20_23343011_23343833GZF14650.6900430.324.0e-01Click!

Activity of the GZF1 motif across conditions

Conditions sorted by the z-value of the GZF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_118652704_118652966 0.44 ENO4
 enolase family member 4
 34290
 0.17
chr16_1257169_1257320 0.42 RP11-616M22.3
120
 0.92
chr16_375168_375449 0.41 AXIN1
 axin 1
 27141
 0.09
chr2_29537347_29537508 0.36 ALK
 anaplastic lymphoma receptor tyrosine kinase
 91167
 0.08
chr12_116985994_116986414 0.30 MAP1LC3B2
 microtubule-associated protein 1 light chain 3 beta 2
 10982
 0.28
chr20_42086642_42086854 0.30 SRSF6
 serine/arginine-rich splicing factor 6
 180
 0.93
chr10_104005591_104006435 0.29 GBF1
 golgi brefeldin A resistant guanine nucleotide exchange factor 1
 724
 0.58
chr10_14698721_14698872 0.29 RP11-7C6.1
4055
 0.23
chr7_64712185_64712407 0.29 ENSG00000265175
 .
 16013
 0.22
chr12_32115176_32115327 0.27 KIAA1551
 KIAA1551
 172
 0.96
chr6_157342303_157342500 0.27 RP1-137K2.2
98439
 0.08
chr8_142427875_142428034 0.27 PTP4A3
 protein tyrosine phosphatase type IVA, member 3
 4053
 0.16
chr8_21916945_21917106 0.26 DMTN
 dematin actin binding protein
 291
 0.84
chr11_96656080_96656231 0.25 ENSG00000200411
 .
 448299
 0.01
chr5_126323849_126324159 0.25 MARCH3
 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
 42496
 0.18
chr2_27603785_27604012 0.25 ZNF513
 zinc finger protein 513
 241
 0.83
chr12_53846681_53847472 0.25 PCBP2
 poly(rC) binding protein 2
 448
 0.72
chr5_132158669_132158820 0.24 SHROOM1
 shroom family member 1
 3088
 0.15
chr14_75894369_75894594 0.24 RP11-293M10.6
37
 0.52
chrX_75392544_75392813 0.24 PBDC1
 polysaccharide biosynthesis domain containing 1
 93
 0.98
chr9_133556690_133556909 0.23 EXOSC2
 exosome component 2
 12309
 0.18
chr12_11699256_11699407 0.22 ENSG00000251747
 .
 82
 0.97
chr14_21979649_21979818 0.22 METTL3
 methyltransferase like 3
 216
 0.9
chr14_52739518_52739669 0.22 PTGDR
 prostaglandin D2 receptor (DP)
 5063
 0.28
chr1_153643822_153644080 0.22 ILF2
 interleukin enhancer binding factor 2
 427
 0.65
chr14_106495447_106495598 0.22 IGHVIII-5-1
 immunoglobulin heavy variable (III)-5-1 (pseudogene)
 474
 0.43
chr20_34077433_34077600 0.22 RP3-477O4.14
1227
 0.32
chr19_49148382_49148554 0.21 CA11
 carbonic anhydrase XI
 1101
 0.28
chr9_139743848_139744034 0.21 PHPT1
 phosphohistidine phosphatase 1
 395
 0.63
chrX_129535378_129535825 0.20 RBMX2
 RNA binding motif protein, X-linked 2
 342
 0.89
chr1_27683876_27684079 0.20 MAP3K6
 mitogen-activated protein kinase kinase kinase 6
 1015
 0.4
chr19_3557088_3557331 0.20 MFSD12
 major facilitator superfamily domain containing 12
 192
 0.87
chr7_45019061_45019212 0.20 MYO1G
 myosin IG
 439
 0.76
chr21_15916676_15916915 0.20 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 1867
 0.42
chr3_45017798_45018180 0.20 EXOSC7
 exosome component 7
 267
 0.53
chr1_197170699_197171135 0.19 CRB1
 crumbs homolog 1 (Drosophila)
 325
 0.84
chr6_106545216_106545824 0.19 PRDM1
 PR domain containing 1, with ZNF domain
 961
 0.58
chr8_117885462_117886204 0.19 RAD21
 RAD21 homolog (S. pombe)
 766
 0.36
chr12_120662827_120663239 0.19 PXN
 paxillin
 480
 0.71
chr2_187351379_187351888 0.19 ZC3H15
 zinc finger CCCH-type containing 15
 653
 0.72
chr3_156393455_156393974 0.19 TIPARP
 TCDD-inducible poly(ADP-ribose) polymerase
 356
 0.85
chr12_3162069_3162220 0.19 TSPAN9
 tetraspanin 9
 24377
 0.17
chr1_199878058_199878346 0.18 ENSG00000200139
 .
 20915
 0.24
chr1_38260135_38260459 0.18 MANEAL
 mannosidase, endo-alpha-like
 142
 0.91
chr6_122792252_122792563 0.18 SERINC1
 serine incorporator 1
 560
 0.52
chr14_50319523_50319960 0.18 NEMF
 nuclear export mediator factor
 180
 0.85
chr8_6566608_6567048 0.18 AGPAT5
 1-acylglycerol-3-phosphate O-acyltransferase 5
 614
 0.61
chr5_67580975_67581126 0.18 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 3146
 0.37
chr3_52718835_52719171 0.18 PBRM1
 polybromo 1
 591
 0.42
chrX_106956955_106957175 0.18 TSC22D3
 TSC22 domain family, member 3
 2566
 0.34
chr6_89789489_89789998 0.18 RP11-63L7.5
643
 0.43
chr12_127630819_127631001 0.18 ENSG00000239776
 .
 19762
 0.3
chr2_28836714_28836865 0.18 PLB1
 phospholipase B1
 12003
 0.21
chr14_102227472_102227811 0.17 PPP2R5C
 protein phosphatase 2, regulatory subunit B', gamma
 494
 0.78
chr7_36305572_36305723 0.17 EEPD1
 endonuclease/exonuclease/phosphatase family domain containing 1
 31106
 0.15
chr8_21769341_21769492 0.17 DOK2
 docking protein 2, 56kDa
 1758
 0.36
chr11_36423391_36423542 0.17 PRR5L
 proline rich 5 like
 851
 0.61
chr22_30662105_30662275 0.17 OSM
 oncostatin M
 383
 0.75
chr12_104458290_104458598 0.16 HCFC2
 host cell factor C2
 148
 0.82
chr2_134877443_134877671 0.16 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 196
 0.96
chr8_29953492_29954050 0.16 LEPROTL1
 leptin receptor overlapping transcript-like 1
 606
 0.68
chr5_473388_473548 0.16 ENSG00000225138
 .
 117
 0.68
chr7_105362356_105362507 0.16 ATXN7L1
 ataxin 7-like 1
 30347
 0.23
chr6_34112105_34112270 0.16 GRM4
 glutamate receptor, metabotropic 4
 1670
 0.44
chr21_38073571_38073742 0.16 AP000697.6
208
 0.93
chr16_89557343_89557542 0.16 ANKRD11
 ankyrin repeat domain 11
 473
 0.69
chr3_158390470_158390795 0.16 LXN
 latexin
 150
 0.95
chr7_156803754_156804127 0.15 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 441
 0.56
chr1_92946934_92947085 0.15 GFI1
 growth factor independent 1 transcription repressor
 2502
 0.37
chr22_31619723_31619874 0.15 ENSG00000199695
 .
 959
 0.4
chrX_102631036_102631748 0.15 NGFRAP1
 nerve growth factor receptor (TNFRSF16) associated protein 1
 57
 0.97
chr10_103879598_103879834 0.15 LDB1
 LIM domain binding 1
 494
 0.73
chr3_81472677_81472828 0.15 ENSG00000222389
 .
 85875
 0.11
chr16_67876459_67876770 0.15 THAP11
 THAP domain containing 11
 401
 0.44
chr12_122326739_122327128 0.15 PSMD9
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
 241
 0.9
chr9_135117163_135117384 0.15 ENSG00000221105
 .
 27011
 0.2
chr5_170814799_170815118 0.15 NPM1
 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
 73
 0.95
chr17_73773061_73773428 0.15 H3F3B
 H3 histone, family 3B (H3.3B)
 2123
 0.16
chr19_58987134_58987390 0.14 CTD-2619J13.23
132
 0.64
chr12_125473806_125474002 0.14 DHX37
 DEAH (Asp-Glu-Ala-His) box polypeptide 37
 237
 0.93
chr20_61550921_61551072 0.14 DIDO1
 death inducer-obliterator 1
 5238
 0.16
chr6_167411127_167411495 0.14 ENSG00000265828
 .
 89
 0.93
chr16_68452108_68452259 0.14 SMPD3
 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
 30212
 0.12
chr1_239551018_239551169 0.14 CHRM3
 cholinergic receptor, muscarinic 3
 241280
 0.02
chr3_135969234_135969511 0.14 PCCB
 propionyl CoA carboxylase, beta polypeptide
 155
 0.97
chr15_31765016_31765167 0.14 KLF13
 Kruppel-like factor 13
 106734
 0.07
chr4_82135724_82136079 0.14 PRKG2
 protein kinase, cGMP-dependent, type II
 287
 0.94
chr13_53192037_53192369 0.14 HNRNPA1L2
 heterogeneous nuclear ribonucleoprotein A1-like 2
 598
 0.79
chr8_135844464_135844657 0.14 ENSG00000199153
 .
 27372
 0.21
chr21_36262594_36262745 0.14 RUNX1
 runt-related transcription factor 1
 582
 0.85
chr20_62612476_62612847 0.14 PRPF6
 pre-mRNA processing factor 6
 173
 0.87
chr9_74378842_74379095 0.14 TMEM2
 transmembrane protein 2
 4334
 0.34
chr6_57181574_57181908 0.13 PRIM2
 primase, DNA, polypeptide 2 (58kDa)
 681
 0.78
chr6_42418365_42418744 0.13 TRERF1
 transcriptional regulating factor 1
 445
 0.85
chr6_7108626_7109201 0.13 RREB1
 ras responsive element binding protein 1
 649
 0.77
chr9_95877171_95877322 0.13 C9orf89
 chromosome 9 open reading frame 89
 18746
 0.14
chr6_30524774_30525039 0.13 GNL1
 guanine nucleotide binding protein-like 1
 45
 0.63
chr5_133449213_133449364 0.13 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 1114
 0.56
chr14_36788990_36789756 0.13 MBIP
 MAP3K12 binding inhibitory protein 1
 297
 0.92
chr11_2502582_2502733 0.13 KCNQ1
 potassium voltage-gated channel, KQT-like subfamily, member 1
 19540
 0.16
chr12_90378520_90378671 0.13 ENSG00000252823
 .
 230759
 0.02
chr10_106083791_106084156 0.13 ITPRIP
 inositol 1,4,5-trisphosphate receptor interacting protein
 4709
 0.15
chr18_60988479_60988630 0.13 BCL2
 B-cell CLL/lymphoma 2
 1193
 0.44
chr13_73355012_73355163 0.13 DIS3
 DIS3 mitotic control homolog (S. cerevisiae)
 976
 0.39
chr9_80625845_80626079 0.13 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 19558
 0.28
chr21_42258267_42258418 0.13 DSCAM
 Down syndrome cell adhesion molecule
 39277
 0.21
chrX_153618503_153618757 0.13 RPL10
 ribosomal protein L10
 6865
 0.08
chrX_75365570_75365805 0.12 PBDC1
 polysaccharide biosynthesis domain containing 1
 27084
 0.25
chr6_109800480_109800632 0.12 ZBTB24
 zinc finger and BTB domain containing 24
 3884
 0.14
chr1_27951925_27952076 0.12 FGR
 feline Gardner-Rasheed sarcoma viral oncogene homolog
 646
 0.63
chr12_11803481_11804350 0.12 ETV6
 ets variant 6
 1127
 0.62
chr2_203775980_203776689 0.12 CARF
 calcium responsive transcription factor
 603
 0.45
chr2_220042618_220042887 0.12 CNPPD1
 cyclin Pas1/PHO80 domain containing 1
 76
 0.53
chr5_175962769_175963088 0.12 RNF44
 ring finger protein 44
 1493
 0.28
chr3_52007652_52007993 0.12 ABHD14A
 abhydrolase domain containing 14A
 122
 0.44
chr3_185654118_185654306 0.12 TRA2B
 transformer 2 beta homolog (Drosophila)
 1589
 0.4
chr4_155220038_155220189 0.12 ENSG00000264137
 .
 80052
 0.1
chr1_206135676_206135961 0.12 FAM72A
 family with sequence similarity 72, member A
 1419
 0.38
chr1_26758171_26758572 0.12 DHDDS
 dehydrodolichyl diphosphate synthase
 436
 0.76
chr8_146175786_146175956 0.12 ZNF16
 zinc finger protein 16
 110
 0.96
chr5_149521280_149521431 0.12 PDGFRB
 platelet-derived growth factor receptor, beta polypeptide
 4355
 0.17
chr10_104005118_104005269 0.12 GBF1
 golgi brefeldin A resistant guanine nucleotide exchange factor 1
 96
 0.95
chr17_56407127_56407278 0.12 BZRAP1-AS1
 BZRAP1 antisense RNA 1
 236
 0.8
chrX_153570073_153570387 0.12 XX-FW83128A1.2
6843
 0.1
chr2_27008209_27008614 0.12 CENPA
 centromere protein A
 454
 0.81
chr1_1004234_1004415 0.12 RNF223
 ring finger protein 223
 5363
 0.1
chr6_24774737_24775060 0.12 GMNN
 geminin, DNA replication inhibitor
 261
 0.9
chr12_9903163_9903484 0.12 CD69
 CD69 molecule
 10174
 0.15
chr17_62222536_62222687 0.12 ENSG00000199753
 .
 832
 0.44
chr9_108319921_108320392 0.12 RP11-235C23.5
154
 0.64
chr1_202310113_202310440 0.12 UBE2T
 ubiquitin-conjugating enzyme E2T (putative)
 832
 0.62
chr2_106777289_106777491 0.12 UXS1
 UDP-glucuronate decarboxylase 1
 309
 0.92
chr3_120068350_120069016 0.12 RP11-174O3.3
326
 0.63
chr14_70041081_70041336 0.12 CCDC177
 Homo sapiens coiled-coil domain containing 177 (CCDC177), mRNA.
 869
 0.67
chr20_10903511_10903679 0.12 RP11-103J8.1
20663
 0.27
chr11_36531965_36532300 0.12 TRAF6
 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
 310
 0.91
chr19_4633711_4633862 0.11 TNFAIP8L1
 tumor necrosis factor, alpha-induced protein 8-like 1
 5744
 0.13
chr11_118489320_118489642 0.11 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 11123
 0.11
chr22_32806330_32806481 0.11 RTCB
 RNA 2',3'-cyclic phosphate and 5'-OH ligase
 1819
 0.29
chr3_48693068_48693287 0.11 CELSR3
 cadherin, EGF LAG seven-pass G-type receptor 3
 7171
 0.09
chr13_46627012_46627449 0.11 CPB2-AS1
 CPB2 antisense RNA 1
 193
 0.67
chr12_8724646_8724797 0.11 ENSG00000238943
 .
 20351
 0.12
chr1_7765903_7766129 0.11 CAMTA1
 calmodulin binding transcription activator 1
 30452
 0.17
chr22_43355548_43355783 0.11 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 219
 0.95
chr12_102513335_102513786 0.11 NUP37
 nucleoporin 37kDa
 338
 0.53
chr1_149813796_149814193 0.11 HIST2H2AA3
 histone cluster 2, H2aa3
 484
 0.49
chr19_2237563_2237785 0.11 PLEKHJ1
 pleckstrin homology domain containing, family J member 1
 29
 0.59
chr7_72936777_72937003 0.11 BAZ1B
 bromodomain adjacent to zinc finger domain, 1B
 282
 0.88
chr20_5093003_5093662 0.11 TMEM230
 transmembrane protein 230
 67
 0.94
chr16_11763075_11763345 0.11 SNN
 stannin
 940
 0.56
chr5_162934649_162934884 0.11 MAT2B
 methionine adenosyltransferase II, beta
 2146
 0.28
chr5_55287822_55288099 0.11 IL6ST
 interleukin 6 signal transducer (gp130, oncostatin M receptor)
 2832
 0.2
chr2_30448704_30448864 0.11 LBH
 limb bud and heart development
 5613
 0.24
chr11_118868535_118868695 0.11 CCDC84
 coiled-coil domain containing 84
 237
 0.79
chr17_74137986_74138137 0.11 RNF157-AS1
 RNF157 antisense RNA 1
 464
 0.54
chr6_27841415_27841672 0.11 HIST1H4L
 histone cluster 1, H4l
 254
 0.76
chr14_50087068_50087296 0.11 RPL36AL
 ribosomal protein L36a-like
 221
 0.56
chr10_103576027_103576601 0.11 MGEA5
 meningioma expressed antigen 5 (hyaluronidase)
 1309
 0.34
chr8_144373646_144373987 0.11 ZNF696
 zinc finger protein 696
 224
 0.82
chr10_22541853_22542149 0.11 EBLN1
 endogenous Bornavirus-like nucleoprotein 1
 43051
 0.13
chrX_154445779_154445930 0.11 VBP1
 von Hippel-Lindau binding protein 1
 1211
 0.48
chr21_34864166_34864389 0.11 DNAJC28
 DnaJ (Hsp40) homolog, subfamily C, member 28
 250
 0.87
chr16_46723241_46723448 0.11 ORC6
 origin recognition complex, subunit 6
 214
 0.52
chr7_65762308_65762459 0.11 ENSG00000252126
 .
 46908
 0.14
chr16_22217946_22218447 0.11 EEF2K
 eukaryotic elongation factor-2 kinase
 593
 0.74
chr1_144593335_144593591 0.11 RP11-640M9.2
21668
 0.2
chr6_88412249_88412889 0.11 AKIRIN2
 akirin 2
 642
 0.73
chr6_11094046_11094248 0.10 SMIM13
 small integral membrane protein 13
 119
 0.96
chr5_168729442_168729593 0.10 SLIT3
 slit homolog 3 (Drosophila)
 1384
 0.54
chr17_18087734_18087959 0.10 RP11-258F1.1
135
 0.69
chrX_24072030_24072308 0.10 EIF2S3
 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
 664
 0.73
chr11_111957062_111957410 0.10 SDHD
 succinate dehydrogenase complex, subunit D, integral membrane protein
 261
 0.49
chr3_176915816_176916502 0.10 TBL1XR1
 transducin (beta)-like 1 X-linked receptor 1
 898
 0.7
chr9_131133752_131134483 0.10 URM1
 ubiquitin related modifier 1
 467
 0.68
chr2_43449640_43450246 0.10 ZFP36L2
 ZFP36 ring finger protein-like 2
 3805
 0.27
chr3_171176304_171176455 0.10 TNIK
 TRAF2 and NCK interacting kinase
 1473
 0.45
chrX_75368988_75369430 0.10 PBDC1
 polysaccharide biosynthesis domain containing 1
 23562
 0.26
chr1_192842951_192843102 0.10 ENSG00000223075
 .
 2089
 0.41
chr6_159072646_159072797 0.10 SYTL3
 synaptotagmin-like 3
 1675
 0.35
chr6_64345134_64345489 0.10 PHF3
 PHD finger protein 3
 414
 0.89
chr19_53104607_53104836 0.10 CTD-3099C6.11
2581
 0.16
chr12_14926776_14927159 0.10 H2AFJ
 H2A histone family, member J
 303
 0.82
chrX_9866552_9866703 0.10 SHROOM2
 shroom family member 2
 13785
 0.2
chr22_32057584_32058186 0.10 PISD
 phosphatidylserine decarboxylase
 281
 0.92
chr13_52767860_52768554 0.10 MRPS31P5
 mitochondrial ribosomal protein S31 pseudogene 5
 306
 0.91
chr5_35857770_35858187 0.10 IL7R
 interleukin 7 receptor
 984
 0.58
chr11_122050649_122050906 0.10 ENSG00000207994
 .
 27761
 0.16
chr11_62529664_62529976 0.10 POLR2G
 polymerase (RNA) II (DNA directed) polypeptide G
 783
 0.32
chr3_16351051_16351202 0.10 RP11-415F23.2
4820
 0.19
chr1_241840893_241841044 0.10 WDR64
 WD repeat domain 64
 5914
 0.23
chrX_124911556_124911707 0.10 ENSG00000222518
 .
 114732
 0.07
chr1_42181439_42181590 0.10 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 14842
 0.25
chr8_108509260_108510202 0.10 ANGPT1
 angiopoietin 1
 507
 0.89
chr22_51021623_51022044 0.10 CHKB-AS1
 CHKB antisense RNA 1 (head to head)
 378
 0.43
chr6_501893_502410 0.10 RP1-20B11.2
22020
 0.26
chrX_41280637_41281001 0.10 NYX
 nyctalopin
 25868
 0.18
chr6_47381977_47382964 0.10 ENSG00000266330
 .
 48182
 0.14
chr9_137217336_137217895 0.10 RXRA
 retinoid X receptor, alpha
 811
 0.72
chr9_136999905_137000059 0.10 WDR5
 WD repeat domain 5
 505
 0.59
chr4_123072364_123072515 0.10 KIAA1109
 KIAA1109
 1049
 0.65

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of GZF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.0 0.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 0.1 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.3 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.1 GO:0002540 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.0 0.2 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.0 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0021834 chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration(GO:0021834)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.2 GO:0001510 RNA methylation(GO:0001510)
0.0 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0002098 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0097205 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:0045006 DNA deamination(GO:0045006)
0.0 0.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.0 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0046885 regulation of hormone biosynthetic process(GO:0046885)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.0 GO:0042511 positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.0 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0045283 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 0.2 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.2 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.0 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.0 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.1 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.0 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA