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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HES1

Z-value: 0.69

Motif logo

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Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
HES1
ENSG00000114315.3 HES1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HES1chr3_193851589_19385186722060.2798220.618.1e-02Click!
HES1chr3_193855921_19385607220620.3129010.472.0e-01Click!
HES1chr3_193852202_19385281814240.403707-0.422.6e-01Click!
HES1chr3_193857154_19385735533200.2372610.393.0e-01Click!
HES1chr3_193857797_19385798539570.2204960.373.2e-01Click!

Activity of the HES1 motif across conditions

Conditions sorted by the z-value of the HES1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_112031428_112032221 0.92 AC004112.4
17854
 0.19
chr7_5466302_5466453 0.35 TNRC18
 trinucleotide repeat containing 18
 1332
 0.35
chr13_29068702_29069490 0.32 FLT1
 fms-related tyrosine kinase 1
 136
 0.98
chr9_132382165_132382732 0.31 C9orf50
 chromosome 9 open reading frame 50
 607
 0.62
chr1_66258526_66259233 0.30 PDE4B
 phosphodiesterase 4B, cAMP-specific
 15
 0.99
chr17_79318428_79319403 0.29 TMEM105
 transmembrane protein 105
 14441
 0.13
chr22_41633466_41634617 0.29 CHADL
 chondroadherin-like
 1584
 0.26
chr8_69242814_69243988 0.28 C8orf34
 chromosome 8 open reading frame 34
 56
 0.82
chr2_144694678_144695023 0.27 AC016910.1
210
 0.96
chr16_55542879_55544136 0.27 LPCAT2
 lysophosphatidylcholine acyltransferase 2
 597
 0.77
chr14_37667189_37667862 0.26 MIPOL1
 mirror-image polydactyly 1
 232
 0.92
chr7_5466974_5467725 0.25 TNRC18
 trinucleotide repeat containing 18
 2304
 0.22
chr7_15725092_15725754 0.25 MEOX2
 mesenchyme homeobox 2
 1014
 0.63
chrX_12156590_12157176 0.25 FRMPD4
 FERM and PDZ domain containing 4
 298
 0.9
chr3_181412989_181413321 0.25 SOX2-OT
 SOX2 overlapping transcript (non-protein coding)
 4126
 0.28
chr22_46659115_46659367 0.25 PKDREJ
 polycystin (PKD) family receptor for egg jelly
 22
 0.97
chr10_11784750_11785238 0.25 ECHDC3
 enoyl CoA hydratase domain containing 3
 549
 0.83
chr18_31020374_31020722 0.24 CCDC178
 coiled-coil domain containing 178
 109
 0.98
chr4_151500979_151501427 0.24 RP11-1336O20.2
962
 0.54
chr21_40032373_40032758 0.23 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 26
 0.99
chr1_14924992_14926197 0.23 KAZN
 kazrin, periplakin interacting protein
 381
 0.93
chr20_11871763_11872529 0.23 BTBD3
 BTB (POZ) domain containing 3
 171
 0.97
chr8_144512945_144513817 0.23 MAFA
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
 805
 0.48
chr3_8809480_8810320 0.23 OXTR
 oxytocin receptor
 463
 0.76
chr7_193046_193319 0.23 FAM20C
 family with sequence similarity 20, member C
 213
 0.89
chr3_196729783_196730213 0.23 MFI2-AS1
 MFI2 antisense RNA 1
 5
 0.97
chr14_89883615_89884477 0.22 FOXN3-AS1
 FOXN3 antisense RNA 1
 348
 0.65
chr3_98451018_98451517 0.22 ST3GAL6
 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
 27
 0.56
chr8_93114852_93115389 0.22 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 334
 0.94
chr17_79448132_79448599 0.22 RP11-1055B8.8
19402
 0.09
chr16_3095827_3096553 0.22 MMP25
 matrix metallopeptidase 25
 492
 0.51
chr5_63461313_63462499 0.22 RNF180
 ring finger protein 180
 83
 0.99
chr2_105458782_105459564 0.21 LINC01158
 long intergenic non-protein coding RNA 1158
 8738
 0.14
chr4_57975609_57976167 0.21 IGFBP7-AS1
 IGFBP7 antisense RNA 1
 40
 0.93
chr11_74442538_74442948 0.21 CHRDL2
 chordin-like 2
 313
 0.84
chr8_25042452_25043634 0.21 DOCK5
 dedicator of cytokinesis 5
 663
 0.75
chr10_126106510_126107495 0.21 OAT
 ornithine aminotransferase
 503
 0.8
chr20_11871067_11871503 0.21 BTBD3
 BTB (POZ) domain containing 3
 86
 0.98
chr8_38614830_38615236 0.21 TACC1
 transforming, acidic coiled-coil containing protein 1
 182
 0.95
chr2_68545863_68546629 0.20 CNRIP1
 cannabinoid receptor interacting protein 1
 286
 0.89
chr22_22011512_22012681 0.20 KB-1440D3.13
4127
 0.1
chr7_23513498_23513922 0.20 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 3624
 0.21
chr3_157260663_157261197 0.20 C3orf55
 chromosome 3 open reading frame 55
 105
 0.98
chrX_38079311_38080259 0.20 SRPX
 sushi-repeat containing protein, X-linked
 367
 0.75
chr7_143582018_143582424 0.20 FAM115A
 family with sequence similarity 115, member A
 242
 0.92
chr12_49627444_49627663 0.20 TUBA1C
 tubulin, alpha 1c
 5844
 0.13
chr5_131862398_131862590 0.20 IL5
 interleukin 5 (colony-stimulating factor, eosinophil)
 16720
 0.13
chr17_76164337_76165654 0.20 SYNGR2
 synaptogyrin 2
 244
 0.87
chr18_21851258_21851803 0.20 OSBPL1A
 oxysterol binding protein-like 1A
 666
 0.6
chr12_3308931_3310293 0.20 TSPAN9
 tetraspanin 9
 729
 0.75
chr3_192126971_192127690 0.20 FGF12
 fibroblast growth factor 12
 492
 0.87
chr17_59478776_59479020 0.20 RP11-332H18.5
1294
 0.27
chr9_132382776_132383013 0.20 C9orf50
 chromosome 9 open reading frame 50
 161
 0.92
chr2_121493751_121494304 0.20 GLI2
 GLI family zinc finger 2
 204
 0.97
chr1_205648469_205649627 0.19 SLC45A3
 solute carrier family 45, member 3
 539
 0.74
chr3_24562978_24563646 0.19 ENSG00000265028
 .
 386
 0.87
chr14_61104436_61104673 0.19 SIX1
 SIX homeobox 1
 11626
 0.21
chr20_6032553_6033205 0.19 LRRN4
 leucine rich repeat neuronal 4
 1816
 0.35
chr20_23617810_23618640 0.19 CST3
 cystatin C
 357
 0.87
chr9_94183938_94184089 0.19 NFIL3
 nuclear factor, interleukin 3 regulated
 2131
 0.44
chr9_139715640_139716017 0.19 RABL6
 RAB, member RAS oncogene family-like 6
 47
 0.93
chr2_242497891_242499073 0.19 BOK-AS1
 BOK antisense RNA 1
 90
 0.79
chr13_37005266_37006411 0.19 CCNA1
 cyclin A1
 129
 0.97
chr11_119019412_119020504 0.19 ABCG4
 ATP-binding cassette, sub-family G (WHITE), member 4
 5
 0.94
chr7_156400256_156401034 0.19 ENSG00000182648
 .
 2187
 0.32
chr11_62455448_62455813 0.19 LRRN4CL
 LRRN4 C-terminal like
 1741
 0.12
chr3_168864106_168864430 0.19 MECOM
 MDS1 and EVI1 complex locus
 59
 0.99
chr7_89949941_89950814 0.19 C7orf63
 chromosome 7 open reading frame 63
 13986
 0.16
chr20_49347136_49348386 0.18 PARD6B
 par-6 family cell polarity regulator beta
 320
 0.89
chr1_223743422_223744240 0.18 CAPN8
 calpain 8
 19451
 0.25
chr9_139742382_139743338 0.18 PHPT1
 phosphohistidine phosphatase 1
 316
 0.71
chr4_128543868_128544388 0.18 INTU
 inturned planar cell polarity protein
 298
 0.94
chr7_23511015_23511471 0.18 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 1157
 0.46
chr5_68788670_68789791 0.18 OCLN
 occludin
 612
 0.62
chr20_30457693_30458808 0.17 DUSP15
 dual specificity phosphatase 15
 125
 0.67
chr5_123987558_123987770 0.17 RP11-436H11.2
76860
 0.08
chr13_29106539_29107199 0.17 FLT1
 fms-related tyrosine kinase 1
 37604
 0.21
chr12_95043269_95044318 0.17 TMCC3
 transmembrane and coiled-coil domain family 3
 545
 0.85
chr17_79369714_79370212 0.17 RP11-1055B8.6
 Uncharacterized protein
 688
 0.54
chr6_46702576_46703631 0.17 PLA2G7
 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
 24
 0.97
chr16_54317621_54317889 0.17 IRX3
 iroquois homeobox 3
 2012
 0.4
chr21_46962488_46963290 0.17 SLC19A1
 solute carrier family 19 (folate transporter), member 1
 504
 0.83
chr3_127540841_127541975 0.17 MGLL
 monoglyceride lipase
 214
 0.96
chr1_21836241_21836468 0.17 ALPL
 alkaline phosphatase, liver/bone/kidney
 489
 0.83
chr5_76475983_76476746 0.17 PDE8B
 phosphodiesterase 8B
 29910
 0.15
chr19_13906290_13907522 0.16 ZSWIM4
 zinc finger, SWIM-type containing 4
 632
 0.39
chr15_66914300_66914605 0.16 RP11-321F6.1
 HCG2003567; Uncharacterized protein
 39924
 0.12
chr19_45655667_45657201 0.16 NKPD1
 NTPase, KAP family P-loop domain containing 1
 594
 0.58
chr9_127539201_127540134 0.16 OLFML2A
 olfactomedin-like 2A
 117
 0.95
chr8_49782515_49783288 0.16 SNAI2
 snail family zinc finger 2
 51087
 0.18
chr2_133061942_133062584 0.16 ENSG00000221288
 .
 47610
 0.14
chr17_78044749_78045392 0.16 CCDC40
 coiled-coil domain containing 40
 12346
 0.15
chr8_687260_687856 0.16 ERICH1-AS1
 ERICH1 antisense RNA 1
 93
 0.97
chr16_85783565_85784591 0.16 C16orf74
 chromosome 16 open reading frame 74
 479
 0.7
chr15_66994787_66995642 0.16 SMAD6
 SMAD family member 6
 540
 0.83
chr1_180881914_180882730 0.16 KIAA1614
 KIAA1614
 3
 0.98
chr6_35182117_35182910 0.16 SCUBE3
 signal peptide, CUB domain, EGF-like 3
 317
 0.9
chr1_215740105_215740888 0.16 KCTD3
 potassium channel tetramerization domain containing 3
 239
 0.96
chr9_86152792_86153773 0.16 FRMD3
 FERM domain containing 3
 71
 0.98
chr14_102094993_102095193 0.15 DIO3
 deiodinase, iodothyronine, type III
 67405
 0.09
chr4_682374_683342 0.15 MFSD7
 major facilitator superfamily domain containing 7
 74
 0.94
chr2_172944774_172945201 0.15 DLX1
 distal-less homeobox 1
 4481
 0.24
chr2_185463143_185463634 0.15 ZNF804A
 zinc finger protein 804A
 295
 0.95
chr10_44879737_44880262 0.15 CXCL12
 chemokine (C-X-C motif) ligand 12
 492
 0.84
chr7_38624277_38624485 0.15 AMPH
 amphiphysin
 46639
 0.16
chr6_19691587_19692480 0.15 ENSG00000200957
 .
 49273
 0.18
chrX_153199314_153200499 0.15 NAA10
 N(alpha)-acetyltransferase 10, NatA catalytic subunit
 505
 0.6
chr9_16063260_16063427 0.15 C9orf92
 chromosome 9 open reading frame 92
 152554
 0.04
chr20_32273512_32274295 0.15 E2F1
 E2F transcription factor 1
 307
 0.81
chr16_88450130_88450579 0.15 ZNF469
 zinc finger protein 469
 43525
 0.15
chr18_74322772_74323202 0.15 LINC00908
 long intergenic non-protein coding RNA 908
 82113
 0.09
chr1_110693132_110693795 0.15 SLC6A17
 solute carrier family 6 (neutral amino acid transporter), member 17
 355
 0.81
chrX_102318388_102319159 0.15 BEX1
 brain expressed, X-linked 1
 395
 0.83
chr2_172379612_172380165 0.15 CYBRD1
 cytochrome b reductase 1
 299
 0.93
chr16_57513132_57513388 0.15 DOK4
 docking protein 4
 457
 0.75
chr19_51871753_51871904 0.15 CLDND2
 claudin domain containing 2
 405
 0.61
chr6_105388737_105389249 0.15 LIN28B
 lin-28 homolog B (C. elegans)
 15930
 0.23
chr12_51236674_51236895 0.15 TMPRSS12
 transmembrane (C-terminal) protease, serine 12
 68
 0.95
chr4_6927779_6927930 0.14 TBC1D14
 TBC1 domain family, member 14
 15879
 0.16
chr1_162531480_162532245 0.14 UAP1
 UDP-N-acteylglucosamine pyrophosphorylase 1
 539
 0.55
chr2_69968563_69969704 0.14 ANXA4
 annexin A4
 27
 0.98
chr8_116675050_116675578 0.14 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr10_19777990_19778239 0.14 MALRD1
 MAM and LDL receptor class A domain containing 1
 91
 0.98
chr9_115774055_115774548 0.14 ZFP37
 ZFP37 zinc finger protein
 44667
 0.16
chrX_53349448_53350467 0.14 IQSEC2
 IQ motif and Sec7 domain 2
 565
 0.73
chr10_71812550_71812868 0.14 H2AFY2
 H2A histone family, member Y2
 73
 0.98
chr15_47476270_47477144 0.14 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 409
 0.87
chr1_240161229_240161618 0.14 FMN2
 formin 2
 16225
 0.27
chr17_31255277_31255844 0.14 TMEM98
 transmembrane protein 98
 332
 0.89
chr3_196415381_196415617 0.14 ENSG00000201441
 .
 20336
 0.11
chr3_158449888_158450546 0.14 RARRES1
 retinoic acid receptor responder (tazarotene induced) 1
 14
 0.36
chr11_89520365_89520516 0.14 TRIM64DP
 tripartite motif containing 64D, pseudogene
 10291
 0.21
chr11_109964287_109965206 0.14 ZC3H12C
 zinc finger CCCH-type containing 12C
 659
 0.83
chr2_236403404_236403896 0.14 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 899
 0.65
chr10_77168132_77169350 0.14 ENSG00000237149
 .
 5929
 0.2
chr9_88713671_88714373 0.14 GOLM1
 golgi membrane protein 1
 451
 0.9
chr5_153990189_153990659 0.14 ENSG00000264760
 .
 14792
 0.21
chr10_101088892_101089952 0.14 CNNM1
 cyclin M1
 266
 0.95
chr7_127672748_127672947 0.14 LRRC4
 leucine rich repeat containing 4
 687
 0.76
chr11_69453965_69454310 0.14 CCND1
 cyclin D1
 1718
 0.41
chr12_14720104_14720509 0.14 RP11-695J4.2
378
 0.73
chr9_138943188_138943742 0.14 NACC2
 NACC family member 2, BEN and BTB (POZ) domain containing
 1039
 0.58
chr5_149864820_149865733 0.14 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 105
 0.97
chr9_33523659_33524999 0.14 ANKRD18B
 ankyrin repeat domain 18B
 63
 0.97
chr4_119273101_119273655 0.14 PRSS12
 protease, serine, 12 (neurotrypsin, motopsin)
 780
 0.76
chr15_96888963_96889465 0.14 ENSG00000222651
 .
 12724
 0.15
chr9_25678314_25678778 0.14 TUSC1
 tumor suppressor candidate 1
 310
 0.95
chr9_112083182_112083638 0.13 EPB41L4B
 erythrocyte membrane protein band 4.1 like 4B
 166
 0.95
chr5_2756564_2757124 0.13 C5orf38
 chromosome 5 open reading frame 38
 4465
 0.28
chr2_79739509_79740065 0.13 CTNNA2
 catenin (cadherin-associated protein), alpha 2
 339
 0.91
chr20_9048816_9049419 0.13 PLCB4
 phospholipase C, beta 4
 293
 0.9
chr2_121499238_121499672 0.13 GLI2
 GLI family zinc finger 2
 5632
 0.32
chr9_133813639_133813991 0.13 FIBCD1
 fibrinogen C domain containing 1
 422
 0.82
chr17_72839202_72839484 0.13 GRIN2C
 glutamate receptor, ionotropic, N-methyl D-aspartate 2C
 16655
 0.11
chr5_38846105_38846894 0.13 OSMR
 oncostatin M receptor
 398
 0.91
chr19_45350061_45350833 0.13 PVRL2
 poliovirus receptor-related 2 (herpesvirus entry mediator B)
 664
 0.57
chr18_77547944_77548277 0.13 KCNG2
 potassium voltage-gated channel, subfamily G, member 2
 75558
 0.1
chr1_159750747_159751482 0.13 DUSP23
 dual specificity phosphatase 23
 321
 0.85
chr3_39093427_39094272 0.13 WDR48
 WD repeat domain 48
 57
 0.97
chr12_124155530_124156430 0.13 TCTN2
 tectonic family member 2
 320
 0.85
chr1_119530163_119530409 0.13 TBX15
 T-box 15
 142
 0.97
chr11_86382517_86383664 0.13 ME3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 150
 0.98
chr9_110250307_110251795 0.13 KLF4
 Kruppel-like factor 4 (gut)
 360
 0.89
chr13_52979416_52980324 0.13 THSD1
 thrombospondin, type I, domain containing 1
 393
 0.85
chrX_19140154_19140583 0.13 GPR64
 G protein-coupled receptor 64
 211
 0.97
chr7_131240036_131240570 0.13 PODXL
 podocalyxin-like
 1063
 0.65
chr10_79396627_79397649 0.13 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 67
 0.98
chr5_131745958_131747299 0.13 C5orf56
 chromosome 5 open reading frame 56
 45
 0.96
chr17_1936770_1936951 0.13 DPH1
 diphthamide biosynthesis 1
 173
 0.88
chr11_128494350_128494501 0.13 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 36972
 0.16
chr5_176921947_176922464 0.13 RP11-1334A24.6
209
 0.86
chrX_37208613_37209248 0.13 PRRG1
 proline rich Gla (G-carboxyglutamic acid) 1
 298
 0.54
chr22_41843038_41844299 0.13 TOB2
 transducer of ERBB2, 2
 641
 0.64
chr8_56851767_56852412 0.13 LYN
 v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
 704
 0.63
chr18_74843262_74844680 0.13 MBP
 myelin basic protein
 331
 0.94
chr7_45002030_45002849 0.13 RP4-647J21.1
1931
 0.25
chr1_1207989_1209115 0.13 UBE2J2
 ubiquitin-conjugating enzyme E2, J2
 299
 0.76
chr5_136834312_136835008 0.13 SPOCK1
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
 328
 0.92
chr6_5084934_5086227 0.13 PPP1R3G
 protein phosphatase 1, regulatory subunit 3G
 140
 0.97
chr3_147128128_147129466 0.13 ZIC1
 Zic family member 1
 1626
 0.36
chr1_30603166_30603378 0.13 ENSG00000222787
 .
 245523
 0.02
chr11_61595087_61595308 0.13 FADS2
 fatty acid desaturase 2
 36
 0.95
chr13_96204772_96205414 0.13 CLDN10
 claudin 10
 114
 0.97
chr22_50781024_50781650 0.12 PPP6R2
 protein phosphatase 6, regulatory subunit 2
 396
 0.74
chr19_49617571_49617790 0.12 LIN7B
 lin-7 homolog B (C. elegans)
 1
 0.94
chr10_49514049_49514506 0.12 MAPK8
 mitogen-activated protein kinase 8
 421
 0.88
chr19_21769065_21769964 0.12 RP11-678G14.2
17475
 0.22
chr21_40984409_40984913 0.12 C21orf88
 chromosome 21 open reading frame 88
 87
 0.97
chr3_49055259_49056395 0.12 DALRD3
 DALR anticodon binding domain containing 3
 170
 0.84
chr18_2906194_2907483 0.12 RP11-737O24.5
14126
 0.16
chr2_177502027_177502943 0.12 ENSG00000252027
 .
 26919
 0.25
chr3_120004025_120004467 0.12 GPR156
 G protein-coupled receptor 156
 305
 0.92
chr19_33790953_33791293 0.12 CTD-2540B15.11
283
 0.79
chr8_99439239_99439631 0.12 KCNS2
 potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
 185
 0.95
chr5_132158871_132159069 0.12 SHROOM1
 shroom family member 1
 2862
 0.16
chr1_115397478_115398199 0.12 SYCP1
 synaptonemal complex protein 1
 84
 0.98
chr5_114193628_114194015 0.12 RP11-492A10.1
189714
 0.03
chr7_5467738_5468320 0.12 TNRC18
 trinucleotide repeat containing 18
 2984
 0.19
chr19_45147190_45148055 0.12 PVR
 poliovirus receptor
 225
 0.9
chr2_236578912_236579455 0.12 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 935
 0.7

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HES1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.3 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.3 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.2 GO:0060453 regulation of gastric acid secretion(GO:0060453)
0.1 0.1 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.1 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.2 GO:0032328 alanine transport(GO:0032328)
0.1 0.1 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.1 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0044321 cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0021932 hindbrain radial glia guided cell migration(GO:0021932)
0.0 0.3 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.2 GO:0048343 paraxial mesodermal cell differentiation(GO:0048342) paraxial mesodermal cell fate commitment(GO:0048343)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.7 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.0 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0060510 lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.2 GO:0090026 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0060872 semicircular canal development(GO:0060872)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.2 GO:0015884 folic acid transport(GO:0015884)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0071875 adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0010658 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.1 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0033630 positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.1 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.0 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.0 GO:0072193 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0043096 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.0 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0042663 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.2 GO:0030539 male genitalia development(GO:0030539)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.0 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.0 GO:0003309 type B pancreatic cell differentiation(GO:0003309)
0.0 0.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0006837 serotonin transport(GO:0006837)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0010454 negative regulation of cell fate commitment(GO:0010454)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0045987 positive regulation of smooth muscle contraction(GO:0045987)
0.0 0.0 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.0 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.0 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.0 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0005771 multivesicular body(GO:0005771)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.0 GO:0044462 external encapsulating structure part(GO:0044462)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.2 GO:0008518 reduced folate carrier activity(GO:0008518)
0.1 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.3 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0002060 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0 0.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0004954 prostanoid receptor activity(GO:0004954)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0001077 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.0 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.0 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions