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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HESX1

Z-value: 1.66

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Transcription factors associated with HESX1

Gene Symbol	Gene ID	Gene Info
HESX1 Ensembl NCBI GeneCards UniProt	ENSG00000163666.4	HESX homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr3_57230756_57231045	HESX1	3066	0.241173	0.67	5.0e-02	Click!
chr3_57231282_57231557	HESX1	2547	0.266857	0.64	6.1e-02	Click!
chr3_57231564_57231715	HESX1	2327	0.282316	0.44	2.3e-01	Click!
chr3_57230583_57230734	HESX1	3308	0.232692	0.44	2.4e-01	Click!
chr3_57260241_57260521	HESX1	168	0.927401	-0.13	7.4e-01	Click!

Activity of the HESX1 motif across conditions

Conditions sorted by the z-value of the HESX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_16869822_16870309	0.64	BNC2	basonuclin 2	639	0.83
chr20_50384318_50384901	0.62	ATP9A	ATPase, class II, type 9A	258	0.94
chr4_57975609_57976167	0.61	IGFBP7-AS1	IGFBP7 antisense RNA 1	40	0.93
chr10_20106092_20106642	0.52	PLXDC2	plexin domain containing 2	1199	0.49
chr20_31062740_31063476	0.51	C20orf112	chromosome 20 open reading frame 112	8166	0.18
chr8_23711375_23711668	0.51	STC1	stanniocalcin 1	303	0.92
chrX_105969921_105970262	0.47	RNF128	ring finger protein 128, E3 ubiquitin protein ligase	197	0.96
chr9_16726683_16727481	0.46	RP11-62F24.2		270	0.85
chr10_35102956_35103650	0.46	PARD3	par-3 family cell polarity regulator	946	0.5
chr5_9544908_9545592	0.46	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	937	0.56
chr11_126870507_126870686	0.46	KIRREL3	kin of IRRE like 3 (Drosophila)	59	0.96
chr8_116463616_116464117	0.45	TRPS1	trichorhinophalangeal syndrome I	40582	0.2
chr10_122216781_122217284	0.45	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A	273	0.93
chr1_120173925_120174356	0.44	ZNF697	zinc finger protein 697	16256	0.17
chr3_25470006_25470271	0.44	RARB	retinoic acid receptor, beta	336	0.93
chr17_81041156_81041564	0.44	METRNL	meteorin, glial cell differentiation regulator-like	589	0.79
chr10_21798969_21799358	0.43	SKIDA1	SKI/DACH domain containing 1	7685	0.13
chr13_38443188_38443573	0.43	TRPC4	transient receptor potential cation channel, subfamily C, member 4	480	0.86
chr11_16023597_16024065	0.42	CTD-3096P4.1		20905	0.28
chr1_94703270_94703530	0.42	ARHGAP29	Rho GTPase activating protein 29	211	0.96
chr12_46760644_46760919	0.40	SLC38A2	solute carrier family 38, member 2	1691	0.42
chr21_31311288_31312406	0.40	GRIK1	glutamate receptor, ionotropic, kainate 1	3	0.99
chr19_17889339_17889635	0.39	FCHO1	FCH domain only 1	15975	0.11
chr10_20105417_20106037	0.39	PLXDC2	plexin domain containing 2	559	0.77
chr4_134069309_134069654	0.39	PCDH10	protocadherin 10	989	0.73
chr16_55542879_55544136	0.39	LPCAT2	lysophosphatidylcholine acyltransferase 2	597	0.77
chr10_49812568_49813319	0.38	ARHGAP22	Rho GTPase activating protein 22	54	0.98
chrX_132548696_132549413	0.38	GPC4	glypican 4	464	0.88
chr1_66258526_66259233	0.38	PDE4B	phosphodiesterase 4B, cAMP-specific	15	0.99
chr17_27045033_27045379	0.37	RAB34	RAB34, member RAS oncogene family	5	0.89
chr3_131854540_131854927	0.36	CPNE4	copine IV	96283	0.08
chr6_128828944_128829440	0.36	RP1-86D1.4		2922	0.22
chr4_157892760_157892940	0.36	PDGFC	platelet derived growth factor C	304	0.92
chr1_178063691_178064117	0.35	RASAL2	RAS protein activator like 2	628	0.84
chr5_71403752_71403990	0.35	MAP1B	microtubule-associated protein 1B	558	0.84
chr16_73081294_73081963	0.35	ZFHX3	zinc finger homeobox 3	646	0.76
chr20_23617810_23618640	0.35	CST3	cystatin C	357	0.87
chr4_141677411_141678112	0.35	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)	487	0.81
chr2_85981284_85981596	0.35	ATOH8	atonal homolog 8 (Drosophila)	423	0.8
chr19_1154555_1155129	0.35	SBNO2	strawberry notch homolog 2 (Drosophila)	293	0.85
chr21_33893367_33893849	0.35	ENSG00000252045	.	17001	0.16
chr12_105476938_105477089	0.35	ALDH1L2	aldehyde dehydrogenase 1 family, member L2	1328	0.39
chr7_27138540_27138742	0.34	HOTAIRM1	HOXA transcript antisense RNA, myeloid-specific 1	183	0.86
chr6_125684588_125685144	0.34	RP11-735G4.1		10604	0.27
chr5_151065179_151065606	0.34	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	601	0.67
chr5_127874204_127874722	0.34	FBN2	fibrillin 2	547	0.58
chr12_54367124_54367311	0.34	HOXC11	homeobox C11	305	0.69
chr5_172754207_172754714	0.34	STC2	stanniocalcin 2	596	0.75
chr4_187647302_187647732	0.33	FAT1	FAT atypical cadherin 1	359	0.93
chr5_131594297_131594770	0.33	PDLIM4	PDZ and LIM domain 4	1133	0.45
chr1_45140674_45140825	0.33	C1orf228	chromosome 1 open reading frame 228	322	0.62
chr16_401820_402085	0.33	AXIN1	axin 1	497	0.67
chr16_70780347_70780498	0.33	RP11-394B2.6		538	0.68
chr5_54516767_54517029	0.33	MCIDAS	multiciliate differentiation and DNA synthesis associated cell cycle protein	6245	0.13
chr8_77586350_77586717	0.33	ZFHX4	zinc finger homeobox 4	6921	0.24
chr11_15135960_15136328	0.33	INSC	inscuteable homolog (Drosophila)	340	0.92
chr7_12811096_12811403	0.33	ENSG00000199470	.	70735	0.11
chr7_116312458_116312799	0.33	MET	met proto-oncogene	169	0.97
chr10_93389674_93389884	0.33	PPP1R3C	protein phosphatase 1, regulatory subunit 3C	3032	0.38
chr2_62638898_62639095	0.33	ENSG00000241625	.	79317	0.09
chr2_227660848_227660999	0.33	IRS1	insulin receptor substrate 1	3552	0.25
chr11_63774609_63774760	0.33	OTUB1	OTU domain, ubiquitin aldehyde binding 1	20370	0.1
chr22_46482353_46482522	0.32	FLJ27365	hsa-mir-4763	554	0.6
chr6_146755730_146756219	0.32	ENSG00000222971	.	94418	0.08
chr6_121762848_121763040	0.32	GJA1	gap junction protein, alpha 1, 43kDa	6106	0.19
chr1_78956350_78956733	0.32	PTGFR	prostaglandin F receptor (FP)	216	0.96
chr1_214723918_214724069	0.32	PTPN14	protein tyrosine phosphatase, non-receptor type 14	573	0.84
chr13_93880393_93880808	0.32	GPC6	glypican 6	1505	0.58
chr22_46402821_46403014	0.32	WNT7B	wingless-type MMTV integration site family, member 7B	29908	0.1
chr9_126088906_126089175	0.31	CRB2	crumbs homolog 2 (Drosophila)	29409	0.19
chr12_6493326_6493955	0.31	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	221	0.89
chr9_129884150_129884930	0.31	ANGPTL2	angiopoietin-like 2	373	0.9
chr19_7953457_7953661	0.31	LRRC8E	leucine rich repeat containing 8 family, member E	123	0.88
chr1_32169073_32169273	0.31	COL16A1	collagen, type XVI, alpha 1	595	0.68
chr15_54270683_54271135	0.31	UNC13C	unc-13 homolog C (C. elegans)	34192	0.24
chr1_1293449_1293856	0.31	MXRA8	matrix-remodelling associated 8	263	0.78
chr2_9347772_9348251	0.31	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	1117	0.65
chr1_221067632_221067991	0.31	HLX	H2.0-like homeobox	13227	0.2
chr1_82267993_82268232	0.31	LPHN2	latrophilin 2	2030	0.49
chr21_30674225_30674446	0.30	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	1212	0.49
chr15_63768789_63769109	0.30	USP3	ubiquitin specific peptidase 3	27844	0.2
chr20_10651904_10652220	0.30	RP11-103J8.1		1514	0.43
chr12_30949792_30950072	0.30	CAPRIN2	caprin family member 2	42047	0.19
chr17_15168005_15168252	0.30	PMP22	peripheral myelin protein 22	496	0.74
chr5_76254834_76254985	0.30	CRHBP	corticotropin releasing hormone binding protein	6035	0.19
chr9_130860823_130861938	0.29	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	544	0.57
chr11_109293842_109294216	0.29	C11orf87	chromosome 11 open reading frame 87	1183	0.65
chr7_27201576_27201920	0.29	HOXA9	homeobox A9	3397	0.07
chr11_111848035_111848630	0.29	DIXDC1	DIX domain containing 1	299	0.84
chr5_171380881_171381289	0.29	FBXW11	F-box and WD repeat domain containing 11	23675	0.23
chr5_169398359_169398694	0.29	FAM196B	family with sequence similarity 196, member B	9218	0.26
chr4_89978098_89978439	0.29	FAM13A	family with sequence similarity 13, member A	43	0.98
chr4_74809740_74810515	0.29	PF4	platelet factor 4	37714	0.11
chr11_65203008_65203266	0.29	ENSG00000245532	.	8792	0.12
chr3_16006218_16006514	0.28	ENSG00000207815	.	91088	0.08
chr17_13504273_13504480	0.28	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	868	0.71
chr13_38445031_38445182	0.28	TRPC4	transient receptor potential cation channel, subfamily C, member 4	544	0.83
chr3_15837342_15837579	0.28	ANKRD28	ankyrin repeat domain 28	568	0.79
chr6_72178498_72178870	0.28	ENSG00000207827	.	65360	0.11
chr18_12253921_12254616	0.28	CIDEA	cell death-inducing DFFA-like effector a	50	0.98
chr14_89021348_89021679	0.28	PTPN21	protein tyrosine phosphatase, non-receptor type 21	436	0.78
chr11_57528799_57529076	0.28	CTNND1	catenin (cadherin-associated protein), delta 1	297	0.86
chr11_47663191_47664130	0.28	MTCH2	mitochondrial carrier 2	426	0.74
chr20_19956550_19956867	0.28	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	41052	0.15
chr19_7735107_7735328	0.28	RETN	resistin	1004	0.3
chr16_29126642_29126901	0.27	CTB-134H23.3		8005	0.16
chr20_9048816_9049419	0.27	PLCB4	phospholipase C, beta 4	293	0.9
chr2_176932269_176932561	0.27	EVX2	even-skipped homeobox 2	16226	0.1
chr10_101756725_101756967	0.27	DNMBP	dynamin binding protein	12830	0.18
chr6_169653019_169653284	0.27	THBS2	thrombospondin 2	905	0.7
chr22_50913109_50913431	0.27	SBF1	SET binding factor 1	101	0.92
chr8_25042452_25043634	0.27	DOCK5	dedicator of cytokinesis 5	663	0.75
chr15_41913046_41914152	0.27	MGA	MGA, MAX dimerization protein	135	0.96
chr7_27204317_27204592	0.27	HOXA9	homeobox A9	691	0.36
chr9_38068307_38068649	0.27	SHB	Src homology 2 domain containing adaptor protein B	730	0.76
chr1_150602792_150602943	0.26	ENSA	endosulfine alpha	795	0.5
chr6_138910192_138910343	0.26	NHSL1	NHS-like 1	16590	0.25
chr6_139691315_139691533	0.26	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	3926	0.31
chr17_2658644_2658831	0.26	ENSG00000265566	.	1611	0.28
chr22_36862847_36862998	0.26	TXN2	thioredoxin 2	14465	0.14
chr16_14280583_14281066	0.26	MKL2	MKL/myocardin-like 2	52	0.98
chr17_79369714_79370212	0.26	RP11-1055B8.6	Uncharacterized protein	688	0.54
chr12_3034547_3034860	0.26	ENSG00000238689	.	3428	0.16
chr5_31274350_31274565	0.26	RP11-152K4.2		6740	0.3
chr11_79685002_79685197	0.26	ENSG00000221551	.	281676	0.01
chr6_84743877_84744134	0.26	MRAP2	melanocortin 2 receptor accessory protein 2	530	0.87
chr3_150088154_150088521	0.26	TSC22D2	TSC22 domain family, member 2	37785	0.2
chr8_121137253_121137925	0.25	COL14A1	collagen, type XIV, alpha 1	237	0.96
chr6_130029394_130029625	0.25	ARHGAP18	Rho GTPase activating protein 18	1861	0.44
chr2_160142648_160143167	0.25	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1	156	0.97
chr4_85886471_85886934	0.25	WDFY3	WD repeat and FYVE domain containing 3	801	0.75
chrX_10126292_10126538	0.25	CLCN4	chloride channel, voltage-sensitive 4	73	0.98
chr5_38846105_38846894	0.25	OSMR	oncostatin M receptor	398	0.91
chrX_8699533_8700279	0.25	KAL1	Kallmann syndrome 1 sequence	321	0.94
chr17_70536173_70536521	0.25	ENSG00000200783	.	123944	0.06
chr16_86602293_86602507	0.25	RP11-463O9.5		1033	0.41
chr16_73809854_73810059	0.25	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	520717	0.0
chr22_30648782_30648933	0.25	LIF	leukemia inhibitory factor	6017	0.11
chr1_68024994_68025388	0.25	ENSG00000207504	.	18381	0.23
chr14_91282031_91282256	0.24	TTC7B	tetratricopeptide repeat domain 7B	618	0.82
chr22_44222171_44222754	0.24	RP3-388M5.9		14089	0.16
chr6_27637129_27637689	0.24	ENSG00000238648	.	38221	0.13
chr3_11179453_11179614	0.24	HRH1	histamine receptor H1	754	0.77
chr22_45899514_45899973	0.24	FBLN1	fibulin 1	817	0.67
chr19_38422631_38423016	0.24	SIPA1L3	signal-induced proliferation-associated 1 like 3	24955	0.15
chr1_47489778_47489953	0.24	CYP4X1	cytochrome P450, family 4, subfamily X, polypeptide 1	625	0.75
chr8_108508090_108508241	0.24	ANGPT1	angiopoietin 1	942	0.74
chr6_58148368_58148782	0.24	ENSG00000212017	.	893645	0.0
chr14_105147135_105147427	0.24	ENSG00000265291	.	3195	0.18
chr4_77752291_77752556	0.24	ENSG00000264124	.	22694	0.17
chr9_132539190_132539368	0.24	PTGES	prostaglandin E synthase	23953	0.12
chr11_44331338_44331543	0.24	ALX4	ALX homeobox 4	276	0.95
chr14_101292536_101293492	0.24	AL117190.2		2523	0.08
chr18_11149170_11149978	0.24	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr15_99092145_99092331	0.24	FAM169B	family with sequence similarity 169, member B	34627	0.21
chr11_119210307_119210719	0.24	C1QTNF5	C1q and tumor necrosis factor related protein 5	1080	0.28
chr16_4103676_4103973	0.24	RP11-462G12.4		21811	0.19
chr18_25757173_25757741	0.24	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	47	0.99
chr18_57364455_57364606	0.24	CCBE1	collagen and calcium binding EGF domains 1	82	0.93
chr7_42275735_42276044	0.24	GLI3	GLI family zinc finger 3	723	0.82
chr16_69959384_69959663	0.24	WWP2	WW domain containing E3 ubiquitin protein ligase 2	630	0.67
chr2_232531310_232531749	0.24	ENSG00000239202	.	20545	0.15
chr8_62625183_62625719	0.24	ASPH	aspartate beta-hydroxylase	1633	0.37
chr18_46460407_46461027	0.24	SMAD7	SMAD family member 7	14158	0.24
chr1_119530163_119530409	0.24	TBX15	T-box 15	142	0.97
chr6_6737313_6737878	0.24	LY86-AS1	LY86 antisense RNA 1	114591	0.06
chr5_72252365_72253035	0.24	FCHO2	FCH domain only 2	802	0.7
chr2_205410516_205411018	0.24	PARD3B	par-3 family cell polarity regulator beta	44	0.99
chr15_72529055_72529849	0.23	PKM	pyruvate kinase, muscle	5288	0.17
chr18_7566824_7567068	0.23	PTPRM	protein tyrosine phosphatase, receptor type, M	166	0.97
chr6_88427153_88427304	0.23	ENSG00000238628	.	3405	0.25
chr11_65666484_65666730	0.23	FOSL1	FOS-like antigen 1	1283	0.23
chr10_79397825_79398297	0.23	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	66	0.98
chr6_137310724_137311134	0.23	RP11-204P2.3		5378	0.23
chr3_123168721_123169253	0.23	ADCY5	adenylate cyclase 5	382	0.9
chr22_46472803_46473256	0.23	FLJ27365	hsa-mir-4763	3163	0.13
chr3_24719479_24719694	0.23	ENSG00000265028	.	156660	0.04
chr2_232229806_232230059	0.23	ENSG00000263641	.	2513	0.26
chr5_42423499_42423764	0.23	GHR	growth hormone receptor	248	0.96
chr16_19421704_19421876	0.23	TMC5	transmembrane channel-like 5	71	0.95
chr10_33620428_33620906	0.23	NRP1	neuropilin 1	2643	0.37
chr4_20255612_20255816	0.23	SLIT2	slit homolog 2 (Drosophila)	275	0.96
chr12_54379595_54379934	0.23	RP11-834C11.12		135	0.72
chr1_8762815_8763230	0.23	RERE	arginine-glutamic acid dipeptide (RE) repeats	256	0.95
chr8_89969714_89969944	0.23	RP11-586K2.1		257309	0.02
chr10_119303143_119303333	0.23	EMX2	empty spiracles homeobox 2	729	0.61
chr7_158441504_158441705	0.23	NCAPG2	non-SMC condensin II complex, subunit G2	18326	0.19
chr12_94134432_94134611	0.23	RP11-887P2.5		2922	0.31
chr8_57358039_57358590	0.23	RP11-17A4.2		52	0.69
chr7_80928308_80928745	0.23	AC005008.2	Uncharacterized protein	111420	0.08
chr16_73082076_73082698	0.23	ZFHX3	zinc finger homeobox 3	113	0.97
chr2_160654775_160654966	0.23	CD302	CD302 molecule	117	0.98
chr17_40933524_40933675	0.23	WNK4	WNK lysine deficient protein kinase 4	903	0.35
chr14_85999097_85999705	0.23	FLRT2	fibronectin leucine rich transmembrane protein 2	2829	0.32
chr12_727829_727980	0.23	NINJ2	ninjurin 2	8320	0.15
chr15_40530958_40531718	0.23	PAK6	p21 protein (Cdc42/Rac)-activated kinase 6	46	0.96
chr2_168151014_168151527	0.23	XIRP2	xin actin-binding repeat containing 2	107477	0.08
chr7_149193458_149193685	0.23	ZNF746	zinc finger protein 746	1253	0.51
chr8_55294582_55295235	0.23	ENSG00000244107	.	38120	0.17
chr10_100027009_100027207	0.23	LOXL4	lysyl oxidase-like 4	899	0.63

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.6	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.6	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.2	0.5	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.2	0.5	GO:0060437	lung growth(GO:0060437)
0.2	0.5	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.4	GO:0010842	retina layer formation(GO:0010842)
0.1	0.6	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.5	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.4	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.4	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.1	0.2	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1	0.2	GO:0010193	response to ozone(GO:0010193)
0.1	0.4	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.2	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.3	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.3	GO:0051451	myoblast migration(GO:0051451)
0.1	1.4	GO:0036294	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.1	0.3	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.3	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.5	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.4	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.3	GO:0070141	response to UV-A(GO:0070141)
0.1	0.3	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.1	0.2	GO:0060433	bronchus development(GO:0060433)
0.1	0.2	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1	0.2	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.1	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.2	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.1	GO:0021508	floor plate formation(GO:0021508)
0.1	0.2	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.5	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.3	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0045986	relaxation of smooth muscle(GO:0044557) negative regulation of smooth muscle contraction(GO:0045986) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.2	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.2	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.1	0.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.4	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.1	GO:0010159	specification of organ position(GO:0010159)
0.1	0.2	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.1	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.1	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.2	GO:0001973	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.1	0.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.1	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.3	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.1	GO:0032891	negative regulation of organic acid transport(GO:0032891)
0.1	0.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.1	0.2	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.1	1.2	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.3	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1	0.2	GO:0051608	histamine transport(GO:0051608)
0.1	0.2	GO:0015705	iodide transport(GO:0015705)
0.1	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.3	GO:0032288	myelin assembly(GO:0032288)
0.1	0.2	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.1	0.6	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.1	0.1	GO:0032682	negative regulation of chemokine production(GO:0032682) negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.3	GO:0008228	opsonization(GO:0008228)
0.1	0.1	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.1	0.2	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.0	0.1	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0019511	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.4	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0003323	type B pancreatic cell development(GO:0003323)
0.0	0.0	GO:0003309	type B pancreatic cell differentiation(GO:0003309)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.2	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.2	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.1	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0	0.2	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.2	GO:0060134	prepulse inhibition(GO:0060134)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.2	GO:0090103	cochlea morphogenesis(GO:0090103)
0.0	0.1	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.0	0.2	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.5	GO:0031114	regulation of microtubule depolymerization(GO:0031114)
0.0	0.2	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.2	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0021781	glial cell fate commitment(GO:0021781)
0.0	0.1	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0060405	regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.2	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0060068	vagina development(GO:0060068)
0.0	0.2	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0010800	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.1	GO:0010544	negative regulation of platelet activation(GO:0010544)
0.0	0.2	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0032610	interleukin-1 alpha production(GO:0032610)
0.0	0.2	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.8	GO:0045740	positive regulation of DNA replication(GO:0045740)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.2	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.3	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0021877	forebrain neuron fate commitment(GO:0021877)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.0	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.1	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0048532	anatomical structure arrangement(GO:0048532)
0.0	0.3	GO:0051966	regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.6	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.3	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.3	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.0	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:1903726	negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.1	GO:0007191	adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0	0.1	GO:0032967	positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0060707	trophoblast giant cell differentiation(GO:0060707)
0.0	0.4	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.0	GO:0035850	epithelial cell differentiation involved in kidney development(GO:0035850)
0.0	0.3	GO:0051303	chromosome localization(GO:0050000) establishment of chromosome localization(GO:0051303)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.3	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0032632	interleukin-3 production(GO:0032632)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.1	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0070245	positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.1	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.0	GO:0030540	female genitalia development(GO:0030540)
0.0	0.0	GO:0090102	cochlea development(GO:0090102)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0032049	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.3	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.0	GO:0050965	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.2	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0007045	cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041)
0.0	0.1	GO:0055093	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0	0.0	GO:0010934	macrophage cytokine production(GO:0010934) regulation of macrophage cytokine production(GO:0010935) positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.0	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.1	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0042220	response to cocaine(GO:0042220)
0.0	0.1	GO:0070841	inclusion body assembly(GO:0070841) aggresome assembly(GO:0070842)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0002551	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.0	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0	0.0	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.0	0.2	GO:0035024	negative regulation of Rho protein signal transduction(GO:0035024)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.3	GO:0008272	sulfate transport(GO:0008272)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.2	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0001516	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.0	GO:0045945	positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.0	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.0	0.0	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.5	GO:0070509	calcium ion import(GO:0070509)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.2	GO:0015695	organic cation transport(GO:0015695)
0.0	0.2	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.1	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.0	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.0	GO:0046475	phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.0	0.1	GO:0015853	adenine transport(GO:0015853)
0.0	0.1	GO:2000258	negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0060487	lung epithelial cell differentiation(GO:0060487)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.3	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.0	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0006007	glucose catabolic process(GO:0006007)
0.0	0.2	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.1	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.1	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.0	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.0	GO:0060996	dendritic spine development(GO:0060996)
0.0	0.1	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.0	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.0	GO:0032905	transforming growth factor beta1 production(GO:0032905) regulation of transforming growth factor beta1 production(GO:0032908)
0.0	0.1	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0	0.0	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.1	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0032026	response to magnesium ion(GO:0032026)
0.0	0.0	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0009251	glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.0	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0	1.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.4	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.0	0.1	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0051208	sequestering of calcium ion(GO:0051208)
0.0	0.0	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.1	GO:0045008	depyrimidination(GO:0045008)
0.0	0.1	GO:0014003	oligodendrocyte development(GO:0014003)
0.0	0.0	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.1	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0042504	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.4	GO:0006821	chloride transport(GO:0006821)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.3	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0007628	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.0	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0	0.2	GO:0050873	brown fat cell differentiation(GO:0050873)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0036230	granulocyte activation(GO:0036230)
0.0	0.0	GO:0010523	negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0	0.0	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.0	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0045117	azole transport(GO:0045117)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.7	GO:0016342	catenin complex(GO:0016342)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.2	GO:0044462	external encapsulating structure part(GO:0044462)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0001527	microfibril(GO:0001527)
0.1	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.1	0.5	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.2	GO:0031045	dense core granule(GO:0031045)
0.0	0.2	GO:0001740	Barr body(GO:0001740)
0.0	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	1.0	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.0	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	1.5	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0043205	fibril(GO:0043205)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.1	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.1	GO:0042581	specific granule(GO:0042581)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	4.4	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.2	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.4	GO:0005720	nuclear heterochromatin(GO:0005720)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.4	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	2.2	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.0	0.4	GO:0030018	Z disc(GO:0030018)
0.0	0.6	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.8	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.3	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.0	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.2	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0071986	Ragulator complex(GO:0071986)
0.0	1.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0097060	synaptic membrane(GO:0097060)
0.0	0.8	GO:0005925	focal adhesion(GO:0005925)
0.0	0.0	GO:0031527	filopodium membrane(GO:0031527)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.7	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.8	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.4	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1	0.3	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.1	0.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.3	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.6	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.3	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.4	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.6	GO:0017166	vinculin binding(GO:0017166)
0.1	0.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.3	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.1	0.3	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.1	0.2	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.3	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.7	GO:0031490	chromatin DNA binding(GO:0031490)
0.1	0.7	GO:0043394	proteoglycan binding(GO:0043394)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.2	GO:0031177	phosphopantetheine binding(GO:0031177)
0.1	0.2	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.5	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.2	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.2	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.4	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0031127	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.3	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.4	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.4	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	2.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.3	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0004351	glutamate decarboxylase activity(GO:0004351)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.4	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.2	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0071553	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0051378	serotonin binding(GO:0051378)
0.0	0.5	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.1	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	2.0	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.4	GO:0005518	collagen binding(GO:0005518)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.1	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.0	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0015333	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.0	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0005024	transmembrane receptor protein serine/threonine kinase activity(GO:0004675) transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	1.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.3	GO:0070330	aromatase activity(GO:0070330)
0.0	0.0	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.2	GO:0050699	WW domain binding(GO:0050699)
0.0	1.0	GO:0005179	hormone activity(GO:0005179)
0.0	0.0	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.5	GO:0008009	chemokine activity(GO:0008009)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0	0.0	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.0	GO:0030172	troponin C binding(GO:0030172)
0.0	0.3	GO:0032934	sterol binding(GO:0032934)
0.0	0.1	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.7	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.3	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.8	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.9	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.7	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.5	PID IGF1 PATHWAY	IGF1 pathway
0.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.7	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
1.0	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
1.1	PID BMP PATHWAY	BMP receptor signaling
4.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.9	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.4	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.2	PID ARF 3PATHWAY	Arf1 pathway
0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
3.0	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.4	PID FGF PATHWAY	FGF signaling pathway
0.2	PID AURORA A PATHWAY	Aurora A signaling
0.5	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
2.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.2	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	0.5	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	0.6	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.6	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	1.1	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	2.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.6	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.4	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL	Genes involved in Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.3	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.1	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling

Results for HESX1

Z-value: 1.66

Motif logo

Transcription factors associated with HESX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HESX1 motif across conditions

Conditions sorted by the z-value of the HESX1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HESX1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: