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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HIC1

Z-value: 2.51

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Transcription factors associated with HIC1

Gene Symbol	Gene ID	Gene Info
HIC1 Ensembl NCBI GeneCards UniProt	ENSG00000177374.8	HIC1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
HIC1	chr17_1956777_1956953	583	0.520406	-0.35	3.6e-01	Click!
HIC1	chr17_1961527_1961722	2020	0.156240	-0.24	5.3e-01	Click!
HIC1	chr17_1960560_1960711	1031	0.310092	-0.22	5.8e-01	Click!
HIC1	chr17_1956964_1957351	291	0.778601	-0.21	5.8e-01	Click!
HIC1	chr17_1961906_1962057	2377	0.137114	0.20	6.1e-01	Click!

Activity of the HIC1 motif across conditions

Conditions sorted by the z-value of the HIC1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_14924992_14926197	2.65	KAZN	kazrin, periplakin interacting protein	381	0.93
chr16_85203170_85204140	2.29	CTC-786C10.1		1227	0.55
chr20_55204347_55205219	2.25	TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	425	0.81
chr8_99439239_99439631	2.21	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2	185	0.95
chr2_54086905_54087527	1.88	GPR75-ASB3	GPR75-ASB3 readthrough	46	0.37
chr12_3308931_3310293	1.80	TSPAN9	tetraspanin 9	729	0.75
chr16_65155038_65155536	1.78	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	546	0.88
chr2_160918347_160919586	1.78	PLA2R1	phospholipase A2 receptor 1, 180kDa	155	0.98
chr11_94473290_94474384	1.73	RP11-867G2.8		316	0.92
chr13_110958781_110959436	1.71	COL4A1	collagen, type IV, alpha 1	370	0.6
chr1_39980649_39981517	1.69	RP11-69E11.4		9465	0.14
chr3_8809480_8810320	1.66	OXTR	oxytocin receptor	463	0.76
chr2_39893102_39893556	1.65	TMEM178A	transmembrane protein 178A	270	0.95
chr6_123317343_123317959	1.63	CLVS2	clavesin 2	183	0.97
chr11_70244216_70245100	1.63	CTTN	cortactin	11	0.53
chr8_687260_687856	1.62	ERICH1-AS1	ERICH1 antisense RNA 1	93	0.97
chr4_183369422_183369983	1.61	TENM3	teneurin transmembrane protein 3	450	0.89
chr14_62279468_62280189	1.56	SNAPC1	small nuclear RNA activating complex, polypeptide 1, 43kDa	50753	0.17
chr19_14315927_14317134	1.55	LPHN1	latrophilin 1	451	0.77
chr17_37856067_37857084	1.55	ERBB2	v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2	242	0.86
chr16_14396121_14396821	1.54	ENSG00000207639	.	1353	0.42
chr16_2521208_2521831	1.49	NTN3	netrin 3	19	0.93
chr17_64187141_64188685	1.44	CEP112	centrosomal protein 112kDa	60	0.98
chr2_96012468_96013004	1.40	KCNIP3	Kv channel interacting protein 3, calsenilin	260	0.94
chr11_119019412_119020504	1.40	ABCG4	ATP-binding cassette, sub-family G (WHITE), member 4	5	0.94
chr2_27717607_27718081	1.38	FNDC4	fibronectin type III domain containing 4	268	0.82
chr13_96296247_96296898	1.36	DZIP1	DAZ interacting zinc finger protein 1	372	0.89
chr17_43483002_43483407	1.36	ARHGAP27	Rho GTPase activating protein 27	96	0.95
chr3_64430574_64431219	1.34	PRICKLE2	prickle homolog 2 (Drosophila)	162	0.97
chr20_39994731_39995211	1.32	EMILIN3	elastin microfibril interfacer 3	496	0.81
chr8_49782515_49783288	1.30	SNAI2	snail family zinc finger 2	51087	0.18
chr11_75378366_75379067	1.30	MAP6	microtubule-associated protein 6	763	0.58
chr17_29036450_29037561	1.30	ENSG00000241631	.	7212	0.17
chr16_86542600_86543872	1.30	FOXF1	forkhead box F1	897	0.62
chr4_187644173_187644789	1.30	FAT1	FAT atypical cadherin 1	528	0.87
chr4_20255612_20255816	1.28	SLIT2	slit homolog 2 (Drosophila)	275	0.96
chr14_105830576_105830747	1.25	PACS2	phosphofurin acidic cluster sorting protein 2	18795	0.13
chr9_71939475_71940274	1.22	FAM189A2	family with sequence similarity 189, member A2	386	0.91
chr2_242497891_242499073	1.22	BOK-AS1	BOK antisense RNA 1	90	0.79
chrX_39548256_39548819	1.22	ENSG00000263730	.	28067	0.24
chr15_99640520_99640898	1.21	SYNM	synemin, intermediate filament protein	2289	0.24
chr6_147829082_147829740	1.21	SAMD5	sterile alpha motif domain containing 5	652	0.84
chr2_236403404_236403896	1.21	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	899	0.65
chr5_7396416_7397106	1.20	ADCY2	adenylate cyclase 2 (brain)	440	0.88
chr9_35489468_35490886	1.19	RUSC2	RUN and SH3 domain containing 2	53	0.97
chr6_46702576_46703631	1.19	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	24	0.97
chr12_312502_313284	1.18	RP11-283I3.2		85	0.95
chr17_9018882_9019405	1.18	NTN1	netrin 1	47109	0.15
chr15_51633704_51634417	1.17	GLDN	gliomedin	234	0.91
chr20_6032553_6033205	1.17	LRRN4	leucine rich repeat neuronal 4	1816	0.35
chr14_101034010_101035263	1.17	BEGAIN	brain-enriched guanylate kinase-associated	192	0.93
chr16_73082076_73082698	1.16	ZFHX3	zinc finger homeobox 3	113	0.97
chr16_15952283_15952487	1.16	MYH11	myosin, heavy chain 11, smooth muscle	1495	0.35
chr18_2906194_2907483	1.15	RP11-737O24.5		14126	0.16
chr18_6729547_6730123	1.15	ARHGAP28	Rho GTPase activating protein 28	14	0.5
chr8_8749576_8750657	1.14	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	1039	0.53
chr8_27491561_27492240	1.13	SCARA3	scavenger receptor class A, member 3	202	0.93
chr20_13976647_13977145	1.13	SEL1L2	sel-1 suppressor of lin-12-like 2 (C. elegans)	193	0.78
chr4_119273101_119273655	1.11	PRSS12	protease, serine, 12 (neurotrypsin, motopsin)	780	0.76
chr2_9347772_9348251	1.11	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	1117	0.65
chr2_159825200_159826543	1.11	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1	688	0.73
chr10_64564066_64565253	1.10	ADO	2-aminoethanethiol (cysteamine) dioxygenase	143	0.92
chr1_66258526_66259233	1.10	PDE4B	phosphodiesterase 4B, cAMP-specific	15	0.99
chr1_48462552_48463006	1.10	TRABD2B	TraB domain containing 2B	212	0.96
chr18_499765_500605	1.09	COLEC12	collectin sub-family member 12	537	0.79
chr5_113697124_113698006	1.09	KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	451	0.9
chr13_21295723_21296224	1.08	ENSG00000265710	.	18131	0.18
chr22_20119477_20120671	1.08	ZDHHC8	zinc finger, DHHC-type containing 8	603	0.53
chr9_140500205_140501463	1.07	ARRDC1	arrestin domain containing 1	679	0.56
chr20_30457693_30458808	1.06	DUSP15	dual specificity phosphatase 15	125	0.67
chrX_8699533_8700279	1.06	KAL1	Kallmann syndrome 1 sequence	321	0.94
chr3_123168721_123169253	1.05	ADCY5	adenylate cyclase 5	382	0.9
chr10_21462508_21463481	1.04	NEBL-AS1	NEBL antisense RNA 1	51	0.59
chr7_32110576_32110834	1.04	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	231	0.97
chr17_74581180_74582274	1.04	ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	483	0.62
chr3_55520023_55520469	1.03	WNT5A	wingless-type MMTV integration site family, member 5A	1085	0.48
chr4_6472295_6472644	1.03	PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	1704	0.48
chr19_41195400_41196566	1.02	NUMBL	numb homolog (Drosophila)-like	44	0.96
chr8_69242814_69243988	1.02	C8orf34	chromosome 8 open reading frame 34	56	0.82
chr16_67282110_67283381	1.02	SLC9A5	solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5	108	0.89
chr1_205648469_205649627	1.02	SLC45A3	solute carrier family 45, member 3	539	0.74
chr1_180881914_180882730	1.00	KIAA1614	KIAA1614	3	0.98
chr7_29846053_29846716	1.00	WIPF3	WAS/WASL interacting protein family, member 3	282	0.94
chr3_192126971_192127690	1.00	FGF12	fibroblast growth factor 12	492	0.87
chr10_35102956_35103650	0.99	PARD3	par-3 family cell polarity regulator	946	0.5
chr9_35791682_35791961	0.99	NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	330	0.75
chr11_126872809_126873319	0.99	KIRREL3-AS3	KIRREL3 antisense RNA 3	259	0.89
chr9_91793130_91793737	0.99	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	249	0.95
chr11_63530349_63531105	0.98	ENSG00000264519	.	34816	0.12
chr14_38063567_38064244	0.98	FOXA1	forkhead box A1	334	0.84
chr5_37839777_37839928	0.98	GDNF	glial cell derived neurotrophic factor	64	0.98
chr5_38845474_38846010	0.97	OSMR	oncostatin M receptor	218	0.96
chr17_76164337_76165654	0.97	SYNGR2	synaptogyrin 2	244	0.87
chr2_211089377_211090268	0.97	ACADL	acyl-CoA dehydrogenase, long chain	393	0.85
chr6_88875424_88876640	0.97	CNR1	cannabinoid receptor 1 (brain)	46	0.99
chr5_128796390_128797012	0.96	ADAMTS19-AS1	ADAMTS19 antisense RNA 1	319	0.77
chr1_34630625_34630811	0.96	CSMD2	CUB and Sushi multiple domains 2	157	0.94
chr16_691284_692401	0.96	FAM195A	family with sequence similarity 195, member A	29	0.92
chr5_76372662_76373578	0.96	ENSG00000238961	.	3276	0.17
chr14_73706275_73706778	0.95	PAPLN	papilin, proteoglycan-like sulfated glycoprotein	193	0.92
chrX_100545955_100546357	0.95	TAF7L	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	168	0.93
chr18_35146776_35147412	0.95	CELF4	CUGBP, Elav-like family member 4	1094	0.67
chr9_127539201_127540134	0.95	OLFML2A	olfactomedin-like 2A	117	0.95
chr13_44360523_44361050	0.95	ENOX1	ecto-NOX disulfide-thiol exchanger 1	258	0.95
chr2_36583449_36584760	0.95	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	490	0.89
chr11_110582275_110583137	0.95	ARHGAP20	Rho GTPase activating protein 20	67	0.99
chr1_167408487_167409140	0.95	RP11-104L21.2		19085	0.19
chr11_27740485_27740934	0.95	BDNF	brain-derived neurotrophic factor	585	0.82
chr6_87647008_87647409	0.95	HTR1E	5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled	184	0.97
chr17_10101159_10101987	0.95	GAS7	growth arrest-specific 7	295	0.92
chr11_118478413_118479735	0.94	PHLDB1	pleckstrin homology-like domain, family B, member 1	716	0.54
chr19_8400013_8400372	0.94	KANK3	KN motif and ankyrin repeat domains 3	7954	0.1
chr18_60263508_60264066	0.93	ENSG00000243549	.	54047	0.13
chr22_44727371_44727573	0.93	KIAA1644	KIAA1644	18741	0.22
chr6_125282837_125283421	0.93	RNF217	ring finger protein 217	562	0.67
chr16_51184635_51185066	0.93	SALL1	spalt-like transcription factor 1	302	0.89
chr10_15411519_15412658	0.93	FAM171A1	family with sequence similarity 171, member A1	970	0.7
chr12_31079520_31079921	0.92	TSPAN11	tetraspanin 11	38	0.99
chr5_173738719_173739174	0.92	CTC-229L21.1		138842	0.05
chr21_46825103_46825740	0.92	COL18A1	collagen, type XVIII, alpha 1	369	0.83
chr4_75718841_75720131	0.92	BTC	betacellulin	410	0.91
chr3_123752157_123752801	0.92	ENSG00000238512	.	28452	0.16
chr15_39873424_39874712	0.92	THBS1	thrombospondin 1	774	0.66
chr4_55096373_55096991	0.92	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	193	0.97
chr19_709173_709581	0.91	PALM	paralemmin	276	0.84
chrX_110038687_110039773	0.91	CHRDL1	chordin-like 1	56	0.99
chr6_46458824_46459774	0.91	RCAN2	regulator of calcineurin 2	200	0.78
chr2_120189452_120190154	0.91	TMEM37	transmembrane protein 37	358	0.88
chr6_78172796_78173983	0.91	HTR1B	5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled	101	0.99
chr4_146403033_146403938	0.91	SMAD1	SMAD family member 1	153	0.96
chr2_24232585_24233394	0.90	MFSD2B	major facilitator superfamily domain containing 2B	22	0.97
chr7_94536809_94537187	0.90	PPP1R9A	protein phosphatase 1, regulatory subunit 9A	11	0.99
chr7_149389592_149390001	0.89	KRBA1	KRAB-A domain containing 1	22076	0.2
chr14_105452072_105453062	0.89	C14orf79	chromosome 14 open reading frame 79	437	0.8
chr6_72129322_72130506	0.88	ENSG00000207827	.	16590	0.22
chr2_236401822_236402641	0.87	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	502	0.83
chr9_14312608_14313176	0.87	NFIB	nuclear factor I/B	774	0.71
chr1_934275_935357	0.87	HES4	hes family bHLH transcription factor 4	545	0.57
chr22_41633466_41634617	0.87	CHADL	chondroadherin-like	1584	0.26
chr2_236578912_236579455	0.87	AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	935	0.7
chr15_69590968_69591548	0.86	PAQR5	progestin and adipoQ receptor family member V	28	0.66
chr7_1705694_1706073	0.86	ELFN1	extracellular leucine-rich repeat and fibronectin type III domain containing 1	21872	0.17
chr6_56707814_56708209	0.86	DST	dystonin	2	0.95
chr5_72921316_72921781	0.86	ARHGEF28	Rho guanine nucleotide exchange factor (GEF) 28	435	0.84
chr7_150812372_150812612	0.86	AGAP3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	727	0.51
chr1_112532383_112532987	0.86	KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	908	0.69
chr16_88450130_88450579	0.86	ZNF469	zinc finger protein 469	43525	0.15
chr2_206546644_206547002	0.85	NRP2	neuropilin 2	401	0.91
chr2_128431846_128432683	0.85	LIMS2	LIM and senescent cell antigen-like domains 2	381	0.83
chr1_231298564_231298974	0.85	TRIM67	tripartite motif containing 67	53	0.98
chr5_159343463_159343902	0.85	ADRA1B	adrenoceptor alpha 1B	108	0.98
chr11_70962576_70962972	0.85	SHANK2	SH3 and multiple ankyrin repeat domains 2	849	0.72
chr12_80083529_80084306	0.85	PAWR	PRKC, apoptosis, WT1, regulator	57	0.98
chr10_72432567_72432920	0.85	ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	184	0.96
chr22_46546744_46547896	0.85	PPARA	peroxisome proliferator-activated receptor alpha	467	0.75
chr12_57522507_57523183	0.85	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	38	0.64
chr18_11149170_11149978	0.84	PIEZO2	piezo-type mechanosensitive ion channel component 2	987	0.72
chr16_19125601_19126223	0.84	ITPRIPL2	inositol 1,4,5-trisphosphate receptor interacting protein-like 2	658	0.65
chr1_62784626_62784933	0.84	KANK4	KN motif and ankyrin repeat domains 4	193	0.95
chr10_75670529_75671818	0.84	PLAU	plasminogen activator, urokinase	257	0.89
chr3_12329537_12330195	0.84	PPARG	peroxisome proliferator-activated receptor gamma	466	0.88
chr2_243030793_243031816	0.84	AC093642.5		460	0.62
chr16_74440490_74441404	0.84	CLEC18B	C-type lectin domain family 18, member B	14343	0.14
chr18_10454512_10454665	0.84	APCDD1	adenomatosis polyposis coli down-regulated 1	37	0.98
chr21_44495024_44495938	0.84	CBS	cystathionine-beta-synthase	460	0.8
chr2_201171688_201172904	0.83	SPATS2L	spermatogenesis associated, serine-rich 2-like	701	0.76
chr12_96183483_96184147	0.83	NTN4	netrin 4	89	0.96
chr7_108095607_108096848	0.83	NRCAM	neuronal cell adhesion molecule	538	0.84
chr14_38052851_38053204	0.83	FOXA1	forkhead box A1	11212	0.23
chr15_83875578_83876391	0.83	HDGFRP3	Hepatoma-derived growth factor-related protein 3	786	0.64
chr1_40236298_40236878	0.82	OXCT2	3-oxoacid CoA transferase 2	432	0.76
chr8_23260918_23261191	0.82	LOXL2	lysyl oxidase-like 2	535	0.78
chr4_4388085_4389202	0.82	NSG1	Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.	189	0.96
chr3_142607235_142608274	0.82	PCOLCE2	procollagen C-endopeptidase enhancer 2	13	0.98
chr19_460012_460518	0.82	SHC2	SHC (Src homology 2 domain containing) transforming protein 2	731	0.5
chr9_104248314_104249564	0.82	TMEM246	transmembrane protein 246	460	0.79
chr19_45843770_45844284	0.81	KLC3	kinesin light chain 3	5	0.95
chr19_46270942_46271877	0.80	AC074212.5		236	0.49
chr6_19838575_19839711	0.80	RP1-167F1.2		168	0.95
chr1_119543832_119544021	0.80	TBX15	T-box 15	11747	0.25
chr9_90588787_90589959	0.80	CDK20	cyclin-dependent kinase 20	29	0.98
chr4_87515623_87516236	0.80	PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	44	0.93
chr4_24913981_24914389	0.80	CCDC149	coiled-coil domain containing 149	323	0.94
chr19_1566819_1567637	0.80	MEX3D	mex-3 RNA binding family member D	301	0.76
chr4_20256302_20256578	0.79	SLIT2	slit homolog 2 (Drosophila)	103	0.98
chr14_67999720_68000517	0.79	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1	100	0.78
chr4_5053247_5053862	0.79	STK32B	serine/threonine kinase 32B	385	0.9
chr10_71562195_71562717	0.79	COL13A1	collagen, type XIII, alpha 1	276	0.92
chr5_31193803_31195028	0.78	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	558	0.85
chr13_27131903_27132772	0.78	WASF3	WAS protein family, member 3	450	0.89
chr16_1664599_1665551	0.78	CRAMP1L	Crm, cramped-like (Drosophila)	434	0.69
chr3_55522456_55523178	0.78	WNT5A-AS1	WNT5A antisense RNA 1	1090	0.43
chr17_79373625_79374766	0.78	ENSG00000266392	.	383	0.6
chr5_131562588_131563831	0.78	P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	138	0.96
chr21_45139141_45140358	0.78	PDXK	pyridoxal (pyridoxine, vitamin B6) kinase	756	0.66
chr6_105627392_105627796	0.78	POPDC3	popeye domain containing 3	141	0.93
chrX_50556610_50557434	0.78	SHROOM4	shroom family member 4	22	0.99
chr2_45395914_45396553	0.78	SIX2	SIX homeobox 2	159664	0.04
chr16_51185618_51185964	0.78	SALL1	spalt-like transcription factor 1	605	0.76
chr15_83316430_83317127	0.77	CPEB1	cytoplasmic polyadenylation element binding protein 1	50	0.76

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HIC1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.8	2.4	GO:0060677	ureteric bud elongation(GO:0060677)
0.7	2.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.7	3.5	GO:0060206	estrous cycle phase(GO:0060206)
0.6	1.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.6	2.3	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.5	1.4	GO:0070141	response to UV-A(GO:0070141)
0.4	2.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.4	1.2	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.4	1.2	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.4	0.8	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.4	0.8	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.4	1.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.4	1.1	GO:0033603	positive regulation of dopamine secretion(GO:0033603)
0.4	1.1	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4	0.4	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.4	0.4	GO:0072179	nephric duct formation(GO:0072179)
0.3	0.3	GO:0072047	proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.3	1.7	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.3	0.3	GO:0090103	cochlea morphogenesis(GO:0090103)
0.3	1.3	GO:0072070	loop of Henle development(GO:0072070)
0.3	1.7	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.3	1.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.3	1.0	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.3	1.0	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.3	0.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.3	2.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.3	0.9	GO:0009648	photoperiodism(GO:0009648)
0.3	0.9	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.3	0.9	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.3	0.3	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.3	0.9	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.3	0.3	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048)
0.3	0.9	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.3	0.8	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.3	1.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.3	1.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.1	GO:0008218	bioluminescence(GO:0008218)
0.3	0.5	GO:0001880	Mullerian duct regression(GO:0001880)
0.3	0.3	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.3	0.8	GO:0030241	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.3	1.3	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.3	0.3	GO:0061364	Roundabout signaling pathway(GO:0035385) apoptotic process involved in luteolysis(GO:0061364)
0.2	0.7	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	1.7	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	1.2	GO:0021873	forebrain neuroblast division(GO:0021873)
0.2	0.7	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.2	0.5	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.2	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.2	0.7	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.2	0.7	GO:0022605	oogenesis stage(GO:0022605)
0.2	0.7	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	0.9	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.2	0.2	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.2	0.6	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.6	GO:0016080	synaptic vesicle targeting(GO:0016080)
0.2	0.4	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.2	1.6	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.2	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.8	GO:0021978	telencephalon regionalization(GO:0021978)
0.2	0.6	GO:0051451	myoblast migration(GO:0051451)
0.2	0.4	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.2	0.2	GO:0050910	detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.2	0.6	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.2	0.4	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.2	0.6	GO:0035588	adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.2	0.6	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.2	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	1.2	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.2	1.4	GO:0036296	response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.2	0.2	GO:2000980	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2	0.2	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.2	0.5	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.2	0.5	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	0.5	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2	0.2	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.2	0.2	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.2	1.2	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.2	0.5	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2	0.3	GO:0051541	elastin metabolic process(GO:0051541)
0.2	0.5	GO:0045112	integrin biosynthetic process(GO:0045112)
0.2	0.5	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.2	0.3	GO:0003148	outflow tract septum morphogenesis(GO:0003148)
0.2	1.0	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2	0.6	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.2	0.3	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.2	0.8	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2	0.5	GO:0007412	axon target recognition(GO:0007412)
0.2	0.2	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.2	0.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.2	0.8	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.2	0.8	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.2	0.3	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.1	0.4	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.6	GO:0016198	axon choice point recognition(GO:0016198)
0.1	0.6	GO:0030146	obsolete diuresis(GO:0030146)
0.1	0.1	GO:0060841	venous blood vessel development(GO:0060841)
0.1	0.6	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	2.0	GO:0032400	melanosome localization(GO:0032400)
0.1	0.6	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.4	GO:0032060	bleb assembly(GO:0032060)
0.1	0.7	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.1	1.0	GO:1900006	positive regulation of dendrite morphogenesis(GO:0050775) positive regulation of dendrite development(GO:1900006)
0.1	0.3	GO:0048865	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.1	0.7	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.4	GO:0001705	ectoderm formation(GO:0001705)
0.1	0.4	GO:0021781	glial cell fate commitment(GO:0021781)
0.1	0.4	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.5	GO:0032288	myelin assembly(GO:0032288)
0.1	0.4	GO:0008215	spermine metabolic process(GO:0008215)
0.1	0.8	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1	0.9	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.1	GO:0006910	phagocytosis, recognition(GO:0006910)
0.1	0.3	GO:0060214	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.1	0.4	GO:0046886	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.1	0.9	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.2	GO:0060438	trachea development(GO:0060438)
0.1	0.5	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.2	GO:0060065	uterus development(GO:0060065)
0.1	0.7	GO:0006837	serotonin transport(GO:0006837)
0.1	0.5	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	1.5	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.1	0.5	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.5	GO:0018101	protein citrullination(GO:0018101)
0.1	0.2	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.1	0.2	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1	0.6	GO:0002068	glandular epithelial cell development(GO:0002068)
0.1	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.2	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.1	0.5	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.5	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.1	2.1	GO:0006182	cGMP biosynthetic process(GO:0006182)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	1.6	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.1	0.5	GO:0007619	courtship behavior(GO:0007619)
0.1	0.2	GO:0061430	bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1	1.1	GO:0009650	UV protection(GO:0009650)
0.1	0.4	GO:0001757	somite specification(GO:0001757)
0.1	0.4	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.3	GO:0045007	depurination(GO:0045007)
0.1	0.4	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.4	GO:0060992	response to fungicide(GO:0060992)
0.1	0.1	GO:0030252	growth hormone secretion(GO:0030252)
0.1	0.2	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.1	1.5	GO:0051350	negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)
0.1	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	1.1	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	0.5	GO:0046184	aldehyde biosynthetic process(GO:0046184)
0.1	0.4	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.3	GO:0043137	DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.1	0.5	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.1	1.5	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.1	0.6	GO:0015904	tetracycline transport(GO:0015904)
0.1	2.6	GO:0071804	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1	0.4	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.4	GO:0051014	actin filament severing(GO:0051014)
0.1	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.3	GO:0051895	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.1	0.7	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1	0.3	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.5	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1	0.1	GO:0002066	columnar/cuboidal epithelial cell development(GO:0002066)
0.1	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.1	0.3	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.8	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.3	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.2	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.1	0.5	GO:0032026	response to magnesium ion(GO:0032026)
0.1	0.4	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.4	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.1	0.1	GO:0060592	mammary gland formation(GO:0060592)
0.1	0.3	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1	0.2	GO:0030800	negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of purine nucleotide biosynthetic process(GO:1900372) negative regulation of purine nucleotide metabolic process(GO:1900543)
0.1	0.3	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.4	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.3	GO:0016246	RNA interference(GO:0016246)
0.1	1.8	GO:0006940	regulation of smooth muscle contraction(GO:0006940)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.1	GO:0048485	sympathetic nervous system development(GO:0048485)
0.1	1.6	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.2	GO:0060456	positive regulation of digestive system process(GO:0060456)
0.1	0.4	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.4	GO:0007413	axonal fasciculation(GO:0007413)
0.1	0.5	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.1	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.4	GO:0008347	glial cell migration(GO:0008347)
0.1	0.3	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.1	0.5	GO:0015802	basic amino acid transport(GO:0015802)
0.1	0.3	GO:0071800	podosome assembly(GO:0071800)
0.1	0.2	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.5	GO:0006477	protein sulfation(GO:0006477)
0.1	0.9	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.2	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.1	0.4	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.4	GO:0015824	proline transport(GO:0015824)
0.1	9.4	GO:0006813	potassium ion transport(GO:0006813)
0.1	0.7	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.1	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.1	0.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.3	GO:1903318	negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.1	0.7	GO:0046697	decidualization(GO:0046697)
0.1	0.3	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
0.1	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.1	GO:0045683	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617) negative regulation of epidermis development(GO:0045683)
0.1	0.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	2.9	GO:0031424	keratinization(GO:0031424)
0.1	0.1	GO:0042640	anagen(GO:0042640)
0.1	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.1	1.1	GO:0001539	cilium or flagellum-dependent cell motility(GO:0001539)
0.1	0.1	GO:0018126	protein hydroxylation(GO:0018126)
0.1	0.5	GO:0008038	neuron recognition(GO:0008038)
0.1	0.2	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	0.9	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.1	0.1	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.3	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.1	0.4	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.1	0.1	GO:0050919	negative chemotaxis(GO:0050919)
0.1	0.1	GO:0021514	ventral spinal cord interneuron differentiation(GO:0021514) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.1	1.8	GO:0046847	filopodium assembly(GO:0046847)
0.1	0.4	GO:0007617	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1	0.3	GO:0007549	dosage compensation(GO:0007549)
0.1	0.7	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.1	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.1	0.2	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.1	0.2	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.1	0.1	GO:0090175	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1	0.5	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.4	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.1	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.1	0.6	GO:0014003	oligodendrocyte development(GO:0014003)
0.1	0.2	GO:0007616	long-term memory(GO:0007616)
0.1	0.1	GO:1901374	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.1	0.2	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1	0.4	GO:0030325	adrenal gland development(GO:0030325)
0.1	0.3	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	1.4	GO:2000181	negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.1	0.6	GO:0021987	cerebral cortex development(GO:0021987)
0.1	0.3	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1	7.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.2	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.1	0.1	GO:0060013	righting reflex(GO:0060013)
0.1	0.3	GO:0015732	prostaglandin transport(GO:0015732)
0.1	0.6	GO:0007530	sex determination(GO:0007530)
0.1	0.3	GO:0002070	epithelial cell maturation(GO:0002070)
0.1	0.1	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1	1.0	GO:0033344	cholesterol efflux(GO:0033344)
0.1	0.2	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1	0.6	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.1	0.3	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	0.2	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.1	0.1	GO:0001893	maternal placenta development(GO:0001893)
0.1	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.2	GO:0021854	hypothalamus development(GO:0021854)
0.1	0.1	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.1	0.5	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.2	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.2	GO:0090205	positive regulation of cholesterol metabolic process(GO:0090205)
0.1	0.2	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.5	GO:0007141	male meiosis I(GO:0007141)
0.1	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.4	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.1	GO:0032233	positive regulation of actin filament bundle assembly(GO:0032233)
0.1	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.1	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.1	0.2	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.1	GO:0044803	multi-organism membrane organization(GO:0044803)
0.1	0.2	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.1	0.5	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.7	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.3	GO:0060351	cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1	0.1	GO:0031652	regulation of heat generation(GO:0031650) positive regulation of heat generation(GO:0031652)
0.1	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0090218	positive regulation of lipid kinase activity(GO:0090218)
0.0	0.3	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	1.4	GO:0001764	neuron migration(GO:0001764)
0.0	0.4	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.3	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.3	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.2	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.2	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.3	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.2	GO:0009188	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.2	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.2	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.8	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.4	GO:0001709	cell fate determination(GO:0001709)
0.0	0.0	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	1.4	GO:0007588	excretion(GO:0007588)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	2.9	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.1	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117) positive regulation of protein depolymerization(GO:1901881)
0.0	0.3	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0007622	rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.4	GO:0003143	heart looping(GO:0001947) embryonic heart tube morphogenesis(GO:0003143) determination of heart left/right asymmetry(GO:0061371)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0097479	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.2	GO:0001960	negative regulation of cytokine-mediated signaling pathway(GO:0001960)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.2	GO:0006991	response to sterol depletion(GO:0006991)
0.0	0.0	GO:0010092	specification of organ identity(GO:0010092)
0.0	0.1	GO:0044254	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.2	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.3	GO:0006939	smooth muscle contraction(GO:0006939)
0.0	0.1	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.1	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.3	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0043691	reverse cholesterol transport(GO:0043691)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0021517	ventral spinal cord development(GO:0021517)
0.0	9.0	GO:0007409	axonogenesis(GO:0007409)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.2	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.3	GO:0032740	positive regulation of interleukin-17 production(GO:0032740)
0.0	1.0	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.3	GO:0014823	response to activity(GO:0014823)
0.0	0.1	GO:0002281	macrophage activation involved in immune response(GO:0002281)
0.0	0.2	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	2.4	GO:0007266	Rho protein signal transduction(GO:0007266)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0015793	glycerol transport(GO:0015793)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.2	GO:0098743	cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.0	0.6	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.2	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.2	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.2	GO:0031345	negative regulation of cell projection organization(GO:0031345)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.2	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.3	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.2	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.2	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
0.0	0.2	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.0	0.2	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.2	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0002369	T cell cytokine production(GO:0002369) regulation of T cell cytokine production(GO:0002724)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.2	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.0	GO:0003309	type B pancreatic cell differentiation(GO:0003309)
0.0	0.1	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.3	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.0	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0	0.2	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.0	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.2	GO:0007566	embryo implantation(GO:0007566)
0.0	0.1	GO:0070193	synaptonemal complex assembly(GO:0007130) synaptonemal complex organization(GO:0070193)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	1.7	GO:0006814	sodium ion transport(GO:0006814)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0043324	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0043954	cellular component maintenance(GO:0043954)
0.0	0.0	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.0	GO:0046928	regulation of neurotransmitter secretion(GO:0046928) regulation of neurotransmitter transport(GO:0051588)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.2	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.2	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.2	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.0	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.2	GO:0070371	ERK1 and ERK2 cascade(GO:0070371)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0097154	GABAergic neuron differentiation(GO:0097154)
0.0	0.1	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.0	GO:0042428	serotonin metabolic process(GO:0042428) primary amino compound metabolic process(GO:1901160)
0.0	0.1	GO:0050885	neuromuscular process controlling balance(GO:0050885)
0.0	0.4	GO:0006821	chloride transport(GO:0006821)
0.0	0.0	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0071635	negative regulation of transforming growth factor beta production(GO:0071635)
0.0	0.0	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.2	GO:0042274	ribosomal small subunit biogenesis(GO:0042274)
0.0	0.3	GO:0042472	inner ear morphogenesis(GO:0042472)
0.0	0.0	GO:0021675	nerve development(GO:0021675)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.1	GO:0009304	tRNA transcription(GO:0009304) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0032634	interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0	0.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.2	GO:0046329	negative regulation of JNK cascade(GO:0046329)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0015893	drug transport(GO:0015893)
0.0	0.2	GO:1901222	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.0	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0	0.0	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.0	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.0	GO:0010455	positive regulation of cell fate commitment(GO:0010455)
0.0	0.4	GO:0007605	sensory perception of sound(GO:0007605)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.6	GO:0005587	collagen type IV trimer(GO:0005587)
0.3	2.0	GO:0010369	chromocenter(GO:0010369)
0.3	0.9	GO:0043083	synaptic cleft(GO:0043083)
0.3	1.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	0.9	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.3	0.3	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3	0.8	GO:0043259	laminin-10 complex(GO:0043259)
0.3	1.1	GO:0043218	compact myelin(GO:0043218)
0.2	1.0	GO:0030056	hemidesmosome(GO:0030056)
0.2	1.3	GO:0001527	microfibril(GO:0001527)
0.2	0.6	GO:0005588	collagen type V trimer(GO:0005588)
0.2	0.7	GO:0030673	axolemma(GO:0030673)
0.2	0.5	GO:0033270	paranode region of axon(GO:0033270)
0.2	0.5	GO:0070852	cell body fiber(GO:0070852)
0.2	0.5	GO:0042597	outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.2	1.3	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.2	4.2	GO:0005581	collagen trimer(GO:0005581)
0.1	2.4	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.7	GO:0005916	fascia adherens(GO:0005916)
0.1	0.4	GO:0002141	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.5	GO:0005606	laminin-1 complex(GO:0005606)
0.1	2.9	GO:0001533	cornified envelope(GO:0001533)
0.1	1.1	GO:0031941	filamentous actin(GO:0031941)
0.1	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.6	GO:0071437	invadopodium(GO:0071437)
0.1	0.7	GO:0005652	nuclear lamina(GO:0005652)
0.1	0.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.1	2.5	GO:0005884	actin filament(GO:0005884)
0.1	0.1	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.1	23.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.5	GO:0000805	X chromosome(GO:0000805)
0.1	7.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.1	1.1	GO:0005858	axonemal dynein complex(GO:0005858)
0.1	0.6	GO:0030686	90S preribosome(GO:0030686)
0.1	0.2	GO:0061202	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.1	0.2	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.3	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.4	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.5	GO:0032589	neuron projection membrane(GO:0032589)
0.1	0.3	GO:0002102	podosome(GO:0002102)
0.1	1.7	GO:0005902	microvillus(GO:0005902)
0.1	1.4	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.2	GO:0016460	myosin II complex(GO:0016460)
0.1	0.6	GO:0030118	clathrin coat(GO:0030118)
0.1	0.5	GO:0043034	costamere(GO:0043034)
0.1	0.1	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	3.3	GO:0030426	growth cone(GO:0030426)
0.1	0.6	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	1.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	1.4	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.1	0.4	GO:0008290	F-actin capping protein complex(GO:0008290)
0.1	0.6	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	2.4	GO:0031012	extracellular matrix(GO:0031012)
0.0	3.6	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.3	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.3	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.3	GO:0016011	dystroglycan complex(GO:0016011)
0.0	0.6	GO:0042383	sarcolemma(GO:0042383)
0.0	2.3	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.5	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	1.4	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0031143	pseudopodium(GO:0031143)
0.0	0.2	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	20.4	GO:0005615	extracellular space(GO:0005615)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.5	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.3	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.6	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	2.3	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.4	GO:0005811	lipid particle(GO:0005811)
0.0	1.1	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.4	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	1.9	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.5	GO:0005922	connexon complex(GO:0005922)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	2.4	GO:0045202	synapse(GO:0045202)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.8	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.4	GO:0031514	motile cilium(GO:0031514)
0.0	0.2	GO:0031526	brush border membrane(GO:0031526)
0.0	1.4	GO:0036477	somatodendritic compartment(GO:0036477)
0.0	14.1	GO:0005887	integral component of plasma membrane(GO:0005887)
0.0	0.6	GO:0030136	clathrin-coated vesicle(GO:0030136)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.9	GO:0001726	ruffle(GO:0001726)
0.0	0.2	GO:0032432	actin filament bundle(GO:0032432)
0.0	0.0	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0031091	platelet alpha granule(GO:0031091)
0.0	0.0	GO:0001939	female pronucleus(GO:0001939)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	12.5	GO:0005576	extracellular region(GO:0005576)
0.0	0.9	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	2.8	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.8	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.0	GO:0005771	multivesicular body(GO:0005771)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.5	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.0	2.9	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.8	3.0	GO:0048495	Roundabout binding(GO:0048495)
0.7	2.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.6	1.7	GO:0003680	AT DNA binding(GO:0003680)
0.5	3.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.5	4.0	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5	1.4	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.5	1.4	GO:0070324	thyroid hormone binding(GO:0070324)
0.4	1.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.4	1.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.4	1.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	1.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3	1.0	GO:0008061	chitin binding(GO:0008061)
0.3	1.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.3	1.6	GO:0070700	BMP receptor binding(GO:0070700)
0.3	1.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.3	0.9	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.3	5.3	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3	0.9	GO:0050544	arachidonic acid binding(GO:0050544)
0.3	1.2	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.3	1.5	GO:0005000	vasopressin receptor activity(GO:0005000)
0.3	1.5	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.3	1.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	2.4	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	0.8	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.2	0.7	GO:0005042	netrin receptor activity(GO:0005042)
0.2	0.9	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2	0.7	GO:0004936	alpha-adrenergic receptor activity(GO:0004936)
0.2	2.6	GO:0051010	microtubule plus-end binding(GO:0051010)
0.2	0.5	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	0.7	GO:0019215	intermediate filament binding(GO:0019215)
0.2	0.4	GO:0030955	potassium ion binding(GO:0030955)
0.2	2.0	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	1.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2	1.9	GO:0051378	serotonin binding(GO:0051378)
0.2	0.4	GO:0048018	receptor agonist activity(GO:0048018)
0.2	0.4	GO:0043495	protein anchor(GO:0043495)
0.2	0.6	GO:0070052	collagen V binding(GO:0070052)
0.2	1.7	GO:0015643	toxic substance binding(GO:0015643)
0.2	1.3	GO:0005110	frizzled-2 binding(GO:0005110)
0.2	0.6	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.2	0.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.2	4.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.2	0.5	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.2	0.5	GO:0035198	miRNA binding(GO:0035198)
0.2	0.5	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.2	0.5	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.2	1.9	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.2	0.3	GO:0030172	troponin C binding(GO:0030172)
0.2	1.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.2	1.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.2	1.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.2	0.6	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.1	0.7	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	10.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.6	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.1	0.7	GO:0008517	folic acid transporter activity(GO:0008517)
0.1	0.8	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.8	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	2.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.7	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1	0.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.7	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.0	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	1.3	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.1	1.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.5	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.9	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.6	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.5	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.5	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.5	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.1	0.8	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1	1.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	1.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.1	1.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	3.7	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.4	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1	0.3	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.5	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.1	0.8	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.4	GO:0031404	chloride ion binding(GO:0031404)
0.1	0.3	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.3	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	0.7	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	1.0	GO:0030553	cGMP binding(GO:0030553)
0.1	0.3	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.5	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.7	GO:0004983	neuropeptide Y receptor activity(GO:0004983)
0.1	0.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.5	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.4	GO:0031013	troponin I binding(GO:0031013)
0.1	1.6	GO:0008066	glutamate receptor activity(GO:0008066)
0.1	0.8	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.3	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.5	GO:0035240	dopamine binding(GO:0035240)
0.1	1.9	GO:0005272	sodium channel activity(GO:0005272)
0.1	0.4	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.6	GO:0017166	vinculin binding(GO:0017166)
0.1	0.9	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.6	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.1	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	9.2	GO:0005267	potassium channel activity(GO:0005267)
0.1	0.5	GO:0051635	obsolete bacterial cell surface binding(GO:0051635)
0.1	0.2	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1	0.1	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.1	0.2	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	0.3	GO:0004064	arylesterase activity(GO:0004064)
0.1	3.7	GO:0051015	actin filament binding(GO:0051015)
0.1	1.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.2	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.8	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.7	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	1.7	GO:0005518	collagen binding(GO:0005518)
0.1	0.4	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	0.9	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.7	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.1	0.3	GO:0008131	primary amine oxidase activity(GO:0008131)
0.1	0.5	GO:0005109	frizzled binding(GO:0005109)
0.1	0.4	GO:0034235	GPI anchor binding(GO:0034235)
0.1	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.3	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	8.5	GO:0008083	growth factor activity(GO:0008083)
0.1	0.5	GO:0008242	omega peptidase activity(GO:0008242)
0.1	0.2	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.1	0.8	GO:0008373	sialyltransferase activity(GO:0008373)
0.1	0.2	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.2	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	0.2	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	0.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	0.2	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.1	0.9	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.3	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821)
0.1	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.2	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.4	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.6	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.4	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.7	GO:0045296	cadherin binding(GO:0045296)
0.0	0.3	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.0	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.3	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.3	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.7	GO:0004890	GABA-A receptor activity(GO:0004890)
0.0	0.5	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.4	GO:0019894	kinesin binding(GO:0019894)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0030881	beta-2-microglobulin binding(GO:0030881)
0.0	0.5	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.0	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.4	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.0	0.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.3	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.2	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.0	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	3.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	9.2	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	2.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	1.0	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0016934	inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0043208	glycosphingolipid binding(GO:0043208)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0004629	phospholipase C activity(GO:0004629)
0.0	0.1	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.0	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.6	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0042165	neurotransmitter binding(GO:0042165)
0.0	0.1	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.0	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.3	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.4	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.0	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.2	GO:0070405	ammonium ion binding(GO:0070405)
0.0	0.1	GO:0015651	quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.7	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	1.2	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	2.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.2	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.2	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.9	GO:0005179	hormone activity(GO:0005179)
0.0	0.1	GO:0080031	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.0	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	2.8	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.2	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.9	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.0	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0019959	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.8	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.1	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	4.9	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	4.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	10.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.2	0.3	ST GA13 PATHWAY	G alpha 13 Pathway
0.2	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	2.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.7	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.5	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.4	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	2.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	15.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	3.2	PID BMP PATHWAY	BMP receptor signaling
0.1	0.9	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	2.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	1.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	0.9	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.1	0.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	0.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	0.2	PID REELIN PATHWAY	Reelin signaling pathway
0.1	11.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	7.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	1.0	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.6	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.5	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	10.9	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.6	PID AURORA A PATHWAY	Aurora A signaling
0.0	1.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.0	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0	0.2	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.2	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	4.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	2.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	2.6	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.2	2.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	2.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.2	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.2	5.4	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	9.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	2.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	0.6	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	1.8	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.4	REACTOME GPCR LIGAND BINDING	Genes involved in GPCR ligand binding
0.1	5.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.8	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	0.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	3.1	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.4	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	2.1	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.9	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	1.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	1.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	0.6	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	0.2	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	1.0	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1	1.0	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	1.4	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	1.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	0.2	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.1	2.6	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	0.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	0.5	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.1	0.8	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.1	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1	0.6	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1	1.1	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.2	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1	0.4	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	2.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.7	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.6	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	1.2	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.7	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.0	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.6	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	2.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.7	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.6	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.4	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.5	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	2.9	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.3	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.0	0.0	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.0	3.7	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.4	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0	0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.1	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport