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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HINFP

Z-value: 1.67

Motif logo

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Transcription factors associated with HINFP

Gene Symbol Gene ID Gene Info
HINFP
ENSG00000172273.8 histone H4 transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_118992546_118993053HINFP4730.6024570.836.0e-03Click!
chr11_118993078_118993278HINFP8520.3558410.752.1e-02Click!
chr11_118992318_118992526HINFP960.9181250.732.4e-02Click!
chr11_118991757_118992004HINFP4170.6519090.608.9e-02Click!

Activity of the HINFP motif across conditions

Conditions sorted by the z-value of the HINFP motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_712290_712543 1.49 ENOSF1
 enolase superfamily member 1
 128
 0.93
chr12_122016646_122016834 0.59 KDM2B
 lysine (K)-specific demethylase 2B
 809
 0.64
chr2_131485272_131485551 0.53 GPR148
 G protein-coupled receptor 148
 1232
 0.38
chr20_25676639_25676790 0.51 ZNF337
 zinc finger protein 337
 763
 0.66
chr1_1510057_1510208 0.51 SSU72
 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)
 117
 0.63
chr5_92915594_92915963 0.49 ENSG00000237187
 .
 935
 0.59
chr4_171011215_171011473 0.48 AADAT
 aminoadipate aminotransferase
 21
 0.99
chr15_77712259_77712435 0.46 PEAK1
 pseudopodium-enriched atypical kinase 1
 95
 0.84
chr22_39930636_39930908 0.45 RPS19BP1
 ribosomal protein S19 binding protein 1
 1912
 0.27
chr10_124220456_124220833 0.45 HTRA1
 HtrA serine peptidase 1
 397
 0.85
chr4_122617846_122618120 0.44 ANXA5
 annexin A5
 134
 0.97
chr12_133264537_133264752 0.44 PXMP2
 peroxisomal membrane protein 2, 22kDa
 9
 0.48
chrX_134232377_134232653 0.44 FAM127B
 family with sequence similarity 127, member B
 46310
 0.12
chr8_145024226_145024570 0.43 PLEC
 plectin
 646
 0.55
chrX_40944624_40944775 0.42 USP9X
 ubiquitin specific peptidase 9, X-linked
 189
 0.97
chr8_12989314_12989523 0.42 DLC1
 deleted in liver cancer 1
 1565
 0.46
chr3_107243761_107243927 0.42 BBX
 bobby sox homolog (Drosophila)
 394
 0.92
chr1_20208913_20209174 0.41 OTUD3
 OTU domain containing 3
 37
 0.98
chr10_131762270_131762646 0.41 EBF3
 early B-cell factor 3
 353
 0.93
chr1_99730395_99730700 0.41 LPPR4
 Lipid phosphate phosphatase-related protein type 4
 699
 0.82
chr11_27015895_27016133 0.40 FIBIN
 fin bud initiation factor homolog (zebrafish)
 386
 0.91
chr15_75494284_75494452 0.40 C15orf39
 chromosome 15 open reading frame 39
 150
 0.93
chr22_41957116_41957349 0.39 CSDC2
 cold shock domain containing C2, RNA binding
 465
 0.74
chr9_98278777_98278941 0.39 PTCH1
 patched 1
 388
 0.82
chr2_27530376_27530527 0.39 UCN
 urocortin
 862
 0.37
chr1_197115203_197115435 0.39 ASPM
 asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
 505
 0.83
chr4_81124101_81124367 0.38 PRDM8
 PR domain containing 8
 5576
 0.24
chr6_56819850_56820001 0.38 BEND6
 BEN domain containing 6
 1
 0.9
chr4_25235722_25235933 0.38 PI4K2B
 phosphatidylinositol 4-kinase type 2 beta
 230
 0.95
chr22_42949413_42949804 0.38 SERHL2
 serine hydrolase-like 2
 15
 0.95
chr7_855590_855863 0.38 SUN1
 Sad1 and UNC84 domain containing 1
 198
 0.94
chr5_42423499_42423764 0.38 GHR
 growth hormone receptor
 248
 0.96
chr10_124134109_124134260 0.37 PLEKHA1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
 28
 0.98
chr22_19420110_19420439 0.37 MRPL40
 mitochondrial ribosomal protein L40
 849
 0.35
chr7_76256241_76256478 0.37 POMZP3
 POM121 and ZP3 fusion
 198
 0.95
chr6_106960080_106960316 0.37 AIM1
 absent in melanoma 1
 468
 0.83
chr16_9057629_9057799 0.37 USP7
 ubiquitin specific peptidase 7 (herpes virus-associated)
 373
 0.88
chr9_37650643_37650806 0.36 FRMPD1
 FERM and PDZ domain containing 1
 273
 0.91
chr6_3751810_3752094 0.36 PXDC1
 PX domain containing 1
 308
 0.72
chr1_9600222_9600465 0.36 SLC25A33
 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
 802
 0.68
chr2_74780178_74780365 0.36 LOXL3
 lysyl oxidase-like 3
 60
 0.91
chr15_35838444_35838854 0.36 DPH6
 diphthamine biosynthesis 6
 256
 0.96
chr5_374047_374475 0.36 AHRR
 aryl-hydrocarbon receptor repressor
 30618
 0.14
chr16_2835054_2835205 0.35 PRSS33
 protease, serine, 33
 1477
 0.19
chr6_105584147_105584651 0.35 BVES
 blood vessel epicardial substance
 161
 0.57
chr2_24307248_24307399 0.35 TP53I3
 tumor protein p53 inducible protein 3
 127
 0.94
chr7_6010237_6010478 0.35 RSPH10B
 radial spoke head 10 homolog B (Chlamydomonas)
 43
 0.96
chr16_3201947_3202172 0.34 CASP16
 caspase 16, apoptosis-related cysteine peptidase (putative)
 7815
 0.08
chr12_64215712_64216078 0.34 TMEM5-AS1
 TMEM5 antisense RNA 1
 41
 0.97
chr11_33398418_33398586 0.34 ENSG00000223134
 .
 22491
 0.24
chr4_79697542_79697717 0.34 BMP2K
 BMP2 inducible kinase
 97
 0.87
chr15_72766829_72767031 0.34 ARIH1
 ariadne RBR E3 ubiquitin protein ligase 1
 56
 0.98
chr14_105219505_105220133 0.34 SIVA1
 SIVA1, apoptosis-inducing factor
 236
 0.89
chr7_6414358_6414509 0.34 RAC1
 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
 263
 0.91
chr7_75071593_75071917 0.33 POM121C
 POM121 transmembrane nucleoporin C
 238
 0.89
chr19_37808857_37809211 0.33 HKR1
 HKR1, GLI-Kruppel zinc finger family member
 93
 0.97
chr4_159092288_159092999 0.33 RP11-597D13.9
118
 0.94
chr11_63933058_63933366 0.33 MACROD1
 MACRO domain containing 1
 321
 0.79
chr15_37170307_37170458 0.33 ENSG00000212511
 .
 25541
 0.25
chr10_104678051_104678263 0.32 CNNM2
 cyclin M2
 43
 0.97
chr8_41167115_41167348 0.32 SFRP1
 secreted frizzled-related protein 1
 215
 0.93
chr11_777311_777493 0.32 PDDC1
 Parkinson disease 7 domain containing 1
 69
 0.63
chr15_48010424_48010678 0.32 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 107
 0.98
chr22_50453205_50453450 0.32 IL17REL
 interleukin 17 receptor E-like
 2239
 0.28
chr13_47216013_47216251 0.32 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 37839
 0.21
chr4_102267764_102268012 0.31 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
 65
 0.95
chr19_48996869_48997096 0.31 LMTK3
 lemur tyrosine kinase 3
 18079
 0.09
chr1_147072028_147072317 0.31 ACP6
 acid phosphatase 6, lysophosphatidic
 58944
 0.12
chr4_57975609_57976167 0.31 IGFBP7-AS1
 IGFBP7 antisense RNA 1
 40
 0.93
chr11_76380846_76381073 0.31 LRRC32
 leucine rich repeat containing 32
 85
 0.97
chr7_19155713_19156221 0.31 TWIST1
 twist family bHLH transcription factor 1
 1328
 0.36
chr10_8203120_8203271 0.30 GATA3
 GATA binding protein 3
 106426
 0.08
chr11_73053716_73053929 0.30 ENSG00000266866
 .
 14358
 0.13
chr7_23508285_23508467 0.30 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 1710
 0.33
chr14_90420619_90421056 0.30 EFCAB11
 EF-hand calcium binding domain 11
 30
 0.97
chr14_104314041_104314227 0.30 PPP1R13B
 protein phosphatase 1, regulatory subunit 13B
 207
 0.93
chr11_108092817_108093311 0.30 ATM
 ataxia telangiectasia mutated
 147
 0.7
chr6_35464523_35464729 0.30 TEAD3
 TEA domain family member 3
 101
 0.96
chr8_120685506_120685944 0.29 ENPP2
 ectonucleotide pyrophosphatase/phosphodiesterase 2
 32
 0.98
chr10_81002854_81003026 0.29 ZMIZ1
 zinc finger, MIZ-type containing 1
 63035
 0.13
chr11_46867490_46867892 0.29 CKAP5
 cytoskeleton associated protein 5
 89
 0.74
chr5_1004458_1005031 0.29 ENSG00000221244
 .
 442
 0.76
chr20_1373376_1373702 0.29 FKBP1A
 FK506 binding protein 1A, 12kDa
 67
 0.97
chr11_35440407_35440646 0.29 RP4-683L5.1
78
 0.51
chr5_122372476_122372950 0.29 PPIC
 peptidylprolyl isomerase C (cyclophilin C)
 277
 0.76
chr9_139701990_139702217 0.28 RABL6
 RAB, member RAS oncogene family-like 6
 271
 0.73
chr3_49507808_49508072 0.28 DAG1
 dystroglycan 1 (dystrophin-associated glycoprotein 1)
 188
 0.91
chr1_234614585_234614936 0.28 TARBP1
 TAR (HIV-1) RNA binding protein 1
 89
 0.98
chr10_128994049_128994367 0.28 FAM196A
 family with sequence similarity 196, member A
 214
 0.97
chr21_27011889_27012538 0.28 JAM2
 junctional adhesion molecule 2
 303
 0.91
chr10_69523317_69523672 0.28 ENSG00000212520
 .
 44766
 0.14
chr8_32405854_32406088 0.28 NRG1
 neuregulin 1
 166
 0.98
chr10_49514759_49514955 0.28 MAPK8
 mitogen-activated protein kinase 8
 124
 0.97
chr19_37288396_37289123 0.28 CTD-2162K18.5
294
 0.87
chr2_220435062_220435638 0.28 OBSL1
 obscurin-like 1
 613
 0.46
chr2_148602296_148602520 0.28 ACVR2A
 activin A receptor, type IIA
 223
 0.94
chr1_178694286_178694443 0.27 RALGPS2
 Ral GEF with PH domain and SH3 binding motif 2
 15
 0.96
chr7_1543718_1544009 0.27 INTS1
 integrator complex subunit 1
 140
 0.94
chr10_95256403_95256654 0.27 CEP55
 centrosomal protein 55kDa
 139
 0.96
chr5_5140719_5141010 0.27 ADAMTS16
 ADAM metallopeptidase with thrombospondin type 1 motif, 16
 421
 0.64
chr5_72416360_72416541 0.27 TMEM171
 transmembrane protein 171
 54
 0.97
chr15_68570443_68570594 0.27 FEM1B
 fem-1 homolog b (C. elegans)
 377
 0.86
chr12_40618491_40618684 0.27 LRRK2
 leucine-rich repeat kinase 2
 226
 0.89
chr7_72395715_72396075 0.27 RP11-313P13.5
232
 0.48
chr2_165811625_165811865 0.27 SLC38A11
 solute carrier family 38, member 11
 11
 0.98
chr15_42264476_42264768 0.27 EHD4
 EH-domain containing 4
 154
 0.71
chr5_10564701_10565028 0.27 ANKRD33B
 ankyrin repeat domain 33B
 284
 0.92
chr7_156685591_156685844 0.27 LMBR1
 limb development membrane protein 1
 36
 0.98
chr7_6388015_6388418 0.27 FAM220A
 family with sequence similarity 220, member A
 173
 0.95
chr3_133613529_133613925 0.27 RAB6B
 RAB6B, member RAS oncogene family
 164
 0.96
chr7_73721339_73721665 0.26 CLIP2
 CAP-GLY domain containing linker protein 2
 10375
 0.2
chr16_838918_839181 0.26 CHTF18
 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
 264
 0.68
chr10_96162839_96163095 0.26 TBC1D12
 TBC1 domain family, member 12
 706
 0.73
chr19_1016769_1016920 0.26 TMEM259
 transmembrane protein 259
 578
 0.5
chr10_122119_122586 0.26 TUBB8
 tubulin, beta 8 class VIII
 26848
 0.21
chr14_105331028_105331307 0.26 CEP170B
 centrosomal protein 170B
 450
 0.81
chr16_88923128_88923365 0.26 GALNS
 galactosamine (N-acetyl)-6-sulfate sulfatase
 39
 0.75
chr17_2241425_2241780 0.26 SGSM2
 small G protein signaling modulator 2
 686
 0.38
chr15_60883034_60883482 0.26 RORA
 RAR-related orphan receptor A
 1482
 0.47
chr8_56015390_56015541 0.26 XKR4
 XK, Kell blood group complex subunit-related family, member 4
 516
 0.84
chr8_146024621_146024801 0.26 ZNF517
 zinc finger protein 517
 409
 0.73
chr17_18761420_18761571 0.26 PRPSAP2
 phosphoribosyl pyrophosphate synthetase-associated protein 2
 1
 0.97
chr8_11421838_11422183 0.26 RP11-148O21.2
4481
 0.17
chrX_1572414_1572620 0.25 ASMTL
 acetylserotonin O-methyltransferase-like
 138
 0.96
chr19_46010705_46010952 0.25 VASP
 vasodilator-stimulated phosphoprotein
 79
 0.95
chr13_21278061_21278212 0.25 ENSG00000265710
 .
 294
 0.75
chr11_35547343_35547568 0.25 PAMR1
 peptidase domain containing associated with muscle regeneration 1
 124
 0.98
chr10_65225296_65225715 0.25 JMJD1C
 jumonji domain containing 1C
 136
 0.85
chr4_149363777_149364242 0.25 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 337
 0.94
chr17_54910275_54910729 0.25 C17orf67
 chromosome 17 open reading frame 67
 754
 0.45
chr8_6263381_6263962 0.24 RP11-115C21.2
392
 0.53
chrY_1522413_1522621 0.24 NA
 NA
 > 106
 NA
chr13_27609001_27609357 0.24 USP12-AS1
 USP12 antisense RNA 1
 127813
 0.05
chr1_61508850_61509074 0.24 NFIA
 nuclear factor I/A
 10540
 0.24
chr15_75959711_75959976 0.24 CTD-2026K11.1
8725
 0.09
chr6_31367554_31367760 0.23 HCP5
 HLA complex P5 (non-protein coding)
 822
 0.41
chr4_141074061_141074265 0.23 MAML3
 mastermind-like 3 (Drosophila)
 40
 0.98
chr15_75871309_75871637 0.23 PTPN9
 protein tyrosine phosphatase, non-receptor type 9
 157
 0.94
chr17_73106469_73106784 0.23 ARMC7
 armadillo repeat containing 7
 350
 0.74
chr2_37551185_37551584 0.23 PRKD3
 protein kinase D3
 567
 0.73
chr11_209086_209652 0.23 RIC8A
 RIC8 guanine nucleotide exchange factor A
 261
 0.8
chr22_43538820_43539142 0.23 MCAT
 malonyl CoA:ACP acyltransferase (mitochondrial)
 11
 0.97
chr12_54354872_54355023 0.23 HOTAIR
 HOX transcript antisense RNA
 5467
 0.07
chr18_25756897_25757048 0.23 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 438
 0.91
chr12_22487067_22487257 0.23 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 31
 0.99
chr1_228464183_228464334 0.23 RP5-1139B12.3
491
 0.48
chr17_80656941_80657233 0.23 RAB40B
 RAB40B, member RAS oncogene family
 483
 0.69
chr5_135170799_135170980 0.23 SLC25A48
 solute carrier family 25, member 48
 473
 0.79
chr18_72916975_72917266 0.23 ZADH2
 zinc binding alcohol dehydrogenase domain containing 2
 348
 0.91
chr8_41510934_41511242 0.23 NKX6-3
 NK6 homeobox 3
 2233
 0.21
chr4_56212888_56213283 0.23 SRD5A3
 steroid 5 alpha-reductase 3
 506
 0.78
chr16_87418056_87418265 0.23 FBXO31
 F-box protein 31
 797
 0.5
chr7_21467158_21467466 0.23 SP4
 Sp4 transcription factor
 340
 0.88
chr13_30423998_30424231 0.23 UBL3
 ubiquitin-like 3
 707
 0.8
chr1_110753009_110753414 0.23 KCNC4-AS1
 KCNC4 antisense RNA 1 (head to head)
 602
 0.5
chr8_144329132_144329362 0.22 ZFP41
33
 0.96
chr22_37816262_37816667 0.22 RP1-63G5.5
7016
 0.15
chr12_53773947_53774144 0.22 SP1
 Sp1 transcription factor
 67
 0.96
chr10_118897247_118897476 0.22 VAX1
 ventral anterior homeobox 1
 206
 0.94
chr12_57623777_57624582 0.22 SHMT2
 serine hydroxymethyltransferase 2 (mitochondrial)
 28
 0.95
chr16_89786763_89786992 0.22 ZNF276
 zinc finger protein 276
 69
 0.87
chr18_75721_75894 0.22 RP11-683L23.1
 Tubulin beta-8 chain-like protein LOC260334
 25567
 0.21
chr1_169075995_169076869 0.22 ATP1B1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 713
 0.64
chr14_103988937_103989088 0.22 CKB
 creatine kinase, brain
 21
 0.95
chr14_37641071_37641282 0.22 SLC25A21-AS1
 SLC25A21 antisense RNA 1
 83
 0.86
chr15_89347186_89347337 0.22 ACAN
 aggrecan
 271
 0.94
chr8_97157411_97157669 0.22 GDF6
 growth differentiation factor 6
 15480
 0.24
chr7_76179340_76179569 0.22 AC004980.7
519
 0.76
chr11_30607186_30607487 0.22 MPPED2
 metallophosphoesterase domain containing 2
 492
 0.79
chrX_132549723_132550137 0.22 GPC4
 glypican 4
 412
 0.9
chr7_154794514_154794665 0.22 PAXIP1
 PAX interacting (with transcription-activation domain) protein 1
 32
 0.98
chr15_74657875_74658107 0.22 CTD-2311M21.3
215
 0.75
chr11_101981627_101982145 0.22 YAP1
 Yes-associated protein 1
 306
 0.88
chr13_95359649_95360125 0.22 SOX21
 SRY (sex determining region Y)-box 21
 4502
 0.23
chr14_30396439_30396658 0.22 PRKD1
 protein kinase D1
 300
 0.93
chr7_117512754_117513170 0.22 CTTNBP2
 cortactin binding protein 2
 599
 0.85
chr4_128702866_128703017 0.22 HSPA4L
 heat shock 70kDa protein 4-like
 35
 0.98
chr2_64371263_64371562 0.21 PELI1
 pellino E3 ubiquitin protein ligase 1
 176
 0.92
chr12_26348638_26349346 0.21 SSPN
 sarcospan
 386
 0.88
chr2_201577707_201577963 0.21 AOX1
 aldehyde oxidase 1
 50205
 0.11
chr16_49315968_49316184 0.21 CBLN1
 cerebellin 1 precursor
 334
 0.91
chrX_56756434_56756710 0.21 ENSG00000204272
 .
 880
 0.75
chr17_21477931_21478085 0.21 ENSG00000216100
 .
 3076
 0.28
chr20_33413142_33413293 0.21 NCOA6
 nuclear receptor coactivator 6
 235
 0.93
chr2_119981485_119981702 0.21 STEAP3
 STEAP family member 3, metalloreductase
 164
 0.96
chr19_3585741_3585963 0.21 GIPC3
 GIPC PDZ domain containing family, member 3
 301
 0.79
chr17_5404167_5404422 0.21 ENSG00000253071
 .
 13296
 0.12
chr9_131937344_131937495 0.21 RP11-247A12.8
667
 0.53
chr9_38526880_38527031 0.21 SNX18P3
 sorting nexin 18 pseudogene 3
 41253
 0.16
chrX_71997022_71997182 0.21 DMRTC1B
 DMRT-like family C1B
 130
 0.74
chr7_6793577_6794001 0.21 RSPH10B2
 radial spoke head 10 homolog B2 (Chlamydomonas)
 41
 0.97
chr10_75117873_75118271 0.21 TTC18
 tetratricopeptide repeat domain 18
 464
 0.72
chr3_52312831_52313120 0.21 WDR82
 WD repeat domain 82
 316
 0.77
chr6_106577027_106577713 0.21 RP1-134E15.3
29355
 0.19
chr14_76044289_76044527 0.21 FLVCR2
 feline leukemia virus subgroup C cellular receptor family, member 2
 552
 0.67
chr15_83952425_83952671 0.21 BNC1
 basonuclin 1
 477
 0.85
chr21_35446318_35446469 0.21 SLC5A3
 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
 523
 0.49
chr5_17217814_17217965 0.21 BASP1
 brain abundant, membrane attached signal protein 1
 220
 0.83
chr16_49562822_49562973 0.21 ZNF423
 zinc finger protein 423
 111866
 0.07
chr8_1771644_1772131 0.21 ARHGEF10
 Rho guanine nucleotide exchange factor (GEF) 10
 255
 0.93

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.4 GO:0046449 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.5 GO:0001553 luteinization(GO:0001553)
0.1 0.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.4 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.2 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0030952 establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.1 0.3 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.3 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.5 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.2 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.3 GO:0022417 protein maturation by protein folding(GO:0022417)
0.1 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.3 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.2 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.1 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.2 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.2 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.3 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.2 GO:0007100 mitotic centrosome separation(GO:0007100)
0.1 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0045112 integrin biosynthetic process(GO:0045112)
0.0 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.2 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:1904376 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.0 GO:0048895 sensory system development(GO:0048880) lateral line nerve development(GO:0048892) lateral line nerve glial cell differentiation(GO:0048895) lateral line system development(GO:0048925) lateral line nerve glial cell development(GO:0048937) iridophore differentiation(GO:0050935)
0.0 0.2 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.0 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.1 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.1 GO:0034227 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.1 GO:0031223 auditory behavior(GO:0031223)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0061047 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0006853 carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0 0.1 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0030157 pancreatic juice secretion(GO:0030157)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0051307 resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.0 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0009129 pyrimidine nucleoside monophosphate metabolic process(GO:0009129)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.5 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.0 0.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.1 GO:0001967 suckling behavior(GO:0001967)
0.0 0.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.2 GO:0046132 pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0 0.2 GO:0008088 axo-dendritic transport(GO:0008088)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.0 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.3 GO:0033280 response to vitamin D(GO:0033280)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.2 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.0 GO:0002220 innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0 0.1 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.2 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0051383 kinetochore organization(GO:0051383)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.3 GO:0006739 NADP metabolic process(GO:0006739)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0060479 lung cell differentiation(GO:0060479)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.0 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.1 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.0 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 1.1 GO:0009063 cellular amino acid catabolic process(GO:0009063)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0009268 response to pH(GO:0009268)
0.0 0.0 GO:0072202 cell differentiation involved in metanephros development(GO:0072202)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0072077 renal vesicle morphogenesis(GO:0072077)
0.0 0.1 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.3 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.1 GO:0014909 smooth muscle cell migration(GO:0014909)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0019049 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway(GO:0031664)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0 0.0 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.0 GO:0046325 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0060768 epithelial cell proliferation involved in prostate gland development(GO:0060767) regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.0 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0006563 L-serine metabolic process(GO:0006563)
0.0 0.0 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.4 GO:0071773 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.1 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0051322 anaphase(GO:0051322)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0052572 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.5 GO:0034339 obsolete regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor(GO:0034339)
0.0 0.2 GO:0060606 tube closure(GO:0060606)
0.0 0.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.0 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.1 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0046083 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720) negative regulation of tumor necrosis factor superfamily cytokine production(GO:1903556)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.1 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 0.8 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0042587 glycogen granule(GO:0042587)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.0 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.2 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.0 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0097610 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0005925 focal adhesion(GO:0005925)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016212 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.1 0.4 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.5 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0034711 inhibin binding(GO:0034711)
0.1 0.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 0.4 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.2 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1 0.5 GO:0070410 co-SMAD binding(GO:0070410)
0.1 0.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0005521 lamin binding(GO:0005521)
0.1 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0005522 profilin binding(GO:0005522)
0.1 0.3 GO:0016417 S-acyltransferase activity(GO:0016417)
0.1 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.1 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.2 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.2 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.4 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0016679 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0016803 ether hydrolase activity(GO:0016803)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.2 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.3 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0001948 glycoprotein binding(GO:0001948)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.0 GO:0046980 tapasin binding(GO:0046980)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.3 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.0 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.0 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.2 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.0 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.0 0.0 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.3 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.5 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.4 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.0 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.0 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.0 REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES Genes involved in Transmembrane transport of small molecules
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK