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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HINFP1

Z-value: 0.56

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Transcription factors associated with HINFP1

Gene Symbol Gene ID Gene Info

Activity of the HINFP1 motif across conditions

Conditions sorted by the z-value of the HINFP1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_30454378_30455881 0.45 LBH
 limb bud and heart development
 83
 0.98
chr20_3994903_3996170 0.42 RNF24
 ring finger protein 24
 500
 0.83
chr17_57408824_57410302 0.40 YPEL2
 yippee-like 2 (Drosophila)
 500
 0.78
chr1_62784626_62784933 0.38 KANK4
 KN motif and ankyrin repeat domains 4
 193
 0.95
chr2_96809842_96811219 0.38 DUSP2
 dual specificity phosphatase 2
 649
 0.65
chr3_96531977_96533205 0.34 EPHA6
 EPH receptor A6
 834
 0.76
chr7_26415747_26416790 0.34 AC004540.4
53
 0.98
chr1_169454193_169456202 0.32 SLC19A2
 solute carrier family 19 (thiamine transporter), member 2
 28
 0.98
chr16_67197260_67198336 0.31 HSF4
 heat shock transcription factor 4
 510
 0.52
chr1_231297648_231298418 0.26 TRIM67
 tripartite motif containing 67
 175
 0.95
chr20_708643_709189 0.24 SLC52A3
 solute carrier family 52 (riboflavin transporter), member 3
 40215
 0.13
chr19_2251617_2252237 0.23 ENSG00000267021
 .
 1289
 0.21
chr1_11724348_11725085 0.21 FBXO6
 F-box protein 6
 535
 0.67
chr18_47017567_47018883 0.21 RPL17
 ribosomal protein L17
 15
 0.51
chr20_35974122_35974616 0.20 SRC
 v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
 188
 0.96
chr17_79875057_79876036 0.20 SIRT7
 sirtuin 7
 524
 0.46
chr10_62492315_62493446 0.20 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 368
 0.92
chr11_120894558_120895785 0.19 TBCEL
 tubulin folding cofactor E-like
 341
 0.93
chr13_22032188_22033345 0.18 ZDHHC20
 zinc finger, DHHC-type containing 20
 648
 0.76
chr22_24989005_24989426 0.18 FAM211B
 family with sequence similarity 211, member B
 185
 0.9
chr3_196695819_196696888 0.17 PIGZ
 phosphatidylinositol glycan anchor biosynthesis, class Z
 611
 0.66
chr8_69242814_69243988 0.17 C8orf34
 chromosome 8 open reading frame 34
 56
 0.82
chr7_101460813_101461304 0.17 CUX1
 cut-like homeobox 1
 138
 0.97
chr6_163833862_163834944 0.17 QKI
 QKI, KH domain containing, RNA binding
 1272
 0.63
chr13_20766378_20767168 0.16 GJB2
 gap junction protein, beta 2, 26kDa
 264
 0.91
chr12_90101448_90102652 0.15 ATP2B1
 ATPase, Ca++ transporting, plasma membrane 1
 558
 0.78
chr3_160822448_160823114 0.15 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
 43
 0.67
chr4_187025490_187026623 0.15 FAM149A
 family with sequence similarity 149, member A
 175
 0.94
chr18_12308279_12308732 0.15 TUBB6
 tubulin, beta 6 class V
 243
 0.92
chr1_935525_936213 0.15 HES4
 hes family bHLH transcription factor 4
 317
 0.77
chr1_236958581_236959780 0.14 MTR
 5-methyltetrahydrofolate-homocysteine methyltransferase
 198
 0.96
chr10_123733982_123734880 0.14 NSMCE4A
 non-SMC element 4 homolog A (S. cerevisiae)
 158
 0.96
chr2_71693301_71694189 0.13 DYSF
 dysferlin
 87
 0.98
chr9_86595749_86596582 0.13 RMI1
 RecQ mediated genome instability 1
 452
 0.51
chr16_84733607_84734797 0.13 USP10
 ubiquitin specific peptidase 10
 556
 0.79
chr12_95942120_95942537 0.13 USP44
 ubiquitin specific peptidase 44
 246
 0.94
chr9_131418722_131419532 0.13 WDR34
 WD repeat domain 34
 61
 0.96
chr7_111201649_111202512 0.13 IMMP2L
 IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
 100
 0.98
chr19_13056666_13057332 0.13 RAD23A
 RAD23 homolog A (S. cerevisiae)
 293
 0.71
chr20_1875023_1875335 0.12 SIRPA
 signal-regulatory protein alpha
 25
 0.98
chrX_70150677_70150828 0.12 SLC7A3
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
 194
 0.95
chr6_100061682_100062402 0.12 PRDM13
 PR domain containing 13
 7436
 0.19
chr10_50606076_50606780 0.11 DRGX
 dorsal root ganglia homeobox
 2931
 0.27
chr6_1605443_1605730 0.11 FOXC1
 forkhead box C1
 5095
 0.33
chr9_37034211_37034515 0.11 PAX5
 paired box 5
 260
 0.93
chr13_67804057_67805835 0.11 PCDH9
 protocadherin 9
 478
 0.9
chr1_110753494_110754182 0.11 KCNC4
 potassium voltage-gated channel, Shaw-related subfamily, member 4
 257
 0.84
chr16_30216869_30217924 0.11 RP11-347C12.3
 Uncharacterized protein
 31
 0.94
chr20_57465496_57466112 0.10 GNAS
 GNAS complex locus
 553
 0.66
chr18_3262315_3263346 0.10 MYL12B
 myosin, light chain 12B, regulatory
 124
 0.92
chr2_129079627_129080191 0.10 HS6ST1
 heparan sulfate 6-O-sulfotransferase 1
 3758
 0.29
chr10_94822298_94822949 0.10 CYP26C1
 cytochrome P450, family 26, subfamily C, polypeptide 1
 1602
 0.34
chr7_149156320_149157211 0.10 ZNF777
 zinc finger protein 777
 1449
 0.45
chr16_718193_719247 0.09 RHOT2
 ras homolog family member T2
 511
 0.45
chr5_131745958_131747299 0.09 C5orf56
 chromosome 5 open reading frame 56
 45
 0.96
chr3_12910219_12910517 0.09 AC034198.7
18210
 0.14
chr8_37620085_37620952 0.08 PROSC
 proline synthetase co-transcribed homolog (bacterial)
 400
 0.79
chr6_108497513_108497836 0.07 NR2E1
 nuclear receptor subfamily 2, group E, member 1
 7707
 0.18
chr2_71453255_71454205 0.07 PAIP2B
 poly(A) binding protein interacting protein 2B
 483
 0.83
chr6_168720263_168720414 0.07 DACT2
 dishevelled-binding antagonist of beta-catenin 2
 52
 0.98
chr17_27892819_27893926 0.07 ABHD15
 abhydrolase domain containing 15
 783
 0.31
chr7_139875207_139876022 0.07 KDM7A
 lysine (K)-specific demethylase 7A
 1127
 0.39
chr17_40202025_40202687 0.07 CTD-2132N18.2
7221
 0.11
chr7_100081068_100081412 0.07 ENSG00000266372
 .
 226
 0.55
chr7_92218956_92219793 0.07 FAM133B
 family with sequence similarity 133, member B
 10
 0.98
chr6_30457259_30457905 0.07 HLA-E
 major histocompatibility complex, class I, E
 338
 0.84
chr6_45631346_45631892 0.06 ENSG00000252738
 .
 17778
 0.29
chr10_112403107_112403970 0.06 RBM20
 RNA binding motif protein 20
 617
 0.55
chr20_3827532_3828225 0.06 MAVS
 mitochondrial antiviral signaling protein
 388
 0.8
chr1_27687344_27687533 0.06 MAP3K6
 mitogen-activated protein kinase kinase kinase 6
 3004
 0.16
chr10_21823798_21823949 0.06 MLLT10
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
 195
 0.92
chr19_4374282_4374693 0.06 SH3GL1
 SH3-domain GRB2-like 1
 5802
 0.08
chr7_132260669_132261651 0.05 PLXNA4
 plexin A4
 69
 0.98
chr4_186130212_186131033 0.05 KIAA1430
 KIAA1430
 36
 0.92
chr22_20306851_20307537 0.05 DGCR6L
 DiGeorge syndrome critical region gene 6-like
 338
 0.74
chr14_56585152_56585591 0.05 PELI2
 pellino E3 ubiquitin protein ligase family member 2
 278
 0.94
chr8_143533593_143534231 0.05 BAI1
 brain-specific angiogenesis inhibitor 1
 3121
 0.27
chr2_178128520_178129352 0.05 AC079305.10
151
 0.76
chr18_29264680_29264911 0.05 B4GALT6
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
 109
 0.91
chr15_66585571_66586039 0.05 DIS3L
 DIS3 mitotic control homolog (S. cerevisiae)-like
 80
 0.53
chr11_70962576_70962972 0.05 SHANK2
 SH3 and multiple ankyrin repeat domains 2
 849
 0.72
chr4_87812935_87814058 0.05 C4orf36
 chromosome 4 open reading frame 36
 52
 0.98
chr6_29894399_29894823 0.05 HLA-A
 major histocompatibility complex, class I, A
 14426
 0.18
chr6_11043780_11044551 0.05 ELOVL2-AS1
 ELOVL2 antisense RNA 1
 172
 0.73
chr1_156829720_156830506 0.05 NTRK1
 neurotrophic tyrosine kinase, receptor, type 1
 494
 0.64
chr17_11144173_11144324 0.05 SHISA6
 shisa family member 6
 332
 0.91
chr1_233463556_233464041 0.05 MLK4
 Mitogen-activated protein kinase kinase kinase MLK4
 284
 0.94
chr18_11981851_11982483 0.04 IMPA2
 inositol(myo)-1(or 4)-monophosphatase 2
 498
 0.77
chrY_21154472_21155007 0.04 ENSG00000252766
 .
 26234
 0.25
chr2_136289143_136290038 0.04 R3HDM1
 R3H domain containing 1
 503
 0.62
chr20_52209104_52210193 0.04 ZNF217
 zinc finger protein 217
 730
 0.68
chr17_77817761_77818338 0.04 CBX4
 chromobox homolog 4
 4821
 0.18
chr17_16487582_16488116 0.04 ZNF287
 zinc finger protein 287
 15329
 0.16
chr1_207082522_207083417 0.04 IL24
 interleukin 24
 11791
 0.14
chr6_84569350_84570131 0.03 CYB5R4
 cytochrome b5 reductase 4
 365
 0.9
chr19_50354346_50354967 0.03 PTOV1
 prostate tumor overexpressed 1
 174
 0.58
chr17_40829888_40830324 0.03 PLEKHH3
 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
 1058
 0.27
chr1_29448339_29449190 0.03 TMEM200B
 transmembrane protein 200B
 249
 0.93
chr11_450302_450786 0.03 PTDSS2
 phosphatidylserine synthase 2
 264
 0.82
chr7_107220684_107221346 0.03 BCAP29
 B-cell receptor-associated protein 29
 102
 0.86
chr7_96635926_96636202 0.03 DLX6
 distal-less homeobox 6
 673
 0.48
chr3_14644257_14644427 0.03 AC090952.5
46597
 0.13
chr4_109093413_109093782 0.03 ENSG00000232021
 .
 258
 0.93
chr16_58059170_58059939 0.03 MMP15
 matrix metallopeptidase 15 (membrane-inserted)
 84
 0.96
chr2_33171552_33172146 0.03 LTBP1
 latent transforming growth factor beta binding protein 1
 190
 0.93
chr3_182896879_182897541 0.03 LAMP3
 lysosomal-associated membrane protein 3
 15583
 0.21
chrX_49033425_49033576 0.03 PLP2
 proteolipid protein 2 (colonic epithelium-enriched)
 5227
 0.09
chr18_32956679_32957498 0.03 ZNF396
 zinc finger protein 396
 186
 0.96
chr2_232526625_232527001 0.03 ENSG00000239202
 .
 15829
 0.16
chr20_32077934_32078551 0.02 CBFA2T2
 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
 319
 0.89
chr2_234263629_234264304 0.02 DGKD
 diacylglycerol kinase, delta 130kDa
 812
 0.51
chr12_58129779_58130334 0.02 AGAP2
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
 1563
 0.16
chr6_159360525_159360963 0.02 ENSG00000223191
 .
 13141
 0.19
chr10_8091983_8093018 0.02 GATA3
 GATA binding protein 3
 4156
 0.36
chr5_159546809_159547203 0.02 PWWP2A
 PWWP domain containing 2A
 576
 0.75
chr3_52016673_52017699 0.02 ABHD14B
 abhydrolase domain containing 14B
 239
 0.49
chr17_17603690_17604249 0.02 RAI1
 retinoic acid induced 1
 18160
 0.17
chr5_174871055_174871780 0.02 DRD1
 dopamine receptor D1
 206
 0.95
chr5_92906290_92906587 0.02 ENSG00000237187
 .
 61
 0.98
chr12_133532729_133533161 0.02 ZNF605
 zinc finger protein 605
 53
 0.49
chr1_10458416_10458839 0.02 PGD
 phosphogluconate dehydrogenase
 22
 0.96
chr3_139654401_139654885 0.02 CLSTN2
 calsyntenin 2
 616
 0.84
chr11_805194_805716 0.02 PIDD
 p53-induced death domain protein
 210
 0.8
chr19_12780320_12781072 0.02 WDR83
 WD repeat domain 83
 179
 0.62
chr5_139028499_139029117 0.02 CXXC5
 CXXC finger protein 5
 290
 0.92
chr2_237087502_237088103 0.02 GBX2
 gastrulation brain homeobox 2
 10790
 0.15
chr9_139439215_139440028 0.02 NOTCH1
 notch 1
 693
 0.35
chr13_21635697_21635989 0.02 LATS2
 large tumor suppressor kinase 2
 157
 0.95
chr12_109747933_109748276 0.02 FOXN4
 forkhead box N4
 1079
 0.55
chr7_32535106_32535501 0.02 AVL9
 AVL9 homolog (S. cerevisiase)
 19
 0.88
chr1_224622519_224623397 0.02 WDR26
 WD repeat domain 26
 957
 0.59
chr12_27932510_27932994 0.02 KLHL42
 kelch-like family member 42
 201
 0.87
chr6_24720330_24720995 0.02 C6orf62
 chromosome 6 open reading frame 62
 42
 0.97
chr13_28528843_28528994 0.02 ATP5EP2
 ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit pseudogene 2
 9575
 0.14
chr20_34189521_34189992 0.02 SPAG4
 sperm associated antigen 4
 14058
 0.11
chr7_75911448_75912023 0.01 SRRM3
 serine/arginine repetitive matrix 3
 197
 0.93
chr14_45366753_45367297 0.01 C14orf28
 chromosome 14 open reading frame 28
 487
 0.59
chr1_148176495_148177244 0.01 PPIAL4D
 peptidylprolyl isomerase A (cyclophilin A)-like 4D
 25667
 0.21
chr5_6714492_6714756 0.01 PAPD7
 PAP associated domain containing 7
 94
 0.98
chr11_67275372_67275646 0.01 CDK2AP2
 cyclin-dependent kinase 2 associated protein 2
 53
 0.93
chr12_19283254_19284293 0.01 PLEKHA5
 pleckstrin homology domain containing, family A member 5
 1043
 0.58
chr5_129239637_129240094 0.01 CHSY3
 chondroitin sulfate synthase 3
 300
 0.88
chr11_64901308_64901962 0.01 SYVN1
 synovial apoptosis inhibitor 1, synoviolin
 265
 0.76
chr16_75033808_75034560 0.01 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 941
 0.6
chr7_27179265_27179416 0.01 HOXA3
 homeobox A3
 485
 0.41
chrX_129299242_129299778 0.01 AIFM1
 apoptosis-inducing factor, mitochondrion-associated, 1
 128
 0.96
chr19_6767133_6767491 0.01 SH2D3A
 SH2 domain containing 3A
 134
 0.93
chr6_18277489_18278102 0.01 ENSG00000199715
 .
 4298
 0.21
chr12_6833255_6834039 0.01 COPS7A
 COP9 signalosome subunit 7A
 175
 0.85
chr4_190936109_190936296 0.01 ENSG00000199572
 .
 91
 0.95
chr1_24829331_24829634 0.01 RCAN3
 RCAN family member 3
 95
 0.97
chr7_157072082_157072490 0.01 ENSG00000266453
 .
 26201
 0.21
chr17_46674549_46675551 0.01 HOXB-AS3
 HOXB cluster antisense RNA 3
 1249
 0.2
chr2_220416827_220417484 0.01 ENSG00000265252
 .
 3286
 0.09
chr17_56234195_56234709 0.01 OR4D1
 olfactory receptor, family 4, subfamily D, member 1
 1958
 0.26
chr10_119135118_119135768 0.01 PDZD8
 PDZ domain containing 8
 465
 0.84
chr11_68228271_68228585 0.01 PPP6R3
 protein phosphatase 6, regulatory subunit 3
 147
 0.96
chr17_12920409_12921278 0.01 ELAC2
 elaC ribonuclease Z 2
 64
 0.97
chr11_119454980_119455308 0.01 RP11-196E1.3
23991
 0.19
chr17_38296734_38297043 0.01 CASC3
 cancer susceptibility candidate 3
 207
 0.9
chr5_5421590_5422497 0.01 KIAA0947
 KIAA0947
 764
 0.8
chr3_141120790_141121159 0.01 ZBTB38
 zinc finger and BTB domain containing 38
 217
 0.95
chr1_165796835_165797193 0.00 TMCO1
 transmembrane and coiled-coil domains 1
 22
 0.51
chr19_4304444_4304595 0.00 FSD1
 fibronectin type III and SPRY domain containing 1
 78
 0.93
chr7_74306205_74306628 0.00 STAG3L2
 stromal antigen 3-like 2 (pseudogene)
 259
 0.91
chr19_16999844_17000017 0.00 F2RL3
 coagulation factor II (thrombin) receptor-like 3
 71
 0.95
chr7_26192093_26192429 0.00 NFE2L3
 nuclear factor, erythroid 2-like 3
 401
 0.85
chr3_50358230_50358862 0.00 HYAL2
 hyaluronoglucosaminidase 2
 34
 0.93
chr16_77224093_77224603 0.00 MON1B
 MON1 secretory trafficking family member B
 384
 0.86
chr6_157801166_157801713 0.00 ZDHHC14
 zinc finger, DHHC-type containing 14
 726
 0.76
chr16_30662970_30663539 0.00 PRR14
 proline rich 14
 743
 0.43
chr8_56987192_56987600 0.00 CTA-397H3.3
245
 0.54
chr12_120632090_120632489 0.00 GCN1L1
 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
 224
 0.88
chr7_89783488_89783754 0.00 STEAP1
 six transmembrane epithelial antigen of the prostate 1
 68
 0.97
chr22_18893815_18894459 0.00 DGCR6
 DiGeorge syndrome critical region gene 6
 271
 0.91
chr1_43232974_43233556 0.00 C1orf50
 chromosome 1 open reading frame 50
 288
 0.65
chr14_23526484_23526858 0.00 CDH24
 cadherin 24, type 2
 76
 0.93

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HINFP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.0 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.0 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions