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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HMGA2

Z-value: 0.56

Motif logo

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Transcription factors associated with HMGA2

Gene Symbol Gene ID Gene Info
HMGA2
ENSG00000149948.9 high mobility group AT-hook 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_66159147_66159298HMGA2586890.1336340.818.2e-03Click!
chr12_66198631_66198915HMGA2191380.2139910.627.4e-02Click!
chr12_66219476_66219782HMGA27260.7096280.627.7e-02Click!
chr12_66198930_66199081HMGA2189060.2143280.627.8e-02Click!
chr12_66048530_66048681HMGA21693060.0331350.627.8e-02Click!

Activity of the HMGA2 motif across conditions

Conditions sorted by the z-value of the HMGA2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr20_52271481_52272252 0.31 ENSG00000238468
 .
 13431
 0.22
chr6_17986477_17986974 0.24 KIF13A
 kinesin family member 13A
 969
 0.69
chr8_53851583_53851734 0.21 NPBWR1
 neuropeptides B/W receptor 1
 667
 0.79
chr2_147579520_147579813 0.21 ENSG00000238860
 .
 501873
 0.0
chr2_26100038_26101197 0.21 ASXL2
 additional sex combs like 2 (Drosophila)
 718
 0.76
chr4_15908125_15908316 0.20 FGFBP1
 fibroblast growth factor binding protein 1
 31751
 0.17
chr5_171380881_171381289 0.19 FBXW11
 F-box and WD repeat domain containing 11
 23675
 0.23
chr18_53255518_53256419 0.18 TCF4
 transcription factor 4
 108
 0.98
chr7_32929941_32930760 0.18 KBTBD2
 kelch repeat and BTB (POZ) domain containing 2
 415
 0.87
chr17_79371776_79372295 0.18 RP11-1055B8.7
 BAH and coiled-coil domain-containing protein 1
 1505
 0.24
chr4_95469395_95469810 0.17 PDLIM5
 PDZ and LIM domain 5
 24726
 0.27
chr3_153037931_153038307 0.17 ENSG00000265813
 .
 120313
 0.06
chr5_139968434_139968585 0.17 ENSG00000200235
 .
 9257
 0.08
chr10_114714851_114715858 0.16 RP11-57H14.2
3720
 0.26
chr2_188418561_188419245 0.16 AC007319.1
27
 0.69
chr12_22005080_22005298 0.16 RP11-729I10.2
25045
 0.19
chr20_14310710_14310861 0.16 FLRT3
 fibronectin leucine rich transmembrane protein 3
 7469
 0.25
chr3_27765284_27765702 0.15 EOMES
 eomesodermin
 1287
 0.62
chr18_42288728_42289100 0.15 SETBP1
 SET binding protein 1
 11785
 0.32
chr9_111773050_111773591 0.15 CTNNAL1
 catenin (cadherin-associated protein), alpha-like 1
 2459
 0.23
chr3_174819626_174819777 0.15 ENSG00000230292
 .
 13331
 0.3
chr5_58571069_58571855 0.15 PDE4D
 phosphodiesterase 4D, cAMP-specific
 483
 0.9
chr19_6076628_6076815 0.15 CTC-232P5.3
8757
 0.15
chr4_32149379_32149669 0.15 NA
 NA
 > 106
 NA
chr2_198146440_198146591 0.15 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 20728
 0.16
chr10_33552568_33552719 0.15 NRP1
 neuropilin 1
 11
 0.98
chr7_117919021_117919172 0.15 ANKRD7
 ankyrin repeat domain 7
 54145
 0.17
chr5_34609228_34609529 0.15 RAI14
 retinoic acid induced 14
 46964
 0.16
chr3_99544366_99544517 0.15 CMSS1
 cms1 ribosomal small subunit homolog (yeast)
 7760
 0.24
chr2_40049399_40049550 0.15 SLC8A1-AS1
 SLC8A1 antisense RNA 1
 35881
 0.19
chr2_238732566_238732717 0.15 RBM44
 RNA binding motif protein 44
 24820
 0.17
chr6_98074983_98075489 0.15 MMS22L
 MMS22-like, DNA repair protein
 344184
 0.01
chr5_153424892_153425043 0.15 MFAP3
 microfibrillar-associated protein 3
 6408
 0.22
chr11_37276640_37276791 0.14 ENSG00000251838
 .
 447055
 0.01
chr4_157996824_157996975 0.14 GLRB
 glycine receptor, beta
 310
 0.91
chr10_98433378_98434045 0.14 PIK3AP1
 phosphoinositide-3-kinase adaptor protein 1
 4343
 0.25
chr6_84139529_84139855 0.14 ME1
 malic enzyme 1, NADP(+)-dependent, cytosolic
 1072
 0.62
chr2_106886104_106886958 0.14 UXS1
 UDP-glucuronate decarboxylase 1
 75736
 0.1
chr4_139162325_139164249 0.14 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 216
 0.97
chr16_83860165_83860316 0.14 HSBP1
 heat shock factor binding protein 1
 18646
 0.15
chr10_5723817_5723968 0.14 FAM208B
 family with sequence similarity 208, member B
 2909
 0.23
chr9_128511491_128511642 0.14 PBX3
 pre-B-cell leukemia homeobox 3
 1088
 0.62
chr10_17241830_17242242 0.14 TRDMT1
 tRNA aspartic acid methyltransferase 1
 1543
 0.37
chr14_51421850_51422001 0.14 PYGL
 phosphorylase, glycogen, liver
 10471
 0.2
chr1_206685685_206685836 0.14 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 4881
 0.16
chr12_31470154_31471349 0.14 FAM60A
 family with sequence similarity 60, member A
 6345
 0.16
chr6_27515697_27516098 0.14 ENSG00000206671
 .
 48294
 0.13
chr6_143140776_143141820 0.14 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 16886
 0.26
chr12_29716327_29716478 0.13 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
 40755
 0.16
chr4_175135836_175136127 0.13 FBXO8
 F-box protein 8
 68833
 0.12
chr4_157729119_157729270 0.13 RP11-154F14.2
33317
 0.19
chr13_40081557_40081708 0.13 ENSG00000238408
 .
 60279
 0.13
chr11_22380798_22380949 0.13 CTD-2140G10.4
2967
 0.27
chr8_13909602_13909753 0.13 RP11-3G21.1
109129
 0.07
chr9_109668731_109668882 0.13 RP11-508N12.4
 Uncharacterized protein
 16824
 0.21
chr5_64543321_64543472 0.13 ENSG00000207439
 .
 124200
 0.06
chr9_95590209_95590360 0.13 ENSG00000252772
 .
 7025
 0.17
chr2_230148069_230148220 0.13 PID1
 phosphotyrosine interaction domain containing 1
 12143
 0.27
chr1_209528208_209528359 0.13 ENSG00000230937
 .
 77195
 0.12
chrX_2670582_2670733 0.13 XG
 Xg blood group
 471
 0.83
chr10_75938020_75938413 0.13 ADK
 adenosine kinase
 1695
 0.42
chr3_32282148_32282299 0.13 CMTM8
 CKLF-like MARVEL transmembrane domain containing 8
 2052
 0.26
chr3_28025237_28025388 0.13 CMC1
 C-x(9)-C motif containing 1
 257774
 0.02
chr1_207489819_207490027 0.13 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 4930
 0.3
chr13_24782412_24782563 0.13 SPATA13
 spermatogenesis associated 13
 43345
 0.13
chr9_22006120_22006693 0.13 CDKN2B
 cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
 2546
 0.22
chr8_131206670_131206845 0.12 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 13649
 0.23
chr12_94134651_94134921 0.12 RP11-887P2.5
3187
 0.3
chr13_80913239_80913578 0.12 SPRY2
 sprouty homolog 2 (Drosophila)
 386
 0.91
chr21_47064838_47064989 0.12 PCBP3
 poly(rC) binding protein 3
 1305
 0.55
chr1_158150876_158151479 0.12 CD1D
 CD1d molecule
 1440
 0.48
chr12_109344609_109344760 0.12 ENSG00000201324
 .
 24367
 0.14
chr1_1259044_1259204 0.12 CPSF3L
 cleavage and polyadenylation specific factor 3-like
 865
 0.26
chr10_119132010_119132432 0.12 PDZD8
 PDZ domain containing 8
 2757
 0.3
chr10_6779919_6780270 0.12 PRKCQ
 protein kinase C, theta
 157831
 0.04
chr17_27048575_27048801 0.12 ENSG00000238578
 .
 912
 0.15
chr11_122177788_122178312 0.12 RP11-716H6.2
12152
 0.26
chr1_27809144_27809295 0.12 WASF2
 WAS protein family, member 2
 7343
 0.18
chr1_40358588_40359026 0.12 RP1-118J21.5
4610
 0.14
chr5_16701908_16702059 0.12 MYO10
 myosin X
 36513
 0.17
chr19_1747120_1747271 0.12 ONECUT3
 one cut homeobox 3
 5177
 0.15
chr16_13401641_13401792 0.12 AC003009.1
24724
 0.26
chr14_85882041_85882312 0.12 RP11-497E19.2
 Uncharacterized protein
 112767
 0.07
chr19_45147190_45148055 0.12 PVR
 poliovirus receptor
 225
 0.9
chr8_61432570_61432721 0.12 RAB2A
 RAB2A, member RAS oncogene family
 2905
 0.3
chr17_64464860_64465690 0.12 RP11-4F22.2
52303
 0.15
chr6_163838395_163838889 0.12 QKI
 QKI, KH domain containing, RNA binding
 1295
 0.63
chr16_48611180_48611331 0.12 RP11-44I10.3
17683
 0.18
chr21_34800838_34800989 0.12 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
 3713
 0.19
chr2_58654566_58655399 0.12 FANCL
 Fanconi anemia, complementation group L
 186475
 0.03
chr1_210473057_210473208 0.12 HHAT
 hedgehog acyltransferase
 28464
 0.19
chrX_10587307_10587547 0.12 MID1
 midline 1 (Opitz/BBB syndrome)
 1032
 0.65
chr2_65889672_65889956 0.12 ENSG00000265899
 .
 4576
 0.32
chr1_226846201_226846352 0.11 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 1095
 0.55
chrX_154300630_154300860 0.11 BRCC3
 BRCA1/BRCA2-containing complex, subunit 3
 941
 0.32
chr18_26737213_26737364 0.11 ENSG00000212085
 .
 39204
 0.19
chr4_75481668_75481819 0.11 AREGB
 amphiregulin B
 1114
 0.52
chr4_149087230_149087381 0.11 RP11-76G10.1
19683
 0.29
chr5_58830530_58830681 0.11 PDE4D
 phosphodiesterase 4D, cAMP-specific
 51614
 0.19
chr4_75311912_75312063 0.11 AREG
 amphiregulin
 968
 0.58
chr13_38920865_38921016 0.11 UFM1
 ubiquitin-fold modifier 1
 3048
 0.41
chr16_74670457_74670608 0.11 GLG1
 golgi glycoprotein 1
 29520
 0.15
chr9_86955099_86955250 0.11 SLC28A3
 solute carrier family 28 (concentrative nucleoside transporter), member 3
 424
 0.9
chr4_83290764_83291010 0.11 HNRNPD
 heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
 3416
 0.22
chr1_186798918_186799215 0.11 PLA2G4A
 phospholipase A2, group IVA (cytosolic, calcium-dependent)
 944
 0.73
chr7_12981455_12981606 0.11 ENSG00000222974
 .
 65221
 0.15
chrY_2620597_2620748 0.11 ENSG00000251841
 .
 32118
 0.19
chr12_123377992_123378152 0.11 VPS37B
 vacuolar protein sorting 37 homolog B (S. cerevisiae)
 2602
 0.24
chr9_72726451_72726602 0.11 MAMDC2-AS1
 MAMDC2 antisense RNA 1
 2250
 0.38
chr15_27536252_27536403 0.11 ENSG00000200326
 .
 10744
 0.21
chr15_71035707_71036127 0.11 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 19852
 0.21
chr5_58592476_58593460 0.11 PDE4D
 phosphodiesterase 4D, cAMP-specific
 21023
 0.29
chr3_132316510_132316661 0.11 ACKR4
 atypical chemokine receptor 4
 504
 0.83
chr1_68695889_68696040 0.11 WLS
 wntless Wnt ligand secretion mediator
 1406
 0.51
chr4_54458245_54458396 0.11 LNX1
 ligand of numb-protein X 1, E3 ubiquitin protein ligase
 388
 0.72
chr6_27647378_27647849 0.11 ENSG00000238648
 .
 48425
 0.11
chr7_87503109_87503295 0.11 DBF4
 DBF4 homolog (S. cerevisiae)
 2342
 0.29
chr1_108230763_108230914 0.11 VAV3
 vav 3 guanine nucleotide exchange factor
 288
 0.95
chr15_99416784_99417194 0.11 IGF1R
 insulin-like growth factor 1 receptor
 16581
 0.2
chr9_684288_685148 0.11 RP11-130C19.3
837
 0.67
chr9_19377459_19377736 0.11 RP11-513M16.8
2148
 0.21
chr14_91337609_91337760 0.10 TTC7B
 tetratricopeptide repeat domain 7B
 54861
 0.15
chr10_116055069_116055220 0.10 VWA2
 von Willebrand factor A domain containing 2
 56055
 0.13
chr16_14398873_14399280 0.10 ENSG00000207639
 .
 1252
 0.44
chr5_76112526_76112677 0.10 F2RL1
 coagulation factor II (thrombin) receptor-like 1
 2157
 0.27
chr12_54090350_54090675 0.10 CALCOCO1
 calcium binding and coiled-coil domain 1
 17901
 0.15
chr14_85999097_85999705 0.10 FLRT2
 fibronectin leucine rich transmembrane protein 2
 2829
 0.32
chr1_151432125_151432340 0.10 POGZ
 pogo transposable element with ZNF domain
 291
 0.85
chr6_86303657_86304481 0.10 SNX14
 sorting nexin 14
 195
 0.95
chr1_152475138_152475289 0.10 LCE5A
 late cornified envelope 5A
 8107
 0.15
chr15_59642585_59642838 0.10 ENSG00000199512
 .
 9095
 0.13
chr6_160209552_160210274 0.10 TCP1
 t-complex 1
 13
 0.95
chr13_62634734_62634885 0.10 ENSG00000212007
 .
 300300
 0.01
chr7_33080072_33080440 0.10 NT5C3A
 5'-nucleotidase, cytosolic IIIA
 265
 0.9
chr6_56517425_56517576 0.10 DST
 dystonin
 9706
 0.31
chr19_14630525_14630676 0.10 DNAJB1
 DnaJ (Hsp40) homolog, subfamily B, member 1
 1368
 0.27
chr18_52988378_52989650 0.10 TCF4
 transcription factor 4
 203
 0.97
chr10_21807539_21808360 0.10 SKIDA1
 SKI/DACH domain containing 1
 1101
 0.4
chr8_1942200_1942351 0.10 KBTBD11
 kelch repeat and BTB (POZ) domain containing 11
 20231
 0.23
chr5_150477046_150477197 0.10 TNIP1
 TNFAIP3 interacting protein 1
 3983
 0.23
chr13_80916504_80917060 0.10 SPRY2
 sprouty homolog 2 (Drosophila)
 1696
 0.48
chr7_25902294_25902669 0.10 ENSG00000199085
 .
 87125
 0.1
chr5_179495571_179495863 0.10 RNF130
 ring finger protein 130
 3004
 0.28
chr19_46957215_46957366 0.10 PNMAL1
 paraneoplastic Ma antigen family-like 1
 17374
 0.12
chr2_72463375_72463664 0.10 CYP26B1
 cytochrome P450, family 26, subfamily B, polypeptide 1
 88352
 0.11
chr2_135676446_135677712 0.10 CCNT2
 cyclin T2
 684
 0.48
chr2_187354223_187354374 0.10 ZC3H15
 zinc finger CCCH-type containing 15
 3318
 0.24
chr4_178495229_178495380 0.10 ENSG00000221499
 .
 29586
 0.22
chr1_70608576_70608727 0.10 ENSG00000244389
 .
 37472
 0.16
chr13_103424804_103424955 0.10 TEX30
 testis expressed 30
 1226
 0.34
chr2_101945321_101945472 0.10 ENSG00000264857
 .
 19484
 0.16
chr10_122725495_122725646 0.10 RP11-95I16.4
85391
 0.1
chr16_65566073_65566543 0.10 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 410040
 0.01
chr4_157502928_157503125 0.10 RP11-171N4.2
 Uncharacterized protein
 60433
 0.14
chr3_1830304_1830455 0.10 ENSG00000223040
 .
 300516
 0.01
chr3_189743937_189744088 0.10 ENSG00000265045
 .
 87711
 0.08
chr7_20372921_20373226 0.10 CTA-293F17.1
1703
 0.35
chr12_53785686_53785892 0.10 SP1
 Sp1 transcription factor
 10703
 0.12
chr7_129425019_129425280 0.10 ENSG00000207691
 .
 10295
 0.15
chr20_47440971_47441122 0.10 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 3374
 0.34
chr2_178187990_178188141 0.10 AC074286.1
173
 0.92
chr22_29280779_29281052 0.10 ZNRF3
 zinc and ring finger 3
 1025
 0.55
chr4_127698376_127698531 0.10 ENSG00000199862
 .
 250921
 0.02
chr6_152085356_152085807 0.10 ESR1
 estrogen receptor 1
 39985
 0.18
chr3_47822404_47822881 0.10 SMARCC1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
 765
 0.62
chr20_35120205_35120468 0.10 DLGAP4
 discs, large (Drosophila) homolog-associated protein 4
 30186
 0.14
chr9_33080885_33081164 0.10 SMU1
 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
 4359
 0.2
chr17_59534634_59534785 0.10 TBX4
 T-box 4
 902
 0.53
chr5_114970068_114970545 0.10 TMED7
 transmembrane emp24 protein transport domain containing 7
 1617
 0.33
chr3_18418529_18418680 0.10 RP11-158G18.1
32523
 0.19
chr6_98566372_98566523 0.10 ENSG00000238367
 .
 94040
 0.1
chr11_12824646_12824913 0.10 RP11-47J17.3
20435
 0.2
chr12_84188120_84188271 0.10 ENSG00000221148
 .
 389032
 0.01
chr15_62599027_62599178 0.10 RP11-299H22.5
36223
 0.17
chr1_164652386_164652537 0.10 RP11-477H21.2
3139
 0.29
chr5_149857239_149857390 0.10 NDST1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 8067
 0.18
chr16_82172666_82172817 0.10 RP11-510J16.5
495
 0.79
chr6_28175291_28175856 0.10 ZSCAN9
 zinc finger and SCAN domain containing 9
 17091
 0.12
chr15_61963769_61963920 0.09 ENSG00000266349
 .
 72296
 0.13
chr3_107806842_107807168 0.09 CD47
 CD47 molecule
 2856
 0.4
chr3_142607235_142608274 0.09 PCOLCE2
 procollagen C-endopeptidase enhancer 2
 13
 0.98
chr10_33251129_33251359 0.09 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 967
 0.68
chr11_93123532_93123683 0.09 CCDC67
 coiled-coil domain containing 67
 6973
 0.23
chr1_10511739_10511890 0.09 CORT
 cortistatin
 1843
 0.2
chr20_52516714_52516865 0.09 AC005220.3
39910
 0.19
chr5_142585460_142585745 0.09 ARHGAP26
 Rho GTPase activating protein 26
 1161
 0.58
chr10_103813684_103813835 0.09 C10orf76
 chromosome 10 open reading frame 76
 2191
 0.26
chr2_212272854_212273005 0.09 ENSG00000199585
 .
 127449
 0.06
chr1_152010543_152010714 0.09 S100A11
 S100 calcium binding protein A11
 1117
 0.44
chr22_36233928_36234199 0.09 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 2202
 0.43
chr1_10124465_10124616 0.09 UBE4B
 ubiquitination factor E4B
 30886
 0.14
chr4_120987081_120987232 0.09 RP11-679C8.2
957
 0.45
chr17_75128680_75128831 0.09 SEC14L1
 SEC14-like 1 (S. cerevisiae)
 4800
 0.22
chr5_38854613_38854764 0.09 OSMR
 oncostatin M receptor
 8587
 0.28
chrX_31477449_31477600 0.09 ENSG00000252903
 .
 111215
 0.07
chr14_89507425_89507846 0.09 FOXN3
 forkhead box N3
 139453
 0.05
chr1_158123360_158123511 0.09 CD1D
 CD1d molecule
 26302
 0.19
chr9_75566785_75567046 0.09 ALDH1A1
 aldehyde dehydrogenase 1 family, member A1
 1056
 0.7
chr21_38081043_38081194 0.09 SIM2
 single-minded family bHLH transcription factor 2
 363
 0.88
chr7_18549761_18549974 0.09 HDAC9
 histone deacetylase 9
 931
 0.71

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HMGA2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.2 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.1 GO:0042253 granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0042253)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.0 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.0 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0097709 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.0 GO:0002097 tRNA wobble base modification(GO:0002097) tRNA wobble uridine modification(GO:0002098) tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:1903170 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0 0.0 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0090267 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.0 GO:0005826 actomyosin contractile ring(GO:0005826)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.0 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis