Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HMX1

Z-value: 0.41

Motif logo

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Transcription factors associated with HMX1

Gene Symbol Gene ID Gene Info
ENSG00000215612.5 HMX1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HMX1chr4_8940977_8941128675090.098319-0.402.8e-01Click!

Activity of the HMX1 motif across conditions

Conditions sorted by the z-value of the HMX1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_175497594_175497986 0.26 WIPF1
WAS/WASL interacting protein family, member 1
1517
0.45
chr17_62097338_62097710 0.21 ICAM2
intercellular adhesion molecule 2
387
0.83
chr17_76823234_76823385 0.20 USP36
ubiquitin specific peptidase 36
1737
0.32
chr19_54815773_54815924 0.20 LILRA3
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3
5896
0.1
chr2_144855004_144855155 0.18 GTDC1
glycosyltransferase-like domain containing 1
138225
0.05
chr22_20818482_20818633 0.17 ENSG00000255156
.
11041
0.09
chr11_128392558_128393039 0.17 ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
593
0.77
chr14_101586704_101586913 0.17 ENSG00000206761
.
25224
0.04
chr22_37881738_37882044 0.15 MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
534
0.71
chr12_133346878_133347204 0.15 ANKLE2
ankyrin repeat and LEM domain containing 2
8567
0.15
chr5_90678270_90678948 0.14 ARRDC3
arrestin domain containing 3
567
0.83
chr6_53200265_53200465 0.14 ELOVL5
ELOVL fatty acid elongase 5
13222
0.2
chr11_3849313_3849464 0.14 RHOG
ras homolog family member G
2493
0.15
chr9_132648514_132648803 0.14 FNBP1
formin binding protein 1
32931
0.12
chr1_192130381_192130596 0.13 RGS18
regulator of G-protein signaling 18
2901
0.41
chr1_28503293_28503444 0.13 PTAFR
platelet-activating factor receptor
331
0.81
chr17_56412846_56413076 0.13 ENSG00000264399
.
422
0.69
chr16_57334462_57334613 0.13 PLLP
plasmolipin
15938
0.14
chr7_106505707_106506635 0.12 PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
247
0.95
chr11_47397838_47397989 0.12 SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
2029
0.17
chr1_160614614_160614765 0.12 SLAMF1
signaling lymphocytic activation molecule family member 1
2122
0.27
chr9_140131231_140131459 0.12 TUBB4B
tubulin, beta 4B class IVb
4320
0.07
chr12_4382982_4383628 0.12 CCND2
cyclin D2
367
0.72
chr2_85906566_85906717 0.12 SFTPB
surfactant protein B
10777
0.13
chr10_54514994_54515145 0.11 RP11-556E13.1

100
0.98
chr15_86087225_86087376 0.11 AKAP13
A kinase (PRKA) anchor protein 13
29
0.98
chr1_244979206_244979357 0.11 COX20
COX20 cytochrome C oxidase assembly factor
19343
0.18
chr1_149754304_149754780 0.11 FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
296
0.78
chr1_149369357_149369823 0.11 FCGR1C
Fc fragment of IgG, high affinity Ic, receptor (CD64), pseudogene
233
0.9
chr10_51566009_51566382 0.11 NCOA4
nuclear receptor coactivator 4
965
0.54
chr16_29638502_29638653 0.10 ENSG00000266758
.
27991
0.11
chr8_142219382_142219533 0.10 DENND3
DENN/MADD domain containing 3
17027
0.15
chr11_65307798_65308115 0.10 LTBP3
latent transforming growth factor beta binding protein 3
33
0.95
chr14_105530971_105531214 0.10 GPR132
G protein-coupled receptor 132
675
0.7
chr19_54711508_54711701 0.10 RPS9
ribosomal protein S9
6576
0.08
chr17_81146893_81147147 0.10 METRNL
meteorin, glial cell differentiation regulator-like
95026
0.08
chr17_43301087_43301318 0.10 CTD-2020K17.1

1613
0.2
chr7_105332169_105332578 0.10 ATXN7L1
ataxin 7-like 1
289
0.94
chrX_40869304_40869484 0.10 USP9X
ubiquitin specific peptidase 9, X-linked
75494
0.12
chr1_120935370_120935573 0.10 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
423
0.82
chr2_38607378_38607679 0.09 ATL2
atlastin GTPase 2
3101
0.37
chr17_16117665_16118816 0.09 NCOR1
nuclear receptor corepressor 1
603
0.66
chr22_17082773_17083116 0.09 ENSG00000221084
.
3250
0.22
chr19_47237277_47237428 0.09 ENSG00000222614
.
2217
0.15
chr5_126144250_126144473 0.09 LMNB1
lamin B1
31480
0.19
chrY_289482_289633 0.09 NA
NA
> 106
NA
chr17_37558067_37558428 0.09 CTB-131K11.1

201
0.65
chr18_9914707_9915136 0.09 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
862
0.58
chr6_10528716_10529334 0.09 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
436
0.83
chr17_75878240_75878391 0.09 FLJ45079

344
0.91
chr10_103875323_103875595 0.09 LDB1
LIM domain binding 1
756
0.56
chr11_65695547_65695843 0.09 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
8500
0.09
chr6_22063278_22063579 0.08 ENSG00000222515
.
22345
0.28
chr4_118925834_118925985 0.08 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
29591
0.26
chr9_129295639_129295790 0.08 ENSG00000221768
.
2444
0.31
chr11_128564573_128565732 0.08 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
766
0.51
chr7_102066305_102066456 0.08 ORAI2
ORAI calcium release-activated calcium modulator 2
7173
0.09
chr11_62361155_62361306 0.08 TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
1581
0.16
chr17_66379730_66379881 0.08 ENSG00000207561
.
40884
0.14
chr10_101945955_101946507 0.08 ERLIN1
ER lipid raft associated 1
441
0.76
chr21_36420108_36421159 0.08 RUNX1
runt-related transcription factor 1
829
0.77
chr3_122477747_122477898 0.08 ENSG00000238480
.
8603
0.19
chr19_41329914_41330065 0.08 EGLN2
egl-9 family hypoxia-inducible factor 2
16841
0.11
chr3_53204570_53204956 0.08 PRKCD
protein kinase C, delta
5618
0.19
chr2_242679805_242679956 0.08 D2HGDH
D-2-hydroxyglutarate dehydrogenase
1968
0.18
chr16_11038476_11038796 0.08 CLEC16A
C-type lectin domain family 16, member A
198
0.9
chr20_30639783_30640305 0.08 HCK
hemopoietic cell kinase
1
0.96
chr10_134369040_134369355 0.08 INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
17554
0.21
chr17_73772737_73772888 0.07 H3F3B
H3 histone, family 3B (H3.3B)
2555
0.14
chrX_48775697_48776218 0.07 PIM2
pim-2 oncogene
344
0.77
chr7_2491547_2491962 0.07 CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
48020
0.11
chr9_95726568_95726886 0.07 FGD3
FYVE, RhoGEF and PH domain containing 3
484
0.84
chr5_77147504_77148481 0.07 TBCA
tubulin folding cofactor A
16612
0.28
chr12_2453066_2453260 0.07 CACNA1C-IT3
CACNA1C intronic transcript 3 (non-protein coding)
74221
0.11
chr19_8639062_8639292 0.07 MYO1F
myosin IF
3145
0.16
chr2_99082083_99082234 0.07 INPP4A
inositol polyphosphate-4-phosphatase, type I, 107kDa
20745
0.22
chr1_208712376_208712638 0.07 PLXNA2
plexin A2
294842
0.01
chr17_76255043_76255413 0.07 TMEM235
transmembrane protein 235
27106
0.12
chr16_84421_84572 0.07 WASIR2
WASH and IL9R antisense RNA 2
11586
0.1
chr19_45621503_45621654 0.07 AC005757.6

18657
0.08
chr8_134086953_134087155 0.07 SLA
Src-like-adaptor
14451
0.23
chr19_51728373_51728524 0.07 CD33
CD33 molecule
94
0.94
chr17_19883077_19883228 0.07 AKAP10
A kinase (PRKA) anchor protein 10
2002
0.3
chr14_58666937_58667480 0.07 ACTR10
actin-related protein 10 homolog (S. cerevisiae)
352
0.84
chr17_4389201_4389708 0.07 RP13-580F15.2

194
0.92
chr4_80993397_80993717 0.07 ANTXR2
anthrax toxin receptor 2
160
0.97
chr19_3178230_3178381 0.06 S1PR4
sphingosine-1-phosphate receptor 4
431
0.74
chr6_88973481_88973632 0.06 CNR1
cannabinoid receptor 1 (brain)
97478
0.09
chr21_37572727_37572878 0.06 ENSG00000265882
.
13334
0.14
chr22_17700031_17700512 0.06 CECR1
cat eye syndrome chromosome region, candidate 1
5
0.98
chr11_9285524_9286554 0.06 DENND5A
DENN/MADD domain containing 5A
595
0.74
chr6_37017159_37017310 0.06 COX6A1P2
cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2
4627
0.23
chr15_73928751_73928902 0.06 NPTN
neuroplastin
2351
0.36
chr1_236105367_236105518 0.06 ENSG00000206803
.
26727
0.17
chr16_29984700_29984855 0.06 TAOK2
TAO kinase 2
185
0.87
chr20_62434745_62434896 0.06 RP4-583P15.11

4609
0.11
chr13_49065462_49065706 0.06 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
41629
0.17
chr3_151987094_151987576 0.06 MBNL1-AS1
MBNL1 antisense RNA 1
0
0.58
chr1_160990016_160990876 0.06 F11R
F11 receptor
440
0.71
chr16_30583519_30583791 0.06 ZNF688
zinc finger protein 688
73
0.49
chr1_54821806_54822159 0.06 SSBP3
single stranded DNA binding protein 3
49195
0.13
chrX_37640522_37640673 0.06 CYBB
cytochrome b-245, beta polypeptide
1280
0.54
chr8_22563265_22563416 0.06 EGR3
early growth response 3
12525
0.13
chr10_45464087_45464238 0.06 RASSF4
Ras association (RalGDS/AF-6) domain family member 4
1510
0.28
chr2_202097823_202098101 0.06 CASP8
caspase 8, apoptosis-related cysteine peptidase
204
0.94
chr9_71319950_71320419 0.06 PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
391
0.9
chr1_27147150_27147301 0.06 ENSG00000241188
.
5912
0.12
chr12_129280330_129280481 0.06 SLC15A4
solute carrier family 15 (oligopeptide transporter), member 4
5841
0.28
chr12_40618871_40619488 0.06 LRRK2
leucine-rich repeat kinase 2
303
0.89
chr11_6640777_6640928 0.06 TPP1
tripeptidyl peptidase I
160
0.82
chr20_23028362_23028696 0.06 THBD
thrombomodulin
1849
0.28
chr14_93579935_93580162 0.06 ITPK1
inositol-tetrakisphosphate 1-kinase
1569
0.39
chr12_125052371_125052867 0.06 NCOR2
nuclear receptor corepressor 2
609
0.84
chr13_52212503_52212693 0.06 ENSG00000242893
.
44247
0.11
chr17_39655103_39655254 0.06 AC019349.5

2057
0.14
chr14_91830192_91830394 0.06 ENSG00000265856
.
30236
0.18
chrX_44173865_44174016 0.06 EFHC2
EF-hand domain (C-terminal) containing 2
28978
0.24
chr20_4794055_4794206 0.06 RASSF2
Ras association (RalGDS/AF-6) domain family member 2
1639
0.4
chr6_110011634_110011785 0.06 AK9
adenylate kinase 9
0
0.95
chr12_125478431_125478707 0.06 BRI3BP
BRI3 binding protein
323
0.89
chr7_5862773_5862988 0.06 ZNF815P
zinc finger protein 815, pseudogene
42
0.97
chr3_112686562_112686713 0.06 CD200R1
CD200 receptor 1
7122
0.17
chr20_62714432_62714977 0.06 C20orf201
chromosome 20 open reading frame 201
1008
0.3
chr15_51913253_51913493 0.06 DMXL2
Dmx-like 2
1459
0.4
chr1_145437718_145438228 0.06 TXNIP
thioredoxin interacting protein
496
0.69
chr3_4536182_4536507 0.06 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
1110
0.44
chr1_153917802_153918374 0.06 DENND4B
DENN/MADD domain containing 4B
343
0.75
chr12_8234042_8234677 0.06 NECAP1
NECAP endocytosis associated 1
448
0.78
chr9_4942396_4942547 0.06 ENSG00000238362
.
25626
0.17
chr7_135656031_135656246 0.05 MTPN
myotrophin
5926
0.18
chr19_10748205_10748356 0.05 SLC44A2
solute carrier family 44 (choline transporter), member 2
40
0.96
chr6_32156796_32157600 0.05 PBX2
pre-B-cell leukemia homeobox 2
765
0.38
chr2_171571264_171571992 0.05 SP5
Sp5 transcription factor
233
0.76
chr15_67356717_67357002 0.05 SMAD3
SMAD family member 3
758
0.77
chr19_49243178_49243445 0.05 RASIP1
Ras interacting protein 1
667
0.48
chr4_38784523_38784674 0.05 TLR10
toll-like receptor 10
9
0.97
chr16_88878512_88878743 0.05 APRT
adenine phosphoribosyltransferase
275
0.82
chr17_76381899_76382050 0.05 PGS1
phosphatidylglycerophosphate synthase 1
7215
0.14
chr7_29628654_29628805 0.05 PRR15
proline rich 15
23663
0.17
chr17_72527307_72527458 0.05 CD300LB
CD300 molecule-like family member b
223
0.91
chr17_38486750_38487092 0.05 RARA
retinoic acid receptor, alpha
10719
0.11
chr12_102090642_102091223 0.05 CHPT1
choline phosphotransferase 1
473
0.75
chr3_126191945_126192170 0.05 ZXDC
ZXD family zinc finger C
2651
0.25
chr5_37370451_37371178 0.05 NUP155
nucleoporin 155kDa
73
0.98
chr6_7145795_7146333 0.05 RREB1
ras responsive element binding protein 1
6586
0.22
chr19_2290091_2290388 0.05 LINGO3
leucine rich repeat and Ig domain containing 3
1784
0.18
chr6_5026001_5026185 0.05 ENSG00000252419
.
20242
0.19
chr1_202457690_202457841 0.05 PPP1R12B
protein phosphatase 1, regulatory subunit 12B
25894
0.17
chr11_59554604_59554755 0.05 STX3
syntaxin 3
139
0.95
chr17_43334091_43334242 0.05 MAP3K14-AS1
MAP3K14 antisense RNA 1
1775
0.2
chrX_153284800_153285224 0.05 IRAK1
interleukin-1 receptor-associated kinase 1
239
0.66
chr14_70104707_70105002 0.05 KIAA0247
KIAA0247
26541
0.2
chr1_206729975_206731239 0.05 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
114
0.96
chr12_65004453_65004740 0.05 RASSF3
Ras association (RalGDS/AF-6) domain family member 3
303
0.81
chr3_71631883_71632034 0.05 FOXP1
forkhead box P1
946
0.6
chr15_75077997_75078148 0.05 CSK
c-src tyrosine kinase
2813
0.16
chr16_28996496_28996848 0.05 LAT
linker for activation of T cells
11
0.94
chr14_98108128_98108342 0.05 ENSG00000240730
.
111725
0.07
chr19_3505802_3505997 0.05 FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
372
0.73
chr19_2096024_2096259 0.05 MOB3A
MOB kinase activator 3A
128
0.64
chr1_167522333_167523011 0.05 CREG1
cellular repressor of E1A-stimulated genes 1
332
0.9
chr1_92942181_92942332 0.05 GFI1
growth factor independent 1 transcription repressor
7255
0.27
chr11_111741428_111741733 0.05 ALG9
ALG9, alpha-1,2-mannosyltransferase
8
0.96
chr3_53736497_53736648 0.05 CACNA1D
calcium channel, voltage-dependent, L type, alpha 1D subunit
36144
0.17
chr2_67610232_67610383 0.05 ETAA1
Ewing tumor-associated antigen 1
14144
0.32
chr15_91372562_91372713 0.05 CTD-3094K11.1

10317
0.13
chr12_52294368_52294519 0.05 ACVRL1
activin A receptor type II-like 1
6249
0.18
chr21_29782788_29782939 0.04 ENSG00000251894
.
332667
0.01
chr13_25085743_25086881 0.04 PARP4
poly (ADP-ribose) polymerase family, member 4
636
0.74
chr11_65292001_65292182 0.04 SCYL1
SCY1-like 1 (S. cerevisiae)
457
0.69
chr6_13434336_13434487 0.04 GFOD1
glucose-fructose oxidoreductase domain containing 1
26042
0.17
chr6_2901280_2901469 0.04 SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
2140
0.3
chr12_6447373_6447724 0.04 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
3466
0.15
chr6_149771705_149771910 0.04 ZC3H12D
zinc finger CCCH-type containing 12D
6198
0.19
chr10_90593250_90593401 0.04 ANKRD22
ankyrin repeat domain 22
18250
0.16
chr1_235097453_235097604 0.04 ENSG00000239690
.
57595
0.14
chr15_81591495_81592151 0.04 IL16
interleukin 16
66
0.98
chr15_65117601_65117801 0.04 PIF1
PIF1 5'-to-3' DNA helicase
137
0.94
chr14_56584316_56584807 0.04 PELI2
pellino E3 ubiquitin protein ligase family member 2
29
0.98
chr21_46347709_46348073 0.04 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
742
0.47
chr8_142384090_142384264 0.04 GPR20
G protein-coupled receptor 20
6810
0.12
chr10_31073473_31074431 0.04 RP11-330O11.3

48364
0.15
chrX_71341466_71341617 0.04 RGAG4
retrotransposon gag domain containing 4
10137
0.16
chr11_5646501_5646907 0.04 TRIM34
tripartite motif containing 34
491
0.45
chr3_4535116_4535869 0.04 ITPR1
inositol 1,4,5-trisphosphate receptor, type 1
258
0.78
chr11_61659243_61659612 0.04 FADS3
fatty acid desaturase 3
96
0.95
chr19_50400763_50401028 0.04 IL4I1
interleukin 4 induced 1
683
0.39
chr11_128595318_128595476 0.04 SENCR
smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
29479
0.16
chr3_138594988_138595139 0.04 PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
41283
0.15
chr22_37310592_37310811 0.04 CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
1026
0.44
chr17_72588244_72588395 0.04 CD300LD
CD300 molecule-like family member d
103
0.94
chr1_65885426_65885920 0.04 LEPR
leptin receptor
575
0.45
chr22_37639776_37640249 0.04 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
276
0.88
chr15_41695201_41695405 0.04 NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
586
0.69
chr2_10091778_10091990 0.04 GRHL1
grainyhead-like 1 (Drosophila)
57
0.98
chr6_53109316_53109571 0.04 ENSG00000206908
.
25384
0.15
chr17_47840030_47840441 0.04 FAM117A
family with sequence similarity 117, member A
1258
0.41
chr14_76620742_76620893 0.04 GPATCH2L
G patch domain containing 2-like
828
0.72
chr1_206731858_206732141 0.04 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
1506
0.37
chr3_13056943_13057225 0.04 IQSEC1
IQ motif and Sec7 domain 1
28548
0.23

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HMX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.1 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0006168 adenine salvage(GO:0006168) purine nucleobase salvage(GO:0043096) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.1 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0002060 purine nucleobase binding(GO:0002060)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.0 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID S1P S1P4 PATHWAY S1P4 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity