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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HMX2

Z-value: 1.04

Motif logo

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Transcription factors associated with HMX2

Gene Symbol Gene ID Gene Info
HMX2
ENSG00000188816.3 H6 family homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_124909040_124909256HMX215100.364450-0.882.0e-03Click!
chr10_124910587_124910809HMX230600.215004-0.771.6e-02Click!
chr10_124909262_124909943HMX219640.293686-0.732.5e-02Click!
chr10_124907467_124907629HMX2900.966834-0.713.3e-02Click!
chr10_124910209_124910577HMX227550.230159-0.703.6e-02Click!

Activity of the HMX2 motif across conditions

Conditions sorted by the z-value of the HMX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_128521797_128522422 0.74 PBX3
 pre-B-cell leukemia homeobox 3
 11631
 0.27
chr4_86749229_86749793 0.66 ARHGAP24
 Rho GTPase activating protein 24
 465
 0.88
chr5_39795068_39795219 0.64 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 332741
 0.01
chr3_128950544_128950778 0.60 COPG1
 coatomer protein complex, subunit gamma 1
 17788
 0.14
chr3_87036535_87037613 0.57 VGLL3
 vestigial like 3 (Drosophila)
 2778
 0.42
chr2_185461919_185462338 0.55 ZNF804A
 zinc finger protein 804A
 965
 0.73
chr4_85886471_85886934 0.54 WDFY3
 WD repeat and FYVE domain containing 3
 801
 0.75
chr3_154802044_154802331 0.54 MME
 membrane metallo-endopeptidase
 454
 0.9
chr18_74810332_74810710 0.54 MBP
 myelin basic protein
 6696
 0.31
chr1_181474291_181474442 0.47 CACNA1E
 calcium channel, voltage-dependent, R type, alpha 1E subunit
 21485
 0.28
chr12_49626686_49627168 0.46 TUBA1C
 tubulin, alpha 1c
 5218
 0.14
chr5_71852161_71852865 0.46 ZNF366
 zinc finger protein 366
 48959
 0.17
chr8_142141679_142142152 0.45 RP11-809O17.1
1855
 0.33
chr20_44637987_44638138 0.45 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
 515
 0.69
chr12_26276607_26276969 0.44 BHLHE41
 basic helix-loop-helix family, member e41
 1272
 0.35
chr5_10607689_10607893 0.44 ANKRD33B-AS1
 ANKRD33B antisense RNA 1
 20546
 0.2
chr4_87516254_87516849 0.44 PTPN13
 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
 295
 0.87
chr10_74454607_74455259 0.44 MCU
 mitochondrial calcium uniporter
 2556
 0.25
chr3_114790766_114791082 0.43 ZBTB20
 zinc finger and BTB domain containing 20
 702
 0.82
chr6_114178016_114178613 0.43 MARCKS
 myristoylated alanine-rich protein kinase C substrate
 227
 0.93
chr2_61154150_61154439 0.43 ENSG00000201076
 .
 15856
 0.18
chr2_145266588_145266958 0.43 ZEB2
 zinc finger E-box binding homeobox 2
 8342
 0.25
chr13_24146066_24146217 0.43 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 1338
 0.59
chr5_17436444_17436999 0.42 ENSG00000201715
 .
 90996
 0.09
chr2_171571264_171571992 0.42 SP5
 Sp5 transcription factor
 233
 0.76
chr8_68304896_68305241 0.42 ARFGEF1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
 49156
 0.18
chr20_52539385_52539536 0.42 AC005220.3
17239
 0.25
chr6_138280285_138280436 0.41 RP11-356I2.4
90990
 0.08
chr6_168258633_168258838 0.41 MLLT4
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
 22426
 0.22
chr4_157891142_157892336 0.41 PDGFC
 platelet derived growth factor C
 316
 0.91
chr12_8724646_8724797 0.39 ENSG00000238943
 .
 20351
 0.12
chr5_16934329_16934610 0.39 MYO10
 myosin X
 1578
 0.42
chr4_15659797_15659948 0.39 FBXL5
 F-box and leucine-rich repeat protein 5
 1615
 0.4
chr20_23062504_23062655 0.39 CD93
 CD93 molecule
 4398
 0.2
chr11_61690264_61690511 0.39 RAB3IL1
 RAB3A interacting protein (rabin3)-like 1
 2646
 0.18
chr8_128003605_128003873 0.38 ENSG00000212451
 .
 319972
 0.01
chr1_14057621_14057780 0.38 PRDM2
 PR domain containing 2, with ZNF domain
 18198
 0.21
chr1_158801859_158802010 0.38 MNDA
 myeloid cell nuclear differentiation antigen
 827
 0.63
chrX_124324124_124324275 0.38 ENSG00000263886
 .
 97426
 0.09
chr18_6879021_6879172 0.38 RP11-146G7.2
4073
 0.22
chr16_53403757_53403908 0.38 RP11-44F14.1
3163
 0.23
chr15_38164800_38165190 0.38 TMCO5A
 transmembrane and coiled-coil domains 5A
 49145
 0.2
chr13_99698714_99698945 0.38 ENSG00000207298
 .
 21341
 0.18
chr1_112158809_112159009 0.37 RAP1A
 RAP1A, member of RAS oncogene family
 3490
 0.23
chr3_11651207_11651493 0.37 VGLL4
 vestigial like 4 (Drosophila)
 628
 0.65
chr7_41909638_41910025 0.37 AC005027.3
164898
 0.04
chr5_150439052_150439203 0.37 TNIP1
 TNFAIP3 interacting protein 1
 5529
 0.21
chr3_106917310_106917540 0.37 ENSG00000220989
 .
 166604
 0.04
chr3_171779467_171780048 0.37 FNDC3B
 fibronectin type III domain containing 3B
 15054
 0.27
chr9_86088128_86088424 0.37 ENSG00000252256
 .
 7906
 0.21
chr10_17256481_17257128 0.36 VIM-AS1
 VIM antisense RNA 1
 12093
 0.15
chr22_18260542_18260943 0.36 BID
 BH3 interacting domain death agonist
 3311
 0.23
chr9_32558730_32559019 0.36 TOPORS
 topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
 6323
 0.14
chr1_57041430_57041821 0.36 PPAP2B
 phosphatidic acid phosphatase type 2B
 3616
 0.34
chr11_48089034_48089185 0.36 ENSG00000263693
 .
 29225
 0.18
chr1_185014704_185016028 0.36 RNF2
 ring finger protein 2
 138
 0.97
chrX_12925475_12925626 0.36 TLR8
 toll-like receptor 8
 792
 0.45
chrX_70273312_70273567 0.35 SNX12
 sorting nexin 12
 14814
 0.12
chr19_2185882_2186045 0.35 DOT1L
 DOT1-like histone H3K79 methyltransferase
 21779
 0.09
chr6_143508631_143508782 0.35 AIG1
 androgen-induced 1
 61319
 0.13
chr12_10221089_10221341 0.35 ENSG00000223042
 .
 15570
 0.12
chrX_118710010_118710161 0.35 UBE2A
 ubiquitin-conjugating enzyme E2A
 1445
 0.35
chr12_68762043_68762194 0.35 MDM1
 Mdm1 nuclear protein homolog (mouse)
 35957
 0.21
chr16_17547681_17547832 0.35 XYLT1
 xylosyltransferase I
 16982
 0.31
chr2_141580056_141580207 0.34 ENSG00000201892
 .
 169981
 0.04
chr21_34777490_34777711 0.34 IFNGR2
 interferon gamma receptor 2 (interferon gamma transducer 1)
 1828
 0.33
chr7_111724314_111724465 0.34 DOCK4
 dedicator of cytokinesis 4
 80203
 0.1
chr6_56707059_56707245 0.34 DST
 dystonin
 791
 0.6
chr12_107383429_107383607 0.34 MTERFD3
 MTERF domain containing 3
 2574
 0.25
chr13_32606969_32607251 0.34 FRY-AS1
 FRY antisense RNA 1
 1334
 0.41
chr11_72519643_72519794 0.34 ATG16L2
 autophagy related 16-like 2 (S. cerevisiae)
 5635
 0.13
chr7_27237323_27237633 0.34 HOTTIP
 HOXA distal transcript antisense RNA
 716
 0.38
chr2_54684867_54685285 0.34 SPTBN1
 spectrin, beta, non-erythrocytic 1
 678
 0.77
chr3_112362286_112362437 0.34 CCDC80
 coiled-coil domain containing 80
 2214
 0.38
chr3_112685164_112685315 0.34 CD200R1
 CD200 receptor 1
 8520
 0.16
chr10_51574745_51574998 0.34 NCOA4
 nuclear receptor coactivator 4
 1414
 0.4
chr9_43685064_43685767 0.33 CNTNAP3B
 contactin associated protein-like 3B
 505
 0.86
chr4_147027155_147027306 0.33 ENSG00000216055
 .
 16206
 0.24
chr2_219247924_219248075 0.33 SLC11A1
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
 967
 0.35
chr17_30830669_30830820 0.33 RP11-466A19.1
8190
 0.11
chr8_97172057_97172969 0.33 GDF6
 growth differentiation factor 6
 507
 0.84
chr18_9712643_9712794 0.33 RAB31
 RAB31, member RAS oncogene family
 4556
 0.26
chr8_38855409_38855789 0.33 ADAM9
 ADAM metallopeptidase domain 9
 1094
 0.34
chrX_41308603_41308816 0.33 NYX
 nyctalopin
 1996
 0.38
chr16_81577563_81578015 0.33 CMIP
 c-Maf inducing protein
 48835
 0.17
chr2_33360143_33360339 0.33 LTBP1
 latent transforming growth factor beta binding protein 1
 517
 0.87
chr11_61890885_61891204 0.33 INCENP
 inner centromere protein antigens 135/155kDa
 401
 0.85
chr16_9171257_9171408 0.33 C16orf72
 chromosome 16 open reading frame 72
 14173
 0.16
chrX_34673071_34673254 0.32 TMEM47
 transmembrane protein 47
 2243
 0.48
chr3_11681791_11681953 0.32 VGLL4
 vestigial like 4 (Drosophila)
 3526
 0.27
chr15_55687869_55688020 0.32 CCPG1
 cell cycle progression 1
 2522
 0.25
chr7_77930640_77930829 0.32 RP5-1185I7.1
310997
 0.01
chr10_43636132_43636545 0.32 CSGALNACT2
 chondroitin sulfate N-acetylgalactosaminyltransferase 2
 2404
 0.35
chr17_62152031_62152238 0.32 ICAM2
 intercellular adhesion molecule 2
 54140
 0.09
chr9_89808674_89808967 0.32 C9orf170
 chromosome 9 open reading frame 170
 45261
 0.18
chr12_29310650_29310817 0.32 FAR2
 fatty acyl CoA reductase 2
 8600
 0.26
chr4_39482966_39483117 0.32 LIAS
 lipoic acid synthetase
 22349
 0.12
chr10_28967900_28968168 0.32 BAMBI
 BMP and activin membrane-bound inhibitor
 1763
 0.35
chr20_20687715_20687866 0.32 RALGAPA2
 Ral GTPase activating protein, alpha subunit 2 (catalytic)
 5341
 0.28
chr1_108593288_108593486 0.32 ENSG00000264753
 .
 31994
 0.19
chr2_187405682_187405833 0.32 ZC3H15
 zinc finger CCCH-type containing 15
 34317
 0.15
chr14_102856535_102856686 0.32 TECPR2
 tectonin beta-propeller repeat containing 2
 27194
 0.12
chr9_40632604_40633916 0.32 SPATA31A3
 SPATA31 subfamily A, member 3
 67031
 0.14
chr7_139561328_139561479 0.31 TBXAS1
 thromboxane A synthase 1 (platelet)
 32293
 0.21
chr14_50864063_50864214 0.31 CDKL1
 cyclin-dependent kinase-like 1 (CDC2-related kinase)
 16
 0.98
chr3_194821900_194822051 0.31 XXYLT1-AS1
 XXYLT1 antisense RNA 1
 6658
 0.17
chr5_36403502_36403800 0.31 ENSG00000222178
 .
 81794
 0.09
chr19_50890626_50890777 0.31 POLD1
 polymerase (DNA directed), delta 1, catalytic subunit
 3071
 0.12
chr14_97270675_97270826 0.31 VRK1
 vaccinia related kinase 1
 7109
 0.32
chr1_54197803_54198068 0.31 GLIS1
 GLIS family zinc finger 1
 1942
 0.34
chr10_35645086_35645269 0.31 CCNY
 cyclin Y
 19375
 0.19
chr11_48088403_48088554 0.31 ENSG00000263693
 .
 29856
 0.17
chr5_77147504_77148481 0.31 TBCA
 tubulin folding cofactor A
 16612
 0.28
chr12_40617765_40617916 0.31 AC079630.4
235
 0.88
chr11_124791512_124791663 0.31 HEPN1
 hepatocellular carcinoma, down-regulated 1
 2441
 0.18
chr5_106971001_106971250 0.31 EFNA5
 ephrin-A5
 35203
 0.23
chr6_151457602_151457767 0.30 ENSG00000238616
 .
 64792
 0.09
chr4_88310685_88310836 0.30 HSD17B11
 hydroxysteroid (17-beta) dehydrogenase 11
 1541
 0.31
chr15_80253021_80253172 0.30 BCL2A1
 BCL2-related protein A1
 10415
 0.17
chr6_151088648_151089017 0.30 PLEKHG1
 pleckstrin homology domain containing, family G (with RhoGef domain) member 1
 46608
 0.16
chr17_66289131_66289282 0.30 ARSG
 arylsulfatase G
 1547
 0.31
chr2_237652692_237652863 0.30 ACKR3
 atypical chemokine receptor 3
 174493
 0.03
chr2_190042287_190042516 0.30 COL5A2
 collagen, type V, alpha 2
 2204
 0.37
chr7_139555848_139556033 0.30 TBXAS1
 thromboxane A synthase 1 (platelet)
 26830
 0.22
chr4_87930432_87930664 0.30 AFF1
 AF4/FMR2 family, member 1
 2127
 0.43
chr15_66130236_66130387 0.30 ENSG00000252715
 .
 5511
 0.2
chr8_104090727_104091208 0.30 ENSG00000265667
 .
 13982
 0.15
chrX_38676678_38676829 0.30 MID1IP1-AS1
 MID1IP1 antisense RNA 1
 13617
 0.23
chr15_96878987_96879612 0.30 ENSG00000222651
 .
 2809
 0.21
chr16_69959056_69959289 0.30 WWP2
 WW domain containing E3 ubiquitin protein ligase 2
 279
 0.89
chr17_68169002_68169153 0.30 KCNJ2
 potassium inwardly-rectifying channel, subfamily J, member 2
 3401
 0.24
chr3_3859837_3859988 0.30 LRRN1
 leucine rich repeat neuronal 1
 18791
 0.29
chr18_74188521_74188672 0.29 ZNF516
 zinc finger protein 516
 14139
 0.17
chr1_60036110_60036386 0.29 FGGY
 FGGY carbohydrate kinase domain containing
 16658
 0.29
chr7_105954849_105955000 0.29 NAMPT
 nicotinamide phosphoribosyltransferase
 28152
 0.19
chr10_89826430_89826581 0.29 ENSG00000200891
 .
 72053
 0.12
chr4_154448027_154448178 0.29 KIAA0922
 KIAA0922
 28946
 0.22
chr19_7742927_7743078 0.29 CTD-3214H19.16
385
 0.62
chr12_91575790_91576058 0.29 DCN
 decorin
 505
 0.87
chr8_10000681_10000890 0.29 MSRA
 methionine sulfoxide reductase A
 47548
 0.15
chr3_132036571_132036865 0.29 ACPP
 acid phosphatase, prostate
 467
 0.84
chr12_94520292_94520443 0.29 PLXNC1
 plexin C1
 22132
 0.21
chr20_42136057_42136836 0.29 L3MBTL1
 l(3)mbt-like 1 (Drosophila)
 96
 0.96
chr8_48572289_48573010 0.29 SPIDR
 scaffolding protein involved in DNA repair
 423
 0.86
chr1_120678889_120679040 0.29 ENSG00000207149
 .
 9402
 0.26
chr3_46249431_46249760 0.28 CCR1
 chemokine (C-C motif) receptor 1
 292
 0.92
chr1_59966484_59966635 0.28 FGGY
 FGGY carbohydrate kinase domain containing
 53031
 0.18
chr6_113807870_113808021 0.28 ENSG00000222677
 .
 28244
 0.25
chr6_106700141_106700423 0.28 ENSG00000244710
 .
 31304
 0.17
chr4_15963408_15963559 0.28 FGFBP2
 fibroblast growth factor binding protein 2
 1376
 0.42
chr5_139991416_139991567 0.28 CD14
 CD14 molecule
 21745
 0.07
chr3_114582583_114582774 0.28 ZBTB20
 zinc finger and BTB domain containing 20
 104560
 0.08
chr1_204034501_204034712 0.28 SOX13
 SRY (sex determining region Y)-box 13
 8126
 0.2
chr15_45933944_45934448 0.28 SQRDL
 sulfide quinone reductase-like (yeast)
 3883
 0.22
chr7_129256866_129257092 0.28 NRF1
 nuclear respiratory factor 1
 5382
 0.26
chr2_47537091_47537242 0.28 EPCAM
 epithelial cell adhesion molecule
 35131
 0.15
chr16_62068318_62068835 0.28 CDH8
 cadherin 8, type 2
 462
 0.9
chr6_39082026_39082817 0.28 SAYSD1
 SAYSVFN motif domain containing 1
 544
 0.84
chr22_43325223_43325374 0.28 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 16581
 0.21
chr8_128651347_128651766 0.27 MYC
 v-myc avian myelocytomatosis viral oncogene homolog
 96124
 0.08
chr8_142131148_142131299 0.27 DENND3
 DENN/MADD domain containing 3
 3846
 0.24
chr15_50139702_50139853 0.27 ATP8B4
 ATPase, class I, type 8B, member 4
 29115
 0.19
chr5_147845522_147845673 0.27 CTD-2283N19.1
35227
 0.17
chr7_40509990_40510280 0.27 AC004988.1
76392
 0.12
chr13_31443551_31443843 0.27 MEDAG
 mesenteric estrogen-dependent adipogenesis
 36631
 0.17
chr14_59804248_59804514 0.27 ENSG00000252869
 .
 62360
 0.12
chr12_58237319_58237553 0.27 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
 1881
 0.19
chr8_86971164_86971315 0.27 ATP6V0D2
 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
 28313
 0.23
chr2_70274372_70274523 0.27 PCBP1-AS1
 PCBP1 antisense RNA 1
 6470
 0.18
chr3_114169976_114170457 0.27 ZBTB20
 zinc finger and BTB domain containing 20
 3314
 0.33
chr7_128171824_128173030 0.27 RP11-274B21.1
1279
 0.43
chrX_3379855_3380017 0.27 ENSG00000212214
 .
 70356
 0.11
chr3_99679660_99679890 0.27 ENSG00000264897
 .
 3467
 0.34
chr1_216018877_216019050 0.26 RP5-1111A8.3
40961
 0.22
chr5_53965498_53965649 0.26 SNX18
 sorting nexin 18
 151980
 0.04
chr18_74189277_74189488 0.26 ZNF516
 zinc finger protein 516
 13353
 0.17
chr1_28258300_28258451 0.26 SMPDL3B
 sphingomyelin phosphodiesterase, acid-like 3B
 3129
 0.17
chr14_22025947_22026098 0.26 OR10G3
 olfactory receptor, family 10, subfamily G, member 3
 12853
 0.14
chr11_72700714_72700865 0.26 FCHSD2
 FCH and double SH3 domains 2
 732
 0.75
chr4_113811114_113811345 0.26 RP11-119H12.6
7743
 0.26
chr16_69418841_69419937 0.26 TERF2
 telomeric repeat binding factor 2
 84
 0.95
chr15_91955696_91955847 0.26 SV2B
 synaptic vesicle glycoprotein 2B
 186671
 0.03
chr11_64757608_64757759 0.26 BATF2
 basic leucine zipper transcription factor, ATF-like 2
 62
 0.94
chr3_176005114_176005265 0.26 ENSG00000252302
 .
 475832
 0.01
chr10_15762100_15762293 0.26 ITGA8
 integrin, alpha 8
 72
 0.99
chr17_40157452_40157603 0.26 DNAJC7
 DnaJ (Hsp40) homolog, subfamily C, member 7
 5766
 0.12
chr6_151651846_151651997 0.26 AKAP12
 A kinase (PRKA) anchor protein 12
 5098
 0.14
chr2_157657104_157657488 0.26 ENSG00000263848
 .
 214473
 0.02
chr2_216992578_216992729 0.26 XRCC5
 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
 18579
 0.19
chr18_55448645_55448916 0.26 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 21547
 0.18
chr3_142681892_142682427 0.26 PAQR9
 progestin and adipoQ receptor family member IX
 19
 0.84
chr13_38445031_38445182 0.26 TRPC4
 transient receptor potential cation channel, subfamily C, member 4
 544
 0.83
chr10_69990769_69991228 0.26 ATOH7
 atonal homolog 7 (Drosophila)
 873
 0.64
chr2_200446222_200446758 0.26 SATB2
 SATB homeobox 2
 110501
 0.07
chr3_50281165_50281367 0.26 GNAI2
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
 3060
 0.13
chr8_100559499_100559717 0.26 ENSG00000216069
 .
 10519
 0.16
chr6_144016553_144016704 0.25 PHACTR2
 phosphatase and actin regulator 2
 17423
 0.25
chr2_158113918_158114875 0.25 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 286
 0.93
chr12_46759532_46760006 0.25 SLC38A2
 solute carrier family 38, member 2
 679
 0.75
chr2_6921294_6921445 0.25 AC017076.5
52293
 0.15

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.5 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1 0.3 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0071436 sodium ion export(GO:0071436)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.3 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.1 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.1 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0014041 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.3 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 0.2 GO:0031223 auditory behavior(GO:0031223)
0.1 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1 0.2 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.3 GO:0008354 germ cell migration(GO:0008354)
0.1 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.1 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0060435 bronchiole development(GO:0060435)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:2000831 corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.0 0.1 GO:0002323 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.0 0.2 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.2 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.3 GO:0036296 response to increased oxygen levels(GO:0036296) response to hyperoxia(GO:0055093)
0.0 0.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0014805 smooth muscle adaptation(GO:0014805)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.1 GO:0021984 adenohypophysis development(GO:0021984)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0060287 epithelial cilium movement(GO:0003351) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.2 GO:0051593 response to folic acid(GO:0051593)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.0 GO:0072010 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.0 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.4 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.3 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.5 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0050942 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.2 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:0010543 regulation of platelet activation(GO:0010543) negative regulation of platelet activation(GO:0010544)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0090196 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.2 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0045056 transcytosis(GO:0045056)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.0 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 0.0 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081)
0.0 0.0 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0 0.0 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.4 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.0 GO:0043276 anoikis(GO:0043276)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.4 GO:0042552 myelination(GO:0042552)
0.0 0.0 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.0 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.0 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.0 GO:0042481 regulation of odontogenesis(GO:0042481)
0.0 0.0 GO:0071223 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.0 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.0 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.0 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.0 GO:0035058 nonmotile primary cilium assembly(GO:0035058)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.0 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.2 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.2 GO:0042133 neurotransmitter metabolic process(GO:0042133)
0.0 0.1 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.1 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.0 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0001739 sex chromatin(GO:0001739)
0.1 0.3 GO:0000801 central element(GO:0000801)
0.1 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0044462 external encapsulating structure part(GO:0044462)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.4 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 0.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.0 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.0 GO:0005827 polar microtubule(GO:0005827)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.2 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1 0.2 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.2 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0001848 complement binding(GO:0001848)
0.0 0.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0001846 opsonin binding(GO:0001846)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0 0.0 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.0 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.3 GO:0019894 kinesin binding(GO:0019894)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.0 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.0 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.0 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.0 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0005536 glucose binding(GO:0005536)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.0 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.0 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.0 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 1.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.0 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.1 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.0 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.0 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins