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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HNF1A_HNF1B

Z-value: 0.64

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Transcription factors associated with HNF1A_HNF1B

Gene Symbol Gene ID Gene Info
HNF1A
ENSG00000135100.13 HNF1A
HNF1B
ENSG00000108753.8 HNF1B

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HNF1Bchr17_36102015_3610265226760.2451720.751.9e-02Click!
HNF1Bchr17_36102983_3610316819340.2873800.674.9e-02Click!
HNF1Bchr17_36102697_3610284822370.2664620.608.9e-02Click!
HNF1Bchr17_36104012_361041639220.4352700.541.3e-01Click!
HNF1Bchr17_36104676_361048272580.6816430.442.3e-01Click!

Activity of the HNF1A_HNF1B motif across conditions

Conditions sorted by the z-value of the HNF1A_HNF1B motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_85768780_85768931 0.51 ALX1
 ALX homeobox 1
 94970
 0.09
chr18_20739662_20739813 0.49 CABLES1
 Cdk5 and Abl enzyme substrate 1
 3948
 0.25
chr1_200865204_200865355 0.48 C1orf106
 chromosome 1 open reading frame 106
 1330
 0.42
chr5_101774760_101774911 0.47 SLCO6A1
 solute carrier organic anion transporter family, member 6A1
 59782
 0.13
chr2_133174054_133174205 0.47 GPR39
 G protein-coupled receptor 39
 18
 0.98
chr10_11602391_11602542 0.38 USP6NL
 USP6 N-terminal like
 13270
 0.25
chr6_12364096_12364247 0.35 ENSG00000223321
 .
 42842
 0.19
chr11_16946345_16946496 0.34 PLEKHA7
 pleckstrin homology domain containing, family A member 7
 43515
 0.12
chr1_211688650_211688892 0.33 RD3
 retinal degeneration 3
 22512
 0.2
chr18_21458592_21458743 0.31 LAMA3
 laminin, alpha 3
 5658
 0.23
chr3_111452039_111452190 0.30 PHLDB2
 pleckstrin homology-like domain, family B, member 2
 770
 0.71
chr3_183947999_183948171 0.29 VWA5B2
 von Willebrand factor A domain containing 5B2
 132
 0.92
chr10_46010179_46010570 0.27 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
 20445
 0.22
chr1_97344163_97344314 0.26 ENSG00000212039
 .
 24017
 0.23
chr17_37895484_37895662 0.26 GRB7
 growth factor receptor-bound protein 7
 549
 0.64
chr12_107991801_107991952 0.25 BTBD11
 BTB (POZ) domain containing 11
 17449
 0.18
chr2_234601388_234601539 0.25 UGT1A6
 UDP glucuronosyltransferase 1 family, polypeptide A6
 49
 0.95
chr3_47822404_47822881 0.24 SMARCC1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
 765
 0.62
chr3_33138761_33138999 0.24 GLB1
 galactosidase, beta 1
 158
 0.84
chr10_120966033_120966362 0.24 GRK5
 G protein-coupled receptor kinase 5
 904
 0.45
chr22_25508803_25509083 0.24 CTA-221G9.11
284
 0.93
chr1_207204103_207204254 0.24 C1orf116
 chromosome 1 open reading frame 116
 1914
 0.24
chr14_61188910_61189596 0.24 SIX4
 SIX homeobox 4
 1599
 0.41
chr8_118959706_118959909 0.23 EXT1
 exostosin glycosyltransferase 1
 162846
 0.04
chr13_77466816_77466967 0.23 KCTD12
 potassium channel tetramerization domain containing 12
 6351
 0.21
chr9_20320242_20320393 0.22 ENSG00000221744
 .
 25315
 0.21
chr19_12722754_12723067 0.22 ZNF791
 zinc finger protein 791
 1142
 0.25
chr4_75818567_75818718 0.22 PARM1
 prostate androgen-regulated mucin-like protein 1
 39663
 0.18
chr11_2405249_2405453 0.22 CD81
 CD81 molecule
 529
 0.65
chr10_29924729_29924934 0.20 SVIL
 supervillin
 930
 0.62
chr1_246324865_246325016 0.20 ENSG00000202184
 .
 27480
 0.18
chr9_74909575_74909726 0.19 ENSG00000252428
 .
 5104
 0.28
chr14_58748738_58749043 0.19 RP11-349A22.5
4851
 0.12
chr1_6420005_6420156 0.19 ACOT7
 acyl-CoA thioesterase 7
 676
 0.64
chr18_9648789_9648940 0.18 ENSG00000212572
 .
 30794
 0.14
chr4_181237914_181238065 0.18 NA
 NA
 > 106
 NA
chr3_77047404_77047555 0.18 ROBO2
 roundabout, axon guidance receptor, homolog 2 (Drosophila)
 41558
 0.21
chr6_24926936_24927087 0.18 FAM65B
 family with sequence similarity 65, member B
 9177
 0.23
chr17_47084887_47085038 0.18 RP11-501C14.6
6125
 0.1
chr11_14375529_14375805 0.17 RRAS2
 related RAS viral (r-ras) oncogene homolog 2
 379
 0.91
chr1_198610531_198610895 0.17 PTPRC
 protein tyrosine phosphatase, receptor type, C
 2421
 0.36
chr5_112503635_112503786 0.17 MCC
 mutated in colorectal cancers
 66664
 0.13
chr11_16761078_16761311 0.17 C11orf58
 chromosome 11 open reading frame 58
 989
 0.65
chr6_169720130_169720281 0.17 THBS2
 thrombospondin 2
 66066
 0.13
chr1_242400535_242400686 0.17 RP11-561I11.3
33753
 0.18
chr6_69869443_69869594 0.17 ENSG00000265498
 .
 55184
 0.16
chr1_192776419_192777001 0.16 RGS2
 regulator of G-protein signaling 2, 24kDa
 1461
 0.52
chr22_38578075_38578268 0.16 PLA2G6
 phospholipase A2, group VI (cytosolic, calcium-independent)
 334
 0.84
chr6_10310725_10311140 0.16 ENSG00000221583
 .
 88663
 0.07
chr8_49322264_49322415 0.16 ENSG00000252710
 .
 101749
 0.08
chr10_29932434_29932585 0.16 SVIL
 supervillin
 8608
 0.22
chr10_91092076_91093023 0.16 IFIT3
 interferon-induced protein with tetratricopeptide repeats 3
 308
 0.86
chr19_31210066_31211017 0.16 ENSG00000223148
 .
 105414
 0.08
chr13_44310211_44310362 0.16 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 50758
 0.18
chr13_98859522_98859872 0.16 ENSG00000263399
 .
 1081
 0.44
chr12_63025061_63025357 0.16 ENSG00000238475
 .
 19746
 0.14
chr2_216003041_216003192 0.16 ABCA12
 ATP-binding cassette, sub-family A (ABC1), member 12
 11
 0.99
chr1_8156287_8156493 0.15 ERRFI1
 ERBB receptor feedback inhibitor 1
 70022
 0.1
chrX_98993158_98993309 0.15 ENSG00000252430
 .
 352959
 0.01
chr22_47023615_47023766 0.15 GRAMD4
 GRAM domain containing 4
 1032
 0.62
chr4_57302350_57302924 0.15 PAICS
 phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
 319
 0.75
chr15_60883034_60883482 0.15 RORA
 RAR-related orphan receptor A
 1482
 0.47
chr3_121450033_121450184 0.15 GOLGB1
 golgin B1
 1311
 0.47
chr19_6464115_6464545 0.15 CRB3
 crumbs homolog 3 (Drosophila)
 36
 0.92
chr8_49621928_49622079 0.15 EFCAB1
 EF-hand calcium binding domain 1
 20345
 0.28
chr10_5490099_5490572 0.15 NET1
 neuroepithelial cell transforming 1
 1761
 0.33
chr8_76319339_76319966 0.15 HNF4G
 hepatocyte nuclear factor 4, gamma
 619
 0.85
chr6_74512871_74513022 0.15 RP11-553A21.3
107092
 0.06
chr11_134145279_134145568 0.15 GLB1L3
 galactosidase, beta 1-like 3
 1212
 0.41
chr12_116192167_116192318 0.15 ENSG00000240205
 .
 36712
 0.21
chr7_139047352_139047690 0.15 C7orf55-LUC7L2
 C7orf55-LUC7L2 readthrough
 2867
 0.19
chr11_99364685_99364836 0.15 CNTN5
 contactin 5
 62110
 0.14
chr4_113331922_113332073 0.14 RP11-402J6.1
104544
 0.06
chr2_177515764_177515915 0.14 ENSG00000252027
 .
 13565
 0.29
chr4_106634812_106634963 0.14 GSTCD
 glutathione S-transferase, C-terminal domain containing
 2884
 0.28
chr6_137582969_137583120 0.14 IFNGR1
 interferon gamma receptor 1
 42458
 0.19
chr3_120397291_120397574 0.14 HGD
 homogentisate 1,2-dioxygenase
 3528
 0.29
chr11_9272154_9272305 0.14 RP11-5L12.1
5173
 0.21
chr6_16595154_16595305 0.14 RP1-151F17.1
166140
 0.04
chr13_64460857_64461008 0.14 ENSG00000202478
 .
 102998
 0.08
chr10_81841980_81842261 0.14 TMEM254
 transmembrane protein 254
 641
 0.7
chr14_65170645_65170998 0.14 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 1
 0.98
chr2_61112921_61113072 0.14 REL
 v-rel avian reticuloendotheliosis viral oncogene homolog
 4205
 0.23
chr6_2952235_2952386 0.14 SERPINB6
 serpin peptidase inhibitor, clade B (ovalbumin), member 6
 9251
 0.16
chr6_147379941_147380092 0.14 STXBP5-AS1
 STXBP5 antisense RNA 1
 60583
 0.16
chr8_119669828_119669979 0.14 SAMD12
 sterile alpha motif domain containing 12
 35669
 0.24
chr18_27841796_27841947 0.13 ENSG00000251702
 .
 722201
 0.0
chr2_51447556_51447707 0.13 NRXN1
 neurexin 1
 187957
 0.03
chr1_207413756_207413907 0.13 CD55
 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 81022
 0.09
chr12_76271082_76271233 0.13 ENSG00000243420
 .
 80753
 0.1
chr16_20774903_20775254 0.13 ACSM3
 acyl-CoA synthetase medium-chain family member 3
 54
 0.96
chr12_122519567_122519958 0.13 MLXIP
 MLX interacting protein
 3134
 0.29
chr10_71529381_71529532 0.13 COL13A1
 collagen, type XIII, alpha 1
 32188
 0.17
chr2_115486319_115486470 0.13 DPP10-AS3
 DPP10 antisense RNA 3
 104731
 0.08
chr9_1232780_1232931 0.13 ENSG00000202383
 .
 100982
 0.08
chr21_27936458_27936609 0.13 CYYR1
 cysteine/tyrosine-rich 1
 8962
 0.3
chrX_57931578_57932092 0.13 ZXDA
 zinc finger, X-linked, duplicated A
 5232
 0.36
chr14_21511304_21511455 0.13 RNASE7
 ribonuclease, RNase A family, 7
 994
 0.3
chr5_67576888_67577103 0.13 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 860
 0.74
chrX_105065279_105065430 0.13 NRK
 Nik related kinase
 1182
 0.6
chr3_1166731_1166882 0.13 CNTN6
 contactin 6
 32461
 0.22
chr6_100722020_100722171 0.13 RP1-121G13.2
152899
 0.04
chr8_133328849_133329000 0.13 KCNQ3
 potassium voltage-gated channel, KQT-like subfamily, member 3
 130585
 0.05
chr5_95615743_95615894 0.12 ENSG00000206997
 .
 69887
 0.12
chr7_22861355_22861506 0.12 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
 533
 0.81
chrX_135436156_135436307 0.12 GPR112
 G protein-coupled receptor 112
 48051
 0.14
chr5_23013590_23013917 0.12 CDH12
 cadherin 12, type 2 (N-cadherin 2)
 160022
 0.04
chr1_153585227_153585451 0.12 S100A16
 S100 calcium binding protein A16
 220
 0.83
chr18_61220889_61221040 0.12 SERPINB12
 serpin peptidase inhibitor, clade B (ovalbumin), member 12
 2429
 0.28
chrX_131405137_131405331 0.12 RAP2C
 RAP2C, member of RAS oncogene family
 51773
 0.14
chr6_144585691_144586280 0.12 UTRN
 utrophin
 20852
 0.24
chr6_118638895_118639096 0.12 PLN
 phospholamban
 230466
 0.02
chr4_124571165_124571642 0.12 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 250280
 0.02
chr3_128892694_128892845 0.12 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 9973
 0.13
chr4_182964416_182964567 0.12 AC108142.1
41746
 0.18
chr18_13019627_13019778 0.12 CEP192
 centrosomal protein 192kDa
 10084
 0.21
chr8_142289533_142290316 0.12 RP11-10J21.3
 Uncharacterized protein
 25260
 0.12
chr2_102466743_102466894 0.12 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 5621
 0.28
chr2_206678700_206678851 0.11 AC007362.3
50045
 0.15
chr8_42356526_42357223 0.11 SLC20A2
 solute carrier family 20 (phosphate transporter), member 2
 1887
 0.34
chr18_29033854_29034005 0.11 DSG3
 desmoglein 3
 6171
 0.18
chr17_70583135_70583286 0.11 ENSG00000200783
 .
 77081
 0.11
chr5_67564084_67564251 0.11 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 11901
 0.28
chr2_184151507_184151754 0.11 NUP35
 nucleoporin 35kDa
 162457
 0.04
chr18_4269017_4269168 0.11 DLGAP1-AS5
 DLGAP1 antisense RNA 5
 4459
 0.35
chr17_12887644_12888019 0.11 ARHGAP44
 Rho GTPase activating protein 44
 4406
 0.18
chr15_93428286_93428633 0.11 CHD2
 chromodomain helicase DNA binding protein 2
 1933
 0.32
chr2_182168845_182168996 0.11 ENSG00000266705
 .
 1459
 0.58
chr9_79502275_79502437 0.11 PRUNE2
 prune homolog 2 (Drosophila)
 18645
 0.27
chr17_48800568_48800788 0.11 LUC7L3
 LUC7-like 3 (S. cerevisiae)
 3670
 0.16
chr2_44518711_44518931 0.11 SLC3A1
 solute carrier family 3 (amino acid transporter heavy chain), member 1
 6187
 0.21
chr6_55730770_55730921 0.11 BMP5
 bone morphogenetic protein 5
 8832
 0.33
chr6_144809166_144809317 0.11 UTRN
 utrophin
 95105
 0.09
chr6_109581664_109581815 0.11 ENSG00000238474
 .
 30822
 0.16
chr10_116285976_116286984 0.10 ABLIM1
 actin binding LIM protein 1
 114
 0.98
chr1_28696522_28697055 0.10 PHACTR4
 phosphatase and actin regulator 4
 674
 0.67
chr7_47071998_47072149 0.10 TNS3
 tensin 3
 247843
 0.02
chr6_136760831_136760982 0.10 MAP7
 microtubule-associated protein 7
 27107
 0.21
chr11_69969718_69969869 0.10 RP11-805J14.3
5610
 0.17
chr12_62657622_62657800 0.10 USP15
 ubiquitin specific peptidase 15
 3502
 0.25
chr13_97910664_97910819 0.10 MBNL2
 muscleblind-like splicing regulator 2
 17717
 0.27
chr2_117398214_117398365 0.10 ENSG00000239185
 .
 499062
 0.0
chr6_142698058_142698209 0.10 GPR126
 G protein-coupled receptor 126
 13316
 0.29
chr5_154145914_154146065 0.10 LARP1
 La ribonucleoprotein domain family, member 1
 9255
 0.18
chr18_59208775_59208926 0.10 CDH20
 cadherin 20, type 2
 8249
 0.32
chr3_142682580_142682815 0.10 RP11-372E1.6
203
 0.7
chr4_43019583_43019734 0.10 GRXCR1
 glutaredoxin, cysteine rich 1
 124374
 0.06
chr3_171918528_171919229 0.10 ENSG00000243398
 .
 36238
 0.18
chr12_68715253_68715404 0.10 MDM1
 Mdm1 nuclear protein homolog (mouse)
 10488
 0.26
chr6_10082497_10082648 0.10 OFCC1
 orofacial cleft 1 candidate 1
 32435
 0.24
chr17_56490822_56490973 0.10 RNF43
 ring finger protein 43
 2105
 0.25
chr9_7515477_7515628 0.10 TMEM261
 transmembrane protein 261
 284515
 0.01
chr7_55055085_55055236 0.10 EGFR
 epidermal growth factor receptor
 31554
 0.23
chr17_81047529_81047808 0.10 METRNL
 meteorin, glial cell differentiation regulator-like
 4326
 0.27
chr6_116381607_116382020 0.10 FRK
 fyn-related kinase
 108
 0.97
chr10_102650198_102650475 0.10 ENSG00000222072
 .
 16701
 0.13
chr12_27262305_27262456 0.10 C12orf71
 chromosome 12 open reading frame 71
 26933
 0.19
chr12_46757806_46758524 0.10 SLC38A2
 solute carrier family 38, member 2
 925
 0.64
chr3_107317640_107318380 0.10 BBX
 bobby sox homolog (Drosophila)
 150
 0.98
chr10_71712113_71712264 0.10 COL13A1
 collagen, type XIII, alpha 1
 21979
 0.22
chr17_71306920_71307184 0.10 CDC42EP4
 CDC42 effector protein (Rho GTPase binding) 4
 495
 0.81
chr1_198418768_198418919 0.10 ATP6V1G3
 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
 90961
 0.09
chr4_99849016_99849252 0.09 RP11-571L19.7
914
 0.37
chr3_141597606_141597757 0.09 ATP1B3
 ATPase, Na+/K+ transporting, beta 3 polypeptide
 1310
 0.45
chr15_34974520_34974671 0.09 GJD2
 gap junction protein, delta 2, 36kDa
 72571
 0.08
chr15_90543812_90544634 0.09 ZNF710
 zinc finger protein 710
 401
 0.81
chr5_52546058_52546209 0.09 MOCS2
 molybdenum cofactor synthesis 2
 140240
 0.04
chr17_62287879_62288139 0.09 TEX2
 testis expressed 2
 2070
 0.34
chr8_92210223_92210374 0.09 ENSG00000266194
 .
 7415
 0.2
chr5_14205024_14205555 0.09 TRIO
 trio Rho guanine nucleotide exchange factor
 21382
 0.29
chr15_51317270_51317421 0.09 RP11-394B5.2
44438
 0.16
chr16_88007697_88007848 0.09 BANP
 BTG3 associated nuclear protein
 4148
 0.26
chr8_41181710_41181861 0.09 SFRP1
 secreted frizzled-related protein 1
 14769
 0.17
chr10_14606601_14606845 0.09 FAM107B
 family with sequence similarity 107, member B
 7306
 0.26
chr7_148724822_148725626 0.09 PDIA4
 protein disulfide isomerase family A, member 4
 336
 0.84
chrX_127442791_127442942 0.09 ACTRT1
 actin-related protein T1
 256484
 0.02
chr5_34687146_34687427 0.09 RAI14
 retinoic acid induced 14
 378
 0.9
chr1_68214173_68214559 0.09 ENSG00000238778
 .
 23970
 0.19
chr9_135548642_135548835 0.09 DDX31
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
 2950
 0.25
chr16_66541951_66542102 0.09 TK2
 thymidine kinase 2, mitochondrial
 5660
 0.12
chr21_42441242_42441393 0.09 LINC00323
 long intergenic non-protein coding RNA 323
 78033
 0.09
chr1_222440358_222440509 0.08 ENSG00000222399
 .
 236644
 0.02
chr13_49081946_49082097 0.08 RCBTB2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
 25192
 0.23
chr10_121412015_121412434 0.08 BAG3
 BCL2-associated athanogene 3
 1342
 0.5
chr3_175025439_175025620 0.08 NAALADL2-AS2
 NAALADL2 antisense RNA 2
 36644
 0.19
chr3_161089901_161090298 0.08 SPTSSB
 serine palmitoyltransferase, small subunit B
 569
 0.86
chr15_71006570_71006722 0.08 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 11032
 0.26
chr2_165776815_165776966 0.08 SLC38A11
 solute carrier family 38, member 11
 17043
 0.17
chr1_33447039_33447276 0.08 RP1-117O3.2
5519
 0.15
chrX_133523066_133523217 0.08 ENSG00000251962
 .
 14271
 0.17
chrX_119678777_119678928 0.08 ENSG00000272179
 .
 682
 0.7
chr18_63063126_63063277 0.08 CDH7
 cadherin 7, type 2
 354287
 0.01
chr15_94782960_94783136 0.08 MCTP2
 multiple C2 domains, transmembrane 2
 8281
 0.33
chr3_190313233_190313384 0.08 IL1RAP
 interleukin 1 receptor accessory protein
 19789
 0.23
chr18_12255048_12255199 0.08 CIDEA
 cell death-inducing DFFA-like effector a
 805
 0.66
chr18_29952348_29952499 0.08 RP11-344B2.2
85023
 0.08
chr1_244212846_244213916 0.08 ZBTB18
 zinc finger and BTB domain containing 18
 1204
 0.52
chr2_113538908_113539059 0.08 IL1A
 interleukin 1, alpha
 3184
 0.22
chr18_26683920_26684071 0.08 ENSG00000265730
 .
 8352
 0.28
chr19_4970283_4970930 0.08 KDM4B
 lysine (K)-specific demethylase 4B
 1463
 0.39

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HNF1A_HNF1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.1 GO:0032049 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.0 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0031274 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0060539 diaphragm development(GO:0060539)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.0 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.0 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.0 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling