Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HOXA1

Z-value: 1.77

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Transcription factors associated with HOXA1

Gene Symbol Gene ID Gene Info
HOXA1
ENSG00000105991.7 HOXA1

Activity of the HOXA1 motif across conditions

Conditions sorted by the z-value of the HOXA1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_104152667_104152938 0.77 BAALC
 brain and acute leukemia, cytoplasmic
 136
 0.88
chr2_27301899_27302732 0.72 EMILIN1
 elastin microfibril interfacer 1
 880
 0.32
chr3_87036535_87037613 0.71 VGLL3
 vestigial like 3 (Drosophila)
 2778
 0.42
chr9_18474095_18474958 0.68 ADAMTSL1
 ADAMTS-like 1
 295
 0.95
chr15_95869891_95870263 0.61 ENSG00000222076
 .
 418956
 0.01
chr7_100773540_100774051 0.57 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 3416
 0.13
chr2_223917925_223918130 0.55 KCNE4
 potassium voltage-gated channel, Isk-related family, member 4
 1165
 0.62
chr11_27739578_27739815 0.55 BDNF
 brain-derived neurotrophic factor
 1598
 0.49
chr1_15273698_15273906 0.55 KAZN
 kazrin, periplakin interacting protein
 1387
 0.59
chr6_121756849_121757212 0.53 GJA1
 gap junction protein, alpha 1, 43kDa
 192
 0.94
chr5_15501266_15501663 0.50 FBXL7
 F-box and leucine-rich repeat protein 7
 83
 0.99
chr15_67229196_67229347 0.50 SMAD3
 SMAD family member 3
 126830
 0.05
chr18_53068422_53068903 0.50 TCF4
 transcription factor 4
 96
 0.98
chr3_61549164_61549336 0.48 PTPRG
 protein tyrosine phosphatase, receptor type, G
 1665
 0.55
chr5_54456456_54456818 0.48 GPX8
 glutathione peroxidase 8 (putative)
 639
 0.58
chr11_33755519_33755851 0.47 CD59
 CD59 molecule, complement regulatory protein
 2269
 0.24
chr6_121757423_121758012 0.46 GJA1
 gap junction protein, alpha 1, 43kDa
 879
 0.59
chr17_36623721_36623872 0.45 ARHGAP23
 Rho GTPase activating protein 23
 4384
 0.19
chr10_33620428_33620906 0.45 NRP1
 neuropilin 1
 2643
 0.37
chr13_39991746_39991969 0.45 ENSG00000238408
 .
 29496
 0.24
chr12_123215443_123215626 0.45 HCAR1
 hydroxycarboxylic acid receptor 1
 144
 0.94
chr11_126870217_126870446 0.45 KIRREL3
 kin of IRRE like 3 (Drosophila)
 85
 0.96
chr4_108746841_108747185 0.45 SGMS2
 sphingomyelin synthase 2
 649
 0.76
chr13_93880944_93881123 0.44 GPC6
 glypican 6
 1938
 0.5
chr8_89337580_89337731 0.42 RP11-586K2.1
1410
 0.42
chr11_119209203_119209543 0.42 RP11-334E6.10
1354
 0.21
chr1_32169073_32169273 0.41 COL16A1
 collagen, type XVI, alpha 1
 595
 0.68
chr6_165722551_165723097 0.41 C6orf118
 chromosome 6 open reading frame 118
 272
 0.95
chr3_157156849_157157000 0.41 PTX3
 pentraxin 3, long
 2346
 0.38
chr1_68696648_68696887 0.41 WLS
 wntless Wnt ligand secretion mediator
 603
 0.8
chr6_35286420_35286751 0.41 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 9070
 0.18
chr18_57326676_57327097 0.41 CCBE1
 collagen and calcium binding EGF domains 1
 6508
 0.21
chr12_110547355_110547534 0.41 IFT81
 intraflagellar transport 81 homolog (Chlamydomonas)
 14696
 0.2
chr6_166421798_166421999 0.41 ENSG00000252196
 .
 66069
 0.12
chr4_81189966_81190509 0.40 FGF5
 fibroblast growth factor 5
 2444
 0.36
chr13_111049575_111050268 0.40 ENSG00000238629
 .
 16631
 0.22
chr6_132269903_132270239 0.40 RP11-69I8.3
2015
 0.32
chr3_25470884_25471099 0.40 RARB
 retinoic acid receptor, beta
 1189
 0.61
chr10_78307456_78307607 0.39 RP11-325D15.2
13221
 0.29
chr4_41215270_41215769 0.39 APBB2
 amyloid beta (A4) precursor protein-binding, family B, member 2
 956
 0.59
chr6_72596608_72597181 0.39 RIMS1
 regulating synaptic membrane exocytosis 1
 167
 0.98
chr4_69138068_69138418 0.38 TMPRSS11B
 transmembrane protease, serine 11B
 26805
 0.16
chr2_19807945_19808132 0.38 OSR1
 odd-skipped related transciption factor 1
 249624
 0.02
chr11_19735220_19735722 0.38 NAV2
 neuron navigator 2
 328
 0.92
chr15_56206351_56206878 0.38 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
 1238
 0.55
chr10_79396627_79397649 0.38 KCNMA1
 potassium large conductance calcium-activated channel, subfamily M, alpha member 1
 67
 0.98
chr20_43344352_43344524 0.38 WISP2
 WNT1 inducible signaling pathway protein 2
 552
 0.7
chr1_230993206_230993358 0.38 C1orf198
 chromosome 1 open reading frame 198
 1500
 0.31
chr6_35285702_35286007 0.37 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 8339
 0.18
chr12_15490350_15490501 0.37 RERG
 RAS-like, estrogen-regulated, growth inhibitor
 11107
 0.24
chr6_39761310_39761623 0.36 DAAM2
 dishevelled associated activator of morphogenesis 2
 672
 0.79
chr3_66139685_66140118 0.36 SLC25A26
 solute carrier family 25 (S-adenosylmethionine carrier), member 26
 20616
 0.25
chr9_98900086_98900237 0.36 ENSG00000201938
 .
 34705
 0.19
chr13_31421923_31422100 0.36 MEDAG
 mesenteric estrogen-dependent adipogenesis
 58317
 0.12
chr8_98306353_98306552 0.36 TSPYL5
 TSPY-like 5
 16276
 0.25
chr2_75274937_75275088 0.36 ENSG00000263909
 .
 42927
 0.17
chr1_170638728_170639131 0.36 PRRX1
 paired related homeobox 1
 5851
 0.31
chr5_83678519_83678875 0.36 EDIL3
 EGF-like repeats and discoidin I-like domains 3
 1507
 0.37
chr8_40011056_40011215 0.36 C8orf4
 chromosome 8 open reading frame 4
 146
 0.98
chr17_65524710_65524896 0.35 CTD-2653B5.1
4206
 0.24
chrX_34673939_34674563 0.35 TMEM47
 transmembrane protein 47
 1154
 0.68
chr6_166525902_166526091 0.35 ENSG00000231297
 .
 12655
 0.24
chr4_4862278_4863048 0.35 MSX1
 msh homeobox 1
 1270
 0.58
chr4_114899856_114900283 0.35 ARSJ
 arylsulfatase family, member J
 83
 0.98
chr15_56115551_56115702 0.34 ENSG00000221218
 .
 62326
 0.12
chr15_56208525_56208789 0.34 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
 649
 0.78
chr5_55193656_55194061 0.34 AC008914.1
 Uncharacterized protein
 30711
 0.14
chr1_234757591_234757803 0.34 IRF2BP2
 interferon regulatory factor 2 binding protein 2
 12426
 0.19
chr2_200308390_200308562 0.34 SATB2
 SATB homeobox 2
 12335
 0.23
chr5_38847067_38847228 0.34 OSMR
 oncostatin M receptor
 1046
 0.65
chr7_101813412_101813679 0.34 ENSG00000252824
 .
 23899
 0.18
chr16_21199797_21200120 0.34 AF001550.7
6210
 0.15
chr17_79317268_79317735 0.33 TMEM105
 transmembrane protein 105
 13027
 0.13
chr1_32042837_32043215 0.33 TINAGL1
 tubulointerstitial nephritis antigen-like 1
 887
 0.47
chr2_30888986_30889287 0.33 CAPN13
 calpain 13
 141175
 0.05
chr16_65566073_65566543 0.33 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 410040
 0.01
chr3_71552874_71553148 0.33 ENSG00000221264
 .
 38229
 0.17
chr8_89338891_89339093 0.33 RP11-586K2.1
73
 0.93
chr15_42749459_42749764 0.33 ZNF106
 zinc finger protein 106
 100
 0.96
chr15_100654971_100655259 0.33 ADAMTS17
 ADAM metallopeptidase with thrombospondin type 1 motif, 17
 5803
 0.21
chr1_17006681_17006859 0.33 ENSG00000264742
 .
 980
 0.43
chr15_60688524_60688675 0.33 ANXA2
 annexin A2
 938
 0.68
chr4_77674194_77674345 0.33 RP11-359D14.2
5358
 0.25
chr22_47732716_47732867 0.32 LL22NC03-75H12.2
 Novel protein; Uncharacterized protein
 150069
 0.05
chr4_66536630_66536781 0.32 EPHA5
 EPH receptor A5
 492
 0.89
chr5_172752767_172752937 0.32 STC2
 stanniocalcin 2
 948
 0.57
chr19_13137030_13137181 0.32 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 1294
 0.28
chr1_231002889_231003524 0.32 C1orf198
 chromosome 1 open reading frame 198
 1193
 0.37
chr4_121991394_121991545 0.32 NDNF
 neuron-derived neurotrophic factor
 1687
 0.41
chr1_209381259_209381734 0.32 ENSG00000230937
 .
 223982
 0.02
chr4_66534785_66535387 0.32 EPHA5
 EPH receptor A5
 567
 0.87
chr3_145878260_145878775 0.32 PLOD2
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
 262
 0.94
chr16_86604206_86604444 0.32 RP11-463O9.5
2958
 0.2
chr17_42185327_42185524 0.32 HDAC5
 histone deacetylase 5
 3284
 0.12
chr1_51730484_51730663 0.32 RP11-296A18.6
1173
 0.41
chr5_71920587_71920821 0.31 ZNF366
 zinc finger protein 366
 117150
 0.06
chr19_49661333_49661989 0.31 TRPM4
 transient receptor potential cation channel, subfamily M, member 4
 562
 0.58
chr13_45149393_45149691 0.31 TSC22D1
 TSC22 domain family, member 1
 850
 0.72
chr5_148788074_148788225 0.31 ENSG00000208035
 .
 20332
 0.11
chr16_73178105_73178293 0.31 C16orf47
 chromosome 16 open reading frame 47
 147
 0.98
chr20_30299190_30299341 0.31 AL160175.1
9736
 0.13
chr1_16874265_16874567 0.31 ENSG00000266584
 .
 993
 0.42
chr4_134070427_134071051 0.31 PCDH10
 protocadherin 10
 269
 0.96
chr2_227661377_227661773 0.31 IRS1
 insulin receptor substrate 1
 2900
 0.28
chr5_141980009_141980160 0.30 AC005592.2
18671
 0.18
chr2_238321225_238321570 0.30 COL6A3
 collagen, type VI, alpha 3
 1394
 0.45
chr21_47519816_47520002 0.30 COL6A2
 collagen, type VI, alpha 2
 1198
 0.37
chr12_119617594_119617745 0.30 HSPB8
 heat shock 22kDa protein 8
 274
 0.89
chr22_27152907_27153066 0.30 CRYBA4
 crystallin, beta A4
 135058
 0.05
chr5_72247720_72248016 0.30 FCHO2
 FCH domain only 2
 3940
 0.27
chr1_162601208_162601447 0.30 DDR2
 discoidin domain receptor tyrosine kinase 2
 164
 0.96
chr13_59686261_59686462 0.29 ENSG00000239003
 .
 367843
 0.01
chr5_31993644_31993795 0.29 ENSG00000266243
 .
 57454
 0.12
chr12_75728365_75728595 0.29 GLIPR1L1
 GLI pathogenesis-related 1 like 1
 17
 0.98
chr12_118626563_118627015 0.29 TAOK3
 TAO kinase 3
 1538
 0.42
chr7_116312981_116313724 0.29 MET
 met proto-oncogene
 893
 0.68
chr1_65363518_65363760 0.29 JAK1
 Janus kinase 1
 68548
 0.12
chr8_42072731_42073079 0.29 PLAT
 plasminogen activator, tissue
 7663
 0.16
chr15_38545463_38545840 0.29 SPRED1
 sprouty-related, EVH1 domain containing 1
 269
 0.96
chr4_189203647_189204041 0.29 RP11-366H4.3
139311
 0.05
chr13_97767408_97767587 0.29 ENSG00000238522
 .
 57864
 0.14
chr3_25470006_25470271 0.29 RARB
 retinoic acid receptor, beta
 336
 0.93
chr8_25793197_25793466 0.29 EBF2
 early B-cell factor 2
 47899
 0.19
chr1_17186360_17186577 0.29 ENSG00000263811
 .
 952
 0.5
chr12_26306644_26306883 0.29 SSPN
 sarcospan
 18863
 0.17
chr14_53416235_53416562 0.29 FERMT2
 fermitin family member 2
 888
 0.69
chr5_156975981_156976178 0.29 AC106801.1
16893
 0.15
chr8_50822371_50822736 0.29 SNTG1
 syntrophin, gamma 1
 204
 0.97
chr2_135130087_135130255 0.29 MGAT5
 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
 118341
 0.06
chr3_57184582_57184733 0.29 IL17RD
 interleukin 17 receptor D
 8123
 0.2
chr18_33935213_33935397 0.29 FHOD3
 formin homology 2 domain containing 3
 57506
 0.15
chr8_105429971_105430182 0.29 ENSG00000222158
 .
 7511
 0.18
chr10_4850634_4850785 0.28 AKR1E2
 aldo-keto reductase family 1, member E2
 17737
 0.24
chr19_55796807_55796987 0.28 BRSK1
 BR serine/threonine kinase 1
 1108
 0.27
chr13_108373924_108374075 0.28 ENSG00000221473
 .
 85620
 0.1
chr6_10555958_10556148 0.28 GCNT2
 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
 187
 0.95
chr12_78334342_78334902 0.28 NAV3
 neuron navigator 3
 25434
 0.27
chr4_79567611_79567882 0.28 ENSG00000238816
 .
 6492
 0.23
chr6_167116303_167116499 0.28 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 54998
 0.15
chr16_4366907_4367444 0.28 GLIS2
 GLIS family zinc finger 2
 2413
 0.21
chr11_106239153_106239583 0.28 RP11-680E19.1
104326
 0.08
chr6_137442626_137442884 0.28 IL22RA2
 interleukin 22 receptor, alpha 2
 52030
 0.14
chr10_35105469_35105702 0.28 PARD3-AS1
 PARD3 antisense RNA 1
 890
 0.52
chr15_75628715_75629138 0.28 COMMD4
 COMM domain containing 4
 480
 0.69
chr18_21562271_21562511 0.28 TTC39C
 tetratricopeptide repeat domain 39C
 10346
 0.18
chr19_41726166_41726324 0.28 AXL
 AXL receptor tyrosine kinase
 1105
 0.33
chr1_65005729_65006114 0.28 ENSG00000264470
 .
 39609
 0.19
chr10_14051003_14051266 0.28 FRMD4A
 FERM domain containing 4A
 602
 0.78
chr1_150481112_150481644 0.28 ECM1
 extracellular matrix protein 1
 795
 0.48
chr12_77257769_77258091 0.28 RP11-461F16.3
14043
 0.22
chr6_152701268_152701555 0.28 SYNE1-AS1
 SYNE1 antisense RNA 1
 270
 0.91
chr2_105461225_105461520 0.28 LINC01158
 long intergenic non-protein coding RNA 1158
 6539
 0.15
chr3_155394177_155394568 0.28 PLCH1
 phospholipase C, eta 1
 167
 0.97
chr20_56283014_56283182 0.27 PMEPA1
 prostate transmembrane protein, androgen induced 1
 1718
 0.47
chr15_69941076_69941227 0.27 ENSG00000238870
 .
 82010
 0.09
chr6_45523951_45524153 0.27 ENSG00000252738
 .
 89789
 0.09
chr3_114342653_114342865 0.27 ZBTB20
 zinc finger and BTB domain containing 20
 294
 0.95
chr13_37492943_37493377 0.27 SMAD9
 SMAD family member 9
 1215
 0.52
chr12_13025379_13025989 0.27 GPRC5A
 G protein-coupled receptor, family C, group 5, member A
 18032
 0.14
chr1_68640289_68640593 0.27 ENSG00000221203
 .
 8852
 0.22
chr5_39423074_39423254 0.27 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 1806
 0.48
chr14_73248118_73248269 0.27 ENSG00000206751
 .
 71846
 0.11
chr9_130854010_130854186 0.27 SLC25A25
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
 355
 0.73
chr7_22233477_22233744 0.27 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
 83
 0.98
chr16_58534463_58534728 0.27 NDRG4
 NDRG family member 4
 545
 0.68
chr1_200708839_200709372 0.27 CAMSAP2
 calmodulin regulated spectrin-associated protein family, member 2
 198
 0.96
chr8_54426719_54426874 0.27 OPRK1
 opioid receptor, kappa 1
 262539
 0.02
chr4_39622770_39622921 0.27 ENSG00000252796
 .
 213
 0.93
chr17_59657386_59657548 0.27 NACA2
 nascent polypeptide-associated complex alpha subunit 2
 11096
 0.25
chr1_31380173_31380807 0.26 SDC3
 syndecan 3
 1118
 0.44
chr3_55513844_55514078 0.26 WNT5A
 wingless-type MMTV integration site family, member 5A
 1263
 0.55
chr13_111451848_111452195 0.26 LINC00346
 long intergenic non-protein coding RNA 346
 70141
 0.09
chr16_69959056_69959289 0.26 WWP2
 WW domain containing E3 ubiquitin protein ligase 2
 279
 0.89
chr2_218866425_218866801 0.26 TNS1
 tensin 1
 1105
 0.51
chr6_121763906_121764104 0.26 GJA1
 gap junction protein, alpha 1, 43kDa
 7167
 0.19
chr1_165868486_165868637 0.26 RP11-525G13.2
1359
 0.44
chr7_137402579_137403024 0.26 DGKI
 diacylglycerol kinase, iota
 128481
 0.05
chr1_39881370_39881756 0.26 MACF1
 microtubule-actin crosslinking factor 1
 1491
 0.39
chr13_110957687_110957838 0.26 COL4A2
 collagen, type IV, alpha 2
 397
 0.84
chr11_131615004_131615247 0.26 NTM
 neurotrimin
 84237
 0.1
chr7_47497207_47497358 0.26 TNS3
 tensin 3
 4453
 0.36
chr3_159451541_159451741 0.26 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 29861
 0.17
chr1_163039219_163039545 0.26 RGS4
 regulator of G-protein signaling 4
 231
 0.96
chr9_73021285_73021445 0.26 KLF9
 Kruppel-like factor 9
 8175
 0.28
chr18_53214040_53214242 0.26 TCF4
 transcription factor 4
 36141
 0.18
chr10_49812568_49813319 0.26 ARHGAP22
 Rho GTPase activating protein 22
 54
 0.98
chr11_12306253_12306493 0.26 MICALCL
 MICAL C-terminal like
 2074
 0.3
chr12_115107097_115107743 0.26 ENSG00000199220
 .
 11553
 0.21
chr1_88150357_88150552 0.26 ENSG00000199318
 .
 231398
 0.02
chr6_169652381_169652976 0.26 THBS2
 thrombospondin 2
 432
 0.89
chr7_44922681_44922832 0.26 ENSG00000264326
 .
 1357
 0.26
chrX_86773122_86773424 0.26 KLHL4
 kelch-like family member 4
 456
 0.88
chr6_149333139_149333306 0.26 RP11-162J8.3
20487
 0.23
chr17_59479149_59479300 0.26 RP11-332H18.5
1620
 0.23
chr2_189842947_189843104 0.26 ENSG00000221502
 .
 207
 0.95
chr1_172110530_172111247 0.26 ENSG00000207949
 .
 2841
 0.22
chr9_133411049_133411413 0.25 FUBP3
 far upstream element (FUSE) binding protein 3
 43762
 0.14
chr15_80773163_80773372 0.25 RP11-210M15.1
35774
 0.14
chr3_11196334_11196700 0.25 HRH1
 histamine receptor H1
 303
 0.94
chr5_14265991_14266171 0.25 TRIO
 trio Rho guanine nucleotide exchange factor
 25005
 0.28

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HOXA1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 0.6 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.2 0.6 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.2 0.5 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.2 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.5 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.4 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.4 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.3 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.3 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.3 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.1 0.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.5 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.3 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.1 0.2 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:0036336 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.1 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.4 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.2 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.4 GO:0009629 response to gravity(GO:0009629)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.4 GO:0071320 cellular response to cAMP(GO:0071320)
0.1 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.4 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0090103 cochlea morphogenesis(GO:0090103)
0.0 0.3 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.2 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:0032347 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0060435 bronchiole development(GO:0060435)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.2 GO:0010955 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.1 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.3 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.5 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.1 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.1 GO:0001839 neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.6 GO:0048008 platelet-derived growth factor receptor signaling pathway(GO:0048008)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.2 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0060536 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0031223 response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.0 0.1 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.1 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:1903077 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.4 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.7 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.4 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.6 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.4 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0051150 regulation of smooth muscle cell differentiation(GO:0051150)
0.0 0.1 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.0 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0043084 penile erection(GO:0043084)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0033345 asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.2 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.0 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.0 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.1 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.0 GO:0060124 regulation of growth hormone secretion(GO:0060123) positive regulation of growth hormone secretion(GO:0060124)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.0 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.0 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 0.1 GO:0043277 apoptotic cell clearance(GO:0043277)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0010662 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.0 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.0 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:0032099 negative regulation of appetite(GO:0032099)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0050922 negative regulation of chemotaxis(GO:0050922)
0.0 0.1 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.3 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.0 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.0 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.0 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0030501 positive regulation of bone mineralization(GO:0030501)
0.0 0.0 GO:0019322 pentose biosynthetic process(GO:0019322)
0.0 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.0 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.1 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.0 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.1 GO:0033008 positive regulation of myeloid leukocyte mediated immunity(GO:0002888) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0051279 regulation of release of sequestered calcium ion into cytosol(GO:0051279)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.1 GO:0003151 outflow tract morphogenesis(GO:0003151)
0.0 0.3 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0003097 renal water transport(GO:0003097)
0.0 0.4 GO:0071773 BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.0 GO:0021955 central nervous system projection neuron axonogenesis(GO:0021952) central nervous system neuron axonogenesis(GO:0021955)
0.0 0.1 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0061316 canonical Wnt signaling pathway involved in heart development(GO:0061316)
0.0 0.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244)
0.0 0.1 GO:0050807 regulation of synapse organization(GO:0050807)
0.0 0.0 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.0 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0031281 positive regulation of cyclase activity(GO:0031281)
0.0 0.0 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0 0.0 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.0 GO:0042504 tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0 0.1 GO:0060674 placenta blood vessel development(GO:0060674)
0.0 0.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.0 0.0 GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein(GO:0042522)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.0 GO:0002024 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.0 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0010001 glial cell differentiation(GO:0010001)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.2 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.0 0.1 GO:0098876 Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.0 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.9 GO:0005916 fascia adherens(GO:0005916)
0.1 0.2 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.1 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.4 GO:0001527 microfibril(GO:0001527)
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.1 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.5 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.8 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.3 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 5.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0044309 neuron spine(GO:0044309)
0.0 0.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0070083 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.1 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)
0.0 0.8 GO:0030426 growth cone(GO:0030426)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 1.1 GO:0030016 myofibril(GO:0030016)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.9 GO:0043296 apical junction complex(GO:0043296)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.0 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.0 GO:0001939 female pronucleus(GO:0001939)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.6 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.6 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0070052 collagen V binding(GO:0070052)
0.1 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.2 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.9 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.5 GO:0043498 obsolete cell surface binding(GO:0043498)
0.0 0.6 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 2.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.0 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.3 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.0 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.0 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.0 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.0 GO:0016160 alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0 0.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.0 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.0 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.5 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.0 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 1.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 ST GA13 PATHWAY G alpha 13 Pathway
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 3.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.7 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 2.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME PI3K EVENTS IN ERBB2 SIGNALING Genes involved in PI3K events in ERBB2 signaling
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.0 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.8 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.0 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis