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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXA2_HOXB1

Z-value: 0.40

Motif logo

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Transcription factors associated with HOXA2_HOXB1

Gene Symbol Gene ID Gene Info
HOXA2
ENSG00000105996.5 homeobox A2
HOXB1
ENSG00000120094.6 homeobox B1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_27142124_27142281HOXA22280.8207400.844.9e-03Click!
chr7_27142737_27142888HOXA23820.6748610.845.1e-03Click!
chr7_27140714_27141098HOXA215240.1691560.817.5e-03Click!
chr7_27143124_27143275HOXA27690.3840450.771.6e-02Click!
chr7_27142394_27142575HOXA2540.9301370.742.2e-02Click!
chr17_46606887_46607038HOXB113100.2460610.742.3e-02Click!
chr17_46607108_46607259HOXB110890.3000340.684.3e-02Click!

Activity of the HOXA2_HOXB1 motif across conditions

Conditions sorted by the z-value of the HOXA2_HOXB1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_121494510_121494857 0.31 GLI2
 GLI family zinc finger 2
 860
 0.74
chr9_34745263_34745414 0.24 FAM205A
 family with sequence similarity 205, member A
 15874
 0.13
chr17_17317253_17317688 0.22 ENSG00000201741
 .
 46288
 0.12
chr12_85305887_85306488 0.21 SLC6A15
 solute carrier family 6 (neutral amino acid transporter), member 15
 384
 0.92
chr11_122072235_122072431 0.20 ENSG00000207994
 .
 49317
 0.12
chr5_100168975_100169126 0.19 ENSG00000221263
 .
 16781
 0.26
chr19_464760_464911 0.18 SHC2
 SHC (Src homology 2 domain containing) transforming protein 2
 3839
 0.12
chr16_16115866_16116017 0.17 ABCC1
 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
 12228
 0.24
chr3_159482295_159482916 0.16 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 287
 0.9
chr2_53971971_53972122 0.16 GPR75-ASB3
 GPR75-ASB3 readthrough
 20640
 0.16
chr11_34706995_34707273 0.16 EHF
 ets homologous factor
 42960
 0.19
chrX_45482024_45482567 0.15 ENSG00000207870
 .
 123399
 0.06
chr2_54684400_54684738 0.15 SPTBN1
 spectrin, beta, non-erythrocytic 1
 171
 0.97
chr1_83285095_83285395 0.15 LPHN2
 latrophilin 2
 839672
 0.0
chr14_53158961_53159226 0.15 ERO1L
 ERO1-like (S. cerevisiae)
 3154
 0.22
chr1_87244034_87244185 0.15 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 73531
 0.09
chr2_74968036_74968578 0.14 SEMA4F
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
 86869
 0.07
chr7_22233477_22233744 0.14 RAPGEF5
 Rap guanine nucleotide exchange factor (GEF) 5
 83
 0.98
chr15_74880905_74881056 0.14 CLK3
 CDC-like kinase 3
 19733
 0.14
chr18_53214040_53214242 0.14 TCF4
 transcription factor 4
 36141
 0.18
chr5_10757151_10757327 0.14 CTD-2154B17.4
3938
 0.26
chr14_103588344_103588755 0.13 TNFAIP2
 tumor necrosis factor, alpha-induced protein 2
 1249
 0.43
chr1_208137959_208138110 0.13 CD34
 CD34 molecule
 53287
 0.17
chr21_43422426_43422615 0.13 ZBTB21
 zinc finger and BTB domain containing 21
 5646
 0.21
chr7_5467738_5468320 0.13 TNRC18
 trinucleotide repeat containing 18
 2984
 0.19
chr20_61468182_61468333 0.13 COL9A3
 collagen, type IX, alpha 3
 19094
 0.11
chr11_96062035_96062186 0.13 ENSG00000266192
 .
 12492
 0.2
chr2_222367084_222367382 0.13 EPHA4
 EPH receptor A4
 47
 0.98
chr4_8702215_8702366 0.13 CPZ
 carboxypeptidase Z
 98593
 0.07
chr13_30009560_30009804 0.13 MTUS2
 microtubule associated tumor suppressor candidate 2
 6836
 0.28
chr7_100773540_100774051 0.13 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 3416
 0.13
chr11_27739578_27739815 0.13 BDNF
 brain-derived neurotrophic factor
 1598
 0.49
chr17_36623721_36623872 0.13 ARHGAP23
 Rho GTPase activating protein 23
 4384
 0.19
chrX_130902480_130902797 0.12 ENSG00000200587
 .
 170346
 0.03
chr9_27408498_27408649 0.12 RP11-298E2.2
16841
 0.25
chr21_28215601_28215791 0.12 ADAMTS1
 ADAM metallopeptidase with thrombospondin type 1 motif, 1
 163
 0.97
chr10_105614245_105615135 0.12 SH3PXD2A
 SH3 and PX domains 2A
 474
 0.82
chr18_74798828_74799607 0.12 MBP
 myelin basic protein
 18000
 0.27
chr10_28491840_28491991 0.12 MPP7
 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
 35751
 0.21
chr14_81893853_81894004 0.12 STON2
 stonin 2
 180
 0.97
chr2_183225036_183225187 0.11 ENSG00000242121
 .
 46100
 0.17
chr11_30606067_30606222 0.11 RP5-1024C24.1
434
 0.82
chr14_50468177_50468632 0.11 C14orf182
 chromosome 14 open reading frame 182
 5834
 0.2
chr16_5648936_5649087 0.11 RP11-124K4.1
12283
 0.3
chr8_25793197_25793466 0.11 EBF2
 early B-cell factor 2
 47899
 0.19
chr14_24019702_24019853 0.11 ZFHX2
 zinc finger homeobox 2
 1081
 0.33
chr3_156480231_156480382 0.11 LEKR1
 leucine, glutamate and lysine rich 1
 63783
 0.12
chr11_3181150_3181578 0.11 OSBPL5
 oxysterol binding protein-like 5
 1259
 0.4
chr19_10736478_10736985 0.11 SLC44A2
 solute carrier family 44 (choline transporter), member 2
 530
 0.65
chr18_9107793_9107944 0.11 NDUFV2
 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
 3788
 0.2
chr8_22250007_22250158 0.11 SLC39A14
 solute carrier family 39 (zinc transporter), member 14
 261
 0.91
chr7_75924108_75924402 0.11 ENSG00000263569
 .
 6147
 0.16
chr12_132629597_132629942 0.11 NOC4L
 nucleolar complex associated 4 homolog (S. cerevisiae)
 460
 0.65
chr6_102178821_102179006 0.11 GRIK2
 glutamate receptor, ionotropic, kainate 2
 54269
 0.19
chr7_156851742_156851893 0.11 MNX1-AS1
 MNX1 antisense RNA 1 (head to head)
 48318
 0.11
chr10_33620428_33620906 0.11 NRP1
 neuropilin 1
 2643
 0.37
chr2_134391396_134391547 0.10 ENSG00000200708
 .
 37809
 0.2
chr16_49890203_49890582 0.10 ZNF423
 zinc finger protein 423
 346
 0.91
chrX_11456470_11456766 0.10 ARHGAP6
 Rho GTPase activating protein 6
 10725
 0.3
chr17_71068251_71068402 0.10 SLC39A11
 solute carrier family 39, member 11
 17577
 0.24
chr15_95869891_95870263 0.10 ENSG00000222076
 .
 418956
 0.01
chr15_32976738_32976906 0.10 RP11-1000B6.2
11556
 0.16
chr18_26092204_26092423 0.10 CDH2
 cadherin 2, type 1, N-cadherin (neuronal)
 334903
 0.01
chr2_28178102_28178322 0.10 ENSG00000265321
 .
 41022
 0.15
chr8_37378833_37379079 0.10 RP11-150O12.6
4417
 0.31
chr10_110004648_110004799 0.10 ENSG00000222436
 .
 696345
 0.0
chr10_5670766_5671061 0.10 ENSG00000240577
 .
 2513
 0.27
chr3_98619314_98619465 0.10 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 626
 0.66
chr7_24576451_24576602 0.10 ENSG00000206877
 .
 425
 0.89
chr17_39577204_39577355 0.10 KRT37
 keratin 37
 3496
 0.11
chr5_159738704_159739455 0.09 CCNJL
 cyclin J-like
 404
 0.84
chr3_129204924_129205100 0.09 IFT122
 intraflagellar transport 122 homolog (Chlamydomonas)
 2022
 0.27
chr3_159451541_159451741 0.09 IQCJ-SCHIP1
 IQCJ-SCHIP1 readthrough
 29861
 0.17
chr2_180990617_180990780 0.09 CWC22
 CWC22 spliceosome-associated protein homolog (S. cerevisiae)
 118858
 0.07
chr7_123389310_123389704 0.09 RP11-390E23.6
385
 0.47
chr9_86892548_86892699 0.09 RP11-380F14.2
511
 0.86
chr17_38267528_38268059 0.09 MSL1
 male-specific lethal 1 homolog (Drosophila)
 10758
 0.11
chr17_69972427_69972645 0.09 AC007461.1
 Uncharacterized protein
 63628
 0.15
chr14_55137368_55137519 0.09 SAMD4A
 sterile alpha motif domain containing 4A
 84108
 0.09
chr8_26370931_26371439 0.09 PNMA2
 paraneoplastic Ma antigen 2
 423
 0.6
chr21_33244856_33245438 0.09 HUNK
 hormonally up-regulated Neu-associated kinase
 481
 0.88
chr2_65804604_65804761 0.09 ENSG00000251900
 .
 22014
 0.21
chr7_23509552_23510001 0.09 IGF2BP3
 insulin-like growth factor 2 mRNA binding protein 3
 310
 0.88
chr7_131582308_131582459 0.09 ENSG00000252849
 .
 18698
 0.25
chr7_44922681_44922832 0.09 ENSG00000264326
 .
 1357
 0.26
chr3_72131377_72131562 0.09 ENSG00000212070
 .
 180110
 0.03
chr8_59956242_59956393 0.09 RP11-328K2.1
50820
 0.14
chr12_114844132_114844283 0.09 TBX5
 T-box 5
 318
 0.89
chr8_116463616_116464117 0.09 TRPS1
 trichorhinophalangeal syndrome I
 40582
 0.2
chr3_13689202_13689353 0.09 LINC00620
 long intergenic non-protein coding RNA 620
 2919
 0.28
chr7_25891701_25892366 0.09 ENSG00000199085
 .
 97573
 0.09
chr10_8201743_8201894 0.09 GATA3
 GATA binding protein 3
 105049
 0.08
chr10_77168132_77169350 0.09 ENSG00000237149
 .
 5929
 0.2
chr9_128512876_128513197 0.09 PBX3
 pre-B-cell leukemia homeobox 3
 2558
 0.37
chr10_127779801_127780118 0.08 ENSG00000222740
 .
 54192
 0.14
chr2_205180048_205180265 0.08 PARD3B
 par-3 family cell polarity regulator beta
 230360
 0.02
chr5_15501266_15501663 0.08 FBXL7
 F-box and leucine-rich repeat protein 7
 83
 0.99
chr2_114035017_114035267 0.08 PAX8
 paired box 8
 829
 0.59
chr17_75471247_75471398 0.08 SEPT9
 septin 9
 3
 0.97
chr4_160220043_160220341 0.08 ENSG00000216089
 .
 3326
 0.3
chr2_42796417_42796822 0.08 MTA3
 metastasis associated 1 family, member 3
 95
 0.98
chr15_37394480_37395011 0.08 MEIS2
 Meis homeobox 2
 1241
 0.49
chr3_61580182_61580471 0.08 PTPRG
 protein tyrosine phosphatase, receptor type, G
 32741
 0.25
chr12_47671859_47672010 0.08 RP11-493L12.3
870
 0.66
chr3_68697737_68697888 0.08 ENSG00000212095
 .
 13745
 0.3
chr12_25877270_25877421 0.08 ENSG00000222950
 .
 55158
 0.14
chr11_61780107_61780258 0.08 AP003733.1
 Uncharacterized protein; cDNA FLJ36460 fis, clone THYMU2014801
 44729
 0.1
chr2_27301899_27302732 0.08 EMILIN1
 elastin microfibril interfacer 1
 880
 0.32
chr12_54672473_54672704 0.08 CBX5
 chromobox homolog 5
 1298
 0.19
chr7_93485635_93485786 0.08 TFPI2
 tissue factor pathway inhibitor 2
 33772
 0.15
chr5_134722208_134722661 0.08 H2AFY
 H2A histone family, member Y
 12467
 0.16
chr12_123574141_123574292 0.08 PITPNM2
 phosphatidylinositol transfer protein, membrane-associated 2
 8336
 0.19
chr4_6992958_6993109 0.08 AC097382.5
4035
 0.13
chr3_78853664_78853815 0.08 ENSG00000240964
 .
 133703
 0.05
chr2_235403849_235404784 0.08 ARL4C
 ADP-ribosylation factor-like 4C
 928
 0.74
chr1_8202972_8203123 0.08 ENSG00000200975
 .
 63610
 0.11
chr11_122028064_122028812 0.08 ENSG00000207994
 .
 5422
 0.19
chr9_89069847_89070053 0.08 ENSG00000222293
 .
 31907
 0.23
chr4_105747663_105747814 0.08 ENSG00000251906
 .
 148081
 0.04
chr3_61549164_61549336 0.08 PTPRG
 protein tyrosine phosphatase, receptor type, G
 1665
 0.55
chr10_99932028_99932445 0.08 R3HCC1L
 R3H domain and coiled-coil containing 1-like
 9596
 0.25
chr16_85645006_85645418 0.08 GSE1
 Gse1 coiled-coil protein
 197
 0.95
chr1_165868486_165868637 0.07 RP11-525G13.2
1359
 0.44
chrX_106984928_106985096 0.07 TSC22D3
 TSC22 domain family, member 3
 19510
 0.2
chr1_56547076_56547335 0.07 PIGQP1
 phosphatidylinositol glycan anchor biosynthesis, class Q pseudogene 1
 142252
 0.05
chr10_102322629_102322843 0.07 HIF1AN
 hypoxia inducible factor 1, alpha subunit inhibitor
 27120
 0.15
chr2_14896967_14897186 0.07 AC011897.1
 Uncharacterized protein
 121861
 0.06
chr9_685775_685926 0.07 RP11-130C19.3
295
 0.92
chr14_21093852_21094122 0.07 OR6S1
 olfactory receptor, family 6, subfamily S, member 1
 15863
 0.1
chr1_84084018_84084169 0.07 ENSG00000223231
 .
 175467
 0.03
chr15_33148553_33148741 0.07 FMN1
 formin 1
 31808
 0.17
chr13_98826337_98826632 0.07 RNF113B
 ring finger protein 113B
 3035
 0.21
chr5_59508772_59508923 0.07 PDE4D
 phosphodiesterase 4D, cAMP-specific
 27422
 0.24
chr21_42213476_42213627 0.07 DSCAM
 Down syndrome cell adhesion molecule
 5514
 0.33
chr19_5681315_5681466 0.07 RPL36
 ribosomal protein L36
 197
 0.45
chr5_17021245_17021396 0.07 BASP1
 brain abundant, membrane attached signal protein 1
 44387
 0.15
chr14_88921501_88921652 0.07 PTPN21
 protein tyrosine phosphatase, non-receptor type 21
 14384
 0.17
chr4_172734546_172734879 0.07 GALNTL6
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
 58
 0.99
chr3_169377883_169378034 0.07 MECOM
 MDS1 and EVI1 complex locus
 3220
 0.23
chr10_63734627_63734778 0.07 ENSG00000221272
 .
 47925
 0.17
chr2_138723355_138723506 0.07 HNMT
 histamine N-methyltransferase
 1387
 0.61
chr5_14265991_14266171 0.07 TRIO
 trio Rho guanine nucleotide exchange factor
 25005
 0.28
chr16_88228496_88228647 0.07 BANP
 BTG3 associated nuclear protein
 224947
 0.02
chr3_98612768_98613177 0.07 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 7043
 0.19
chr6_142335140_142335592 0.07 RP11-137J7.2
74004
 0.11
chr1_87239567_87240110 0.07 SH3GLB1
 SH3-domain GRB2-like endophilin B1
 69260
 0.09
chr6_33384595_33384833 0.07 CUTA
 cutA divalent cation tolerance homolog (E. coli)
 984
 0.34
chr7_83823215_83823431 0.07 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 894
 0.76
chr18_45968069_45968289 0.07 ZBTB7C
 zinc finger and BTB domain containing 7C
 31056
 0.17
chr1_54793079_54793243 0.07 RP5-997D24.3
42083
 0.14
chr1_21650807_21651093 0.07 ECE1
 endothelin converting enzyme 1
 21047
 0.18
chr2_31636273_31636424 0.07 XDH
 xanthine dehydrogenase
 1233
 0.61
chr10_94581983_94582410 0.07 EXOC6
 exocyst complex component 6
 8739
 0.28
chr16_65566073_65566543 0.07 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 410040
 0.01
chr16_51465176_51465516 0.07 ENSG00000223168
 .
 240128
 0.02
chr3_52140725_52140876 0.07 LINC00696
 long intergenic non-protein coding RNA 696
 43233
 0.09
chr4_102267340_102267537 0.07 PPP3CA
 protein phosphatase 3, catalytic subunit, alpha isozyme
 515
 0.73
chr6_163664912_163665063 0.07 ENSG00000239136
 .
 17045
 0.25
chr4_26203423_26203574 0.07 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 38421
 0.23
chr3_42697942_42698093 0.07 RP4-613B23.1
2137
 0.17
chr4_159732250_159732401 0.07 FNIP2
 folliculin interacting protein 2
 4925
 0.23
chr18_61148002_61148153 0.06 SERPINB5
 serpin peptidase inhibitor, clade B (ovalbumin), member 5
 3717
 0.21
chr8_135790645_135790802 0.06 ENSG00000207582
 .
 22127
 0.21
chrX_123128269_123128420 0.06 STAG2
 stromal antigen 2
 31324
 0.2
chr4_143739251_143739537 0.06 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 28049
 0.27
chr18_4269017_4269168 0.06 DLGAP1-AS5
 DLGAP1 antisense RNA 5
 4459
 0.35
chr11_12699867_12700018 0.06 TEAD1
 TEA domain family member 1 (SV40 transcriptional enhancer factor)
 2892
 0.38
chr19_914980_915131 0.06 R3HDM4
 R3H domain containing 4
 1815
 0.15
chr2_12458046_12458293 0.06 ENSG00000207183
 .
 93458
 0.09
chr15_72529055_72529849 0.06 PKM
 pyruvate kinase, muscle
 5288
 0.17
chr12_21927150_21927652 0.06 KCNJ8
 potassium inwardly-rectifying channel, subfamily J, member 8
 354
 0.86
chr4_157862974_157863267 0.06 PDGFC
 platelet derived growth factor C
 28935
 0.19
chr2_100635044_100635528 0.06 AFF3
 AF4/FMR2 family, member 3
 85706
 0.09
chr2_85640026_85640421 0.06 CAPG
 capping protein (actin filament), gelsolin-like
 939
 0.34
chr7_6309088_6309239 0.06 CYTH3
 cytohesin 3
 3112
 0.25
chr8_131144625_131144776 0.06 ASAP1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
 13932
 0.2
chr1_164535324_164535475 0.06 PBX1
 pre-B-cell leukemia homeobox 1
 3357
 0.34
chr5_142625895_142626046 0.06 ARHGAP26
 Rho GTPase activating protein 26
 39205
 0.19
chr6_121756849_121757212 0.06 GJA1
 gap junction protein, alpha 1, 43kDa
 192
 0.94
chr7_2235658_2235809 0.06 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 27530
 0.17
chr10_53222210_53222361 0.06 RP11-539E19.2
159959
 0.04
chr4_184827832_184828262 0.06 STOX2
 storkhead box 2
 1538
 0.51
chr17_4711009_4711212 0.06 PLD2
 phospholipase D2
 253
 0.82
chr7_16168928_16169137 0.06 ISPD-AS1
 ISPD antisense RNA 1
 81081
 0.11
chr7_17315289_17315760 0.06 AC003075.4
5403
 0.27
chr10_11872880_11873031 0.06 PROSER2
 proline and serine-rich protein 2
 727
 0.72
chr14_21731452_21731695 0.06 HNRNPC
 heterogeneous nuclear ribonucleoprotein C (C1/C2)
 737
 0.64
chr14_62232461_62232666 0.06 SNAPC1
 small nuclear RNA activating complex, polypeptide 1, 43kDa
 3488
 0.33
chr10_119312526_119312804 0.06 EMX2OS
 EMX2 opposite strand/antisense RNA
 8086
 0.24
chr6_164616974_164617125 0.06 ENSG00000266128
 .
 355456
 0.01
chr6_168719854_168720005 0.06 DACT2
 dishevelled-binding antagonist of beta-catenin 2
 461
 0.86
chr6_76458966_76459788 0.06 MYO6
 myosin VI
 328
 0.89
chr7_39641818_39642080 0.06 AC004837.4
7940
 0.18
chr17_62655006_62655429 0.06 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
 2813
 0.3
chr10_102505217_102505492 0.06 PAX2
 paired box 2
 114
 0.98
chr22_46460492_46460792 0.06 RP6-109B7.4
5129
 0.11
chr16_66752038_66752189 0.06 RP11-63M22.2
2687
 0.2
chr11_119583124_119583275 0.06 PVRL1
 poliovirus receptor-related 1 (herpesvirus entry mediator C)
 16064
 0.18
chr1_26496798_26497060 0.06 RP11-96L14.7
375
 0.52
chr6_8434475_8434734 0.06 SLC35B3
 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
 1112
 0.69

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXA2_HOXB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1 0.2 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.1 GO:1901889 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0008091 spectrin(GO:0008091)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0001159 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters