Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HOXA5

Z-value: 3.19

Motif logo

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Transcription factors associated with HOXA5

Gene Symbol Gene ID Gene Info
ENSG00000106004.4 HOXA5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HOXA5chr7_27184642_2718486414660.144402-0.501.7e-01Click!
HOXA5chr7_27184354_2718450511420.197870-0.452.2e-01Click!
HOXA5chr7_27184880_2718503116680.123048-0.343.7e-01Click!
HOXA5chr7_27182133_2718235610430.219642-0.235.5e-01Click!
HOXA5chr7_27181909_2718206013030.164586-0.235.5e-01Click!

Activity of the HOXA5 motif across conditions

Conditions sorted by the z-value of the HOXA5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_87036535_87037613 1.74 VGLL3
vestigial like 3 (Drosophila)
2778
0.42
chr18_53068422_53068903 1.56 TCF4
transcription factor 4
96
0.98
chr9_18474095_18474958 1.03 ADAMTSL1
ADAMTS-like 1
295
0.95
chr6_116833589_116833880 0.98 TRAPPC3L
trafficking protein particle complex 3-like
228
0.83
chr8_37310276_37310698 0.93 RP11-150O12.6

64052
0.13
chr11_121970307_121971111 0.93 ENSG00000207971
.
157
0.79
chr4_54063057_54063462 0.92 ENSG00000207385
.
68475
0.13
chr5_151065704_151066114 0.91 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
615
0.66
chr7_6296015_6296815 0.89 CYTH3
cytohesin 3
15860
0.17
chr6_85823864_85824548 0.87 NT5E
5'-nucleotidase, ecto (CD73)
335603
0.01
chr7_19145980_19146451 0.85 AC003986.6

5882
0.17
chr11_13462262_13462675 0.85 BTBD10
BTB (POZ) domain containing 10
642
0.78
chr11_121967218_121967559 0.84 ENSG00000207971
.
3164
0.21
chr6_148829582_148830289 0.78 ENSG00000223322
.
15441
0.29
chr1_225842736_225843127 0.77 ENAH
enabled homolog (Drosophila)
2087
0.34
chr15_49715834_49715985 0.76 FGF7
fibroblast growth factor 7
452
0.86
chr18_56245541_56245920 0.74 RP11-126O1.2

21428
0.14
chr2_207077565_207077805 0.73 GPR1
G protein-coupled receptor 1
410
0.79
chr4_81195528_81195918 0.71 FGF5
fibroblast growth factor 5
7930
0.26
chr1_94701176_94701460 0.71 ARHGAP29
Rho GTPase activating protein 29
1803
0.43
chr4_141013667_141013926 0.71 RP11-392B6.1

35373
0.19
chr4_15471989_15472140 0.70 CC2D2A
coiled-coil and C2 domain containing 2A
427
0.85
chr1_65005729_65006114 0.70 ENSG00000264470
.
39609
0.19
chr5_121409447_121409998 0.70 LOX
lysyl oxidase
4258
0.27
chr11_123178720_123179203 0.69 ENSG00000200496
.
6863
0.25
chr12_19358566_19358717 0.68 PLEKHA5
pleckstrin homology domain containing, family A member 5
382
0.89
chr15_96884556_96884898 0.68 ENSG00000222651
.
8237
0.16
chr9_100069620_100070257 0.67 CCDC180
coiled-coil domain containing 180
3
0.98
chr5_88120627_88121096 0.66 MEF2C
myocyte enhancer factor 2C
704
0.78
chr16_68440843_68441106 0.64 SMPD3
sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
34813
0.11
chr5_95068939_95069254 0.63 CTD-2154I11.2

1097
0.44
chr3_133132283_133132447 0.63 BFSP2
beaded filament structural protein 2, phakinin
13526
0.23
chr6_155510812_155511010 0.63 TIAM2
T-cell lymphoma invasion and metastasis 2
26860
0.21
chr4_82487360_82487596 0.62 RASGEF1B
RasGEF domain family, member 1B
94409
0.09
chr5_77147504_77148481 0.62 TBCA
tubulin folding cofactor A
16612
0.28
chr12_50748152_50748528 0.61 FAM186A
family with sequence similarity 186, member A
3672
0.22
chr10_86185479_86185663 0.61 CCSER2
coiled-coil serine-rich protein 2
876
0.74
chr3_106060605_106060757 0.61 ENSG00000200610
.
174063
0.04
chr5_88178054_88178448 0.61 MEF2C
myocyte enhancer factor 2C
713
0.52
chr4_187590867_187591207 0.61 FAT1
FAT atypical cadherin 1
53972
0.15
chr8_42063953_42065062 0.61 PLAT
plasminogen activator, tissue
576
0.71
chr8_108469708_108470050 0.60 ANGPT1
angiopoietin 1
37344
0.23
chr7_94025506_94025990 0.60 COL1A2
collagen, type I, alpha 2
1875
0.46
chr15_96878987_96879612 0.60 ENSG00000222651
.
2809
0.21
chr1_107816526_107816677 0.60 NTNG1
netrin G1
125385
0.06
chr18_53525579_53526226 0.60 TCF4
transcription factor 4
193884
0.03
chr8_12986347_12986498 0.60 DLC1
deleted in liver cancer 1
4561
0.27
chr14_50819908_50820192 0.60 CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
12203
0.17
chr13_28975822_28976139 0.59 FLT1
fms-related tyrosine kinase 1
55554
0.16
chr2_27301899_27302732 0.59 EMILIN1
elastin microfibril interfacer 1
880
0.32
chr1_178341100_178341570 0.59 RASAL2
RAS protein activator like 2
30729
0.22
chr13_45145551_45145847 0.59 TSC22D1
TSC22 domain family, member 1
4693
0.31
chr16_69430418_69430738 0.59 TERF2
telomeric repeat binding factor 2
10687
0.13
chr2_192710069_192710427 0.57 AC098617.1

1017
0.51
chr2_109271526_109272143 0.57 LIMS1
LIM and senescent cell antigen-like domains 1
325
0.91
chr18_55468661_55468977 0.57 ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
1508
0.47
chr10_33620428_33620906 0.57 NRP1
neuropilin 1
2643
0.37
chr2_66668625_66669005 0.57 AC092669.1

153
0.89
chr1_172313169_172313650 0.56 ENSG00000252354
.
3874
0.23
chr3_87035332_87035763 0.56 VGLL3
vestigial like 3 (Drosophila)
4305
0.37
chr9_81322437_81322726 0.56 PSAT1
phosphoserine aminotransferase 1
410522
0.01
chr14_40142320_40142471 0.55 FBXO33
F-box protein 33
240691
0.02
chr8_89311514_89311910 0.55 RP11-586K2.1

27353
0.2
chr2_243030793_243031816 0.55 AC093642.5

460
0.62
chr1_150245169_150245508 0.55 C1orf54
chromosome 1 open reading frame 54
155
0.89
chr1_170775230_170775381 0.55 MROH9
maestro heat-like repeat family member 9
129307
0.05
chr16_62022994_62023145 0.54 CDH8
cadherin 8, type 2
32437
0.22
chr8_13370846_13370997 0.54 DLC1
deleted in liver cancer 1
1353
0.48
chr15_71704699_71704850 0.54 ENSG00000252813
.
63052
0.13
chr12_13500598_13500781 0.54 C12orf36
chromosome 12 open reading frame 36
28675
0.21
chr6_56706635_56706858 0.53 DST
dystonin
1197
0.47
chr7_137617943_137618298 0.53 CREB3L2
cAMP responsive element binding protein 3-like 2
516
0.81
chr3_100711576_100712203 0.53 ABI3BP
ABI family, member 3 (NESH) binding protein
408
0.89
chr3_55513844_55514078 0.53 WNT5A
wingless-type MMTV integration site family, member 5A
1263
0.55
chr4_20257540_20257840 0.53 SLIT2
slit homolog 2 (Drosophila)
1147
0.67
chr1_221165558_221165709 0.53 HLX
H2.0-like homeobox
111049
0.06
chr16_69854762_69854918 0.53 WWP2
WW domain containing E3 ubiquitin protein ligase 2
17800
0.14
chr6_113779452_113779603 0.52 ENSG00000222677
.
56662
0.16
chr10_69597676_69597902 0.52 DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
28
0.98
chr6_25312716_25313084 0.52 ENSG00000207286
.
25139
0.15
chr17_79317268_79317735 0.52 TMEM105
transmembrane protein 105
13027
0.13
chr14_81919439_81919650 0.52 STON2
stonin 2
16735
0.28
chr7_94026049_94026200 0.51 COL1A2
collagen, type I, alpha 2
2251
0.42
chr9_16628311_16628540 0.51 RP11-62F24.1

2751
0.37
chr4_159093168_159093728 0.51 RP11-597D13.9

281
0.64
chr2_216565416_216565653 0.51 ENSG00000212055
.
178108
0.03
chr10_76092894_76093045 0.50 ADK
adenosine kinase
156448
0.04
chr11_72975754_72976333 0.50 P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
232
0.91
chr4_71479096_71479386 0.50 ENAM
enamelin
15220
0.15
chr4_151500337_151500655 0.50 RP11-1336O20.2

255
0.93
chr19_47473743_47473975 0.50 ENSG00000252071
.
22313
0.15
chr4_105315656_105315807 0.49 ENSG00000272082
.
96302
0.08
chr7_93930220_93930402 0.49 COL1A2
collagen, type I, alpha 2
93562
0.09
chr12_91575790_91576058 0.49 DCN
decorin
505
0.87
chr1_119521934_119522435 0.49 TBX15
T-box 15
8244
0.28
chr3_49237110_49237583 0.49 CCDC36
coiled-coil domain containing 36
403
0.74
chr10_17276996_17277147 0.49 RP11-124N14.3

239
0.91
chr14_52707563_52708006 0.49 PTGDR
prostaglandin D2 receptor (DP)
26647
0.22
chr7_15956823_15957170 0.49 MEOX2
mesenchyme homeobox 2
230559
0.02
chr6_38323224_38323482 0.49 ENSG00000238716
.
3652
0.35
chr6_83664739_83664926 0.49 RP11-445L13__B.3

22512
0.24
chr6_140525333_140525555 0.49 ENSG00000263514
.
945
0.7
chr4_177420954_177421115 0.49 RP11-313E19.2

169738
0.03
chr5_77886889_77887187 0.49 LHFPL2
lipoma HMGIC fusion partner-like 2
42064
0.21
chr2_199237110_199237329 0.49 ENSG00000252511
.
194234
0.03
chr15_89532559_89532920 0.48 ENSG00000265866
.
17056
0.2
chr4_134071254_134071890 0.48 PCDH10
protocadherin 10
1102
0.7
chr3_114136352_114136558 0.48 ZBTB20-AS1
ZBTB20 antisense RNA 1
29939
0.18
chr4_160169630_160170007 0.48 RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
18215
0.23
chr11_12529707_12530128 0.48 PARVA
parvin, alpha
55635
0.15
chr1_78546733_78546884 0.48 ENSG00000251958
.
7959
0.18
chr7_36301220_36301371 0.48 AC007327.5

30579
0.15
chr14_52122113_52122363 0.48 FRMD6
FERM domain containing 6
3540
0.25
chr8_18938326_18938477 0.48 PSD3
pleckstrin and Sec7 domain containing 3
3839
0.34
chr14_93736061_93736314 0.48 BTBD7
BTB (POZ) domain containing 7
24308
0.15
chrX_153755544_153755807 0.48 WI2-89031B12.1

8720
0.08
chr2_182929835_182929986 0.47 ENSG00000222418
.
16361
0.21
chr8_89336653_89337119 0.47 RP11-586K2.1

2179
0.33
chr4_72132010_72132365 0.47 SLC4A4
solute carrier family 4 (sodium bicarbonate cotransporter), member 4
72583
0.13
chr3_112356169_112356393 0.47 CCDC80
coiled-coil domain containing 80
663
0.77
chr4_188104639_188104855 0.47 ENSG00000252382
.
326137
0.01
chr11_121800761_121801203 0.47 ENSG00000252556
.
74081
0.11
chr15_96881380_96881711 0.47 ENSG00000222651
.
5055
0.17
chr11_75272983_75274329 0.47 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
216
0.91
chr3_175244326_175245006 0.46 ENSG00000201648
.
82601
0.1
chr5_61389615_61389794 0.46 ENSG00000251983
.
52788
0.18
chr7_27235436_27235587 0.46 HOTTIP
HOXA distal transcript antisense RNA
2683
0.1
chr2_138722074_138722590 0.46 HNMT
histamine N-methyltransferase
289
0.95
chr11_121800053_121800533 0.46 ENSG00000252556
.
74770
0.11
chr11_126506918_126507382 0.46 RP11-115C10.1

15597
0.26
chr16_11444934_11445085 0.46 RP11-485G7.6

1831
0.18
chr3_69493986_69494187 0.46 FRMD4B
FERM domain containing 4B
58656
0.16
chr2_176992012_176992333 0.45 HOXD8
homeobox D8
2250
0.12
chr1_230312644_230313027 0.45 RP5-956O18.2

91394
0.08
chr9_27276437_27276611 0.45 EQTN
equatorin, sperm acrosome associated
20610
0.24
chr2_180427189_180427340 0.45 ZNF385B
zinc finger protein 385B
51
0.99
chr5_124536619_124536868 0.45 ENSG00000222107
.
150081
0.05
chr5_63461313_63462499 0.45 RNF180
ring finger protein 180
83
0.99
chr4_20258902_20259191 0.45 SLIT2
slit homolog 2 (Drosophila)
2503
0.44
chr17_64187141_64188685 0.45 CEP112
centrosomal protein 112kDa
60
0.98
chr4_123631846_123631997 0.45 BBS12
Bardet-Biedl syndrome 12
21936
0.21
chr20_32119305_32119472 0.45 CBFA2T2
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
30752
0.15
chr2_239909052_239909326 0.45 ENSG00000211566
.
14483
0.15
chr19_21657403_21658104 0.45 ZNF429
zinc finger protein 429
30613
0.19
chr5_58882867_58883091 0.44 PDE4D
phosphodiesterase 4D, cAMP-specific
654
0.83
chr2_55644066_55644508 0.44 CCDC88A
coiled-coil domain containing 88A
2125
0.27
chr15_28437348_28437499 0.44 HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
17854
0.25
chr1_163041321_163041476 0.44 RGS4
regulator of G-protein signaling 4
436
0.89
chr3_37218704_37218986 0.44 LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
822
0.54
chr8_121792837_121792988 0.44 RP11-713M15.1

19419
0.2
chr14_24837426_24838101 0.44 NFATC4
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
216
0.85
chr2_145278154_145278598 0.44 ZEB2-AS1
ZEB2 antisense RNA 1
203
0.55
chr4_41574676_41574848 0.44 LIMCH1
LIM and calponin homology domains 1
34571
0.21
chr8_72776934_72777085 0.44 MSC
musculin
20306
0.17
chr3_192551184_192551388 0.44 FGF12
fibroblast growth factor 12
65733
0.12
chr20_50664340_50664598 0.43 ZFP64
ZFP64 zinc finger protein
50536
0.17
chr3_167784999_167785150 0.43 GOLIM4
golgi integral membrane protein 4
28058
0.26
chr4_55093553_55093862 0.43 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
1557
0.51
chr1_186153285_186153546 0.43 GS1-174L6.4

6981
0.23
chr5_39422896_39423047 0.43 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
1999
0.45
chr4_77704559_77704807 0.43 RP11-359D14.3

18434
0.19
chr5_82664441_82664703 0.43 VCAN
versican
102712
0.08
chr7_82072002_82072462 0.43 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
799
0.78
chr9_83413109_83413260 0.43 ENSG00000221581
.
63940
0.16
chr8_16622129_16622507 0.43 ENSG00000264092
.
98687
0.08
chr9_80366312_80366540 0.43 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
71489
0.12
chr13_52979416_52980324 0.43 THSD1
thrombospondin, type I, domain containing 1
393
0.85
chr4_134068181_134068851 0.43 PCDH10
protocadherin 10
1954
0.52
chr6_85474025_85474422 0.43 TBX18
T-box 18
14
0.99
chr3_51377185_51377336 0.43 MANF
mesencephalic astrocyte-derived neurotrophic factor
45218
0.15
chr1_245361051_245361416 0.43 RP11-62I21.1

36570
0.15
chr10_15693138_15693289 0.43 ITGA8
integrin, alpha 8
68911
0.13
chr3_190436802_190436953 0.43 ENSG00000223117
.
76925
0.11
chr11_5618493_5618678 0.43 TRIM6
tripartite motif containing 6
549
0.42
chr4_107240189_107240340 0.43 TBCK
TBC1 domain containing kinase
2388
0.31
chr16_54965711_54965900 0.42 IRX5
iroquois homeobox 5
179
0.97
chr1_182994808_182995119 0.42 LAMC1
laminin, gamma 1 (formerly LAMB2)
2368
0.3
chr3_112354765_112355126 0.42 CCDC80
coiled-coil domain containing 80
1999
0.4
chr12_112845239_112845416 0.42 RPL6
ribosomal protein L6
1429
0.42
chr13_76213551_76213793 0.42 LMO7
LIM domain 7
3213
0.22
chr2_238317343_238317737 0.42 COL6A3
collagen, type VI, alpha 3
5251
0.23
chr7_19151937_19152088 0.42 AC003986.6

85
0.96
chr19_30719241_30719606 0.42 ZNF536
zinc finger protein 536
2
0.73
chr9_97951408_97952029 0.42 ENSG00000238746
.
16838
0.19
chr8_59636449_59636600 0.42 ENSG00000238433
.
61621
0.12
chr14_56777613_56777829 0.42 TMEM260
transmembrane protein 260
177351
0.03
chr13_45146263_45146555 0.42 TSC22D1
TSC22 domain family, member 1
3983
0.32
chr8_62686503_62686789 0.42 ENSG00000264408
.
59299
0.14
chr5_141667234_141667739 0.42 SPRY4
sprouty homolog 4 (Drosophila)
36261
0.18
chr7_77441619_77441771 0.42 PHTF2
putative homeodomain transcription factor 2
13477
0.19
chr12_83409565_83409762 0.42 ENSG00000252220
.
6006
0.35
chr12_119617823_119618008 0.42 HSPB8
heat shock 22kDa protein 8
520
0.73
chr4_77356777_77357012 0.42 SHROOM3
shroom family member 3
641
0.68
chr6_11196915_11197406 0.41 RP3-510L9.1

23475
0.18
chr3_93691964_93692115 0.41 PROS1
protein S (alpha)
444
0.76
chr6_143896419_143896590 0.41 RP11-436I24.1

13336
0.19
chr2_151337157_151337558 0.41 RND3
Rho family GTPase 3
4539
0.37
chr3_59101471_59101696 0.41 C3orf67
chromosome 3 open reading frame 67
65773
0.15
chr20_45903102_45903304 0.41 ZMYND8
zinc finger, MYND-type containing 8
24441
0.14
chr5_39423780_39424080 0.41 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
1040
0.66

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HOXA5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.5 1.9 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.5 1.4 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.4 1.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.4 1.4 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 1.3 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 0.9 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.7 GO:0030210 heparin biosynthetic process(GO:0030210)
0.2 1.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.3 GO:0002634 regulation of germinal center formation(GO:0002634)
0.2 0.8 GO:2001280 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.2 0.4 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.2 0.7 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.4 GO:0060216 definitive hemopoiesis(GO:0060216)
0.2 0.5 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 0.7 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.7 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.2 0.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.2 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.2 1.0 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.2 0.6 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 1.1 GO:0001553 luteinization(GO:0001553)
0.2 0.6 GO:0001757 somite specification(GO:0001757)
0.2 0.6 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2 0.9 GO:0060259 regulation of feeding behavior(GO:0060259)
0.2 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.2 0.2 GO:0061299 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 0.6 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.1 0.7 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 1.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.3 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.3 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.4 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.5 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.6 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.3 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.5 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1 0.3 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.1 0.6 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.3 GO:0010667 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1 0.9 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 1.1 GO:0002040 sprouting angiogenesis(GO:0002040)
0.1 0.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.3 GO:0007132 meiotic metaphase I(GO:0007132)
0.1 0.2 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.3 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.6 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0007412 axon target recognition(GO:0007412)
0.1 0.2 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.3 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.1 0.3 GO:0031033 myosin filament organization(GO:0031033)
0.1 0.4 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.1 GO:0033088 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.1 GO:0030202 heparin metabolic process(GO:0030202)
0.1 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 0.4 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 0.3 GO:0008354 germ cell migration(GO:0008354)
0.1 0.3 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1 0.3 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.3 GO:0070091 glucagon secretion(GO:0070091)
0.1 0.3 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:0008215 spermine metabolic process(GO:0008215)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.1 1.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.1 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.2 GO:0052308 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.3 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 0.3 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.5 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 0.4 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1 0.2 GO:0060206 estrous cycle phase(GO:0060206)
0.1 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.1 GO:0051280 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.2 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 1.2 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.2 GO:0001554 luteolysis(GO:0001554)
0.1 0.1 GO:0060068 vagina development(GO:0060068)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.3 GO:0070141 response to UV-A(GO:0070141)
0.1 0.1 GO:0060437 lung growth(GO:0060437)
0.1 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.1 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.1 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.1 0.1 GO:0060347 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.1 GO:0001779 natural killer cell differentiation(GO:0001779)
0.1 0.7 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.1 0.1 GO:0072070 loop of Henle development(GO:0072070)
0.1 0.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.1 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.1 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.1 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.1 0.9 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.1 0.2 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.1 0.2 GO:0007144 female meiosis I(GO:0007144)
0.1 0.3 GO:0002076 osteoblast development(GO:0002076)
0.1 0.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 1.1 GO:0001755 neural crest cell migration(GO:0001755)
0.1 0.1 GO:0060976 coronary vasculature development(GO:0060976)
0.1 0.3 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1 0.3 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.1 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 0.2 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.2 GO:0009188 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.5 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 0.2 GO:0002118 aggressive behavior(GO:0002118)
0.1 0.1 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.7 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0014032 neural crest cell development(GO:0014032)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.5 GO:0002062 chondrocyte differentiation(GO:0002062)
0.0 0.2 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.2 GO:0001710 mesodermal cell fate commitment(GO:0001710)
0.0 1.1 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.3 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.0 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.4 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.2 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.0 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.2 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.2 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.3 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.3 GO:0007616 long-term memory(GO:0007616)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.3 GO:0099518 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0035588 adenosine receptor signaling pathway(GO:0001973) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.1 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 0.0 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.8 GO:0060606 tube closure(GO:0060606)
0.0 0.2 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.5 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0042220 response to cocaine(GO:0042220)
0.0 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0060013 righting reflex(GO:0060013)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0051931 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0019605 butyrate metabolic process(GO:0019605)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.2 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:0060405 regulation of penile erection(GO:0060405) positive regulation of penile erection(GO:0060406)
0.0 0.2 GO:0051955 regulation of amino acid transport(GO:0051955)
0.0 0.1 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0061245 establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.5 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.0 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.0 0.2 GO:0032462 regulation of protein homooligomerization(GO:0032462)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.1 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0010800 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.1 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:1903332 regulation of protein folding(GO:1903332)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0017000 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.3 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.1 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0055026 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.2 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.4 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.0 GO:0090398 cellular senescence(GO:0090398)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.2 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.0 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.1 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.1 GO:0034764 positive regulation of transmembrane transport(GO:0034764) positive regulation of ion transmembrane transport(GO:0034767)
0.0 0.1 GO:0006895 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 2.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0006188 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0051927 obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.3 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.2 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.1 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.1 GO:0044236 multicellular organism metabolic process(GO:0044236)
0.0 0.2 GO:0006949 syncytium formation(GO:0006949)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.0 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.0 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.0 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307) heart formation(GO:0060914)
0.0 0.0 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.0 0.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0018198 peptidyl-cysteine modification(GO:0018198)
0.0 0.0 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.1 GO:0007530 sex determination(GO:0007530)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.0 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.0 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.0 0.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.1 GO:0036294 cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0 0.1 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.0 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.0 0.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.0 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.0 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.0 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0046146 tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0051668 localization within membrane(GO:0051668)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.0 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.0 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.0 GO:0061140 lung secretory cell differentiation(GO:0061140)
0.0 0.0 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.0 GO:0007442 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.0 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.0 0.1 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:0090197 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.0 0.0 GO:0006167 AMP biosynthetic process(GO:0006167)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.1 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.0 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.3 GO:0051291 protein heterooligomerization(GO:0051291)
0.0 0.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.0 GO:0032634 interleukin-5 production(GO:0032634) regulation of interleukin-5 production(GO:0032674)
0.0 0.0 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.0 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.0 0.0 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0046037 GMP metabolic process(GO:0046037)
0.0 0.1 GO:0006825 copper ion transport(GO:0006825)
0.0 0.0 GO:0007143 female meiotic division(GO:0007143)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.3 2.9 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.5 GO:0048179 activin receptor complex(GO:0048179)
0.2 0.5 GO:0043260 laminin-11 complex(GO:0043260)
0.2 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0071437 invadopodium(GO:0071437)
0.1 0.1 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.4 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.7 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.3 GO:0032059 bleb(GO:0032059)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.2 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0044304 main axon(GO:0044304)
0.1 0.5 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.4 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.1 GO:0042588 zymogen granule(GO:0042588)
0.1 0.2 GO:0030904 retromer complex(GO:0030904)
0.1 0.3 GO:0016342 catenin complex(GO:0016342)
0.1 0.3 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.1 0.3 GO:0005581 collagen trimer(GO:0005581)
0.1 0.3 GO:0030673 axolemma(GO:0030673)
0.1 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0043205 fibril(GO:0043205)
0.1 2.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 0.4 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 1.4 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 9.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.3 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.7 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 2.7 GO:0030055 cell-substrate adherens junction(GO:0005924) cell-substrate junction(GO:0030055)
0.0 0.3 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 1.3 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.5 GO:0030286 dynein complex(GO:0030286)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.1 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0042597 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.0 GO:0044447 axoneme part(GO:0044447)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.3 GO:0030118 clathrin coat(GO:0030118)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 3.7 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 1.4 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.2 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:0005912 adherens junction(GO:0005912)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0043073 germ cell nucleus(GO:0043073)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.3 GO:0030018 Z disc(GO:0030018)
0.0 0.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 6.6 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.1 GO:0048495 Roundabout binding(GO:0048495)
0.3 1.8 GO:0043274 phospholipase binding(GO:0043274)
0.3 0.8 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.2 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 1.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 0.5 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.2 0.9 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 1.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.8 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.5 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 4.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.5 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.1 1.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.3 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 1.0 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.4 GO:0005497 androgen binding(GO:0005497)
0.1 0.5 GO:0042805 actinin binding(GO:0042805)
0.1 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.5 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.1 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.6 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 0.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1 0.4 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.1 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.9 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.4 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 1.0 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.3 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.1 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 0.5 GO:0051378 serotonin binding(GO:0051378)
0.1 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.2 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.2 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.5 GO:0030553 cGMP binding(GO:0030553)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.3 GO:0031419 cobalamin binding(GO:0031419)
0.0 1.0 GO:0046332 SMAD binding(GO:0046332)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0032052 bile acid binding(GO:0032052)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0070700 transmembrane receptor protein serine/threonine kinase binding(GO:0070696) BMP receptor binding(GO:0070700)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.3 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.3 GO:0043394 proteoglycan binding(GO:0043394) heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0035514 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.5 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.0 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0016715 dopamine beta-monooxygenase activity(GO:0004500) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.5 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.6 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0004946 bombesin receptor activity(GO:0004946)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.0 GO:0052659 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.0 GO:0051636 obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.4 GO:0044212 regulatory region DNA binding(GO:0000975) regulatory region nucleic acid binding(GO:0001067) transcription regulatory region DNA binding(GO:0044212)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 2.3 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.0 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 2.8 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0004180 carboxypeptidase activity(GO:0004180)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 5.1 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 0.1 PID INSULIN PATHWAY Insulin Pathway
0.1 0.7 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 5.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 1.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.4 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 4.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID AURORA A PATHWAY Aurora A signaling
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.3 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.2 6.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.6 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.1 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 1.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.6 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 2.3 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 0.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions