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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXB3

Z-value: 1.06

Motif logo

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Transcription factors associated with HOXB3

Gene Symbol Gene ID Gene Info
HOXB3
ENSG00000120093.7 homeobox B3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr17_46643320_46643471HOXB379900.0720510.771.6e-02Click!
chr17_46650833_46651193HOXB33720.6747420.599.8e-02Click!
chr17_46633195_46633347HOXB36120.441121-0.521.5e-01Click!
chr17_46665362_46665513HOXB321600.112807-0.511.6e-01Click!
chr17_46653822_46653973HOXB314590.174654-0.472.0e-01Click!

Activity of the HOXB3 motif across conditions

Conditions sorted by the z-value of the HOXB3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_64864648_64864996 0.52 SERTAD2
 SERTA domain containing 2
 16225
 0.22
chr11_128582862_128583013 0.51 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 17019
 0.17
chr5_147836900_147837051 0.50 CTD-2283N19.1
26605
 0.18
chr20_45946936_45948261 0.47 AL031666.2
 HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
 352
 0.82
chr1_198238845_198238996 0.42 NEK7
 NIMA-related kinase 7
 48991
 0.19
chr3_145879077_145879748 0.41 PLOD2
 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
 458
 0.86
chr2_227516189_227516445 0.40 ENSG00000263363
 .
 7192
 0.31
chr3_195273446_195273682 0.39 AC091633.3
145
 0.95
chr2_128492018_128492224 0.39 SFT2D3
 SFT2 domain containing 3
 33524
 0.13
chr2_153267501_153267713 0.39 FMNL2
 formin-like 2
 75856
 0.12
chr1_68697735_68698156 0.36 WLS
 wntless Wnt ligand secretion mediator
 18
 0.98
chr8_57517628_57517779 0.36 RP11-17A4.2
116046
 0.06
chr13_32828572_32828723 0.36 FRY
 furry homolog (Drosophila)
 10158
 0.21
chr1_151918063_151918251 0.36 THEM4
 thioesterase superfamily member 4
 35873
 0.1
chr7_151048885_151049126 0.36 NUB1
 negative regulator of ubiquitin-like proteins 1
 6574
 0.16
chr20_14316163_14316462 0.35 FLRT3
 fibronectin leucine rich transmembrane protein 3
 1942
 0.4
chr14_65192350_65192501 0.35 PLEKHG3
 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
 1926
 0.38
chr10_12746098_12746480 0.35 ENSG00000221331
 .
 21063
 0.25
chr2_63275452_63275960 0.35 AC009501.4
50
 0.97
chr9_113800702_113801367 0.35 LPAR1
 lysophosphatidic acid receptor 1
 53
 0.98
chr4_169756047_169756198 0.34 RP11-635L1.3
2034
 0.31
chr21_34398214_34398768 0.34 OLIG2
 oligodendrocyte lineage transcription factor 2
 248
 0.93
chr1_84107245_84107582 0.34 ENSG00000223231
 .
 152147
 0.04
chr1_87799796_87800719 0.34 LMO4
 LIM domain only 4
 2906
 0.4
chr7_129933276_129933885 0.33 CPA4
 carboxypeptidase A4
 461
 0.76
chr4_40630076_40630227 0.33 RBM47
 RNA binding motif protein 47
 1730
 0.47
chr1_88180949_88181100 0.33 ENSG00000199318
 .
 261968
 0.02
chr9_18976648_18977105 0.33 FAM154A
 family with sequence similarity 154, member A
 56310
 0.1
chr5_142284312_142284613 0.33 ARHGAP26
 Rho GTPase activating protein 26
 2425
 0.38
chr17_64187141_64188685 0.33 CEP112
 centrosomal protein 112kDa
 60
 0.98
chr4_95367292_95367585 0.32 PDLIM5
 PDZ and LIM domain 5
 5599
 0.33
chr7_105912156_105912307 0.32 NAMPT
 nicotinamide phosphoribosyltransferase
 13136
 0.21
chr4_142380005_142380156 0.32 ENSG00000238695
 .
 161048
 0.04
chr18_33554456_33554607 0.31 C18orf21
 chromosome 18 open reading frame 21
 1783
 0.36
chr6_16737749_16737900 0.31 RP1-151F17.1
23545
 0.22
chr7_27153769_27154326 0.31 HOXA-AS2
 HOXA cluster antisense RNA 2
 492
 0.41
chr12_58705170_58705321 0.31 RP11-362K2.2
 Protein LOC100506869
 232662
 0.02
chr8_116675050_116675578 0.31 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr5_3597777_3597928 0.31 IRX1
 iroquois homeobox 1
 1684
 0.41
chr10_119303944_119304573 0.30 EMX2OS
 EMX2 opposite strand/antisense RNA
 321
 0.88
chr13_50706829_50707141 0.30 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 50678
 0.13
chr14_100573958_100574109 0.30 ENSG00000265154
 .
 1818
 0.23
chr4_139635357_139635508 0.30 ENSG00000238971
 .
 97488
 0.08
chr19_38494188_38494741 0.30 CTC-244M17.1
39971
 0.13
chr17_30683527_30683678 0.30 ZNF207
 zinc finger protein 207
 5675
 0.15
chr4_160357796_160357947 0.30 ENSG00000251979
 .
 70309
 0.12
chr20_11887627_11887778 0.30 BTBD3
 BTB (POZ) domain containing 3
 10863
 0.23
chr21_40357766_40357986 0.30 ENSG00000272015
 .
 91167
 0.09
chr12_50748152_50748528 0.30 FAM186A
 family with sequence similarity 186, member A
 3672
 0.22
chr15_96878987_96879612 0.29 ENSG00000222651
 .
 2809
 0.21
chr2_26100038_26101197 0.29 ASXL2
 additional sex combs like 2 (Drosophila)
 718
 0.76
chr2_207998546_207999225 0.29 KLF7
 Kruppel-like factor 7 (ubiquitous)
 24
 0.98
chr6_137544605_137544818 0.29 IFNGR1
 interferon gamma receptor 1
 4125
 0.31
chr18_46620789_46620940 0.29 DYM
 dymeclin
 2999
 0.26
chr18_27841796_27841947 0.29 ENSG00000251702
 .
 722201
 0.0
chr9_17578628_17579355 0.29 SH3GL2
 SH3-domain GRB2-like 2
 130
 0.98
chr11_57530814_57530965 0.29 CTNND1
 catenin (cadherin-associated protein), delta 1
 436
 0.77
chr5_35309735_35309886 0.29 PRLR
 prolactin receptor
 79016
 0.1
chr12_32635785_32635936 0.29 FGD4
 FYVE, RhoGEF and PH domain containing 4
 3046
 0.28
chr5_119820967_119821118 0.29 PRR16
 proline rich 16
 19716
 0.29
chr16_13401641_13401792 0.28 AC003009.1
24724
 0.26
chr12_94132438_94132603 0.28 RP11-887P2.5
921
 0.64
chr21_36254420_36254945 0.28 RUNX1
 runt-related transcription factor 1
 4798
 0.34
chr22_19073564_19073715 0.28 AC004471.9
35403
 0.09
chr16_17931379_17931530 0.28 XYLT1
 xylosyltransferase I
 366716
 0.01
chr3_108988766_108988917 0.28 ENSG00000252889
 .
 44865
 0.15
chr7_37724366_37724517 0.28 GPR141
 G protein-coupled receptor 141
 966
 0.42
chr12_89032903_89033122 0.28 ENSG00000252850
 .
 57596
 0.14
chr7_32102480_32102631 0.28 PDE1C
 phosphodiesterase 1C, calmodulin-dependent 70kDa
 7906
 0.33
chr6_50378521_50378672 0.28 TFAP2D
 transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
 302945
 0.01
chr3_151560621_151560772 0.27 AADAC
 arylacetamide deacetylase
 28835
 0.17
chr10_81026521_81026806 0.27 ZMIZ1
 zinc finger, MIZ-type containing 1
 39312
 0.18
chr16_86619409_86619937 0.27 FOXL1
 forkhead box L1
 7558
 0.18
chr3_134050593_134051228 0.27 AMOTL2
 angiomotin like 2
 39844
 0.16
chr1_196577911_196578299 0.27 KCNT2
 potassium channel, subfamily T, member 2
 250
 0.94
chr3_33318777_33319866 0.27 FBXL2
 F-box and leucine-rich repeat protein 2
 353
 0.91
chr11_74292413_74292564 0.27 POLD3
 polymerase (DNA-directed), delta 3, accessory subunit
 11087
 0.2
chr3_69434805_69435778 0.27 FRMD4B
 FERM domain containing 4B
 67
 0.99
chr10_4170534_4170685 0.27 KLF6
 Kruppel-like factor 6
 343136
 0.01
chr2_58266503_58266768 0.27 VRK2
 vaccinia related kinase 2
 7094
 0.27
chr1_95330057_95330663 0.27 SLC44A3
 solute carrier family 44, member 3
 2527
 0.28
chr15_43985556_43986365 0.27 CKMT1A
 creatine kinase, mitochondrial 1A
 109
 0.93
chr1_52605764_52605957 0.27 ZFYVE9
 zinc finger, FYVE domain containing 9
 2186
 0.28
chr18_45480065_45480352 0.27 SMAD2
 SMAD family member 2
 22693
 0.23
chr4_89714293_89714444 0.27 FAM13A
 family with sequence similarity 13, member A
 29984
 0.19
chr12_46949518_46949939 0.26 SLC38A2
 solute carrier family 38, member 2
 183078
 0.03
chr1_225842736_225843127 0.26 ENAH
 enabled homolog (Drosophila)
 2087
 0.34
chr2_191624663_191624826 0.26 AC006460.2
51302
 0.14
chr19_58488964_58489115 0.26 C19orf18
 chromosome 19 open reading frame 18
 3137
 0.15
chr10_75668708_75669249 0.26 PLAU
 plasminogen activator, urokinase
 43
 0.97
chr13_76026824_76027007 0.26 TBC1D4
 TBC1 domain family, member 4
 29335
 0.19
chr3_168240363_168240514 0.26 ENSG00000207717
 .
 29204
 0.22
chr2_195207760_195207911 0.26 ENSG00000264560
 .
 215163
 0.02
chr2_197103959_197104132 0.26 AC020571.3
20703
 0.17
chr5_159524987_159525138 0.26 PWWP2A
 PWWP domain containing 2A
 21367
 0.17
chrX_41379072_41379223 0.26 CASK-AS1
 CASK antisense RNA 1
 142
 0.96
chr9_20490881_20491032 0.26 ENSG00000264941
 .
 11384
 0.23
chr12_46759532_46760006 0.26 SLC38A2
 solute carrier family 38, member 2
 679
 0.75
chr6_58148368_58148782 0.26 ENSG00000212017
 .
 893645
 0.0
chr10_33798417_33798757 0.25 NRP1
 neuropilin 1
 173397
 0.03
chr3_65949778_65949974 0.25 MAGI1-IT1
 MAGI1 intronic transcript 1 (non-protein coding)
 9643
 0.19
chr12_65700600_65700821 0.25 MSRB3
 methionine sulfoxide reductase B3
 19945
 0.21
chr19_30436184_30436558 0.25 URI1
 URI1, prefoldin-like chaperone
 2946
 0.39
chr1_209975427_209975724 0.25 IRF6
 interferon regulatory factor 6
 64
 0.96
chr12_18414636_18414918 0.25 PIK3C2G
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
 303
 0.95
chr12_115135696_115136278 0.25 TBX3
 T-box 3
 14018
 0.21
chr22_38723559_38723988 0.25 CSNK1E
 casein kinase 1, epsilon
 9684
 0.15
chr20_10502111_10502382 0.25 SLX4IP
 SLX4 interacting protein
 86295
 0.09
chr3_108553094_108553245 0.25 TRAT1
 T cell receptor associated transmembrane adaptor 1
 11550
 0.26
chr12_106699376_106699527 0.25 CKAP4
 cytoskeleton-associated protein 4
 1394
 0.34
chrX_11456470_11456766 0.25 ARHGAP6
 Rho GTPase activating protein 6
 10725
 0.3
chr10_45389082_45389233 0.25 TMEM72
 transmembrane protein 72
 17491
 0.16
chr11_33466056_33466207 0.25 ENSG00000223134
 .
 90120
 0.08
chr3_9006349_9006500 0.25 RAD18
 RAD18 homolog (S. cerevisiae)
 967
 0.6
chr2_103506378_103506656 0.25 TMEM182
 transmembrane protein 182
 128045
 0.06
chr18_77385131_77385282 0.25 CTDP1
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
 54595
 0.14
chr16_3911841_3912078 0.25 CREBBP
 CREB binding protein
 18162
 0.21
chr15_79172438_79172758 0.25 MORF4L1
 mortality factor 4 like 1
 2016
 0.31
chr12_51640112_51640647 0.25 DAZAP2
 DAZ associated protein 2
 7300
 0.14
chr4_47544899_47545050 0.25 AC092597.3
17302
 0.23
chr1_3736530_3736681 0.25 CEP104
 centrosomal protein 104kDa
 9265
 0.12
chr8_79260999_79261150 0.25 ENSG00000252935
 .
 49783
 0.19
chr7_83932213_83932364 0.25 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 107527
 0.08
chr2_176709130_176709424 0.25 AC016751.3
52787
 0.15
chr2_158039761_158039912 0.25 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 74274
 0.11
chr19_53716573_53716772 0.24 ZNF665
 zinc finger protein 665
 20045
 0.1
chrX_64908310_64908461 0.24 MSN
 moesin
 20848
 0.28
chr6_139292312_139292463 0.24 REPS1
 RALBP1 associated Eps domain containing 1
 16390
 0.23
chr10_114714851_114715858 0.24 RP11-57H14.2
3720
 0.26
chr4_177931414_177931624 0.24 ENSG00000222859
 .
 171077
 0.03
chr7_123390243_123390394 0.24 RP11-390E23.6
1196
 0.34
chr5_14153831_14154379 0.24 TRIO
 trio Rho guanine nucleotide exchange factor
 10276
 0.32
chr8_41165312_41165463 0.24 SFRP1
 secreted frizzled-related protein 1
 878
 0.57
chr6_133066944_133067095 0.24 RP1-55C23.7
6795
 0.13
chr5_77886889_77887187 0.24 LHFPL2
 lipoma HMGIC fusion partner-like 2
 42064
 0.21
chr15_43885730_43886468 0.24 CKMT1B
 creatine kinase, mitochondrial 1B
 42
 0.95
chr2_158113918_158114875 0.24 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 286
 0.93
chr10_33422709_33422860 0.24 ENSG00000263576
 .
 35220
 0.17
chr19_39143944_39144135 0.24 ACTN4
 actinin, alpha 4
 5661
 0.13
chr13_40858172_40858323 0.24 ENSG00000207458
 .
 57283
 0.16
chr1_51069078_51069376 0.24 FAF1
 Fas (TNFRSF6) associated factor 1
 8943
 0.23
chr8_49612409_49612560 0.24 EFCAB1
 EF-hand calcium binding domain 1
 29864
 0.25
chr10_31273151_31273302 0.24 ZNF438
 zinc finger protein 438
 129
 0.98
chr6_157381110_157381404 0.24 RP1-137K2.2
59583
 0.15
chr2_228735999_228736581 0.23 DAW1
 dynein assembly factor with WDR repeat domains 1
 33
 0.98
chr11_22724799_22724998 0.23 ENSG00000222427
 .
 15001
 0.2
chr20_56749874_56750278 0.23 C20orf85
 chromosome 20 open reading frame 85
 24116
 0.19
chr15_82414957_82415108 0.23 RP11-597K23.2
 Uncharacterized protein
 34000
 0.16
chr13_37397601_37397752 0.23 RFXAP
 regulatory factor X-associated protein
 4315
 0.24
chr20_52370901_52371111 0.23 ENSG00000238468
 .
 85709
 0.09
chr1_202438325_202438476 0.23 PPP1R12B
 protein phosphatase 1, regulatory subunit 12B
 6529
 0.23
chr13_100860702_100860853 0.23 PCCA
 propionyl CoA carboxylase, alpha polypeptide
 84701
 0.1
chr2_188360675_188360826 0.23 TFPI
 tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
 17618
 0.23
chr4_156590981_156591132 0.23 GUCY1A3
 guanylate cyclase 1, soluble, alpha 3
 2241
 0.4
chr4_114705923_114706074 0.23 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 22915
 0.27
chr17_33391542_33391948 0.23 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
 874
 0.45
chr3_162506552_162506703 0.23 ENSG00000238398
 .
 390136
 0.01
chr12_78336292_78336638 0.23 NAV3
 neuron navigator 3
 23591
 0.28
chr20_35924690_35924841 0.23 MANBAL
 mannosidase, beta A, lysosomal-like
 534
 0.79
chr18_55891591_55891981 0.23 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 2983
 0.31
chr8_57086542_57086822 0.23 PLAG1
 pleiomorphic adenoma gene 1
 37156
 0.12
chr2_147107195_147107346 0.23 ENSG00000251905
 .
 204546
 0.03
chr9_79483882_79484033 0.23 PRUNE2
 prune homolog 2 (Drosophila)
 37044
 0.21
chr1_200987607_200987758 0.23 KIF21B
 kinesin family member 21B
 4854
 0.21
chr1_181069341_181069492 0.23 IER5
 immediate early response 5
 11778
 0.23
chr5_123252700_123253101 0.23 CSNK1G3
 casein kinase 1, gamma 3
 328781
 0.01
chr6_83094369_83094520 0.22 TPBG
 trophoblast glycoprotein
 20483
 0.28
chr6_1614659_1614953 0.22 FOXC1
 forkhead box C1
 4125
 0.35
chr2_195590152_195590303 0.22 ENSG00000252517
 .
 61329
 0.16
chr7_92254665_92254816 0.22 FAM133B
 family with sequence similarity 133, member B
 35032
 0.17
chr21_19152947_19153098 0.22 AL109761.5
12783
 0.23
chr4_15963408_15963559 0.22 FGFBP2
 fibroblast growth factor binding protein 2
 1376
 0.42
chr12_96094020_96094171 0.22 ENSG00000212448
 .
 82630
 0.07
chr12_27901688_27901839 0.22 ENSG00000252585
 .
 4044
 0.14
chr5_73839186_73839374 0.22 HEXB
 hexosaminidase B (beta polypeptide)
 96568
 0.07
chr15_30112674_30113382 0.22 TJP1
 tight junction protein 1
 723
 0.64
chr4_48240161_48240435 0.22 TEC
 tec protein tyrosine kinase
 31583
 0.18
chr7_93003610_93003782 0.22 CCDC132
 coiled-coil domain containing 132
 24486
 0.23
chr7_115670709_115671033 0.22 TFEC
 transcription factor EC
 4
 0.99
chr4_459906_460057 0.22 ENSG00000252150
 .
 1444
 0.36
chr5_17223836_17223987 0.22 BASP1
 brain abundant, membrane attached signal protein 1
 6242
 0.19
chr4_141984739_141984890 0.22 RNF150
 ring finger protein 150
 9934
 0.3
chr2_43822335_43823890 0.22 THADA
 thyroid adenoma associated
 1
 0.98
chr1_189407105_189407256 0.22 ENSG00000252553
 .
 228206
 0.02
chr17_39742070_39742221 0.22 KRT14
 keratin 14
 1028
 0.36
chr5_73536836_73537130 0.22 ENSG00000222551
 .
 30607
 0.23
chrX_39548256_39548819 0.22 ENSG00000263730
 .
 28067
 0.24
chr9_96819103_96819334 0.22 PTPDC1
 protein tyrosine phosphatase domain containing 1
 26142
 0.21
chr15_71606160_71606311 0.22 RP11-592N21.2
28428
 0.23
chr7_38546645_38546796 0.22 ENSG00000241756
 .
 24219
 0.23
chr11_128453017_128453335 0.22 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4277
 0.28
chr15_34875013_34876331 0.22 GOLGA8B
 golgin A8 family, member B
 99
 0.96
chr6_7727536_7728016 0.22 BMP6
 bone morphogenetic protein 6
 746
 0.78
chr13_52108240_52108391 0.22 INTS6-AS1
 INTS6 antisense RNA 1
 7379
 0.15
chr10_79470838_79471281 0.22 ENSG00000199664
 .
 65754
 0.1
chr22_46436012_46436163 0.22 RP6-109B7.5
12886
 0.1
chrX_95690881_95691032 0.22 ENSG00000223260
 .
 25175
 0.28
chr4_88817282_88817552 0.22 MEPE
 matrix extracellular phosphoglycoprotein
 63278
 0.1
chr3_71591333_71591803 0.21 ENSG00000221264
 .
 328
 0.83
chr9_89952337_89952906 0.21 ENSG00000212421
 .
 77256
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.1 0.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.2 GO:0032344 regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1 0.2 GO:1900115 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.3 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1 0.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.0 0.2 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0043931 ossification involved in bone maturation(GO:0043931)
0.0 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0071224 cellular response to peptidoglycan(GO:0071224)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0052169 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.2 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.0 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.1 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0010159 specification of organ position(GO:0010159)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 0.2 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of cell junction assembly(GO:1901889) negative regulation of adherens junction organization(GO:1903392)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.1 GO:0021978 telencephalon regionalization(GO:0021978)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.2 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0060292 long term synaptic depression(GO:0060292)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.0 GO:0032328 alanine transport(GO:0032328)
0.0 0.0 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0060677 ureteric bud elongation(GO:0060677)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991)
0.0 0.1 GO:0010665 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0003160 endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0 0.3 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.0 GO:0002604 dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0001946 lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.0 GO:0033860 regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.0 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.1 GO:0032801 receptor catabolic process(GO:0032801)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.0 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.0 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.0 0.1 GO:0072666 protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0 0.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.0 GO:0045425 interleukin-3 production(GO:0032632) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.0 0.0 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.0 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.0 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.2 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.0 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.0 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.0 GO:1902745 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.0 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.0 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.0 0.0 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0031268 pseudopodium organization(GO:0031268)
0.0 0.0 GO:0048505 regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0 0.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.2 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.0 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0043256 laminin complex(GO:0043256)
0.0 0.2 GO:0099738 cell cortex region(GO:0099738)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.1 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.4 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.3 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.2 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0051378 serotonin binding(GO:0051378)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0050543 icosatetraenoic acid binding(GO:0050543) arachidonic acid binding(GO:0050544)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0071553 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.0 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.0 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.0 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0048019 receptor antagonist activity(GO:0048019)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.0 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.1 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.6 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.0 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis