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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXB4_LHX9

Z-value: 1.21

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Transcription factors associated with HOXB4_LHX9

Gene Symbol	Gene ID	Gene Info
HOXB4 Ensembl NCBI GeneCards UniProt	ENSG00000182742.5	homeobox B4
LHX9 Ensembl NCBI GeneCards UniProt	ENSG00000143355.11	LIM homeobox 9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_46658327_46658478	HOXB4	929	0.236935	0.41	2.8e-01	Click!
chr17_46658149_46658300	HOXB4	751	0.289329	-0.23	5.5e-01	Click!
chr17_46657344_46657617	HOXB4	7	0.648893	0.15	7.0e-01	Click!
chr1_197879409_197879560	LHX9	2137	0.365782	0.70	3.5e-02	Click!
chr1_197999710_197999861	LHX9	113256	0.063457	0.69	4.0e-02	Click!
chr1_197877951_197878134	LHX9	3579	0.278863	0.68	4.3e-02	Click!
chr1_197885056_197885605	LHX9	363	0.900744	0.56	1.1e-01	Click!
chr1_197880988_197881139	LHX9	558	0.809868	0.53	1.4e-01	Click!

Activity of the HOXB4_LHX9 motif across conditions

Conditions sorted by the z-value of the HOXB4_LHX9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_129933276_129933885	2.13	CPA4	carboxypeptidase A4	461	0.76
chr4_157891142_157892336	1.98	PDGFC	platelet derived growth factor C	316	0.91
chr9_18474095_18474958	1.68	ADAMTSL1	ADAMTS-like 1	295	0.95
chr7_17720120_17720505	1.61	SNX13	sorting nexin 13	259779	0.02
chr15_96878987_96879612	1.45	ENSG00000222651	.	2809	0.21
chr1_87799796_87800719	1.35	LMO4	LIM domain only 4	2906	0.4
chr1_225839301_225840394	1.16	ENAH	enabled homolog (Drosophila)	571	0.78
chr3_87036535_87037613	1.12	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr18_53089837_53090372	1.10	TCF4	transcription factor 4	361	0.89
chr12_115135696_115136278	1.08	TBX3	T-box 3	14018	0.21
chr20_37614039_37614271	1.06	DHX35	DEAH (Asp-Glu-Ala-His) box polypeptide 35	23168	0.18
chr7_92327766_92328157	1.05	ENSG00000206763	.	3167	0.33
chr9_89952337_89952906	0.99	ENSG00000212421	.	77256	0.11
chr3_33318777_33319866	0.97	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr21_17909068_17909746	0.97	ENSG00000207638	.	2002	0.33
chr10_69831641_69832005	0.97	HERC4	HECT and RLD domain containing E3 ubiquitin protein ligase 4	2071	0.33
chr16_4424352_4424847	0.95	VASN	vasorin	2750	0.17
chr4_141015619_141015856	0.95	RP11-392B6.1		33432	0.2
chr3_114477857_114478359	0.95	ZBTB20	zinc finger and BTB domain containing 20	10	0.99
chr11_131780111_131780399	0.92	NTM	neurotrimin	642	0.77
chr18_53090404_53090609	0.92	TCF4	transcription factor 4	763	0.7
chrX_114829080_114829277	0.91	PLS3	plastin 3	1313	0.48
chr3_79066759_79066910	0.91	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	860	0.75
chr4_89977525_89978081	0.91	FAM13A	family with sequence similarity 13, member A	508	0.85
chr4_77506894_77507309	0.91	ENSG00000265314	.	10397	0.17
chr13_76217437_76217800	0.90	LMO7	LIM domain 7	7159	0.18
chr4_134070427_134071051	0.90	PCDH10	protocadherin 10	269	0.96
chr16_62068318_62068835	0.89	CDH8	cadherin 8, type 2	462	0.9
chr3_88191159_88191414	0.89	ZNF654	zinc finger protein 654	3032	0.24
chr21_36254420_36254945	0.87	RUNX1	runt-related transcription factor 1	4798	0.34
chr1_68697735_68698156	0.87	WLS	wntless Wnt ligand secretion mediator	18	0.98
chr10_24754741_24755189	0.87	KIAA1217	KIAA1217	495	0.84
chr1_31480017_31480289	0.86	PUM1	pumilio RNA-binding family member 1	12202	0.19
chr7_95402477_95402695	0.86	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	670	0.81
chr11_106239153_106239583	0.85	RP11-680E19.1		104326	0.08
chr11_27740250_27740471	0.84	BDNF	brain-derived neurotrophic factor	934	0.68
chr6_85823864_85824548	0.84	NT5E	5'-nucleotidase, ecto (CD73)	335603	0.01
chr7_98970111_98970529	0.84	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	1552	0.28
chr8_89311514_89311910	0.83	RP11-586K2.1		27353	0.2
chr12_66286178_66286489	0.83	RP11-366L20.2	Uncharacterized protein	10386	0.18
chr10_4285552_4285907	0.82	ENSG00000207124	.	271415	0.02
chr1_243415347_243415602	0.82	CEP170	centrosomal protein 170kDa	1148	0.47
chr3_134050593_134051228	0.82	AMOTL2	angiomotin like 2	39844	0.16
chr2_207998546_207999225	0.81	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr8_116675050_116675578	0.80	TRPS1	trichorhinophalangeal syndrome I	1409	0.6
chr8_127837007_127837644	0.79	ENSG00000212451	.	153558	0.04
chr9_16726683_16727481	0.79	RP11-62F24.2		270	0.85
chr20_10521227_10521501	0.79	SLX4IP	SLX4 interacting protein	105413	0.06
chr6_27060216_27060434	0.79	ENSG00000222800	.	17434	0.13
chr15_88020923_88021173	0.78	ENSG00000207150	.	3528	0.4
chr18_60385543_60385694	0.78	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	2935	0.28
chr4_107956832_107957922	0.78	DKK2	dickkopf WNT signaling pathway inhibitor 2	77	0.99
chr3_79216626_79216907	0.76	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	148157	0.05
chr12_89845524_89845923	0.75	POC1B	POC1 centriolar protein B	45311	0.13
chr15_97778812_97779147	0.75	ENSG00000242863	.	117748	0.06
chr12_50665639_50665877	0.74	LIMA1	LIM domain and actin binding 1	11509	0.13
chr2_46933523_46933944	0.74	SOCS5	suppressor of cytokine signaling 5	7407	0.22
chr5_120114861_120115414	0.74	ENSG00000222609	.	68602	0.14
chr15_30112674_30113382	0.74	TJP1	tight junction protein 1	723	0.64
chr8_37350646_37351319	0.74	RP11-150O12.6		23557	0.24
chr2_157657104_157657488	0.73	ENSG00000263848	.	214473	0.02
chr7_24988449_24988600	0.72	OSBPL3	oxysterol binding protein-like 3	30812	0.21
chr1_45083000_45083241	0.72	RNF220	ring finger protein 220	8878	0.17
chr6_163817634_163818149	0.72	QKI	QKI, KH domain containing, RNA binding	17784	0.29
chr12_47470653_47470804	0.72	PCED1B	PC-esterase domain containing 1B	2658	0.29
chr2_3626466_3626991	0.71	ENSG00000252531	.	1432	0.27
chr2_197831667_197831951	0.71	ANKRD44	ankyrin repeat domain 44	33417	0.18
chr6_5471426_5471612	0.70	RP1-232P20.1		13211	0.27
chr3_114404388_114404544	0.70	ENSG00000264623	.	57906	0.14
chr8_30243504_30243875	0.70	RBPMS-AS1	RBPMS antisense RNA 1	772	0.48
chr3_59101471_59101696	0.69	C3orf67	chromosome 3 open reading frame 67	65773	0.15
chr5_92908415_92908864	0.69	ENSG00000237187	.	1590	0.42
chr9_12859535_12860149	0.69	ENSG00000222658	.	25478	0.2
chr7_157140270_157140421	0.68	DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	7830	0.25
chr8_93114852_93115389	0.68	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	334	0.94
chr20_46412966_46413363	0.68	SULF2	sulfatase 2	1069	0.59
chr1_234635711_234635917	0.67	TARBP1	TAR (HIV-1) RNA binding protein 1	20965	0.2
chr5_82767889_82768074	0.67	VCAN	versican	237	0.96
chr1_236073367_236073780	0.67	ENSG00000206803	.	5142	0.2
chr8_56805751_56805987	0.67	RP11-318K15.2		285	0.88
chr4_77611462_77611724	0.66	AC107072.2		52817	0.12
chr12_94580963_94581249	0.66	RP11-74K11.2		1286	0.5
chr12_56917781_56918152	0.66	RBMS2	RNA binding motif, single stranded interacting protein 2	2183	0.23
chr18_52495652_52496658	0.66	RAB27B	RAB27B, member RAS oncogene family	725	0.77
chr12_120246427_120246712	0.66	CIT	citron (rho-interacting, serine/threonine kinase 21)	5382	0.27
chr12_80081544_80081908	0.66	PAWR	PRKC, apoptosis, WT1, regulator	2134	0.41
chr1_68214173_68214559	0.65	ENSG00000238778	.	23970	0.19
chr11_111849006_111849202	0.64	DIXDC1	DIX domain containing 1	1071	0.39
chr15_99788624_99789059	0.64	TTC23	tetratricopeptide repeat domain 23	895	0.51
chr4_108746841_108747185	0.64	SGMS2	sphingomyelin synthase 2	649	0.76
chr5_173000019_173000195	0.63	CTB-33O18.3		6539	0.26
chr9_126331371_126331654	0.63	ENSG00000222722	.	16224	0.24
chr4_128459981_128460192	0.63	INTU	inturned planar cell polarity protein	84340	0.11
chr8_97507706_97507857	0.63	SDC2	syndecan 2	1545	0.51
chr4_6887879_6888223	0.63	TBC1D14	TBC1 domain family, member 14	22918	0.18
chr4_140808579_140808865	0.63	MAML3	mastermind-like 3 (Drosophila)	2484	0.4
chr3_114169976_114170457	0.62	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr9_100069620_100070257	0.62	CCDC180	coiled-coil domain containing 180	3	0.98
chr9_130615060_130615211	0.62	ENG	endoglin	1780	0.16
chr3_110791913_110792064	0.62	PVRL3	poliovirus receptor-related 3	973	0.53
chr18_42313149_42313495	0.62	SETBP1	SET binding protein 1	36193	0.24
chr1_63212144_63212320	0.62	ATG4C	autophagy related 4C, cysteine peptidase	37574	0.17
chr6_27182410_27182602	0.62	PRSS16	protease, serine, 16 (thymus)	32974	0.13
chr4_79473579_79473973	0.62	ANXA3	annexin A3	655	0.79
chr10_62331691_62331925	0.61	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	613	0.85
chr13_24146066_24146217	0.61	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1338	0.59
chr13_73081776_73081993	0.61	ENSG00000251715	.	47145	0.15
chr12_49581087_49581445	0.61	TUBA1A	tubulin, alpha 1a	25	0.96
chr4_124339424_124339730	0.61	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	18454	0.3
chr3_172035927_172036370	0.60	AC092964.1	Uncharacterized protein	1930	0.38
chr2_242605024_242605218	0.60	ATG4B	autophagy related 4B, cysteine peptidase	890	0.44
chr9_22008020_22008450	0.60	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	717	0.61
chr4_183370400_183371073	0.60	TENM3	teneurin transmembrane protein 3	584	0.84
chr7_70201396_70202343	0.60	AUTS2	autism susceptibility candidate 2	7744	0.34
chr3_105657205_105657471	0.60	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	68942	0.15
chr11_114167823_114168031	0.60	NNMT	nicotinamide N-methyltransferase	158	0.96
chr8_48648492_48649280	0.60	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	2762	0.26
chr20_50384318_50384901	0.60	ATP9A	ATPase, class II, type 9A	258	0.94
chr7_30202699_30202958	0.59	AC007036.5		5681	0.19
chr18_20612011_20612377	0.59	ENSG00000223023	.	7635	0.17
chr1_28390431_28390759	0.58	EYA3	eyes absent homolog 3 (Drosophila)	5997	0.17
chr11_12849556_12849989	0.58	RP11-47J17.3		4558	0.23
chr17_19998529_19998923	0.58	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	279	0.92
chr1_25525114_25525400	0.58	RP4-706G24.1		9373	0.19
chr15_96869332_96869483	0.58	NR2F2	nuclear receptor subfamily 2, group F, member 2	240	0.83
chr8_25868117_25868310	0.58	EBF2	early B-cell factor 2	30791	0.24
chr1_186588107_186588258	0.58	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	61377	0.14
chr19_30719241_30719606	0.58	ZNF536	zinc finger protein 536	2	0.73
chr1_179111271_179111703	0.58	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr11_126870778_126870987	0.58	KIRREL3	kin of IRRE like 3 (Drosophila)	176	0.93
chr6_143193241_143193570	0.58	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	35221	0.21
chr17_26372112_26372274	0.58	NLK	nemo-like kinase	2328	0.24
chr12_28120085_28120268	0.58	PTHLH	parathyroid hormone-like hormone	2251	0.33
chr2_202904203_202904368	0.58	FZD7	frizzled family receptor 7	4975	0.19
chr4_108745368_108745519	0.57	SGMS2	sphingomyelin synthase 2	276	0.93
chr2_38295840_38295991	0.57	RMDN2-AS1	RMDN2 antisense RNA 1	1731	0.34
chr10_104102183_104102477	0.57	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	51537	0.08
chr4_77610213_77610516	0.57	AC107072.2		51588	0.12
chr17_45698884_45699286	0.57	NPEPPS	aminopeptidase puromycin sensitive	3369	0.19
chr6_134492010_134492298	0.56	SGK1	serum/glucocorticoid regulated kinase 1	3848	0.24
chr2_109210392_109210708	0.56	LIMS1	LIM and senescent cell antigen-like domains 1	5628	0.26
chr15_60667686_60667929	0.56	ANXA2	annexin A2	1103	0.63
chr7_28726429_28726958	0.56	CREB5	cAMP responsive element binding protein 5	1095	0.68
chr7_95107815_95108198	0.56	ASB4	ankyrin repeat and SOCS box containing 4	7207	0.2
chr7_102553717_102554092	0.56	LRRC17	leucine rich repeat containing 17	452	0.83
chr10_33622034_33622426	0.56	NRP1	neuropilin 1	1080	0.63
chr15_96884556_96884898	0.56	ENSG00000222651	.	8237	0.16
chr5_96180027_96180310	0.56	CTD-2260A17.2	Uncharacterized protein	29147	0.12
chr4_112244997_112245242	0.56	ENSG00000200963	.	7449	0.34
chr15_59663421_59663716	0.56	FAM81A	family with sequence similarity 81, member A	1324	0.28
chr18_77225876_77226142	0.55	AC018445.1	Uncharacterized protein	50048	0.15
chr9_40632604_40633916	0.55	SPATA31A3	SPATA31 subfamily A, member 3	67031	0.14
chr5_174178214_174178699	0.55	ENSG00000266890	.	281	0.94
chr4_57975072_57975270	0.55	IGFBP7-AS1	IGFBP7 antisense RNA 1	757	0.52
chr9_96902091_96902301	0.55	ENSG00000199165	.	36038	0.13
chr5_57751342_57751690	0.55	PLK2	polo-like kinase 2	4571	0.26
chr4_146729352_146729578	0.55	RP11-181K12.2		24805	0.2
chr9_96819103_96819334	0.55	PTPDC1	protein tyrosine phosphatase domain containing 1	26142	0.21
chr17_46970773_46971045	0.55	ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	234	0.87
chr22_29106398_29106549	0.55	CHEK2	checkpoint kinase 2	1446	0.37
chr8_142048186_142048475	0.55	PTK2	protein tyrosine kinase 2	36121	0.17
chr2_161522670_161522919	0.54	RBMS1	RNA binding motif, single stranded interacting protein 1	172489	0.03
chr16_27378896_27379134	0.54	IL4R	interleukin 4 receptor	15019	0.19
chr12_22059820_22060034	0.54	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	3985	0.3
chr7_82188634_82189045	0.54	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	115725	0.07
chr16_14279913_14280368	0.54	MKL2	MKL/myocardin-like 2	434	0.86
chr4_139011510_139011683	0.54	ENSG00000250033	.	1428	0.6
chr20_4953796_4953984	0.54	SLC23A2	solute carrier family 23 (ascorbic acid transporter), member 2	28255	0.16
chr11_75315135_75315603	0.54	CTD-2530H12.8		7054	0.14
chr5_72327202_72327380	0.54	ENSG00000200833	.	68609	0.09
chr15_48436377_48436744	0.54	MYEF2	myelin expression factor 2	4963	0.17
chr11_17096963_17097114	0.53	ENSG00000201403	.	377	0.59
chr10_129809540_129809846	0.53	PTPRE	protein tyrosine phosphatase, receptor type, E	13303	0.26
chr4_151500337_151500655	0.53	RP11-1336O20.2		255	0.93
chr5_3597777_3597928	0.53	IRX1	iroquois homeobox 1	1684	0.41
chr8_32085203_32085460	0.53	NRG1-IT2	NRG1 intronic transcript 2 (non-protein coding)	6887	0.22
chr6_144016553_144016704	0.53	PHACTR2	phosphatase and actin regulator 2	17423	0.25
chr11_46237993_46238166	0.53	CTD-2589M5.4		58019	0.1
chr5_127149430_127149726	0.53	CTC-548H10.2		149857	0.04
chr5_83680805_83681167	0.53	CTD-2269F5.1		311	0.56
chr2_58266503_58266768	0.53	VRK2	vaccinia related kinase 2	7094	0.27
chr5_88178054_88178448	0.53	MEF2C	myocyte enhancer factor 2C	713	0.52
chr12_24103066_24103383	0.53	SOX5	SRY (sex determining region Y)-box 5	587	0.86
chr3_174675589_174675952	0.53	NAALADL2	N-acetylated alpha-linked acidic dipeptidase-like 2	98700	0.09
chr9_104248314_104249564	0.52	TMEM246	transmembrane protein 246	460	0.79
chr4_79215331_79215502	0.52	FRAS1	Fraser syndrome 1	39016	0.21
chr4_182568542_182568740	0.52	ENSG00000251742	.	187620	0.03
chr2_230138192_230138530	0.52	PID1	phosphotyrosine interaction domain containing 1	2360	0.4
chr13_80912572_80913077	0.52	SPRY2	sprouty homolog 2 (Drosophila)	970	0.67
chr8_16689434_16690090	0.52	ENSG00000264092	.	31243	0.24
chr14_101867418_101867569	0.52	ENSG00000258498	.	159266	0.02
chr8_57086542_57086822	0.52	PLAG1	pleiomorphic adenoma gene 1	37156	0.12
chr20_52271481_52272252	0.52	ENSG00000238468	.	13431	0.22
chr6_38230060_38230313	0.52	ENSG00000200706	.	55136	0.16
chr4_41215270_41215769	0.52	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	956	0.59
chr1_196577911_196578299	0.52	KCNT2	potassium channel, subfamily T, member 2	250	0.94
chrX_114828631_114828846	0.52	PLS3	plastin 3	873	0.64
chr1_57041430_57041821	0.51	PPAP2B	phosphatidic acid phosphatase type 2B	3616	0.34
chr12_16500369_16500557	0.51	MGST1	microsomal glutathione S-transferase 1	116	0.98
chr6_130690776_130691119	0.51	TMEM200A	transmembrane protein 200A	4068	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.5	1.5	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.4	1.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	0.8	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.7	GO:0030210	heparin biosynthetic process(GO:0030210)
0.2	0.9	GO:0060013	righting reflex(GO:0060013)
0.2	0.6	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.2	0.8	GO:0060437	lung growth(GO:0060437)
0.2	1.2	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2	0.5	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	0.5	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.2	0.2	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.2	1.0	GO:0008354	germ cell migration(GO:0008354)
0.2	0.6	GO:0048539	bone marrow development(GO:0048539)
0.2	0.2	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.4	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.4	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.4	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.4	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1	1.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.5	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.5	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.5	GO:0010107	potassium ion import(GO:0010107)
0.1	0.6	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	0.5	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.3	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.4	GO:0010667	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.4	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.6	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.7	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	2.8	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.1	0.4	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.4	GO:0061004	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.4	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.3	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.1	0.9	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.1	0.3	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1	0.3	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.4	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.1	0.3	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1	0.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.1	0.3	GO:0045112	integrin biosynthetic process(GO:0045112)
0.1	0.5	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.9	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.2	GO:0060900	optic cup morphogenesis involved in camera-type eye development(GO:0002072) embryonic camera-type eye formation(GO:0060900)
0.1	0.3	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.5	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.5	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.3	GO:0090399	replicative senescence(GO:0090399)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	1.8	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0060535	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.5	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.5	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.1	0.4	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.4	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	1.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.2	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.1	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.2	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.1	GO:0033088	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	2.0	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.2	GO:0007412	axon target recognition(GO:0007412)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0060297	regulation of sarcomere organization(GO:0060297)
0.1	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.1	0.2	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.1	0.4	GO:0002076	osteoblast development(GO:0002076)
0.1	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.1	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.1	0.2	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.1	0.2	GO:0031657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.5	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.1	0.3	GO:0016246	RNA interference(GO:0016246)
0.1	0.1	GO:0090081	regulation of Wnt signaling pathway involved in heart development(GO:0003307) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1	0.2	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.7	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.6	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.9	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.1	GO:0072010	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.1	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:1903170	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.0	2.2	GO:0034332	adherens junction organization(GO:0034332)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.0	0.0	GO:1903514	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.2	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.6	GO:0048538	thymus development(GO:0048538)
0.0	0.3	GO:1901863	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.4	GO:0007320	insemination(GO:0007320)
0.0	0.2	GO:0008347	glial cell migration(GO:0008347)
0.0	0.3	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.4	GO:0006949	syncytium formation(GO:0006949)
0.0	0.1	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.5	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	1.1	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.1	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0051140	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0035112	genitalia morphogenesis(GO:0035112) male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.9	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.4	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.5	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.0	GO:0032352	positive regulation of hormone metabolic process(GO:0032352) positive regulation of hormone biosynthetic process(GO:0046886)
0.0	0.4	GO:0046697	decidualization(GO:0046697)
0.0	0.1	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.4	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0	0.0	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0051584	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.2	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.2	GO:0072666	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.1	GO:0070977	organ maturation(GO:0048799) bone maturation(GO:0070977)
0.0	0.0	GO:0002246	wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.0	GO:1903670	regulation of cell migration involved in sprouting angiogenesis(GO:0090049) regulation of sprouting angiogenesis(GO:1903670)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.2	GO:0045109	intermediate filament organization(GO:0045109)
0.0	0.4	GO:0046068	cGMP metabolic process(GO:0046068)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.3	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.3	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.2	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.5	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.2	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.6	GO:0030318	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.2	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.0	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0032070	regulation of deoxyribonuclease activity(GO:0032070)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.1	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.2	GO:0043949	regulation of cAMP-mediated signaling(GO:0043949)
0.0	0.1	GO:0032310	regulation of icosanoid secretion(GO:0032303) positive regulation of icosanoid secretion(GO:0032305) regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308) prostaglandin secretion(GO:0032310)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.1	GO:0035929	steroid hormone secretion(GO:0035929)
0.0	0.0	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.0	GO:0055117	regulation of cardiac muscle contraction(GO:0055117)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0008589	regulation of smoothened signaling pathway(GO:0008589)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.1	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0006337	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.3	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.0	0.1	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.3	GO:1905037	autophagosome assembly(GO:0000045) autophagosome organization(GO:1905037)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.0	GO:0048263	determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0	0.0	GO:2000649	regulation of sodium:proton antiporter activity(GO:0032415) regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0	0.0	GO:0003283	atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.2	GO:0003016	respiratory system process(GO:0003016)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.0	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.0	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.1	GO:0016115	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0	0.3	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0006228	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	1.8	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:0033687	osteoblast proliferation(GO:0033687)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0061036	positive regulation of cartilage development(GO:0061036)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.0	GO:0042748	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.4	GO:0007043	cell-cell junction assembly(GO:0007043)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.0	0.0	GO:0034445	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:1904181	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.1	GO:0046622	positive regulation of organ growth(GO:0046622)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.0	GO:0090494	dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0	0.3	GO:0005980	glycogen catabolic process(GO:0005980)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0021535	cell migration in hindbrain(GO:0021535)
0.0	0.3	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.3	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0046471	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0060231	mesenchymal to epithelial transition(GO:0060231)
0.0	0.1	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0001756	somitogenesis(GO:0001756)
0.0	0.0	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0046856	phosphatidylinositol dephosphorylation(GO:0046856)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0	0.4	GO:0060070	canonical Wnt signaling pathway(GO:0060070)
0.0	0.4	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.0	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0090114	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.0	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.0	GO:0042640	anagen(GO:0042640)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.6	GO:0007623	circadian rhythm(GO:0007623)
0.0	0.0	GO:0032782	canalicular bile acid transport(GO:0015722) bile acid secretion(GO:0032782)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0042417	dopamine metabolic process(GO:0042417)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.2	GO:1901343	negative regulation of vasculature development(GO:1901343)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.0	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.0	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0034086	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.0	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0060079	excitatory postsynaptic potential(GO:0060079)
0.0	0.1	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.0	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0	0.0	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0051923	sulfation(GO:0051923)
0.0	0.0	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	0.5	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.5	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.0	GO:0005587	collagen type IV trimer(GO:0005587)
0.1	0.5	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.9	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.5	GO:0010369	chromocenter(GO:0010369)
0.1	0.7	GO:0016342	catenin complex(GO:0016342)
0.1	0.6	GO:0030673	axolemma(GO:0030673)
0.1	0.7	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.1	0.1	GO:0070852	cell body fiber(GO:0070852)
0.1	0.5	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.1	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.8	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0071437	invadopodium(GO:0071437)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.8	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0070938	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.9	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.3	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.6	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	2.2	GO:0030426	growth cone(GO:0030426)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.4	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.4	GO:0005884	actin filament(GO:0005884)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.4	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.3	GO:0042581	specific granule(GO:0042581)
0.0	1.4	GO:0005604	basement membrane(GO:0005604)
0.0	0.0	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	5.2	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.0	GO:0045178	basal part of cell(GO:0045178)
0.0	1.6	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.0	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.5	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0000145	exocyst(GO:0000145)
0.0	0.5	GO:0005902	microvillus(GO:0005902)
0.0	0.1	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.6	GO:0036064	ciliary basal body(GO:0036064)
0.0	1.5	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.4	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:1903561	extracellular organelle(GO:0043230) extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.9	GO:0043296	apical junction complex(GO:0043296)
0.0	0.0	GO:0033643	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.8	GO:0001726	ruffle(GO:0001726)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.3	GO:0031674	I band(GO:0031674)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.8	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.4	1.3	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	1.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	0.9	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.6	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	1.0	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.6	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	0.6	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	1.7	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2	0.5	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.5	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.2	0.6	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	2.4	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.5	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.6	GO:0042805	actinin binding(GO:0042805)
0.1	0.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	1.0	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.5	GO:0005534	galactose binding(GO:0005534)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.4	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1	0.4	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.6	GO:0017166	vinculin binding(GO:0017166)
0.1	0.5	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.1	0.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.5	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.4	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.4	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	1.0	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.3	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.7	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	1.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	0.3	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.1	0.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	0.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	1.7	GO:0005518	collagen binding(GO:0005518)
0.1	1.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.0	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.4	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.5	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.7	GO:0045296	cadherin binding(GO:0045296)
0.0	0.2	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.1	GO:0032052	bile acid binding(GO:0032052)
0.0	0.8	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.4	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0019958	C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.3	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.5	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.3	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	1.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.3	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.4	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.5	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.5	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.5	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	2.5	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.3	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.4	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.3	GO:0030145	manganese ion binding(GO:0030145)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.0	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	1.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0035252	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.1	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.3	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.0	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.0	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.7	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.5	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.0	GO:0031420	alkali metal ion binding(GO:0031420)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.2	GO:0005184	neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.1	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	2.8	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	1.0	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	1.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.8	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID CDC42 PATHWAY	CDC42 signaling events
0.0	1.1	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.0	SIG CHEMOTAXIS	Genes related to chemotaxis
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.5	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.7	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	3.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.3	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.5	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	2.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	ST GA13 PATHWAY	G alpha 13 Pathway
0.0	3.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.0	0.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	2.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.3	PID BMP PATHWAY	BMP receptor signaling
0.0	0.6	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.1	PID FGF PATHWAY	FGF signaling pathway
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID INSULIN PATHWAY	Insulin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	0.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.2	4.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	2.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	1.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	2.1	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.1	0.7	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	0.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.6	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.8	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	1.0	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	1.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.0	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.4	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.8	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME G1 S TRANSITION	Genes involved in G1/S Transition
0.0	1.4	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.6	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.7	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.5	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.3	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.6	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
0.0	0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	1.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.3	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.2	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Results for HOXB4_LHX9

Z-value: 1.21

Motif logo

Transcription factors associated with HOXB4_LHX9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXB4_LHX9 motif across conditions

Conditions sorted by the z-value of the HOXB4_LHX9 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB4_LHX9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: