Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HOXB5

Z-value: 0.76

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Transcription factors associated with HOXB5

Gene Symbol Gene ID Gene Info
HOXB5
ENSG00000120075.5 HOXB5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HOXB5chr17_46672091_466722428430.2835850.215.9e-01Click!
HOXB5chr17_46671860_466720116120.4196930.186.4e-01Click!
HOXB5chr17_46671414_466717662670.750635-0.059.1e-01Click!
HOXB5chr17_46670468_466711255270.463731-0.029.7e-01Click!

Activity of the HOXB5 motif across conditions

Conditions sorted by the z-value of the HOXB5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_150536014_150536165 0.41 ANXA6
 annexin A6
 1219
 0.5
chr19_17958305_17958511 0.36 JAK3
 Janus kinase 3
 418
 0.74
chr15_93276931_93277107 0.35 CTD-2313J17.5
47703
 0.14
chr10_22541853_22542149 0.35 EBLN1
 endogenous Bornavirus-like nucleoprotein 1
 43051
 0.13
chr1_225655628_225655947 0.32 RP11-496N12.6
2742
 0.3
chr1_88150357_88150552 0.31 ENSG00000199318
 .
 231398
 0.02
chr5_14441548_14441780 0.30 TRIO
 trio Rho guanine nucleotide exchange factor
 46893
 0.19
chrX_19817156_19817441 0.30 SH3KBP1
 SH3-domain kinase binding protein 1
 571
 0.85
chr15_89349083_89349246 0.29 ACAN
 aggrecan
 2174
 0.38
chr7_39170524_39170675 0.28 POU6F2
 POU class 6 homeobox 2
 45138
 0.18
chr1_228075022_228075233 0.28 ENSG00000264483
 .
 54257
 0.1
chr19_14143598_14143749 0.28 IL27RA
 interleukin 27 receptor, alpha
 1113
 0.26
chrX_57618068_57618312 0.26 ZXDB
 zinc finger, X-linked, duplicated B
 79
 0.99
chr20_45333994_45334145 0.26 SLC2A10
 solute carrier family 2 (facilitated glucose transporter), member 10
 4057
 0.22
chr10_61667583_61667734 0.25 CCDC6
 coiled-coil domain containing 6
 1244
 0.57
chr11_17671771_17671922 0.24 RP11-358H18.2
46641
 0.13
chr12_12602626_12602777 0.24 DUSP16
 dual specificity phosphatase 16
 71358
 0.09
chr3_115503593_115504040 0.24 ENSG00000243359
 .
 52899
 0.17
chr11_128370521_128370777 0.24 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 4640
 0.28
chr15_65903705_65903940 0.24 SLC24A1
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
 79
 0.66
chr5_121836809_121836973 0.23 CTC-210G5.1
22109
 0.24
chr11_113929660_113929818 0.23 ZBTB16
 zinc finger and BTB domain containing 16
 576
 0.79
chr12_88812261_88812515 0.23 ENSG00000199245
 .
 11831
 0.3
chr13_58205325_58205914 0.22 PCDH17
 protocadherin 17
 1036
 0.71
chr20_1637966_1638117 0.22 SIRPG
 signal-regulatory protein gamma
 319
 0.86
chr1_46632976_46633201 0.22 TSPAN1
 tetraspanin 1
 7671
 0.13
chr1_150124988_150125267 0.22 PLEKHO1
 pleckstrin homology domain containing, family O member 1
 2957
 0.21
chr5_118309425_118309661 0.21 DTWD2
 DTW domain containing 2
 14372
 0.2
chr1_59522819_59522970 0.21 FGGY
 FGGY carbohydrate kinase domain containing
 239416
 0.02
chr12_88811798_88812120 0.21 ENSG00000199245
 .
 12260
 0.3
chr9_36191581_36192111 0.21 CLTA
 clathrin, light chain A
 886
 0.58
chr1_157963513_157964097 0.21 KIRREL
 kin of IRRE like (Drosophila)
 370
 0.89
chr1_226863033_226863244 0.21 ITPKB-IT1
 ITPKB intronic transcript 1 (non-protein coding)
 370
 0.88
chrX_1653880_1654070 0.21 P2RY8
 purinergic receptor P2Y, G-protein coupled, 8
 2025
 0.36
chrY_1603880_1604065 0.21 NA
 NA
 > 106
 NA
chr2_74758029_74758308 0.21 HTRA2
 HtrA serine peptidase 2
 995
 0.23
chr12_14518062_14518320 0.21 ATF7IP
 activating transcription factor 7 interacting protein
 425
 0.88
chr1_243416937_243417168 0.20 CEP170
 centrosomal protein 170kDa
 430
 0.81
chr7_102036309_102036664 0.20 PRKRIP1
 PRKR interacting protein 1 (IL11 inducible)
 324
 0.8
chrX_39953289_39953491 0.20 BCOR
 BCL6 corepressor
 3266
 0.39
chr2_198160747_198160898 0.19 ANKRD44-IT1
 ANKRD44 intronic transcript 1 (non-protein coding)
 6421
 0.18
chr14_51027599_51027854 0.19 MAP4K5
 mitogen-activated protein kinase kinase kinase kinase 5
 118
 0.91
chrX_20327856_20328007 0.19 RPS6KA3
 ribosomal protein S6 kinase, 90kDa, polypeptide 3
 42408
 0.18
chr10_97415335_97415893 0.19 ALDH18A1
 aldehyde dehydrogenase 18 family, member A1
 849
 0.66
chr3_128493983_128494134 0.19 ENSG00000244232
 .
 9932
 0.18
chr4_68411509_68411863 0.19 CENPC
 centromere protein C
 362
 0.89
chr1_26644827_26645344 0.18 UBXN11
 UBX domain protein 11
 231
 0.76
chrX_152600602_152600753 0.18 ZNF275
 zinc finger protein 275
 1064
 0.49
chr9_45781764_45781915 0.18 ENSG00000238930
 .
 26489
 0.19
chr6_110500956_110501177 0.18 WASF1
 WAS protein family, member 1
 60
 0.78
chr5_175621026_175621202 0.18 SIMC1
 SUMO-interacting motifs containing 1
 44251
 0.14
chrX_55545389_55545540 0.18 USP51
 ubiquitin specific peptidase 51
 29829
 0.17
chr12_7014349_7014709 0.17 LRRC23
 leucine rich repeat containing 23
 269
 0.76
chr5_98126794_98126945 0.17 RGMB
 repulsive guidance molecule family member b
 17530
 0.21
chr18_60825225_60825488 0.17 RP11-299P2.1
6803
 0.25
chr7_50344203_50344943 0.17 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 195
 0.97
chr5_139031248_139031399 0.17 CXXC5
 CXXC finger protein 5
 749
 0.7
chr4_175056009_175056160 0.16 FBXO8
 F-box protein 8
 148730
 0.04
chr5_53765584_53765762 0.16 HSPB3
 heat shock 27kDa protein 3
 14228
 0.25
chr1_200639269_200639714 0.16 DDX59
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
 394
 0.89
chr8_122583317_122583658 0.16 ENSG00000263525
 .
 28252
 0.22
chr5_38445912_38446355 0.16 EGFLAM
 EGF-like, fibronectin type III and laminin G domains
 435
 0.81
chr11_19798727_19799172 0.16 NAV2
 neuron navigator 2
 64
 0.98
chr9_67737610_67737761 0.16 ENSG00000199432
 .
 26837
 0.15
chr1_212112149_212112479 0.16 ENSG00000212187
 .
 86589
 0.07
chr9_4661797_4662588 0.15 PPAPDC2
 phosphatidic acid phosphatase type 2 domain containing 2
 106
 0.96
chr9_46168095_46168246 0.15 ENSG00000238413
 .
 26495
 0.23
chr4_149363777_149364242 0.15 NR3C2
 nuclear receptor subfamily 3, group C, member 2
 337
 0.94
chr22_30641304_30641455 0.15 RP1-102K2.8
605
 0.52
chr1_153965101_153965403 0.15 RPS27
 ribosomal protein S27
 2014
 0.15
chr9_97021933_97022185 0.15 ZNF169
 zinc finger protein 169
 449
 0.8
chr3_164914749_164914991 0.15 SLITRK3
 SLIT and NTRK-like family, member 3
 27
 0.99
chr22_30822061_30822534 0.15 MTFP1
 mitochondrial fission process 1
 492
 0.57
chr8_82193202_82194095 0.15 RP11-363E6.3
33
 0.92
chr9_45047006_45047157 0.15 ENSG00000238749
 .
 27178
 0.23
chr4_3304601_3305007 0.15 RGS12
 regulator of G-protein signaling 12
 5958
 0.26
chr19_24216997_24217256 0.14 ZNF254
 zinc finger protein 254
 850
 0.66
chr3_129205530_129205703 0.14 IFT122
 intraflagellar transport 122 homolog (Chlamydomonas)
 1418
 0.36
chr16_56709683_56709834 0.14 MT1H
 metallothionein 1H
 6006
 0.08
chr1_16276329_16276480 0.14 ZBTB17
 zinc finger and BTB domain containing 17
 5481
 0.16
chr13_48795647_48795882 0.14 ITM2B
 integral membrane protein 2B
 11530
 0.26
chr9_46336000_46336151 0.14 ENSG00000239090
 .
 26530
 0.17
chr10_29607372_29607594 0.14 LYZL1
 lysozyme-like 1
 29493
 0.23
chr12_6771613_6772265 0.14 ING4
 inhibitor of growth family, member 4
 310
 0.57
chr14_64009252_64009486 0.14 PPP2R5E
 protein phosphatase 2, regulatory subunit B', epsilon isoform
 647
 0.51
chr7_100181255_100181941 0.14 FBXO24
 F-box protein 24
 7
 0.93
chr14_22314825_22314976 0.14 ENSG00000222776
 .
 66115
 0.13
chr6_95345075_95345226 0.14 MANEA-AS1
 MANEA antisense RNA 1 (head to head)
 680176
 0.0
chr1_228652543_228652819 0.14 ENSG00000266174
 .
 2906
 0.12
chr11_117102027_117102760 0.14 PCSK7
 proprotein convertase subtilisin/kexin type 7
 191
 0.87
chr1_57039327_57039478 0.14 PPAP2B
 phosphatidic acid phosphatase type 2B
 5839
 0.3
chr2_8747464_8747615 0.14 AC011747.7
68357
 0.12
chr18_47339976_47340201 0.14 ACAA2
 acetyl-CoA acyltransferase 2
 219
 0.45
chr2_207938936_207939147 0.14 ENSG00000253008
 .
 35756
 0.16
chr2_65219193_65219344 0.14 ENSG00000252892
 .
 2612
 0.22
chr16_14014863_14015110 0.13 ERCC4
 excision repair cross-complementing rodent repair deficiency, complementation group 4
 972
 0.64
chr19_13262272_13262447 0.13 IER2
 immediate early response 2
 430
 0.63
chr6_3119416_3119591 0.13 BPHL
 biphenyl hydrolase-like (serine hydrolase)
 577
 0.68
chr1_145472532_145473065 0.13 ANKRD34A
 ankyrin repeat domain 34A
 2290
 0.15
chr2_98206021_98206285 0.13 ANKRD36B
 ankyrin repeat domain 36B
 31
 0.98
chr2_71175523_71175730 0.13 AC007040.7
56
 0.94
chr15_101667565_101667737 0.13 RP11-505E24.2
41380
 0.16
chr11_47430197_47430394 0.13 SLC39A13
 solute carrier family 39 (zinc transporter), member 13
 113
 0.75
chr6_4134531_4135049 0.13 RP3-400B16.4
867
 0.4
chr11_114271389_114271817 0.13 RBM7
 RNA binding motif protein 7
 207
 0.74
chr1_95389567_95389941 0.13 CNN3
 calponin 3, acidic
 1583
 0.36
chr20_19991582_19991882 0.13 NAA20
 N(alpha)-acetyltransferase 20, NatB catalytic subunit
 6028
 0.22
chr7_55433758_55433937 0.13 LANCL2
 LanC lantibiotic synthetase component C-like 2 (bacterial)
 706
 0.8
chr19_46498683_46499250 0.13 CCDC61
 coiled-coil domain containing 61
 220
 0.9
chr19_52592991_52593142 0.13 ZNF841
 zinc finger protein 841
 4292
 0.14
chrX_52964079_52964300 0.13 FAM156A
 family with sequence similarity 156, member A
 21340
 0.17
chr16_74640360_74640757 0.13 GLG1
 golgi glycoprotein 1
 434
 0.86
chr8_134511768_134511919 0.13 ST3GAL1
 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
 217
 0.97
chr5_114958288_114958558 0.13 TMED7-TICAM2
 TMED7-TICAM2 readthrough
 3288
 0.18
chr9_101848573_101848724 0.13 TGFBR1
 transforming growth factor, beta receptor 1
 17672
 0.22
chr1_85086822_85086974 0.13 C1orf180
 chromosome 1 open reading frame 180
 10533
 0.21
chr5_174906870_174907021 0.13 SFXN1
 sideroflexin 1
 1350
 0.48
chr2_10445528_10445697 0.12 HPCAL1
 hippocalcin-like 1
 1786
 0.33
chr3_149285300_149285451 0.12 WWTR1
 WW domain containing transcription regulator 1
 8664
 0.21
chr11_96073941_96074227 0.12 ENSG00000266192
 .
 518
 0.76
chr7_29899550_29899701 0.12 WIPF3
 WAS/WASL interacting protein family, member 3
 25284
 0.19
chrX_106872615_106872887 0.12 PRPS1
 phosphoribosyl pyrophosphate synthetase 1
 958
 0.65
chr7_100143879_100144474 0.12 AGFG2
 ArfGAP with FG repeats 2
 7294
 0.09
chr3_45430392_45430595 0.12 LARS2
 leucyl-tRNA synthetase 2, mitochondrial
 382
 0.91
chrX_70324263_70324497 0.12 CXorf65
 chromosome X open reading frame 65
 2075
 0.18
chr21_40983827_40983978 0.12 C21orf88
 chromosome 21 open reading frame 88
 466
 0.83
chr12_98990277_98990538 0.12 SLC25A3
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
 2904
 0.18
chr2_227476608_227476759 0.12 ENSG00000263363
 .
 46826
 0.19
chr8_101271300_101271587 0.12 RNF19A
 ring finger protein 19A, RBR E3 ubiquitin protein ligase
 44015
 0.13
chr5_157171107_157171579 0.12 LSM11
 LSM11, U7 small nuclear RNA associated
 640
 0.64
chr14_24641513_24641917 0.12 REC8
 REC8 meiotic recombination protein
 105
 0.89
chr2_192116601_192116752 0.12 MYO1B
 myosin IB
 5667
 0.29
chr18_54046096_54046251 0.12 TXNL1
 thioredoxin-like 1
 235549
 0.02
chr6_35267664_35267815 0.12 DEF6
 differentially expressed in FDCP 6 homolog (mouse)
 2110
 0.3
chr2_208757346_208757497 0.12 AC083900.1
22782
 0.19
chr20_25175950_25176201 0.12 ENTPD6
 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
 254
 0.92
chr1_156184119_156184270 0.12 PMF1-BGLAP
 PMF1-BGLAP readthrough
 1394
 0.21
chr11_2966476_2966712 0.12 PHLDA2
 pleckstrin homology-like domain, family A, member 2
 15909
 0.11
chr12_2943957_2944189 0.12 NRIP2
 nuclear receptor interacting protein 2
 117
 0.93
chr20_31069881_31070147 0.12 C20orf112
 chromosome 20 open reading frame 112
 1260
 0.46
chr1_53662768_53663349 0.12 CPT2
 carnitine palmitoyltransferase 2
 957
 0.4
chr6_34855495_34855727 0.11 TAF11
 TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
 208
 0.91
chr3_115342492_115342792 0.11 GAP43
 growth associated protein 43
 285
 0.94
chr12_68041813_68042274 0.11 DYRK2
 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
 75
 0.98
chr2_103034093_103034244 0.11 IL18RAP
 interleukin 18 receptor accessory protein
 981
 0.47
chr12_123714056_123714279 0.11 MPHOSPH9
 M-phase phosphoprotein 9
 826
 0.5
chr7_108060925_108061076 0.11 NRCAM
 neuronal cell adhesion molecule
 35765
 0.18
chr4_81018676_81018827 0.11 ANTXR2
 anthrax toxin receptor 2
 24125
 0.24
chr1_115809791_115809982 0.11 RP4-663N10.1
15769
 0.26
chrY_16636064_16636659 0.11 NLGN4Y
 neuroligin 4, Y-linked
 93
 0.99
chr15_29407577_29408042 0.11 APBA2
 amyloid beta (A4) precursor protein-binding, family A, member 2
 71282
 0.11
chrX_153978145_153979054 0.11 GAB3
 GRB2-associated binding protein 3
 733
 0.55
chr8_110551213_110551689 0.11 EBAG9
 estrogen receptor binding site associated, antigen, 9
 489
 0.82
chr13_24006549_24006700 0.11 SACS
 spastic ataxia of Charlevoix-Saguenay (sacsin)
 1217
 0.63
chr3_155053149_155053300 0.11 ENSG00000272096
 .
 102388
 0.07
chr19_17421267_17421418 0.11 ABHD8
 abhydrolase domain containing 8
 297
 0.69
chr7_24796179_24797014 0.11 DFNA5
 deafness, autosomal dominant 5
 498
 0.88
chr14_22957215_22957366 0.11 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 1119
 0.33
chr10_14051003_14051266 0.11 FRMD4A
 FERM domain containing 4A
 602
 0.78
chr17_76377369_76377979 0.11 PGS1
 phosphatidylglycerophosphate synthase 1
 2915
 0.19
chr7_27881960_27882111 0.11 TAX1BP1
 Tax1 (human T-cell leukemia virus type I) binding protein 1
 14615
 0.23
chr9_74516561_74516712 0.11 ENSG00000200922
 .
 830
 0.62
chr10_115235598_115235749 0.11 HABP2
 hyaluronan binding protein 2
 74923
 0.11
chr11_119235533_119235684 0.11 USP2
 ubiquitin specific peptidase 2
 691
 0.48
chr7_86842084_86842235 0.11 ENSG00000200397
 .
 5869
 0.19
chr8_22876157_22876423 0.11 RP11-875O11.1
558
 0.66
chr15_82337650_82337919 0.11 MEX3B
 mex-3 RNA binding family member B
 676
 0.58
chr11_43600318_43600534 0.11 ENSG00000199077
 .
 2518
 0.32
chr1_226252983_226253134 0.11 H3F3A
 H3 histone, family 3A
 1380
 0.39
chr12_26112779_26113361 0.11 RASSF8-AS1
 RASSF8 atnisense RNA 1
 372
 0.8
chr9_130638533_130638684 0.11 AK1
 adenylate kinase 1
 1322
 0.23
chr3_16006218_16006514 0.11 ENSG00000207815
 .
 91088
 0.08
chr2_127415770_127416175 0.11 GYPC
 glycophorin C (Gerbich blood group)
 2212
 0.42
chr10_102414163_102414356 0.11 PAX2
 paired box 2
 91209
 0.07
chr18_46474661_46474872 0.10 SMAD7
 SMAD family member 7
 109
 0.98
chr2_88124610_88124761 0.10 RGPD2
 RANBP2-like and GRIP domain containing 2
 601
 0.82
chr1_103574265_103574420 0.10 COL11A1
 collagen, type XI, alpha 1
 290
 0.95
chr7_28068761_28068999 0.10 JAZF1
 JAZF zinc finger 1
 8462
 0.28
chr1_202597824_202597975 0.10 SYT2
 synaptotagmin II
 14682
 0.19
chr8_146018268_146018550 0.10 RPL8
 ribosomal protein L8
 437
 0.71
chr7_93632108_93632388 0.10 BET1
 Bet1 golgi vesicular membrane trafficking protein
 1425
 0.47
chr15_101136944_101137114 0.10 LINS
 lines homolog (Drosophila)
 112
 0.95
chr11_19735220_19735722 0.10 NAV2
 neuron navigator 2
 328
 0.92
chr9_110512814_110512965 0.10 AL162389.1
 Uncharacterized protein
 27530
 0.19
chr9_113828644_113828795 0.10 LPAR1
 lysophosphatidic acid receptor 1
 27738
 0.2
chr4_24980238_24980389 0.10 CCDC149
 coiled-coil domain containing 149
 1457
 0.52
chr15_102286896_102287244 0.10 RP11-89K11.1
 Uncharacterized protein
 1157
 0.38
chr22_28838455_28839140 0.10 ENSG00000199797
 .
 139055
 0.04
chr12_97272342_97272601 0.10 NEDD1
 neural precursor cell expressed, developmentally down-regulated 1
 28530
 0.25
chr16_9051858_9052009 0.10 USP7
 ubiquitin specific peptidase 7 (herpes virus-associated)
 1696
 0.4
chr1_9477600_9477751 0.10 ENSG00000252956
 .
 20162
 0.21
chr2_131862982_131863218 0.10 PLEKHB2
 pleckstrin homology domain containing, family B (evectins) member 2
 174
 0.95
chr5_53815643_53816423 0.10 SNX18
 sorting nexin 18
 2440
 0.4
chr18_21598879_21599226 0.10 TTC39C
 tetratricopeptide repeat domain 39C
 2454
 0.25
chr10_74094555_74094706 0.10 DNAJB12
 DnaJ (Hsp40) homolog, subfamily B, member 12
 10089
 0.19
chr19_53757624_53758099 0.10 ZNF677
 zinc finger protein 677
 80
 0.94
chr9_139971485_139971648 0.10 UAP1L1
 UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
 387
 0.59
chr9_135547712_135547863 0.10 DDX31
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
 1999
 0.3
chr11_4658372_4658526 0.10 OR51D1
 olfactory receptor, family 51, subfamily D, member 1
 2496
 0.19
chr19_56676041_56676192 0.10 GALP
 galanin-like peptide
 11273
 0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HOXB5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.2 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.1 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0010587 miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0021894 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.5 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.1 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.0 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.0 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.0 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.1 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0044447 axoneme part(GO:0044447)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.2 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0070061 fructose binding(GO:0070061)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.0 GO:0004476 mannose-6-phosphate isomerase activity(GO:0004476)
0.0 0.1 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.0 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.0 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling