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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXB7

Z-value: 0.71

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Transcription factors associated with HOXB7

Gene Symbol	Gene ID	Gene Info
HOXB7 Ensembl NCBI GeneCards UniProt	ENSG00000260027.3	homeobox B7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_46689472_46689623	HOXB7	1168	0.200623	-0.51	1.6e-01	Click!
chr17_46689288_46689439	HOXB7	984	0.253496	-0.31	4.1e-01	Click!
chr17_46687171_46687469	HOXB7	1059	0.249359	-0.27	4.8e-01	Click!
chr17_46687737_46688442	HOXB7	290	0.742304	0.01	9.7e-01	Click!
chr17_46688443_46688779	HOXB7	232	0.797135	-0.01	9.9e-01	Click!

Activity of the HOXB7 motif across conditions

Conditions sorted by the z-value of the HOXB7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr21_15917471_15917848	0.60	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1	1003	0.63
chr1_9713633_9713784	0.55	C1orf200	chromosome 1 open reading frame 200	936	0.49
chr13_46755018_46755169	0.48	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1366	0.39
chr12_25207113_25207806	0.47	LRMP	lymphoid-restricted membrane protein	1785	0.37
chr5_57787350_57787738	0.46	GAPT	GRB2-binding adaptor protein, transmembrane	280	0.92
chr19_48752565_48752795	0.46	CARD8	caspase recruitment domain family, member 8	245	0.88
chr7_106507057_106507208	0.45	PIK3CG	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma	1208	0.59
chr2_175461579_175461860	0.44	WIPF1	WAS/WASL interacting protein family, member 1	774	0.64
chr8_133771865_133772108	0.44	TMEM71	transmembrane protein 71	808	0.63
chr13_31309966_31310295	0.43	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	485	0.88
chr2_161995820_161996335	0.43	TANK	TRAF family member-associated NFKB activator	2611	0.33
chr6_6396318_6396469	0.42	F13A1	coagulation factor XIII, A1 polypeptide	75147	0.11
chr14_90084669_90085459	0.42	FOXN3	forkhead box N3	410	0.78
chr4_100738015_100738341	0.42	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	175	0.97
chr16_11677800_11677980	0.40	LITAF	lipopolysaccharide-induced TNF factor	2339	0.3
chrX_13103844_13104411	0.39	FAM9C	family with sequence similarity 9, member C	41326	0.19
chr8_124049779_124050367	0.38	TBC1D31	TBC1 domain family, member 31	4135	0.17
chr6_7698975_7699328	0.38	BMP6	bone morphogenetic protein 6	27879	0.23
chr9_127520429_127520580	0.37	RP11-175D17.3		11898	0.14
chr4_68424446_68424654	0.37	STAP1	signal transducing adaptor family member 1	104	0.97
chr12_104854519_104854691	0.37	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	3826	0.33
chr8_82022711_82022967	0.36	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	1464	0.56
chr7_139529936_139530130	0.36	TBXAS1	thromboxane A synthase 1 (platelet)	923	0.68
chr15_52121866_52123371	0.36	TMOD3	tropomodulin 3 (ubiquitous)	791	0.61
chr8_67575803_67576925	0.36	VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	3088	0.17
chr22_21273701_21274522	0.36	CRKL	v-crk avian sarcoma virus CT10 oncogene homolog-like	2397	0.18
chr1_184127977_184128128	0.35	ENSG00000199840	.	12905	0.26
chr1_67396775_67397508	0.34	MIER1	mesoderm induction early response 1, transcriptional regulator	1215	0.49
chr11_118111192_118111343	0.34	MPZL3	myelin protein zero-like 3	11795	0.13
chr3_151963279_151963566	0.34	MBNL1	muscleblind-like splicing regulator 1	22407	0.21
chr13_46753488_46753737	0.34	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	2847	0.22
chr13_41555714_41555943	0.34	ELF1	E74-like factor 1 (ets domain transcription factor)	590	0.77
chr9_71321312_71321473	0.33	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta	776	0.74
chr12_51716594_51716774	0.33	BIN2	bridging integrator 2	1215	0.42
chr19_48759351_48759594	0.33	CARD8	caspase recruitment domain family, member 8	269	0.69
chr2_197025134_197025564	0.32	STK17B	serine/threonine kinase 17b	3978	0.23
chr13_99911056_99911338	0.32	GPR18	G protein-coupled receptor 18	515	0.8
chr5_169720489_169720914	0.31	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	4530	0.26
chr10_126406911_126407062	0.31	FAM53B-AS1	FAM53B antisense RNA 1	14233	0.17
chr11_104914640_104914826	0.31	CARD16	caspase recruitment domain family, member 16	1301	0.41
chr13_46752366_46752713	0.31	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	3920	0.19
chr19_42056193_42056486	0.31	CEACAM21	carcinoembryonic antigen-related cell adhesion molecule 21	453	0.8
chr5_57787974_57788125	0.31	GAPT	GRB2-binding adaptor protein, transmembrane	785	0.66
chr7_45068352_45068655	0.31	CCM2	cerebral cavernous malformation 2	1232	0.4
chr20_24971841_24971992	0.30	APMAP	adipocyte plasma membrane associated protein	1362	0.42
chr7_37723646_37724017	0.30	GPR141	G protein-coupled receptor 141	356	0.51
chr3_48309303_48309454	0.30	ENSG00000199476	.	20699	0.1
chr17_8770489_8770662	0.30	PIK3R6	phosphoinositide-3-kinase, regulatory subunit 6	419	0.85
chr20_54987227_54988129	0.30	CASS4	Cas scaffolding protein family member 4	361	0.82
chr19_52692676_52692917	0.30	PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	496	0.68
chr7_15277197_15277348	0.30	AGMO	alkylglycerol monooxygenase	128540	0.06
chr16_50874988_50875494	0.29	ENSG00000199771	.	28245	0.15
chr11_102192518_102192994	0.29	BIRC3	baculoviral IAP repeat containing 3	3196	0.22
chr4_36244695_36244948	0.29	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	740	0.5
chr11_104893749_104893900	0.29	CASP5	caspase 5, apoptosis-related cysteine peptidase	39	0.97
chr13_41555230_41555381	0.29	ELF1	E74-like factor 1 (ets domain transcription factor)	1113	0.53
chr15_80262648_80263745	0.28	BCL2A1	BCL2-related protein A1	315	0.89
chr13_41589998_41590808	0.28	ELF1	E74-like factor 1 (ets domain transcription factor)	3047	0.26
chr19_17861983_17862176	0.28	FCHO1	FCH domain only 1	207	0.91
chr2_43242041_43242199	0.28	ENSG00000207087	.	76512	0.11
chrY_1604612_1604993	0.28	NA	NA	> 10⁶	NA
chr6_74160199_74160458	0.28	MB21D1	Mab-21 domain containing 1	1654	0.21
chr1_8456613_8456764	0.28	RERE	arginine-glutamic acid dipeptide (RE) repeats	27038	0.16
chr8_78851968_78852119	0.28	ENSG00000252935	.	458814	0.01
chr13_46755198_46755455	0.28	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	1133	0.45
chr18_43780070_43780221	0.28	C18orf25	chromosome 18 open reading frame 25	26145	0.19
chr2_208395832_208396657	0.28	CREB1	cAMP responsive element binding protein 1	1416	0.37
chr11_33912422_33912614	0.28	LMO2	LIM domain only 2 (rhombotin-like 1)	1318	0.47
chr16_85096756_85096907	0.28	KIAA0513	KIAA0513	13	0.98
chr1_198612293_198612464	0.28	PTPRC	protein tyrosine phosphatase, receptor type, C	4086	0.29
chr17_29645805_29646348	0.28	CTD-2370N5.3		227	0.88
chr2_24114630_24115019	0.27	ATAD2B	ATPase family, AAA domain containing 2B	24067	0.18
chr11_104914891_104915295	0.27	CARD16	caspase recruitment domain family, member 16	941	0.54
chr4_153600093_153601094	0.27	TMEM154	transmembrane protein 154	571	0.78
chr1_101360811_101360994	0.27	RP4-549L20.3		418	0.45
chrX_1654663_1654996	0.27	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	1171	0.53
chr3_112693329_112693480	0.27	CD200R1	CD200 receptor 1	355	0.85
chrX_22014882_22015033	0.27	PHEX	phosphate regulating endopeptidase homolog, X-linked	35602	0.16
chr22_40858929_40859404	0.27	MKL1	megakaryoblastic leukemia (translocation) 1	256	0.92
chr11_113945554_113945705	0.27	ENSG00000221112	.	12022	0.21
chr2_158291882_158292250	0.27	CYTIP	cytohesin 1 interacting protein	3860	0.26
chr14_70110947_70111098	0.27	KIAA0247	KIAA0247	32709	0.18
chr11_104904746_104905919	0.27	CASP1	caspase 1, apoptosis-related cysteine peptidase	508	0.77
chr9_3398052_3398553	0.26	RFX3	regulatory factor X, 3 (influences HLA class II expression)	2706	0.4
chr17_78755045_78755196	0.26	RP11-28G8.1		24312	0.21
chr1_186344914_186345943	0.26	C1orf27	chromosome 1 open reading frame 27	427	0.56
chr19_17862364_17862733	0.26	FCHO1	FCH domain only 1	203	0.91
chr5_96152602_96152931	0.26	ERAP1	endoplasmic reticulum aminopeptidase 1	8963	0.15
chr2_158299843_158300108	0.26	CYTIP	cytohesin 1 interacting protein	679	0.68
chr16_57577463_57577729	0.26	GPR114	G protein-coupled receptor 114	995	0.47
chr18_29524153_29524304	0.26	TRAPPC8	trafficking protein particle complex 8	1159	0.37
chr2_152494266_152494505	0.26	NEB	nebulin	54252	0.17
chr4_84161976_84162127	0.26	COQ2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	43867	0.16
chr11_128436857_128437008	0.25	ETS1	v-ets avian erythroblastosis virus E26 oncogene homolog 1	20521	0.21
chr10_105670292_105670878	0.25	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1	6842	0.18
chr12_51637020_51637171	0.25	DAZAP2	DAZ associated protein 2	4016	0.16
chrX_78407653_78407829	0.25	GPR174	G protein-coupled receptor 174	18728	0.29
chr3_56789114_56789483	0.25	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	20297	0.25
chr4_40209794_40209945	0.25	RHOH	ras homolog family member H	7905	0.22
chr4_38805465_38805725	0.25	TLR1	toll-like receptor 1	402	0.82
chr5_39275110_39275284	0.25	FYB	FYN binding protein	567	0.84
chr8_22961002_22961301	0.25	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	717	0.58
chr22_26968957_26969108	0.25	TPST2	tyrosylprotein sulfotransferase 2	7340	0.16
chr3_71834842_71834993	0.25	PROK2	prokineticin 2	560	0.77
chr1_112016807_112017159	0.25	C1orf162	chromosome 1 open reading frame 162	492	0.65
chr12_50914127_50914398	0.25	DIP2B	DIP2 disco-interacting protein 2 homolog B (Drosophila)	15372	0.22
chr2_60783649_60784435	0.25	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	3340	0.31
chr7_107516405_107516556	0.25	DLD	dihydrolipoamide dehydrogenase	14935	0.2
chr2_198121070_198121286	0.25	ANKRD44-IT1	ANKRD44 intronic transcript 1 (non-protein coding)	46065	0.12
chr10_73516376_73516547	0.24	C10orf54	chromosome 10 open reading frame 54	926	0.59
chrX_135862395_135862685	0.24	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	1707	0.34
chr12_69724195_69724437	0.24	LYZ	lysozyme	17805	0.16
chr6_139352039_139352190	0.24	ABRACL	ABRA C-terminal like	2135	0.38
chr10_81055079_81055263	0.24	ZMIZ1	zinc finger, MIZ-type containing 1	10804	0.24
chr2_162101279_162101855	0.24	AC009299.2		6106	0.21
chr10_77054575_77055573	0.24	COMTD1	catechol-O-methyltransferase domain containing 1	59305	0.11
chr17_19881734_19881885	0.24	AKAP10	A kinase (PRKA) anchor protein 10	659	0.69
chr7_37714024_37714249	0.24	GPR141	G protein-coupled receptor 141	9264	0.23
chr7_50345819_50346403	0.24	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1733	0.5
chr3_134262191_134262342	0.24	CEP63	centrosomal protein 63kDa	2732	0.31
chr17_8191755_8191938	0.23	RANGRF	RAN guanine nucleotide release factor	31	0.95
chr5_172264533_172264805	0.23	ERGIC1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	3255	0.24
chr22_40781146_40781297	0.23	RP5-1042K10.10		3000	0.21
chr1_226919008_226919177	0.23	ITPKB	inositol-trisphosphate 3-kinase B	6067	0.25
chr2_68594752_68594961	0.23	AC015969.3		2140	0.26
chr7_50348888_50349341	0.23	IKZF1	IKAROS family zinc finger 1 (Ikaros)	796	0.76
chr2_182173706_182173857	0.23	ENSG00000266705	.	3402	0.38
chr2_175462178_175462605	0.23	WIPF1	WAS/WASL interacting protein family, member 1	102	0.97
chr19_2562414_2562565	0.23	CTC-265F19.2		49371	0.09
chr1_9717913_9718080	0.23	C1orf200	chromosome 1 open reading frame 200	3352	0.21
chr3_15372748_15373059	0.23	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	1164	0.41
chr1_8487851_8488127	0.23	RP5-1115A15.1		2291	0.28
chr17_17661259_17661410	0.23	RAI1-AS1	RAI1 antisense RNA 1	12801	0.13
chr2_43448588_43448818	0.23	ZFP36L2	ZFP36 ring finger protein-like 2	5045	0.26
chr20_43599792_43600332	0.23	STK4	serine/threonine kinase 4	4895	0.16
chr13_75899167_75899318	0.22	TBC1D4	TBC1 domain family, member 4	16425	0.24
chr16_90169140_90169408	0.22	PRDM7	PR domain containing 7	26936	0.14
chr1_8455141_8455292	0.22	RERE	arginine-glutamic acid dipeptide (RE) repeats	28510	0.15
chr11_118134278_118134482	0.22	MPZL2	myelin protein zero-like 2	617	0.64
chr12_14519454_14519964	0.22	ATF7IP	activating transcription factor 7 interacting protein	549	0.82
chrX_78202733_78203002	0.22	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	1949	0.5
chr17_63025998_63026242	0.22	RP11-583F2.5		21907	0.15
chr2_223907796_223907991	0.22	KCNE4	potassium voltage-gated channel, Isk-related family, member 4	8639	0.28
chr3_69401946_69402170	0.22	FRMD4B	FERM domain containing 4B	790	0.78
chr9_102583033_102583358	0.22	NR4A3	nuclear receptor subfamily 4, group A, member 3	942	0.67
chr17_1133251_1133413	0.22	ABR	active BCR-related	1034	0.53
chr14_88472278_88472651	0.22	GPR65	G protein-coupled receptor 65	996	0.51
chr12_10281805_10282201	0.22	CLEC7A	C-type lectin domain family 7, member A	678	0.6
chr10_70850849_70851349	0.22	SRGN	serglycin	3225	0.25
chr10_126409764_126409915	0.22	FAM53B-AS1	FAM53B antisense RNA 1	17086	0.16
chr6_143140776_143141820	0.22	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	16886	0.26
chr3_57777559_57777710	0.22	SLMAP	sarcolemma associated protein	34349	0.18
chr21_36282308_36282468	0.22	RUNX1	runt-related transcription factor 1	20301	0.28
chr15_91955696_91955847	0.22	SV2B	synaptic vesicle glycoprotein 2B	186671	0.03
chr1_181474291_181474442	0.22	CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	21485	0.28
chr14_22898333_22898484	0.22	ENSG00000251002	.	3311	0.16
chr1_39284364_39284540	0.22	RRAGC	Ras-related GTP binding C	41043	0.12
chr5_169074909_169075202	0.22	DOCK2	dedicator of cytokinesis 2	10804	0.25
chr7_32530118_32530515	0.21	LSM5	LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)	286	0.93
chr4_110955377_110955528	0.21	ENSG00000207260	.	41971	0.17
chr7_36763519_36763817	0.21	AOAH	acyloxyacyl hydrolase (neutrophil)	386	0.9
chr10_5488617_5489358	0.21	NET1	neuroepithelial cell transforming 1	413	0.83
chr2_106412175_106412698	0.21	NCK2	NCK adaptor protein 2	20579	0.25
chr10_3514525_3515428	0.21	RP11-184A2.3		278283	0.01
chr1_153330986_153331137	0.21	S100A9	S100 calcium binding protein A9	731	0.51
chr8_41402017_41402168	0.21	RP11-360L9.7		196	0.92
chr3_148718458_148718609	0.21	GYG1	glycogenin 1	8375	0.2
chr11_65868544_65868961	0.21	PACS1	phosphofurin acidic cluster sorting protein 1	518	0.66
chr3_172237996_172238609	0.21	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	2963	0.33
chr6_114178016_114178613	0.21	MARCKS	myristoylated alanine-rich protein kinase C substrate	227	0.93
chr19_42127429_42127580	0.21	CEACAM4	carcinoembryonic antigen-related cell adhesion molecule 4	5938	0.16
chr7_5465601_5465997	0.21	TNRC18	trinucleotide repeat containing 18	754	0.57
chr10_27770228_27770379	0.21	RAB18	RAB18, member RAS oncogene family	22894	0.22
chr1_42230520_42230906	0.21	ENSG00000264896	.	5901	0.3
chr1_149969239_149969390	0.21	OTUD7B	OTU domain containing 7B	13310	0.14
chr4_73711574_73711725	0.21	ENSG00000252955	.	119246	0.06
chr13_28673907_28674274	0.21	FLT3	fms-related tyrosine kinase 3	617	0.74
chr2_198296439_198296590	0.21	SF3B1	splicing factor 3b, subunit 1, 155kDa	3237	0.18
chr11_82600826_82600977	0.21	C11orf82	chromosome 11 open reading frame 82	10116	0.19
chr17_67498077_67498704	0.21	MAP2K6	mitogen-activated protein kinase kinase 6	17	0.99
chr8_82044610_82044770	0.21	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	20387	0.26
chr2_197024297_197024448	0.21	STK17B	serine/threonine kinase 17b	3001	0.26
chr2_201987732_201987883	0.21	CFLAR	CASP8 and FADD-like apoptosis regulator	607	0.65
chr11_118110290_118110538	0.21	MPZL3	myelin protein zero-like 3	12648	0.13
chr9_134150778_134151758	0.21	FAM78A	family with sequence similarity 78, member A	666	0.69
chr3_197879582_197879733	0.21	AC073135.3		42580	0.13
chr12_50908341_50908492	0.21	DIP2B	DIP2 disco-interacting protein 2 homolog B (Drosophila)	9526	0.23
chr3_56949638_56949992	0.21	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	684	0.75
chr11_104838069_104839428	0.21	CASP4	caspase 4, apoptosis-related cysteine peptidase	1345	0.45
chr5_118606441_118606592	0.21	TNFAIP8	tumor necrosis factor, alpha-induced protein 8	2067	0.32
chr6_108144289_108144729	0.20	SCML4	sex comb on midleg-like 4 (Drosophila)	1007	0.66
chr5_134731392_134731690	0.20	H2AFY	H2A histone family, member Y	3360	0.2
chr2_61901363_61901639	0.20	ENSG00000206973	.	68750	0.11
chr21_45626968_45627290	0.20	AP001057.1		5956	0.14
chr1_185284734_185285261	0.20	IVNS1ABP	influenza virus NS1A binding protein	1464	0.44
chr9_117129321_117129472	0.20	AKNA	AT-hook transcription factor	9848	0.2
chr1_236043549_236043778	0.20	LYST	lysosomal trafficking regulator	3209	0.21
chrX_130962862_130963372	0.20	ENSG00000200587	.	109867	0.07
chr10_6110364_6110515	0.20	IL2RA	interleukin 2 receptor, alpha	6151	0.16
chrX_37691125_37691276	0.20	DYNLT3	dynein, light chain, Tctex-type 3	15461	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0002540	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.7	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.9	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1	0.4	GO:0030644	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.4	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.3	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.1	0.2	GO:0030210	heparin biosynthetic process(GO:0030210)
0.1	0.2	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.1	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.2	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.7	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1	0.1	GO:0032060	bleb assembly(GO:0032060)
0.1	0.2	GO:0032632	interleukin-3 production(GO:0032632)
0.1	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.6	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.1	0.2	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.5	GO:0015671	oxygen transport(GO:0015671)
0.1	0.2	GO:0002517	T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666)
0.1	0.2	GO:0048548	regulation of pinocytosis(GO:0048548)
0.1	0.2	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.1	0.9	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.1	0.5	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.1	0.2	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.2	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.2	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0000042	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.0	0.2	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0052166	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.3	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.3	GO:0060285	cilium-dependent cell motility(GO:0060285)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.3	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0002328	pro-B cell differentiation(GO:0002328)
0.0	0.2	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:1903020	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.0	GO:0046782	regulation of viral transcription(GO:0046782)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0	0.1	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0051570	regulation of histone H3-K9 methylation(GO:0051570)
0.0	0.2	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.2	GO:0032366	intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:1903224	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.3	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0046645	regulation of gamma-delta T cell differentiation(GO:0045586) positive regulation of gamma-delta T cell differentiation(GO:0045588) regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.7	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.2	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0010566	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.1	GO:0002507	tolerance induction(GO:0002507)
0.0	0.1	GO:0033345	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0	0.4	GO:0015939	pantothenate metabolic process(GO:0015939)
0.0	0.2	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.0	GO:0072191	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.1	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.1	GO:0006900	membrane budding(GO:0006900)
0.0	0.5	GO:0060334	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0034728	nucleosome organization(GO:0034728)
0.0	0.0	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.4	GO:0045646	regulation of erythrocyte differentiation(GO:0045646)
0.0	0.1	GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0007028	cytoplasm organization(GO:0007028)
0.0	0.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.8	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.1	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.1	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0	0.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0032490	detection of molecule of bacterial origin(GO:0032490)
0.0	0.2	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.6	GO:0002286	T cell activation involved in immune response(GO:0002286)
0.0	0.2	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.1	GO:0045767	obsolete regulation of anti-apoptosis(GO:0045767)
0.0	0.5	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:1901224	activation of NF-kappaB-inducing kinase activity(GO:0007250) NIK/NF-kappaB signaling(GO:0038061) regulation of NIK/NF-kappaB signaling(GO:1901222) positive regulation of NIK/NF-kappaB signaling(GO:1901224)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0032667	interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0	0.0	GO:0045357	interferon-beta biosynthetic process(GO:0045350) regulation of interferon-beta biosynthetic process(GO:0045357) positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0	0.1	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.0	0.1	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.7	GO:0006903	vesicle targeting(GO:0006903)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.0	GO:0046101	hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0020027	hemoglobin metabolic process(GO:0020027)
0.0	0.1	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.1	GO:0010587	miRNA metabolic process(GO:0010586) miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.3	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	1.1	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.1	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:0014742	positive regulation of cardiac muscle hypertrophy(GO:0010613) positive regulation of muscle hypertrophy(GO:0014742)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.4	GO:0007032	endosome organization(GO:0007032)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.4	GO:0051225	spindle assembly(GO:0051225)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	0.1	GO:0071025	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.3	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.0	GO:0016075	rRNA catabolic process(GO:0016075)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.0	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.2	GO:0042992	negative regulation of transcription factor import into nucleus(GO:0042992)
0.0	0.2	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0018202	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.3	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0043631	RNA polyadenylation(GO:0043631)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.0	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.3	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.2	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0072698	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.2	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0017004	cytochrome complex assembly(GO:0017004)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.0	GO:0071421	manganese ion transmembrane transport(GO:0071421)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0050702	interleukin-1 beta secretion(GO:0050702)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0019322	pentose biosynthetic process(GO:0019322)
0.0	0.0	GO:0010898	regulation of triglyceride catabolic process(GO:0010896) positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0001832	blastocyst growth(GO:0001832)
0.0	0.1	GO:0043388	positive regulation of DNA binding(GO:0043388)
0.0	0.0	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0	0.1	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.1	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0	0.0	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0042448	progesterone metabolic process(GO:0042448)
0.0	0.0	GO:0051383	kinetochore organization(GO:0051383)
0.0	0.0	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.1	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.7	GO:0031124	mRNA 3'-end processing(GO:0031124)
0.0	0.0	GO:0060251	regulation of glial cell proliferation(GO:0060251)
0.0	0.2	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.2	GO:0032092	positive regulation of protein binding(GO:0032092)
0.0	0.1	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.0	0.0	GO:0090559	regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0	0.1	GO:0046500	S-adenosylmethionine metabolic process(GO:0046500)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.3	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.0	GO:0070897	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.5	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.0	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0034626	fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.0	0.1	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.0	GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production(GO:0032725)
0.0	0.0	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.0	GO:0085020	protein K27-linked ubiquitination(GO:0044314) protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0021508	floor plate formation(GO:0021508)
0.0	0.0	GO:0014805	smooth muscle adaptation(GO:0014805)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.0	GO:0032226	positive regulation of synaptic transmission, dopaminergic(GO:0032226)
0.0	0.1	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.0	GO:0002320	lymphoid progenitor cell differentiation(GO:0002320)
0.0	0.1	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147) pyrimidine nucleoside triphosphate biosynthetic process(GO:0009148)
0.0	0.0	GO:0046132	pyrimidine ribonucleotide metabolic process(GO:0009218) pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.0	GO:0042640	anagen(GO:0042640)
0.0	0.1	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.0	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0000060	protein import into nucleus, translocation(GO:0000060)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0045056	transcytosis(GO:0045056)
0.0	0.4	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.8	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0	0.0	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	1.6	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
0.0	0.1	GO:1901998	antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.0	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.5	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.3	GO:0006626	protein targeting to mitochondrion(GO:0006626) establishment of protein localization to mitochondrion(GO:0072655)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0002639	positive regulation of immunoglobulin production(GO:0002639)
0.0	0.0	GO:0006998	nuclear envelope organization(GO:0006998)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:1904936	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.2	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.3	GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0	0.0	GO:0003170	heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0	1.3	GO:0097190	apoptotic signaling pathway(GO:0097190)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.2	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.0	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.0	GO:0032782	bile acid secretion(GO:0032782)
0.0	0.0	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.0	GO:0010575	positive regulation of vascular endothelial growth factor production(GO:0010575)
0.0	1.3	GO:0006333	chromatin assembly or disassembly(GO:0006333)
0.0	0.0	GO:0016574	histone ubiquitination(GO:0016574)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.0	GO:0042346	positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.0	0.0	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0003084	positive regulation of systemic arterial blood pressure(GO:0003084)
0.0	0.0	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0010922	positive regulation of phosphatase activity(GO:0010922)
0.0	0.0	GO:0044256	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.0	GO:0046015	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0	0.4	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.4	GO:0006446	regulation of translational initiation(GO:0006446)
0.0	0.1	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:0048617	foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.1	0.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0042629	mast cell granule(GO:0042629)
0.1	0.9	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0005826	actomyosin contractile ring(GO:0005826)
0.0	0.2	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0000805	X chromosome(GO:0000805)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.2	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.2	GO:0070822	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.4	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.5	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.2	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.3	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.3	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.2	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	2.0	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	1.0	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.3	GO:1903293	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.0	0.7	GO:0000790	nuclear chromatin(GO:0000790)
0.0	0.1	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.4	GO:0005626	obsolete insoluble fraction(GO:0005626)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.0	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.3	GO:0030667	secretory granule membrane(GO:0030667)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0001772	immunological synapse(GO:0001772)
0.0	0.3	GO:0015030	Cajal body(GO:0015030)
0.0	0.5	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.0	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.6	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	0.1	GO:0042588	zymogen granule(GO:0042588)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.0	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0050544	arachidonic acid binding(GO:0050544)
0.2	0.8	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.3	GO:0017159	pantetheine hydrolase activity(GO:0017159)
0.1	0.7	GO:0005522	profilin binding(GO:0005522)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.2	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.2	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1	1.1	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	0.5	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.3	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.1	0.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1	0.2	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.1	0.2	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	1.3	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.1	0.2	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.1	0.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.3	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.4	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.3	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.5	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.5	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.1	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.2	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.3	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.0	0.1	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.4	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.5	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.2	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0052834	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.4	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.1	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.3	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	1.1	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0004974	leukotriene receptor activity(GO:0004974)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.5	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.2	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0004849	uridine kinase activity(GO:0004849)
0.0	0.2	GO:0010181	FMN binding(GO:0010181)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.1	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0033612	receptor serine/threonine kinase binding(GO:0033612)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.0	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.0	GO:0034711	inhibin binding(GO:0034711)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.6	GO:0003743	translation initiation factor activity(GO:0003743)
0.0	0.5	GO:0042393	histone binding(GO:0042393)
0.0	0.1	GO:0008171	O-methyltransferase activity(GO:0008171)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.0	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.2	GO:0015665	alcohol transmembrane transporter activity(GO:0015665)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.0	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.0	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0031013	troponin I binding(GO:0031013)
0.0	0.0	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.3	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.5	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.4	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.0	GO:0004428	obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.6	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.1	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0004579	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.5	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.0	GO:0015299	solute:proton antiporter activity(GO:0015299)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.3	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0022884	macromolecule transmembrane transporter activity(GO:0022884)
0.0	0.2	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1	1.8	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	1.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	2.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.0	0.1	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	1.5	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	1.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.4	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.5	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.5	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.3	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.8	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.4	PID FOXO PATHWAY	FoxO family signaling
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.3	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.1	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	0.1	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	1.8	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.6	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	1.4	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.5	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.1	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.3	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.0	0.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.2	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.4	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0	0.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.2	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.8	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	1.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.3	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.4	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.0	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME CD28 CO STIMULATION	Genes involved in CD28 co-stimulation
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.5	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.4	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.5	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.2	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.3	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.0	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.0	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.0	0.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	0.3	REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	Genes involved in RNA Polymerase II Pre-transcription Events
0.0	0.1	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.1	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.2	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor

Results for HOXB7

Z-value: 0.71

Motif logo

Transcription factors associated with HOXB7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXB7 motif across conditions

Conditions sorted by the z-value of the HOXB7 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: