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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXC10_HOXD13

Z-value: 1.44

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Transcription factors associated with HOXC10_HOXD13

Gene Symbol	Gene ID	Gene Info
HOXC10 Ensembl NCBI GeneCards UniProt	ENSG00000180818.4	homeobox C10
HOXD13 Ensembl NCBI GeneCards UniProt	ENSG00000128714.5	homeobox D13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_54378782_54378933	HOXC10	8	0.709282	0.75	1.9e-02	Click!
chr12_54378940_54379308	HOXC10	154	0.459448	0.68	4.2e-02	Click!
chr2_176957854_176958236	HOXD13	426	0.666240	0.85	3.9e-03	Click!
chr2_176958249_176958400	HOXD13	705	0.454662	0.34	3.7e-01	Click!
chr2_176956617_176956768	HOXD13	927	0.349161	0.25	5.2e-01	Click!

Activity of the HOXC10_HOXD13 motif across conditions

Conditions sorted by the z-value of the HOXC10_HOXD13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_114714851_114715858	1.01	RP11-57H14.2		3720	0.26
chr3_32010054_32010475	0.98	OSBPL10	oxysterol binding protein-like 10	12528	0.2
chr12_27296518_27296946	0.91	C12orf71	chromosome 12 open reading frame 71	61285	0.12
chr17_46650833_46651193	0.85	HOXB3	homeobox B3	372	0.67
chr7_27138540_27138742	0.85	HOTAIRM1	HOXA transcript antisense RNA, myeloid-specific 1	183	0.86
chr6_42537305_42537764	0.82	UBR2	ubiquitin protein ligase E3 component n-recognin 2	5734	0.24
chr17_79317268_79317735	0.78	TMEM105	transmembrane protein 105	13027	0.13
chr4_3390510_3390764	0.78	RGS12	regulator of G-protein signaling 12	2576	0.32
chr3_183893852_183894003	0.77	AP2M1	adaptor-related protein complex 2, mu 1 subunit	639	0.55
chr7_134464463_134465343	0.77	CALD1	caldesmon 1	474	0.89
chr10_125607664_125607815	0.77	CPXM2	carboxypeptidase X (M14 family), member 2	43591	0.14
chr17_58821066_58821723	0.74	ENSG00000252534	.	5013	0.22
chr7_27202641_27202952	0.72	HOXA9	homeobox A9	2349	0.09
chr9_684288_685148	0.72	RP11-130C19.3		837	0.67
chr8_49834597_49834856	0.72	SNAI2	snail family zinc finger 2	427	0.91
chr13_27557206_27557734	0.69	USP12-AS1	USP12 antisense RNA 1	179522	0.03
chr15_25638050_25638201	0.67	UBE3A	ubiquitin protein ligase E3A	12528	0.11
chr3_29327656_29328192	0.67	RBMS3-AS3	RBMS3 antisense RNA 3	4293	0.26
chr10_33620428_33620906	0.67	NRP1	neuropilin 1	2643	0.37
chr9_135819104_135820215	0.66	TSC1	tuberous sclerosis 1	349	0.7
chr7_80547175_80548098	0.65	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	863	0.76
chr1_202508681_202509081	0.65	ENSG00000253042	.	12326	0.21
chr7_42036375_42036905	0.64	GLI3	GLI family zinc finger 3	230680	0.02
chr22_45865037_45865472	0.64	RP1-102D24.5		20630	0.17
chr6_27515697_27516098	0.63	ENSG00000206671	.	48294	0.13
chr3_12235413_12235694	0.63	TIMP4	TIMP metallopeptidase inhibitor 4	34702	0.2
chr10_79382855_79383201	0.62	KCNMA1	potassium large conductance calcium-activated channel, subfamily M, alpha member 1	14177	0.23
chr11_14467853_14468182	0.61	ENSG00000251991	.	32421	0.18
chr13_36046333_36046484	0.61	MAB21L1	mab-21-like 1 (C. elegans)	4424	0.23
chr1_210424215_210424840	0.61	SERTAD4-AS1	SERTAD4 antisense RNA 1	17135	0.21
chr1_179111271_179111703	0.60	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr10_4093321_4093737	0.60	KLF6	Kruppel-like factor 6	266056	0.02
chr13_76217437_76217800	0.60	LMO7	LIM domain 7	7159	0.18
chr7_27191312_27191528	0.60	HOXA-AS3	HOXA cluster antisense RNA 3	1749	0.13
chr17_46666677_46666997	0.60	HOXB3	homeobox B3	760	0.3
chr12_54367495_54368083	0.59	HOXC11	homeobox C11	877	0.24
chr20_6764834_6765429	0.59	BMP2	bone morphogenetic protein 2	16820	0.28
chr2_110872434_110873339	0.59	MALL	mal, T-cell differentiation protein-like	713	0.63
chr18_61555576_61555794	0.58	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	692	0.68
chr18_22928819_22929051	0.58	ZNF521	zinc finger protein 521	2222	0.42
chr6_98074983_98075489	0.58	MMS22L	MMS22-like, DNA repair protein	344184	0.01
chr15_49716260_49716444	0.58	FGF7	fibroblast growth factor 7	895	0.66
chr4_114216807_114216958	0.57	ANK2	ankyrin 2, neuronal	2744	0.39
chr13_40139928_40140149	0.57	LHFP	lipoma HMGIC fusion partner	37270	0.18
chr3_178254040_178254903	0.57	KCNMB2	potassium large conductance calcium-activated channel, subfamily M, beta member 2	447	0.9
chr1_200749890_200750160	0.56	CAMSAP2	calmodulin regulated spectrin-associated protein family, member 2	41118	0.17
chr9_12775045_12775253	0.56	LURAP1L	leucine rich adaptor protein 1-like	129	0.97
chr6_147528870_147529159	0.56	STXBP5	syntaxin binding protein 5 (tomosyn)	1904	0.39
chr17_79315981_79316442	0.56	TMEM105	transmembrane protein 105	11737	0.13
chr8_42063953_42065062	0.56	PLAT	plasminogen activator, tissue	576	0.71
chr7_15723868_15724269	0.55	MEOX2	mesenchyme homeobox 2	2369	0.37
chr20_11898508_11899014	0.55	BTBD3	BTB (POZ) domain containing 3	196	0.82
chr4_77506894_77507309	0.55	ENSG00000265314	.	10397	0.17
chr5_2754424_2754575	0.55	C5orf38	chromosome 5 open reading frame 38	2120	0.35
chr4_48728903_48729193	0.54	FRYL	FRY-like	45860	0.16
chr9_12859535_12860149	0.54	ENSG00000222658	.	25478	0.2
chr5_52098501_52098716	0.53	CTD-2288O8.1		14748	0.19
chr2_151385576_151386025	0.53	RND3	Rho family GTPase 3	9725	0.33
chr18_12315444_12315629	0.53	TUBB6	tubulin, beta 6 class V	4570	0.2
chr5_98112819_98113202	0.53	RGMB	repulsive guidance molecule family member b	3671	0.26
chr3_71591333_71591803	0.52	ENSG00000221264	.	328	0.83
chr5_141707476_141707874	0.52	AC005592.2		2812	0.29
chr6_116381607_116382020	0.52	FRK	fyn-related kinase	108	0.97
chr4_175075425_175075781	0.52	FBXO8	F-box protein 8	129211	0.05
chr4_139162325_139164249	0.51	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	216	0.97
chr18_8615592_8616115	0.51	RAB12	RAB12, member RAS oncogene family	6410	0.21
chr1_243414977_243415342	0.51	CEP170	centrosomal protein 170kDa	1463	0.39
chr19_30436184_30436558	0.50	URI1	URI1, prefoldin-like chaperone	2946	0.39
chr5_54456050_54456451	0.50	GPX8	glutathione peroxidase 8 (putative)	252	0.86
chr5_155754238_155754771	0.50	SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	737	0.81
chr6_84139529_84139855	0.50	ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	1072	0.62
chr3_9772097_9772248	0.50	BRPF1	bromodomain and PHD finger containing, 1	1241	0.32
chr13_21590843_21591339	0.50	LATS2-AS1	LATS2 antisense RNA 1	11795	0.14
chr1_114077426_114077577	0.49	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	143890	0.04
chr13_45793788_45794014	0.49	KCTD4	potassium channel tetramerization domain containing 4	18726	0.18
chrX_119596476_119596627	0.49	LAMP2	lysosomal-associated membrane protein 2	6296	0.25
chr19_45995836_45996758	0.49	RTN2	reticulon 2	228	0.87
chr12_66341710_66342532	0.49	RP11-366L20.3		138	0.96
chr10_24756981_24757214	0.48	KIAA1217	KIAA1217	1637	0.45
chr4_148944622_148945028	0.48	RP11-76G10.1		122797	0.06
chr3_127896914_127897065	0.48	RUVBL1	RuvB-like AAA ATPase 1	24232	0.16
chr2_201021102_201021310	0.48	SPATS2L	spermatogenesis associated, serine-rich 2-like	149398	0.04
chr6_144328216_144329081	0.48	PLAGL1	pleiomorphic adenoma gene-like 1	750	0.76
chr2_207998546_207999225	0.47	KLF7	Kruppel-like factor 7 (ubiquitous)	24	0.98
chr13_77457508_77457742	0.47	KCTD12	potassium channel tetramerization domain containing 12	2900	0.26
chr5_98123899_98124050	0.47	RGMB	repulsive guidance molecule family member b	14635	0.21
chr18_20612011_20612377	0.47	ENSG00000223023	.	7635	0.17
chr7_27209745_27210142	0.47	ENSG00000207584	.	760	0.3
chr2_184180506_184180887	0.47	NUP35	nucleoporin 35kDa	191523	0.03
chr8_97940336_97940512	0.47	CPQ	carboxypeptidase Q	101273	0.08
chr17_8532849_8533035	0.47	MYH10	myosin, heavy chain 10, non-muscle	1093	0.57
chr1_235132676_235132959	0.47	ENSG00000239690	.	92884	0.08
chr2_155796209_155796360	0.47	ENSG00000223197	.	149766	0.04
chr18_54046287_54046510	0.47	TXNL1	thioredoxin-like 1	235324	0.02
chr3_29554516_29555025	0.47	RBMS3-AS2	RBMS3 antisense RNA 2	103776	0.08
chr3_175244326_175245006	0.47	ENSG00000201648	.	82601	0.1
chr13_103478539_103479046	0.46	ENSG00000222301	.	6449	0.13
chr4_128553582_128553997	0.46	INTU	inturned planar cell polarity protein	298	0.94
chr9_134554105_134554369	0.46	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	30992	0.18
chr6_162052900_162053180	0.46	ENSG00000221021	.	16942	0.31
chr18_46520644_46520795	0.46	RP11-15F12.1		29354	0.17
chr2_191024581_191024732	0.46	C2orf88	chromosome 2 open reading frame 88	9684	0.24
chr10_30138566_30138997	0.45	SVIL	supervillin	114048	0.06
chr6_152701268_152701555	0.45	SYNE1-AS1	SYNE1 antisense RNA 1	270	0.91
chr1_170631765_170631991	0.45	PRRX1	paired related homeobox 1	397	0.91
chr19_47479063_47479605	0.45	ENSG00000252071	.	27788	0.14
chr1_81703498_81704139	0.45	ENSG00000223026	.	13656	0.28
chr3_72936213_72936412	0.45	GXYLT2	glucoside xylosyltransferase 2	912	0.64
chr4_48024272_48024423	0.45	NIPAL1	NIPA-like domain containing 1	2797	0.23
chr4_152148275_152148426	0.45	SH3D19	SH3 domain containing 19	600	0.77
chr4_15685369_15685921	0.44	FAM200B	family with sequence similarity 200, member B	2216	0.26
chr1_45083000_45083241	0.44	RNF220	ring finger protein 220	8878	0.17
chr17_12453190_12453475	0.44	MYOCD	myocardin	115974	0.06
chr5_14036568_14037099	0.44	DNAH5	dynein, axonemal, heavy chain 5	92181	0.09
chr10_90453154_90453305	0.44	LIPF	lipase, gastric	29014	0.15
chr7_27195553_27195704	0.44	HOXA7	homeobox A7	670	0.38
chr2_9348603_9349207	0.44	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	2011	0.46
chr13_71953108_71953259	0.44	DACH1	dachshund homolog 1 (Drosophila)	487724	0.01
chr2_197852125_197852688	0.44	ANKRD44	ankyrin repeat domain 44	12820	0.25
chr5_110846365_110846666	0.43	STARD4-AS1	STARD4 antisense RNA 1	1409	0.37
chr12_27163427_27163578	0.43	TM7SF3	transmembrane 7 superfamily member 3	2445	0.24
chr10_36638906_36639157	0.43	ENSG00000237002	.	88558	0.1
chr18_24326450_24326792	0.43	ENSG00000265369	.	57128	0.13
chr10_123873011_123873256	0.43	TACC2	transforming, acidic coiled-coil containing protein 2	579	0.84
chr2_66802598_66802990	0.43	MEIS1	Meis homeobox 1	66735	0.13
chr9_97812256_97812766	0.43	ENSG00000207563	.	34979	0.12
chr21_36256728_36257172	0.43	RUNX1	runt-related transcription factor 1	2530	0.42
chr13_78659821_78660303	0.43	RNF219-AS1	RNF219 antisense RNA 1	30772	0.24
chrX_45634159_45634477	0.43	ENSG00000207725	.	27788	0.21
chr11_133989706_133990192	0.43	NCAPD3	non-SMC condensin II complex, subunit D3	48418	0.12
chrX_115371447_115371702	0.43	AGTR2	angiotensin II receptor, type 2	69599	0.13
chr1_60031328_60031726	0.42	FGGY	FGGY carbohydrate kinase domain containing	11937	0.3
chr18_25757173_25757741	0.42	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	47	0.99
chr20_1877591_1877897	0.42	SIRPA	signal-regulatory protein alpha	1802	0.42
chr2_120064088_120064263	0.42	STEAP3-AS1	STEAP3 antisense RNA 1	57528	0.1
chr4_27219592_27219774	0.42	ENSG00000222206	.	5366	0.35
chr1_79043181_79043547	0.42	IFI44L	interferon-induced protein 44-like	42243	0.17
chr9_12775321_12775833	0.42	LURAP1L	leucine rich adaptor protein 1-like	557	0.78
chr5_123734076_123734227	0.42	RP11-436H11.2		330373	0.01
chr14_36741811_36742096	0.42	ENSG00000252312	.	40973	0.15
chr3_12879915_12880160	0.42	ENSG00000207496	.	1912	0.22
chr3_87036535_87037613	0.42	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr6_19691587_19692480	0.42	ENSG00000200957	.	49273	0.18
chr8_104090727_104091208	0.42	ENSG00000265667	.	13982	0.15
chr10_108333794_108333945	0.42	SORCS1	sortilin-related VPS10 domain containing receptor 1	37876	0.24
chr8_92240929_92241217	0.42	SLC26A7	solute carrier family 26 (anion exchanger), member 7	19345	0.19
chr3_157822422_157822707	0.42	SHOX2	short stature homeobox 2	519	0.7
chr10_5045552_5046386	0.41	AKR1C2	aldo-keto reductase family 1, member C2	83	0.93
chr3_153037931_153038307	0.41	ENSG00000265813	.	120313	0.06
chr15_99788624_99789059	0.41	TTC23	tetratricopeptide repeat domain 23	895	0.51
chr1_185373783_185374254	0.41	ENSG00000252407	.	29358	0.21
chr7_14020163_14020323	0.41	ETV1	ets variant 1	5823	0.29
chr1_8600552_8600703	0.41	RERE	arginine-glutamic acid dipeptide (RE) repeats	14541	0.22
chr1_214723042_214723197	0.41	PTPN14	protein tyrosine phosphatase, non-receptor type 14	1447	0.54
chr3_190251616_190251894	0.41	IL1RAP	interleukin 1 receptor accessory protein	19864	0.24
chr14_85707273_85707789	0.41	ENSG00000252529	.	30745	0.26
chr8_141909083_141909234	0.41	PTK2	protein tyrosine kinase 2	8291	0.26
chr2_189843684_189844024	0.40	ENSG00000221502	.	1036	0.57
chrX_135230667_135231011	0.40	FHL1	four and a half LIM domains 1	102	0.97
chr14_27067583_27067941	0.40	NOVA1-AS1	NOVA1 antisense RNA 1 (head to head)	144	0.9
chr15_59598169_59598320	0.40	RP11-429D19.1		34883	0.11
chr11_121968787_121969071	0.40	ENSG00000207971	.	1623	0.3
chr2_194549981_194550132	0.40	ENSG00000264560	.	872942	0.0
chr18_59263038_59263245	0.40	CDH20	cadherin 20, type 2	46042	0.2
chr17_45959589_45959832	0.40	SP2	Sp2 transcription factor	13806	0.1
chr7_134465998_134466492	0.40	CALD1	caldesmon 1	1816	0.49
chr6_100780246_100780397	0.40	RP1-121G13.2		94673	0.09
chr11_103395337_103395488	0.40	DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	166441	0.04
chr18_9615856_9616007	0.40	PPP4R1	protein phosphatase 4, regulatory subunit 1	693	0.62
chr13_50649761_50650212	0.40	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	6321	0.18
chr10_24740047_24740337	0.40	KIAA1217	KIAA1217	1830	0.43
chr2_160470923_160471074	0.40	AC009506.1		809	0.5
chr7_130602447_130602598	0.40	ENSG00000226380	.	40224	0.17
chr6_138427325_138427625	0.39	PERP	PERP, TP53 apoptosis effector	1173	0.59
chr3_167814440_167814591	0.39	GOLIM4	golgi integral membrane protein 4	752	0.79
chr3_64162488_64162731	0.39	PRICKLE2-AS3	PRICKLE2 antisense RNA 3	10611	0.2
chr3_190415622_190416004	0.39	ENSG00000223117	.	55861	0.15
chr4_32149221_32149372	0.39	NA	NA	> 10⁶	NA
chr13_80912572_80913077	0.39	SPRY2	sprouty homolog 2 (Drosophila)	970	0.67
chr17_79533812_79534253	0.39	NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	371	0.75
chr4_154434446_154434929	0.39	KIAA0922	KIAA0922	42361	0.17
chr2_188418561_188419245	0.39	AC007319.1		27	0.69
chr17_79376467_79376892	0.39	ENSG00000266392	.	2101	0.19
chr11_95890029_95890311	0.39	ENSG00000266192	.	184432	0.03
chr15_99790169_99790383	0.39	TTC23	tetratricopeptide repeat domain 23	461	0.71
chr12_66274639_66274849	0.39	RP11-366L20.2	Uncharacterized protein	614	0.73
chr22_36233928_36234199	0.39	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2202	0.43
chr15_37394480_37395011	0.39	MEIS2	Meis homeobox 2	1241	0.49
chr4_87516254_87516849	0.39	PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	295	0.87
chr18_52988378_52989650	0.38	TCF4	transcription factor 4	203	0.97
chr6_53928552_53928746	0.38	MLIP-AS1	MLIP antisense RNA 1	15875	0.2
chr5_123991499_123991730	0.38	RP11-436H11.2		72910	0.09
chr4_177192376_177192684	0.38	ASB5	ankyrin repeat and SOCS box containing 5	2157	0.35
chr1_159931930_159932191	0.38	SLAMF9	SLAM family member 9	8016	0.12
chr11_78271810_78272407	0.38	NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	12467	0.18
chr2_225746955_225747106	0.38	DOCK10	dedicator of cytokinesis 10	64752	0.15
chr12_109090441_109090824	0.38	CORO1C	coronin, actin binding protein, 1C	454	0.79
chr3_100660155_100660398	0.38	ENSG00000201642	.	11195	0.24
chr2_134432207_134432889	0.38	ENSG00000200708	.	78886	0.11
chr3_178684614_178685138	0.38	ZMAT3	zinc finger, matrin-type 3	104478	0.06

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC10_HOXD13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.2	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3	1.1	GO:0060437	lung growth(GO:0060437)
0.2	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.7	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.9	GO:0060013	righting reflex(GO:0060013)
0.2	0.8	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.6	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.6	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.4	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.2	0.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.4	GO:0060594	mammary gland specification(GO:0060594)
0.2	0.6	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	0.5	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	0.5	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2	0.2	GO:0071481	cellular response to X-ray(GO:0071481)
0.2	0.3	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.4	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.1	0.3	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.4	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.4	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.1	0.6	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.3	GO:0060435	bronchiole development(GO:0060435)
0.1	0.6	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.8	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.1	0.4	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.5	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.4	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	0.3	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1	0.3	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.1	0.3	GO:2001280	regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1	2.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.4	GO:0016266	O-glycan processing(GO:0016266)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.5	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.3	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.4	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.1	GO:0031223	auditory behavior(GO:0031223)
0.1	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.6	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.1	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.1	0.7	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.3	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.3	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1	0.3	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.2	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.4	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	1.8	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.4	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.3	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.5	GO:0048844	artery morphogenesis(GO:0048844)
0.1	0.4	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.2	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0051940	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.8	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.1	0.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.1	0.4	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.3	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.4	GO:0032288	myelin assembly(GO:0032288)
0.1	0.1	GO:0007021	tubulin complex assembly(GO:0007021)
0.1	0.2	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.1	GO:0035850	epithelial cell differentiation involved in kidney development(GO:0035850)
0.1	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0003308	negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.8	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.1	0.3	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	1.1	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.3	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.5	GO:0019228	neuronal action potential(GO:0019228)
0.1	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.2	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.2	GO:0000966	RNA 5'-end processing(GO:0000966)
0.1	0.8	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.1	0.2	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.1	GO:0010193	response to ozone(GO:0010193)
0.1	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.2	GO:0008218	bioluminescence(GO:0008218)
0.1	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.2	GO:0010955	negative regulation of protein processing(GO:0010955) negative regulation of complement activation(GO:0045916) negative regulation of protein maturation(GO:1903318) negative regulation of protein activation cascade(GO:2000258)
0.1	1.2	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.1	GO:1902339	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.2	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.2	GO:0002138	retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.0	0.4	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.2	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.2	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.2	GO:0014741	negative regulation of muscle hypertrophy(GO:0014741)
0.0	0.2	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.2	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.5	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0061047	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.2	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.2	GO:0060039	pericardium development(GO:0060039)
0.0	0.8	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	1.3	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0	0.0	GO:0060535	trachea morphogenesis(GO:0060439) trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:0001839	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0060027	convergent extension involved in gastrulation(GO:0060027)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.4	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.1	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.3	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0010765	positive regulation of sodium ion transport(GO:0010765)
0.0	0.6	GO:0008038	neuron recognition(GO:0008038)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.1	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0	0.4	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0002446	neutrophil mediated immunity(GO:0002446)
0.0	0.1	GO:0097531	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.2	GO:0007625	grooming behavior(GO:0007625)
0.0	0.1	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.3	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.0	0.1	GO:0072599	protein targeting to ER(GO:0045047) establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.0	0.3	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0032364	oxygen homeostasis(GO:0032364)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0051026	chiasma assembly(GO:0051026)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.1	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.0	0.1	GO:0051290	protein heterotetramerization(GO:0051290)
0.0	0.0	GO:0007412	axon target recognition(GO:0007412)
0.0	0.0	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.2	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.0	0.2	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.5	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.0	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.0	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.2	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0051818	disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.2	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.0	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.0	GO:0060592	mammary gland formation(GO:0060592)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.4	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.2	GO:0033280	response to vitamin D(GO:0033280)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0072172	mesonephric tubule formation(GO:0072172)
0.0	0.1	GO:0003156	regulation of organ formation(GO:0003156)
0.0	0.1	GO:0019532	oxalate transport(GO:0019532)
0.0	0.2	GO:0021988	olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0	0.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0045143	synapsis(GO:0007129) homologous chromosome segregation(GO:0045143) chromosome organization involved in meiotic cell cycle(GO:0070192)
0.0	0.2	GO:0015693	magnesium ion transport(GO:0015693)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0003160	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160) endocardium formation(GO:0060214)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0030033	microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0	0.0	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.2	GO:0006693	prostaglandin metabolic process(GO:0006693)
0.0	0.1	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.2	GO:0098856	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.0	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.0	GO:0010658	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.1	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.3	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.0	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0	0.1	GO:0009651	response to salt stress(GO:0009651)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	0.0	GO:0034653	vitamin catabolic process(GO:0009111) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.0	GO:0009415	response to water(GO:0009415)
0.0	0.0	GO:0060026	convergent extension(GO:0060026)
0.0	0.0	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.2	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.1	GO:0006622	protein targeting to lysosome(GO:0006622) protein targeting to vacuole(GO:0006623) protein localization to lysosome(GO:0061462) protein localization to vacuole(GO:0072665) establishment of protein localization to vacuole(GO:0072666)
0.0	0.6	GO:0045444	fat cell differentiation(GO:0045444)
0.0	0.2	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.0	GO:0017000	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0071224	cellular response to peptidoglycan(GO:0071224)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.1	GO:0007143	female meiotic division(GO:0007143)
0.0	1.6	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.0	GO:0070841	inclusion body assembly(GO:0070841) aggresome assembly(GO:0070842)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.0	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.0	GO:0045713	low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0007435	salivary gland morphogenesis(GO:0007435)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.2	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.0	GO:0005997	xylulose metabolic process(GO:0005997)
0.0	0.1	GO:0009886	post-embryonic morphogenesis(GO:0009886)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0045006	DNA deamination(GO:0045006)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.1	GO:0009820	alkaloid metabolic process(GO:0009820)
0.0	0.2	GO:0043525	positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.0	GO:0035092	sperm chromatin condensation(GO:0035092)
0.0	0.0	GO:0018243	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle organ development(GO:0048635) negative regulation of muscle tissue development(GO:1901862)
0.0	0.0	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.1	GO:0071385	cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.2	GO:0048704	embryonic skeletal system morphogenesis(GO:0048704)
0.0	0.1	GO:0006228	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.0	0.0	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.0	GO:0001993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine(GO:0001993)
0.0	0.2	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.8	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.1	GO:0001508	action potential(GO:0001508)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0019614	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.3	GO:0006749	glutathione metabolic process(GO:0006749)
0.0	0.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.1	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	0.7	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.5	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.5	GO:0043218	compact myelin(GO:0043218)
0.1	0.6	GO:0071437	invadopodium(GO:0071437)
0.1	1.3	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.6	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.8	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.6	GO:0010369	chromocenter(GO:0010369)
0.1	0.6	GO:0005916	fascia adherens(GO:0005916)
0.1	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.1	0.2	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0000801	central element(GO:0000801)
0.1	0.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.7	GO:0043256	laminin complex(GO:0043256)
0.1	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.9	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.6	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0	0.2	GO:0005581	collagen trimer(GO:0005581)
0.0	0.2	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.3	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	2.0	GO:0030426	growth cone(GO:0030426)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	1.4	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.2	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.5	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0098644	complex of collagen trimers(GO:0098644)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0043205	fibril(GO:0043205)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	2.2	GO:0043292	contractile fiber(GO:0043292)
0.0	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.2	GO:0030315	T-tubule(GO:0030315)
0.0	5.5	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.3	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.4	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.0	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	1.1	GO:0005923	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0031941	filamentous actin(GO:0031941)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.4	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.6	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.1	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.3	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.8	GO:0005911	cell-cell junction(GO:0005911)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3	0.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	0.7	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.2	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.2	0.7	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.7	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.2	0.5	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.6	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	1.9	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	0.4	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.9	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.3	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.4	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.4	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1	0.3	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.5	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	1.1	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.4	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	0.3	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.4	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.2	GO:0008061	chitin binding(GO:0008061)
0.1	0.4	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.7	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.3	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.1	0.4	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	2.0	GO:0005518	collagen binding(GO:0005518)
0.1	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.7	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.3	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.4	GO:0051378	serotonin binding(GO:0051378)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
0.0	0.4	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	1.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.2	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0	0.6	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.2	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0004938	alpha-adrenergic receptor activity(GO:0004936) alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	1.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	5.8	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	1.1	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.2	GO:0015101	organic cation transmembrane transporter activity(GO:0015101)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.2	GO:0015197	peptide transporter activity(GO:0015197)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.5	GO:0042562	hormone binding(GO:0042562)
0.0	0.8	GO:0051015	actin filament binding(GO:0051015)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.0	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	1.6	GO:0008083	growth factor activity(GO:0008083)
0.0	0.1	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.0	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.4	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	0.1	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0000832	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832)
0.0	0.1	GO:0043498	obsolete cell surface binding(GO:0043498)
0.0	0.0	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.4	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.0	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0071617	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0	0.7	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0008048	calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0	0.0	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0	0.3	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.2	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	ST ADRENERGIC	Adrenergic Pathway
0.1	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.1	0.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	1.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	2.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.0	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	1.3	PID FGF PATHWAY	FGF signaling pathway
0.0	0.6	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.9	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.0	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	1.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.7	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.6	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.3	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID ARF 3PATHWAY	Arf1 pathway
0.0	2.5	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.6	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.0	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
0.0	0.1	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.3	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.3	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.4	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	2.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	1.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.9	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	1.3	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.0	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	2.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.6	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.7	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.8	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.1	REACTOME IL 3 5 AND GM CSF SIGNALING	Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0	0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME GABA RECEPTOR ACTIVATION	Genes involved in GABA receptor activation
0.0	0.2	REACTOME OPIOID SIGNALLING	Genes involved in Opioid Signalling
0.0	0.5	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.1	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.4	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.0	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.1	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.0	REACTOME SIGNAL AMPLIFICATION	Genes involved in Signal amplification
0.0	0.3	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.1	REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM	Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism
0.0	0.2	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis

Results for HOXC10_HOXD13

Z-value: 1.44

Motif logo

Transcription factors associated with HOXC10_HOXD13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXC10_HOXD13 motif across conditions

Conditions sorted by the z-value of the HOXC10_HOXD13 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC10_HOXD13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: