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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXC11

Z-value: 0.22

Motif logo

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Transcription factors associated with HOXC11

Gene Symbol Gene ID Gene Info
HOXC11
ENSG00000123388.4 homeobox C11

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_54366652_54366803HOXC111830.8273880.314.1e-01Click!
chr12_54367124_54367311HOXC113050.6910510.314.2e-01Click!
chr12_54366891_54367088HOXC11770.9017020.206.0e-01Click!
chr12_54367495_54368083HOXC118770.242171-0.196.2e-01Click!

Activity of the HOXC11 motif across conditions

Conditions sorted by the z-value of the HOXC11 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr3_183893852_183894003 0.11 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
 639
 0.55
chr7_121514140_121514423 0.09 PTPRZ1
 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
 866
 0.74
chr2_213977055_213977206 0.09 IKZF2
 IKAROS family zinc finger 2 (Helios)
 36223
 0.21
chr7_27138540_27138742 0.09 HOTAIRM1
 HOXA transcript antisense RNA, myeloid-specific 1
 183
 0.86
chr2_151385576_151386025 0.09 RND3
 Rho family GTPase 3
 9725
 0.33
chr2_184180506_184180887 0.08 NUP35
 nucleoporin 35kDa
 191523
 0.03
chr6_128529501_128529738 0.08 PTPRK
 protein tyrosine phosphatase, receptor type, K
 113707
 0.07
chr1_170631765_170631991 0.07 PRRX1
 paired related homeobox 1
 397
 0.91
chr10_89686715_89686866 0.07 RP11-380G5.2
48341
 0.12
chr12_56308297_56308448 0.07 WIBG
 within bgcn homolog (Drosophila)
 12524
 0.09
chr19_4059827_4060036 0.07 CTD-2622I13.3
2816
 0.16
chr4_163496269_163496420 0.06 FSTL5
 follistatin-like 5
 411157
 0.01
chr3_116755274_116755493 0.06 ENSG00000200372
 .
 71309
 0.12
chr10_104253427_104253578 0.06 ACTR1A
 ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
 8933
 0.1
chr4_39570973_39571124 0.06 UGDH
 UDP-glucose 6-dehydrogenase
 41117
 0.11
chr8_83181283_83181434 0.06 SNX16
 sorting nexin 16
 426257
 0.01
chr8_42063953_42065062 0.06 PLAT
 plasminogen activator, tissue
 576
 0.71
chr13_107382919_107383070 0.06 ARGLU1
 arginine and glutamate rich 1
 162482
 0.04
chr14_81453709_81453897 0.06 CEP128
 centrosomal protein 128kDa
 27955
 0.21
chr11_22380798_22380949 0.06 CTD-2140G10.4
2967
 0.27
chr3_29327656_29328192 0.06 RBMS3-AS3
 RBMS3 antisense RNA 3
 4293
 0.26
chr8_91782901_91783052 0.05 NECAB1
 N-terminal EF-hand calcium binding protein 1
 20802
 0.19
chr9_81871537_81871846 0.05 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 314997
 0.01
chr17_32078540_32078804 0.05 ENSG00000221699
 .
 122805
 0.05
chr10_120966033_120966362 0.05 GRK5
 G protein-coupled receptor kinase 5
 904
 0.45
chrX_31284117_31284268 0.05 DMD
 dystrophin
 782
 0.77
chr9_133814218_133814626 0.05 FIBCD1
 fibrinogen C domain containing 1
 33
 0.97
chr1_178310607_178310919 0.05 RASAL2
 RAS protein activator like 2
 157
 0.97
chr1_216897072_216897310 0.05 ESRRG
 estrogen-related receptor gamma
 396
 0.93
chr5_67483384_67483535 0.05 RP11-404L6.2
 Uncharacterized protein
 2245
 0.34
chr11_94671451_94671602 0.05 RP11-856F16.2
12840
 0.19
chr13_32859694_32859925 0.05 FRY
 furry homolog (Drosophila)
 2179
 0.28
chr6_108486676_108487297 0.04 OSTM1
 osteopetrosis associated transmembrane protein 1
 58
 0.78
chr20_52517333_52517726 0.04 AC005220.3
39170
 0.2
chr20_11882046_11882285 0.04 BTBD3
 BTB (POZ) domain containing 3
 9024
 0.24
chr3_168890820_168890971 0.04 MECOM
 MDS1 and EVI1 complex locus
 25373
 0.27
chr10_24756981_24757214 0.04 KIAA1217
 KIAA1217
 1637
 0.45
chr5_58412336_58412487 0.04 RP11-266N13.2
76823
 0.11
chr12_93515628_93515779 0.04 RP11-511B23.2
17164
 0.2
chr5_145319076_145319227 0.04 SH3RF2
 SH3 domain containing ring finger 2
 1711
 0.46
chr12_11325045_11325196 0.04 RP11-785H5.2
1168
 0.4
chr8_8745358_8745509 0.04 MFHAS1
 malignant fibrous histiocytoma amplified sequence 1
 5722
 0.22
chr9_20511940_20512213 0.04 ENSG00000264941
 .
 9736
 0.23
chr14_85707273_85707789 0.04 ENSG00000252529
 .
 30745
 0.26
chr17_79315981_79316442 0.04 TMEM105
 transmembrane protein 105
 11737
 0.13
chr12_96184496_96184659 0.04 NTN4
 netrin 4
 35
 0.97
chr10_83723729_83723880 0.04 NRG3
 neuregulin 3
 86087
 0.1
chr4_36534650_36534801 0.04 RP11-431M7.2
140693
 0.05
chr5_112822732_112823004 0.04 MCC
 mutated in colorectal cancers
 1659
 0.35
chr15_93428286_93428633 0.04 CHD2
 chromodomain helicase DNA binding protein 2
 1933
 0.32
chr2_198572573_198572724 0.04 MARS2
 methionyl-tRNA synthetase 2, mitochondrial
 2561
 0.27
chr15_25637624_25637775 0.04 UBE3A
 ubiquitin protein ligase E3A
 12954
 0.11
chr3_15823018_15823169 0.04 ANKRD28
 ankyrin repeat domain 28
 14935
 0.19
chr1_70768783_70768934 0.04 ANKRD13C
 ankyrin repeat domain 13C
 51547
 0.11
chr2_222287657_222287808 0.04 EPHA4
 EPH receptor A4
 79548
 0.11
chr4_153269690_153269947 0.04 FBXW7
 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
 140
 0.97
chr11_79150724_79151047 0.04 TENM4
 teneurin transmembrane protein 4
 810
 0.68
chr17_62971851_62972399 0.04 AMZ2P1
 archaelysin family metallopeptidase 2 pseudogene 1
 2490
 0.23
chr10_22899285_22899436 0.04 PIP4K2A
 phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
 18718
 0.27
chr8_49321315_49321611 0.04 ENSG00000252710
 .
 100873
 0.08
chr9_12859535_12860149 0.04 ENSG00000222658
 .
 25478
 0.2
chr4_26240703_26241213 0.04 RBPJ
 recombination signal binding protein for immunoglobulin kappa J region
 33271
 0.24
chr3_49538097_49538499 0.04 DAG1
 dystroglycan 1 (dystrophin-associated glycoprotein 1)
 30546
 0.11
chr12_86228304_86228474 0.04 RASSF9
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
 1959
 0.44
chr15_48739773_48739924 0.04 DUT
 deoxyuridine triphosphatase
 115245
 0.05
chr6_113966553_113966868 0.04 ENSG00000266650
 .
 42593
 0.17
chr1_115711115_115711431 0.04 TSPAN2
 tetraspanin 2
 79152
 0.1
chr11_77072652_77072803 0.04 PAK1
 p21 protein (Cdc42/Rac)-activated kinase 1
 12395
 0.24
chr6_153911669_153911820 0.04 ENSG00000199246
 .
 90838
 0.09
chr3_151743926_151744077 0.04 RP11-454C18.2
98038
 0.08
chr5_57751342_57751690 0.04 PLK2
 polo-like kinase 2
 4571
 0.26
chr13_43649218_43649369 0.04 DNAJC15
 DnaJ (Hsp40) homolog, subfamily C, member 15
 51954
 0.17
chr14_77998583_77998734 0.04 ENSG00000240233
 .
 15554
 0.15
chr13_80511227_80511398 0.03 SPRY2
 sprouty homolog 2 (Drosophila)
 402482
 0.01
chr2_166477820_166478090 0.03 CSRNP3
 cysteine-serine-rich nuclear protein 3
 47336
 0.18
chr9_101891255_101891406 0.03 TGFBR1
 transforming growth factor, beta receptor 1
 1114
 0.52
chr9_12775321_12775833 0.03 LURAP1L
 leucine rich adaptor protein 1-like
 557
 0.78
chr1_224690897_224691172 0.03 WDR26
 WD repeat domain 26
 66299
 0.1
chr6_167539321_167539472 0.03 CCR6
 chemokine (C-C motif) receptor 6
 3137
 0.25
chr9_100173959_100174113 0.03 TDRD7
 tudor domain containing 7
 196
 0.95
chr6_53928552_53928746 0.03 MLIP-AS1
 MLIP antisense RNA 1
 15875
 0.2
chr2_121716938_121717089 0.03 ENSG00000221321
 .
 75636
 0.11
chr17_55131735_55131912 0.03 AKAP1
 A kinase (PRKA) anchor protein 1
 30630
 0.13
chrX_15965760_15965911 0.03 ENSG00000200566
 .
 31409
 0.2
chr3_104994911_104995062 0.03 ALCAM
 activated leukocyte cell adhesion molecule
 90767
 0.1
chr1_83031111_83031295 0.03 LPHN2
 latrophilin 2
 585630
 0.0
chr10_4174092_4174250 0.03 KLF6
 Kruppel-like factor 6
 346698
 0.01
chr10_33620428_33620906 0.03 NRP1
 neuropilin 1
 2643
 0.37
chr6_56598112_56598263 0.03 DST
 dystonin
 52490
 0.16
chr5_143300598_143300749 0.03 HMHB1
 histocompatibility (minor) HB-1
 108947
 0.07
chr14_89507425_89507846 0.03 FOXN3
 forkhead box N3
 139453
 0.05
chr10_62174410_62174561 0.03 ANK3
 ankyrin 3, node of Ranvier (ankyrin G)
 24997
 0.28
chr12_95606332_95606483 0.03 FGD6
 FYVE, RhoGEF and PH domain containing 6
 4748
 0.2
chr5_180676019_180676390 0.03 GNB2L1
 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
 1108
 0.22
chr22_25507961_25508112 0.03 CTA-221G9.11
623
 0.77
chr11_111381371_111381522 0.03 BTG4
 B-cell translocation gene 4
 1618
 0.2
chr6_3501213_3501364 0.03 SLC22A23
 solute carrier family 22, member 23
 44032
 0.18
chr8_97583871_97584022 0.03 SDC2
 syndecan 2
 8631
 0.28
chr2_213976639_213976790 0.03 IKZF2
 IKAROS family zinc finger 2 (Helios)
 36639
 0.21
chr2_134432207_134432889 0.03 ENSG00000200708
 .
 78886
 0.11
chr5_32164159_32164310 0.03 GOLPH3
 golgi phosphoprotein 3 (coat-protein)
 10222
 0.19
chr16_81577563_81578015 0.03 CMIP
 c-Maf inducing protein
 48835
 0.17
chr5_110846365_110846666 0.03 STARD4-AS1
 STARD4 antisense RNA 1
 1409
 0.37
chr19_4717454_4717717 0.03 DPP9
 dipeptidyl-peptidase 9
 315
 0.83
chr22_36291410_36291691 0.03 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 43395
 0.19
chr4_139160727_139161292 0.03 SLC7A11
 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
 2494
 0.42
chr15_69367071_69367289 0.03 RP11-809H16.4
31275
 0.17
chr5_124748322_124748473 0.03 ENSG00000222107
 .
 61573
 0.16
chr15_26273691_26273918 0.03 ENSG00000212604
 .
 19583
 0.26
chr6_111947186_111947610 0.03 TRAF3IP2
 TRAF3 interacting protein 2
 19917
 0.16
chr12_123210436_123210665 0.03 HCAR1
 hydroxycarboxylic acid receptor 1
 4579
 0.15
chr10_131323764_131323955 0.03 AL355531.2
 Uncharacterized protein
 14334
 0.23
chr18_7958694_7958932 0.03 PTPRM
 protein tyrosine phosphatase, receptor type, M
 11861
 0.23
chrX_151140998_151141149 0.03 GABRE
 gamma-aminobutyric acid (GABA) A receptor, epsilon
 2070
 0.24
chr15_38361508_38361698 0.03 TMCO5A
 transmembrane and coiled-coil domains 5A
 134145
 0.05
chr12_80329810_80330005 0.03 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 667
 0.6
chr1_115820493_115820644 0.03 RP4-663N10.1
5087
 0.3
chr3_37031282_37031460 0.03 EPM2AIP1
 EPM2A (laforin) interacting protein 1
 3424
 0.2
chr16_68299633_68299784 0.03 SLC7A6
 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
 289
 0.77
chr1_94789725_94789884 0.03 ARHGAP29
 Rho GTPase activating protein 29
 86615
 0.08
chr1_172327726_172327959 0.03 ENSG00000206684
 .
 7838
 0.18
chr4_40059743_40060131 0.03 N4BP2
 NEDD4 binding protein 2
 1381
 0.41
chr11_89113858_89114276 0.03 NOX4
 NADPH oxidase 4
 109833
 0.07
chr16_80181289_80181449 0.03 DYNLRB2
 dynein, light chain, roadblock-type 2
 393262
 0.01
chr17_55372937_55373088 0.03 MSI2
 musashi RNA-binding protein 2
 966
 0.68
chr4_85420275_85420452 0.03 NKX6-1
 NK6 homeobox 1
 760
 0.77
chr16_73089798_73090050 0.03 ZFHX3
 zinc finger homeobox 3
 3673
 0.28
chr1_218524044_218525060 0.03 TGFB2
 transforming growth factor, beta 2
 4975
 0.24
chr18_20612011_20612377 0.03 ENSG00000223023
 .
 7635
 0.17
chr11_82904254_82904445 0.03 ANKRD42
 ankyrin repeat domain 42
 432
 0.8
chr8_103664786_103665058 0.03 KLF10
 Kruppel-like factor 10
 1681
 0.44
chr21_16429371_16429522 0.03 NRIP1
 nuclear receptor interacting protein 1
 7680
 0.28
chr14_23448905_23449056 0.03 AJUBA
 ajuba LIM protein
 1815
 0.14
chr4_169752801_169753072 0.03 PALLD
 palladin, cytoskeletal associated protein
 220
 0.9
chr2_27861313_27861464 0.03 ENSG00000206731
 .
 3648
 0.13
chrX_78666635_78666786 0.03 ITM2A
 integral membrane protein 2A
 43661
 0.22
chr16_48641989_48642140 0.03 N4BP1
 NEDD4 binding protein 1
 2056
 0.33
chr6_125401116_125401267 0.03 RNF217
 ring finger protein 217
 31833
 0.2
chr18_19753166_19753317 0.03 GATA6
 GATA binding protein 6
 2347
 0.21
chr2_85196569_85196904 0.03 KCMF1
 potassium channel modulatory factor 1
 1480
 0.46
chr2_235167151_235167323 0.03 SPP2
 secreted phosphoprotein 2, 24kDa
 207806
 0.02
chr3_114225259_114225410 0.03 ZBTB20
 zinc finger and BTB domain containing 20
 51670
 0.16
chr1_159931930_159932191 0.03 SLAMF9
 SLAM family member 9
 8016
 0.12
chr5_53386895_53387046 0.03 ENSG00000265421
 .
 15557
 0.24
chr3_191048468_191048928 0.03 UTS2B
 urotensin 2B
 373
 0.85
chr10_116634887_116635113 0.03 FAM160B1
 family with sequence similarity 160, member B1
 14450
 0.25
chr17_814224_814439 0.03 RP11-676J12.7
 Uncharacterized protein
 1459
 0.38
chr6_17914331_17914482 0.03 KIF13A
 kinesin family member 13A
 73288
 0.11
chr22_24114508_24114741 0.03 MMP11
 matrix metallopeptidase 11 (stromelysin 3)
 382
 0.71
chr17_4135715_4135866 0.03 ANKFY1
 ankyrin repeat and FYVE domain containing 1
 31352
 0.12
chr1_241271770_241271921 0.03 ENSG00000265831
 .
 23727
 0.23
chr13_21654404_21654812 0.03 LATS2
 large tumor suppressor kinase 2
 18922
 0.14
chr3_81724848_81724999 0.03 GBE1
 glucan (1,4-alpha-), branching enzyme 1
 67857
 0.14
chr3_64149261_64149412 0.03 PRICKLE2-AS3
 PRICKLE2 antisense RNA 3
 23884
 0.16
chr4_114367456_114367607 0.03 ENSG00000206820
 .
 26052
 0.18
chr8_34689780_34689931 0.03 ENSG00000265560
 .
 137869
 0.05
chr13_20844899_20845050 0.03 GJB6
 gap junction protein, beta 6, 30kDa
 38440
 0.17
chr11_11472823_11472974 0.03 CSNK2A3
 casein kinase 2, alpha 3 polypeptide
 97994
 0.07
chr11_89955284_89955841 0.03 CHORDC1
 cysteine and histidine-rich domain (CHORD) containing 1
 665
 0.79
chr18_55889348_55889572 0.03 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 657
 0.77
chr6_17413520_17413671 0.03 CAP2
 CAP, adenylate cyclase-associated protein, 2 (yeast)
 19652
 0.26
chr5_60728941_60729092 0.03 ZSWIM6
 zinc finger, SWIM-type containing 6
 100916
 0.08
chr7_141628433_141628584 0.03 OR9A4
 olfactory receptor, family 9, subfamily A, member 4
 9891
 0.12
chr15_99788624_99789059 0.03 TTC23
 tetratricopeptide repeat domain 23
 895
 0.51
chr16_80603632_80603783 0.03 RP11-525K10.3
6675
 0.18
chr2_166802065_166802216 0.03 TTC21B
 tetratricopeptide repeat domain 21B
 8213
 0.19
chr6_21417907_21418058 0.03 SOX4
 SRY (sex determining region Y)-box 4
 175990
 0.04
chrX_119596476_119596627 0.03 LAMP2
 lysosomal-associated membrane protein 2
 6296
 0.25
chr8_94859053_94859497 0.03 TMEM67
 transmembrane protein 67
 61778
 0.09
chr20_6764834_6765429 0.03 BMP2
 bone morphogenetic protein 2
 16820
 0.28
chr13_44389557_44389806 0.03 ENOX1
 ecto-NOX disulfide-thiol exchanger 1
 28637
 0.21
chr13_30002091_30002575 0.03 MTUS2
 microtubule associated tumor suppressor candidate 2
 431
 0.89
chr3_39448821_39449415 0.03 ENSG00000206760
 .
 762
 0.4
chr7_25896786_25897110 0.03 ENSG00000199085
 .
 92658
 0.09
chr17_57699008_57699159 0.03 CLTC
 clathrin, heavy chain (Hc)
 1790
 0.37
chr6_54564223_54564374 0.02 ENSG00000251946
 .
 86887
 0.1
chr4_83787091_83787242 0.02 SEC31A
 SEC31 homolog A (S. cerevisiae)
 918
 0.55
chr13_99629621_99629906 0.02 DOCK9
 dedicator of cytokinesis 9
 481
 0.85
chr5_114868008_114868159 0.02 FEM1C
 fem-1 homolog c (C. elegans)
 12508
 0.22
chr19_45995836_45996758 0.02 RTN2
 reticulon 2
 228
 0.87
chr4_14728626_14728777 0.02 ENSG00000202449
 .
 36367
 0.24
chrX_73068432_73068583 0.02 RP13-216E22.5
120813
 0.06
chr14_45367367_45367627 0.02 C14orf28
 chromosome 14 open reading frame 28
 959
 0.41
chr11_27486888_27487039 0.02 RP11-159H22.2
6313
 0.18
chr3_160700419_160700570 0.02 B3GALNT1
 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
 118461
 0.06
chr15_71054590_71054766 0.02 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 1091
 0.55
chr9_132175724_132175951 0.02 ENSG00000242281
 .
 43097
 0.14
chr16_20922292_20922443 0.02 LYRM1
 LYR motif containing 1
 9941
 0.16
chr11_94441338_94441489 0.02 AMOTL1
 angiomotin like 1
 1816
 0.4
chr17_62648329_62648480 0.02 SMURF2
 SMAD specific E3 ubiquitin protein ligase 2
 9626
 0.22
chr8_10268256_10268407 0.02 RP11-981G7.1
22851
 0.2
chr10_8315388_8315539 0.02 GATA3
 GATA binding protein 3
 218694
 0.02
chr16_50400842_50400993 0.02 RP11-21B23.1
1574
 0.3
chr7_17977598_17977749 0.02 SNX13
 sorting nexin 13
 2418
 0.38
chr3_120168336_120168615 0.02 FSTL1
 follistatin-like 1
 1363
 0.54
chr1_23476622_23476773 0.02 ENSG00000206935
 .
 12500
 0.13
chr5_128796123_128796371 0.02 ADAMTS19-AS1
 ADAMTS19 antisense RNA 1
 135
 0.71
chr18_21418407_21418558 0.02 LAMA3
 laminin, alpha 3
 4565
 0.28
chr14_96681269_96681420 0.02 RP11-404P21.5
4147
 0.14
chr12_64480628_64481033 0.02 RP11-196H14.2
10568
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC11

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0035426 extracellular matrix-cell signaling(GO:0035426)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)