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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXC12_HOXD12

Z-value: 1.42

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Transcription factors associated with HOXC12_HOXD12

Gene Symbol Gene ID Gene Info
HOXC12
ENSG00000123407.3 homeobox C12
HOXD12
ENSG00000170178.5 homeobox D12

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_54344046_54344197HOXC1244970.084649-0.481.9e-01Click!
chr12_54348806_54348957HOXC122630.784258-0.481.9e-01Click!
chr12_54349321_54349472HOXC127780.371124-0.432.5e-01Click!
chr12_54349650_54349801HOXC1211070.249164-0.373.3e-01Click!
chr12_54347104_54347382HOXC1213750.198326-0.206.0e-01Click!
chr2_176961450_176961876HOXD1227950.1151680.491.8e-01Click!
chr2_176961922_176962434HOXD1222800.133461-0.284.7e-01Click!
chr2_176961216_176961367HOXD1231670.1066970.166.8e-01Click!

Activity of the HOXC12_HOXD12 motif across conditions

Conditions sorted by the z-value of the HOXC12_HOXD12 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_161992740_161992891 0.73 OLFML2B
 olfactomedin-like 2B
 615
 0.79
chr4_119755136_119755442 0.69 SEC24D
 SEC24 family member D
 2004
 0.43
chr3_27523015_27523166 0.62 SLC4A7
 solute carrier family 4, sodium bicarbonate cotransporter, member 7
 2748
 0.29
chr3_106063956_106064334 0.58 ENSG00000200610
 .
 170599
 0.04
chr2_177001025_177001411 0.55 HOXD3
 homeobox D3
 467
 0.41
chr8_93071638_93071789 0.52 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 3478
 0.37
chr16_4069505_4069681 0.52 RP11-462G12.4
12420
 0.19
chr5_78910199_78910447 0.50 PAPD4
 PAP associated domain containing 4
 1927
 0.42
chr10_17275327_17275794 0.48 RP11-124N14.3
1272
 0.37
chr13_80824234_80824440 0.46 SPRY2
 sprouty homolog 2 (Drosophila)
 89457
 0.1
chr4_5709733_5710324 0.46 EVC2
 Ellis van Creveld syndrome 2
 266
 0.93
chr11_121970307_121971111 0.44 ENSG00000207971
 .
 157
 0.79
chr1_78471558_78472034 0.44 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
 1258
 0.34
chr3_112358713_112358917 0.44 CCDC80
 coiled-coil domain containing 80
 1301
 0.54
chr12_12473193_12473372 0.44 MANSC1
 MANSC domain containing 1
 18326
 0.15
chr15_25123597_25123815 0.43 ENSG00000238615
 .
 15188
 0.12
chr12_100305238_100305389 0.43 ANKS1B
 ankyrin repeat and sterile alpha motif domain containing 1B
 72702
 0.11
chr16_86613931_86614082 0.42 FOXL1
 forkhead box L1
 1891
 0.3
chr14_55077134_55077351 0.42 SAMD4A
 sterile alpha motif domain containing 4A
 42605
 0.17
chr15_99789344_99789838 0.42 TTC23
 tetratricopeptide repeat domain 23
 145
 0.94
chr1_193153819_193153970 0.42 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 1890
 0.36
chr5_10474837_10474988 0.41 RP11-1C1.7
4571
 0.18
chr7_38668604_38668755 0.41 AMPH
 amphiphysin
 2341
 0.39
chr21_36625519_36625670 0.39 RUNX1
 runt-related transcription factor 1
 203953
 0.03
chr2_151467111_151467262 0.39 RND3
 Rho family GTPase 3
 71661
 0.14
chr5_66256594_66256761 0.39 MAST4
 microtubule associated serine/threonine kinase family member 4
 1861
 0.46
chr2_163098757_163099006 0.38 FAP
 fibroblast activation protein, alpha
 677
 0.75
chr5_33890564_33890715 0.38 ADAMTS12
 ADAM metallopeptidase with thrombospondin type 1 motif, 12
 1407
 0.4
chr8_90776220_90776452 0.38 RIPK2
 receptor-interacting serine-threonine kinase 2
 6274
 0.32
chr14_45711437_45711895 0.38 MIS18BP1
 MIS18 binding protein 1
 10714
 0.2
chr7_94026049_94026200 0.38 COL1A2
 collagen, type I, alpha 2
 2251
 0.42
chr11_132813237_132813595 0.37 OPCML
 opioid binding protein/cell adhesion molecule-like
 150
 0.98
chr14_54816467_54816618 0.37 CDKN3
 cyclin-dependent kinase inhibitor 3
 47131
 0.17
chr16_31022230_31022574 0.37 STX1B
 syntaxin 1B
 453
 0.64
chr15_49717369_49717525 0.37 FGF7
 fibroblast growth factor 7
 1990
 0.39
chr14_51242372_51242693 0.37 NIN
 ninein (GSK3B interacting protein)
 9019
 0.17
chr1_51972253_51972404 0.37 RP11-191G24.1
11653
 0.15
chr11_121967218_121967559 0.37 ENSG00000207971
 .
 3164
 0.21
chr13_77403994_77404145 0.36 KCTD12
 potassium channel tetramerization domain containing 12
 56456
 0.13
chr1_240207824_240208231 0.36 FMN2
 formin 2
 30379
 0.22
chr1_231002708_231002859 0.36 C1orf198
 chromosome 1 open reading frame 198
 1616
 0.28
chr15_55881115_55881360 0.36 PYGO1
 pygopus family PHD finger 1
 92
 0.98
chr7_120664009_120664211 0.36 CPED1
 cadherin-like and PC-esterase domain containing 1
 34434
 0.16
chr8_61048624_61048775 0.36 CA8
 carbonic anhydrase VIII
 145272
 0.05
chr1_95388573_95389173 0.35 CNN3
 calponin 3, acidic
 2464
 0.27
chr8_93068476_93068627 0.35 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 6640
 0.32
chr6_103134414_103134565 0.35 GRIK2
 glutamate receptor, ionotropic, kainate 2
 868244
 0.0
chr5_169407172_169407407 0.35 FAM196B
 family with sequence similarity 196, member B
 455
 0.87
chr7_114055343_114055580 0.35 FOXP2
 forkhead box P2
 83
 0.98
chr12_13328389_13328540 0.35 EMP1
 epithelial membrane protein 1
 21186
 0.21
chr8_116674347_116674529 0.35 TRPS1
 trichorhinophalangeal syndrome I
 533
 0.88
chr10_100027009_100027207 0.35 LOXL4
 lysyl oxidase-like 4
 899
 0.63
chr1_29503469_29503620 0.35 SRSF4
 serine/arginine-rich splicing factor 4
 4866
 0.18
chr3_194409728_194410184 0.34 FAM43A
 family with sequence similarity 43, member A
 3334
 0.19
chr7_94024612_94024816 0.34 COL1A2
 collagen, type I, alpha 2
 841
 0.73
chr13_76324065_76324216 0.34 LMO7
 LIM domain 7
 10363
 0.26
chr12_104443529_104443940 0.34 GLT8D2
 glycosyltransferase 8 domain containing 2
 180
 0.94
chr16_22706573_22706828 0.34 ENSG00000265058
 .
 58635
 0.13
chr9_17017802_17018053 0.34 ENSG00000241152
 .
 35972
 0.22
chr17_45352801_45353270 0.34 ENSG00000238419
 .
 16249
 0.13
chr13_98796347_98796640 0.33 FARP1
 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
 759
 0.68
chrX_74966247_74966822 0.33 MAGEE2
 melanoma antigen family E, 2
 38545
 0.23
chr21_28339057_28339347 0.33 ADAMTS5
 ADAM metallopeptidase with thrombospondin type 1 motif, 5
 370
 0.89
chr1_247611615_247612128 0.33 OR2B11
 olfactory receptor, family 2, subfamily B, member 11
 3437
 0.2
chr7_23098334_23098498 0.33 FAM126A
 family with sequence similarity 126, member A
 44667
 0.15
chr2_177022618_177022769 0.33 HOXD3
 homeobox D3
 2926
 0.11
chr10_17151338_17151489 0.33 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 18423
 0.23
chr10_70321971_70322188 0.33 TET1
 tet methylcytosine dioxygenase 1
 1666
 0.36
chr2_225846726_225846877 0.32 ENSG00000263828
 .
 28456
 0.22
chr20_10701589_10701740 0.32 JAG1
 jagged 1
 46970
 0.17
chr1_88150357_88150552 0.32 ENSG00000199318
 .
 231398
 0.02
chr13_74636535_74636686 0.32 KLF12
 Kruppel-like factor 12
 67424
 0.15
chr4_113831338_113831756 0.31 RP11-119H12.6
28061
 0.21
chr3_120168336_120168615 0.31 FSTL1
 follistatin-like 1
 1363
 0.54
chr2_176995490_176995715 0.31 HOXD8
 homeobox D8
 517
 0.55
chr2_227653875_227654026 0.31 IRS1
 insulin receptor substrate 1
 10525
 0.21
chr16_68440497_68440679 0.31 SMPD3
 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
 34427
 0.11
chr16_29230121_29230272 0.31 RP11-231C14.6
93475
 0.05
chr7_18810301_18810537 0.31 ENSG00000222164
 .
 37483
 0.22
chr7_134397415_134397661 0.31 CALD1
 caldesmon 1
 31465
 0.2
chr3_191070684_191070835 0.31 UTS2B
 urotensin 2B
 22434
 0.2
chr11_11485098_11485249 0.31 RP11-483L5.1
106458
 0.06
chrX_34671991_34672311 0.30 TMEM47
 transmembrane protein 47
 3254
 0.41
chr12_66093282_66093481 0.30 HMGA2
 high mobility group AT-hook 2
 124530
 0.05
chr1_92350235_92350616 0.30 TGFBR3
 transforming growth factor, beta receptor III
 1241
 0.52
chr1_205818632_205818989 0.30 PM20D1
 peptidase M20 domain containing 1
 435
 0.83
chr18_55448427_55448643 0.30 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 21792
 0.18
chr4_53411844_53412014 0.30 ENSG00000239068
 .
 35750
 0.18
chr3_29325145_29325351 0.30 RBMS3
 RNA binding motif, single stranded interacting protein 3
 2141
 0.37
chr17_66706567_66706718 0.30 ENSG00000263690
 .
 56058
 0.14
chr2_149574916_149575083 0.30 ENSG00000222126
 .
 8405
 0.24
chr11_121800761_121801203 0.30 ENSG00000252556
 .
 74081
 0.11
chr9_73205228_73205379 0.30 ENSG00000272232
 .
 10926
 0.28
chr8_113763690_113763841 0.29 CSMD3
 CUB and Sushi multiple domains 3
 61494
 0.15
chr5_35130063_35130359 0.29 PRLR
 prolactin receptor
 235
 0.95
chr4_114679710_114679861 0.29 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 2439
 0.44
chr7_90331083_90331234 0.29 CDK14
 cyclin-dependent kinase 14
 7422
 0.29
chr15_48201872_48202023 0.29 SEMA6D
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 143170
 0.04
chr8_13371978_13372169 0.29 DLC1
 deleted in liver cancer 1
 201
 0.95
chr18_24059631_24059830 0.29 KCTD1
 potassium channel tetramerization domain containing 1
 67233
 0.12
chr15_71626398_71626549 0.29 RP11-592N21.2
8190
 0.3
chr12_91721216_91721367 0.29 DCN
 decorin
 144391
 0.05
chr12_118813023_118813174 0.29 SUDS3
 suppressor of defective silencing 3 homolog (S. cerevisiae)
 1087
 0.54
chr6_143014732_143015018 0.29 RP1-67K17.3
54705
 0.17
chr2_181560059_181560213 0.28 ENSG00000264976
 .
 78203
 0.12
chr10_6807939_6808090 0.28 PRKCQ
 protein kinase C, theta
 185751
 0.03
chr2_38977227_38977516 0.28 SRSF7
 serine/arginine-rich splicing factor 7
 665
 0.58
chr3_156396529_156396802 0.28 TIPARP
 TCDD-inducible poly(ADP-ribose) polymerase
 2212
 0.34
chr11_133917712_133918072 0.28 JAM3
 junctional adhesion molecule 3
 20928
 0.21
chr8_105479291_105479486 0.28 DPYS
 dihydropyrimidinase
 107
 0.96
chr10_118608485_118608929 0.28 ENO4
 enolase family member 4
 316
 0.65
chr3_72202008_72202197 0.28 ENSG00000212070
 .
 109477
 0.07
chr5_32442900_32443051 0.28 ZFR
 zinc finger RNA binding protein
 1892
 0.38
chr2_134484670_134484906 0.28 ENSG00000200708
 .
 131126
 0.05
chr2_164734018_164734360 0.28 FIGN
 fidgetin
 141667
 0.05
chr16_21943276_21943517 0.28 RP11-645C24.2
16051
 0.15
chr21_34181326_34181477 0.28 C21orf62
 chromosome 21 open reading frame 62
 1373
 0.37
chr5_123121441_123121770 0.28 CSNK1G3
 casein kinase 1, gamma 3
 197486
 0.03
chr16_73809854_73810059 0.28 PSMD7
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
 520717
 0.0
chr4_48572788_48572939 0.28 ENSG00000251722
 .
 3674
 0.25
chr1_223902537_223902699 0.27 CAPN2
 calpain 2, (m/II) large subunit
 2584
 0.3
chr16_17839007_17839172 0.27 XYLT1
 xylosyltransferase I
 274351
 0.02
chr16_51147416_51147567 0.27 AC009166.5
35659
 0.19
chr5_88081506_88081673 0.27 MEF2C
 myocyte enhancer factor 2C
 38016
 0.18
chr1_236922800_236922951 0.27 ACTN2
 actinin, alpha 2
 28325
 0.2
chrX_46407651_46407802 0.27 ZNF674
 zinc finger protein 674
 2850
 0.28
chr20_62451041_62451439 0.27 ZBTB46
 zinc finger and BTB domain containing 46
 11327
 0.09
chr12_122048138_122048289 0.27 ENSG00000252393
 .
 5406
 0.19
chr1_211749324_211749475 0.27 SLC30A1
 solute carrier family 30 (zinc transporter), member 1
 2685
 0.27
chr10_133793669_133793880 0.27 BNIP3
 BCL2/adenovirus E1B 19kDa interacting protein 3
 1653
 0.46
chr2_111434839_111435049 0.27 BUB1
 BUB1 mitotic checkpoint serine/threonine kinase
 666
 0.76
chr13_80909879_80910030 0.27 SPRY2
 sprouty homolog 2 (Drosophila)
 3840
 0.32
chr19_23258822_23259008 0.27 ZNF730
 zinc finger protein 730
 903
 0.69
chr4_56685755_56685906 0.27 ENSG00000251923
 .
 21028
 0.18
chr20_31273739_31274060 0.27 COMMD7
 COMM domain containing 7
 57313
 0.1
chr10_115141660_115142454 0.27 ENSG00000238380
 .
 28873
 0.24
chr4_183066487_183066672 0.27 AC108142.1
177
 0.77
chr10_131404305_131404456 0.27 AL355531.2
 Uncharacterized protein
 94855
 0.08
chr7_100777700_100777901 0.27 SERPINE1
 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
 7421
 0.1
chr2_156015694_156015845 0.27 ENSG00000223197
 .
 69719
 0.14
chr6_18596391_18596542 0.27 ENSG00000207775
 .
 24451
 0.27
chr1_230358262_230358466 0.26 RP5-956O18.2
45865
 0.16
chr10_63815746_63815944 0.26 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 6875
 0.28
chr16_11444934_11445085 0.26 RP11-485G7.6
1831
 0.18
chr15_80364981_80365385 0.26 ZFAND6
 zinc finger, AN1-type domain 6
 251
 0.94
chr15_96878987_96879612 0.26 ENSG00000222651
 .
 2809
 0.21
chr18_59003210_59003361 0.26 CDH20
 cadherin 20, type 2
 1779
 0.49
chr8_108470289_108470492 0.26 ANGPT1
 angiopoietin 1
 36833
 0.24
chr8_123439435_123439791 0.26 ENSG00000238901
 .
 243917
 0.02
chr8_52809581_52809732 0.26 RP11-110G21.2
722
 0.58
chr8_67445859_67446056 0.26 ENSG00000206949
 .
 32411
 0.15
chr6_11230027_11230357 0.26 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 2699
 0.33
chr18_13725459_13725610 0.26 FAM210A
 family with sequence similarity 210, member A
 1025
 0.35
chr18_59949352_59949799 0.26 RP11-173A16.1
18656
 0.15
chr6_52170291_52170590 0.26 MCM3
 minichromosome maintenance complex component 3
 20805
 0.19
chr8_84428926_84429077 0.26 RALYL
 RALY RNA binding protein-like
 666021
 0.0
chr9_97768076_97768588 0.26 C9orf3
 chromosome 9 open reading frame 3
 1054
 0.55
chr19_37064628_37064871 0.26 AC092295.7
310
 0.66
chr4_17513834_17514187 0.26 QDPR
 quinoid dihydropteridine reductase
 153
 0.95
chr12_21809355_21809506 0.26 LDHB
 lactate dehydrogenase B
 866
 0.6
chr3_170147186_170147337 0.26 CLDN11
 claudin 11
 10406
 0.26
chr21_32931442_32932281 0.25 AP000251.3
303
 0.71
chr12_29734516_29734686 0.25 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
 22556
 0.22
chr2_86332162_86332313 0.25 POLR1A
 polymerase (RNA) I polypeptide A, 194kDa
 1041
 0.34
chr12_80329810_80330005 0.25 PPP1R12A
 protein phosphatase 1, regulatory subunit 12A
 667
 0.6
chr9_90812890_90813286 0.25 ENSG00000252299
 .
 176096
 0.03
chr17_636232_637034 0.25 FAM57A
 family with sequence similarity 57, member A
 268
 0.88
chr21_36256046_36256553 0.25 RUNX1
 runt-related transcription factor 1
 3181
 0.38
chr4_6201946_6202294 0.25 JAKMIP1
 janus kinase and microtubule interacting protein 1
 162
 0.97
chr7_137026886_137027037 0.25 PTN
 pleiotrophin
 1559
 0.52
chr13_32520726_32520877 0.25 EEF1DP3
 eukaryotic translation elongation factor 1 delta pseudogene 3
 5916
 0.29
chr16_4000635_4001034 0.25 RP11-462G12.1
389
 0.84
chr17_15162603_15162754 0.25 RP11-849N15.1
1654
 0.29
chr5_73839584_73839978 0.25 HEXB
 hexosaminidase B (beta polypeptide)
 96067
 0.08
chr22_19511259_19511486 0.25 CLDN5
 claudin 5
 1534
 0.33
chr7_72933105_72933537 0.25 BAZ1B
 bromodomain adjacent to zinc finger domain, 1B
 3281
 0.19
chr7_112759172_112759323 0.25 LINC00998
 long intergenic non-protein coding RNA 998
 579
 0.78
chr12_104880345_104880496 0.25 CHST11
 carbohydrate (chondroitin 4) sulfotransferase 11
 29641
 0.22
chr8_29970332_29970518 0.25 LEPROTL1
 leptin receptor overlapping transcript-like 1
 10969
 0.15
chr17_46651672_46651823 0.25 HOXB3
 homeobox B3
 102
 0.91
chr3_59996849_59997073 0.25 NPCDR1
 nasopharyngeal carcinoma, down-regulated 1
 39378
 0.24
chr4_17812934_17813275 0.25 NCAPG
 non-SMC condensin I complex, subunit G
 579
 0.52
chr2_66808823_66809387 0.25 MEIS1
 Meis homeobox 1
 73046
 0.12
chr5_14446559_14446710 0.25 TRIO
 trio Rho guanine nucleotide exchange factor
 41923
 0.2
chr9_129388558_129388709 0.25 LMX1B
 LIM homeobox transcription factor 1, beta
 11885
 0.16
chr16_53243944_53244222 0.25 CHD9
 chromodomain helicase DNA binding protein 9
 1720
 0.39
chr2_219646650_219647418 0.25 CYP27A1
 cytochrome P450, family 27, subfamily A, polypeptide 1
 555
 0.7
chr8_123701726_123701877 0.25 ENSG00000238901
 .
 18271
 0.25
chr3_175389807_175390608 0.25 ENSG00000201648
 .
 62940
 0.12
chr1_227501319_227501470 0.25 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
 3489
 0.36
chr6_161469926_161470077 0.25 MAP3K4
 mitogen-activated protein kinase kinase kinase 4
 26775
 0.22
chr10_14050350_14050950 0.25 FRMD4A
 FERM domain containing 4A
 118
 0.97
chr4_174103125_174103453 0.24 RP11-10K16.1
12486
 0.18
chr11_85396604_85397203 0.24 CCDC89
 coiled-coil domain containing 89
 417
 0.8
chr18_33737848_33738011 0.24 ELP2
 elongator acetyltransferase complex subunit 2
 28042
 0.14
chr2_225811426_225811868 0.24 DOCK10
 dedicator of cytokinesis 10
 135
 0.98
chr6_113700515_113700666 0.24 ENSG00000222677
 .
 135599
 0.05
chr17_64350080_64350280 0.24 ENSG00000244044
 .
 9967
 0.22
chr1_68667966_68668117 0.24 ENSG00000221203
 .
 18748
 0.2
chr18_55466126_55466277 0.24 ATP8B1
 ATPase, aminophospholipid transporter, class I, type 8B, member 1
 4126
 0.27

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC12_HOXD12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 1.0 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000794)
0.1 0.5 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.3 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.1 0.2 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.2 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.1 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.2 GO:0051608 histamine transport(GO:0051608)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.0 0.2 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.0 0.1 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.1 GO:0000089 mitotic metaphase(GO:0000089)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.0 GO:0090009 primitive streak formation(GO:0090009)
0.0 0.3 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132) metaphase(GO:0051323)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.4 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.4 GO:0043631 RNA polyadenylation(GO:0043631)
0.0 0.0 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0071504 cellular response to heparin(GO:0071504)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.4 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.2 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.0 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.0 0.3 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.1 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.3 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.5 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.4 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.0 GO:0006998 nuclear envelope organization(GO:0006998)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.0 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.0 GO:0001714 endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) regulation of gastrulation(GO:0010470) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.0 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.0 GO:0010755 regulation of plasminogen activation(GO:0010755)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.0 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.0 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.0 GO:0042109 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.4 GO:0090090 negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0 0.2 GO:0009268 response to pH(GO:0009268)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0031058 positive regulation of histone modification(GO:0031058)
0.0 0.1 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:0034405 response to fluid shear stress(GO:0034405)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.2 GO:0006949 syncytium formation(GO:0006949)
0.0 0.0 GO:0018243 protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.0 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.0 GO:0008347 glial cell migration(GO:0008347)
0.0 0.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.0 GO:0010800 regulation of peptidyl-threonine phosphorylation(GO:0010799) positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0071072 regulation of phospholipid biosynthetic process(GO:0071071) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0070076 histone lysine demethylation(GO:0070076)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0045843 negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0 0.0 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.3 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0000796 condensin complex(GO:0000796)
0.1 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.3 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.0 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.3 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.1 0.5 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.1 0.2 GO:0016362 activin receptor activity, type II(GO:0016362)
0.1 0.5 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.1 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.2 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.2 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.3 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.0 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.0 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.0 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0019863 IgE binding(GO:0019863)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)