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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXC13

Z-value: 1.96

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Transcription factors associated with HOXC13

Gene Symbol Gene ID Gene Info
HOXC13
ENSG00000123364.3 homeobox C13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr12_54331845_54331996HOXC136150.4764480.599.2e-02Click!
chr12_54332054_54332205HOXC134060.6388740.383.1e-01Click!
chr12_54329292_54329443HOXC1331680.1126030.333.8e-01Click!

Activity of the HOXC13 motif across conditions

Conditions sorted by the z-value of the HOXC13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_54427392_54427581 1.43 ENSG00000207571
 .
 248
 0.73
chr4_138452878_138453572 1.12 PCDH18
 protocadherin 18
 340
 0.94
chr9_90812890_90813286 1.05 ENSG00000252299
 .
 176096
 0.03
chr3_32010054_32010475 1.05 OSBPL10
 oxysterol binding protein-like 10
 12528
 0.2
chr9_97768076_97768588 0.91 C9orf3
 chromosome 9 open reading frame 3
 1054
 0.55
chr7_15723868_15724269 0.84 MEOX2
 mesenchyme homeobox 2
 2369
 0.37
chr4_138045655_138046009 0.82 ENSG00000222526
 .
 103450
 0.09
chr15_49716260_49716444 0.81 FGF7
 fibroblast growth factor 7
 895
 0.66
chr6_161649839_161650239 0.77 AGPAT4
 1-acylglycerol-3-phosphate O-acyltransferase 4
 45012
 0.2
chr4_114679710_114679861 0.77 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 2439
 0.44
chr15_49717369_49717525 0.74 FGF7
 fibroblast growth factor 7
 1990
 0.39
chr11_121800761_121801203 0.71 ENSG00000252556
 .
 74081
 0.11
chr4_5709733_5710324 0.69 EVC2
 Ellis van Creveld syndrome 2
 266
 0.93
chr2_97593731_97594362 0.69 ENSG00000252845
 .
 28506
 0.12
chr21_38071900_38072434 0.68 SIM2
 single-minded family bHLH transcription factor 2
 176
 0.94
chr12_54367495_54368083 0.68 HOXC11
 homeobox C11
 877
 0.24
chr6_152701966_152702349 0.66 SYNE1-AS1
 SYNE1 antisense RNA 1
 476
 0.79
chr21_17796711_17796936 0.66 ENSG00000207638
 .
 114586
 0.06
chr5_42424322_42424771 0.65 GHR
 growth hormone receptor
 520
 0.88
chr1_95388573_95389173 0.64 CNN3
 calponin 3, acidic
 2464
 0.27
chr15_56207406_56207680 0.63 NEDD4
 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
 309
 0.92
chr3_69494300_69494459 0.63 FRMD4B
 FERM domain containing 4B
 58949
 0.16
chr18_61555576_61555794 0.61 SERPINB2
 serpin peptidase inhibitor, clade B (ovalbumin), member 2
 692
 0.68
chr1_8157048_8157215 0.60 ERRFI1
 ERBB receptor feedback inhibitor 1
 70763
 0.1
chr4_183066487_183066672 0.60 AC108142.1
177
 0.77
chr2_153252119_153252297 0.59 FMNL2
 formin-like 2
 60457
 0.15
chr15_30112674_30113382 0.59 TJP1
 tight junction protein 1
 723
 0.64
chr6_121869435_121869626 0.58 ENSG00000201379
 .
 5758
 0.25
chr3_132316198_132316509 0.58 ACKR4
 atypical chemokine receptor 4
 272
 0.93
chr1_186415843_186415994 0.58 PDC
 phosducin
 281
 0.89
chr21_32715523_32716836 0.58 TIAM1
 T-cell lymphoma invasion and metastasis 1
 415
 0.91
chr2_61898002_61898506 0.57 ENSG00000206973
 .
 65503
 0.12
chr12_84202284_84202435 0.57 ENSG00000221148
 .
 374868
 0.01
chr1_226373050_226373207 0.57 ACBD3
 acyl-CoA binding domain containing 3
 1303
 0.44
chr20_57458298_57458576 0.57 ENSG00000225806
 .
 5410
 0.15
chr8_70180166_70180390 0.57 ENSG00000238808
 .
 157469
 0.04
chr12_50614114_50614771 0.55 RP3-405J10.4
1055
 0.35
chr17_58821066_58821723 0.55 ENSG00000252534
 .
 5013
 0.22
chr2_177001025_177001411 0.55 HOXD3
 homeobox D3
 467
 0.41
chr2_207077565_207077805 0.55 GPR1
 G protein-coupled receptor 1
 410
 0.79
chr6_19837611_19837907 0.55 ID4
 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
 142
 0.95
chr1_92329705_92329906 0.55 TGFBR3
 transforming growth factor, beta receptor III
 2655
 0.31
chr1_115711115_115711431 0.54 TSPAN2
 tetraspanin 2
 79152
 0.1
chr12_104443529_104443940 0.54 GLT8D2
 glycosyltransferase 8 domain containing 2
 180
 0.94
chr2_151335990_151336454 0.53 RND3
 Rho family GTPase 3
 5674
 0.35
chr16_4000635_4001034 0.53 RP11-462G12.1
389
 0.84
chr4_183370400_183371073 0.52 TENM3
 teneurin transmembrane protein 3
 584
 0.84
chr12_91570174_91570436 0.52 DCN
 decorin
 2024
 0.44
chr4_138531037_138531225 0.52 PCDH18
 protocadherin 18
 77483
 0.13
chr22_36233928_36234199 0.52 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 2202
 0.43
chr13_93879365_93880233 0.52 GPC6
 glypican 6
 704
 0.82
chr2_151260036_151260226 0.51 RND3
 Rho family GTPase 3
 81765
 0.12
chr4_157692546_157692809 0.51 RP11-154F14.2
69834
 0.11
chr2_177501805_177501995 0.51 ENSG00000252027
 .
 27504
 0.25
chr8_116669547_116669770 0.51 TRPS1
 trichorhinophalangeal syndrome I
 4247
 0.37
chr7_17030060_17030455 0.51 AGR3
 anterior gradient 3
 108646
 0.07
chr12_54623683_54623971 0.51 ENSG00000265371
 .
 1433
 0.25
chr3_55062710_55062861 0.50 LRTM1
 leucine-rich repeats and transmembrane domains 1
 61670
 0.15
chr15_71184312_71185443 0.50 LRRC49
 leucine rich repeat containing 49
 88
 0.55
chr3_183893852_183894003 0.50 AP2M1
 adaptor-related protein complex 2, mu 1 subunit
 639
 0.55
chr5_92918344_92919004 0.50 NR2F1
 nuclear receptor subfamily 2, group F, member 1
 369
 0.84
chr5_42772787_42772984 0.50 CCDC152
 coiled-coil domain containing 152
 15965
 0.2
chr10_29922441_29923089 0.50 SVIL
 supervillin
 1136
 0.54
chr15_33130691_33130971 0.50 FMN1
 formin 1
 49624
 0.13
chr14_52122113_52122363 0.50 FRMD6
 FERM domain containing 6
 3540
 0.25
chr3_167811230_167811432 0.50 GOLIM4
 golgi integral membrane protein 4
 1801
 0.51
chr2_138721657_138722065 0.49 HNMT
 histamine N-methyltransferase
 19
 0.99
chr2_40591741_40591959 0.49 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 65570
 0.13
chr9_684288_685148 0.48 RP11-130C19.3
837
 0.67
chr3_174157107_174157258 0.48 NAALADL2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 1595
 0.57
chr12_78333571_78333722 0.48 NAV3
 neuron navigator 3
 26410
 0.27
chr2_235861878_235862318 0.48 SH3BP4
 SH3-domain binding protein 4
 1378
 0.62
chr22_24133174_24133325 0.48 SMARCB1
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
 4051
 0.11
chr22_42740354_42740612 0.47 TCF20
 transcription factor 20 (AR1)
 861
 0.66
chr11_125923465_125923616 0.47 CDON
 cell adhesion associated, oncogene regulated
 9166
 0.21
chr2_216297601_216297993 0.47 FN1
 fibronectin 1
 2993
 0.27
chr17_46650833_46651193 0.47 HOXB3
 homeobox B3
 372
 0.67
chr5_98123899_98124050 0.46 RGMB
 repulsive guidance molecule family member b
 14635
 0.21
chr18_53089837_53090372 0.46 TCF4
 transcription factor 4
 361
 0.89
chr13_35962874_35963128 0.46 MAB21L1
 mab-21-like 1 (C. elegans)
 87831
 0.09
chr10_133793669_133793880 0.46 BNIP3
 BCL2/adenovirus E1B 19kDa interacting protein 3
 1653
 0.46
chr15_49750562_49750855 0.46 FGF7
 fibroblast growth factor 7
 35251
 0.19
chr10_35098017_35098428 0.46 PARD3
 par-3 family cell polarity regulator
 6027
 0.24
chr12_95557800_95557974 0.46 FGD6
 FYVE, RhoGEF and PH domain containing 6
 47138
 0.13
chr7_120954228_120954379 0.46 WNT16
 wingless-type MMTV integration site family, member 16
 11118
 0.27
chr2_33359781_33360142 0.45 LTBP1
 latent transforming growth factor beta binding protein 1
 237
 0.96
chr10_97035689_97035840 0.45 PDLIM1
 PDZ and LIM domain 1
 15017
 0.22
chr4_184509430_184509787 0.45 ENSG00000239116
 .
 6154
 0.2
chr16_4069505_4069681 0.45 RP11-462G12.4
12420
 0.19
chr15_96878987_96879612 0.45 ENSG00000222651
 .
 2809
 0.21
chr5_168726900_168727416 0.45 SLIT3
 slit homolog 3 (Drosophila)
 555
 0.83
chr1_164531809_164532055 0.45 PBX1
 pre-B-cell leukemia homeobox 1
 110
 0.98
chr2_120064088_120064263 0.45 STEAP3-AS1
 STEAP3 antisense RNA 1
 57528
 0.1
chr9_78871246_78871464 0.45 PCSK5
 proprotein convertase subtilisin/kexin type 5
 67800
 0.13
chr7_27192241_27192392 0.44 HOXA-AS3
 HOXA cluster antisense RNA 3
 2645
 0.09
chr11_122050649_122050906 0.44 ENSG00000207994
 .
 27761
 0.16
chr7_35460237_35460417 0.44 TBX20
 T-box 20
 166569
 0.04
chr20_17538596_17539086 0.44 BFSP1
 beaded filament structural protein 1, filensin
 642
 0.72
chr2_134484670_134484906 0.44 ENSG00000200708
 .
 131126
 0.05
chr9_89952337_89952906 0.44 ENSG00000212421
 .
 77256
 0.11
chr7_94024612_94024816 0.43 COL1A2
 collagen, type I, alpha 2
 841
 0.73
chr12_54426653_54426823 0.43 HOXC5
 homeobox C5
 101
 0.88
chr1_78961763_78961914 0.43 PTGFR
 prostaglandin F receptor (FP)
 5081
 0.31
chr7_94026049_94026200 0.43 COL1A2
 collagen, type I, alpha 2
 2251
 0.42
chr6_10441253_10441637 0.43 ENSG00000263705
 .
 1495
 0.38
chr18_67714648_67714914 0.43 RTTN
 rotatin
 26827
 0.24
chr12_58283114_58283371 0.43 CTDSP2
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
 42720
 0.08
chr8_58715313_58715521 0.43 FAM110B
 family with sequence similarity 110, member B
 191696
 0.03
chr17_48295929_48296104 0.43 COL1A1
 collagen, type I, alpha 1
 17023
 0.11
chr2_203882992_203883167 0.42 NBEAL1
 neurobeachin-like 1
 3477
 0.29
chr1_72809770_72809921 0.42 NEGR1
 neuronal growth regulator 1
 61428
 0.16
chr9_138361112_138361415 0.42 PPP1R26-AS1
 PPP1R26 antisense RNA 1
 2832
 0.17
chr10_24740047_24740337 0.42 KIAA1217
 KIAA1217
 1830
 0.43
chr3_87034608_87034769 0.42 VGLL3
 vestigial like 3 (Drosophila)
 5164
 0.35
chr11_96040354_96040983 0.42 ENSG00000266192
 .
 33934
 0.17
chr21_40293202_40293353 0.42 ENSG00000272015
 .
 26568
 0.24
chr2_200604849_200605000 0.42 FTCDNL1
 formiminotransferase cyclodeaminase N-terminal like
 110672
 0.07
chr9_4144735_4144971 0.42 GLIS3
 GLIS family zinc finger 3
 340
 0.93
chr6_762027_762197 0.42 EXOC2
 exocyst complex component 2
 68995
 0.13
chr2_190244069_190244254 0.41 WDR75
 WD repeat domain 75
 61998
 0.12
chr14_96722602_96722753 0.41 BDKRB1
 bradykinin receptor B1
 130
 0.94
chr5_52327345_52327496 0.41 CTD-2175A23.1
41312
 0.14
chr21_31599857_31600016 0.41 CLDN8
 claudin 8
 11545
 0.17
chr4_23891941_23892219 0.41 PPARGC1A
 peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
 380
 0.92
chr5_155305875_155306026 0.41 SGCD
 sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
 8596
 0.28
chr17_13498641_13498792 0.41 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 6528
 0.28
chr1_161992740_161992891 0.41 OLFML2B
 olfactomedin-like 2B
 615
 0.79
chr4_148944622_148945028 0.41 RP11-76G10.1
122797
 0.06
chr14_66602242_66602393 0.41 ENSG00000200860
 .
 42036
 0.2
chr4_187643852_187644133 0.41 FAT1
 FAT atypical cadherin 1
 1017
 0.68
chr7_134577069_134577242 0.41 CALD1
 caldesmon 1
 794
 0.75
chr4_111166800_111166966 0.41 ENSG00000212160
 .
 32458
 0.19
chr5_54281245_54281752 0.41 ESM1
 endothelial cell-specific molecule 1
 7
 0.97
chr18_57332365_57332516 0.41 CCBE1
 collagen and calcium binding EGF domains 1
 954
 0.57
chr18_55889348_55889572 0.41 NEDD4L
 neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
 657
 0.77
chr12_78334342_78334902 0.40 NAV3
 neuron navigator 3
 25434
 0.27
chr2_36585229_36585663 0.40 CRIM1
 cysteine rich transmembrane BMP regulator 1 (chordin-like)
 1832
 0.5
chr7_19733441_19733592 0.40 ENSG00000265932
 .
 11543
 0.19
chr18_46520644_46520795 0.40 RP11-15F12.1
29354
 0.17
chr4_187646786_187647042 0.40 FAT1
 FAT atypical cadherin 1
 962
 0.7
chr12_91570586_91570804 0.40 DCN
 decorin
 1634
 0.5
chr12_124774068_124774247 0.40 FAM101A
 family with sequence similarity 101, member A
 447
 0.88
chr2_230309916_230310155 0.40 ENSG00000238782
 .
 160919
 0.04
chr6_155375799_155376279 0.40 TIAM2
 T-cell lymphoma invasion and metastasis 2
 35384
 0.21
chr7_95704908_95705546 0.40 ENSG00000208025
 .
 143841
 0.04
chr12_53044554_53044825 0.40 KRT2
 keratin 2
 1259
 0.32
chr6_126139268_126139437 0.40 NCOA7-AS1
 NCOA7 antisense RNA 1
 652
 0.69
chr8_119120675_119121215 0.40 EXT1
 exostosin glycosyltransferase 1
 1708
 0.54
chr2_202901632_202901854 0.39 FZD7
 frizzled family receptor 7
 2433
 0.27
chr8_42012956_42013246 0.39 AP3M2
 adaptor-related protein complex 3, mu 2 subunit
 967
 0.5
chr2_145212843_145212994 0.39 ZEB2
 zinc finger E-box binding homeobox 2
 24781
 0.24
chr11_101984206_101984357 0.39 YAP1
 Yes-associated protein 1
 1036
 0.49
chrX_99890951_99891409 0.39 TSPAN6
 tetraspanin 6
 623
 0.71
chr12_76242388_76242595 0.39 ENSG00000243420
 .
 109419
 0.06
chr2_176995490_176995715 0.39 HOXD8
 homeobox D8
 517
 0.55
chr8_87188863_87189124 0.39 CTD-3118D11.3
3654
 0.25
chr2_236574591_236575244 0.39 AGAP1
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
 3331
 0.35
chr4_140808325_140808521 0.39 MAML3
 mastermind-like 3 (Drosophila)
 2783
 0.37
chr2_25142056_25142863 0.39 ADCY3
 adenylate cyclase 3
 78
 0.97
chr2_225277050_225277243 0.39 FAM124B
 family with sequence similarity 124B
 10344
 0.29
chr17_807460_807764 0.39 RP11-676J12.7
 Uncharacterized protein
 5260
 0.18
chr7_1407040_1407331 0.39 MICALL2
 MICAL-like 2
 91777
 0.06
chr7_113722711_113723554 0.39 FOXP2
 forkhead box P2
 3483
 0.3
chr13_73438708_73438950 0.39 ENSG00000220981
 .
 13603
 0.19
chr11_121967218_121967559 0.38 ENSG00000207971
 .
 3164
 0.21
chr2_230451733_230451944 0.38 ENSG00000238782
 .
 19116
 0.27
chr21_36256728_36257172 0.38 RUNX1
 runt-related transcription factor 1
 2530
 0.42
chr2_134325837_134326056 0.38 NCKAP5
 NCK-associated protein 5
 85
 0.98
chr10_100069089_100069304 0.38 LOXL4
 lysyl oxidase-like 4
 41189
 0.15
chr6_56707311_56707814 0.38 DST
 dystonin
 381
 0.81
chr3_136677445_136677648 0.38 IL20RB
 interleukin 20 receptor beta
 695
 0.7
chr5_9782917_9783068 0.38 ENSG00000222054
 .
 21973
 0.24
chr15_99789344_99789838 0.38 TTC23
 tetratricopeptide repeat domain 23
 145
 0.94
chr9_14203547_14203816 0.38 NFIB
 nuclear factor I/B
 22884
 0.27
chr6_83073110_83073416 0.38 TPBG
 trophoblast glycoprotein
 85
 0.98
chr4_188524057_188524208 0.38 ZFP42
 ZFP42 zinc finger protein
 392793
 0.01
chr15_25638050_25638201 0.38 UBE3A
 ubiquitin protein ligase E3A
 12528
 0.11
chr18_12315444_12315629 0.37 TUBB6
 tubulin, beta 6 class V
 4570
 0.2
chr10_6780355_6780830 0.37 PRKCQ
 protein kinase C, theta
 158329
 0.04
chr8_30242727_30243445 0.37 RBPMS-AS1
 RBPMS antisense RNA 1
 169
 0.73
chr14_51242372_51242693 0.37 NIN
 ninein (GSK3B interacting protein)
 9019
 0.17
chr5_98112819_98113202 0.37 RGMB
 repulsive guidance molecule family member b
 3671
 0.26
chr10_32236820_32237004 0.37 ARHGAP12
 Rho GTPase activating protein 12
 19170
 0.22
chr6_69346067_69346218 0.37 BAI3
 brain-specific angiogenesis inhibitor 3
 883
 0.52
chr16_56640770_56640921 0.37 MT2A
 metallothionein 2A
 1266
 0.24
chr2_199480864_199481015 0.37 ENSG00000252511
 .
 49486
 0.2
chr10_88730141_88731006 0.37 RP11-96C23.15
10
 0.87
chr4_27219934_27220157 0.37 ENSG00000222206
 .
 5004
 0.36
chr8_98102647_98102881 0.37 KB-1958F4.2
42843
 0.16
chr2_189840807_189841050 0.37 COL3A1
 collagen, type III, alpha 1
 1829
 0.32
chr1_9515825_9515976 0.37 ENSG00000252956
 .
 18063
 0.22
chr3_42094512_42094663 0.37 TRAK1
 trafficking protein, kinesin binding 1
 37975
 0.19
chr8_126667981_126668167 0.37 ENSG00000266452
 .
 211267
 0.02
chr16_23144460_23144740 0.36 USP31
 ubiquitin specific peptidase 31
 15991
 0.22
chr6_8433732_8434221 0.36 SLC35B3
 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
 1740
 0.54
chr4_20253090_20253375 0.36 SLIT2
 slit homolog 2 (Drosophila)
 1651
 0.55
chr3_64338126_64338405 0.36 PRICKLE2
 prickle homolog 2 (Drosophila)
 84610
 0.09
chr8_13369656_13370025 0.36 DLC1
 deleted in liver cancer 1
 2434
 0.32
chr13_93897151_93897349 0.36 GPC6
 glypican 6
 18155
 0.29
chr6_90928649_90929126 0.36 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 77574
 0.1

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.3 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 1.3 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.3 1.2 GO:0043589 skin morphogenesis(GO:0043589)
0.3 0.8 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.3 0.8 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 0.8 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.5 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.2 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.3 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.1 0.4 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.4 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.4 GO:0060013 righting reflex(GO:0060013)
0.1 0.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.6 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.1 GO:0010193 response to ozone(GO:0010193)
0.1 0.3 GO:0001553 luteinization(GO:0001553)
0.1 0.6 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.1 0.6 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.1 0.4 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.2 GO:0022605 oogenesis stage(GO:0022605)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0060435 bronchiole development(GO:0060435)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.2 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 0.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.1 0.5 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 0.2 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.8 GO:0043616 keratinocyte proliferation(GO:0043616)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.8 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.2 GO:0060174 limb bud formation(GO:0060174)
0.1 0.2 GO:0070932 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1 0.1 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1 0.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.1 0.2 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 1.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.1 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 1.2 GO:0042730 fibrinolysis(GO:0042730)
0.1 0.2 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1 0.1 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1 0.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.2 GO:0051608 histamine transport(GO:0051608)
0.1 0.1 GO:0016115 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.2 GO:0060391 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.0 0.0 GO:0090281 negative regulation of calcium ion import(GO:0090281)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:2000189 regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.0 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0 0.1 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0010523 negative regulation of calcium ion transport into cytosol(GO:0010523)
0.0 0.5 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.3 GO:0007143 female meiotic division(GO:0007143)
0.0 0.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.5 GO:0090280 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.7 GO:0014075 response to amine(GO:0014075)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.1 GO:0051531 NFAT protein import into nucleus(GO:0051531) regulation of NFAT protein import into nucleus(GO:0051532)
0.0 0.2 GO:0032906 transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.0 0.5 GO:0060740 prostate gland epithelium morphogenesis(GO:0060740)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.0 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0072033 renal vesicle formation(GO:0072033)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.2 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0061364 regulation of negative chemotaxis(GO:0050923) apoptotic process involved in luteolysis(GO:0061364)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.2 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0006565 L-serine catabolic process(GO:0006565)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0044319 wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.0 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.0 GO:0061037 negative regulation of cartilage development(GO:0061037)
0.0 0.2 GO:0009886 post-embryonic morphogenesis(GO:0009886)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.1 GO:0042424 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.0 GO:0060850 regulation of transcription involved in cell fate commitment(GO:0060850)
0.0 0.0 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.3 GO:0098856 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0042417 dopamine metabolic process(GO:0042417)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.1 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.2 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0071548 response to dexamethasone(GO:0071548)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0060192 negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.0 GO:0090192 glomerular mesangial cell proliferation(GO:0072110) regulation of glomerular mesangial cell proliferation(GO:0072124) regulation of glomerulus development(GO:0090192)
0.0 0.1 GO:0043501 skeletal muscle adaptation(GO:0043501)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.0 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.0 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0002011 morphogenesis of an epithelial sheet(GO:0002011)
0.0 0.1 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.6 GO:0007602 phototransduction(GO:0007602)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.0 GO:0034114 heterotypic cell-cell adhesion(GO:0034113) regulation of heterotypic cell-cell adhesion(GO:0034114)
0.0 0.0 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.0 GO:0042363 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:1901890 positive regulation of focal adhesion assembly(GO:0051894) positive regulation of cell junction assembly(GO:1901890) positive regulation of adherens junction organization(GO:1903393)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.0 GO:0045117 azole transport(GO:0045117)
0.0 0.2 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.3 GO:0007492 endoderm development(GO:0007492)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:1903318 negative regulation of protein processing(GO:0010955) negative regulation of protein maturation(GO:1903318)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.0 GO:0043558 regulation of translational initiation in response to stress(GO:0043558)
0.0 0.0 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.0 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0071384 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.3 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.4 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.0 GO:0032222 regulation of synaptic transmission, cholinergic(GO:0032222)
0.0 0.2 GO:0048814 regulation of dendrite morphogenesis(GO:0048814)
0.0 0.1 GO:0051818 disruption of cells of other organism involved in symbiotic interaction(GO:0051818) killing of cells in other organism involved in symbiotic interaction(GO:0051883)
0.0 0.0 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0060976 coronary vasculature development(GO:0060976)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.0 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.0 GO:0034243 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.5 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0006693 prostaglandin metabolic process(GO:0006693)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.2 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.0 0.0 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.0 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:0060693 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.1 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0042698 ovulation cycle(GO:0042698)
0.0 0.0 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.0 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.0 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0071437 invadopodium(GO:0071437)
0.1 0.6 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0001527 microfibril(GO:0001527)
0.0 0.3 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0043256 laminin complex(GO:0043256)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.4 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0002141 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.0 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 4.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 1.1 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 1.3 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.0 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.4 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0032156 septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.0 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.5 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.2 0.7 GO:0048495 Roundabout binding(GO:0048495)
0.2 0.6 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.2 0.6 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.2 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.7 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0048185 activin binding(GO:0048185)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.2 GO:0005113 patched binding(GO:0005113)
0.1 0.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0030507 spectrin binding(GO:0030507)
0.1 0.1 GO:0045545 syndecan binding(GO:0045545)
0.1 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.6 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.7 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 1.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.1 GO:0034648 histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.0 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 4.8 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.1 GO:0043176 amine binding(GO:0043176)
0.0 0.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0008504 monoamine transmembrane transporter activity(GO:0008504)
0.0 0.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0030332 cyclin binding(GO:0030332)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.0 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 1.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 1.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.6 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.7 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.0 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.0 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.2 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis