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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HOXC6_HOXA7

Z-value: 0.64

Motif logo

Transcription factors associated with HOXC6_HOXA7

Gene Symbol	Gene ID	Gene Info
HOXC6 Ensembl NCBI GeneCards UniProt	ENSG00000197757.7	HOXC6
HOXA7 Ensembl NCBI GeneCards UniProt	ENSG00000122592.6	HOXA7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
HOXA7	chr7_27199352_27199503	1872	0.117379	-0.76	1.9e-02	Click!
HOXA7	chr7_27197659_27197810	179	0.830311	-0.51	1.6e-01	Click!
HOXA7	chr7_27198059_27198210	579	0.443014	-0.48	1.9e-01	Click!
HOXA7	chr7_27196933_27197228	475	0.528812	-0.47	2.0e-01	Click!
HOXA7	chr7_27198968_27199186	1522	0.146054	-0.44	2.4e-01	Click!
HOXC6	chr12_54406961_54407131	2635	0.091558	0.61	8.4e-02	Click!
HOXC6	chr12_54420892_54421043	1175	0.224136	0.47	2.0e-01	Click!
HOXC6	chr12_54408009_54408173	1590	0.143819	0.46	2.1e-01	Click!
HOXC6	chr12_54408811_54408962	795	0.316110	0.45	2.2e-01	Click!
HOXC6	chr12_54384773_54384996	476	0.404093	0.44	2.4e-01	Click!

Activity of the HOXC6_HOXA7 motif across conditions

Conditions sorted by the z-value of the HOXC6_HOXA7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_22968352_22968523	0.46	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	12266	0.1
chrX_19815653_19816006	0.40	SH3KBP1	SH3-domain kinase binding protein 1	2040	0.46
chr5_81762775_81762926	0.39	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	161684	0.04
chr14_22947593_22947744	0.39	TRAJ60	T cell receptor alpha joining 60 (pseudogene)	2372	0.15
chr3_124303613_124304383	0.38	KALRN	kalirin, RhoGEF kinase	329	0.93
chr19_50062782_50062933	0.37	NOSIP	nitric oxide synthase interacting protein	1030	0.27
chr18_56106091_56106384	0.37	ENSG00000207778	.	12069	0.17
chr5_66646304_66646752	0.34	ENSG00000222939	.	113908	0.07
chr10_47640402_47640757	0.33	ANTXRLP1	anthrax toxin receptor-like pseudogene 1	4212	0.25
chr5_35863316_35863652	0.32	IL7R	interleukin 7 receptor	6490	0.21
chr20_53217986_53218137	0.32	DOK5	docking protein 5	125804	0.06
chr6_116834038_116834189	0.31	TRAPPC3L	trafficking protein particle complex 3-like	607	0.55
chr15_26095105_26095679	0.31	ENSG00000266517	.	1420	0.42
chr12_27472599_27472750	0.31	ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2	13113	0.22
chr4_82327183_82327334	0.31	RASGEF1B	RasGEF domain family, member 1B	65132	0.13
chr5_119523820_119523971	0.30	ENSG00000251975	.	149453	0.05
chr12_47611625_47611801	0.30	PCED1B	PC-esterase domain containing 1B	1332	0.49
chr3_114136122_114136315	0.30	ZBTB20-AS1	ZBTB20 antisense RNA 1	29702	0.18
chr7_28429769_28429920	0.30	CREB5	cAMP responsive element binding protein 5	19162	0.28
chr5_44684027_44684178	0.30	ENSG00000263556	.	32190	0.23
chr17_47766049_47766200	0.29	SPOP	speckle-type POZ protein	10528	0.14
chr2_175710954_175711206	0.29	CHN1	chimerin 1	53	0.98
chr6_145693454_145693782	0.29	ENSG00000221796	.	23724	0.26
chr12_29696081_29696326	0.29	RP11-310I24.1		23539	0.2
chr14_22985583_22985743	0.29	TRAJ15	T cell receptor alpha joining 15	12917	0.1
chr3_36504651_36504802	0.29	STAC	SH3 and cysteine rich domain	82661	0.11
chr17_37774592_37774840	0.29	PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	8277	0.12
chr4_2486639_2486842	0.28	RNF4	ring finger protein 4	4798	0.2
chr1_89594453_89594640	0.28	GBP2	guanylate binding protein 2, interferon-inducible	2749	0.27
chr3_186745077_186745229	0.28	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1	1882	0.42
chr14_98603340_98603491	0.28	C14orf64	chromosome 14 open reading frame 64	158954	0.04
chr12_7985471_7986071	0.27	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	359	0.8
chr2_38894094_38894271	0.27	GALM	galactose mutarotase (aldose 1-epimerase)	923	0.55
chr8_126960676_126960849	0.26	ENSG00000206695	.	47567	0.2
chr9_95730621_95730837	0.26	FGD3	FYVE, RhoGEF and PH domain containing 3	4486	0.25
chr14_65450405_65450576	0.26	FNTB	farnesyltransferase, CAAX box, beta	2948	0.17
chr11_88087417_88087693	0.25	CTSC	cathepsin C	16600	0.28
chrX_135732358_135732618	0.25	CD40LG	CD40 ligand	2102	0.29
chr5_140457403_140457554	0.25	PCDHB2	protocadherin beta 2	16749	0.09
chr6_56715487_56715638	0.25	DST	dystonin	1187	0.53
chr7_15340100_15340251	0.24	AGMO	alkylglycerol monooxygenase	65637	0.15
chr14_100535454_100535614	0.24	EVL	Enah/Vasp-like	2760	0.21
chr16_86638626_86639076	0.24	FOXL1	forkhead box L1	26736	0.16
chr12_12658847_12659363	0.24	DUSP16	dual specificity phosphatase 16	14954	0.24
chr5_154033985_154034136	0.24	ENSG00000221552	.	31276	0.14
chr3_194409728_194410184	0.24	FAM43A	family with sequence similarity 43, member A	3334	0.19
chr14_68774448_68774599	0.24	ENSG00000243546	.	71267	0.11
chr10_6627562_6627792	0.24	PRKCQ	protein kinase C, theta	5414	0.34
chr15_58702506_58703018	0.24	LIPC	lipase, hepatic	6	0.98
chr7_110732102_110732377	0.23	LRRN3	leucine rich repeat neuronal 3	1140	0.59
chr5_67576888_67577103	0.23	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	860	0.74
chr3_98619475_98619750	0.23	DCBLD2	discoidin, CUB and LCCL domain containing 2	403	0.8
chr13_45272325_45272476	0.23	ENSG00000238932	.	69591	0.12
chr1_109751420_109751576	0.23	ENSG00000238310	.	1028	0.46
chr6_11394166_11394363	0.23	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	11683	0.27
chr6_21004300_21004557	0.23	ENSG00000252046	.	10629	0.32
chr10_17707589_17707769	0.23	ENSG00000251959	.	13508	0.15
chr5_174487191_174487429	0.22	ENSG00000266890	.	308573	0.01
chr20_18446613_18446764	0.22	DZANK1	double zinc ribbon and ankyrin repeat domains 1	663	0.48
chr1_20649271_20649434	0.22	RP4-745E8.2		328	0.9
chr3_143445457_143445608	0.22	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	121768	0.06
chr1_193152081_193152232	0.22	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	3628	0.25
chrY_15815919_15816489	0.22	TMSB4Y	thymosin beta 4, Y-linked	757	0.72
chr15_40112127_40112278	0.22	RP11-37C7.2		4572	0.19
chr16_12282412_12282563	0.22	SNX29	sorting nexin 29	58933	0.11
chr15_70867504_70867655	0.22	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	127041	0.06
chr9_123686452_123686718	0.22	TRAF1	TNF receptor-associated factor 1	4462	0.25
chr14_57274863_57275150	0.21	OTX2	orthodenticle homeobox 2	2160	0.26
chr3_189766902_189767149	0.21	ENSG00000265045	.	64698	0.1
chr16_4162545_4162832	0.21	ADCY9	adenylate cyclase 9	1339	0.51
chr22_34248307_34248458	0.21	LARGE	like-glycosyltransferase	9230	0.27
chr18_32626039_32626502	0.21	MAPRE2	microtubule-associated protein, RP/EB family, member 2	4656	0.33
chr7_15722890_15723041	0.21	MEOX2	mesenchyme homeobox 2	3472	0.3
chr1_245551646_245551892	0.21	ENSG00000221165	.	18133	0.26
chr17_21935353_21935504	0.21	MTRNR2L1	MT-RNR2-like 1	87009	0.09
chr5_60704297_60704575	0.21	ZSWIM6	zinc finger, SWIM-type containing 6	76336	0.11
chr10_17151338_17151489	0.21	CUBN	cubilin (intrinsic factor-cobalamin receptor)	18423	0.23
chr17_66700653_66700804	0.21	ENSG00000263690	.	61972	0.13
chr6_16135670_16135821	0.21	ENSG00000263712	.	6042	0.19
chr3_108549304_108549455	0.21	TRAT1	T cell receptor associated transmembrane adaptor 1	7760	0.27
chr14_62170526_62170677	0.20	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	6261	0.26
chr4_157594550_157594701	0.20	RP11-171N4.3		30893	0.2
chr4_1514296_1514447	0.20	NKX1-1	NK1 homeobox 1	114252	0.05
chr10_33241565_33241796	0.20	ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	2911	0.37
chr6_16420893_16421044	0.20	ENSG00000265642	.	7786	0.31
chr9_98188423_98189086	0.20	PTCH1	patched 1	54013	0.12
chr9_88206707_88206867	0.20	AGTPBP1	ATP/GTP binding protein 1	89414	0.1
chr8_13346130_13346281	0.20	DLC1	deleted in liver cancer 1	10545	0.24
chr12_111016409_111016682	0.19	PPTC7	PTC7 protein phosphatase homolog (S. cerevisiae)	4580	0.18
chr1_172109378_172109611	0.19	ENSG00000207949	.	1447	0.39
chr10_63813819_63813970	0.19	ARID5B	AT rich interactive domain 5B (MRF1-like)	4924	0.3
chr2_133058367_133058560	0.19	ENSG00000221288	.	43810	0.15
chr1_227501319_227501470	0.19	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	3489	0.36
chr5_125036350_125036501	0.19	ENSG00000222107	.	349601	0.01
chr13_24146066_24146217	0.19	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1338	0.59
chr10_28336370_28336521	0.19	ARMC4	armadillo repeat containing 4	48468	0.18
chr7_24768620_24768771	0.19	DFNA5	deafness, autosomal dominant 5	9980	0.29
chr7_28002200_28002423	0.19	JAZF1	JAZF zinc finger 1	29364	0.22
chr5_39186752_39186903	0.19	FYB	FYN binding protein	16302	0.26
chr1_158903283_158903483	0.19	PYHIN1	pyrin and HIN domain family, member 1	2025	0.36
chr5_67580506_67580669	0.19	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	3609	0.36
chr12_92534627_92535592	0.19	C12orf79	chromosome 12 open reading frame 79	1335	0.39
chrX_57618068_57618312	0.19	ZXDB	zinc finger, X-linked, duplicated B	79	0.99
chr10_29908483_29908634	0.19	SVIL	supervillin	15343	0.18
chrX_72782625_72782944	0.18	CHIC1	cysteine-rich hydrophobic domain 1	252	0.96
chr11_108040783_108041103	0.18	NPAT	nuclear protein, ataxia-telangiectasia locus	8051	0.17
chr14_29254002_29254283	0.18	RP11-966I7.2		851	0.56
chr2_25500266_25500584	0.18	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	25245	0.19
chr14_71454929_71455080	0.18	PCNX	pecanex homolog (Drosophila)	24744	0.26
chr12_866633_866784	0.18	WNK1	WNK lysine deficient protein kinase 1	3976	0.25
chr21_35306376_35306527	0.18	LINC00649	long intergenic non-protein coding RNA 649	2933	0.21
chr4_169564516_169564687	0.18	RP11-610J23.1		5137	0.22
chr7_39170814_39170965	0.18	POU6F2	POU class 6 homeobox 2	45428	0.18
chr2_225809390_225809894	0.18	DOCK10	dedicator of cytokinesis 10	2140	0.45
chr8_77592906_77593199	0.18	ZFHX4	zinc finger homeobox 4	402	0.86
chr9_124921339_124921603	0.18	NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	595	0.48
chr3_105295301_105295452	0.18	ALCAM	activated leukocyte cell adhesion molecule	42930	0.21
chrX_57022329_57022623	0.18	SPIN3	spindlin family, member 3	507	0.84
chr15_60883034_60883482	0.18	RORA	RAR-related orphan receptor A	1482	0.47
chr1_85247835_85247986	0.18	ENSG00000251899	.	10972	0.25
chr8_95973021_95973268	0.18	NDUFAF6	NADH dehydrogenase (ubiquinone) complex I, assembly factor 6	2908	0.2
chr15_58920533_58921016	0.18	ENSG00000239100	.	28340	0.16
chr18_34914843_34915294	0.18	RP11-797E24.3		60645	0.13
chr17_1992653_1992959	0.18	RP11-667K14.5		169	0.91
chr1_51447205_51447356	0.18	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	11664	0.2
chr8_91554264_91554415	0.18	ENSG00000199354	.	30983	0.2
chr13_39610123_39610274	0.18	PROSER1	proline and serine rich 1	1776	0.34
chr3_56949638_56949992	0.18	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	684	0.75
chr13_99953854_99954138	0.18	GPR183	G protein-coupled receptor 183	5663	0.22
chr9_18296716_18296867	0.17	ADAMTSL1	ADAMTS-like 1	177101	0.03
chr10_51500864_51501147	0.17	AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	14678	0.19
chr7_106822662_106822813	0.17	HBP1	HMG-box transcription factor 1	2374	0.31
chr1_57041430_57041821	0.17	PPAP2B	phosphatidic acid phosphatase type 2B	3616	0.34
chr2_183289734_183289997	0.17	PDE1A	phosphodiesterase 1A, calmodulin-dependent	1884	0.49
chr6_26198173_26198564	0.17	HIST1H3D	histone cluster 1, H3d	890	0.22
chr1_111212431_111212582	0.17	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	5149	0.2
chr9_20041214_20041376	0.17	ENSG00000266224	.	211544	0.02
chr3_170136599_170137401	0.17	CLDN11	claudin 11	145	0.97
chr3_40518130_40518400	0.17	ZNF619	zinc finger protein 619	339	0.84
chr11_96197527_96197689	0.17	ENSG00000200411	.	10248	0.25
chr16_1584614_1584961	0.17	TMEM204	transmembrane protein 204	1213	0.24
chr8_90845937_90846088	0.17	ENSG00000207359	.	67040	0.11
chr15_38848503_38848654	0.17	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	3705	0.23
chr15_50156073_50156224	0.17	ATP8B4	ATPase, class I, type 8B, member 4	12744	0.22
chr8_80739322_80739697	0.17	ENSG00000238884	.	27079	0.22
chr8_94931050_94931201	0.17	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	13	0.98
chr5_58883529_58883730	0.17	PDE4D	phosphodiesterase 4D, cAMP-specific	1304	0.62
chrX_114924538_114924731	0.17	ENSG00000264759	.	13498	0.18
chr10_114291692_114291843	0.17	VTI1A	vesicle transport through interaction with t-SNAREs 1A	84751	0.08
chr2_177021858_177022419	0.16	HOXD3	homeobox D3	3481	0.1
chr6_127125664_127125831	0.16	ENSG00000201613	.	214208	0.02
chr4_100009284_100009464	0.16	ADH5	alcohol dehydrogenase 5 (class III), chi polypeptide	528	0.5
chr3_63338970_63339121	0.16	ENSG00000252662	.	18582	0.26
chr6_43019642_43019793	0.16	CUL7	cullin 7	1720	0.17
chrX_28607014_28607165	0.16	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	1573	0.57
chr17_78705219_78705370	0.16	RP11-28G8.1		74138	0.1
chr8_38323279_38323475	0.16	FGFR1	fibroblast growth factor receptor 1	804	0.6
chr12_92532725_92532888	0.16	C12orf79	chromosome 12 open reading frame 79	2009	0.29
chr4_175041157_175041343	0.16	FBXO8	F-box protein 8	163564	0.04
chr3_114801119_114801270	0.16	ZBTB20	zinc finger and BTB domain containing 20	10972	0.32
chr14_30663660_30663811	0.16	PRKD1	protein kinase D1	2631	0.43
chr4_135385341_135385492	0.16	PABPC4L	poly(A) binding protein, cytoplasmic 4-like	262513	0.02
chr20_8841205_8841356	0.16	ENSG00000201348	.	29447	0.23
chr18_9117636_9118003	0.16	RP11-143J12.3		1944	0.28
chr4_107773590_107773741	0.16	DKK2	dickkopf WNT signaling pathway inhibitor 2	183789	0.03
chr13_47253658_47254162	0.16	LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	61	0.99
chr8_51255795_51255946	0.16	RP11-759A9.1		37705	0.2
chr1_111212136_111212287	0.16	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	5444	0.2
chr11_111794495_111794677	0.16	CRYAB	crystallin, alpha B	140	0.91
chr1_205717316_205717519	0.16	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	1987	0.26
chr22_31317515_31317990	0.16	MORC2-AS1	MORC2 antisense RNA 1	543	0.73
chr14_53575940_53576287	0.16	DDHD1	DDHD domain containing 1	40691	0.14
chr11_128559988_128560195	0.16	FLI1	Fli-1 proto-oncogene, ETS transcription factor	2298	0.26
chr7_122115813_122115964	0.16	CADPS2	Ca++-dependent secretion activator 2	37458	0.19
chr14_50862384_50862648	0.16	CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	101	0.97
chr22_50318944_50319095	0.16	CRELD2	cysteine-rich with EGF-like domains 2	6638	0.17
chr3_73606637_73606788	0.16	PDZRN3	PDZ domain containing ring finger 3	4057	0.29
chr21_39807445_39807798	0.16	ERG	v-ets avian erythroblastosis virus E26 oncogene homolog	62724	0.14
chr10_63999686_63999837	0.16	RTKN2	rhotekin 2	3739	0.34
chr2_204572133_204572358	0.16	CD28	CD28 molecule	829	0.71
chr7_94025506_94025990	0.16	COL1A2	collagen, type I, alpha 2	1875	0.46
chr14_52778615_52778779	0.16	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	2326	0.38
chr10_123733699_123733904	0.15	NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	472	0.82
chr6_154691911_154692077	0.15	IPCEF1	interaction protein for cytohesin exchange factors 1	14068	0.27
chr6_143501955_143502106	0.15	AIG1	androgen-induced 1	54643	0.14
chr1_10341352_10341503	0.15	ENSG00000199562	.	17597	0.15
chr12_14520726_14520877	0.15	ATF7IP	activating transcription factor 7 interacting protein	494	0.85
chr14_71933799_71933950	0.15	ENSG00000242330	.	18468	0.23
chrX_53356672_53356823	0.15	ENSG00000207408	.	2980	0.23
chr8_101731752_101732025	0.15	PABPC1	poly(A) binding protein, cytoplasmic 1	1770	0.27
chr4_39032194_39032374	0.15	TMEM156	transmembrane protein 156	1757	0.38
chr8_135790318_135790469	0.15	ENSG00000207582	.	22457	0.21
chr15_44120227_44120469	0.15	WDR76	WD repeat domain 76	1162	0.29
chr7_18794250_18794418	0.15	ENSG00000222164	.	53568	0.17
chr2_197662576_197662727	0.15	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	1732	0.37
chr3_12436703_12437398	0.15	PPARG	peroxisome proliferator-activated receptor gamma	44079	0.15
chr2_155000932_155001083	0.15	ENSG00000266512	.	1713	0.51
chr3_95425254_95425405	0.15	ENSG00000221477	.	460417	0.01
chr3_121964996_121965193	0.15	ENSG00000252170	.	481	0.79
chr3_135284920_135285071	0.15	ENSG00000253004	.	233627	0.02

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.5	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.2	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.2	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.0	0.2	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.0	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0070933	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0070601	centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0	0.1	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.1	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.1	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0045601	regulation of endothelial cell differentiation(GO:0045601)
0.0	0.2	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0	0.1	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.1	GO:1903521	apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0	0.1	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0072007	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0	0.1	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.1	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	0.1	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.1	GO:0002335	mature B cell differentiation(GO:0002335)
0.0	0.0	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.2	GO:0010510	acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.0	GO:0009151	purine deoxyribonucleotide metabolic process(GO:0009151)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.0	GO:0051451	myoblast migration(GO:0051451)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.1	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0072203	cell proliferation involved in metanephros development(GO:0072203)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.0	GO:0008049	male courtship behavior(GO:0008049)
0.0	0.0	GO:0034085	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.0	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.0	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.1	GO:0051503	adenine nucleotide transport(GO:0051503)
0.0	0.1	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0	0.2	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.0	0.1	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	0.0	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.3	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.0	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:1901984	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.0	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.0	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.0	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.1	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.1	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.0	GO:1900078	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.0	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.0	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0	0.0	GO:0048867	stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0	0.0	GO:0042362	fat-soluble vitamin biosynthetic process(GO:0042362)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.0	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0014874	response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0	0.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.0	GO:0014850	response to muscle activity(GO:0014850)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0030056	hemidesmosome(GO:0030056)
0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	GO:0072487	MSL complex(GO:0072487)
0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.4	GO:0031594	neuromuscular junction(GO:0031594)
0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	GO:0031094	platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.0	GO:0030312	external encapsulating structure(GO:0030312)
0.1	GO:0034451	centriolar satellite(GO:0034451)
0.1	GO:0008091	spectrin(GO:0008091)
0.0	GO:0031931	TORC1 complex(GO:0031931)
0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	GO:0005787	signal peptidase complex(GO:0005787)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.1	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.2	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.3	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.0	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.0	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0030276	clathrin binding(GO:0030276)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0030507	spectrin binding(GO:0030507)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.2	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0016778	diphosphotransferase activity(GO:0016778)
0.0	0.1	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.1	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.4	PID CD40 PATHWAY	CD40/CD40L signaling
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.2	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.0	0.1	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.0	REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM	Genes involved in Transport of Mature Transcript to Cytoplasm
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.6	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane