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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for HOXC6_HOXA7

Z-value: 0.64

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Transcription factors associated with HOXC6_HOXA7

Gene Symbol Gene ID Gene Info
HOXC6
ENSG00000197757.7 homeobox C6
HOXA7
ENSG00000122592.6 homeobox A7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr7_27199352_27199503HOXA718720.117379-0.761.9e-02Click!
chr7_27197659_27197810HOXA71790.830311-0.511.6e-01Click!
chr7_27198059_27198210HOXA75790.443014-0.481.9e-01Click!
chr7_27196933_27197228HOXA74750.528812-0.472.0e-01Click!
chr7_27198968_27199186HOXA715220.146054-0.442.4e-01Click!
chr12_54406961_54407131HOXC626350.0915580.618.4e-02Click!
chr12_54420892_54421043HOXC611750.2241360.472.0e-01Click!
chr12_54408009_54408173HOXC615900.1438190.462.1e-01Click!
chr12_54408811_54408962HOXC67950.3161100.452.2e-01Click!
chr12_54384773_54384996HOXC64760.4040930.442.4e-01Click!

Activity of the HOXC6_HOXA7 motif across conditions

Conditions sorted by the z-value of the HOXC6_HOXA7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr14_22968352_22968523 0.46 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 12266
 0.1
chrX_19815653_19816006 0.40 SH3KBP1
 SH3-domain kinase binding protein 1
 2040
 0.46
chr5_81762775_81762926 0.39 ATP6AP1L
 ATPase, H+ transporting, lysosomal accessory protein 1-like
 161684
 0.04
chr14_22947593_22947744 0.39 TRAJ60
 T cell receptor alpha joining 60 (pseudogene)
 2372
 0.15
chr3_124303613_124304383 0.38 KALRN
 kalirin, RhoGEF kinase
 329
 0.93
chr19_50062782_50062933 0.37 NOSIP
 nitric oxide synthase interacting protein
 1030
 0.27
chr18_56106091_56106384 0.37 ENSG00000207778
 .
 12069
 0.17
chr5_66646304_66646752 0.34 ENSG00000222939
 .
 113908
 0.07
chr10_47640402_47640757 0.33 ANTXRLP1
 anthrax toxin receptor-like pseudogene 1
 4212
 0.25
chr5_35863316_35863652 0.32 IL7R
 interleukin 7 receptor
 6490
 0.21
chr20_53217986_53218137 0.32 DOK5
 docking protein 5
 125804
 0.06
chr6_116834038_116834189 0.31 TRAPPC3L
 trafficking protein particle complex 3-like
 607
 0.55
chr15_26095105_26095679 0.31 ENSG00000266517
 .
 1420
 0.42
chr12_27472599_27472750 0.31 ARNTL2
 aryl hydrocarbon receptor nuclear translocator-like 2
 13113
 0.22
chr4_82327183_82327334 0.31 RASGEF1B
 RasGEF domain family, member 1B
 65132
 0.13
chr5_119523820_119523971 0.30 ENSG00000251975
 .
 149453
 0.05
chr12_47611625_47611801 0.30 PCED1B
 PC-esterase domain containing 1B
 1332
 0.49
chr3_114136122_114136315 0.30 ZBTB20-AS1
 ZBTB20 antisense RNA 1
 29702
 0.18
chr7_28429769_28429920 0.30 CREB5
 cAMP responsive element binding protein 5
 19162
 0.28
chr5_44684027_44684178 0.30 ENSG00000263556
 .
 32190
 0.23
chr17_47766049_47766200 0.29 SPOP
 speckle-type POZ protein
 10528
 0.14
chr2_175710954_175711206 0.29 CHN1
 chimerin 1
 53
 0.98
chr6_145693454_145693782 0.29 ENSG00000221796
 .
 23724
 0.26
chr12_29696081_29696326 0.29 RP11-310I24.1
23539
 0.2
chr14_22985583_22985743 0.29 TRAJ15
 T cell receptor alpha joining 15
 12917
 0.1
chr3_36504651_36504802 0.29 STAC
 SH3 and cysteine rich domain
 82661
 0.11
chr17_37774592_37774840 0.29 PPP1R1B
 protein phosphatase 1, regulatory (inhibitor) subunit 1B
 8277
 0.12
chr4_2486639_2486842 0.28 RNF4
 ring finger protein 4
 4798
 0.2
chr1_89594453_89594640 0.28 GBP2
 guanylate binding protein 2, interferon-inducible
 2749
 0.27
chr3_186745077_186745229 0.28 ST6GAL1
 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
 1882
 0.42
chr14_98603340_98603491 0.28 C14orf64
 chromosome 14 open reading frame 64
 158954
 0.04
chr12_7985471_7986071 0.27 SLC2A14
 solute carrier family 2 (facilitated glucose transporter), member 14
 359
 0.8
chr2_38894094_38894271 0.27 GALM
 galactose mutarotase (aldose 1-epimerase)
 923
 0.55
chr8_126960676_126960849 0.26 ENSG00000206695
 .
 47567
 0.2
chr9_95730621_95730837 0.26 FGD3
 FYVE, RhoGEF and PH domain containing 3
 4486
 0.25
chr14_65450405_65450576 0.26 FNTB
 farnesyltransferase, CAAX box, beta
 2948
 0.17
chr11_88087417_88087693 0.25 CTSC
 cathepsin C
 16600
 0.28
chrX_135732358_135732618 0.25 CD40LG
 CD40 ligand
 2102
 0.29
chr5_140457403_140457554 0.25 PCDHB2
 protocadherin beta 2
 16749
 0.09
chr6_56715487_56715638 0.25 DST
 dystonin
 1187
 0.53
chr7_15340100_15340251 0.24 AGMO
 alkylglycerol monooxygenase
 65637
 0.15
chr14_100535454_100535614 0.24 EVL
 Enah/Vasp-like
 2760
 0.21
chr16_86638626_86639076 0.24 FOXL1
 forkhead box L1
 26736
 0.16
chr12_12658847_12659363 0.24 DUSP16
 dual specificity phosphatase 16
 14954
 0.24
chr5_154033985_154034136 0.24 ENSG00000221552
 .
 31276
 0.14
chr3_194409728_194410184 0.24 FAM43A
 family with sequence similarity 43, member A
 3334
 0.19
chr14_68774448_68774599 0.24 ENSG00000243546
 .
 71267
 0.11
chr10_6627562_6627792 0.24 PRKCQ
 protein kinase C, theta
 5414
 0.34
chr15_58702506_58703018 0.24 LIPC
 lipase, hepatic
 6
 0.98
chr7_110732102_110732377 0.23 LRRN3
 leucine rich repeat neuronal 3
 1140
 0.59
chr5_67576888_67577103 0.23 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 860
 0.74
chr3_98619475_98619750 0.23 DCBLD2
 discoidin, CUB and LCCL domain containing 2
 403
 0.8
chr13_45272325_45272476 0.23 ENSG00000238932
 .
 69591
 0.12
chr1_109751420_109751576 0.23 ENSG00000238310
 .
 1028
 0.46
chr6_11394166_11394363 0.23 NEDD9
 neural precursor cell expressed, developmentally down-regulated 9
 11683
 0.27
chr6_21004300_21004557 0.23 ENSG00000252046
 .
 10629
 0.32
chr10_17707589_17707769 0.23 ENSG00000251959
 .
 13508
 0.15
chr5_174487191_174487429 0.22 ENSG00000266890
 .
 308573
 0.01
chr20_18446613_18446764 0.22 DZANK1
 double zinc ribbon and ankyrin repeat domains 1
 663
 0.48
chr1_20649271_20649434 0.22 RP4-745E8.2
328
 0.9
chr3_143445457_143445608 0.22 SLC9A9
 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
 121768
 0.06
chr1_193152081_193152232 0.22 B3GALT2
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
 3628
 0.25
chrY_15815919_15816489 0.22 TMSB4Y
 thymosin beta 4, Y-linked
 757
 0.72
chr15_40112127_40112278 0.22 RP11-37C7.2
4572
 0.19
chr16_12282412_12282563 0.22 SNX29
 sorting nexin 29
 58933
 0.11
chr15_70867504_70867655 0.22 UACA
 uveal autoantigen with coiled-coil domains and ankyrin repeats
 127041
 0.06
chr9_123686452_123686718 0.22 TRAF1
 TNF receptor-associated factor 1
 4462
 0.25
chr14_57274863_57275150 0.21 OTX2
 orthodenticle homeobox 2
 2160
 0.26
chr3_189766902_189767149 0.21 ENSG00000265045
 .
 64698
 0.1
chr16_4162545_4162832 0.21 ADCY9
 adenylate cyclase 9
 1339
 0.51
chr22_34248307_34248458 0.21 LARGE
 like-glycosyltransferase
 9230
 0.27
chr18_32626039_32626502 0.21 MAPRE2
 microtubule-associated protein, RP/EB family, member 2
 4656
 0.33
chr7_15722890_15723041 0.21 MEOX2
 mesenchyme homeobox 2
 3472
 0.3
chr1_245551646_245551892 0.21 ENSG00000221165
 .
 18133
 0.26
chr17_21935353_21935504 0.21 MTRNR2L1
 MT-RNR2-like 1
 87009
 0.09
chr5_60704297_60704575 0.21 ZSWIM6
 zinc finger, SWIM-type containing 6
 76336
 0.11
chr10_17151338_17151489 0.21 CUBN
 cubilin (intrinsic factor-cobalamin receptor)
 18423
 0.23
chr17_66700653_66700804 0.21 ENSG00000263690
 .
 61972
 0.13
chr6_16135670_16135821 0.21 ENSG00000263712
 .
 6042
 0.19
chr3_108549304_108549455 0.21 TRAT1
 T cell receptor associated transmembrane adaptor 1
 7760
 0.27
chr14_62170526_62170677 0.20 HIF1A
 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
 6261
 0.26
chr4_157594550_157594701 0.20 RP11-171N4.3
30893
 0.2
chr4_1514296_1514447 0.20 NKX1-1
 NK1 homeobox 1
 114252
 0.05
chr10_33241565_33241796 0.20 ITGB1
 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 2911
 0.37
chr6_16420893_16421044 0.20 ENSG00000265642
 .
 7786
 0.31
chr9_98188423_98189086 0.20 PTCH1
 patched 1
 54013
 0.12
chr9_88206707_88206867 0.20 AGTPBP1
 ATP/GTP binding protein 1
 89414
 0.1
chr8_13346130_13346281 0.20 DLC1
 deleted in liver cancer 1
 10545
 0.24
chr12_111016409_111016682 0.19 PPTC7
 PTC7 protein phosphatase homolog (S. cerevisiae)
 4580
 0.18
chr1_172109378_172109611 0.19 ENSG00000207949
 .
 1447
 0.39
chr10_63813819_63813970 0.19 ARID5B
 AT rich interactive domain 5B (MRF1-like)
 4924
 0.3
chr2_133058367_133058560 0.19 ENSG00000221288
 .
 43810
 0.15
chr1_227501319_227501470 0.19 CDC42BPA
 CDC42 binding protein kinase alpha (DMPK-like)
 3489
 0.36
chr5_125036350_125036501 0.19 ENSG00000222107
 .
 349601
 0.01
chr13_24146066_24146217 0.19 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 1338
 0.59
chr10_28336370_28336521 0.19 ARMC4
 armadillo repeat containing 4
 48468
 0.18
chr7_24768620_24768771 0.19 DFNA5
 deafness, autosomal dominant 5
 9980
 0.29
chr7_28002200_28002423 0.19 JAZF1
 JAZF zinc finger 1
 29364
 0.22
chr5_39186752_39186903 0.19 FYB
 FYN binding protein
 16302
 0.26
chr1_158903283_158903483 0.19 PYHIN1
 pyrin and HIN domain family, member 1
 2025
 0.36
chr5_67580506_67580669 0.19 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 3609
 0.36
chr12_92534627_92535592 0.19 C12orf79
 chromosome 12 open reading frame 79
 1335
 0.39
chrX_57618068_57618312 0.19 ZXDB
 zinc finger, X-linked, duplicated B
 79
 0.99
chr10_29908483_29908634 0.19 SVIL
 supervillin
 15343
 0.18
chrX_72782625_72782944 0.18 CHIC1
 cysteine-rich hydrophobic domain 1
 252
 0.96
chr11_108040783_108041103 0.18 NPAT
 nuclear protein, ataxia-telangiectasia locus
 8051
 0.17
chr14_29254002_29254283 0.18 RP11-966I7.2
851
 0.56
chr2_25500266_25500584 0.18 DNMT3A
 DNA (cytosine-5-)-methyltransferase 3 alpha
 25245
 0.19
chr14_71454929_71455080 0.18 PCNX
 pecanex homolog (Drosophila)
 24744
 0.26
chr12_866633_866784 0.18 WNK1
 WNK lysine deficient protein kinase 1
 3976
 0.25
chr21_35306376_35306527 0.18 LINC00649
 long intergenic non-protein coding RNA 649
 2933
 0.21
chr4_169564516_169564687 0.18 RP11-610J23.1
5137
 0.22
chr7_39170814_39170965 0.18 POU6F2
 POU class 6 homeobox 2
 45428
 0.18
chr2_225809390_225809894 0.18 DOCK10
 dedicator of cytokinesis 10
 2140
 0.45
chr8_77592906_77593199 0.18 ZFHX4
 zinc finger homeobox 4
 402
 0.86
chr9_124921339_124921603 0.18 NDUFA8
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
 595
 0.48
chr3_105295301_105295452 0.18 ALCAM
 activated leukocyte cell adhesion molecule
 42930
 0.21
chrX_57022329_57022623 0.18 SPIN3
 spindlin family, member 3
 507
 0.84
chr15_60883034_60883482 0.18 RORA
 RAR-related orphan receptor A
 1482
 0.47
chr1_85247835_85247986 0.18 ENSG00000251899
 .
 10972
 0.25
chr8_95973021_95973268 0.18 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
 2908
 0.2
chr15_58920533_58921016 0.18 ENSG00000239100
 .
 28340
 0.16
chr18_34914843_34915294 0.18 RP11-797E24.3
60645
 0.13
chr17_1992653_1992959 0.18 RP11-667K14.5
169
 0.91
chr1_51447205_51447356 0.18 CDKN2C
 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
 11664
 0.2
chr8_91554264_91554415 0.18 ENSG00000199354
 .
 30983
 0.2
chr13_39610123_39610274 0.18 PROSER1
 proline and serine rich 1
 1776
 0.34
chr3_56949638_56949992 0.18 ARHGEF3
 Rho guanine nucleotide exchange factor (GEF) 3
 684
 0.75
chr13_99953854_99954138 0.18 GPR183
 G protein-coupled receptor 183
 5663
 0.22
chr9_18296716_18296867 0.17 ADAMTSL1
 ADAMTS-like 1
 177101
 0.03
chr10_51500864_51501147 0.17 AGAP7
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 7
 14678
 0.19
chr7_106822662_106822813 0.17 HBP1
 HMG-box transcription factor 1
 2374
 0.31
chr1_57041430_57041821 0.17 PPAP2B
 phosphatidic acid phosphatase type 2B
 3616
 0.34
chr2_183289734_183289997 0.17 PDE1A
 phosphodiesterase 1A, calmodulin-dependent
 1884
 0.49
chr6_26198173_26198564 0.17 HIST1H3D
 histone cluster 1, H3d
 890
 0.22
chr1_111212431_111212582 0.17 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 5149
 0.2
chr9_20041214_20041376 0.17 ENSG00000266224
 .
 211544
 0.02
chr3_170136599_170137401 0.17 CLDN11
 claudin 11
 145
 0.97
chr3_40518130_40518400 0.17 ZNF619
 zinc finger protein 619
 339
 0.84
chr11_96197527_96197689 0.17 ENSG00000200411
 .
 10248
 0.25
chr16_1584614_1584961 0.17 TMEM204
 transmembrane protein 204
 1213
 0.24
chr8_90845937_90846088 0.17 ENSG00000207359
 .
 67040
 0.11
chr15_38848503_38848654 0.17 RASGRP1
 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
 3705
 0.23
chr15_50156073_50156224 0.17 ATP8B4
 ATPase, class I, type 8B, member 4
 12744
 0.22
chr8_80739322_80739697 0.17 ENSG00000238884
 .
 27079
 0.22
chr8_94931050_94931201 0.17 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
 13
 0.98
chr5_58883529_58883730 0.17 PDE4D
 phosphodiesterase 4D, cAMP-specific
 1304
 0.62
chrX_114924538_114924731 0.17 ENSG00000264759
 .
 13498
 0.18
chr10_114291692_114291843 0.17 VTI1A
 vesicle transport through interaction with t-SNAREs 1A
 84751
 0.08
chr2_177021858_177022419 0.16 HOXD3
 homeobox D3
 3481
 0.1
chr6_127125664_127125831 0.16 ENSG00000201613
 .
 214208
 0.02
chr4_100009284_100009464 0.16 ADH5
 alcohol dehydrogenase 5 (class III), chi polypeptide
 528
 0.5
chr3_63338970_63339121 0.16 ENSG00000252662
 .
 18582
 0.26
chr6_43019642_43019793 0.16 CUL7
 cullin 7
 1720
 0.17
chrX_28607014_28607165 0.16 IL1RAPL1
 interleukin 1 receptor accessory protein-like 1
 1573
 0.57
chr17_78705219_78705370 0.16 RP11-28G8.1
74138
 0.1
chr8_38323279_38323475 0.16 FGFR1
 fibroblast growth factor receptor 1
 804
 0.6
chr12_92532725_92532888 0.16 C12orf79
 chromosome 12 open reading frame 79
 2009
 0.29
chr4_175041157_175041343 0.16 FBXO8
 F-box protein 8
 163564
 0.04
chr3_114801119_114801270 0.16 ZBTB20
 zinc finger and BTB domain containing 20
 10972
 0.32
chr14_30663660_30663811 0.16 PRKD1
 protein kinase D1
 2631
 0.43
chr4_135385341_135385492 0.16 PABPC4L
 poly(A) binding protein, cytoplasmic 4-like
 262513
 0.02
chr20_8841205_8841356 0.16 ENSG00000201348
 .
 29447
 0.23
chr18_9117636_9118003 0.16 RP11-143J12.3
1944
 0.28
chr4_107773590_107773741 0.16 DKK2
 dickkopf WNT signaling pathway inhibitor 2
 183789
 0.03
chr13_47253658_47254162 0.16 LRCH1
 leucine-rich repeats and calponin homology (CH) domain containing 1
 61
 0.99
chr8_51255795_51255946 0.16 RP11-759A9.1
37705
 0.2
chr1_111212136_111212287 0.16 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 5444
 0.2
chr11_111794495_111794677 0.16 CRYAB
 crystallin, alpha B
 140
 0.91
chr1_205717316_205717519 0.16 NUCKS1
 nuclear casein kinase and cyclin-dependent kinase substrate 1
 1987
 0.26
chr22_31317515_31317990 0.16 MORC2-AS1
 MORC2 antisense RNA 1
 543
 0.73
chr14_53575940_53576287 0.16 DDHD1
 DDHD domain containing 1
 40691
 0.14
chr11_128559988_128560195 0.16 FLI1
 Fli-1 proto-oncogene, ETS transcription factor
 2298
 0.26
chr7_122115813_122115964 0.16 CADPS2
 Ca++-dependent secretion activator 2
 37458
 0.19
chr14_50862384_50862648 0.16 CDKL1
 cyclin-dependent kinase-like 1 (CDC2-related kinase)
 101
 0.97
chr22_50318944_50319095 0.16 CRELD2
 cysteine-rich with EGF-like domains 2
 6638
 0.17
chr3_73606637_73606788 0.16 PDZRN3
 PDZ domain containing ring finger 3
 4057
 0.29
chr21_39807445_39807798 0.16 ERG
 v-ets avian erythroblastosis virus E26 oncogene homolog
 62724
 0.14
chr10_63999686_63999837 0.16 RTKN2
 rhotekin 2
 3739
 0.34
chr2_204572133_204572358 0.16 CD28
 CD28 molecule
 829
 0.71
chr7_94025506_94025990 0.16 COL1A2
 collagen, type I, alpha 2
 1875
 0.46
chr14_52778615_52778779 0.16 PTGER2
 prostaglandin E receptor 2 (subtype EP2), 53kDa
 2326
 0.38
chr10_123733699_123733904 0.15 NSMCE4A
 non-SMC element 4 homolog A (S. cerevisiae)
 472
 0.82
chr6_154691911_154692077 0.15 IPCEF1
 interaction protein for cytohesin exchange factors 1
 14068
 0.27
chr6_143501955_143502106 0.15 AIG1
 androgen-induced 1
 54643
 0.14
chr1_10341352_10341503 0.15 ENSG00000199562
 .
 17597
 0.15
chr12_14520726_14520877 0.15 ATF7IP
 activating transcription factor 7 interacting protein
 494
 0.85
chr14_71933799_71933950 0.15 ENSG00000242330
 .
 18468
 0.23
chrX_53356672_53356823 0.15 ENSG00000207408
 .
 2980
 0.23
chr8_101731752_101732025 0.15 PABPC1
 poly(A) binding protein, cytoplasmic 1
 1770
 0.27
chr4_39032194_39032374 0.15 TMEM156
 transmembrane protein 156
 1757
 0.38
chr8_135790318_135790469 0.15 ENSG00000207582
 .
 22457
 0.21
chr15_44120227_44120469 0.15 WDR76
 WD repeat domain 76
 1162
 0.29
chr7_18794250_18794418 0.15 ENSG00000222164
 .
 53568
 0.17
chr2_197662576_197662727 0.15 GTF3C3
 general transcription factor IIIC, polypeptide 3, 102kDa
 1732
 0.37
chr3_12436703_12437398 0.15 PPARG
 peroxisome proliferator-activated receptor gamma
 44079
 0.15
chr2_155000932_155001083 0.15 ENSG00000266512
 .
 1713
 0.51
chr3_95425254_95425405 0.15 ENSG00000221477
 .
 460417
 0.01
chr3_121964996_121965193 0.15 ENSG00000252170
 .
 481
 0.79
chr3_135284920_135285071 0.15 ENSG00000253004
 .
 233627
 0.02

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC6_HOXA7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.5 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.2 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:1904035 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.0 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.1 GO:0070933 histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.1 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:1900116 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.0 0.2 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.1 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:1903521 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0072007 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.0 0.1 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.1 GO:0002335 mature B cell differentiation(GO:0002335)
0.0 0.0 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0010510 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0009151 purine deoxyribonucleotide metabolic process(GO:0009151)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0061364 apoptotic process involved in luteolysis(GO:0061364)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.0 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:1903960 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.1 GO:0070071 proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0072203 cell proliferation involved in metanephros development(GO:0072203)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.0 GO:0008049 male courtship behavior(GO:0008049)
0.0 0.0 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.0 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.0 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.1 GO:0051503 adenine nucleotide transport(GO:0051503)
0.0 0.1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0009120 deoxyribonucleoside metabolic process(GO:0009120)
0.0 0.1 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.0 GO:1901978 positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:0000080 mitotic G1 phase(GO:0000080)
0.0 0.1 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.0 GO:0015853 adenine transport(GO:0015853)
0.0 0.0 GO:0031579 membrane raft organization(GO:0031579)
0.0 0.0 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.0 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.0 GO:0032898 neurotrophin production(GO:0032898)
0.0 0.0 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.0 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:1900078 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0010829 negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:0048867 stem cell fate commitment(GO:0048865) stem cell fate determination(GO:0048867)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0031000 response to caffeine(GO:0031000)
0.0 0.1 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.0 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.0 GO:0014850 response to muscle activity(GO:0014850)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.0 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094) platelet dense tubular network membrane(GO:0031095)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.0 GO:0005787 signal peptidase complex(GO:0005787)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.1 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.0 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0003709 obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.0 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.0 GO:0032554 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.0 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.0 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.2 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.0 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.5 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane