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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXC8

Z-value: 3.86

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Transcription factors associated with HOXC8

Gene Symbol	Gene ID	Gene Info
HOXC8 Ensembl NCBI GeneCards UniProt	ENSG00000037965.4	homeobox C8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr12_54402288_54402544	HOXC8	416	0.594755	0.72	2.7e-02	Click!
chr12_54398329_54398480	HOXC8	4428	0.067583	0.71	3.1e-02	Click!
chr12_54401824_54401975	HOXC8	933	0.269281	0.67	4.9e-02	Click!
chr12_54402091_54402242	HOXC8	666	0.394225	0.57	1.1e-01	Click!
chr12_54404190_54404341	HOXC8	1433	0.162959	0.57	1.1e-01	Click!

Activity of the HOXC8 motif across conditions

Conditions sorted by the z-value of the HOXC8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_18474095_18474958	2.50	ADAMTSL1	ADAMTS-like 1	295	0.95
chr10_33620428_33620906	2.43	NRP1	neuropilin 1	2643	0.37
chr15_96878987_96879612	2.00	ENSG00000222651	.	2809	0.21
chr4_157891142_157892336	1.85	PDGFC	platelet derived growth factor C	316	0.91
chr12_59311038_59311457	1.83	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr7_41740779_41741576	1.77	INHBA	inhibin, beta A	970	0.56
chrX_114467670_114468385	1.73	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	601	0.77
chr3_87036535_87037613	1.73	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chrX_28605228_28605520	1.72	IL1RAPL1	interleukin 1 receptor accessory protein-like 1	142	0.98
chr11_121967218_121967559	1.71	ENSG00000207971	.	3164	0.21
chr6_152701268_152701555	1.66	SYNE1-AS1	SYNE1 antisense RNA 1	270	0.91
chr8_19148668_19149118	1.64	SH2D4A	SH2 domain containing 4A	22235	0.28
chr1_243415347_243415602	1.62	CEP170	centrosomal protein 170kDa	1148	0.47
chr10_114714851_114715858	1.61	RP11-57H14.2		3720	0.26
chr7_130596201_130596683	1.59	ENSG00000226380	.	34144	0.19
chr8_42063953_42065062	1.59	PLAT	plasminogen activator, tissue	576	0.71
chr2_158113918_158114875	1.58	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr9_12859535_12860149	1.55	ENSG00000222658	.	25478	0.2
chr21_17677767_17678526	1.53	ENSG00000201025	.	21057	0.28
chr15_99788624_99789059	1.52	TTC23	tetratricopeptide repeat domain 23	895	0.51
chr7_94025506_94025990	1.50	COL1A2	collagen, type I, alpha 2	1875	0.46
chr4_114899439_114899761	1.46	ARSJ	arylsulfatase family, member J	552	0.84
chr7_78398482_78399243	1.41	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1534	0.56
chr3_157250255_157250502	1.37	VEPH1	ventricular zone expressed PH domain-containing 1	1017	0.61
chr6_85823864_85824548	1.37	NT5E	5'-nucleotidase, ecto (CD73)	335603	0.01
chr15_70994402_70994652	1.37	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	93	0.98
chr20_14317720_14318261	1.36	FLRT3	fibronectin leucine rich transmembrane protein 3	264	0.94
chr2_164591489_164591640	1.36	FIGN	fidgetin	953	0.74
chr7_80547175_80548098	1.35	SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	863	0.76
chr2_36581700_36582677	1.34	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	881	0.74
chr9_27276437_27276611	1.33	EQTN	equatorin, sperm acrosome associated	20610	0.24
chr6_121757423_121758012	1.33	GJA1	gap junction protein, alpha 1, 43kDa	879	0.59
chr8_49832237_49832502	1.33	SNAI2	snail family zinc finger 2	1619	0.54
chr6_19691587_19692480	1.32	ENSG00000200957	.	49273	0.18
chr12_88972313_88972545	1.29	KITLG	KIT ligand	1809	0.39
chr15_37179413_37179956	1.28	ENSG00000212511	.	34843	0.22
chr11_27722222_27723091	1.28	BDNF	brain-derived neurotrophic factor	56	0.98
chr18_56245541_56245920	1.27	RP11-126O1.2		21428	0.14
chr5_91977319_91977616	1.27	ENSG00000221810	.	75753	0.13
chr8_127837007_127837644	1.25	ENSG00000212451	.	153558	0.04
chr3_55514769_55515136	1.24	WNT5A	wingless-type MMTV integration site family, member 5A	272	0.94
chr7_120631344_120631706	1.24	CPED1	cadherin-like and PC-esterase domain containing 1	1849	0.35
chr2_216299709_216300678	1.24	FN1	fibronectin 1	597	0.55
chr15_30112674_30113382	1.23	TJP1	tight junction protein 1	723	0.64
chr3_126500993_126501380	1.23	CHCHD6	coiled-coil-helix-coiled-coil-helix domain containing 6	51779	0.16
chr5_174162455_174162926	1.23	MSX2	msh homeobox 2	11085	0.25
chr18_53089837_53090372	1.23	TCF4	transcription factor 4	361	0.89
chr14_52707563_52708006	1.21	PTGDR	prostaglandin D2 receptor (DP)	26647	0.22
chr9_21677527_21678485	1.20	ENSG00000244230	.	21307	0.21
chr17_75316367_75316959	1.20	SEPT9	septin 9	268	0.93
chr1_7130330_7130574	1.20	RP11-334N17.1		56113	0.15
chr7_151433344_151433930	1.20	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	237	0.95
chr4_71588718_71588869	1.19	RUFY3	RUN and FYVE domain containing 3	421	0.76
chr3_181434209_181434555	1.19	SOX2	SRY (sex determining region Y)-box 2	4660	0.26
chr18_55468661_55468977	1.19	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	1508	0.47
chr11_121969171_121969347	1.19	ENSG00000207971	.	1293	0.36
chr17_32582682_32583141	1.19	AC005549.3	Uncharacterized protein	605	0.41
chr4_151500337_151500655	1.18	RP11-1336O20.2		255	0.93
chr6_19838575_19839711	1.16	RP1-167F1.2		168	0.95
chr7_27191312_27191528	1.16	HOXA-AS3	HOXA cluster antisense RNA 3	1749	0.13
chr5_169406633_169406826	1.16	FAM196B	family with sequence similarity 196, member B	1015	0.64
chr4_41215270_41215769	1.15	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	956	0.59
chr17_59476045_59476898	1.14	RP11-332H18.4		260	0.74
chr10_60273912_60274168	1.14	BICC1	bicaudal C homolog 1 (Drosophila)	1140	0.65
chr12_10868992_10869331	1.13	YBX3	Y box binding protein 3	6745	0.18
chr3_15837119_15837337	1.13	ANKRD28	ankyrin repeat domain 28	800	0.67
chr1_65005729_65006114	1.12	ENSG00000264470	.	39609	0.19
chr14_39716196_39716541	1.12	MIA2	melanoma inhibitory activity 2	13049	0.14
chr1_163040363_163040678	1.11	RGS4	regulator of G-protein signaling 4	1314	0.56
chr9_21558481_21558945	1.10	MIR31HG	MIR31 host gene (non-protein coding)	955	0.56
chr9_22008020_22008450	1.10	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	717	0.61
chr3_149094469_149095370	1.10	TM4SF1-AS1	TM4SF1 antisense RNA 1	646	0.47
chr21_17960305_17960805	1.09	ENSG00000207863	.	2002	0.4
chr22_36233928_36234199	1.08	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2202	0.43
chr11_121968787_121969071	1.08	ENSG00000207971	.	1623	0.3
chr1_153584096_153584410	1.08	S100A16	S100 calcium binding protein A16	1306	0.22
chr8_92612283_92612746	1.07	ENSG00000200151	.	5321	0.33
chr3_149372263_149372653	1.07	WWTR1-AS1	WWTR1 antisense RNA 1	2349	0.24
chr4_81191707_81191903	1.07	FGF5	fibroblast growth factor 5	4012	0.29
chr4_23890359_23890765	1.06	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	1096	0.66
chr2_190042287_190042516	1.05	COL5A2	collagen, type V, alpha 2	2204	0.37
chr5_98111445_98111873	1.05	RGMB	repulsive guidance molecule family member b	2320	0.3
chr3_93895824_93896204	1.05	ENSG00000253062	.	78604	0.1
chr5_124078870_124079512	1.05	ZNF608	zinc finger protein 608	1023	0.42
chr4_89977525_89978081	1.05	FAM13A	family with sequence similarity 13, member A	508	0.85
chr4_71589225_71589655	1.05	RUFY3	RUN and FYVE domain containing 3	1068	0.4
chr18_53090404_53090609	1.03	TCF4	transcription factor 4	763	0.7
chr13_24145467_24145689	1.03	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	775	0.77
chr4_125632186_125632438	1.02	ANKRD50	ankyrin repeat domain 50	1575	0.58
chr15_97778812_97779147	1.02	ENSG00000242863	.	117748	0.06
chr18_53525579_53526226	1.01	TCF4	transcription factor 4	193884	0.03
chr10_33622034_33622426	1.01	NRP1	neuropilin 1	1080	0.63
chr15_56208525_56208789	1.01	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	649	0.78
chr4_134068181_134068851	1.01	PCDH10	protocadherin 10	1954	0.52
chr4_187590867_187591207	1.01	FAT1	FAT atypical cadherin 1	53972	0.15
chr19_6076963_6077580	1.00	CTC-232P5.3		9307	0.15
chr1_227504354_227504526	1.00	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	443	0.9
chr8_49833429_49833759	1.00	SNAI2	snail family zinc finger 2	394	0.92
chr6_121756849_121757212	0.99	GJA1	gap junction protein, alpha 1, 43kDa	192	0.94
chr6_38230060_38230313	0.99	ENSG00000200706	.	55136	0.16
chr5_16933613_16934070	0.99	MYO10	myosin X	2206	0.34
chr18_74798828_74799607	0.99	MBP	myelin basic protein	18000	0.27
chr2_199965342_199965661	0.98	ENSG00000238698	.	90281	0.1
chr5_158488269_158488591	0.98	EBF1	early B-cell factor 1	38271	0.17
chr13_24146066_24146217	0.98	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	1338	0.59
chr20_47961894_47962163	0.97	ENSG00000212304	.	64808	0.08
chr15_39803785_39804214	0.97	THBS1	thrombospondin 1	69281	0.1
chr13_65834890_65835427	0.97	ENSG00000221685	.	603147	0.0
chr3_87039220_87039752	0.97	VGLL3	vestigial like 3 (Drosophila)	366	0.93
chr8_49447973_49448420	0.96	RP11-770E5.1		15931	0.3
chr21_17909068_17909746	0.96	ENSG00000207638	.	2002	0.33
chr19_39465324_39465724	0.96	FBXO17	F-box protein 17	1026	0.37
chr10_93443563_93443860	0.96	PPP1R3C	protein phosphatase 1, regulatory subunit 3C	50900	0.16
chr12_64238850_64239338	0.95	SRGAP1	SLIT-ROBO Rho GTPase activating protein 1	553	0.72
chr22_46461260_46461448	0.95	RP6-109B7.4		4417	0.11
chr10_29824642_29824876	0.95	ENSG00000207612	.	9267	0.19
chr6_148829582_148830289	0.95	ENSG00000223322	.	15441	0.29
chr5_88120627_88121096	0.94	MEF2C	myocyte enhancer factor 2C	704	0.78
chr12_66286178_66286489	0.94	RP11-366L20.2	Uncharacterized protein	10386	0.18
chr2_151336714_151337073	0.94	RND3	Rho family GTPase 3	5003	0.36
chr16_86604206_86604444	0.94	RP11-463O9.5		2958	0.2
chr15_72529055_72529849	0.94	PKM	pyruvate kinase, muscle	5288	0.17
chr1_45083000_45083241	0.94	RNF220	ring finger protein 220	8878	0.17
chr10_33620140_33620362	0.93	NRP1	neuropilin 1	3059	0.34
chr7_116141197_116141631	0.93	CAV2	caveolin 2	1580	0.29
chr1_95388573_95389173	0.93	CNN3	calponin 3, acidic	2464	0.27
chr15_60683019_60683395	0.93	ANXA2	annexin A2	119	0.98
chr5_57752262_57752636	0.92	PLK2	polo-like kinase 2	3638	0.28
chr12_132268914_132269167	0.92	ENSG00000200516	.	16939	0.16
chr12_91574306_91575101	0.92	DCN	decorin	50	0.99
chr2_5830994_5831186	0.91	AC108025.2		88	0.88
chr12_56916774_56917003	0.91	RBMS2	RNA binding motif, single stranded interacting protein 2	1105	0.41
chr4_123795073_123795451	0.91	RP11-170N16.3		10605	0.18
chr6_155005040_155005564	0.90	SCAF8	SR-related CTD-associated factor 8	49157	0.17
chr9_111205795_111206154	0.90	ENSG00000222512	.	84765	0.11
chr6_8434475_8434734	0.89	SLC35B3	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	1112	0.69
chr12_85305306_85305778	0.89	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	261	0.96
chr8_25042452_25043634	0.89	DOCK5	dedicator of cytokinesis 5	663	0.75
chr1_98496636_98496977	0.88	ENSG00000225206	.	14101	0.3
chr22_46462951_46463814	0.88	RP6-109B7.4		2389	0.16
chr18_74300716_74301068	0.88	LINC00908	long intergenic non-protein coding RNA 908	60018	0.12
chr4_88939495_88939878	0.88	PKD2	polycystic kidney disease 2 (autosomal dominant)	10866	0.19
chr5_78808053_78808300	0.88	HOMER1	homer homolog 1 (Drosophila)	441	0.86
chr19_30719241_30719606	0.88	ZNF536	zinc finger protein 536	2	0.73
chr11_84598351_84598627	0.88	DLG2	discs, large homolog 2 (Drosophila)	35735	0.2
chr19_49661333_49661989	0.87	TRPM4	transient receptor potential cation channel, subfamily M, member 4	562	0.58
chr5_115313493_115313761	0.87	AQPEP	Aminopeptidase Q	15436	0.17
chr6_3749707_3750198	0.87	RP11-420L9.5		1393	0.41
chr5_31193803_31195028	0.87	CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	558	0.85
chr2_190068990_190069191	0.87	COL5A2	collagen, type V, alpha 2	24485	0.21
chr10_92679511_92679800	0.87	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	1378	0.39
chr7_17720120_17720505	0.87	SNX13	sorting nexin 13	259779	0.02
chr3_33318777_33319866	0.87	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr6_114181963_114182196	0.87	MARCKS	myristoylated alanine-rich protein kinase C substrate	3538	0.24
chr1_68697735_68698156	0.87	WLS	wntless Wnt ligand secretion mediator	18	0.98
chr13_24079253_24079588	0.86	TNFRSF19	tumor necrosis factor receptor superfamily, member 19	65089	0.13
chr6_163840513_163841070	0.86	QKI	QKI, KH domain containing, RNA binding	3375	0.39
chr1_221165731_221165981	0.86	HLX	H2.0-like homeobox	111272	0.06
chr3_64670816_64671530	0.86	ADAMTS9-AS2	ADAMTS9 antisense RNA 2	369	0.87
chr4_138450639_138450790	0.86	PCDH18	protocadherin 18	2851	0.43
chr8_16689434_16690090	0.86	ENSG00000264092	.	31243	0.24
chr6_8109014_8109165	0.86	EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	6278	0.27
chr7_95402477_95402695	0.86	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	670	0.81
chr5_172753269_172753420	0.86	STC2	stanniocalcin 2	456	0.82
chr11_121970307_121971111	0.85	ENSG00000207971	.	157	0.79
chr14_52121528_52121679	0.85	FRMD6	FERM domain containing 6	2905	0.27
chr3_97590789_97591003	0.85	CRYBG3	beta-gamma crystallin domain containing 3	4923	0.28
chr2_221969079_221969387	0.85	EPHA4	EPH receptor A4	398047	0.01
chr1_24476638_24476996	0.85	IL22RA1	interleukin 22 receptor, alpha 1	7206	0.17
chr1_179111876_179112093	0.84	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	195	0.95
chr3_44063258_44064101	0.84	ENSG00000252980	.	48900	0.17
chr2_227590884_227591406	0.84	ENSG00000263363	.	67636	0.11
chr8_23711375_23711668	0.84	STC1	stanniocalcin 1	303	0.92
chr12_91576386_91576586	0.84	DCN	decorin	0	0.99
chr12_19358566_19358717	0.84	PLEKHA5	pleckstrin homology domain containing, family A member 5	382	0.89
chr12_97469704_97469855	0.84	ENSG00000202368	.	96372	0.09
chr6_88875424_88876640	0.84	CNR1	cannabinoid receptor 1 (brain)	46	0.99
chr15_38547811_38548278	0.84	SPRED1	sprouty-related, EVH1 domain containing 1	2662	0.42
chr4_41204622_41204773	0.84	APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	11778	0.2
chr22_47486867_47487445	0.84	ENSG00000221672	.	243353	0.02
chr1_201509442_201509672	0.84	CSRP1	cysteine and glycine-rich protein 1	30973	0.13
chr1_196621837_196622284	0.84	CFH	complement factor H	874	0.67
chr1_224075422_224075812	0.83	TP53BP2	tumor protein p53 binding protein, 2	41943	0.17
chr1_8262367_8262761	0.83	ENSG00000200975	.	4093	0.27
chr11_12714851_12715219	0.83	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	17985	0.26
chr12_117036919_117037510	0.83	MAP1LC3B2	microtubule-associated protein 1 light chain 3 beta 2	23558	0.24
chr3_114619517_114619967	0.83	ZBTB20	zinc finger and BTB domain containing 20	141624	0.05
chr7_70201396_70202343	0.83	AUTS2	autism susceptibility candidate 2	7744	0.34
chr4_143739251_143739537	0.83	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	28049	0.27
chr9_16726683_16727481	0.82	RP11-62F24.2		270	0.85
chr4_54063057_54063462	0.82	ENSG00000207385	.	68475	0.13
chr2_38828054_38829790	0.82	AC011247.3		182	0.89
chr1_81703498_81704139	0.82	ENSG00000223026	.	13656	0.28
chr15_39874864_39875069	0.82	THBS1	thrombospondin 1	1672	0.37
chr8_122649996_122650341	0.82	HAS2-AS1	HAS2 antisense RNA 1	1365	0.48
chr2_25841069_25841672	0.82	DTNB	dystrobrevin, beta	31723	0.2
chr5_102202832_102203172	0.82	PAM	peptidylglycine alpha-amidating monooxygenase	1182	0.66
chr9_80437599_80437890	0.82	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	171	0.98
chr8_16612533_16612758	0.82	ENSG00000264092	.	108360	0.07
chr5_82767889_82768074	0.81	VCAN	versican	237	0.96

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	6.9	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
1.3	3.9	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.2	3.5	GO:0051964	negative regulation of synapse assembly(GO:0051964)
1.1	3.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.9	3.6	GO:0043589	skin morphogenesis(GO:0043589)
0.8	2.4	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.8	2.4	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.8	2.3	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.8	1.5	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.7	0.7	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.7	2.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.7	2.7	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.6	3.7	GO:0016264	gap junction assembly(GO:0016264)
0.6	2.5	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.6	1.2	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.6	0.6	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.6	1.7	GO:0031223	auditory behavior(GO:0031223)
0.6	2.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.6	2.8	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.5	0.5	GO:0010193	response to ozone(GO:0010193)
0.5	1.6	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.5	1.6	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.5	4.3	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.5	1.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.5	4.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.5	0.5	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.5	1.5	GO:0030210	heparin biosynthetic process(GO:0030210)
0.5	1.5	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.5	2.0	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.5	3.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.5	0.9	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.5	2.3	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.5	1.4	GO:2000095	regulation of non-canonical Wnt signaling pathway(GO:2000050) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.4	0.4	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.4	1.3	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.4	1.3	GO:0060596	mammary placode formation(GO:0060596)
0.4	3.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.4	2.5	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.4	1.6	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.4	1.2	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.4	1.2	GO:0043615	astrocyte cell migration(GO:0043615)
0.4	0.8	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.4	1.2	GO:0060677	ureteric bud elongation(GO:0060677)
0.4	1.5	GO:0008218	bioluminescence(GO:0008218)
0.4	0.4	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.4	1.1	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.4	1.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4	2.5	GO:0060259	regulation of feeding behavior(GO:0060259)
0.4	3.2	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.3	1.0	GO:0008354	germ cell migration(GO:0008354)
0.3	7.7	GO:0030199	collagen fibril organization(GO:0030199)
0.3	0.3	GO:0032344	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.3	1.0	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.3	1.0	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.3	2.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.3	2.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.3	0.9	GO:0010842	retina layer formation(GO:0010842)
0.3	1.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.3	0.6	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.3	1.2	GO:0010800	positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.3	0.9	GO:0060013	righting reflex(GO:0060013)
0.3	2.5	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.3	0.6	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.3	1.2	GO:0010667	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.3	0.6	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.3	1.7	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.3	1.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.3	1.7	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.3	0.6	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.3	0.8	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	0.5	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.3	1.6	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.3	0.5	GO:0072070	loop of Henle development(GO:0072070)
0.3	1.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.3	0.3	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.3	0.5	GO:0060242	contact inhibition(GO:0060242)
0.3	2.1	GO:0071320	cellular response to cAMP(GO:0071320)
0.3	0.8	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.3	0.8	GO:0051451	myoblast migration(GO:0051451)
0.3	0.5	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	1.2	GO:0014850	response to muscle activity(GO:0014850)
0.2	1.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	0.2	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.2	0.2	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.2	0.2	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.2	0.7	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.7	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2	0.7	GO:0048539	bone marrow development(GO:0048539)
0.2	0.7	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.2	0.9	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.2	0.7	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.2	0.2	GO:0090190	ureteric bud formation(GO:0060676) positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.2	3.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.2	0.2	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.2	0.5	GO:0060437	lung growth(GO:0060437)
0.2	1.6	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.2	2.9	GO:0042474	middle ear morphogenesis(GO:0042474)
0.2	3.7	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.2	0.2	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.2	0.9	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	0.6	GO:0016576	histone dephosphorylation(GO:0016576)
0.2	0.2	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2	0.2	GO:0060435	bronchiole development(GO:0060435)
0.2	0.8	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.2	0.8	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.2	2.9	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.2	4.4	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2	0.4	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.2	0.4	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.2	0.8	GO:0034063	stress granule assembly(GO:0034063)
0.2	0.6	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.2	0.8	GO:0016266	O-glycan processing(GO:0016266)
0.2	0.2	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.2	0.2	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2	0.4	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.2	1.1	GO:0008347	glial cell migration(GO:0008347)
0.2	0.2	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.2	0.4	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.2	0.6	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.2	0.8	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.2	0.4	GO:0050955	thermoception(GO:0050955)
0.2	0.6	GO:0060073	urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.2	0.4	GO:1903170	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.2	0.2	GO:0051310	metaphase plate congression(GO:0051310)
0.2	0.5	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.2	4.2	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.2	0.7	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.2	0.7	GO:0007413	axonal fasciculation(GO:0007413)
0.2	0.5	GO:0001945	lymph vessel development(GO:0001945)
0.2	0.5	GO:0051182	coenzyme transport(GO:0051182)
0.2	0.2	GO:0030812	negative regulation of nucleotide catabolic process(GO:0030812) negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.2	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.2	0.5	GO:0032455	nerve growth factor processing(GO:0032455)
0.2	0.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.2	1.0	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.2	1.2	GO:0010092	organ induction(GO:0001759) specification of organ identity(GO:0010092)
0.2	0.7	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.2	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.5	GO:1903332	regulation of protein folding(GO:1903332)
0.2	0.5	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.2	0.5	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.2	0.5	GO:0000103	sulfate assimilation(GO:0000103)
0.2	1.0	GO:0060039	pericardium development(GO:0060039)
0.2	0.2	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.2	0.8	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.2	1.6	GO:0043113	receptor clustering(GO:0043113)
0.2	0.5	GO:0032836	glomerular basement membrane development(GO:0032836)
0.2	0.5	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.2	0.2	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.2	0.3	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.2	1.7	GO:0035329	hippo signaling(GO:0035329)
0.2	0.5	GO:0051014	actin filament severing(GO:0051014)
0.2	0.3	GO:0060206	estrous cycle phase(GO:0060206)
0.2	0.2	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.2	0.2	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.2	0.3	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.7	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.1	0.9	GO:0007350	blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.7	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.4	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.1	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656)
0.1	0.4	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.1	0.7	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1	0.3	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.6	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.4	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	1.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.1	0.6	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.7	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.1	0.1	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	0.1	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.3	GO:0007100	mitotic centrosome separation(GO:0007100)
0.1	0.4	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.4	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.4	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.4	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	1.2	GO:0071453	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.1	0.5	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.1	0.5	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.3	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.9	GO:0031290	retinal ganglion cell axon guidance(GO:0031290)
0.1	16.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.6	GO:0032288	myelin assembly(GO:0032288)
0.1	0.3	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.1	0.1	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.1	0.4	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.1	1.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.8	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.1	2.6	GO:0001843	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1	1.0	GO:0031000	response to caffeine(GO:0031000)
0.1	0.1	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.5	GO:0001660	fever generation(GO:0001660)
0.1	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.1	GO:0021546	rhombomere development(GO:0021546)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.1	GO:0061037	negative regulation of cartilage development(GO:0061037)
0.1	0.2	GO:0048840	otolith development(GO:0048840)
0.1	0.1	GO:0071294	cellular response to zinc ion(GO:0071294)
0.1	0.5	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.6	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.2	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.1	0.1	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1	0.4	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.3	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.7	GO:0008038	neuron recognition(GO:0008038)
0.1	0.9	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.2	GO:0030432	peristalsis(GO:0030432)
0.1	0.1	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	0.3	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1	0.4	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.1	1.5	GO:0060348	bone development(GO:0060348)
0.1	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1	0.7	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.2	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1	2.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.5	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	1.1	GO:0031114	negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1	1.5	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.1	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.1	0.4	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1	0.6	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.1	0.6	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.1	0.5	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.1	0.3	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.7	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.4	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	1.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.5	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.5	GO:0003151	outflow tract morphogenesis(GO:0003151)
0.1	0.2	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.3	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	2.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.4	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1	0.2	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.1	2.4	GO:0001649	osteoblast differentiation(GO:0001649)
0.1	0.3	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.1	0.5	GO:0002076	osteoblast development(GO:0002076)
0.1	2.4	GO:0022405	hair follicle development(GO:0001942) molting cycle process(GO:0022404) hair cycle process(GO:0022405) skin epidermis development(GO:0098773)
0.1	0.6	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.1	0.3	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.8	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.5	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.1	0.4	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.1	0.4	GO:0010107	potassium ion import(GO:0010107)
0.1	1.8	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.1	0.8	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.3	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	1.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.3	GO:0009648	photoperiodism(GO:0009648)
0.1	0.4	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.1	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.2	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	0.2	GO:0060079	excitatory postsynaptic potential(GO:0060079)
0.1	0.2	GO:0019731	antibacterial humoral response(GO:0019731)
0.1	0.3	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.1	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.4	GO:0048636	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.1	1.6	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.3	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.3	GO:0045901	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.1	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.4	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.1	0.8	GO:0045429	positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1	0.2	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.1	0.2	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.1	GO:0031645	negative regulation of neurological system process(GO:0031645)
0.1	0.2	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.3	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0021521	ventral spinal cord interneuron specification(GO:0021521) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913) cell fate specification involved in pattern specification(GO:0060573)
0.1	0.2	GO:0016246	RNA interference(GO:0016246)
0.1	0.2	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	1.0	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.2	GO:0033632	regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.3	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.2	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.1	0.2	GO:0007494	midgut development(GO:0007494)
0.1	0.2	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1	1.7	GO:0051101	regulation of DNA binding(GO:0051101)
0.1	0.2	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.1	0.2	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.1	0.3	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1	0.2	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	0.7	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.3	GO:0034501	protein localization to kinetochore(GO:0034501)
0.1	0.2	GO:0007619	courtship behavior(GO:0007619) male courtship behavior(GO:0008049)
0.1	0.2	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	1.3	GO:0019233	sensory perception of pain(GO:0019233)
0.1	0.6	GO:0006108	malate metabolic process(GO:0006108)
0.1	0.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.1	0.4	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	1.1	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	2.6	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1	0.4	GO:0015840	urea transport(GO:0015840)
0.1	0.1	GO:0007412	axon target recognition(GO:0007412)
0.1	0.3	GO:0048566	embryonic digestive tract development(GO:0048566)
0.1	0.3	GO:0030488	tRNA methylation(GO:0030488)
0.1	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.1	GO:2000379	positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1	1.1	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.1	0.4	GO:0032373	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.1	0.2	GO:0051409	response to nitrosative stress(GO:0051409)
0.1	0.2	GO:0046469	platelet activating factor metabolic process(GO:0046469)
0.1	0.4	GO:0006477	protein sulfation(GO:0006477)
0.1	0.8	GO:0008210	estrogen metabolic process(GO:0008210)
0.1	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.2	GO:0030146	obsolete diuresis(GO:0030146)
0.1	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.3	GO:0060192	negative regulation of lipoprotein lipase activity(GO:0051005) negative regulation of lipase activity(GO:0060192)
0.1	0.1	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.1	0.2	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	0.1	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1	0.2	GO:0046952	ketone body catabolic process(GO:0046952)
0.1	0.1	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.1	0.1	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.1	0.4	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1	0.5	GO:0046653	tetrahydrofolate metabolic process(GO:0046653)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.2	GO:0043114	regulation of vascular permeability(GO:0043114)
0.1	0.2	GO:0006591	ornithine metabolic process(GO:0006591)
0.1	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.1	0.1	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.1	0.2	GO:0048512	circadian sleep/wake cycle(GO:0042745) circadian behavior(GO:0048512)
0.1	0.1	GO:0060795	cell fate commitment involved in formation of primary germ layer(GO:0060795)
0.1	0.6	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.1	0.3	GO:0050872	white fat cell differentiation(GO:0050872)
0.1	0.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.1	0.3	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.1	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.1	1.0	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.1	0.4	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.5	GO:0006893	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.1	0.2	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.1	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.2	GO:0015811	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.1	0.3	GO:0060674	placenta blood vessel development(GO:0060674)
0.1	0.3	GO:0007616	long-term memory(GO:0007616)
0.1	1.1	GO:0071772	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.1	0.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.1	0.5	GO:0014075	response to amine(GO:0014075)
0.1	0.1	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.1	GO:0050957	equilibrioception(GO:0050957)
0.1	0.1	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.1	0.8	GO:0009250	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	0.7	GO:0014047	glutamate secretion(GO:0014047)
0.1	0.2	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.2	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.3	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.2	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.4	GO:0007613	memory(GO:0007613)
0.0	0.5	GO:0034605	cellular response to heat(GO:0034605)
0.0	0.1	GO:0071600	otic vesicle formation(GO:0030916) otic vesicle development(GO:0071599) otic vesicle morphogenesis(GO:0071600)
0.0	0.0	GO:0060745	mammary gland branching involved in pregnancy(GO:0060745)
0.0	0.1	GO:0045002	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	5.5	GO:0006936	muscle contraction(GO:0006936)
0.0	0.0	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.7	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
0.0	0.1	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.3	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.2	GO:0046113	nucleobase catabolic process(GO:0046113)
0.0	0.1	GO:0016115	vitamin catabolic process(GO:0009111) diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.1	GO:0001885	endothelial cell development(GO:0001885)
0.0	0.2	GO:0032963	collagen metabolic process(GO:0032963)
0.0	0.4	GO:0050931	melanocyte differentiation(GO:0030318) pigment cell differentiation(GO:0050931)
0.0	0.0	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.1	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.0	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0	0.2	GO:0010744	positive regulation of macrophage derived foam cell differentiation(GO:0010744)
0.0	0.0	GO:0030878	thyroid gland development(GO:0030878)
0.0	0.2	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.1	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.2	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.4	GO:0001508	action potential(GO:0001508)
0.0	0.4	GO:0001895	retina homeostasis(GO:0001895)
0.0	0.1	GO:0050807	regulation of synapse organization(GO:0050807)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.2	GO:0035088	establishment or maintenance of apical/basal cell polarity(GO:0035088) establishment or maintenance of bipolar cell polarity(GO:0061245)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	2.7	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.4	GO:0007492	endoderm development(GO:0007492)
0.0	0.1	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:0035094	response to nicotine(GO:0035094)
0.0	0.1	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.0	GO:0042519	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.0	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.0	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0051703	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.2	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0060438	trachea development(GO:0060438)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.0	GO:0035637	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.2	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.2	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.0	GO:0034695	response to prostaglandin E(GO:0034695)
0.0	0.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0000097	sulfur amino acid biosynthetic process(GO:0000097)
0.0	0.1	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.0	0.1	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.2	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.2	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.3	GO:0060828	regulation of canonical Wnt signaling pathway(GO:0060828)
0.0	0.4	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0051904	pigment granule transport(GO:0051904)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.3	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.3	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.0	GO:0055010	ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0	0.1	GO:0051593	response to folic acid(GO:0051593)
0.0	0.3	GO:0001657	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0	0.1	GO:0051938	L-glutamate import(GO:0051938)
0.0	0.1	GO:0090102	cochlea development(GO:0090102)
0.0	0.2	GO:0045132	meiotic chromosome segregation(GO:0045132)
0.0	0.1	GO:0021794	thalamus development(GO:0021794)
0.0	0.2	GO:0046386	deoxyribose phosphate catabolic process(GO:0046386)
0.0	0.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.1	GO:0048169	regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.1	GO:0031274	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.0	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.2	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.0	GO:0042506	tyrosine phosphorylation of Stat5 protein(GO:0042506)
0.0	0.0	GO:0051905	establishment of pigment granule localization(GO:0051905)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.0	GO:0002024	diet induced thermogenesis(GO:0002024) vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0014743	regulation of cardiac muscle hypertrophy(GO:0010611) regulation of muscle hypertrophy(GO:0014743)
0.0	0.3	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	1.2	GO:0006865	amino acid transport(GO:0006865)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.3	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0031268	pseudopodium organization(GO:0031268)
0.0	0.1	GO:0042551	neuron maturation(GO:0042551)
0.0	0.2	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.8	GO:0031424	keratinization(GO:0031424)
0.0	0.0	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.5	GO:0010001	glial cell differentiation(GO:0010001)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0035313	wound healing, spreading of epidermal cells(GO:0035313) wound healing, spreading of cells(GO:0044319) epiboly(GO:0090504) epiboly involved in wound healing(GO:0090505)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0045650	negative regulation of macrophage differentiation(GO:0045650)
0.0	0.0	GO:0032274	gonadotropin secretion(GO:0032274)
0.0	0.1	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0006949	syncytium formation(GO:0006949)
0.0	0.0	GO:0000578	embryonic axis specification(GO:0000578)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0007416	synapse assembly(GO:0007416)
0.0	0.0	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.2	GO:0007128	meiotic prophase I(GO:0007128)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.1	GO:0030261	chromosome condensation(GO:0030261)
0.0	0.1	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.4	GO:0007219	Notch signaling pathway(GO:0007219)
0.0	0.0	GO:0032465	regulation of cytokinesis(GO:0032465)
0.0	0.1	GO:1901862	negative regulation of striated muscle tissue development(GO:0045843) negative regulation of muscle tissue development(GO:1901862)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.1	GO:0007405	neuroblast proliferation(GO:0007405)
0.0	0.1	GO:0007530	sex determination(GO:0007530)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.2	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0042462	photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0051546	keratinocyte migration(GO:0051546)
0.0	0.0	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0032781	positive regulation of ATPase activity(GO:0032781)
0.0	0.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0048485	sympathetic nervous system development(GO:0048485)
0.0	0.4	GO:0017148	negative regulation of translation(GO:0017148)
0.0	0.1	GO:0002088	lens development in camera-type eye(GO:0002088)
0.0	0.0	GO:0046541	saliva secretion(GO:0046541)
0.0	0.0	GO:0030539	male genitalia development(GO:0030539)
0.0	0.2	GO:0042472	inner ear morphogenesis(GO:0042472)
0.0	0.0	GO:0015837	amine transport(GO:0015837)
0.0	0.0	GO:0006760	folic acid-containing compound metabolic process(GO:0006760)
0.0	0.1	GO:0009209	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.0	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0042471	ear morphogenesis(GO:0042471)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	4.4	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.9	4.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.8	2.5	GO:0005588	collagen type V trimer(GO:0005588)
0.6	5.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.6	1.8	GO:0043259	laminin-10 complex(GO:0043259)
0.5	1.6	GO:0030934	anchoring collagen complex(GO:0030934)
0.5	1.6	GO:0070852	cell body fiber(GO:0070852)
0.5	3.6	GO:0005916	fascia adherens(GO:0005916)
0.5	1.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.5	3.4	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.4	2.1	GO:0071437	invadopodium(GO:0071437)
0.4	2.9	GO:0005614	interstitial matrix(GO:0005614)
0.4	1.1	GO:0048179	activin receptor complex(GO:0048179)
0.4	1.4	GO:0005606	laminin-1 complex(GO:0005606)
0.3	1.1	GO:0030056	hemidesmosome(GO:0030056)
0.3	0.5	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.3	1.0	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.2	1.4	GO:0010369	chromocenter(GO:0010369)
0.2	1.4	GO:0001527	microfibril(GO:0001527)
0.2	2.3	GO:0043034	costamere(GO:0043034)
0.2	1.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.2	0.9	GO:0032059	bleb(GO:0032059)
0.2	0.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.2	0.8	GO:0031430	M band(GO:0031430)
0.2	1.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	1.2	GO:0030673	axolemma(GO:0030673)
0.2	3.8	GO:0005811	lipid particle(GO:0005811)
0.2	1.6	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.2	1.0	GO:0016342	catenin complex(GO:0016342)
0.2	0.2	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.2	0.7	GO:0043205	fibril(GO:0043205)
0.2	0.9	GO:0031512	motile primary cilium(GO:0031512)
0.2	1.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.2	1.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	0.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	9.0	GO:0030426	growth cone(GO:0030426)
0.2	10.9	GO:0099572	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1	0.4	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.4	GO:0031933	telomeric heterochromatin(GO:0031933)
0.1	1.8	GO:0005581	collagen trimer(GO:0005581)
0.1	0.9	GO:0046581	intercellular canaliculus(GO:0046581)
0.1	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.1	2.1	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	1.0	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.4	GO:0033643	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	31.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.4	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.1	1.2	GO:0031941	filamentous actin(GO:0031941)
0.1	1.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.3	GO:0032444	activin responsive factor complex(GO:0032444)
0.1	0.3	GO:0071942	XPC complex(GO:0071942)
0.1	0.1	GO:0001940	male pronucleus(GO:0001940)
0.1	2.0	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.9	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	3.7	GO:0016459	myosin complex(GO:0016459)
0.1	0.5	GO:0042587	glycogen granule(GO:0042587)
0.1	0.4	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.7	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	2.2	GO:0030018	Z disc(GO:0030018)
0.1	5.5	GO:0030016	myofibril(GO:0030016)
0.1	0.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.1	2.6	GO:0034704	calcium channel complex(GO:0034704)
0.1	0.8	GO:0030658	transport vesicle membrane(GO:0030658)
0.1	0.6	GO:0030315	T-tubule(GO:0030315)
0.1	0.3	GO:0031045	dense core granule(GO:0031045)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	10.8	GO:0005911	cell-cell junction(GO:0005911)
0.1	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.3	GO:0033268	node of Ranvier(GO:0033268)
0.1	3.3	GO:0031012	extracellular matrix(GO:0031012)
0.1	0.7	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.3	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.4	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.3	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.2	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.1	GO:0070938	actomyosin contractile ring(GO:0005826) contractile ring(GO:0070938)
0.1	1.2	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	0.3	GO:0043198	dendritic shaft(GO:0043198)
0.1	0.2	GO:0042588	zymogen granule(GO:0042588)
0.1	0.6	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1	0.4	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.7	GO:0044447	axoneme part(GO:0044447)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.2	GO:0036126	outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	9.7	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	3.2	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.5	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.1	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	20.0	GO:0005615	extracellular space(GO:0005615)
0.0	0.4	GO:0032421	stereocilium bundle(GO:0032421)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0043195	terminal bouton(GO:0043195)
0.0	0.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.4	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.6	GO:0005814	centriole(GO:0005814)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.8	GO:0036064	ciliary basal body(GO:0036064)
0.0	0.4	GO:0030286	dynein complex(GO:0030286)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0000795	synaptonemal complex(GO:0000795)
0.0	1.0	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.3	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0033162	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.3	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.4	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.0	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0	0.1	GO:0046930	pore complex(GO:0046930)
0.0	2.7	GO:0045202	synapse(GO:0045202)
0.0	0.1	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0042383	sarcolemma(GO:0042383)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	7.2	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
1.1	3.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.0	3.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.8	3.3	GO:0045499	chemorepellent activity(GO:0045499)
0.8	6.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.7	2.1	GO:0070052	collagen V binding(GO:0070052)
0.7	2.1	GO:0002162	dystroglycan binding(GO:0002162)
0.6	1.9	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.6	2.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.5	2.1	GO:0050815	phosphoserine binding(GO:0050815)
0.5	1.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.5	1.5	GO:0050682	AF-2 domain binding(GO:0050682)
0.5	2.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.5	4.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.5	3.7	GO:0017166	vinculin binding(GO:0017166)
0.5	1.8	GO:0042805	actinin binding(GO:0042805)
0.4	1.3	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.4	1.7	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.4	2.9	GO:0005110	frizzled-2 binding(GO:0005110)
0.4	2.7	GO:0019966	interleukin-1 binding(GO:0019966)
0.4	2.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.4	1.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	2.8	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.3	4.5	GO:0043498	obsolete cell surface binding(GO:0043498)
0.3	1.0	GO:0003680	AT DNA binding(GO:0003680)
0.3	7.7	GO:0050840	extracellular matrix binding(GO:0050840)
0.3	0.9	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.3	1.2	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	1.2	GO:0030172	troponin C binding(GO:0030172)
0.3	1.2	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.3	0.9	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3	0.9	GO:0042577	lipid phosphatase activity(GO:0042577)
0.3	1.1	GO:0004470	malic enzyme activity(GO:0004470)
0.3	0.8	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.3	1.9	GO:0042043	neurexin family protein binding(GO:0042043)
0.3	0.8	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3	1.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.3	0.8	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.3	0.8	GO:0035198	miRNA binding(GO:0035198)
0.2	4.5	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	1.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2	2.4	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.2	2.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.2	0.7	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	1.9	GO:0030544	Hsp70 protein binding(GO:0030544)
0.2	1.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.2	0.9	GO:0019211	phosphatase activator activity(GO:0019211)
0.2	2.5	GO:0005523	tropomyosin binding(GO:0005523)
0.2	0.9	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.2	1.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.2	1.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.2	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.2	0.9	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.2	0.6	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.2	1.0	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.2	0.6	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.2	0.6	GO:0004995	tachykinin receptor activity(GO:0004995)
0.2	14.0	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.2	2.2	GO:0070064	proline-rich region binding(GO:0070064)
0.2	0.6	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.2	0.6	GO:0004948	calcitonin receptor activity(GO:0004948)
0.2	2.3	GO:0005243	gap junction channel activity(GO:0005243)
0.2	0.8	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.2	0.6	GO:0045545	syndecan binding(GO:0045545)
0.2	1.1	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.2	0.9	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.2	0.5	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.2	1.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.2	0.7	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	1.4	GO:0001968	fibronectin binding(GO:0001968)
0.2	0.5	GO:0001601	peptide YY receptor activity(GO:0001601)
0.2	0.5	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.2	0.8	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.2	0.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2	0.5	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2	0.5	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	0.7	GO:0016934	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.2	1.7	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	0.7	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.6	GO:0008179	adenylate cyclase binding(GO:0008179)
0.2	1.1	GO:0000339	RNA cap binding(GO:0000339)
0.2	1.3	GO:0016595	glutamate binding(GO:0016595)
0.2	0.5	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	0.5	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.2	0.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2	0.8	GO:0043522	leucine zipper domain binding(GO:0043522)
0.2	0.6	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.2	0.3	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.7	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.6	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.4	GO:0035254	glutamate receptor binding(GO:0035254)
0.1	0.7	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.9	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1	1.4	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.6	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.4	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1	1.0	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	5.2	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	0.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	1.0	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.1	0.4	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.6	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	1.9	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.9	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	0.8	GO:0048185	activin binding(GO:0048185)
0.1	0.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.8	GO:0050811	GABA receptor binding(GO:0050811)
0.1	0.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.8	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.4	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1	1.0	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.1	0.4	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.5	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.1	1.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.3	GO:0031177	phosphopantetheine binding(GO:0031177)
0.1	0.4	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.7	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.9	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	1.2	GO:0045296	cadherin binding(GO:0045296)
0.1	0.5	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.1	0.8	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	1.0	GO:0030553	cGMP binding(GO:0030553)
0.1	1.7	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.5	GO:0005499	vitamin D binding(GO:0005499)
0.1	3.0	GO:0051015	actin filament binding(GO:0051015)
0.1	0.4	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	3.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.1	0.5	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.5	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.1	0.5	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	1.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.3	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.9	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	0.2	GO:0034711	inhibin binding(GO:0034711)
0.1	0.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	1.3	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.3	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.2	GO:0051380	norepinephrine binding(GO:0051380)
0.1	1.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	0.3	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.6	GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1	0.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.1	0.2	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.7	GO:0051378	serotonin binding(GO:0051378)
0.1	0.9	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	1.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1	0.9	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.1	2.0	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.1	0.5	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.1	0.4	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1	1.5	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1	0.4	GO:0005000	vasopressin receptor activity(GO:0005000)
0.1	0.4	GO:0043394	proteoglycan binding(GO:0043394)
0.1	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.1	1.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.7	GO:0005123	death receptor binding(GO:0005123)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.4	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.3	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.2	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.1	1.0	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.5	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	0.5	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.1	0.2	GO:0008502	melatonin receptor activity(GO:0008502)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.1	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.1	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	3.8	GO:0008201	heparin binding(GO:0008201)
0.1	0.2	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.3	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.1	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.6	GO:0004407	histone deacetylase activity(GO:0004407)
0.1	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.2	GO:0008518	reduced folate carrier activity(GO:0008518)
0.1	0.6	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	6.5	GO:0008083	growth factor activity(GO:0008083)
0.1	0.8	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.2	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.9	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	0.2	GO:0019863	IgE binding(GO:0019863)
0.1	0.4	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.4	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	12.7	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.0	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.6	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.2	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.2	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.2	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.5	GO:0005355	glucose transmembrane transporter activity(GO:0005355)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	1.4	GO:0019825	oxygen binding(GO:0019825)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.3	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.5	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.2	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.3	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	1.1	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	2.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.4	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	2.7	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.2	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.2	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0022824	transmitter-gated ion channel activity(GO:0022824) transmitter-gated channel activity(GO:0022835)
0.0	3.1	GO:0003774	motor activity(GO:0003774)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	1.6	GO:0005179	hormone activity(GO:0005179)
0.0	0.2	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.2	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.2	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	9.8	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.1	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.1	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0043121	neurotrophin binding(GO:0043121) nerve growth factor binding(GO:0048406)
0.0	0.5	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	1.9	GO:0008236	serine-type peptidase activity(GO:0008236)
0.0	1.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.0	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0052743	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659) inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.0	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0003730	mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	0.7	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	14.8	NABA COLLAGENS	Genes encoding collagen proteins
0.2	2.0	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	8.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	2.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.2	5.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.2	2.1	PID ALK2 PATHWAY	ALK2 signaling events
0.2	4.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.2	2.5	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	0.6	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	0.4	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	1.0	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	5.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	3.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	1.0	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	0.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	0.2	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	15.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	0.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.1	3.2	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	2.9	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.1	2.7	PID BMP PATHWAY	BMP receptor signaling
0.1	2.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	1.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	1.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.4	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	2.3	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	2.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.0	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	0.8	PID ALK1 PATHWAY	ALK1 signaling events
0.1	0.7	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	12.5	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.1	0.1	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	2.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.9	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.7	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.7	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events
0.0	5.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	0.3	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	8.2	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.2	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	PID S1P S1P2 PATHWAY	S1P2 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	7.9	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.5	0.5	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.4	12.0	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.4	5.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.4	3.9	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.3	1.9	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	6.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.3	15.3	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	0.3	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.2	3.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	2.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	1.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.2	2.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	2.1	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	3.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	1.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	4.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	0.6	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.2	3.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.2	2.5	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.2	0.3	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.2	2.0	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	3.9	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.2	0.2	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	1.8	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.2	2.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.1	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.1	2.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	2.6	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.1	2.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	2.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.1	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.1	1.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.8	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.0	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	0.6	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.1	1.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.5	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.1	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	0.9	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	2.2	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.1	0.9	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.1	0.7	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.1	1.5	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.7	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1	0.3	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	1.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	0.6	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1	1.9	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	0.4	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	0.6	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.7	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.1	REACTOME FRS2 MEDIATED CASCADE	Genes involved in FRS2-mediated cascade
0.0	1.1	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.7	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.2	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.7	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.4	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.5	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.2	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.3	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.4	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.2	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.0	0.3	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.0	0.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.2	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	0.3	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.3	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	1.0	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME TELOMERE MAINTENANCE	Genes involved in Telomere Maintenance
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.4	REACTOME ION CHANNEL TRANSPORT	Genes involved in Ion channel transport
0.0	0.2	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA

Results for HOXC8

Z-value: 3.86

Motif logo

Transcription factors associated with HOXC8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXC8 motif across conditions

Conditions sorted by the z-value of the HOXC8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXC8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: