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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXD10

Z-value: 2.39

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Transcription factors associated with HOXD10

Gene Symbol	Gene ID	Gene Info
HOXD10 Ensembl NCBI GeneCards UniProt	ENSG00000128710.5	homeobox D10

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_176981076_176981274	HOXD10	132	0.894553	0.78	1.2e-02	Click!
chr2_176981554_176981705	HOXD10	322	0.731880	0.44	2.3e-01	Click!
chr2_176982170_176982321	HOXD10	938	0.307652	0.44	2.3e-01	Click!
chr2_176981739_176981890	HOXD10	507	0.559838	0.25	5.2e-01	Click!
chr2_176983652_176983803	HOXD10	2420	0.114138	0.23	5.4e-01	Click!

Activity of the HOXD10 motif across conditions

Conditions sorted by the z-value of the HOXD10 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr22_46477864_46478136	2.00	FLJ27365	hsa-mir-4763	1808	0.2
chr5_54456050_54456451	1.63	GPX8	glutathione peroxidase 8 (putative)	252	0.86
chr11_121968787_121969071	1.40	ENSG00000207971	.	1623	0.3
chr22_46462951_46463814	1.18	RP6-109B7.4		2389	0.16
chr3_114169976_114170457	1.13	ZBTB20	zinc finger and BTB domain containing 20	3314	0.33
chr5_66254399_66254664	1.02	MAST4	microtubule associated serine/threonine kinase family member 4	167	0.97
chr4_152146952_152147499	1.00	SH3D19	SH3 domain containing 19	7	0.98
chr2_197852125_197852688	0.98	ANKRD44	ankyrin repeat domain 44	12820	0.25
chr4_148944622_148945028	0.98	RP11-76G10.1		122797	0.06
chr12_78334342_78334902	0.94	NAV3	neuron navigator 3	25434	0.27
chr3_55520023_55520469	0.92	WNT5A	wingless-type MMTV integration site family, member 5A	1085	0.48
chr10_70321971_70322188	0.91	TET1	tet methylcytosine dioxygenase 1	1666	0.36
chr11_69454506_69454752	0.91	CCND1	cyclin D1	1226	0.52
chr22_36232318_36232521	0.87	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	3846	0.33
chr6_44424385_44424803	0.86	ENSG00000266619	.	21216	0.17
chr9_14312608_14313176	0.85	NFIB	nuclear factor I/B	774	0.71
chr6_169652381_169652976	0.81	THBS2	thrombospondin 2	432	0.89
chr12_59311038_59311457	0.79	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2080	0.36
chr3_150089259_150089633	0.78	TSC22D2	TSC22 domain family, member 2	36676	0.21
chr9_21688149_21688723	0.78	ENSG00000244230	.	10877	0.24
chr7_116312981_116313724	0.78	MET	met proto-oncogene	893	0.68
chr7_114055343_114055580	0.77	FOXP2	forkhead box P2	83	0.98
chr15_93615075_93616283	0.76	RGMA	repulsive guidance molecule family member a	695	0.78
chr3_33318777_33319866	0.74	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr11_121968562_121968780	0.74	ENSG00000207971	.	1881	0.27
chr3_175244326_175245006	0.73	ENSG00000201648	.	82601	0.1
chr1_95330057_95330663	0.71	SLC44A3	solute carrier family 44, member 3	2527	0.28
chr4_86700210_86700446	0.71	ARHGAP24	Rho GTPase activating protein 24	469	0.88
chr15_30112674_30113382	0.71	TJP1	tight junction protein 1	723	0.64
chr4_54063057_54063462	0.69	ENSG00000207385	.	68475	0.13
chr11_94528525_94528870	0.69	AMOTL1	angiomotin like 1	27160	0.2
chr2_157749235_157750071	0.69	ENSG00000263848	.	122116	0.06
chr6_166259879_166260251	0.68	SDIM1	stress responsive DNAJB4 interacting membrane protein 1	49660	0.16
chr8_141733894_141734187	0.68	PTK2	protein tyrosine kinase 2	2153	0.35
chr1_215180647_215181021	0.68	KCNK2	potassium channel, subfamily K, member 2	1636	0.56
chr8_42063953_42065062	0.68	PLAT	plasminogen activator, tissue	576	0.71
chr15_96884556_96884898	0.67	ENSG00000222651	.	8237	0.16
chr15_35959426_35959743	0.64	DPH6	diphthamine biosynthesis 6	121191	0.07
chr7_114055046_114055222	0.63	FOXP2	forkhead box P2	21	0.98
chr9_22008020_22008450	0.63	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	717	0.61
chr1_185704392_185704588	0.63	HMCN1	hemicentin 1	807	0.75
chr15_99788624_99789059	0.63	TTC23	tetratricopeptide repeat domain 23	895	0.51
chr1_57041430_57041821	0.63	PPAP2B	phosphatidic acid phosphatase type 2B	3616	0.34
chr6_169653692_169653887	0.62	THBS2	thrombospondin 2	350	0.92
chr6_19691587_19692480	0.62	ENSG00000200957	.	49273	0.18
chr11_36252522_36252860	0.62	COMMD9	COMM domain containing 9	58283	0.13
chr1_240250348_240250507	0.62	FMN2	formin 2	4753	0.3
chr1_179111271_179111703	0.62	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr1_79043181_79043547	0.62	IFI44L	interferon-induced protein 44-like	42243	0.17
chr8_89311514_89311910	0.61	RP11-586K2.1		27353	0.2
chr5_142623144_142623555	0.61	ARHGAP26	Rho GTPase activating protein 26	36584	0.19
chr3_98700853_98701271	0.61	ENSG00000207331	.	73759	0.1
chr12_91504103_91504272	0.61	LUM	lumican	1421	0.48
chr3_104078695_104079148	0.59	ENSG00000265076	.	305281	0.01
chr8_60538222_60538702	0.59	ENSG00000201763	.	170018	0.04
chr3_29327656_29328192	0.59	RBMS3-AS3	RBMS3 antisense RNA 3	4293	0.26
chr15_96882948_96883133	0.59	ENSG00000222651	.	6550	0.16
chr5_32027565_32028229	0.59	ENSG00000266243	.	91632	0.07
chr2_164592268_164592669	0.58	FIGN	fidgetin	49	0.99
chr5_167000633_167001353	0.58	CTB-78F1.1		86493	0.1
chr7_94026049_94026200	0.57	COL1A2	collagen, type I, alpha 2	2251	0.42
chr7_134464463_134465343	0.57	CALD1	caldesmon 1	474	0.89
chr6_152085810_152086045	0.57	ESR1	estrogen receptor 1	39639	0.18
chr3_150064794_150064984	0.57	TSC22D2	TSC22 domain family, member 2	61233	0.14
chr3_100785098_100785499	0.57	ABI3BP	ABI family, member 3 (NESH) binding protein	72939	0.11
chr4_81195528_81195918	0.57	FGF5	fibroblast growth factor 5	7930	0.26
chr9_137535305_137535456	0.55	COL5A1	collagen, type V, alpha 1	1760	0.38
chr4_160169630_160170007	0.55	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	18215	0.23
chr10_76684287_76684702	0.55	KAT6B	K(lysine) acetyltransferase 6B	86036	0.08
chr14_71022448_71023169	0.55	ADAM20	ADAM metallopeptidase domain 20	21076	0.17
chr2_190272115_190272296	0.55	WDR75	WD repeat domain 75	33954	0.2
chr7_134465998_134466492	0.55	CALD1	caldesmon 1	1816	0.49
chr19_47735595_47736220	0.55	BBC3	BCL2 binding component 3	116	0.95
chr7_83822850_83823057	0.54	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	1264	0.65
chr22_36232996_36233711	0.54	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2912	0.37
chr3_21736170_21736448	0.54	ZNF385D	zinc finger protein 385D	56618	0.16
chr20_6764834_6765429	0.54	BMP2	bone morphogenetic protein 2	16820	0.28
chr9_89738235_89738413	0.53	C9orf170	chromosome 9 open reading frame 170	25235	0.26
chr4_121990444_121990801	0.53	NDNF	neuron-derived neurotrophic factor	2534	0.31
chr18_74798828_74799607	0.53	MBP	myelin basic protein	18000	0.27
chr6_3473109_3473260	0.53	SLC22A23	solute carrier family 22, member 23	15928	0.27
chr5_39423074_39423254	0.53	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	1806	0.48
chr4_159093168_159093728	0.53	RP11-597D13.9		281	0.64
chr1_99729766_99730318	0.52	LPPR4	Lipid phosphate phosphatase-related protein type 4	194	0.97
chr18_30310087_30311054	0.52	AC012123.1	Uncharacterized protein	39188	0.17
chr1_8433877_8434267	0.52	RERE	arginine-glutamic acid dipeptide (RE) repeats	9174	0.19
chr3_114477857_114478359	0.52	ZBTB20	zinc finger and BTB domain containing 20	10	0.99
chr11_503866_504897	0.51	RNH1	ribonuclease/angiogenin inhibitor 1	171	0.89
chr4_152148504_152148764	0.51	SH3D19	SH3 domain containing 19	548	0.8
chr12_21927918_21928225	0.51	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8	316	0.88
chr11_12454847_12455344	0.51	PARVA	parvin, alpha	19187	0.24
chr18_59067267_59067515	0.51	ENSG00000206769	.	8563	0.3
chr2_152214605_152215087	0.51	TNFAIP6	tumor necrosis factor, alpha-induced protein 6	740	0.63
chr17_79315981_79316442	0.50	TMEM105	transmembrane protein 105	11737	0.13
chr13_99629621_99629906	0.50	DOCK9	dedicator of cytokinesis 9	481	0.85
chr9_80437599_80437890	0.50	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	171	0.98
chr21_30673835_30674113	0.50	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	851	0.62
chr2_188418224_188418410	0.50	AC007319.1		559	0.57
chr7_94027821_94027972	0.50	COL1A2	collagen, type I, alpha 2	4023	0.33
chr4_187648403_187648661	0.50	FAT1	FAT atypical cadherin 1	656	0.82
chr6_152701109_152701260	0.50	SYNE1-AS1	SYNE1 antisense RNA 1	497	0.78
chr13_39992060_39992261	0.49	ENSG00000238408	.	29193	0.25
chr10_24755480_24755818	0.49	KIAA1217	KIAA1217	189	0.96
chr1_25895160_25895475	0.49	LDLRAP1	low density lipoprotein receptor adaptor protein 1	25246	0.17
chr11_121970307_121971111	0.49	ENSG00000207971	.	157	0.79
chr8_142048186_142048475	0.49	PTK2	protein tyrosine kinase 2	36121	0.17
chr3_190530283_190530682	0.49	GMNC	geminin coiled-coil domain containing	49922	0.18
chr3_149339263_149339595	0.49	WWTR1-IT1	WWTR1 intronic transcript 1 (non-protein coding)	28542	0.15
chr10_32438008_32438363	0.49	ENSG00000252482	.	24427	0.2
chr4_157700840_157701063	0.49	RP11-154F14.2		61560	0.13
chr22_40707066_40707217	0.48	ADSL	adenylosuccinate lyase	35366	0.15
chr22_40706773_40706982	0.48	ADSL	adenylosuccinate lyase	35630	0.14
chr12_76653631_76654077	0.48	ENSG00000223273	.	55677	0.14
chr18_53178087_53178424	0.48	TCF4	transcription factor 4	255	0.93
chr5_39418140_39418360	0.48	DAB2	Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)	6720	0.29
chr13_36343879_36344030	0.48	DCLK1	doublecortin-like kinase 1	85825	0.1
chr8_122515112_122515274	0.48	ENSG00000263525	.	40042	0.21
chr7_94026391_94026542	0.48	COL1A2	collagen, type I, alpha 2	2593	0.39
chr3_149801405_149801614	0.48	ENSG00000243321	.	5891	0.21
chr12_59434723_59435248	0.48	RP11-150C16.1		120565	0.06
chr7_116170513_116170982	0.47	CAV1	caveolin 1, caveolae protein, 22kDa	4400	0.18
chr1_1676260_1677404	0.47	SLC35E2	solute carrier family 35, member E2	526	0.68
chr5_141980216_141980760	0.47	AC005592.2		19075	0.18
chr1_196527542_196527719	0.47	ENSG00000265986	.	23981	0.22
chr6_132437274_132437503	0.47	ENSG00000265669	.	985	0.69
chr1_216704476_216705111	0.47	USH2A	Usher syndrome 2A (autosomal recessive, mild)	108055	0.08
chr5_35309735_35309886	0.46	PRLR	prolactin receptor	79016	0.1
chr5_78985270_78986298	0.46	CMYA5	cardiomyopathy associated 5	84	0.98
chr6_45523951_45524153	0.46	ENSG00000252738	.	89789	0.09
chr12_76422565_76423423	0.46	RP11-290L1.3		1280	0.41
chr3_79023077_79023270	0.46	ENSG00000240964	.	35731	0.2
chr5_102202832_102203172	0.46	PAM	peptidylglycine alpha-amidating monooxygenase	1182	0.66
chr6_11795100_11795449	0.46	ADTRP	androgen-dependent TFPI-regulating protein	12005	0.28
chr8_32506055_32506353	0.46	NRG1	neuregulin 1	847	0.76
chr3_89074301_89074693	0.46	EPHA3	EPH receptor A3	82177	0.12
chr13_24044512_24044663	0.46	SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	36746	0.21
chr21_28215844_28216573	0.45	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	112	0.98
chr3_114168204_114168554	0.45	ZBTB20	zinc finger and BTB domain containing 20	5151	0.29
chr6_12427440_12427701	0.45	ENSG00000223321	.	20557	0.28
chr15_59622162_59622355	0.45	ENSG00000199512	.	11358	0.14
chr3_109884338_109884502	0.45	ENSG00000221206	.	386392	0.01
chr7_19155354_19155672	0.45	TWIST1	twist family bHLH transcription factor 1	1782	0.28
chr9_684288_685148	0.45	RP11-130C19.3		837	0.67
chr9_21677527_21678485	0.45	ENSG00000244230	.	21307	0.21
chr2_202904203_202904368	0.45	FZD7	frizzled family receptor 7	4975	0.19
chr1_196622943_196623164	0.45	CFH	complement factor H	1867	0.41
chr6_48078606_48078757	0.45	PTCHD4	patched domain containing 4	42256	0.22
chr8_62686205_62686405	0.45	ENSG00000264408	.	58958	0.14
chr1_185688405_185688780	0.45	HMCN1	hemicentin 1	15091	0.26
chr6_85484117_85484534	0.45	TBX18	T-box 18	10088	0.3
chr14_62230360_62230511	0.45	SNAPC1	small nuclear RNA activating complex, polypeptide 1, 43kDa	1360	0.55
chr8_79468522_79468695	0.45	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha	34858	0.19
chr18_52626293_52626952	0.45	CCDC68	coiled-coil domain containing 68	117	0.97
chr12_29744562_29745018	0.44	TMTC1	transmembrane and tetratricopeptide repeat containing 1	12367	0.26
chr18_18775376_18775547	0.44	GREB1L	growth regulation by estrogen in breast cancer-like	46742	0.15
chr1_179096167_179096689	0.44	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	15751	0.19
chr11_85961580_85961731	0.44	EED	embryonic ectoderm development	5379	0.24
chr10_29922441_29923089	0.44	SVIL	supervillin	1136	0.54
chr3_93878024_93878443	0.44	ENSG00000253062	.	60823	0.12
chr4_114679395_114679686	0.44	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	2684	0.42
chr1_236073367_236073780	0.44	ENSG00000206803	.	5142	0.2
chr11_44383183_44383459	0.44	ALX4	ALX homeobox 4	51605	0.17
chr11_114033998_114034413	0.44	ENSG00000221112	.	76554	0.09
chr22_36310772_36312004	0.44	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	23557	0.25
chr5_31806865_31807016	0.43	PDZD2	PDZ domain containing 2	7909	0.14
chr11_94529113_94529270	0.43	AMOTL1	angiomotin like 1	27654	0.2
chr14_71255809_71256187	0.43	MAP3K9	mitogen-activated protein kinase kinase kinase 9	5836	0.3
chr6_125550220_125550378	0.43	TPD52L1	tumor protein D52-like 1	9308	0.28
chr3_29964845_29964996	0.43	RBMS3-AS1	RBMS3 antisense RNA 1	10727	0.31
chr4_41157110_41157449	0.43	ENSG00000207198	.	41320	0.14
chr4_170189368_170189538	0.43	SH3RF1	SH3 domain containing ring finger 1	1655	0.5
chr10_4719979_4720356	0.43	AKR1E2	aldo-keto reductase family 1, member E2	108654	0.07
chr8_106645652_106645917	0.43	RP11-642D21.1		36435	0.19
chr5_124071713_124071892	0.43	RP11-436H11.5		934	0.37
chr5_119802087_119802238	0.43	PRR16	proline rich 16	836	0.77
chr6_152792590_152792847	0.42	SYNE1	spectrin repeat containing, nuclear envelope 1	1047	0.59
chr1_94711175_94711488	0.42	ARHGAP29	Rho GTPase activating protein 29	8142	0.25
chr1_215742028_215742345	0.42	KCTD3	potassium channel tetramerization domain containing 3	1451	0.56
chr8_25864992_25865143	0.42	EBF2	early B-cell factor 2	33937	0.23
chr2_20261222_20261477	0.42	RP11-644K8.1		9454	0.17
chr4_153270968_153271263	0.42	FBXW7	F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase	1157	0.54
chr5_61389218_61389599	0.42	ENSG00000251983	.	53084	0.18
chr15_96881380_96881711	0.42	ENSG00000222651	.	5055	0.17
chr2_230845561_230845747	0.42	ENSG00000206725	.	7623	0.17
chr18_46472333_46472626	0.42	SMAD7	SMAD family member 7	2396	0.36
chr6_85470567_85470756	0.42	TBX18	T-box 18	2412	0.42
chr12_64581322_64581595	0.42	ENSG00000212298	.	17115	0.15
chr4_86749229_86749793	0.42	ARHGAP24	Rho GTPase activating protein 24	465	0.88
chr1_218672576_218672996	0.42	C1orf143	chromosome 1 open reading frame 143	10652	0.26
chr18_10058041_10058330	0.42	ENSG00000263630	.	52991	0.15
chr12_8814882_8815352	0.41	MFAP5	microfibrillar associated protein 5	98	0.95
chr12_63025061_63025357	0.41	ENSG00000238475	.	19746	0.14
chr11_89113858_89114276	0.41	NOX4	NADPH oxidase 4	109833	0.07
chr4_148009583_148009791	0.41	TTC29	tetratricopeptide repeat domain 29	142653	0.05
chr10_4358088_4358256	0.41	ENSG00000207124	.	198972	0.03
chr15_60684685_60685107	0.41	ANXA2	annexin A2	1400	0.54
chr5_72417110_72417261	0.41	TMEM171	transmembrane protein 171	789	0.61
chr7_42355171_42355392	0.41	GLI3	GLI family zinc finger 3	78623	0.12
chr4_119962368_119962530	0.41	SYNPO2	synaptopodin 2	17823	0.26
chr7_151433344_151433930	0.41	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	237	0.95

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.8	GO:0031223	auditory behavior(GO:0031223)
0.5	2.1	GO:0043589	skin morphogenesis(GO:0043589)
0.5	2.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5	1.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4	1.3	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.4	1.6	GO:0070141	response to UV-A(GO:0070141)
0.4	1.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.3	1.0	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.3	1.3	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.3	1.1	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.3	1.0	GO:0010664	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3	1.0	GO:0008218	bioluminescence(GO:0008218)
0.3	0.8	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.3	0.8	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.3	1.3	GO:0048875	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.3	0.8	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	0.5	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	1.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	0.5	GO:0060068	vagina development(GO:0060068)
0.2	0.5	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.2	0.7	GO:0071694	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.6	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2	0.4	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	0.6	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.2	1.6	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2	0.8	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.2	0.2	GO:0090103	cochlea morphogenesis(GO:0090103)
0.2	0.4	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	0.4	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2	0.4	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2	0.6	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.2	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.7	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	0.7	GO:0010107	potassium ion import(GO:0010107)
0.2	0.9	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	0.5	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2	0.5	GO:0060437	lung growth(GO:0060437)
0.2	0.5	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.2	0.5	GO:0022605	oogenesis stage(GO:0022605)
0.2	0.2	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.2	0.2	GO:0051584	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.2	1.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.5	GO:1903332	regulation of protein folding(GO:1903332)
0.2	0.5	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	1.1	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.1	0.3	GO:0010193	response to ozone(GO:0010193)
0.1	1.3	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.1	GO:0043301	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1	0.7	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.7	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.1	0.3	GO:1903053	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	1.5	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.4	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.4	GO:0032808	lacrimal gland development(GO:0032808)
0.1	0.5	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1	0.4	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.3	GO:0051834	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.1	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	1.2	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1	0.6	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.2	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.5	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.6	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.8	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.7	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.5	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.6	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.3	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.1	0.9	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.1	0.8	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.4	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.1	GO:0060435	bronchiole development(GO:0060435)
0.1	0.7	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.1	GO:0060535	trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1	0.2	GO:0048845	venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.1	0.3	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.2	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.1	0.4	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.2	GO:0060242	contact inhibition(GO:0060242)
0.1	0.5	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.1	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	1.7	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.1	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.5	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.1	0.2	GO:0051014	actin filament severing(GO:0051014)
0.1	0.3	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.3	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.1	0.3	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	1.4	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.1	0.4	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	0.4	GO:0007619	courtship behavior(GO:0007619)
0.1	0.3	GO:0060013	righting reflex(GO:0060013)
0.1	0.2	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1	0.2	GO:0060438	trachea development(GO:0060438)
0.1	0.7	GO:0030238	male sex determination(GO:0030238)
0.1	0.3	GO:0021978	telencephalon regionalization(GO:0021978)
0.1	0.2	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.3	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1	0.4	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	1.9	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	1.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.5	GO:0007530	sex determination(GO:0007530)
0.1	0.8	GO:0008347	glial cell migration(GO:0008347)
0.1	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.1	GO:0022038	corpus callosum development(GO:0022038)
0.1	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.1	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.3	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.1	0.4	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.7	GO:0030325	adrenal gland development(GO:0030325)
0.1	0.1	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1	0.2	GO:0010799	regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1	0.3	GO:0016322	neuron remodeling(GO:0016322)
0.1	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	0.3	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	2.1	GO:0060606	neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1	0.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	0.5	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.3	GO:0015871	choline transport(GO:0015871)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.1	GO:1903170	negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.3	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.1	0.3	GO:0080111	DNA demethylation(GO:0080111)
0.1	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.6	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.3	GO:0001660	fever generation(GO:0001660)
0.1	0.2	GO:0034105	positive regulation of tissue remodeling(GO:0034105)
0.1	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	0.4	GO:0007413	axonal fasciculation(GO:0007413)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.5	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.1	GO:0021794	thalamus development(GO:0021794)
0.1	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.1	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.1	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.2	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.1	0.2	GO:0032836	glomerular basement membrane development(GO:0032836)
0.1	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.1	0.2	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.1	0.5	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0055057	neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.2	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.1	0.2	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.1	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.5	GO:0006949	syncytium formation(GO:0006949)
0.1	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1	0.2	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.2	GO:0009822	alkaloid catabolic process(GO:0009822)
0.1	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.1	0.2	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.1	0.1	GO:0031639	plasminogen activation(GO:0031639)
0.1	0.1	GO:0042640	anagen(GO:0042640)
0.1	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.2	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.1	0.7	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.1	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	0.2	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	0.9	GO:0007566	embryo implantation(GO:0007566)
0.1	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.4	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.4	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.3	GO:0006477	protein sulfation(GO:0006477)
0.0	0.8	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.5	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.2	GO:0001759	organ induction(GO:0001759)
0.0	0.1	GO:0010656	negative regulation of muscle cell apoptotic process(GO:0010656)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0019098	reproductive behavior(GO:0019098)
0.0	0.4	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.2	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.0	0.1	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.0	0.0	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.2	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	1.0	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.1	GO:0071800	podosome assembly(GO:0071800)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.3	GO:0007494	midgut development(GO:0007494)
0.0	0.2	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611)
0.0	0.2	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.7	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.3	GO:0001508	action potential(GO:0001508)
0.0	0.2	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.0	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0	4.4	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	1.4	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.4	GO:0030901	midbrain development(GO:0030901)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0072193	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0045657	positive regulation of monocyte differentiation(GO:0045657)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0060442	branching involved in prostate gland morphogenesis(GO:0060442)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.0	GO:0034445	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.2	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0001757	somite specification(GO:0001757)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0	0.4	GO:0042730	fibrinolysis(GO:0042730)
0.0	0.3	GO:0042522	regulation of tyrosine phosphorylation of Stat5 protein(GO:0042522)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.4	GO:0014075	response to amine(GO:0014075)
0.0	0.1	GO:0015820	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0010829	negative regulation of glucose transport(GO:0010829)
0.0	0.1	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0	0.1	GO:0009111	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.4	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.2	GO:0071385	cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.5	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0055008	cardiac muscle tissue morphogenesis(GO:0055008)
0.0	0.1	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:0014044	Schwann cell development(GO:0014044)
0.0	0.2	GO:0030299	intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.0	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0	0.0	GO:0070528	protein kinase C signaling(GO:0070528)
0.0	0.0	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.1	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0060581	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.0	GO:0051590	positive regulation of neurotransmitter transport(GO:0051590)
0.0	0.1	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.0	0.0	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.6	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.0	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.3	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.0	GO:0051898	negative regulation of protein kinase B signaling(GO:0051898)
0.0	0.4	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.1	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.0	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0097576	vacuole fusion(GO:0097576)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	2.6	GO:0006936	muscle contraction(GO:0006936)
0.0	0.3	GO:0007043	cell-cell junction assembly(GO:0007043)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.0	GO:0003208	cardiac ventricle morphogenesis(GO:0003208)
0.0	0.1	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.0	GO:0000212	meiotic spindle organization(GO:0000212)
0.0	0.3	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0	0.0	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0060046	regulation of acrosome reaction(GO:0060046)
0.0	0.1	GO:0035115	embryonic forelimb morphogenesis(GO:0035115)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.0	0.0	GO:0060157	urinary bladder development(GO:0060157)
0.0	0.0	GO:0034331	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0	0.0	GO:0070253	somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0	0.0	GO:0022010	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0	0.1	GO:0009208	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.0	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.0	GO:0048853	forebrain morphogenesis(GO:0048853)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.0	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0019369	arachidonic acid metabolic process(GO:0019369)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.0	0.0	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.2	GO:0007492	endoderm development(GO:0007492)
0.0	0.0	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.0	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.0	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.0	GO:0032100	positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) GTP metabolic process(GO:0046039) prosthetic group metabolic process(GO:0051189)
0.0	0.2	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.2	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.0	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.0	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0006734	NADH metabolic process(GO:0006734)
0.0	0.0	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:0032095	regulation of response to food(GO:0032095)
0.0	0.0	GO:0021754	facial nucleus development(GO:0021754)
0.0	0.1	GO:0051897	positive regulation of protein kinase B signaling(GO:0051897)
0.0	0.0	GO:0043587	tongue morphogenesis(GO:0043587)
0.0	0.1	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0015695	organic cation transport(GO:0015695)
0.0	0.1	GO:0044245	polysaccharide digestion(GO:0044245)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.0	GO:0003321	positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0	0.1	GO:0007613	memory(GO:0007613)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.0	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.0	0.0	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.1	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0005589	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	1.7	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	3.4	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3	1.0	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.7	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.4	GO:0098642	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2	0.5	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	1.4	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.5	GO:0043259	laminin-10 complex(GO:0043259)
0.2	0.8	GO:0071437	invadopodium(GO:0071437)
0.2	1.3	GO:0030128	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1	0.6	GO:0005606	laminin-1 complex(GO:0005606)
0.1	0.4	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.6	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0016342	catenin complex(GO:0016342)
0.1	0.7	GO:0001527	microfibril(GO:0001527)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.5	GO:0016012	sarcoglycan complex(GO:0016012)
0.1	0.5	GO:0005916	fascia adherens(GO:0005916)
0.1	1.4	GO:0009925	basal plasma membrane(GO:0009925)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	1.0	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	2.0	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.2	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.7	GO:0030315	T-tubule(GO:0030315)
0.1	1.1	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	3.4	GO:0005604	basement membrane(GO:0005604)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	0.2	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.1	0.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.1	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	1.0	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	0.3	GO:0005581	collagen trimer(GO:0005581)
0.1	0.4	GO:0031258	lamellipodium membrane(GO:0031258)
0.1	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.1	4.9	GO:0030016	myofibril(GO:0030016)
0.0	0.0	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	2.5	GO:0030426	growth cone(GO:0030426)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	8.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0098878	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	1.1	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	1.8	GO:0031012	extracellular matrix(GO:0031012)
0.0	2.3	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.5	GO:0005811	lipid particle(GO:0005811)
0.0	2.2	GO:0043296	apical junction complex(GO:0043296)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	2.5	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.7	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	2.2	GO:0034705	potassium channel complex(GO:0034705)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.2	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.0	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.0	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.0	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.0	GO:0071547	piP-body(GO:0071547)
0.0	0.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	2.6	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.4	1.3	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	1.0	GO:0042577	lipid phosphatase activity(GO:0042577)
0.3	1.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.3	1.0	GO:0030215	semaphorin receptor binding(GO:0030215)
0.3	0.9	GO:0050682	AF-2 domain binding(GO:0050682)
0.3	1.2	GO:0045499	chemorepellent activity(GO:0045499)
0.3	0.8	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.3	0.8	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.3	0.8	GO:0002162	dystroglycan binding(GO:0002162)
0.2	2.7	GO:0070064	proline-rich region binding(GO:0070064)
0.2	0.6	GO:0016842	amidine-lyase activity(GO:0016842)
0.2	0.6	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2	1.6	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2	2.7	GO:0005523	tropomyosin binding(GO:0005523)
0.2	1.5	GO:0017166	vinculin binding(GO:0017166)
0.2	2.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.8	GO:0017154	semaphorin receptor activity(GO:0017154)
0.2	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	1.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.1	0.4	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	0.4	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.7	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.4	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.4	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.4	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.9	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.5	GO:0048495	Roundabout binding(GO:0048495)
0.1	0.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.6	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	1.7	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	2.1	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.6	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	4.3	GO:0005518	collagen binding(GO:0005518)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.4	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	1.0	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.5	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.5	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.8	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.4	GO:0042805	actinin binding(GO:0042805)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.1	0.3	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.3	GO:0035198	miRNA binding(GO:0035198)
0.1	0.3	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.3	GO:0045545	syndecan binding(GO:0045545)
0.1	0.9	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	0.2	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.4	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.2	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.1	0.5	GO:0048185	activin binding(GO:0048185)
0.1	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	1.2	GO:0045296	cadherin binding(GO:0045296)
0.1	1.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.8	GO:0005109	frizzled binding(GO:0005109)
0.1	0.2	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.1	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	0.4	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	1.0	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	2.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1	0.3	GO:0030507	spectrin binding(GO:0030507)
0.1	0.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.2	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.1	0.2	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1	0.6	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.7	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.5	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.1	3.2	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	3.8	GO:0008201	heparin binding(GO:0008201)
0.0	0.4	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.3	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.1	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0050544	arachidonic acid binding(GO:0050544)
0.0	0.2	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.3	GO:0016595	glutamate binding(GO:0016595)
0.0	0.2	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.6	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0031544	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.4	GO:0030553	cGMP binding(GO:0030553)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.1	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.0	0.4	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.6	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.9	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.3	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.3	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.6	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.1	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.4	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.3	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.3	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.3	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)
0.0	0.1	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	1.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.1	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.2	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0043515	kinetochore binding(GO:0043515)
0.0	1.2	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.0	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.2	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0008106	alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0	0.1	GO:0015459	potassium channel regulator activity(GO:0015459)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.1	GO:0005112	Notch binding(GO:0005112)
0.0	0.0	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.2	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.1	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.8	GO:0005179	hormone activity(GO:0005179)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.9	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.2	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.2	1.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	5.2	NABA COLLAGENS	Genes encoding collagen proteins
0.1	2.7	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	0.1	PID INSULIN PATHWAY	Insulin Pathway
0.1	3.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	2.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.1	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	0.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	0.5	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.1	2.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	1.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	6.7	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	2.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.4	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	1.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.6	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.8	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.5	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	4.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.5	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.5	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	2.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	4.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	0.2	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	1.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	1.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.8	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.3	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	2.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	5.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	1.6	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	1.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.1	0.2	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	1.5	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	2.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	0.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	1.6	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.1	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	0.5	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	1.4	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.9	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	1.3	REACTOME CELL CELL JUNCTION ORGANIZATION	Genes involved in Cell-cell junction organization
0.0	1.8	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.6	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.4	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.7	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.5	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	1.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.7	REACTOME MUSCLE CONTRACTION	Genes involved in Muscle contraction
0.0	0.1	REACTOME NEGATIVE REGULATION OF FGFR SIGNALING	Genes involved in Negative regulation of FGFR signaling
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.4	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.3	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.2	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.0	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.0	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.2	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME SIGNALING BY ERBB4	Genes involved in Signaling by ERBB4
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport

Results for HOXD10

Z-value: 2.39

Motif logo

Transcription factors associated with HOXD10

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXD10 motif across conditions

Conditions sorted by the z-value of the HOXD10 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD10

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: