Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for HOXD10

Z-value: 2.39

Motif logo

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Transcription factors associated with HOXD10

Gene Symbol Gene ID Gene Info
ENSG00000128710.5 HOXD10

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
HOXD10chr2_176981076_1769812741320.8945530.781.2e-02Click!
HOXD10chr2_176981554_1769817053220.7318800.442.3e-01Click!
HOXD10chr2_176982170_1769823219380.3076520.442.3e-01Click!
HOXD10chr2_176981739_1769818905070.5598380.255.2e-01Click!
HOXD10chr2_176983652_17698380324200.1141380.235.4e-01Click!

Activity of the HOXD10 motif across conditions

Conditions sorted by the z-value of the HOXD10 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr22_46477864_46478136 2.00 FLJ27365
hsa-mir-4763
1808
0.2
chr5_54456050_54456451 1.63 GPX8
glutathione peroxidase 8 (putative)
252
0.86
chr11_121968787_121969071 1.40 ENSG00000207971
.
1623
0.3
chr22_46462951_46463814 1.18 RP6-109B7.4

2389
0.16
chr3_114169976_114170457 1.13 ZBTB20
zinc finger and BTB domain containing 20
3314
0.33
chr5_66254399_66254664 1.02 MAST4
microtubule associated serine/threonine kinase family member 4
167
0.97
chr4_152146952_152147499 1.00 SH3D19
SH3 domain containing 19
7
0.98
chr2_197852125_197852688 0.98 ANKRD44
ankyrin repeat domain 44
12820
0.25
chr4_148944622_148945028 0.98 RP11-76G10.1

122797
0.06
chr12_78334342_78334902 0.94 NAV3
neuron navigator 3
25434
0.27
chr3_55520023_55520469 0.92 WNT5A
wingless-type MMTV integration site family, member 5A
1085
0.48
chr10_70321971_70322188 0.91 TET1
tet methylcytosine dioxygenase 1
1666
0.36
chr11_69454506_69454752 0.91 CCND1
cyclin D1
1226
0.52
chr22_36232318_36232521 0.87 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
3846
0.33
chr6_44424385_44424803 0.86 ENSG00000266619
.
21216
0.17
chr9_14312608_14313176 0.85 NFIB
nuclear factor I/B
774
0.71
chr6_169652381_169652976 0.81 THBS2
thrombospondin 2
432
0.89
chr12_59311038_59311457 0.79 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
2080
0.36
chr3_150089259_150089633 0.78 TSC22D2
TSC22 domain family, member 2
36676
0.21
chr9_21688149_21688723 0.78 ENSG00000244230
.
10877
0.24
chr7_116312981_116313724 0.78 MET
met proto-oncogene
893
0.68
chr7_114055343_114055580 0.77 FOXP2
forkhead box P2
83
0.98
chr15_93615075_93616283 0.76 RGMA
repulsive guidance molecule family member a
695
0.78
chr3_33318777_33319866 0.74 FBXL2
F-box and leucine-rich repeat protein 2
353
0.91
chr11_121968562_121968780 0.74 ENSG00000207971
.
1881
0.27
chr3_175244326_175245006 0.73 ENSG00000201648
.
82601
0.1
chr1_95330057_95330663 0.71 SLC44A3
solute carrier family 44, member 3
2527
0.28
chr4_86700210_86700446 0.71 ARHGAP24
Rho GTPase activating protein 24
469
0.88
chr15_30112674_30113382 0.71 TJP1
tight junction protein 1
723
0.64
chr4_54063057_54063462 0.69 ENSG00000207385
.
68475
0.13
chr11_94528525_94528870 0.69 AMOTL1
angiomotin like 1
27160
0.2
chr2_157749235_157750071 0.69 ENSG00000263848
.
122116
0.06
chr6_166259879_166260251 0.68 SDIM1
stress responsive DNAJB4 interacting membrane protein 1
49660
0.16
chr8_141733894_141734187 0.68 PTK2
protein tyrosine kinase 2
2153
0.35
chr1_215180647_215181021 0.68 KCNK2
potassium channel, subfamily K, member 2
1636
0.56
chr8_42063953_42065062 0.68 PLAT
plasminogen activator, tissue
576
0.71
chr15_96884556_96884898 0.67 ENSG00000222651
.
8237
0.16
chr15_35959426_35959743 0.64 DPH6
diphthamine biosynthesis 6
121191
0.07
chr7_114055046_114055222 0.63 FOXP2
forkhead box P2
21
0.98
chr9_22008020_22008450 0.63 CDKN2B
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
717
0.61
chr1_185704392_185704588 0.63 HMCN1
hemicentin 1
807
0.75
chr15_99788624_99789059 0.63 TTC23
tetratricopeptide repeat domain 23
895
0.51
chr1_57041430_57041821 0.63 PPAP2B
phosphatidic acid phosphatase type 2B
3616
0.34
chr6_169653692_169653887 0.62 THBS2
thrombospondin 2
350
0.92
chr6_19691587_19692480 0.62 ENSG00000200957
.
49273
0.18
chr11_36252522_36252860 0.62 COMMD9
COMM domain containing 9
58283
0.13
chr1_240250348_240250507 0.62 FMN2
formin 2
4753
0.3
chr1_179111271_179111703 0.62 ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
692
0.72
chr1_79043181_79043547 0.62 IFI44L
interferon-induced protein 44-like
42243
0.17
chr8_89311514_89311910 0.61 RP11-586K2.1

27353
0.2
chr5_142623144_142623555 0.61 ARHGAP26
Rho GTPase activating protein 26
36584
0.19
chr3_98700853_98701271 0.61 ENSG00000207331
.
73759
0.1
chr12_91504103_91504272 0.61 LUM
lumican
1421
0.48
chr3_104078695_104079148 0.59 ENSG00000265076
.
305281
0.01
chr8_60538222_60538702 0.59 ENSG00000201763
.
170018
0.04
chr3_29327656_29328192 0.59 RBMS3-AS3
RBMS3 antisense RNA 3
4293
0.26
chr15_96882948_96883133 0.59 ENSG00000222651
.
6550
0.16
chr5_32027565_32028229 0.59 ENSG00000266243
.
91632
0.07
chr2_164592268_164592669 0.58 FIGN
fidgetin
49
0.99
chr5_167000633_167001353 0.58 CTB-78F1.1

86493
0.1
chr7_94026049_94026200 0.57 COL1A2
collagen, type I, alpha 2
2251
0.42
chr7_134464463_134465343 0.57 CALD1
caldesmon 1
474
0.89
chr6_152085810_152086045 0.57 ESR1
estrogen receptor 1
39639
0.18
chr3_150064794_150064984 0.57 TSC22D2
TSC22 domain family, member 2
61233
0.14
chr3_100785098_100785499 0.57 ABI3BP
ABI family, member 3 (NESH) binding protein
72939
0.11
chr4_81195528_81195918 0.57 FGF5
fibroblast growth factor 5
7930
0.26
chr9_137535305_137535456 0.55 COL5A1
collagen, type V, alpha 1
1760
0.38
chr4_160169630_160170007 0.55 RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
18215
0.23
chr10_76684287_76684702 0.55 KAT6B
K(lysine) acetyltransferase 6B
86036
0.08
chr14_71022448_71023169 0.55 ADAM20
ADAM metallopeptidase domain 20
21076
0.17
chr2_190272115_190272296 0.55 WDR75
WD repeat domain 75
33954
0.2
chr7_134465998_134466492 0.55 CALD1
caldesmon 1
1816
0.49
chr19_47735595_47736220 0.55 BBC3
BCL2 binding component 3
116
0.95
chr7_83822850_83823057 0.54 SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
1264
0.65
chr22_36232996_36233711 0.54 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
2912
0.37
chr3_21736170_21736448 0.54 ZNF385D
zinc finger protein 385D
56618
0.16
chr20_6764834_6765429 0.54 BMP2
bone morphogenetic protein 2
16820
0.28
chr9_89738235_89738413 0.53 C9orf170
chromosome 9 open reading frame 170
25235
0.26
chr4_121990444_121990801 0.53 NDNF
neuron-derived neurotrophic factor
2534
0.31
chr18_74798828_74799607 0.53 MBP
myelin basic protein
18000
0.27
chr6_3473109_3473260 0.53 SLC22A23
solute carrier family 22, member 23
15928
0.27
chr5_39423074_39423254 0.53 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
1806
0.48
chr4_159093168_159093728 0.53 RP11-597D13.9

281
0.64
chr1_99729766_99730318 0.52 LPPR4
Lipid phosphate phosphatase-related protein type 4
194
0.97
chr18_30310087_30311054 0.52 AC012123.1
Uncharacterized protein
39188
0.17
chr1_8433877_8434267 0.52 RERE
arginine-glutamic acid dipeptide (RE) repeats
9174
0.19
chr3_114477857_114478359 0.52 ZBTB20
zinc finger and BTB domain containing 20
10
0.99
chr11_503866_504897 0.51 RNH1
ribonuclease/angiogenin inhibitor 1
171
0.89
chr4_152148504_152148764 0.51 SH3D19
SH3 domain containing 19
548
0.8
chr12_21927918_21928225 0.51 KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
316
0.88
chr11_12454847_12455344 0.51 PARVA
parvin, alpha
19187
0.24
chr18_59067267_59067515 0.51 ENSG00000206769
.
8563
0.3
chr2_152214605_152215087 0.51 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
740
0.63
chr17_79315981_79316442 0.50 TMEM105
transmembrane protein 105
11737
0.13
chr13_99629621_99629906 0.50 DOCK9
dedicator of cytokinesis 9
481
0.85
chr9_80437599_80437890 0.50 GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
171
0.98
chr21_30673835_30674113 0.50 BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
851
0.62
chr2_188418224_188418410 0.50 AC007319.1

559
0.57
chr7_94027821_94027972 0.50 COL1A2
collagen, type I, alpha 2
4023
0.33
chr4_187648403_187648661 0.50 FAT1
FAT atypical cadherin 1
656
0.82
chr6_152701109_152701260 0.50 SYNE1-AS1
SYNE1 antisense RNA 1
497
0.78
chr13_39992060_39992261 0.49 ENSG00000238408
.
29193
0.25
chr10_24755480_24755818 0.49 KIAA1217
KIAA1217
189
0.96
chr1_25895160_25895475 0.49 LDLRAP1
low density lipoprotein receptor adaptor protein 1
25246
0.17
chr11_121970307_121971111 0.49 ENSG00000207971
.
157
0.79
chr8_142048186_142048475 0.49 PTK2
protein tyrosine kinase 2
36121
0.17
chr3_190530283_190530682 0.49 GMNC
geminin coiled-coil domain containing
49922
0.18
chr3_149339263_149339595 0.49 WWTR1-IT1
WWTR1 intronic transcript 1 (non-protein coding)
28542
0.15
chr10_32438008_32438363 0.49 ENSG00000252482
.
24427
0.2
chr4_157700840_157701063 0.49 RP11-154F14.2

61560
0.13
chr22_40707066_40707217 0.48 ADSL
adenylosuccinate lyase
35366
0.15
chr22_40706773_40706982 0.48 ADSL
adenylosuccinate lyase
35630
0.14
chr12_76653631_76654077 0.48 ENSG00000223273
.
55677
0.14
chr18_53178087_53178424 0.48 TCF4
transcription factor 4
255
0.93
chr5_39418140_39418360 0.48 DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
6720
0.29
chr13_36343879_36344030 0.48 DCLK1
doublecortin-like kinase 1
85825
0.1
chr8_122515112_122515274 0.48 ENSG00000263525
.
40042
0.21
chr7_94026391_94026542 0.48 COL1A2
collagen, type I, alpha 2
2593
0.39
chr3_149801405_149801614 0.48 ENSG00000243321
.
5891
0.21
chr12_59434723_59435248 0.48 RP11-150C16.1

120565
0.06
chr7_116170513_116170982 0.47 CAV1
caveolin 1, caveolae protein, 22kDa
4400
0.18
chr1_1676260_1677404 0.47 SLC35E2
solute carrier family 35, member E2
526
0.68
chr5_141980216_141980760 0.47 AC005592.2

19075
0.18
chr1_196527542_196527719 0.47 ENSG00000265986
.
23981
0.22
chr6_132437274_132437503 0.47 ENSG00000265669
.
985
0.69
chr1_216704476_216705111 0.47 USH2A
Usher syndrome 2A (autosomal recessive, mild)
108055
0.08
chr5_35309735_35309886 0.46 PRLR
prolactin receptor
79016
0.1
chr5_78985270_78986298 0.46 CMYA5
cardiomyopathy associated 5
84
0.98
chr6_45523951_45524153 0.46 ENSG00000252738
.
89789
0.09
chr12_76422565_76423423 0.46 RP11-290L1.3

1280
0.41
chr3_79023077_79023270 0.46 ENSG00000240964
.
35731
0.2
chr5_102202832_102203172 0.46 PAM
peptidylglycine alpha-amidating monooxygenase
1182
0.66
chr6_11795100_11795449 0.46 ADTRP
androgen-dependent TFPI-regulating protein
12005
0.28
chr8_32506055_32506353 0.46 NRG1
neuregulin 1
847
0.76
chr3_89074301_89074693 0.46 EPHA3
EPH receptor A3
82177
0.12
chr13_24044512_24044663 0.46 SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
36746
0.21
chr21_28215844_28216573 0.45 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
112
0.98
chr3_114168204_114168554 0.45 ZBTB20
zinc finger and BTB domain containing 20
5151
0.29
chr6_12427440_12427701 0.45 ENSG00000223321
.
20557
0.28
chr15_59622162_59622355 0.45 ENSG00000199512
.
11358
0.14
chr3_109884338_109884502 0.45 ENSG00000221206
.
386392
0.01
chr7_19155354_19155672 0.45 TWIST1
twist family bHLH transcription factor 1
1782
0.28
chr9_684288_685148 0.45 RP11-130C19.3

837
0.67
chr9_21677527_21678485 0.45 ENSG00000244230
.
21307
0.21
chr2_202904203_202904368 0.45 FZD7
frizzled family receptor 7
4975
0.19
chr1_196622943_196623164 0.45 CFH
complement factor H
1867
0.41
chr6_48078606_48078757 0.45 PTCHD4
patched domain containing 4
42256
0.22
chr8_62686205_62686405 0.45 ENSG00000264408
.
58958
0.14
chr1_185688405_185688780 0.45 HMCN1
hemicentin 1
15091
0.26
chr6_85484117_85484534 0.45 TBX18
T-box 18
10088
0.3
chr14_62230360_62230511 0.45 SNAPC1
small nuclear RNA activating complex, polypeptide 1, 43kDa
1360
0.55
chr8_79468522_79468695 0.45 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
34858
0.19
chr18_52626293_52626952 0.45 CCDC68
coiled-coil domain containing 68
117
0.97
chr12_29744562_29745018 0.44 TMTC1
transmembrane and tetratricopeptide repeat containing 1
12367
0.26
chr18_18775376_18775547 0.44 GREB1L
growth regulation by estrogen in breast cancer-like
46742
0.15
chr1_179096167_179096689 0.44 ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
15751
0.19
chr11_85961580_85961731 0.44 EED
embryonic ectoderm development
5379
0.24
chr10_29922441_29923089 0.44 SVIL
supervillin
1136
0.54
chr3_93878024_93878443 0.44 ENSG00000253062
.
60823
0.12
chr4_114679395_114679686 0.44 CAMK2D
calcium/calmodulin-dependent protein kinase II delta
2684
0.42
chr1_236073367_236073780 0.44 ENSG00000206803
.
5142
0.2
chr11_44383183_44383459 0.44 ALX4
ALX homeobox 4
51605
0.17
chr11_114033998_114034413 0.44 ENSG00000221112
.
76554
0.09
chr22_36310772_36312004 0.44 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
23557
0.25
chr5_31806865_31807016 0.43 PDZD2
PDZ domain containing 2
7909
0.14
chr11_94529113_94529270 0.43 AMOTL1
angiomotin like 1
27654
0.2
chr14_71255809_71256187 0.43 MAP3K9
mitogen-activated protein kinase kinase kinase 9
5836
0.3
chr6_125550220_125550378 0.43 TPD52L1
tumor protein D52-like 1
9308
0.28
chr3_29964845_29964996 0.43 RBMS3-AS1
RBMS3 antisense RNA 1
10727
0.31
chr4_41157110_41157449 0.43 ENSG00000207198
.
41320
0.14
chr4_170189368_170189538 0.43 SH3RF1
SH3 domain containing ring finger 1
1655
0.5
chr10_4719979_4720356 0.43 AKR1E2
aldo-keto reductase family 1, member E2
108654
0.07
chr8_106645652_106645917 0.43 RP11-642D21.1

36435
0.19
chr5_124071713_124071892 0.43 RP11-436H11.5

934
0.37
chr5_119802087_119802238 0.43 PRR16
proline rich 16
836
0.77
chr6_152792590_152792847 0.42 SYNE1
spectrin repeat containing, nuclear envelope 1
1047
0.59
chr1_94711175_94711488 0.42 ARHGAP29
Rho GTPase activating protein 29
8142
0.25
chr1_215742028_215742345 0.42 KCTD3
potassium channel tetramerization domain containing 3
1451
0.56
chr8_25864992_25865143 0.42 EBF2
early B-cell factor 2
33937
0.23
chr2_20261222_20261477 0.42 RP11-644K8.1

9454
0.17
chr4_153270968_153271263 0.42 FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
1157
0.54
chr5_61389218_61389599 0.42 ENSG00000251983
.
53084
0.18
chr15_96881380_96881711 0.42 ENSG00000222651
.
5055
0.17
chr2_230845561_230845747 0.42 ENSG00000206725
.
7623
0.17
chr18_46472333_46472626 0.42 SMAD7
SMAD family member 7
2396
0.36
chr6_85470567_85470756 0.42 TBX18
T-box 18
2412
0.42
chr12_64581322_64581595 0.42 ENSG00000212298
.
17115
0.15
chr4_86749229_86749793 0.42 ARHGAP24
Rho GTPase activating protein 24
465
0.88
chr1_218672576_218672996 0.42 C1orf143
chromosome 1 open reading frame 143
10652
0.26
chr18_10058041_10058330 0.42 ENSG00000263630
.
52991
0.15
chr12_8814882_8815352 0.41 MFAP5
microfibrillar associated protein 5
98
0.95
chr12_63025061_63025357 0.41 ENSG00000238475
.
19746
0.14
chr11_89113858_89114276 0.41 NOX4
NADPH oxidase 4
109833
0.07
chr4_148009583_148009791 0.41 TTC29
tetratricopeptide repeat domain 29
142653
0.05
chr10_4358088_4358256 0.41 ENSG00000207124
.
198972
0.03
chr15_60684685_60685107 0.41 ANXA2
annexin A2
1400
0.54
chr5_72417110_72417261 0.41 TMEM171
transmembrane protein 171
789
0.61
chr7_42355171_42355392 0.41 GLI3
GLI family zinc finger 3
78623
0.12
chr4_119962368_119962530 0.41 SYNPO2
synaptopodin 2
17823
0.26
chr7_151433344_151433930 0.41 PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
237
0.95

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of HOXD10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0031223 auditory behavior(GO:0031223)
0.5 2.1 GO:0043589 skin morphogenesis(GO:0043589)
0.5 2.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.5 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.3 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.4 1.6 GO:0070141 response to UV-A(GO:0070141)
0.4 1.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.3 1.0 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.3 1.3 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.3 1.1 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.3 1.0 GO:0010664 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 1.0 GO:0008218 bioluminescence(GO:0008218)
0.3 0.8 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.3 0.8 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.3 1.3 GO:0048875 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.3 0.8 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.2 0.5 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.2 1.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2 0.5 GO:0060068 vagina development(GO:0060068)
0.2 0.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.7 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.6 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 0.6 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.2 1.6 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.2 0.8 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.2 0.2 GO:0090103 cochlea morphogenesis(GO:0090103)
0.2 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.4 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.2 0.4 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.2 0.6 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.2 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 0.7 GO:0010107 potassium ion import(GO:0010107)
0.2 0.9 GO:1903672 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2 0.5 GO:0010842 retina layer formation(GO:0010842)
0.2 0.5 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2 0.5 GO:0060437 lung growth(GO:0060437)
0.2 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.5 GO:0022605 oogenesis stage(GO:0022605)
0.2 0.2 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.2 0.2 GO:0051584 regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.2 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.2 0.5 GO:1903332 regulation of protein folding(GO:1903332)
0.2 0.5 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.2 1.1 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.3 GO:0010193 response to ozone(GO:0010193)
0.1 1.3 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.1 GO:0043301 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.1 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.7 GO:0043206 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.1 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.3 GO:1903053 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1 1.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.4 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.1 0.4 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.5 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.4 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.1 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 1.2 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.2 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.1 0.5 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.6 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 0.8 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.7 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 0.6 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.3 GO:0001738 morphogenesis of a polarized epithelium(GO:0001738)
0.1 0.9 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.8 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.4 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.7 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.1 GO:0060535 trachea cartilage morphogenesis(GO:0060535) cartilage morphogenesis(GO:0060536)
0.1 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.1 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.1 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.1 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.2 GO:0060242 contact inhibition(GO:0060242)
0.1 0.5 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.1 0.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.1 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.1 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1 0.5 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.1 0.2 GO:0051014 actin filament severing(GO:0051014)
0.1 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1 0.3 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 0.3 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.4 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.1 0.4 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.1 0.4 GO:0007619 courtship behavior(GO:0007619)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0033087 negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.2 GO:0060438 trachea development(GO:0060438)
0.1 0.7 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 0.2 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.1 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.1 0.4 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 1.9 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.1 1.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.5 GO:0007530 sex determination(GO:0007530)
0.1 0.8 GO:0008347 glial cell migration(GO:0008347)
0.1 0.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.9 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 0.1 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.1 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.3 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.1 0.4 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.7 GO:0030325 adrenal gland development(GO:0030325)
0.1 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.1 0.2 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 2.1 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.1 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.3 GO:0015871 choline transport(GO:0015871)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.1 GO:1903170 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.3 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.1 0.3 GO:0080111 DNA demethylation(GO:0080111)
0.1 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1 0.6 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.3 GO:0001660 fever generation(GO:0001660)
0.1 0.2 GO:0034105 positive regulation of tissue remodeling(GO:0034105)
0.1 0.1 GO:0042268 regulation of cytolysis(GO:0042268)
0.1 0.4 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.3 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.2 GO:0051451 myoblast migration(GO:0051451)
0.1 0.5 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.1 GO:0021794 thalamus development(GO:0021794)
0.1 0.2 GO:0014850 response to muscle activity(GO:0014850)
0.1 0.1 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.1 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 0.2 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.1 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.1 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.1 0.2 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 0.2 GO:0010873 positive regulation of cholesterol esterification(GO:0010873)
0.1 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.1 GO:0072201 negative regulation of mesenchymal cell proliferation(GO:0072201)
0.1 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 0.5 GO:0006949 syncytium formation(GO:0006949)
0.1 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 0.2 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.1 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.2 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.1 0.1 GO:0031639 plasminogen activation(GO:0031639)
0.1 0.1 GO:0042640 anagen(GO:0042640)
0.1 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1 0.2 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.1 0.7 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.1 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.1 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.1 0.9 GO:0007566 embryo implantation(GO:0007566)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.4 GO:0008038 neuron recognition(GO:0008038)
0.0 0.1 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.4 GO:0048566 embryonic digestive tract development(GO:0048566)
0.0 0.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.8 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0 0.5 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0001759 organ induction(GO:0001759)
0.0 0.1 GO:0010656 negative regulation of muscle cell apoptotic process(GO:0010656)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0019098 reproductive behavior(GO:0019098)
0.0 0.4 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.2 GO:0002675 positive regulation of acute inflammatory response(GO:0002675)
0.0 0.1 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 1.0 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0051956 negative regulation of amino acid transport(GO:0051956)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.3 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.3 GO:0007494 midgut development(GO:0007494)
0.0 0.2 GO:0010611 regulation of cardiac muscle hypertrophy(GO:0010611)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.7 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.3 GO:0001508 action potential(GO:0001508)
0.0 0.2 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 4.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0051955 regulation of amino acid transport(GO:0051955)
0.0 1.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:2000647 negative regulation of stem cell proliferation(GO:2000647)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.2 GO:0002076 osteoblast development(GO:0002076)
0.0 0.4 GO:0030901 midbrain development(GO:0030901)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.0 GO:0072193 positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0016246 RNA interference(GO:0016246)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0060442 branching involved in prostate gland morphogenesis(GO:0060442)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.0 GO:0034445 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.2 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.0 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.0 0.4 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.3 GO:0042522 regulation of tyrosine phosphorylation of Stat5 protein(GO:0042522)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0060206 estrous cycle phase(GO:0060206)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.4 GO:0014075 response to amine(GO:0014075)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0010829 negative regulation of glucose transport(GO:0010829)
0.0 0.1 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.0 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0 0.1 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.1 GO:0019471 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471) peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0009111 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.4 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.2 GO:0071385 cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.5 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.0 0.1 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 0.1 GO:0014044 Schwann cell development(GO:0014044)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0047496 vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0 0.1 GO:0009648 photoperiodism(GO:0009648)
0.0 0.0 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.0 0.0 GO:0070528 protein kinase C signaling(GO:0070528)
0.0 0.0 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.1 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0060581 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.0 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.6 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.0 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.0 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.4 GO:0007215 glutamate receptor signaling pathway(GO:0007215)
0.0 0.0 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.0 GO:0035510 DNA dealkylation(GO:0035510)
0.0 0.0 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.1 GO:0090201 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.0 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.0 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.0 GO:0097576 vacuole fusion(GO:0097576)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 2.6 GO:0006936 muscle contraction(GO:0006936)
0.0 0.3 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0003208 cardiac ventricle morphogenesis(GO:0003208)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0030539 male genitalia development(GO:0030539)
0.0 0.0 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.0 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.0 GO:0060157 urinary bladder development(GO:0060157)
0.0 0.0 GO:0034331 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.0 0.0 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0009208 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.0 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0090025 regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:0007492 endoderm development(GO:0007492)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.0 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.0 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) GTP metabolic process(GO:0046039) prosthetic group metabolic process(GO:0051189)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.0 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.0 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0006734 NADH metabolic process(GO:0006734)
0.0 0.0 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 0.0 GO:0032095 regulation of response to food(GO:0032095)
0.0 0.0 GO:0021754 facial nucleus development(GO:0021754)
0.0 0.1 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 0.0 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.0 0.0 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.1 GO:0007613 memory(GO:0007613)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.0 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0021889 olfactory bulb interneuron differentiation(GO:0021889)
0.0 0.0 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0042983 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.3 3.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 1.0 GO:0030056 hemidesmosome(GO:0030056)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.4 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.2 0.5 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.5 GO:0043259 laminin-10 complex(GO:0043259)
0.2 0.8 GO:0071437 invadopodium(GO:0071437)
0.2 1.3 GO:0030128 AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.1 0.6 GO:0005606 laminin-1 complex(GO:0005606)
0.1 0.4 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.7 GO:0016342 catenin complex(GO:0016342)
0.1 0.7 GO:0001527 microfibril(GO:0001527)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.3 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.5 GO:0005916 fascia adherens(GO:0005916)
0.1 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.3 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 2.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.2 GO:0014704 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1 0.7 GO:0030315 T-tubule(GO:0030315)
0.1 1.1 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 3.4 GO:0005604 basement membrane(GO:0005604)
0.1 0.4 GO:0010369 chromocenter(GO:0010369)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.1 GO:0002142 stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.1 1.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.3 GO:0005581 collagen trimer(GO:0005581)
0.1 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.1 4.9 GO:0030016 myofibril(GO:0030016)
0.0 0.0 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.1 GO:0031941 filamentous actin(GO:0031941)
0.0 2.5 GO:0030426 growth cone(GO:0030426)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 8.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.2 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 1.1 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 1.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.3 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0043296 apical junction complex(GO:0043296)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 2.5 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.7 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 2.2 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.8 GO:0016459 myosin complex(GO:0016459)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.0 GO:0030427 site of polarized growth(GO:0030427)
0.0 0.0 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.0 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.0 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 0.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.4 1.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 1.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.3 1.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.3 1.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.3 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 0.9 GO:0050682 AF-2 domain binding(GO:0050682)
0.3 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 0.8 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.2 2.7 GO:0070064 proline-rich region binding(GO:0070064)
0.2 0.6 GO:0016842 amidine-lyase activity(GO:0016842)
0.2 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.6 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.2 2.7 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.5 GO:0017166 vinculin binding(GO:0017166)
0.2 2.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.2 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 0.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.4 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1 0.4 GO:0032558 purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1 0.7 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.1 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.4 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.4 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.9 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 1.7 GO:0043498 obsolete cell surface binding(GO:0043498)
0.1 2.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 4.3 GO:0005518 collagen binding(GO:0005518)
0.1 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 1.0 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.1 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.4 GO:0042805 actinin binding(GO:0042805)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.3 GO:0035198 miRNA binding(GO:0035198)
0.1 0.3 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.1 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.3 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.5 GO:0048185 activin binding(GO:0048185)
0.1 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.2 GO:0045296 cadherin binding(GO:0045296)
0.1 1.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.8 GO:0005109 frizzled binding(GO:0005109)
0.1 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.4 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.1 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.0 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 2.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 0.3 GO:0030507 spectrin binding(GO:0030507)
0.1 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 3.2 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 3.8 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0031708 bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.2 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.2 GO:0001595 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.2 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0031544 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.4 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.1 GO:0070325 lipoprotein particle receptor binding(GO:0070325)
0.0 0.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.1 GO:0000295 adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.1 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.1 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0043121 neurotrophin binding(GO:0043121)
0.0 0.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0043515 kinetochore binding(GO:0043515)
0.0 1.2 GO:0003704 obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0 0.0 GO:0015211 purine nucleoside transmembrane transporter activity(GO:0015211)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.0 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.0 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.9 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.0 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 1.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 5.2 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.1 PID INSULIN PATHWAY Insulin Pathway
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.9 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 6.7 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 2.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.5 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.1 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 4.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 2.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 0.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.1 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 2.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 5.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 2.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.1 1.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 0.6 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.3 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.6 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.7 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME NEGATIVE REGULATION OF FGFR SIGNALING Genes involved in Negative regulation of FGFR signaling
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.0 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.0 0.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.1 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport