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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for HOXD9

Z-value: 2.58

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Transcription factors associated with HOXD9

Gene Symbol	Gene ID	Gene Info
HOXD9 Ensembl NCBI GeneCards UniProt	ENSG00000128709.10	homeobox D9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_176987145_176987880	HOXD9	424	0.631690	-0.09	8.3e-01	Click!
chr2_176988599_176988880	HOXD9	1651	0.162770	-0.04	9.2e-01	Click!
chr2_176987899_176988234	HOXD9	978	0.292253	-0.02	9.6e-01	Click!

Activity of the HOXD9 motif across conditions

Conditions sorted by the z-value of the HOXD9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_120687963_120688114	0.92	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)	686	0.74
chr8_126960676_126960849	0.89	ENSG00000206695	.	47567	0.2
chr15_60881660_60881911	0.88	RORA	RAR-related orphan receptor A	2955	0.3
chr13_74806186_74806399	0.78	ENSG00000206617	.	57059	0.16
chr2_160291322_160291473	0.77	BAZ2B	bromodomain adjacent to zinc finger domain, 2B	1936	0.41
chr14_53593743_53594005	0.77	DDHD1	DDHD domain containing 1	22930	0.17
chr7_150436038_150436258	0.76	GIMAP5	GTPase, IMAP family member 5	1712	0.32
chr10_63999686_63999837	0.74	RTKN2	rhotekin 2	3739	0.34
chr13_99966823_99967055	0.73	GPR183	G protein-coupled receptor 183	7280	0.21
chr5_110560650_110560918	0.71	CAMK4	calcium/calmodulin-dependent protein kinase IV	1000	0.62
chr14_99710021_99710272	0.70	AL109767.1		19139	0.2
chr6_112078365_112078719	0.69	FYN	FYN oncogene related to SRC, FGR, YES	1775	0.47
chr6_128221212_128221624	0.69	THEMIS	thymocyte selection associated	685	0.81
chr4_40210765_40210916	0.68	RHOH	ras homolog family member H	8876	0.22
chr4_181931488_181931639	0.67	ENSG00000251742	.	824698	0.0
chr21_32567568_32567719	0.66	TIAM1	T-cell lymphoma invasion and metastasis 1	65104	0.13
chr4_78738053_78738204	0.66	CNOT6L	CCR4-NOT transcription complex, subunit 6-like	2089	0.42
chr6_128221625_128221781	0.64	THEMIS	thymocyte selection associated	400	0.91
chr3_18477985_18478171	0.62	SATB1	SATB homeobox 1	1333	0.48
chr4_114680711_114680982	0.61	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	1378	0.6
chr5_80257520_80257735	0.60	CTC-459I6.1		901	0.48
chr3_95425254_95425405	0.59	ENSG00000221477	.	460417	0.01
chr14_22747947_22748098	0.58	ENSG00000238634	.	137135	0.04
chr2_197028334_197028485	0.58	STK17B	serine/threonine kinase 17b	7038	0.21
chr2_175354621_175354772	0.57	GPR155	G protein-coupled receptor 155	2874	0.27
chr14_22466666_22466817	0.57	ENSG00000238634	.	144146	0.04
chr14_22966536_22967037	0.56	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	10615	0.1
chr14_22995827_22995978	0.56	TRAJ15	T cell receptor alpha joining 15	2678	0.16
chr3_142663096_142663442	0.56	RP11-372E1.4		6187	0.16
chr12_14540385_14540755	0.55	ATF7IP	activating transcription factor 7 interacting protein	2572	0.35
chr8_121744015_121744417	0.55	RP11-713M15.1		29277	0.22
chr18_67623543_67623764	0.55	CD226	CD226 molecule	253	0.95
chr1_226922484_226922931	0.55	ITPKB	inositol-trisphosphate 3-kinase B	2452	0.34
chr1_222578153_222578517	0.54	ENSG00000222399	.	98742	0.08
chr5_39198391_39198564	0.54	FYB	FYN binding protein	4652	0.32
chr12_82826657_82826808	0.54	METTL25	methyltransferase like 25	33594	0.21
chr11_85962233_85962384	0.53	EED	embryonic ectoderm development	6032	0.24
chrX_1776580_1777384	0.53	ASMT	acetylserotonin O-methyltransferase	21691	0.23
chr21_32553132_32553283	0.53	TIAM1	T-cell lymphoma invasion and metastasis 1	50668	0.17
chr8_8727017_8727210	0.53	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	24042	0.18
chr7_46104168_46104319	0.52	ENSG00000239004	.	89206	0.09
chr1_178698179_178698330	0.52	RP11-428K3.1		2834	0.23
chr17_38018967_38019134	0.52	IKZF3	IKAROS family zinc finger 3 (Aiolos)	1329	0.36
chr3_125086964_125087115	0.52	ZNF148	zinc finger protein 148	7054	0.21
chr1_102637571_102637722	0.52	OLFM3	olfactomedin 3	175060	0.04
chr4_143324564_143324979	0.51	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	27641	0.28
chr21_25801249_25801648	0.51	ENSG00000232512	.	671997	0.0
chr15_86235334_86235485	0.51	RP11-815J21.1		8931	0.12
chr3_187086208_187087126	0.51	RTP4	receptor (chemosensory) transporter protein 4	547	0.82
chr6_143228096_143228637	0.51	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	37972	0.2
chr12_47607778_47608233	0.50	PCED1B	PC-esterase domain containing 1B	2047	0.36
chr1_39500021_39500217	0.50	NDUFS5	NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)	8129	0.18
chrY_1726497_1727385	0.50	ENSG00000251841	.	925849	0.0
chr1_209941434_209941773	0.50	TRAF3IP3	TRAF3 interacting protein 3	230	0.9
chr6_73134749_73134900	0.49	RIMS1	regulating synaptic membrane exocytosis 1	58392	0.16
chr10_6627878_6628029	0.49	PRKCQ	protein kinase C, theta	5690	0.34
chr14_99732558_99733007	0.49	AL109767.1		3497	0.26
chr1_117301810_117301961	0.49	CD2	CD2 molecule	4796	0.25
chrX_110366573_110366760	0.49	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	361	0.93
chr9_128408983_128409218	0.48	MAPKAP1	mitogen-activated protein kinase associated protein 1	3596	0.32
chr2_37828778_37829033	0.48	AC006369.2		1626	0.48
chr4_109084210_109084462	0.48	LEF1	lymphoid enhancer-binding factor 1	3121	0.29
chr11_104669483_104669764	0.48	CASP12	caspase 12 (gene/pseudogene)	99518	0.08
chr14_22997122_22997273	0.48	TRAJ15	T cell receptor alpha joining 15	1383	0.28
chr12_92534627_92535592	0.48	C12orf79	chromosome 12 open reading frame 79	1335	0.39
chr2_240219542_240220118	0.48	ENSG00000265215	.	7327	0.19
chr6_136604397_136604710	0.48	BCLAF1	BCL2-associated transcription factor 1	3549	0.27
chr3_151964474_151964662	0.48	MBNL1	muscleblind-like splicing regulator 1	21261	0.21
chr14_99711224_99711514	0.48	AL109767.1		17916	0.2
chr7_50349443_50349694	0.47	IKZF1	IKAROS family zinc finger 1 (Ikaros)	1250	0.61
chr4_143322143_143322556	0.47	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	30063	0.27
chr3_88857237_88857388	0.47	EPHA3	EPH receptor A3	299362	0.01
chr7_8011263_8011414	0.47	AC006042.7		1804	0.29
chr5_156618387_156618538	0.47	ITK	IL2-inducible T-cell kinase	10625	0.13
chr12_94683132_94683283	0.46	RP11-1105G2.3	Uncharacterized protein	9251	0.17
chr1_101702315_101703350	0.46	S1PR1	sphingosine-1-phosphate receptor 1	388	0.67
chr1_92349361_92349512	0.46	TGFBR3	transforming growth factor, beta receptor III	2230	0.34
chr17_37933702_37934037	0.46	IKZF3	IKAROS family zinc finger 3 (Aiolos)	609	0.66
chr7_150217655_150217806	0.46	GIMAP7	GTPase, IMAP family member 7	5812	0.21
chr2_213962198_213962349	0.46	IKZF2	IKAROS family zinc finger 2 (Helios)	51080	0.16
chr14_22982199_22982350	0.45	TRAJ15	T cell receptor alpha joining 15	16306	0.1
chr13_38755447_38755598	0.45	UFM1	ubiquitin-fold modifier 1	168466	0.04
chr16_79630640_79632238	0.45	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	2360	0.43
chr14_22999291_22999566	0.45	TRAJ15	T cell receptor alpha joining 15	848	0.46
chr4_30432123_30432274	0.45	PCDH7	protocadherin 7	289839	0.01
chr8_125382183_125382334	0.45	TMEM65	transmembrane protein 65	2675	0.33
chr6_112079694_112079977	0.45	FYN	FYN oncogene related to SRC, FGR, YES	482	0.87
chr3_32994357_32994508	0.45	CCR4	chemokine (C-C motif) receptor 4	1366	0.54
chr14_23000530_23000681	0.44	TRAJ15	T cell receptor alpha joining 15	2025	0.2
chr10_31637499_31637650	0.44	RP11-192P3.5		15363	0.19
chr1_100852790_100852941	0.44	ENSG00000216067	.	8534	0.21
chr17_33571906_33572066	0.44	SLFN5	schlafen family member 5	1878	0.24
chr12_92530033_92530184	0.44	C12orf79	chromosome 12 open reading frame 79	689	0.67
chr14_22986632_22986941	0.44	TRAJ15	T cell receptor alpha joining 15	11794	0.1
chr15_96422557_96422745	0.44	ENSG00000222076	.	133618	0.06
chr21_35305474_35305968	0.44	LINC00649	long intergenic non-protein coding RNA 649	2203	0.25
chr13_30947300_30947451	0.43	KATNAL1	katanin p60 subunit A-like 1	65754	0.12
chr18_48718913_48719435	0.43	MEX3C	mex-3 RNA binding family member C	3955	0.31
chr3_152002678_152002963	0.43	MBNL1	muscleblind-like splicing regulator 1	14374	0.21
chr18_2982488_2982849	0.43	LPIN2	lipin 2	203	0.93
chr7_129546585_129546878	0.42	UBE2H	ubiquitin-conjugating enzyme E2H	44436	0.1
chr16_89827893_89828073	0.42	FANCA	Fanconi anemia, complementation group A	16513	0.12
chr20_46606950_46607101	0.42	ENSG00000238785	.	73933	0.11
chr14_22974214_22974379	0.42	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	18125	0.09
chr5_156608214_156608444	0.42	ITK	IL2-inducible T-cell kinase	492	0.72
chr14_98101436_98101587	0.42	ENSG00000240730	.	105001	0.08
chr2_158292578_158292753	0.42	CYTIP	cytohesin 1 interacting protein	3261	0.28
chr5_81762775_81762926	0.42	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	161684	0.04
chr11_6766362_6766695	0.42	GVINP1	GTPase, very large interferon inducible pseudogene 1	23417	0.11
chr1_175946531_175946682	0.42	ENSG00000252906	.	8930	0.26
chr2_197788792_197788943	0.42	PGAP1	post-GPI attachment to proteins 1	2587	0.36
chr12_47606090_47606241	0.42	PCED1B	PC-esterase domain containing 1B	3887	0.26
chr2_225041045_225041196	0.42	ENSG00000211987	.	63153	0.14
chr2_20776643_20776868	0.41	HS1BP3-IT1	HS1BP3 intronic transcript 1 (non-protein coding)	15553	0.21
chr2_204572488_204572658	0.41	CD28	CD28 molecule	1157	0.58
chrX_78404824_78405114	0.41	GPR174	G protein-coupled receptor 174	21500	0.29
chr6_106500939_106501090	0.41	PRDM1	PR domain containing 1, with ZNF domain	33181	0.19
chr5_156609776_156609927	0.41	ITK	IL2-inducible T-cell kinase	2014	0.23
chr2_38826937_38827218	0.41	HNRNPLL	heterogeneous nuclear ribonucleoprotein L-like	91	0.96
chr14_22955963_22956254	0.41	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	63	0.95
chr17_46506355_46506700	0.41	SKAP1	src kinase associated phosphoprotein 1	1025	0.46
chr10_63993468_63993619	0.41	RTKN2	rhotekin 2	2479	0.4
chr6_35636218_35636369	0.41	ENSG00000265527	.	3727	0.17
chr4_40212550_40212701	0.41	RHOH	ras homolog family member H	10661	0.22
chr5_110560941_110561277	0.40	CAMK4	calcium/calmodulin-dependent protein kinase IV	1325	0.51
chr6_152622546_152623206	0.40	SYNE1	spectrin repeat containing, nuclear envelope 1	382	0.91
chr1_198620819_198621442	0.40	PTPRC	protein tyrosine phosphatase, receptor type, C	12838	0.23
chr3_141105086_141105320	0.40	ZBTB38	zinc finger and BTB domain containing 38	91	0.98
chr6_143264540_143264691	0.40	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	1723	0.46
chr14_23013651_23013802	0.40	AE000662.92	Uncharacterized protein	11808	0.1
chr12_22486636_22486842	0.40	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	358	0.93
chr1_172150545_172150914	0.40	DNM3OS	DNM3 opposite strand/antisense RNA	36795	0.15
chr6_149729706_149729857	0.40	SUMO4	small ubiquitin-like modifier 4	8286	0.19
chr10_109195445_109195596	0.40	ENSG00000200079	.	25798	0.28
chr2_204801338_204802214	0.40	ICOS	inducible T-cell co-stimulator	273	0.95
chr1_65429872_65430170	0.39	JAK1	Janus kinase 1	2166	0.38
chr10_29896797_29896948	0.39	ENSG00000216035	.	5597	0.21
chr3_32996346_32996497	0.39	CCR4	chemokine (C-C motif) receptor 4	3355	0.33
chr12_40012898_40013112	0.39	ABCD2	ATP-binding cassette, sub-family D (ALD), member 2	548	0.81
chr17_33373915_33374211	0.39	RFFL	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase	4693	0.13
chr17_33498778_33498929	0.39	RP11-799D4.3		4822	0.12
chr15_60882704_60882968	0.39	RORA	RAR-related orphan receptor A	1904	0.39
chr6_95260200_95260351	0.39	ENSG00000252249	.	671451	0.0
chr10_116285471_116285868	0.38	ABLIM1	actin binding LIM protein 1	925	0.69
chr10_35421285_35421436	0.38	ENSG00000253054	.	3011	0.19
chr1_207092315_207092466	0.38	FAIM3	Fas apoptotic inhibitory molecule 3	2822	0.2
chr21_32555155_32555306	0.38	TIAM1	T-cell lymphoma invasion and metastasis 1	52691	0.16
chr14_99736204_99736825	0.38	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	1051	0.56
chr2_111616545_111616696	0.38	ACOXL	acyl-CoA oxidase-like	53724	0.17
chr3_111261912_111262220	0.38	CD96	CD96 molecule	1069	0.62
chr14_23006174_23006390	0.38	TRAJ15	T cell receptor alpha joining 15	7702	0.11
chrX_20996388_20996539	0.38	ENSG00000206716	.	236292	0.02
chr2_198756913_198757256	0.38	PLCL1	phospholipase C-like 1	82102	0.1
chrX_109559064_109559215	0.38	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	2173	0.29
chr14_61789636_61789944	0.37	ENSG00000247287	.	254	0.65
chr3_111267390_111267660	0.37	CD96	CD96 molecule	6528	0.27
chr5_106729540_106729691	0.37	EFNA5	ephrin-A5	276713	0.02
chr11_67009621_67010037	0.37	KDM2A	lysine (K)-specific demethylase 2A	2311	0.2
chr12_911875_912026	0.37	ENSG00000221439	.	21651	0.2
chr4_48134207_48134444	0.37	TXK	TXK tyrosine kinase	1948	0.29
chr18_53067346_53067650	0.37	TCF4	transcription factor 4	1068	0.61
chr9_94707911_94708062	0.37	ROR2	receptor tyrosine kinase-like orphan receptor 2	3176	0.38
chr14_92331424_92331867	0.37	TC2N	tandem C2 domains, nuclear	2228	0.32
chr7_142496042_142496273	0.37	PRSS3P2	protease, serine, 3 pseudogene 2	15026	0.17
chr12_133698893_133699044	0.37	ZNF891	zinc finger protein 891	464	0.68
chr7_107389164_107389315	0.37	AC002467.7		4213	0.19
chr1_89737700_89738180	0.37	GBP5	guanylate binding protein 5	547	0.77
chr4_143488164_143488362	0.37	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	6441	0.35
chr20_43517414_43517860	0.37	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta	3244	0.19
chr10_54571770_54571921	0.37	MBL2	mannose-binding lectin (protein C) 2, soluble	40385	0.17
chr2_210654487_210655159	0.37	UNC80	unc-80 homolog (C. elegans)	18060	0.25
chr15_38852692_38852843	0.37	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	287	0.91
chr4_154411300_154411567	0.37	KIAA0922	KIAA0922	23932	0.22
chr13_50809972_50810123	0.37	ENSG00000221198	.	127326	0.05
chr6_135407557_135407764	0.37	HBS1L	HBS1-like (S. cerevisiae)	16534	0.2
chr15_101136944_101137114	0.37	LINS	lines homolog (Drosophila)	112	0.95
chr4_103448739_103448914	0.37	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	24294	0.18
chr1_67400477_67400653	0.37	MIER1	mesoderm induction early response 1, transcriptional regulator	4639	0.23
chr1_186292481_186292673	0.37	ENSG00000202025	.	11517	0.17
chr6_119398487_119399078	0.37	FAM184A	family with sequence similarity 184, member A	755	0.67
chr15_38853288_38853439	0.37	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	883	0.6
chr2_214004488_214004639	0.37	IKZF2	IKAROS family zinc finger 2 (Helios)	8790	0.3
chr1_111212990_111213454	0.36	KCNA3	potassium voltage-gated channel, shaker-related subfamily, member 3	4433	0.21
chr10_677138_677289	0.36	RP11-809C18.3		2635	0.23
chr5_125785966_125786206	0.36	GRAMD3	GRAM domain containing 3	11951	0.22
chr10_135450644_135451234	0.36	FRG2B	FSHD region gene 2 family, member B	10640	0.18
chr6_135343190_135343341	0.36	HBS1L	HBS1-like (S. cerevisiae)	5029	0.24
chr5_35854071_35854416	0.36	IL7R	interleukin 7 receptor	1446	0.44
chr5_119523820_119523971	0.36	ENSG00000251975	.	149453	0.05
chr2_158296564_158297076	0.36	CYTIP	cytohesin 1 interacting protein	894	0.5
chr16_22383801_22383959	0.36	CDR2	cerebellar degeneration-related protein 2, 62kDa	2058	0.22
chr2_136705908_136706203	0.36	DARS	aspartyl-tRNA synthetase	27932	0.17
chr12_92172398_92172689	0.36	C12orf79	chromosome 12 open reading frame 79	358254	0.01
chr2_225809390_225809894	0.36	DOCK10	dedicator of cytokinesis 10	2140	0.45
chr2_242051303_242051464	0.36	MTERFD2	MTERF domain containing 2	9636	0.14
chr17_4118969_4119120	0.36	ENSG00000207390	.	22981	0.12
chr3_8089018_8089169	0.36	LMCD1-AS1	LMCD1 antisense RNA 1 (head to head)	31099	0.21
chrX_78200973_78201449	0.36	P2RY10	purinergic receptor P2Y, G-protein coupled, 10	293	0.95
chr2_237446290_237446506	0.36	ACKR3	atypical chemokine receptor 3	30032	0.19
chr6_143997751_143997902	0.35	PHACTR2	phosphatase and actin regulator 2	1276	0.57

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.6	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2	0.7	GO:0010761	fibroblast migration(GO:0010761)
0.2	1.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2	1.4	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.2	0.6	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.4	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.2	0.8	GO:0043374	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	1.5	GO:0043383	negative T cell selection(GO:0043383)
0.2	0.2	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2	0.5	GO:0045059	positive thymic T cell selection(GO:0045059)
0.1	0.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	1.1	GO:0006491	N-glycan processing(GO:0006491)
0.1	0.3	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.3	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.1	GO:0002513	tolerance induction to self antigen(GO:0002513)
0.1	0.5	GO:0001757	somite specification(GO:0001757)
0.1	0.5	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.4	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.5	GO:0002507	tolerance induction(GO:0002507)
0.1	0.3	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.3	GO:0010459	negative regulation of heart rate(GO:0010459)
0.1	0.3	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.2	GO:0044413	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.3	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.4	GO:0031579	membrane raft organization(GO:0031579)
0.1	0.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.1	0.3	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.6	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.3	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.1	0.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.4	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.1	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	0.2	GO:0032071	regulation of endodeoxyribonuclease activity(GO:0032071)
0.1	0.4	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	0.2	GO:0001821	histamine secretion(GO:0001821)
0.1	0.5	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1	0.2	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.2	GO:1904035	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.1	0.8	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.1	0.3	GO:0015705	iodide transport(GO:0015705)
0.1	0.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	0.3	GO:0019987	obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.4	GO:0002335	mature B cell differentiation(GO:0002335)
0.1	0.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.4	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0060197	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1	0.1	GO:0021754	facial nucleus development(GO:0021754)
0.1	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1	0.3	GO:0044380	protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1	0.2	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0022417	protein maturation by protein folding(GO:0022417)
0.1	0.3	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1	0.2	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.2	GO:0010508	positive regulation of autophagy(GO:0010508)
0.1	1.3	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.1	0.3	GO:0060317	cardiac epithelial to mesenchymal transition(GO:0060317)
0.1	0.3	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.2	GO:0071883	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.2	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.4	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:1901722	regulation of cell proliferation involved in kidney development(GO:1901722)
0.0	0.2	GO:0032823	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.1	GO:0090312	positive regulation of protein deacetylation(GO:0090312)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:1903077	negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0	0.1	GO:0070932	histone H3 deacetylation(GO:0070932) histone H4 deacetylation(GO:0070933)
0.0	0.1	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.7	GO:0034199	activation of protein kinase A activity(GO:0034199)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.4	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.4	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.3	GO:0030260	entry into host cell(GO:0030260) entry into host(GO:0044409) entry into cell of other organism involved in symbiotic interaction(GO:0051806) entry into other organism involved in symbiotic interaction(GO:0051828)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0043369	alpha-beta T cell lineage commitment(GO:0002363) CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0	0.2	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	0.3	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.3	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	1.4	GO:0031294	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.8	GO:0006997	nucleus organization(GO:0006997)
0.0	0.2	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.2	GO:0048641	regulation of skeletal muscle tissue development(GO:0048641)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.1	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	1.4	GO:0060333	interferon-gamma-mediated signaling pathway(GO:0060333)
0.0	0.6	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.2	GO:0050858	negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0	1.5	GO:0007498	mesoderm development(GO:0007498)
0.0	0.1	GO:0019885	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.0	GO:0001743	optic placode formation(GO:0001743)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:0009048	dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.0	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.9	GO:0050852	T cell receptor signaling pathway(GO:0050852)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.1	GO:0045354	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0030186	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.0	GO:0033079	immature T cell proliferation(GO:0033079)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.2	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.3	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.2	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.2	GO:0051319	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0046666	retinal cell programmed cell death(GO:0046666)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.2	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.0	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.0	GO:0050854	regulation of antigen receptor-mediated signaling pathway(GO:0050854)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.3	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.0	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.0	GO:0002707	negative regulation of lymphocyte mediated immunity(GO:0002707)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.0	GO:0060242	contact inhibition(GO:0060242)
0.0	0.0	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0046881	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.0	GO:0021937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.1	GO:0034219	carbohydrate transmembrane transport(GO:0034219)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.0	GO:0030832	regulation of actin filament length(GO:0030832)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.0	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.3	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.0	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.3	GO:1900181	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0070198	protein localization to chromosome, telomeric region(GO:0070198)
0.0	0.0	GO:0070253	somatostatin secretion(GO:0070253)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.2	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.1	GO:0070265	necrotic cell death(GO:0070265)
0.0	0.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.2	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.5	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.1	GO:0051569	regulation of histone H3-K4 methylation(GO:0051569)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.0	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.0	GO:0060596	mammary placode formation(GO:0060596)
0.0	0.0	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.0	GO:0070472	uterine smooth muscle contraction(GO:0070471) regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0	0.2	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.1	GO:0008655	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.1	GO:0070071	proton-transporting two-sector ATPase complex assembly(GO:0070071)
0.0	0.0	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.1	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.0	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0090003	regulation of establishment of protein localization to plasma membrane(GO:0090003) regulation of protein localization to plasma membrane(GO:1903076) regulation of protein localization to cell periphery(GO:1904375)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.0	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0061042	vascular wound healing(GO:0061042) regulation of vascular wound healing(GO:0061043)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.0	GO:0060513	prostatic bud formation(GO:0060513)
0.0	0.2	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.2	GO:0006513	protein monoubiquitination(GO:0006513)
0.0	0.0	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.0	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.8	GO:0008154	actin polymerization or depolymerization(GO:0008154)
0.0	0.0	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.1	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:1901985	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.0	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.0	GO:0019441	tryptophan catabolic process to kynurenine(GO:0019441)
0.0	0.0	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.0	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.0	0.0	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.0	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0060457	negative regulation of digestive system process(GO:0060457)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.0	GO:0032288	myelin assembly(GO:0032288)
0.0	0.0	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.0	GO:0014002	astrocyte development(GO:0014002)
0.0	0.0	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.0	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0000730	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:0033567	lagging strand elongation(GO:0006273) DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.3	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	1.0	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.5	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.1	0.5	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.5	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.2	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0001772	immunological synapse(GO:0001772)
0.1	0.2	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	1.2	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.2	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.5	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031904	endosome lumen(GO:0031904)
0.0	0.4	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.2	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.2	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.2	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.3	GO:0043209	myelin sheath(GO:0043209)
0.0	0.3	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0070188	obsolete Stn1-Ten1 complex(GO:0070188)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	1.1	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	2.2	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.0	GO:0060199	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0016580	Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.7	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.2	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.2	0.6	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	2.9	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	1.8	GO:0004697	protein kinase C activity(GO:0004697)
0.1	0.8	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1	0.7	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	0.3	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	0.3	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.4	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.7	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.8	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.1	1.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.2	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	1.2	GO:0015026	coreceptor activity(GO:0015026)
0.1	0.2	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1	0.5	GO:0070410	co-SMAD binding(GO:0070410)
0.1	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.5	GO:0005522	profilin binding(GO:0005522)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.1	1.1	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.1	0.3	GO:0051400	BH domain binding(GO:0051400)
0.1	0.8	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.4	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.8	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.4	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.4	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0016531	copper chaperone activity(GO:0016531)
0.0	0.2	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	1.5	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.2	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.2	GO:0070403	NAD+ binding(GO:0070403)
0.0	0.3	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.4	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.2	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0045502	dynein binding(GO:0045502)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.2	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.2	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.3	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.3	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.3	GO:0046625	sphingolipid binding(GO:0046625)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.0	0.3	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.9	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.3	GO:0005344	oxygen transporter activity(GO:0005344)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.7	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	1.5	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.1	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:1901474	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	1.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.2	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.3	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.1	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.0	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0035591	signaling adaptor activity(GO:0035591)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0031432	titin binding(GO:0031432)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.1	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.5	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.4	GO:0003823	antigen binding(GO:0003823)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0060590	ATPase regulator activity(GO:0060590)
0.0	0.4	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0030955	potassium ion binding(GO:0030955)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.0	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.0	GO:0016530	metallochaperone activity(GO:0016530)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0035240	dopamine binding(GO:0035240)
0.0	0.0	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	0.8	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.3	PID REELIN PATHWAY	Reelin signaling pathway
0.1	2.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.5	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.5	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.5	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	1.8	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	1.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.5	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	1.0	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.8	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.0	0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	1.0	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.5	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.5	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.5	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.0	0.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.2	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.2	1.8	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.1	2.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	2.3	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.1	1.0	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.9	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	0.8	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	1.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1	0.8	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	1.1	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.1	0.9	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.1	0.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	1.4	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	0.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	1.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	1.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.0	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	0.2	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.1	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.3	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.2	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	0.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS	Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.0	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.0	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.0	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators

Results for HOXD9

Z-value: 2.58

Motif logo

Transcription factors associated with HOXD9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the HOXD9 motif across conditions

Conditions sorted by the z-value of the HOXD9 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXD9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: