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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for IKZF2

Z-value: 1.11

Motif logo

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Transcription factors associated with IKZF2

Gene Symbol Gene ID Gene Info
IKZF2
ENSG00000030419.12 IKAROS family zinc finger 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_213969171_213969322IKZF2441070.1871800.636.8e-02Click!
chr2_213969618_213969769IKZF2436600.1886750.637.1e-02Click!
chr2_213983567_213983718IKZF2297110.2370980.571.1e-01Click!
chr2_213983796_213984145IKZF2293830.2382390.511.6e-01Click!
chr2_214016688_214017732IKZF2590.9867110.491.8e-01Click!

Activity of the IKZF2 motif across conditions

Conditions sorted by the z-value of the IKZF2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_110720958_110721647 0.33 ATP2A2
 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
 1816
 0.41
chr12_116872831_116873001 0.31 ENSG00000264037
 .
 6793
 0.3
chr3_29327656_29328192 0.28 RBMS3-AS3
 RBMS3 antisense RNA 3
 4293
 0.26
chr18_74277400_74278128 0.28 LINC00908
 long intergenic non-protein coding RNA 908
 36890
 0.17
chr18_20558047_20558453 0.28 RBBP8
 retinoblastoma binding protein 8
 9445
 0.15
chr11_79861921_79862072 0.28 ENSG00000200146
 .
 377008
 0.01
chr3_136649286_136649636 0.25 NCK1
 NCK adaptor protein 1
 117
 0.97
chr3_172240144_172241280 0.25 TNFSF10
 tumor necrosis factor (ligand) superfamily, member 10
 553
 0.83
chr3_155108862_155109013 0.25 ENSG00000272096
 .
 46675
 0.16
chr9_34745557_34745708 0.25 FAM205A
 family with sequence similarity 205, member A
 16168
 0.13
chr3_5055440_5055591 0.25 BHLHE40-AS1
 BHLHE40 antisense RNA 1
 33869
 0.15
chr12_32635081_32635232 0.25 FGD4
 FYVE, RhoGEF and PH domain containing 4
 3750
 0.26
chr20_11898508_11899014 0.24 BTBD3
 BTB (POZ) domain containing 3
 196
 0.82
chr14_103887907_103888058 0.24 MARK3
 MAP/microtubule affinity-regulating kinase 3
 35406
 0.12
chr7_93694115_93694266 0.24 BET1
 Bet1 golgi vesicular membrane trafficking protein
 60496
 0.13
chr21_39756340_39756646 0.23 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
 87645
 0.09
chrX_73071645_73072457 0.23 RP13-216E22.5
117269
 0.06
chr10_21807539_21808360 0.23 SKIDA1
 SKI/DACH domain containing 1
 1101
 0.4
chr1_47489778_47489953 0.22 CYP4X1
 cytochrome P450, family 4, subfamily X, polypeptide 1
 625
 0.75
chr8_51783438_51783589 0.22 ENSG00000201316
 .
 144068
 0.05
chr1_77751257_77751408 0.22 AK5
 adenylate kinase 5
 2568
 0.34
chr7_129255259_129255410 0.22 NRF1
 nuclear respiratory factor 1
 3737
 0.29
chr5_71806938_71807120 0.21 ZNF366
 zinc finger protein 366
 3475
 0.33
chr21_34415086_34415237 0.21 OLIG2
 oligodendrocyte lineage transcription factor 2
 16918
 0.17
chr18_19192929_19193396 0.21 SNRPD1
 small nuclear ribonucleoprotein D1 polypeptide 16kDa
 870
 0.52
chr21_27944686_27945456 0.21 CYYR1
 cysteine/tyrosine-rich 1
 424
 0.91
chr21_16388120_16388271 0.21 NRIP1
 nuclear receptor interacting protein 1
 13506
 0.22
chr16_85160610_85160761 0.21 FAM92B
 family with sequence similarity 92, member B
 14571
 0.21
chr6_150083012_150083330 0.21 PCMT1
 protein-L-isoaspartate (D-aspartate) O-methyltransferase
 11991
 0.14
chr1_9600473_9600668 0.21 SLC25A33
 solute carrier family 25 (pyrimidine nucleotide carrier), member 33
 1029
 0.58
chr12_96839645_96840068 0.21 ENSG00000263364
 .
 2598
 0.28
chr2_158694717_158695163 0.21 ACVR1
 activin A receptor, type I
 101
 0.97
chr6_157104323_157104474 0.21 RP11-230C9.3
2809
 0.25
chr2_178032482_178032633 0.21 ENSG00000201102
 .
 27154
 0.12
chr7_27957803_27957954 0.21 ENSG00000265382
 .
 37772
 0.18
chr20_47448799_47448989 0.21 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 4474
 0.31
chr6_1314742_1314893 0.20 FOXQ1
 forkhead box Q1
 2142
 0.4
chr5_20109661_20109812 0.20 CDH18
 cadherin 18, type 2
 121397
 0.07
chr14_89673001_89673195 0.20 FOXN3
 forkhead box N3
 26010
 0.24
chr7_48675933_48676084 0.20 ABCA13
 ATP-binding cassette, sub-family A (ABC1), member 13
 128540
 0.06
chr6_109414649_109415318 0.20 SESN1
 sestrin 1
 1039
 0.42
chr5_64588165_64588316 0.20 ENSG00000207439
 .
 169044
 0.03
chr2_102466743_102466894 0.20 MAP4K4
 mitogen-activated protein kinase kinase kinase kinase 4
 5621
 0.28
chr3_196697012_196697163 0.20 PIGZ
 phosphatidylinositol glycan anchor biosynthesis, class Z
 1345
 0.35
chr6_27247805_27248026 0.20 POM121L2
 POM121 transmembrane nucleoporin-like 2
 31176
 0.15
chr12_90287998_90288165 0.20 ENSG00000252823
 .
 140245
 0.05
chr20_10399686_10399837 0.20 MKKS
 McKusick-Kaufman syndrome
 12809
 0.19
chr2_113591900_113592051 0.19 IL1B
 interleukin 1, beta
 2036
 0.29
chr15_43885389_43885540 0.19 CKMT1B
 creatine kinase, mitochondrial 1B
 170
 0.9
chr3_129383548_129383699 0.19 TMCC1
 transmembrane and coiled-coil domain family 1
 8054
 0.22
chr3_189515104_189515255 0.19 TP63
 tumor protein p63
 7589
 0.27
chr1_150481112_150481644 0.19 ECM1
 extracellular matrix protein 1
 795
 0.48
chr5_171389606_171389757 0.19 FBXW11
 F-box and WD repeat domain containing 11
 15079
 0.25
chr3_87000039_87000329 0.19 VGLL3
 vestigial like 3 (Drosophila)
 39668
 0.23
chr21_17959283_17959568 0.19 ENSG00000207863
 .
 3132
 0.31
chr2_64878829_64879050 0.19 SERTAD2
 SERTA domain containing 2
 2108
 0.38
chr12_50410240_50410391 0.18 RACGAP1
 Rac GTPase activating protein 1
 188
 0.92
chr3_42864733_42864884 0.18 ACKR2
 atypical chemokine receptor 2
 3697
 0.14
chr7_27211508_27211659 0.18 HOXA10
 homeobox A10
 2342
 0.09
chr7_30326052_30326514 0.18 ZNRF2
 zinc and ring finger 2
 2360
 0.29
chr2_192842795_192842946 0.18 AC098617.1
43768
 0.2
chr3_132036252_132036528 0.18 ACPP
 acid phosphatase, prostate
 139
 0.97
chr12_66198631_66198915 0.18 HMGA2
 high mobility group AT-hook 2
 19138
 0.21
chr9_90133589_90133740 0.18 DAPK1
 death-associated protein kinase 1
 19744
 0.23
chr2_172964285_172964474 0.18 DLX2
 distal-less homeobox 2
 3249
 0.26
chr2_9348603_9349207 0.18 ASAP2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 2011
 0.46
chr9_90955493_90955644 0.18 ENSG00000252299
 .
 33616
 0.2
chr17_57289227_57289378 0.18 SMG8
 SMG8 nonsense mediated mRNA decay factor
 518
 0.64
chr17_56490979_56491130 0.18 RNF43
 ring finger protein 43
 1948
 0.27
chr12_13332071_13332496 0.18 EMP1
 epithelial membrane protein 1
 17367
 0.23
chr2_66803096_66803300 0.18 MEIS1
 Meis homeobox 1
 67139
 0.13
chr14_94255244_94255403 0.18 PRIMA1
 proline rich membrane anchor 1
 496
 0.86
chr6_86349087_86349642 0.18 SYNCRIP
 synaptotagmin binding, cytoplasmic RNA interacting protein
 3345
 0.23
chr12_104360447_104360701 0.18 TDG
 thymine-DNA glycosylase
 910
 0.37
chr3_71478030_71478538 0.18 ENSG00000221264
 .
 112956
 0.06
chr19_31830586_31830803 0.18 AC007796.1
9093
 0.25
chr3_99619729_99619880 0.17 FILIP1L
 filamin A interacting protein 1-like
 24758
 0.22
chr20_61555717_61555868 0.17 DIDO1
 death inducer-obliterator 1
 2029
 0.26
chr11_67979557_67979856 0.17 SUV420H1
 suppressor of variegation 4-20 homolog 1 (Drosophila)
 515
 0.8
chr10_108792061_108792212 0.17 ENSG00000200626
 .
 62357
 0.16
chr15_90364678_90364977 0.17 ANPEP
 alanyl (membrane) aminopeptidase
 6194
 0.14
chr8_70745749_70746362 0.17 RP11-159H10.3
291
 0.62
chr6_99798162_99798313 0.17 FAXC
 failed axon connections homolog (Drosophila)
 706
 0.71
chr2_145438866_145439017 0.17 ZEB2
 zinc finger E-box binding homeobox 2
 160320
 0.04
chr4_71388674_71388825 0.17 AMTN
 amelotin
 4447
 0.22
chr6_108886554_108887901 0.17 FOXO3
 forkhead box O3
 5158
 0.32
chr16_87469465_87469755 0.17 ZCCHC14
 zinc finger, CCHC domain containing 14
 2870
 0.22
chr11_47615339_47615925 0.17 C1QTNF4
 C1q and tumor necrosis factor related protein 4
 579
 0.54
chr3_42135461_42135612 0.17 TRAK1
 trafficking protein, kinesin binding 1
 2974
 0.36
chr12_51422377_51422723 0.17 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
 201
 0.91
chr1_28385256_28385469 0.17 EYA3
 eyes absent homolog 3 (Drosophila)
 764
 0.61
chr7_22861355_22861506 0.17 TOMM7
 translocase of outer mitochondrial membrane 7 homolog (yeast)
 533
 0.81
chr5_51742403_51742554 0.17 ITGA1
 integrin, alpha 1
 341252
 0.01
chr18_24083261_24083412 0.17 KCTD1
 potassium channel tetramerization domain containing 1
 43627
 0.17
chr10_118897625_118897901 0.17 VAX1
 ventral anterior homeobox 1
 49
 0.97
chr9_13278507_13279169 0.17 RP11-272P10.2
348
 0.67
chr12_48176505_48176789 0.17 AC004466.1
 Uncharacterized protein
 2059
 0.24
chr15_98538729_98539013 0.17 ENSG00000252477
 .
 30400
 0.18
chr6_65214990_65215141 0.17 RP11-349P19.1
127377
 0.06
chr8_38857241_38857490 0.16 ADAM9
 ADAM metallopeptidase domain 9
 2860
 0.19
chr8_117449236_117449387 0.16 ENSG00000264815
 .
 149723
 0.04
chr1_157014914_157015379 0.16 ARHGEF11
 Rho guanine nucleotide exchange factor (GEF) 11
 16
 0.98
chr6_37136440_37136591 0.16 PIM1
 pim-1 oncogene
 1464
 0.41
chr3_112931196_112931871 0.16 BOC
 BOC cell adhesion associated, oncogene regulated
 124
 0.97
chrX_73471805_73471956 0.16 ENSG00000265727
 .
 9144
 0.12
chr1_214619591_214619742 0.16 PTPN14
 protein tyrosine phosphatase, non-receptor type 14
 18480
 0.26
chr20_14317720_14318261 0.16 FLRT3
 fibronectin leucine rich transmembrane protein 3
 264
 0.94
chr15_57373111_57373262 0.16 ENSG00000222586
 .
 114591
 0.06
chr19_56166514_56167932 0.16 U2AF2
 U2 small nuclear RNA auxiliary factor 2
 792
 0.34
chr3_119807952_119808228 0.16 GSK3B
 glycogen synthase kinase 3 beta
 4423
 0.23
chr4_42153064_42153252 0.16 BEND4
 BEN domain containing 4
 1737
 0.5
chr9_2160189_2160438 0.16 SMARCA2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 368
 0.87
chr8_48572289_48573010 0.16 SPIDR
 scaffolding protein involved in DNA repair
 423
 0.86
chr5_112762315_112762466 0.16 CTD-2201G3.1
6885
 0.21
chr2_17009553_17009704 0.16 FAM49A
 family with sequence similarity 49, member A
 162029
 0.04
chr2_198464213_198464591 0.15 RFTN2
 raftlin family member 2
 18217
 0.19
chr15_43985226_43985377 0.15 CKMT1A
 creatine kinase, mitochondrial 1A
 203
 0.87
chr13_78659821_78660303 0.15 RNF219-AS1
 RNF219 antisense RNA 1
 30772
 0.24
chr3_171065824_171066073 0.15 ENSG00000222506
 .
 91367
 0.09
chr19_11449502_11449733 0.15 RAB3D
 RAB3D, member RAS oncogene family
 727
 0.43
chr17_26369297_26369946 0.15 NLK
 nemo-like kinase
 244
 0.91
chr6_26184757_26184908 0.15 HIST1H2BE
 histone cluster 1, H2be
 874
 0.29
chr4_164253130_164253399 0.15 NPY1R
 neuropeptide Y receptor Y1
 484
 0.84
chr1_67398755_67399224 0.15 MIER1
 mesoderm induction early response 1, transcriptional regulator
 3063
 0.27
chr8_48770878_48771029 0.15 ENSG00000211562
 .
 31666
 0.17
chr20_4415632_4415783 0.15 ADRA1D
 adrenoceptor alpha 1D
 185986
 0.03
chr2_186509945_186510096 0.15 ENSG00000212581
 .
 16481
 0.26
chr1_34368788_34368939 0.15 RP5-1007G16.1
27796
 0.2
chr5_130066537_130066688 0.15 ENSG00000252514
 .
 344239
 0.01
chr14_65566001_65566152 0.15 MAX
 MYC associated factor X
 2981
 0.21
chr20_44632803_44632954 0.15 MMP9
 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
 4669
 0.14
chr7_79767051_79767278 0.15 GNAI1
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
 2093
 0.45
chr1_86284190_86284341 0.15 ENSG00000201620
 .
 65216
 0.13
chr14_35871775_35873043 0.15 NFKBIA
 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
 937
 0.68
chr2_27631132_27631707 0.15 PPM1G
 protein phosphatase, Mg2+/Mn2+ dependent, 1G
 1030
 0.33
chrX_16825753_16826181 0.15 TXLNG
 taxilin gamma
 21412
 0.16
chr15_39886218_39886369 0.15 CTD-2033D15.1
139
 0.96
chr13_27975562_27975713 0.15 ENSG00000201242
 .
 1087
 0.48
chr7_93999537_93999688 0.15 COL1A2
 collagen, type I, alpha 2
 24261
 0.25
chr2_140023256_140023407 0.15 ENSG00000206901
 .
 245663
 0.02
chr18_12315741_12315987 0.15 TUBB6
 tubulin, beta 6 class V
 4898
 0.19
chr11_75210272_75210450 0.15 GDPD5
 glycerophosphodiester phosphodiesterase domain containing 5
 8565
 0.15
chr3_168864469_168864620 0.15 MECOM
 MDS1 and EVI1 complex locus
 81
 0.99
chr7_28724839_28725039 0.15 CREB5
 cAMP responsive element binding protein 5
 659
 0.83
chr15_91204059_91204503 0.14 RP11-387D10.3
311
 0.88
chr4_31024444_31024595 0.14 RP11-619J20.1
228927
 0.02
chr6_145124672_145124823 0.14 UTRN
 utrophin
 4230
 0.38
chr7_155090835_155091229 0.14 INSIG1
 insulin induced gene 1
 761
 0.7
chr6_137532057_137532208 0.14 IFNGR1
 interferon gamma receptor 1
 7519
 0.26
chr8_25070650_25071114 0.14 DOCK5
 dedicator of cytokinesis 5
 28502
 0.2
chr1_183156151_183156302 0.14 LAMC2
 laminin, gamma 2
 803
 0.7
chr10_77158203_77158354 0.14 ENSG00000237149
 .
 2999
 0.24
chr17_26220981_26221377 0.14 LYRM9
 LYR motif containing 9
 770
 0.4
chr10_97154342_97154493 0.14 SORBS1
 sorbin and SH3 domain containing 1
 21035
 0.25
chr5_54605223_54605374 0.14 SKIV2L2
 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
 1469
 0.33
chr15_45933283_45933523 0.14 SQRDL
 sulfide quinone reductase-like (yeast)
 4676
 0.21
chr1_159061696_159061989 0.14 AIM2
 absent in melanoma 2
 15151
 0.17
chr2_60764234_60764468 0.14 BCL11A
 B-cell CLL/lymphoma 11A (zinc finger protein)
 16189
 0.22
chr3_193852851_193853388 0.14 HES1
 hes family bHLH transcription factor 1
 815
 0.62
chr4_143322143_143322556 0.14 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 30063
 0.27
chr15_67334158_67334332 0.14 SMAD3
 SMAD family member 3
 21856
 0.25
chr20_57431129_57431280 0.14 GNAS
 GNAS complex locus
 971
 0.45
chr11_130818088_130818239 0.14 SNX19
 sorting nexin 19
 31759
 0.21
chr4_187491209_187491867 0.14 MTNR1A
 melatonin receptor 1A
 14817
 0.17
chr2_190647319_190647470 0.14 ORMDL1
 ORM1-like 1 (S. cerevisiae)
 714
 0.49
chr10_27815365_27815516 0.14 RAB18
 RAB18, member RAS oncogene family
 21892
 0.24
chr15_59062577_59062767 0.14 FAM63B
 family with sequence similarity 63, member B
 841
 0.54
chr4_124426780_124427488 0.14 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 106011
 0.08
chr13_48796681_48797014 0.14 ITM2B
 integral membrane protein 2B
 10447
 0.26
chr5_76527145_76527311 0.14 PDE8B
 phosphodiesterase 8B
 17459
 0.23
chr1_174160405_174160556 0.14 ENSG00000238872
 .
 8888
 0.23
chr1_231469833_231470794 0.14 SPRTN
 SprT-like N-terminal domain
 2537
 0.25
chr13_21000022_21000173 0.14 ENSG00000263978
 .
 7888
 0.27
chr2_238732566_238732717 0.14 RBM44
 RNA binding motif protein 44
 24820
 0.17
chr2_144382037_144382188 0.14 AC092652.1
24342
 0.17
chr6_21597329_21597632 0.14 SOX4
 SRY (sex determining region Y)-box 4
 3409
 0.4
chr1_215742028_215742345 0.14 KCTD3
 potassium channel tetramerization domain containing 3
 1451
 0.56
chr11_737225_737376 0.14 TALDO1
 transaldolase 1
 10029
 0.07
chr2_217859430_217859581 0.14 AC007563.1
120850
 0.05
chr1_151963774_151963995 0.14 S100A10
 S100 calcium binding protein A10
 1170
 0.39
chr8_12989527_12990464 0.14 DLC1
 deleted in liver cancer 1
 988
 0.62
chr1_109583292_109583606 0.14 WDR47
 WD repeat domain 47
 720
 0.6
chr1_161703743_161703894 0.14 ENSG00000241347
 .
 1780
 0.22
chr15_38558851_38559240 0.14 SPRED1
 sprouty-related, EVH1 domain containing 1
 13663
 0.3
chr2_175202799_175202950 0.14 AC018470.1
 Uncharacterized protein FLJ46347
 723
 0.62
chr12_29434762_29434913 0.13 RP11-996F15.2
35944
 0.16
chr8_66752673_66753180 0.13 PDE7A
 phosphodiesterase 7A
 817
 0.75
chr9_140524792_140524954 0.13 EHMT1
 euchromatic histone-lysine N-methyltransferase 1
 11419
 0.13
chr5_14036124_14036305 0.13 DNAH5
 dynein, axonemal, heavy chain 5
 91562
 0.09
chr8_98928953_98929409 0.13 MATN2
 matrilin 2
 14388
 0.23
chr9_17136040_17136191 0.13 CNTLN
 centlein, centrosomal protein
 1077
 0.67
chr8_71359268_71359419 0.13 ENSG00000253143
 .
 33379
 0.17
chr16_75033273_75033750 0.13 ZNRF1
 zinc and ring finger 1, E3 ubiquitin protein ligase
 268
 0.92
chr6_122719971_122720474 0.13 HSF2
 heat shock transcription factor 2
 469
 0.87
chr7_74074778_74074955 0.13 GTF2I
 general transcription factor IIi
 2509
 0.33
chr20_45982305_45982568 0.13 RP4-569M23.2
1131
 0.31
chr4_159417737_159417888 0.13 RP11-781M16.2
13248
 0.22
chr16_19769260_19769411 0.13 CTD-2380F24.1
8031
 0.18
chr1_43151006_43151188 0.13 YBX1
 Y box binding protein 1
 2439
 0.25
chr5_39412000_39412151 0.13 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
 12895
 0.26

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of IKZF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.2 GO:0010193 response to ozone(GO:0010193)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.2 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.0 0.1 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0032413 negative regulation of ion transmembrane transporter activity(GO:0032413)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.2 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0002138 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.3 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.1 GO:0032823 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.1 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.0 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0031659 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031657) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.0 GO:0032632 interleukin-3 production(GO:0032632)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0070391 response to lipoteichoic acid(GO:0070391) cellular response to lipoteichoic acid(GO:0071223)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.0 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:2000178 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0043552 regulation of phosphatidylinositol 3-kinase activity(GO:0043551) positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.0 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0021801 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.0 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.2 GO:0060039 pericardium development(GO:0060039)
0.0 0.1 GO:0032730 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.0 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.0 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0060573 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.0 GO:0021778 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.1 GO:0045008 depyrimidination(GO:0045008)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0098930 axonal transport(GO:0098930)
0.0 0.0 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.0 GO:0045002 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.0 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.1 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.0 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.0 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.1 GO:0006534 cysteine metabolic process(GO:0006534)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.0 GO:2000757 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 0.0 GO:0033504 floor plate development(GO:0033504)
0.0 0.0 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.3 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.0 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.2 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.0 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.3 GO:0019079 viral genome replication(GO:0019079)
0.0 0.0 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.3 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.4 GO:0045178 basal part of cell(GO:0045178)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477)
0.0 0.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.0 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.0 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.0 GO:0019958 C-X-C chemokine binding(GO:0019958) interleukin-8 binding(GO:0019959)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0043236 laminin binding(GO:0043236)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0034584 piRNA binding(GO:0034584)
0.0 0.0 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.0 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation