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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for IRF2_STAT2_IRF8_IRF1

Z-value: 6.52

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol	Gene ID	Gene Info
IRF2 Ensembl NCBI GeneCards UniProt	ENSG00000168310.6	interferon regulatory factor 2
STAT2 Ensembl NCBI GeneCards UniProt	ENSG00000170581.9	signal transducer and activator of transcription 2
IRF8 Ensembl NCBI GeneCards UniProt	ENSG00000140968.6	interferon regulatory factor 8
IRF1 Ensembl NCBI GeneCards UniProt	ENSG00000125347.9	interferon regulatory factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_131833252_131833403	IRF1	6837	0.143235	0.41	2.8e-01	Click!
chr5_131831030_131831229	IRF1	4639	0.155983	-0.38	3.1e-01	Click!
chr5_131822252_131822403	IRF1	3010	0.181720	-0.22	5.8e-01	Click!
chr5_131823400_131823551	IRF1	1862	0.254758	0.21	5.8e-01	Click!
chr5_131831286_131831908	IRF1	5107	0.151976	-0.20	6.1e-01	Click!
chr4_185327944_185328095	IRF2	11725	0.207489	-0.70	3.5e-02	Click!
chr4_185435112_185435265	IRF2	39454	0.151552	0.65	5.8e-02	Click!
chr4_185279118_185279269	IRF2	60551	0.108707	-0.64	6.3e-02	Click!
chr4_185278861_185279012	IRF2	60808	0.108202	-0.60	8.7e-02	Click!
chr4_185276503_185276684	IRF2	63151	0.103678	-0.52	1.6e-01	Click!
chr16_85887206_85887357	IRF8	45128	0.102513	-0.88	1.9e-03	Click!
chr16_85947812_85947963	IRF8	32	0.983661	-0.52	1.5e-01	Click!
chr16_85887601_85887752	IRF8	44733	0.103616	-0.52	1.5e-01	Click!
chr16_85942617_85942768	IRF8	98	0.977364	-0.45	2.2e-01	Click!
chr16_86020719_86020879	IRF8	72880	0.109594	0.45	2.3e-01	Click!
chr12_56753180_56753331	STAT2	603	0.512666	0.42	2.6e-01	Click!
chr12_56754222_56754408	STAT2	405	0.670120	-0.19	6.2e-01	Click!
chr12_56753471_56753911	STAT2	167	0.881735	0.15	6.9e-01	Click!

Activity of the IRF2_STAT2_IRF8_IRF1 motif across conditions

Conditions sorted by the z-value of the IRF2_STAT2_IRF8_IRF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_29485980_29486219	2.87	RP11-142O6.1		25899	0.14
chr18_22239957_22240733	2.86	HRH4	histamine receptor H4	199652	0.02
chr5_81763009_81763176	2.61	ATP6AP1L	ATPase, H+ transporting, lysosomal accessory protein 1-like	161926	0.04
chr18_42366702_42366923	2.54	SETBP1	SET binding protein 1	89683	0.1
chr6_118985728_118985996	2.52	CEP85L	centrosomal protein 85kDa-like	12179	0.29
chr11_104669483_104669764	2.37	CASP12	caspase 12 (gene/pseudogene)	99518	0.08
chr12_67107724_67108271	2.27	GRIP1	glutamate receptor interacting protein 1	35072	0.24
chr6_128580481_128581088	2.24	PTPRK	protein tyrosine phosphatase, receptor type, K	62542	0.14
chr6_149126816_149126995	2.22	UST	uronyl-2-sulfotransferase	58441	0.16
chr15_36693921_36694243	2.21	C15orf41	chromosome 15 open reading frame 41	177730	0.03
chr17_40263956_40264570	2.17	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	218	0.87
chr2_198702670_198703177	2.16	PLCL1	phospholipase C-like 1	27941	0.2
chr8_70180166_70180390	2.14	ENSG00000238808	.	157469	0.04
chr6_128799339_128799870	2.13	RP1-86D1.5		22068	0.14
chr6_37410804_37411085	2.11	CMTR1	cap methyltransferase 1	9948	0.21
chr2_212942952_212943169	2.10	ENSG00000221782	.	348024	0.01
chr9_128408983_128409218	2.09	MAPKAP1	mitogen-activated protein kinase associated protein 1	3596	0.32
chr1_88383945_88384194	2.01	ENSG00000199318	.	465013	0.01
chr17_17863409_17863570	1.99	TOM1L2	target of myb1-like 2 (chicken)	12222	0.15
chrX_25086022_25086209	1.97	ENSG00000240439	.	7059	0.28
chr5_6828115_6828430	1.97	ENSG00000200243	.	20303	0.27
chr15_58702506_58703018	1.97	LIPC	lipase, hepatic	6	0.98
chr1_174959503_174960178	1.96	ENSG00000252552	.	5821	0.15
chr12_121829638_121829987	1.95	ANAPC5	anaphase promoting complex subunit 5	7887	0.2
chr4_99560865_99561052	1.93	TSPAN5	tetraspanin 5	17828	0.22
chr3_159628787_159629360	1.90	SCHIP1	schwannomin interacting protein 1	58345	0.11
chr2_177000583_177000734	1.89	HOXD3	homeobox D3	1027	0.23
chr10_33775891_33776280	1.88	NRP1	neuropilin 1	150895	0.04
chr20_30358146_30358468	1.86	TPX2	TPX2, microtubule-associated	31233	0.11
chr6_106369868_106370019	1.82	ENSG00000200198	.	17695	0.28
chr1_111772526_111772677	1.82	CHI3L2	chitinase 3-like 2	159	0.94
chr17_78044749_78045392	1.80	CCDC40	coiled-coil domain containing 40	12346	0.15
chrX_13680418_13680616	1.77	TCEANC	transcription elongation factor A (SII) N-terminal and central domain containing	7103	0.2
chr10_31637499_31637650	1.77	RP11-192P3.5		15363	0.19
chr2_198703252_198703452	1.76	PLCL1	phospholipase C-like 1	28370	0.2
chr2_141868171_141868322	1.75	ENSG00000252015	.	56680	0.17
chr4_26398560_26398711	1.74	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	31707	0.23
chr3_114136122_114136315	1.73	ZBTB20-AS1	ZBTB20 antisense RNA 1	29702	0.18
chr7_45243750_45244089	1.73	RAMP3	receptor (G protein-coupled) activity modifying protein 3	46491	0.13
chr15_36623727_36623943	1.73	C15orf41	chromosome 15 open reading frame 41	247977	0.02
chr15_62916920_62917378	1.70	RP11-625H11.1	Uncharacterized protein	20231	0.19
chr16_14050687_14051311	1.69	CTD-2135D7.2		21507	0.22
chr12_113415975_113416207	1.69	OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	109	0.96
chr2_134484497_134484648	1.67	ENSG00000200708	.	130910	0.05
chr2_225822345_225822719	1.66	DOCK10	dedicator of cytokinesis 10	10750	0.28
chr9_35276443_35276716	1.66	AL160274.1	HCG17281; PRO0038; Uncharacterized protein	84683	0.07
chr12_88809886_88810316	1.66	ENSG00000199245	.	14118	0.29
chr11_108040783_108041103	1.65	NPAT	nuclear protein, ataxia-telangiectasia locus	8051	0.17
chr3_63937239_63937390	1.65	ATXN7	ataxin 7	16106	0.16
chr4_149137974_149138458	1.65	RP11-76G10.1		70594	0.13
chr10_100453757_100453908	1.65	HPS1	Hermansky-Pudlak syndrome 1	247149	0.02
chr11_67417906_67418392	1.63	ACY3	aspartoacylase (aminocyclase) 3	19	0.96
chr2_206849241_206849392	1.63	AC007679.3		4993	0.2
chr17_17531992_17532217	1.62	PEMT	phosphatidylethanolamine N-methyltransferase	37082	0.12
chr17_80339190_80339423	1.61	UTS2R	urotensin 2 receptor	7153	0.1
chr2_162566075_162566329	1.61	SLC4A10	solute carrier family 4, sodium bicarbonate transporter, member 10	85231	0.1
chr13_50726169_50726866	1.61	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	70210	0.1
chr2_216696276_216696459	1.61	ENSG00000212055	.	47275	0.18
chr11_32383224_32383375	1.60	WT1	Wilms tumor 1	38862	0.19
chr10_13382497_13382864	1.60	SEPHS1	selenophosphate synthetase 1	110	0.97
chr4_89520899_89521174	1.59	HERC3	HECT and RLD domain containing E3 ubiquitin protein ligase 3	5909	0.19
chr2_210654487_210655159	1.59	UNC80	unc-80 homolog (C. elegans)	18060	0.25
chr10_99444807_99445034	1.59	AVPI1	arginine vasopressin-induced 1	2160	0.25
chr2_183755742_183755893	1.58	ENSG00000207178	.	17248	0.19
chr4_138448087_138448238	1.57	PCDH18	protocadherin 18	5403	0.36
chr1_24469240_24469593	1.57	IL22RA1	interleukin 22 receptor, alpha 1	195	0.94
chr15_71115759_71115910	1.57	RP11-138H8.6		26275	0.14
chr5_158302177_158302618	1.57	CTD-2363C16.1		107617	0.07
chr13_102279386_102279657	1.56	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	29026	0.25
chr11_108095871_108096022	1.56	ATM	ataxia telangiectasia mutated	1141	0.41
chr3_191008228_191008379	1.56	UTS2B	urotensin 2B	8111	0.23
chr4_25333211_25333559	1.54	ZCCHC4	zinc finger, CCHC domain containing 4	1498	0.44
chr18_56106091_56106384	1.53	ENSG00000207778	.	12069	0.17
chr1_246117311_246117716	1.52	RP11-83A16.1		79340	0.11
chr14_81425715_81426140	1.51	CEP128	centrosomal protein 128kDa	79	0.98
chr11_65695547_65695843	1.50	DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)	8500	0.09
chr4_187761894_187762105	1.49	ENSG00000252382	.	16611	0.28
chr3_48100570_48100771	1.49	MAP4	microtubule-associated protein 4	29644	0.15
chr15_55973905_55974056	1.49	RP11-420M1.2		1397	0.45
chr5_176085830_176086097	1.48	TSPAN17	tetraspanin 17	11342	0.13
chr18_61646886_61647217	1.47	SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8	9	0.98
chr7_54972295_54972520	1.47	ENSG00000252054	.	38896	0.2
chr13_52338770_52339293	1.47	DHRS12	dehydrogenase/reductase (SDR family) member 12	39203	0.15
chr17_71548139_71548468	1.46	RP11-449L23.3		32318	0.17
chr7_15002566_15002796	1.45	DGKB	diacylglycerol kinase, beta 90kDa	11721	0.31
chr12_91971432_91971827	1.45	DCN	decorin	394729	0.01
chr18_40710046_40710304	1.45	RIT2	Ras-like without CAAX 2	14518	0.31
chr1_11000222_11000475	1.45	C1orf127	chromosome 1 open reading frame 127	7579	0.18
chr5_53765584_53765762	1.44	HSPB3	heat shock 27kDa protein 3	14228	0.25
chr18_26351468_26351619	1.44	ENSG00000251719	.	277041	0.02
chr4_154390309_154390666	1.43	KIAA0922	KIAA0922	2986	0.33
chr10_116157125_116157362	1.43	AFAP1L2	actin filament associated protein 1-like 2	6996	0.24
chr15_76578675_76579026	1.43	ETFA	electron-transfer-flavoprotein, alpha polypeptide	5982	0.24
chr16_47813458_47814031	1.42	PHKB	phosphorylase kinase, beta	83361	0.1
chr2_204780332_204780483	1.42	ICOS	inducible T-cell co-stimulator	21064	0.23
chr16_11352546_11352922	1.42	SOCS1	suppressor of cytokine signaling 1	2698	0.13
chr3_93743081_93743253	1.41	STX19	syntaxin 19	4287	0.18
chr21_28767417_28767751	1.41	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	428752	0.01
chr3_121151020_121151375	1.41	POLQ	polymerase (DNA directed), theta	113656	0.06
chr4_160170135_160170337	1.41	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	17797	0.23
chr2_226329396_226329663	1.41	NYAP2	neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2	55932	0.18
chr12_67748139_67748363	1.40	CAND1	cullin-associated and neddylation-dissociated 1	55499	0.18
chr17_38559088_38559385	1.40	ENSG00000222881	.	11646	0.11
chr4_143487028_143487271	1.39	INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	5327	0.36
chr2_43495897_43496225	1.39	AC010883.5		39349	0.17
chr8_10487827_10488180	1.38	RP1L1	retinitis pigmentosa 1-like 1	24609	0.14
chr6_134757108_134757519	1.38	SGK1	serum/glucocorticoid regulated kinase 1	118063	0.06
chr8_13363129_13363280	1.38	DLC1	deleted in liver cancer 1	6454	0.24
chr13_27262340_27262491	1.38	WASF3-AS1	WASF3 antisense RNA 1	46914	0.17
chr6_141647971_141648132	1.38	ENSG00000222764	.	159498	0.04
chr2_199639717_199640158	1.38	ENSG00000252511	.	208484	0.03
chr6_6005898_6006049	1.37	NRN1	neuritin 1	1227	0.56
chr4_4494063_4494282	1.37	STX18-IT1	STX18 intronic transcript 1 (non-protein coding)	10745	0.21
chr1_85645360_85645511	1.37	SYDE2	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	21294	0.16
chr12_40077019_40077550	1.37	C12orf40	chromosome 12 open reading frame 40	57299	0.13
chr18_66389023_66389655	1.36	TMX3	thioredoxin-related transmembrane protein 3	6804	0.21
chr12_120246787_120247132	1.36	CIT	citron (rho-interacting, serine/threonine kinase 21)	5772	0.26
chr13_40600523_40600674	1.35	ENSG00000212553	.	169234	0.03
chr1_89535774_89536043	1.34	GBP1	guanylate binding protein 1, interferon-inducible	4865	0.2
chr13_49832065_49832609	1.34	CDADC1	cytidine and dCMP deaminase domain containing 1	10153	0.23
chr7_76757802_76757953	1.34	CCDC146	coiled-coil domain containing 146	5943	0.23
chr5_139560716_139560896	1.34	CYSTM1	cysteine-rich transmembrane module containing 1	6579	0.15
chr8_122274743_122274894	1.33	ENSG00000221644	.	75686	0.12
chrX_56839017_56839464	1.33	ENSG00000204272	.	83548	0.1
chr10_134776117_134776455	1.33	TTC40	tetratricopeptide repeat domain 40	19959	0.23
chr3_67735991_67736422	1.33	SUCLG2	succinate-CoA ligase, GDP-forming, beta subunit	31168	0.25
chr13_105792322_105792542	1.32	DAOA	D-amino acid oxidase activator	326160	0.01
chr6_20681189_20681370	1.32	RP3-348I23.2		119646	0.06
chr20_25520737_25520958	1.32	NINL	ninein-like	45306	0.13
chr5_159354784_159354935	1.32	ADRA1B	adrenoceptor alpha 1B	11069	0.25
chr13_24540637_24541010	1.32	SPATA13	spermatogenesis associated 13	13121	0.19
chr1_220855036_220855222	1.32	C1orf115	chromosome 1 open reading frame 115	8058	0.2
chr5_55285831_55286061	1.32	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	4846	0.17
chr7_1116079_1116461	1.32	AC091729.7		2184	0.17
chrX_131467583_131467734	1.31	MBNL3	muscleblind-like splicing regulator 3	57330	0.15
chr1_208260069_208260332	1.30	PLXNA2	plexin A2	157465	0.04
chr9_17272633_17272784	1.30	CNTLN	centlein, centrosomal protein	137670	0.05
chr1_223070946_223071112	1.30	ENSG00000239054	.	14260	0.22
chr14_63944838_63945013	1.30	ENSG00000252463	.	433	0.7
chr3_187085927_187086158	1.29	RTP4	receptor (chemosensory) transporter protein 4	78	0.98
chr5_109443303_109443454	1.28	AC011366.3	Uncharacterized protein	224495	0.02
chr18_32609618_32610414	1.28	MAPRE2	microtubule-associated protein, RP/EB family, member 2	11308	0.29
chr13_43473650_43473814	1.28	EPSTI1	epithelial stromal interaction 1 (breast)	91635	0.09
chr3_114085665_114085816	1.28	ZBTB20-AS1	ZBTB20 antisense RNA 1	176	0.95
chr16_85585173_85585329	1.28	GSE1	Gse1 coiled-coil protein	59764	0.12
chr7_19802663_19802814	1.28	TMEM196	transmembrane protein 196	10079	0.22
chr11_28643392_28643616	1.28	ENSG00000222385	.	360438	0.01
chr6_16413526_16413976	1.27	ENSG00000265642	.	15003	0.28
chr13_102965778_102965929	1.27	FGF14-AS1	FGF14 antisense RNA 1	54036	0.15
chr4_164465492_164465704	1.27	ENSG00000264535	.	21154	0.2
chr15_96164396_96164547	1.26	ENSG00000222076	.	124562	0.06
chr11_104788706_104789238	1.26	RP11-693N9.2		8330	0.2
chr14_91305515_91305680	1.26	TTC7B	tetratricopeptide repeat domain 7B	22774	0.24
chr3_20084808_20085457	1.26	KAT2B	K(lysine) acetyltransferase 2B	3617	0.24
chr1_121200380_121200843	1.26	FCGR1B	Fc fragment of IgG, high affinity Ib, receptor (CD64)	264674	0.02
chr8_56919292_56919443	1.26	ENSG00000241997	.	15505	0.15
chr4_81487797_81488048	1.26	C4orf22	chromosome 4 open reading frame 22	230999	0.02
chr1_242108256_242108407	1.25	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma	54044	0.13
chr5_36071274_36071728	1.25	UGT3A2	UDP glycosyltransferase 3 family, polypeptide A2	4115	0.23
chr3_114103034_114103268	1.25	ZBTB20	zinc finger and BTB domain containing 20	663	0.71
chr17_30650967_30651144	1.25	C17orf75	chromosome 17 open reading frame 75	10507	0.14
chr5_21818159_21818310	1.24	ENSG00000221615	.	83914	0.11
chr1_70916763_70916914	1.24	CTH	cystathionase (cystathionine gamma-lyase)	39772	0.17
chr9_4111551_4111753	1.24	GLIS3	GLIS family zinc finger 3	33541	0.19
chr14_58820285_58820720	1.24	ARID4A	AT rich interactive domain 4A (RBP1-like)	22497	0.11
chr12_75783464_75783615	1.24	CAPS2	calcyphosine 2	1142	0.37
chr12_55385277_55385428	1.24	TESPA1	thymocyte expressed, positive selection associated 1	6822	0.23
chr14_50830018_50830334	1.24	CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	22329	0.16
chr5_108475290_108475441	1.24	ENSG00000206593	.	124724	0.06
chr7_15724850_15725001	1.23	MEOX2	mesenchyme homeobox 2	1512	0.49
chr7_70147090_70147241	1.23	AUTS2	autism susceptibility candidate 2	46960	0.21
chr4_75085563_75086012	1.23	AC093677.1	Uncharacterized protein	61702	0.1
chr1_67447187_67447690	1.23	MIER1	mesoderm induction early response 1, transcriptional regulator	51512	0.12
chr14_101315771_101315992	1.22	ENSG00000214548	.	236	0.69
chr9_90664194_90664345	1.22	ENSG00000271923	.	51019	0.15
chr8_109492835_109493105	1.22	EMC2	ER membrane protein complex subunit 2	30310	0.25
chr5_66833336_66833975	1.21	ENSG00000222939	.	73219	0.13
chr12_5294701_5295025	1.21	KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	141778	0.05
chr4_177738336_177738487	1.21	VEGFC	vascular endothelial growth factor C	24530	0.27
chr17_40264582_40264792	1.21	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	45	0.95
chr19_40333030_40333192	1.20	FBL	fibrillarin	1749	0.31
chr7_102383120_102383276	1.20	FAM185A	family with sequence similarity 185, member A	6277	0.2
chr11_1509066_1509217	1.20	MOB2	MOB kinase activator 2	1165	0.46
chrX_15800485_15800703	1.19	ZRSR2	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2	8001	0.2
chr2_205427585_205427736	1.19	PARD3B	par-3 family cell polarity regulator beta	16937	0.31
chr9_109876837_109877058	1.19	RP11-508N12.2		11678	0.29
chr2_41947627_41947876	1.19	ENSG00000252281	.	13766	0.28
chr3_44042054_44042245	1.19	ENSG00000252980	.	70430	0.12
chr7_95546340_95546491	1.19	DYNC1I1	dynein, cytoplasmic 1, intermediate chain 1	112819	0.07
chr3_12436703_12437398	1.19	PPARG	peroxisome proliferator-activated receptor gamma	44079	0.15
chr18_67614772_67614923	1.19	CD226	CD226 molecule	192	0.97
chr12_4136628_4136779	1.19	RP11-664D1.1		122317	0.06
chr8_144105408_144106241	1.19	LY6E	lymphocyte antigen 6 complex, locus E	5850	0.18
chr2_1028039_1028190	1.18	AC114808.3		35913	0.18
chr8_90845937_90846088	1.18	ENSG00000207359	.	67040	0.11
chr1_174383473_174383626	1.16	GPR52	G protein-coupled receptor 52	33663	0.21
chr3_60062120_60062271	1.16	NPCDR1	nasopharyngeal carcinoma, down-regulated 1	104612	0.08
chr2_97439727_97440064	1.16	CNNM4	cyclin M4	13256	0.14
chr11_107940892_107941191	1.16	ENSG00000200855	.	14599	0.17
chr3_187755166_187755324	1.16	LPP	LIM domain containing preferred translocation partner in lipoma	115827	0.06

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	2.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.4	1.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.3	1.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.3	1.0	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3	0.8	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.3	0.6	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3	0.8	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3	0.8	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.3	0.5	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.3	1.8	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.2	0.5	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.2	0.7	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.2	1.7	GO:0006032	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2	0.7	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	1.3	GO:0002860	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2	0.7	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.8	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.2	0.8	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.2	1.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2	0.6	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.2	0.8	GO:0045634	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.2	0.6	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2	0.7	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.2	0.4	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.2	0.5	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	0.7	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.2	0.5	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.2	0.8	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.2	0.7	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	0.5	GO:0072143	mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.2	2.2	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.2	0.6	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2	0.5	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.2	0.5	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2	0.5	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:0072600	protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1	0.6	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1	1.3	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1	0.3	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.3	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.3	GO:0090195	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1	0.1	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.1	0.4	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.3	GO:0048368	lateral mesoderm development(GO:0048368)
0.1	0.5	GO:0051503	adenine nucleotide transport(GO:0051503)
0.1	0.5	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.3	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.1	0.3	GO:0010159	specification of organ position(GO:0010159)
0.1	0.4	GO:0002913	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.5	GO:0001757	somite specification(GO:0001757)
0.1	0.5	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.1	0.4	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.4	GO:0046476	glycosylceramide biosynthetic process(GO:0046476)
0.1	0.5	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.4	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.1	0.5	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.1	GO:1901072	amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.1	0.6	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	1.2	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.2	GO:0014889	muscle atrophy(GO:0014889)
0.1	0.4	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.8	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.7	GO:0008356	asymmetric cell division(GO:0008356)
0.1	0.3	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.3	GO:0060539	diaphragm development(GO:0060539)
0.1	0.3	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.3	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.1	0.8	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.1	0.6	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.2	GO:2000050	regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.1	0.2	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.1	0.5	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.1	0.3	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1	0.3	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.1	0.3	GO:0071569	protein ufmylation(GO:0071569)
0.1	1.3	GO:0071445	obsolete cellular response to protein stimulus(GO:0071445)
0.1	0.3	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.1	0.3	GO:0060242	contact inhibition(GO:0060242)
0.1	0.2	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.4	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.1	0.4	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.1	0.4	GO:0071731	response to nitric oxide(GO:0071731)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.3	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.4	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1	0.3	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.5	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.3	GO:0071277	cellular response to calcium ion(GO:0071277)
0.1	0.5	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.1	0.3	GO:0010842	retina layer formation(GO:0010842)
0.1	0.7	GO:0000090	mitotic anaphase(GO:0000090)
0.1	0.2	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.2	GO:0060992	response to fungicide(GO:0060992)
0.1	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.1	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.1	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1	0.4	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.7	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.8	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.8	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.1	0.4	GO:0010455	positive regulation of cell fate commitment(GO:0010455)
0.1	0.1	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.1	0.3	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.1	0.4	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1	1.3	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.5	GO:0006477	protein sulfation(GO:0006477)
0.1	0.1	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1	0.3	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.1	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.3	GO:0071436	sodium ion export(GO:0071436)
0.1	0.3	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	1.5	GO:0070206	protein trimerization(GO:0070206)
0.1	0.3	GO:0032607	interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.1	0.3	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	0.3	GO:0006855	drug transmembrane transport(GO:0006855)
0.1	0.2	GO:0042415	norepinephrine metabolic process(GO:0042415)
0.1	0.2	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.4	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.1	0.6	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.2	GO:0060526	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	0.2	GO:0034444	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.1	0.2	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.1	0.3	GO:0032455	nerve growth factor processing(GO:0032455)
0.1	0.6	GO:0035082	axoneme assembly(GO:0035082)
0.1	0.5	GO:0016553	base conversion or substitution editing(GO:0016553)
0.1	0.4	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.2	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.3	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.1	GO:0060435	bronchiole development(GO:0060435)
0.1	0.4	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.1	0.1	GO:0021825	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:0006670	sphingosine metabolic process(GO:0006670)
0.1	0.2	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	0.4	GO:0043368	positive T cell selection(GO:0043368)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.3	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.1	0.2	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.1	0.1	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.1	0.3	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.2	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.1	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1	0.1	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.1	0.1	GO:0071481	cellular response to X-ray(GO:0071481)
0.1	0.2	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.2	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.1	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.3	GO:0006451	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1	1.1	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.3	GO:0032288	myelin assembly(GO:0032288)
0.1	0.3	GO:0060013	righting reflex(GO:0060013)
0.1	0.1	GO:0014029	neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1	0.1	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1	0.4	GO:0032099	negative regulation of appetite(GO:0032099)
0.1	0.2	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1	0.2	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.4	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.1	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1	0.7	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1	0.2	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.1	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.1	0.2	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.2	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.1	0.2	GO:0043587	tongue morphogenesis(GO:0043587)
0.1	0.2	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.1	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1	0.2	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.1	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.1	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1	0.1	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.1	0.2	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.3	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.1	0.2	GO:0030573	bile acid catabolic process(GO:0030573)
0.1	0.1	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.2	GO:0070670	response to interleukin-4(GO:0070670)
0.1	0.1	GO:0032641	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.2	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.4	GO:0009154	purine ribonucleotide catabolic process(GO:0009154)
0.1	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.1	GO:0034644	cellular response to UV(GO:0034644)
0.1	0.1	GO:0031063	regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.1	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.1	GO:0033158	regulation of protein import into nucleus, translocation(GO:0033158)
0.1	0.3	GO:0070527	platelet aggregation(GO:0070527)
0.1	0.4	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.4	GO:0031529	ruffle organization(GO:0031529)
0.1	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.1	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.2	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1	0.5	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.0	GO:0001779	natural killer cell differentiation(GO:0001779)
0.0	0.0	GO:2000193	positive regulation of fatty acid transport(GO:2000193)
0.0	0.1	GO:0042816	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.1	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.4	GO:0048821	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.0	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.0	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.2	GO:0046880	regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0	0.1	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.5	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.4	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.2	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.1	GO:0060581	ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0	0.0	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0	0.3	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.0	GO:0033088	regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.1	GO:0032095	regulation of response to food(GO:0032095)
0.0	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.4	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.2	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.2	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.0	0.1	GO:0060437	lung growth(GO:0060437)
0.0	0.1	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.5	GO:0070534	protein K63-linked ubiquitination(GO:0070534)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0090399	replicative senescence(GO:0090399)
0.0	0.1	GO:0032735	positive regulation of interleukin-12 production(GO:0032735)
0.0	0.1	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.2	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	0.1	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0071028	RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0	0.0	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.3	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0021548	pons development(GO:0021548) facial nucleus development(GO:0021754)
0.0	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.5	GO:1901186	positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.2	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.2	GO:0007512	adult heart development(GO:0007512)
0.0	0.0	GO:0043045	DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0	1.8	GO:0031295	lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0	0.5	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.0	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.0	0.1	GO:0060412	ventricular septum morphogenesis(GO:0060412)
0.0	0.1	GO:0060438	trachea development(GO:0060438)
0.0	0.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0015802	basic amino acid transport(GO:0015802)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0060391	regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.1	GO:0032790	ribosome disassembly(GO:0032790)
0.0	0.2	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0060693	regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0	0.8	GO:0060135	maternal process involved in female pregnancy(GO:0060135)
0.0	0.1	GO:0060676	ureteric bud formation(GO:0060676)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.0	GO:0042363	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0003214	cardiac left ventricle morphogenesis(GO:0003214)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0010107	potassium ion import(GO:0010107)
0.0	0.0	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0032429	regulation of phospholipase A2 activity(GO:0032429)
0.0	0.0	GO:0009415	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0	0.1	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0	0.3	GO:0001569	patterning of blood vessels(GO:0001569)
0.0	0.2	GO:0032653	regulation of interleukin-10 production(GO:0032653)
0.0	0.2	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.2	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.2	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.0	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.1	GO:0045349	interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.2	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.2	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0035411	catenin import into nucleus(GO:0035411) regulation of catenin import into nucleus(GO:0035412)
0.0	0.0	GO:0045992	negative regulation of embryonic development(GO:0045992)
0.0	0.0	GO:0061217	positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0071347	cellular response to interleukin-1(GO:0071347)
0.0	0.1	GO:0050686	negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0	0.2	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.1	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.0	GO:0060998	regulation of dendritic spine development(GO:0060998)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.3	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:0060907	positive regulation of macrophage cytokine production(GO:0060907)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.2	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.5	GO:0032011	ARF protein signal transduction(GO:0032011)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.2	GO:0021517	ventral spinal cord development(GO:0021517)
0.0	0.2	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.3	GO:0072523	purine-containing compound catabolic process(GO:0072523)
0.0	0.1	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.4	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.1	GO:0008634	obsolete negative regulation of survival gene product expression(GO:0008634)
0.0	0.4	GO:0016998	cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0	0.1	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0034650	cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0	0.1	GO:0002467	germinal center formation(GO:0002467)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0000462	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0	0.6	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0006531	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0043616	keratinocyte proliferation(GO:0043616)
0.0	0.1	GO:0021561	facial nerve development(GO:0021561) rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) preganglionic parasympathetic fiber development(GO:0021783) parasympathetic nervous system development(GO:0048486)
0.0	0.3	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.3	GO:0007530	sex determination(GO:0007530)
0.0	0.3	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.2	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.0	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.3	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.0	0.2	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.1	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.5	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.0	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.0	GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.7	GO:0006885	regulation of pH(GO:0006885)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0019374	galactolipid metabolic process(GO:0019374)
0.0	0.1	GO:0060761	negative regulation of response to cytokine stimulus(GO:0060761)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.0	GO:0048840	otolith development(GO:0048840)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.3	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.1	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.0	GO:0061383	trabecula formation(GO:0060343) bone trabecula formation(GO:0060346) trabecula morphogenesis(GO:0061383) bone trabecula morphogenesis(GO:0061430)
0.0	0.2	GO:0007520	syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0	0.2	GO:0043101	purine-containing compound salvage(GO:0043101)
0.0	0.3	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	1.6	GO:0051260	protein homooligomerization(GO:0051260)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.0	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	1.0	GO:0030198	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.0	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0035610	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0097480	synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0	0.1	GO:0031076	embryonic camera-type eye development(GO:0031076)
0.0	0.0	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.2	GO:0001706	endoderm formation(GO:0001706)
0.0	0.6	GO:0000725	double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0	0.0	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.2	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.2	GO:0045995	regulation of embryonic development(GO:0045995)
0.0	0.1	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
0.0	0.0	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.1	GO:0032924	activin receptor signaling pathway(GO:0032924)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.1	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.2	GO:0045026	plasma membrane fusion(GO:0045026)
0.0	0.1	GO:0001662	behavioral fear response(GO:0001662)
0.0	0.1	GO:0030903	notochord development(GO:0030903)
0.0	0.1	GO:0002027	regulation of heart rate(GO:0002027)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.0	GO:0032816	positive regulation of natural killer cell activation(GO:0032816)
0.0	0.1	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.0	0.1	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.0	GO:0009200	deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0	0.0	GO:0072044	collecting duct development(GO:0072044)
0.0	0.1	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.0	0.1	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	0.0	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.1	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.2	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0	0.1	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.0	GO:1903008	organelle disassembly(GO:1903008)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	0.0	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.3	GO:0017156	calcium ion regulated exocytosis(GO:0017156)
0.0	0.0	GO:0070849	response to epidermal growth factor(GO:0070849)
0.0	0.0	GO:0043129	surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0	0.3	GO:0022409	positive regulation of cell-cell adhesion(GO:0022409)
0.0	0.0	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0007635	chemosensory behavior(GO:0007635)
0.0	0.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.0	GO:0045060	negative thymic T cell selection(GO:0045060)
0.0	0.0	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.0	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.0	GO:0014065	phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0	0.0	GO:0045046	protein import into peroxisome membrane(GO:0045046)
0.0	0.1	GO:0002026	regulation of the force of heart contraction(GO:0002026)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.0	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.2	GO:0032963	collagen metabolic process(GO:0032963)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.0	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0000050	urea cycle(GO:0000050)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.0	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0021854	hypothalamus development(GO:0021854)
0.0	0.1	GO:0051775	response to redox state(GO:0051775)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0071503	response to heparin(GO:0071503)
0.0	0.1	GO:0010389	regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0014911	positive regulation of smooth muscle cell migration(GO:0014911)
0.0	0.1	GO:0030825	positive regulation of cGMP metabolic process(GO:0030825)
0.0	0.1	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
0.0	0.0	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0048048	embryonic eye morphogenesis(GO:0048048)
0.0	0.0	GO:0001821	histamine secretion(GO:0001821)
0.0	0.1	GO:0006544	glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.3	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0	0.0	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.0	GO:0051148	negative regulation of muscle cell differentiation(GO:0051148)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.0	GO:0010830	regulation of myotube differentiation(GO:0010830)
0.0	0.0	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.0	GO:0042516	regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0	0.0	GO:0007406	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.1	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.0	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0032309	icosanoid secretion(GO:0032309)
0.0	0.4	GO:0060271	cilium morphogenesis(GO:0060271)
0.0	0.2	GO:0031640	killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0	0.0	GO:0014904	myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0	0.0	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.1	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:1903299	regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0010390	histone monoubiquitination(GO:0010390)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.0	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.0	GO:0006657	CDP-choline pathway(GO:0006657)
0.0	0.1	GO:0033598	mammary gland epithelial cell proliferation(GO:0033598)
0.0	0.1	GO:0033619	membrane protein proteolysis(GO:0033619)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.0	GO:0006111	regulation of gluconeogenesis(GO:0006111)
0.0	0.0	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	1.6	GO:0005614	interstitial matrix(GO:0005614)
0.2	0.6	GO:0071438	invadopodium membrane(GO:0071438)
0.2	0.5	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.2	0.7	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.6	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.4	GO:0001652	granular component(GO:0001652)
0.1	1.4	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	1.0	GO:0008091	spectrin(GO:0008091)
0.1	0.3	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	1.1	GO:0016585	obsolete chromatin remodeling complex(GO:0016585)
0.1	0.5	GO:0031082	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1	0.4	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	2.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	0.4	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.4	GO:0033268	node of Ranvier(GO:0033268)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.2	GO:0000124	SAGA complex(GO:0000124)
0.1	0.5	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	0.5	GO:0002102	podosome(GO:0002102)
0.1	1.4	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.8	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	0.2	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.6	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.4	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.3	GO:0071778	obsolete WINAC complex(GO:0071778)
0.1	0.6	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.3	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0043218	compact myelin(GO:0043218)
0.0	0.2	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.2	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0030315	T-tubule(GO:0030315)
0.0	0.7	GO:0033276	transcription factor TFTC complex(GO:0033276)
0.0	1.7	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.0	GO:0005922	connexon complex(GO:0005922)
0.0	0.3	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.2	GO:0001739	sex chromatin(GO:0001739)
0.0	0.2	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.3	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.4	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.8	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.3	GO:0016012	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	1.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.1	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0033646	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.4	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.9	GO:0043195	terminal bouton(GO:0043195)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	1.8	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.3	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0030934	anchoring collagen complex(GO:0030934)
0.0	0.3	GO:0071565	nBAF complex(GO:0071565)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.4	GO:0031672	A band(GO:0031672)
0.0	0.2	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.2	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0030125	clathrin vesicle coat(GO:0030125)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	2.2	GO:0070160	bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.6	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.2	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.8	GO:0034704	calcium channel complex(GO:0034704)
0.0	1.2	GO:0015030	Cajal body(GO:0015030)
0.0	0.0	GO:0005871	kinesin complex(GO:0005871)
0.0	1.7	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:0001741	XY body(GO:0001741)
0.0	3.7	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.1	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0045178	basal part of cell(GO:0045178)
0.0	0.1	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.6	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.2	GO:0030894	replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0071546	pi-body(GO:0071546)
0.0	0.4	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.4	GO:0055037	recycling endosome(GO:0055037)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	1.0	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.4	GO:0045121	membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0042611	MHC protein complex(GO:0042611)
0.0	0.1	GO:0005921	gap junction(GO:0005921)
0.0	0.1	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.2	GO:0000178	exosome (RNase complex)(GO:0000178)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.5	GO:0005814	centriole(GO:0005814)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.1	GO:0001917	photoreceptor inner segment(GO:0001917)
0.0	0.2	GO:0031256	leading edge membrane(GO:0031256)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.3	GO:0016234	inclusion body(GO:0016234)
0.0	0.3	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	1.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0042599	lamellar body(GO:0042599)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.5	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	1.1	GO:0005795	Golgi stack(GO:0005795)
0.0	0.8	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	1.0	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	1.0	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.0	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.0	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.0	GO:0070852	cell body fiber(GO:0070852)
0.0	2.2	GO:0005874	microtubule(GO:0005874)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.1	GO:0045261	proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.0	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	6.5	GO:0005615	extracellular space(GO:0005615)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.3	1.4	GO:0030284	estrogen receptor activity(GO:0030284)
0.3	0.9	GO:0005113	patched binding(GO:0005113)
0.3	1.3	GO:0004046	aminoacylase activity(GO:0004046)
0.3	0.8	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.2	1.7	GO:0004568	chitinase activity(GO:0004568)
0.2	1.2	GO:0004904	interferon receptor activity(GO:0004904)
0.2	1.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2	0.8	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	2.0	GO:0034185	apolipoprotein binding(GO:0034185)
0.2	0.2	GO:0004339	glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.2	1.3	GO:0043274	phospholipase binding(GO:0043274)
0.2	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.5	GO:0035184	histone threonine kinase activity(GO:0035184)
0.2	1.2	GO:0030507	spectrin binding(GO:0030507)
0.2	0.5	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.1	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.6	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.4	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.7	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.4	GO:0050693	LBD domain binding(GO:0050693)
0.1	1.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.4	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.1	0.8	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.9	GO:0008494	translation activator activity(GO:0008494)
0.1	0.4	GO:0070052	collagen V binding(GO:0070052)
0.1	0.4	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.1	0.5	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.6	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.5	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.3	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1	0.3	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	0.5	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.1	0.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.6	GO:0005521	lamin binding(GO:0005521)
0.1	0.9	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1	0.3	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.5	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.1	0.7	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1	0.4	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.8	GO:0033613	activating transcription factor binding(GO:0033613)
0.1	0.4	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.3	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.5	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.5	GO:0019238	cyclohydrolase activity(GO:0019238)
0.1	0.2	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.1	0.5	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.1	1.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.1	0.3	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	3.1	GO:0005518	collagen binding(GO:0005518)
0.1	0.8	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.1	0.2	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	0.6	GO:0046870	cadmium ion binding(GO:0046870)
0.1	0.3	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.1	0.3	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.3	GO:0004340	glucokinase activity(GO:0004340)
0.1	0.9	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.1	0.2	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1	0.2	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.1	0.2	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.4	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.4	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.1	0.2	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.2	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.7	GO:0030276	clathrin binding(GO:0030276)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.3	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	0.3	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.3	GO:0034452	dynactin binding(GO:0034452)
0.1	0.3	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.1	1.2	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	0.2	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.8	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.1	0.4	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.3	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.2	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	1.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1	0.5	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.7	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.1	0.5	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1	0.4	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.5	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.2	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	1.6	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.1	0.5	GO:0046625	sphingolipid binding(GO:0046625)
0.1	0.2	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.7	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.1	0.2	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1	0.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.5	GO:0050780	dopamine receptor binding(GO:0050780)
0.1	0.2	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	0.2	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.3	GO:0042805	actinin binding(GO:0042805)
0.1	0.2	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.2	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1	0.8	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.2	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	0.2	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.5	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.3	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.7	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	1.2	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.4	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	3.0	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.2	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.5	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.4	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.4	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.3	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.5	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.4	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.4	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.1	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.5	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	1.3	GO:0017048	Rho GTPase binding(GO:0017048)
0.0	0.2	GO:0015250	water channel activity(GO:0015250)
0.0	0.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	2.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0048256	flap endonuclease activity(GO:0048256)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.4	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0044620	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0	0.6	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.4	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.7	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.3	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.3	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0008061	chitin binding(GO:0008061)
0.0	0.2	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0015193	L-proline transmembrane transporter activity(GO:0015193)
0.0	0.2	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0045159	myosin II binding(GO:0045159)
0.0	0.4	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:1901567	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.4	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0004396	hexokinase activity(GO:0004396)
0.0	0.1	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0070643	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0	0.3	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.6	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.3	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.3	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.2	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.3	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	2.0	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.1	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.3	GO:0032393	MHC class I receptor activity(GO:0032393)
0.0	0.3	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.5	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.9	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.0	0.2	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.4	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.2	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.4	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	5.9	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.3	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.3	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.4	GO:0001637	G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.2	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.5	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.2	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.0	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0008200	ion channel inhibitor activity(GO:0008200)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.0	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.4	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.3	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.6	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.0	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	1.7	GO:0008168	methyltransferase activity(GO:0008168)
0.0	0.1	GO:0080032	methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.4	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.0	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.2	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.2	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0016885	ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.4	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.0	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0042808	obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0	0.0	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.2	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.2	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0032395	MHC class II receptor activity(GO:0032395)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.0	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.0	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.2	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.0	GO:0051637	obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0	0.1	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.0	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.3	GO:0070851	growth factor receptor binding(GO:0070851)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.1	3.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	0.6	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.1	2.8	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	1.9	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	1.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	1.8	PID MYC PATHWAY	C-MYC pathway
0.1	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	1.2	PID CD40 PATHWAY	CD40/CD40L signaling
0.1	1.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	1.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.1	0.4	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.4	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.1	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.4	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.8	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.5	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.6	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.6	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.2	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.8	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	1.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	1.0	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.4	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.4	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.2	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	1.0	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.3	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.3	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.5	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.6	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.4	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.6	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	3.3	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.3	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	0.2	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.4	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.4	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.1	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.0	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.2	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.1	0.9	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.1	1.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	1.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.1	0.9	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.1	1.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	1.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	0.1	REACTOME SIGNALING BY GPCR	Genes involved in Signaling by GPCR
0.1	1.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.1	1.1	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	0.8	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.1	1.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	0.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	1.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	0.1	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1	1.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.1	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.5	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.1	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	1.0	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.7	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.0	REACTOME EICOSANOID LIGAND BINDING RECEPTORS	Genes involved in Eicosanoid ligand-binding receptors
0.0	0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	2.6	REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS	Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0	0.2	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.0	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.5	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.5	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.4	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME COSTIMULATION BY THE CD28 FAMILY	Genes involved in Costimulation by the CD28 family
0.0	1.6	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.7	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	1.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.4	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.5	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.3	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.6	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX	Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0	0.4	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH	Genes involved in NCAM signaling for neurite out-growth
0.0	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.5	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.6	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.2	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.1	REACTOME SHC MEDIATED CASCADE	Genes involved in SHC-mediated cascade
0.0	0.6	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.2	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	1.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.1	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.6	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.1	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.0	0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.1	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PI	Genes involved in Acyl chain remodelling of PI
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.0	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.1	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.4	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	1.3	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.4	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes

Results for IRF2_STAT2_IRF8_IRF1

Z-value: 6.52

Motif logo

Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IRF2_STAT2_IRF8_IRF1 motif across conditions

Conditions sorted by the z-value of the IRF2_STAT2_IRF8_IRF1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF2_STAT2_IRF8_IRF1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: