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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for IRF2_STAT2_IRF8_IRF1

Z-value: 6.52

Motif logo

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Transcription factors associated with IRF2_STAT2_IRF8_IRF1

Gene Symbol Gene ID Gene Info
ENSG00000168310.6 IRF2
ENSG00000170581.9 STAT2
ENSG00000140968.6 IRF8
ENSG00000125347.9 IRF1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
IRF1chr5_131833252_13183340368370.1432350.412.8e-01Click!
IRF1chr5_131831030_13183122946390.155983-0.383.1e-01Click!
IRF1chr5_131822252_13182240330100.181720-0.225.8e-01Click!
IRF1chr5_131823400_13182355118620.2547580.215.8e-01Click!
IRF1chr5_131831286_13183190851070.151976-0.206.1e-01Click!
IRF2chr4_185327944_185328095117250.207489-0.703.5e-02Click!
IRF2chr4_185435112_185435265394540.1515520.655.8e-02Click!
IRF2chr4_185279118_185279269605510.108707-0.646.3e-02Click!
IRF2chr4_185278861_185279012608080.108202-0.608.7e-02Click!
IRF2chr4_185276503_185276684631510.103678-0.521.6e-01Click!
IRF8chr16_85887206_85887357451280.102513-0.881.9e-03Click!
IRF8chr16_85947812_85947963320.983661-0.521.5e-01Click!
IRF8chr16_85887601_85887752447330.103616-0.521.5e-01Click!
IRF8chr16_85942617_85942768980.977364-0.452.2e-01Click!
IRF8chr16_86020719_86020879728800.1095940.452.3e-01Click!
STAT2chr12_56753180_567533316030.5126660.422.6e-01Click!
STAT2chr12_56754222_567544084050.670120-0.196.2e-01Click!
STAT2chr12_56753471_567539111670.8817350.156.9e-01Click!

Activity of the IRF2_STAT2_IRF8_IRF1 motif across conditions

Conditions sorted by the z-value of the IRF2_STAT2_IRF8_IRF1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_29485980_29486219 2.87 RP11-142O6.1

25899
0.14
chr18_22239957_22240733 2.86 HRH4
histamine receptor H4
199652
0.02
chr5_81763009_81763176 2.61 ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
161926
0.04
chr18_42366702_42366923 2.54 SETBP1
SET binding protein 1
89683
0.1
chr6_118985728_118985996 2.52 CEP85L
centrosomal protein 85kDa-like
12179
0.29
chr11_104669483_104669764 2.37 CASP12
caspase 12 (gene/pseudogene)
99518
0.08
chr12_67107724_67108271 2.27 GRIP1
glutamate receptor interacting protein 1
35072
0.24
chr6_128580481_128581088 2.24 PTPRK
protein tyrosine phosphatase, receptor type, K
62542
0.14
chr6_149126816_149126995 2.22 UST
uronyl-2-sulfotransferase
58441
0.16
chr15_36693921_36694243 2.21 C15orf41
chromosome 15 open reading frame 41
177730
0.03
chr17_40263956_40264570 2.17 DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
218
0.87
chr2_198702670_198703177 2.16 PLCL1
phospholipase C-like 1
27941
0.2
chr8_70180166_70180390 2.14 ENSG00000238808
.
157469
0.04
chr6_128799339_128799870 2.13 RP1-86D1.5

22068
0.14
chr6_37410804_37411085 2.11 CMTR1
cap methyltransferase 1
9948
0.21
chr2_212942952_212943169 2.10 ENSG00000221782
.
348024
0.01
chr9_128408983_128409218 2.09 MAPKAP1
mitogen-activated protein kinase associated protein 1
3596
0.32
chr1_88383945_88384194 2.01 ENSG00000199318
.
465013
0.01
chr17_17863409_17863570 1.99 TOM1L2
target of myb1-like 2 (chicken)
12222
0.15
chrX_25086022_25086209 1.97 ENSG00000240439
.
7059
0.28
chr5_6828115_6828430 1.97 ENSG00000200243
.
20303
0.27
chr15_58702506_58703018 1.97 LIPC
lipase, hepatic
6
0.98
chr1_174959503_174960178 1.96 ENSG00000252552
.
5821
0.15
chr12_121829638_121829987 1.95 ANAPC5
anaphase promoting complex subunit 5
7887
0.2
chr4_99560865_99561052 1.93 TSPAN5
tetraspanin 5
17828
0.22
chr3_159628787_159629360 1.90 SCHIP1
schwannomin interacting protein 1
58345
0.11
chr2_177000583_177000734 1.89 HOXD3
homeobox D3
1027
0.23
chr10_33775891_33776280 1.88 NRP1
neuropilin 1
150895
0.04
chr20_30358146_30358468 1.86 TPX2
TPX2, microtubule-associated
31233
0.11
chr6_106369868_106370019 1.82 ENSG00000200198
.
17695
0.28
chr1_111772526_111772677 1.82 CHI3L2
chitinase 3-like 2
159
0.94
chr17_78044749_78045392 1.80 CCDC40
coiled-coil domain containing 40
12346
0.15
chrX_13680418_13680616 1.77 TCEANC
transcription elongation factor A (SII) N-terminal and central domain containing
7103
0.2
chr10_31637499_31637650 1.77 RP11-192P3.5

15363
0.19
chr2_198703252_198703452 1.76 PLCL1
phospholipase C-like 1
28370
0.2
chr2_141868171_141868322 1.75 ENSG00000252015
.
56680
0.17
chr4_26398560_26398711 1.74 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
31707
0.23
chr3_114136122_114136315 1.73 ZBTB20-AS1
ZBTB20 antisense RNA 1
29702
0.18
chr7_45243750_45244089 1.73 RAMP3
receptor (G protein-coupled) activity modifying protein 3
46491
0.13
chr15_36623727_36623943 1.73 C15orf41
chromosome 15 open reading frame 41
247977
0.02
chr15_62916920_62917378 1.70 RP11-625H11.1
Uncharacterized protein
20231
0.19
chr16_14050687_14051311 1.69 CTD-2135D7.2

21507
0.22
chr12_113415975_113416207 1.69 OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
109
0.96
chr2_134484497_134484648 1.67 ENSG00000200708
.
130910
0.05
chr2_225822345_225822719 1.66 DOCK10
dedicator of cytokinesis 10
10750
0.28
chr9_35276443_35276716 1.66 AL160274.1
HCG17281; PRO0038; Uncharacterized protein
84683
0.07
chr12_88809886_88810316 1.66 ENSG00000199245
.
14118
0.29
chr11_108040783_108041103 1.65 NPAT
nuclear protein, ataxia-telangiectasia locus
8051
0.17
chr3_63937239_63937390 1.65 ATXN7
ataxin 7
16106
0.16
chr4_149137974_149138458 1.65 RP11-76G10.1

70594
0.13
chr10_100453757_100453908 1.65 HPS1
Hermansky-Pudlak syndrome 1
247149
0.02
chr11_67417906_67418392 1.63 ACY3
aspartoacylase (aminocyclase) 3
19
0.96
chr2_206849241_206849392 1.63 AC007679.3

4993
0.2
chr17_17531992_17532217 1.62 PEMT
phosphatidylethanolamine N-methyltransferase
37082
0.12
chr17_80339190_80339423 1.61 UTS2R
urotensin 2 receptor
7153
0.1
chr2_162566075_162566329 1.61 SLC4A10
solute carrier family 4, sodium bicarbonate transporter, member 10
85231
0.1
chr13_50726169_50726866 1.61 DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
70210
0.1
chr2_216696276_216696459 1.61 ENSG00000212055
.
47275
0.18
chr11_32383224_32383375 1.60 WT1
Wilms tumor 1
38862
0.19
chr10_13382497_13382864 1.60 SEPHS1
selenophosphate synthetase 1
110
0.97
chr4_89520899_89521174 1.59 HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
5909
0.19
chr2_210654487_210655159 1.59 UNC80
unc-80 homolog (C. elegans)
18060
0.25
chr10_99444807_99445034 1.59 AVPI1
arginine vasopressin-induced 1
2160
0.25
chr2_183755742_183755893 1.58 ENSG00000207178
.
17248
0.19
chr4_138448087_138448238 1.57 PCDH18
protocadherin 18
5403
0.36
chr1_24469240_24469593 1.57 IL22RA1
interleukin 22 receptor, alpha 1
195
0.94
chr15_71115759_71115910 1.57 RP11-138H8.6

26275
0.14
chr5_158302177_158302618 1.57 CTD-2363C16.1

107617
0.07
chr13_102279386_102279657 1.56 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
29026
0.25
chr11_108095871_108096022 1.56 ATM
ataxia telangiectasia mutated
1141
0.41
chr3_191008228_191008379 1.56 UTS2B
urotensin 2B
8111
0.23
chr4_25333211_25333559 1.54 ZCCHC4
zinc finger, CCHC domain containing 4
1498
0.44
chr18_56106091_56106384 1.53 ENSG00000207778
.
12069
0.17
chr1_246117311_246117716 1.52 RP11-83A16.1

79340
0.11
chr14_81425715_81426140 1.51 CEP128
centrosomal protein 128kDa
79
0.98
chr11_65695547_65695843 1.50 DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
8500
0.09
chr4_187761894_187762105 1.49 ENSG00000252382
.
16611
0.28
chr3_48100570_48100771 1.49 MAP4
microtubule-associated protein 4
29644
0.15
chr15_55973905_55974056 1.49 RP11-420M1.2

1397
0.45
chr5_176085830_176086097 1.48 TSPAN17
tetraspanin 17
11342
0.13
chr18_61646886_61647217 1.47 SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
9
0.98
chr7_54972295_54972520 1.47 ENSG00000252054
.
38896
0.2
chr13_52338770_52339293 1.47 DHRS12
dehydrogenase/reductase (SDR family) member 12
39203
0.15
chr17_71548139_71548468 1.46 RP11-449L23.3

32318
0.17
chr7_15002566_15002796 1.45 DGKB
diacylglycerol kinase, beta 90kDa
11721
0.31
chr12_91971432_91971827 1.45 DCN
decorin
394729
0.01
chr18_40710046_40710304 1.45 RIT2
Ras-like without CAAX 2
14518
0.31
chr1_11000222_11000475 1.45 C1orf127
chromosome 1 open reading frame 127
7579
0.18
chr5_53765584_53765762 1.44 HSPB3
heat shock 27kDa protein 3
14228
0.25
chr18_26351468_26351619 1.44 ENSG00000251719
.
277041
0.02
chr4_154390309_154390666 1.43 KIAA0922
KIAA0922
2986
0.33
chr10_116157125_116157362 1.43 AFAP1L2
actin filament associated protein 1-like 2
6996
0.24
chr15_76578675_76579026 1.43 ETFA
electron-transfer-flavoprotein, alpha polypeptide
5982
0.24
chr16_47813458_47814031 1.42 PHKB
phosphorylase kinase, beta
83361
0.1
chr2_204780332_204780483 1.42 ICOS
inducible T-cell co-stimulator
21064
0.23
chr16_11352546_11352922 1.42 SOCS1
suppressor of cytokine signaling 1
2698
0.13
chr3_93743081_93743253 1.41 STX19
syntaxin 19
4287
0.18
chr21_28767417_28767751 1.41 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
428752
0.01
chr3_121151020_121151375 1.41 POLQ
polymerase (DNA directed), theta
113656
0.06
chr4_160170135_160170337 1.41 RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
17797
0.23
chr2_226329396_226329663 1.41 NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
55932
0.18
chr12_67748139_67748363 1.40 CAND1
cullin-associated and neddylation-dissociated 1
55499
0.18
chr17_38559088_38559385 1.40 ENSG00000222881
.
11646
0.11
chr4_143487028_143487271 1.39 INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
5327
0.36
chr2_43495897_43496225 1.39 AC010883.5

39349
0.17
chr8_10487827_10488180 1.38 RP1L1
retinitis pigmentosa 1-like 1
24609
0.14
chr6_134757108_134757519 1.38 SGK1
serum/glucocorticoid regulated kinase 1
118063
0.06
chr8_13363129_13363280 1.38 DLC1
deleted in liver cancer 1
6454
0.24
chr13_27262340_27262491 1.38 WASF3-AS1
WASF3 antisense RNA 1
46914
0.17
chr6_141647971_141648132 1.38 ENSG00000222764
.
159498
0.04
chr2_199639717_199640158 1.38 ENSG00000252511
.
208484
0.03
chr6_6005898_6006049 1.37 NRN1
neuritin 1
1227
0.56
chr4_4494063_4494282 1.37 STX18-IT1
STX18 intronic transcript 1 (non-protein coding)
10745
0.21
chr1_85645360_85645511 1.37 SYDE2
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
21294
0.16
chr12_40077019_40077550 1.37 C12orf40
chromosome 12 open reading frame 40
57299
0.13
chr18_66389023_66389655 1.36 TMX3
thioredoxin-related transmembrane protein 3
6804
0.21
chr12_120246787_120247132 1.36 CIT
citron (rho-interacting, serine/threonine kinase 21)
5772
0.26
chr13_40600523_40600674 1.35 ENSG00000212553
.
169234
0.03
chr1_89535774_89536043 1.34 GBP1
guanylate binding protein 1, interferon-inducible
4865
0.2
chr13_49832065_49832609 1.34 CDADC1
cytidine and dCMP deaminase domain containing 1
10153
0.23
chr7_76757802_76757953 1.34 CCDC146
coiled-coil domain containing 146
5943
0.23
chr5_139560716_139560896 1.34 CYSTM1
cysteine-rich transmembrane module containing 1
6579
0.15
chr8_122274743_122274894 1.33 ENSG00000221644
.
75686
0.12
chrX_56839017_56839464 1.33 ENSG00000204272
.
83548
0.1
chr10_134776117_134776455 1.33 TTC40
tetratricopeptide repeat domain 40
19959
0.23
chr3_67735991_67736422 1.33 SUCLG2
succinate-CoA ligase, GDP-forming, beta subunit
31168
0.25
chr13_105792322_105792542 1.32 DAOA
D-amino acid oxidase activator
326160
0.01
chr6_20681189_20681370 1.32 RP3-348I23.2

119646
0.06
chr20_25520737_25520958 1.32 NINL
ninein-like
45306
0.13
chr5_159354784_159354935 1.32 ADRA1B
adrenoceptor alpha 1B
11069
0.25
chr13_24540637_24541010 1.32 SPATA13
spermatogenesis associated 13
13121
0.19
chr1_220855036_220855222 1.32 C1orf115
chromosome 1 open reading frame 115
8058
0.2
chr5_55285831_55286061 1.32 IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
4846
0.17
chr7_1116079_1116461 1.32 AC091729.7

2184
0.17
chrX_131467583_131467734 1.31 MBNL3
muscleblind-like splicing regulator 3
57330
0.15
chr1_208260069_208260332 1.30 PLXNA2
plexin A2
157465
0.04
chr9_17272633_17272784 1.30 CNTLN
centlein, centrosomal protein
137670
0.05
chr1_223070946_223071112 1.30 ENSG00000239054
.
14260
0.22
chr14_63944838_63945013 1.30 ENSG00000252463
.
433
0.7
chr3_187085927_187086158 1.29 RTP4
receptor (chemosensory) transporter protein 4
78
0.98
chr5_109443303_109443454 1.28 AC011366.3
Uncharacterized protein
224495
0.02
chr18_32609618_32610414 1.28 MAPRE2
microtubule-associated protein, RP/EB family, member 2
11308
0.29
chr13_43473650_43473814 1.28 EPSTI1
epithelial stromal interaction 1 (breast)
91635
0.09
chr3_114085665_114085816 1.28 ZBTB20-AS1
ZBTB20 antisense RNA 1
176
0.95
chr16_85585173_85585329 1.28 GSE1
Gse1 coiled-coil protein
59764
0.12
chr7_19802663_19802814 1.28 TMEM196
transmembrane protein 196
10079
0.22
chr11_28643392_28643616 1.28 ENSG00000222385
.
360438
0.01
chr6_16413526_16413976 1.27 ENSG00000265642
.
15003
0.28
chr13_102965778_102965929 1.27 FGF14-AS1
FGF14 antisense RNA 1
54036
0.15
chr4_164465492_164465704 1.27 ENSG00000264535
.
21154
0.2
chr15_96164396_96164547 1.26 ENSG00000222076
.
124562
0.06
chr11_104788706_104789238 1.26 RP11-693N9.2

8330
0.2
chr14_91305515_91305680 1.26 TTC7B
tetratricopeptide repeat domain 7B
22774
0.24
chr3_20084808_20085457 1.26 KAT2B
K(lysine) acetyltransferase 2B
3617
0.24
chr1_121200380_121200843 1.26 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
264674
0.02
chr8_56919292_56919443 1.26 ENSG00000241997
.
15505
0.15
chr4_81487797_81488048 1.26 C4orf22
chromosome 4 open reading frame 22
230999
0.02
chr1_242108256_242108407 1.25 MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
54044
0.13
chr5_36071274_36071728 1.25 UGT3A2
UDP glycosyltransferase 3 family, polypeptide A2
4115
0.23
chr3_114103034_114103268 1.25 ZBTB20
zinc finger and BTB domain containing 20
663
0.71
chr17_30650967_30651144 1.25 C17orf75
chromosome 17 open reading frame 75
10507
0.14
chr5_21818159_21818310 1.24 ENSG00000221615
.
83914
0.11
chr1_70916763_70916914 1.24 CTH
cystathionase (cystathionine gamma-lyase)
39772
0.17
chr9_4111551_4111753 1.24 GLIS3
GLIS family zinc finger 3
33541
0.19
chr14_58820285_58820720 1.24 ARID4A
AT rich interactive domain 4A (RBP1-like)
22497
0.11
chr12_75783464_75783615 1.24 CAPS2
calcyphosine 2
1142
0.37
chr12_55385277_55385428 1.24 TESPA1
thymocyte expressed, positive selection associated 1
6822
0.23
chr14_50830018_50830334 1.24 CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
22329
0.16
chr5_108475290_108475441 1.24 ENSG00000206593
.
124724
0.06
chr7_15724850_15725001 1.23 MEOX2
mesenchyme homeobox 2
1512
0.49
chr7_70147090_70147241 1.23 AUTS2
autism susceptibility candidate 2
46960
0.21
chr4_75085563_75086012 1.23 AC093677.1
Uncharacterized protein
61702
0.1
chr1_67447187_67447690 1.23 MIER1
mesoderm induction early response 1, transcriptional regulator
51512
0.12
chr14_101315771_101315992 1.22 ENSG00000214548
.
236
0.69
chr9_90664194_90664345 1.22 ENSG00000271923
.
51019
0.15
chr8_109492835_109493105 1.22 EMC2
ER membrane protein complex subunit 2
30310
0.25
chr5_66833336_66833975 1.21 ENSG00000222939
.
73219
0.13
chr12_5294701_5295025 1.21 KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
141778
0.05
chr4_177738336_177738487 1.21 VEGFC
vascular endothelial growth factor C
24530
0.27
chr17_40264582_40264792 1.21 DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
45
0.95
chr19_40333030_40333192 1.20 FBL
fibrillarin
1749
0.31
chr7_102383120_102383276 1.20 FAM185A
family with sequence similarity 185, member A
6277
0.2
chr11_1509066_1509217 1.20 MOB2
MOB kinase activator 2
1165
0.46
chrX_15800485_15800703 1.19 ZRSR2
zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
8001
0.2
chr2_205427585_205427736 1.19 PARD3B
par-3 family cell polarity regulator beta
16937
0.31
chr9_109876837_109877058 1.19 RP11-508N12.2

11678
0.29
chr2_41947627_41947876 1.19 ENSG00000252281
.
13766
0.28
chr3_44042054_44042245 1.19 ENSG00000252980
.
70430
0.12
chr7_95546340_95546491 1.19 DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
112819
0.07
chr3_12436703_12437398 1.19 PPARG
peroxisome proliferator-activated receptor gamma
44079
0.15
chr18_67614772_67614923 1.19 CD226
CD226 molecule
192
0.97
chr12_4136628_4136779 1.19 RP11-664D1.1

122317
0.06
chr8_144105408_144106241 1.19 LY6E
lymphocyte antigen 6 complex, locus E
5850
0.18
chr2_1028039_1028190 1.18 AC114808.3

35913
0.18
chr8_90845937_90846088 1.18 ENSG00000207359
.
67040
0.11
chr1_174383473_174383626 1.16 GPR52
G protein-coupled receptor 52
33663
0.21
chr3_60062120_60062271 1.16 NPCDR1
nasopharyngeal carcinoma, down-regulated 1
104612
0.08
chr2_97439727_97440064 1.16 CNNM4
cyclin M4
13256
0.14
chr11_107940892_107941191 1.16 ENSG00000200855
.
14599
0.17
chr3_187755166_187755324 1.16 LPP
LIM domain containing preferred translocation partner in lipoma
115827
0.06

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of IRF2_STAT2_IRF8_IRF1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.4 1.4 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.3 1.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.3 1.0 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.3 0.8 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.3 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.3 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.3 0.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.3 0.5 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.3 1.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 0.5 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.2 0.7 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.2 1.7 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 0.7 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.2 1.3 GO:0002860 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.2 0.7 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.8 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.2 0.8 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.2 1.0 GO:0032875 regulation of DNA endoreduplication(GO:0032875) negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.2 0.6 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.2 0.8 GO:0045634 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.2 0.6 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2 0.7 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.2 0.4 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.2 0.5 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.7 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.2 0.5 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.8 GO:0006925 inflammatory cell apoptotic process(GO:0006925)
0.2 0.7 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.2 0.5 GO:0072143 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.2 2.2 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.2 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.2 0.5 GO:0070874 negative regulation of glycogen metabolic process(GO:0070874)
0.2 0.5 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.2 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0072600 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 0.6 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628) positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.3 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0006154 adenosine catabolic process(GO:0006154)
0.1 0.3 GO:0090195 chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1 0.1 GO:0060737 prostate gland morphogenetic growth(GO:0060737)
0.1 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.5 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 0.5 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.3 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.1 0.3 GO:0010159 specification of organ position(GO:0010159)
0.1 0.4 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.5 GO:0001757 somite specification(GO:0001757)
0.1 0.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.1 0.4 GO:0046476 glycosylceramide biosynthetic process(GO:0046476)
0.1 0.5 GO:0032825 regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.5 GO:0060363 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.4 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.1 GO:1901072 amino sugar catabolic process(GO:0046348) glucosamine-containing compound catabolic process(GO:1901072)
0.1 0.6 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 1.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 0.2 GO:0014889 muscle atrophy(GO:0014889)
0.1 0.4 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.8 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.7 GO:0008356 asymmetric cell division(GO:0008356)
0.1 0.3 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 0.3 GO:0060539 diaphragm development(GO:0060539)
0.1 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.1 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.1 0.2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.3 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.1 0.2 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.1 0.5 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 0.3 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1 0.3 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.1 1.3 GO:0071445 obsolete cellular response to protein stimulus(GO:0071445)
0.1 0.3 GO:0003207 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.1 0.3 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.4 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.4 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.3 GO:0070102 interleukin-6-mediated signaling pathway(GO:0070102)
0.1 0.3 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.3 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.1 0.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.5 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 0.5 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.7 GO:0000090 mitotic anaphase(GO:0000090)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0060992 response to fungicide(GO:0060992)
0.1 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.7 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 0.8 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.8 GO:0030204 chondroitin sulfate metabolic process(GO:0030204)
0.1 0.4 GO:0010455 positive regulation of cell fate commitment(GO:0010455)
0.1 0.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.1 0.3 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 1.3 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.1 0.5 GO:0006477 protein sulfation(GO:0006477)
0.1 0.1 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.1 0.3 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.1 GO:0072338 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.3 GO:0071436 sodium ion export(GO:0071436)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 1.5 GO:0070206 protein trimerization(GO:0070206)
0.1 0.3 GO:0032607 interferon-alpha production(GO:0032607) regulation of interferon-alpha production(GO:0032647) positive regulation of interferon-alpha production(GO:0032727)
0.1 0.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.1 0.3 GO:0006855 drug transmembrane transport(GO:0006855)
0.1 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 0.4 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.1 0.6 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.2 GO:0060526 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 0.2 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.1 0.2 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.2 GO:0006573 valine metabolic process(GO:0006573)
0.1 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.1 0.6 GO:0035082 axoneme assembly(GO:0035082)
0.1 0.5 GO:0016553 base conversion or substitution editing(GO:0016553)
0.1 0.4 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 0.2 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1 0.3 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.1 0.1 GO:0021825 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 0.2 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.1 GO:0032656 regulation of interleukin-13 production(GO:0032656)
0.1 0.4 GO:0043368 positive T cell selection(GO:0043368)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.3 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.2 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.2 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.1 GO:0032966 negative regulation of collagen biosynthetic process(GO:0032966)
0.1 0.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0046469 platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.2 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.1 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 1.1 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.3 GO:0032288 myelin assembly(GO:0032288)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.1 GO:0014029 neural crest formation(GO:0014029) neural crest cell fate commitment(GO:0014034)
0.1 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.4 GO:0032099 negative regulation of appetite(GO:0032099)
0.1 0.2 GO:2001234 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.1 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.4 GO:0008595 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 0.1 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.1 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.2 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.1 0.2 GO:0021831 embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.1 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.2 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.1 0.2 GO:0043587 tongue morphogenesis(GO:0043587)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.1 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100)
0.1 0.2 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.1 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.1 GO:0051458 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.1 0.2 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.3 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.2 GO:0032506 cytokinetic process(GO:0032506)
0.1 0.2 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1 0.2 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.1 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.1 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.4 GO:0009154 purine ribonucleotide catabolic process(GO:0009154)
0.1 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.1 0.1 GO:0034644 cellular response to UV(GO:0034644)
0.1 0.1 GO:0031063 regulation of histone deacetylation(GO:0031063) positive regulation of histone deacetylation(GO:0031065)
0.1 0.3 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.1 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.1 0.3 GO:0070527 platelet aggregation(GO:0070527)
0.1 0.4 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.4 GO:0031529 ruffle organization(GO:0031529)
0.1 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.1 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.2 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.5 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.0 GO:0001779 natural killer cell differentiation(GO:0001779)
0.0 0.0 GO:2000193 positive regulation of fatty acid transport(GO:2000193)
0.0 0.1 GO:0042816 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.1 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.1 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0033522 histone H2A ubiquitination(GO:0033522)
0.0 0.4 GO:0048821 erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.0 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.0 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.0 0.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0046880 regulation of follicle-stimulating hormone secretion(GO:0046880)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0 0.5 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.2 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.0 0.1 GO:0060581 ventral spinal cord interneuron differentiation(GO:0021514) ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
0.0 0.0 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.3 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.0 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:0032095 regulation of response to food(GO:0032095)
0.0 0.2 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.2 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.5 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.2 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0032735 positive regulation of interleukin-12 production(GO:0032735)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.2 GO:0050746 regulation of lipoprotein metabolic process(GO:0050746)
0.0 0.1 GO:0048935 peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0071028 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.0 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.3 GO:0031000 response to caffeine(GO:0031000)
0.0 0.0 GO:0021548 pons development(GO:0021548) facial nucleus development(GO:0021754)
0.0 0.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.5 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.0 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.0 1.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.5 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0032096 negative regulation of response to food(GO:0032096)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0060412 ventricular septum morphogenesis(GO:0060412)
0.0 0.1 GO:0060438 trachea development(GO:0060438)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0060391 regulation of SMAD protein import into nucleus(GO:0060390) positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0007567 parturition(GO:0007567)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.0 0.8 GO:0060135 maternal process involved in female pregnancy(GO:0060135)
0.0 0.1 GO:0060676 ureteric bud formation(GO:0060676)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.0 GO:0042363 vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.0 GO:0009415 response to water deprivation(GO:0009414) response to water(GO:0009415)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.3 GO:0001569 patterning of blood vessels(GO:0001569)
0.0 0.2 GO:0032653 regulation of interleukin-10 production(GO:0032653)
0.0 0.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.2 GO:0046174 polyol catabolic process(GO:0046174)
0.0 0.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:0045349 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.2 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.0 GO:0035411 catenin import into nucleus(GO:0035411) regulation of catenin import into nucleus(GO:0035412)
0.0 0.0 GO:0045992 negative regulation of embryonic development(GO:0045992)
0.0 0.0 GO:0061217 positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.1 GO:0050686 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.2 GO:0045822 negative regulation of heart contraction(GO:0045822)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.0 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.3 GO:0090659 adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0 0.1 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.2 GO:0021517 ventral spinal cord development(GO:0021517)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.3 GO:0072523 purine-containing compound catabolic process(GO:0072523)
0.0 0.1 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0 0.4 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.1 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0034650 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0 0.1 GO:0002467 germinal center formation(GO:0002467)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0000462 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479) RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.6 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0006531 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0043616 keratinocyte proliferation(GO:0043616)
0.0 0.1 GO:0021561 facial nerve development(GO:0021561) rhombomere 4 development(GO:0021570) cranial nerve structural organization(GO:0021604) facial nerve morphogenesis(GO:0021610) facial nerve structural organization(GO:0021612) preganglionic parasympathetic fiber development(GO:0021783) parasympathetic nervous system development(GO:0048486)
0.0 0.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385) microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.1 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.3 GO:0007530 sex determination(GO:0007530)
0.0 0.3 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.0 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0009067 aspartate family amino acid biosynthetic process(GO:0009067)
0.0 0.2 GO:0050432 catecholamine secretion(GO:0050432)
0.0 0.1 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.0 GO:0033240 positive regulation of cellular amine metabolic process(GO:0033240)
0.0 0.0 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.7 GO:0006885 regulation of pH(GO:0006885)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0019374 galactolipid metabolic process(GO:0019374)
0.0 0.1 GO:0060761 negative regulation of response to cytokine stimulus(GO:0060761)
0.0 0.1 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.1 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0 0.0 GO:0048840 otolith development(GO:0048840)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0017158 regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0 0.1 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.0 GO:0061383 trabecula formation(GO:0060343) bone trabecula formation(GO:0060346) trabecula morphogenesis(GO:0061383) bone trabecula morphogenesis(GO:0061430)
0.0 0.2 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.2 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.3 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.6 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.0 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.0 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 1.0 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.1 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.1 GO:0035610 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0097480 synaptic vesicle transport(GO:0048489) synaptic vesicle localization(GO:0097479) establishment of synaptic vesicle localization(GO:0097480)
0.0 0.1 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 0.0 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.0 0.2 GO:0001706 endoderm formation(GO:0001706)
0.0 0.6 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.0 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.2 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.4 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.2 GO:0045995 regulation of embryonic development(GO:0045995)
0.0 0.1 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0032924 activin receptor signaling pathway(GO:0032924)
0.0 0.0 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.1 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.0 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0007350 blastoderm segmentation(GO:0007350)
0.0 0.2 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.1 GO:0001662 behavioral fear response(GO:0001662)
0.0 0.1 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0035121 obsolete tail morphogenesis(GO:0035121)
0.0 0.0 GO:0032816 positive regulation of natural killer cell activation(GO:0032816)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0046629 gamma-delta T cell activation(GO:0046629)
0.0 0.0 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.0 GO:0072044 collecting duct development(GO:0072044)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.0 GO:0055022 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.1 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0001660 fever generation(GO:0001660)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.0 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.0 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792) double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.1 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.0 GO:1903008 organelle disassembly(GO:1903008)
0.0 0.1 GO:0043278 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 0.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.0 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.0 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 0.0 GO:0070849 response to epidermal growth factor(GO:0070849)
0.0 0.0 GO:0043129 surfactant homeostasis(GO:0043129) chemical homeostasis within a tissue(GO:0048875)
0.0 0.3 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.0 0.0 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.0 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.0 GO:0031427 response to methotrexate(GO:0031427)
0.0 0.0 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.0 GO:0018119 protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.0 GO:0032094 response to food(GO:0032094)
0.0 0.0 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.0 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.0 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.0 0.1 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.0 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.2 GO:0032963 collagen metabolic process(GO:0032963)
0.0 0.0 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.0 GO:0000050 urea cycle(GO:0000050)
0.0 0.1 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.0 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.0 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.1 GO:0021854 hypothalamus development(GO:0021854)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0055015 ventricular cardiac muscle cell development(GO:0055015)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:0071503 response to heparin(GO:0071503)
0.0 0.1 GO:0010389 regulation of G2/M transition of mitotic cell cycle(GO:0010389) regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.0 0.1 GO:0030825 positive regulation of cGMP metabolic process(GO:0030825)
0.0 0.1 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.0 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.0 GO:0048048 embryonic eye morphogenesis(GO:0048048)
0.0 0.0 GO:0001821 histamine secretion(GO:0001821)
0.0 0.1 GO:0006544 glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.3 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.0 0.0 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0051148 negative regulation of muscle cell differentiation(GO:0051148)
0.0 0.0 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.0 GO:0010830 regulation of myotube differentiation(GO:0010830)
0.0 0.0 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.0 GO:0042516 regulation of tyrosine phosphorylation of Stat3 protein(GO:0042516)
0.0 0.0 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.1 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.0 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0032309 icosanoid secretion(GO:0032309)
0.0 0.4 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.2 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.0 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.0 GO:2000758 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.0 GO:1903299 regulation of glucokinase activity(GO:0033131) positive regulation of glucokinase activity(GO:0033133) regulation of hexokinase activity(GO:1903299) positive regulation of hexokinase activity(GO:1903301)
0.0 0.0 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0033598 mammary gland epithelial cell proliferation(GO:0033598)
0.0 0.1 GO:0033619 membrane protein proteolysis(GO:0033619)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.0 0.0 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 1.6 GO:0005614 interstitial matrix(GO:0005614)
0.2 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.2 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.2 0.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 1.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 1.1 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.1 0.5 GO:0031082 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.1 0.4 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.4 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.2 GO:0000124 SAGA complex(GO:0000124)
0.1 0.5 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 0.2 GO:0031211 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 0.3 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0043218 compact myelin(GO:0043218)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0030315 T-tubule(GO:0030315)
0.0 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.7 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.4 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.8 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.3 GO:0016012 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0033646 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.2 GO:0042598 obsolete vesicular fraction(GO:0042598)
0.0 0.2 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.4 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.2 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 1.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 2.2 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.8 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.0 GO:0005871 kinesin complex(GO:0005871)
0.0 1.7 GO:0060076 excitatory synapse(GO:0060076)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 3.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.1 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0045178 basal part of cell(GO:0045178)
0.0 0.1 GO:0033150 cytoskeletal calyx(GO:0033150)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.6 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0030681 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.2 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.0 GO:0071546 pi-body(GO:0071546)
0.0 0.4 GO:0019861 obsolete flagellum(GO:0019861)
0.0 0.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 1.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.1 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.5 GO:0005814 centriole(GO:0005814)
0.0 0.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0031256 leading edge membrane(GO:0031256)
0.0 0.0 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 0.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 1.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.5 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 1.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 1.0 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.0 GO:0070852 cell body fiber(GO:0070852)
0.0 2.2 GO:0005874 microtubule(GO:0005874)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 6.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.3 1.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.3 0.9 GO:0005113 patched binding(GO:0005113)
0.3 1.3 GO:0004046 aminoacylase activity(GO:0004046)
0.3 0.8 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 1.7 GO:0004568 chitinase activity(GO:0004568)
0.2 1.2 GO:0004904 interferon receptor activity(GO:0004904)
0.2 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 0.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 2.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 0.2 GO:0004339 glucan 1,4-alpha-glucosidase activity(GO:0004339)
0.2 1.3 GO:0043274 phospholipase binding(GO:0043274)
0.2 0.5 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.5 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 1.2 GO:0030507 spectrin binding(GO:0030507)
0.2 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.6 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.1 0.4 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.7 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.1 0.4 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.1 0.5 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.5 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 0.4 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.1 0.6 GO:0005521 lamin binding(GO:0005521)
0.1 0.9 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.8 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 0.4 GO:0004064 arylesterase activity(GO:0004064)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.1 0.8 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.1 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 0.6 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.3 GO:0004083 bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1 0.3 GO:0004340 glucokinase activity(GO:0004340)
0.1 0.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.1 0.2 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.7 GO:0030276 clathrin binding(GO:0030276)
0.1 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.3 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.3 GO:0034452 dynactin binding(GO:0034452)
0.1 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 1.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.2 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.3 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 1.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.7 GO:0003711 obsolete transcription elongation regulator activity(GO:0003711)
0.1 0.5 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.1 0.4 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.5 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.7 GO:0016986 obsolete transcription initiation factor activity(GO:0016986)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.5 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0042805 actinin binding(GO:0042805)
0.1 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.2 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.1 0.8 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 3.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.2 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.5 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.3 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.3 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.6 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.0 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.7 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0045159 myosin II binding(GO:0045159)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0004396 hexokinase activity(GO:0004396)
0.0 0.1 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.0 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.3 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.5 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.0 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 5.9 GO:0030528 obsolete transcription regulator activity(GO:0030528)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.4 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.1 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.0 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451)
0.0 0.4 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.6 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.0 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.7 GO:0008168 methyltransferase activity(GO:0008168)
0.0 0.1 GO:0080032 methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.4 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.0 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.0 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.2 GO:0008483 transaminase activity(GO:0008483)
0.0 0.1 GO:0016885 ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0 0.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.1 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.6 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.0 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.0 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.0 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.0 GO:0042808 obsolete neuronal Cdc2-like kinase binding(GO:0042808)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.0 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.0 GO:0051637 obsolete Gram-positive bacterial cell surface binding(GO:0051637)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.0 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.3 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 3.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.6 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.9 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 0.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 1.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.1 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.6 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.5 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.2 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.2 0.2 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.3 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.1 0.9 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 1.0 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME SIGNALING BY GPCR Genes involved in Signaling by GPCR
0.1 1.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 1.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.8 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 0.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.1 REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.1 1.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.1 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.1 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.0 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 2.6 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.2 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.5 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.5 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.2 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 0.1 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.1 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.3 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.4 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes