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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for IRF6_IRF4_IRF5

Z-value: 3.40

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Transcription factors associated with IRF6_IRF4_IRF5

Gene Symbol	Gene ID	Gene Info
IRF6 Ensembl NCBI GeneCards UniProt	ENSG00000117595.6	interferon regulatory factor 6
IRF4 Ensembl NCBI GeneCards UniProt	ENSG00000137265.10	interferon regulatory factor 4
IRF5 Ensembl NCBI GeneCards UniProt	ENSG00000128604.14	interferon regulatory factor 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_447061_447243	IRF4	55413	0.149832	0.65	5.8e-02	Click!
chr6_452886_453044	IRF4	61226	0.134483	0.58	1.0e-01	Click!
chr6_447789_448067	IRF4	56189	0.147707	0.57	1.1e-01	Click!
chr6_393916_394099	IRF4	2268	0.421932	0.55	1.3e-01	Click!
chr6_447624_447775	IRF4	55960	0.148332	0.45	2.2e-01	Click!
chr7_128584447_128584598	IRF5	3796	0.194286	-0.75	2.0e-02	Click!
chr7_128581950_128582101	IRF5	1299	0.399606	-0.60	8.9e-02	Click!
chr7_128580024_128580175	IRF5	161	0.944824	-0.59	9.6e-02	Click!
chr7_128573598_128573749	IRF5	3993	0.186613	-0.56	1.2e-01	Click!
chr7_128573173_128573372	IRF5	4394	0.180415	0.42	2.6e-01	Click!
chr1_209975427_209975724	IRF6	64	0.963723	-0.75	2.1e-02	Click!
chr1_209989675_209989826	IRF6	10285	0.145420	-0.69	4.0e-02	Click!
chr1_209989180_209989331	IRF6	9790	0.146096	-0.43	2.5e-01	Click!
chr1_209981772_209981923	IRF6	2382	0.224791	-0.34	3.7e-01	Click!
chr1_209977891_209978042	IRF6	1423	0.336270	-0.33	3.8e-01	Click!

Activity of the IRF6_IRF4_IRF5 motif across conditions

Conditions sorted by the z-value of the IRF6_IRF4_IRF5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_240739354_240740022	2.34	RP11-467I20.6		14360	0.2
chr16_14448667_14448906	1.89	ENSG00000199130	.	45644	0.14
chr3_114913699_114913850	1.73	ZBTB20	zinc finger and BTB domain containing 20	47656	0.2
chr12_28406339_28406704	1.66	CCDC91	coiled-coil domain containing 91	3137	0.33
chr4_75263884_75264078	1.63	EREG	epiregulin	33121	0.14
chr15_23810426_23810697	1.51	MKRN3	makorin ring finger protein 3	107	0.96
chr2_235399576_235400049	1.49	ARL4C	ADP-ribosylation factor-like 4C	5432	0.35
chr6_44900994_44901181	1.48	SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	22160	0.28
chr18_77157446_77157699	1.41	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	1347	0.51
chr7_70229502_70229653	1.37	AUTS2	autism susceptibility candidate 2	322	0.95
chr4_123499477_123499728	1.36	IL21-AS1	IL21 antisense RNA 1	40536	0.16
chr3_140985738_140985907	1.31	ACPL2	acid phosphatase-like 2	4366	0.29
chr11_82873492_82873814	1.28	PCF11	PCF11 cleavage and polyadenylation factor subunit	5452	0.18
chr2_86079968_86080395	1.27	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	14596	0.17
chr6_152504718_152504928	1.26	SYNE1	spectrin repeat containing, nuclear envelope 1	15324	0.29
chr9_89563961_89564112	1.21	GAS1	growth arrest-specific 1	1932	0.5
chr17_38483011_38483310	1.21	RARA	retinoic acid receptor, alpha	8623	0.11
chr1_120685462_120685613	1.20	ENSG00000207149	.	15975	0.24
chr1_67235326_67235808	1.18	TCTEX1D1	Tctex1 domain containing 1	17424	0.16
chr10_11905696_11905980	1.14	PROSER2	proline and serine-rich protein 2	5805	0.22
chr4_126541327_126541478	1.14	FAT4	FAT atypical cadherin 4	226311	0.02
chr21_36346415_36346697	1.13	RUNX1	runt-related transcription factor 1	74906	0.12
chr14_91817282_91817687	1.11	ENSG00000265856	.	17427	0.21
chr7_140075788_140076381	1.10	ENSG00000238868	.	618	0.63
chr11_65197238_65197524	1.09	ENSG00000245532	.	14548	0.11
chr5_175560458_175560649	1.08	FAM153B	family with sequence similarity 153, member B	48644	0.12
chr13_27998392_27998614	1.08	GTF3A	general transcription factor IIIA	178	0.94
chr22_36044436_36045027	1.05	APOL6	apolipoprotein L, 6	289	0.9
chr12_12658847_12659363	1.05	DUSP16	dual specificity phosphatase 16	14954	0.24
chr13_31348514_31348665	1.03	ALOX5AP	arachidonate 5-lipoxygenase-activating protein	38944	0.19
chr10_63809082_63810748	1.02	ARID5B	AT rich interactive domain 5B (MRF1-like)	945	0.69
chr19_12807522_12807697	1.01	FBXW9	F-box and WD repeat domain containing 9	152	0.87
chr8_142244970_142245137	1.00	SLC45A4	solute carrier family 45, member 4	4606	0.17
chr12_111325655_111325806	0.99	MYL2	myosin, light chain 2, regulatory, cardiac, slow	32649	0.18
chr1_101186979_101187209	0.99	VCAM1	vascular cell adhesion molecule 1	1774	0.47
chr18_60173458_60173677	0.97	ZCCHC2	zinc finger, CCHC domain containing 2	16673	0.25
chr4_120970917_120971140	0.95	RP11-679C8.2		17085	0.21
chr13_49832065_49832609	0.94	CDADC1	cytidine and dCMP deaminase domain containing 1	10153	0.23
chr2_70510251_70510402	0.94	SNRPG	small nuclear ribonucleoprotein polypeptide G	9582	0.12
chr10_133879422_133879820	0.94	JAKMIP3	Janus kinase and microtubule interacting protein 3	38554	0.18
chrX_149647092_149647284	0.93	MAMLD1	mastermind-like domain containing 1	7908	0.23
chr4_184949529_184949975	0.92	STOX2	storkhead box 2	27274	0.21
chr5_160974470_160974682	0.92	GABRB2	gamma-aminobutyric acid (GABA) A receptor, beta 2	554	0.86
chr13_43662113_43662459	0.91	DNAJC15	DnaJ (Hsp40) homolog, subfamily C, member 15	64947	0.14
chr4_122103316_122103738	0.90	ENSG00000252183	.	10531	0.22
chr1_184020441_184020753	0.90	TSEN15	TSEN15 tRNA splicing endonuclease subunit	214	0.95
chr1_168408925_168409115	0.89	ENSG00000207974	.	64258	0.12
chr13_111212240_111212402	0.89	RAB20	RAB20, member RAS oncogene family	1759	0.4
chr5_134374502_134374924	0.89	PITX1	paired-like homeodomain 1	4210	0.23
chr3_143566573_143567346	0.89	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	341	0.94
chr10_33775891_33776280	0.89	NRP1	neuropilin 1	150895	0.04
chr4_187643852_187644133	0.87	FAT1	FAT atypical cadherin 1	1017	0.68
chr2_112194089_112194240	0.87	ENSG00000266139	.	115496	0.07
chr2_204718048_204718377	0.86	CTLA4	cytotoxic T-lymphocyte-associated protein 4	14297	0.24
chr18_51750054_51750321	0.86	MBD2	methyl-CpG binding domain protein 2	800	0.56
chr1_197170699_197171135	0.86	CRB1	crumbs homolog 1 (Drosophila)	325	0.84
chr17_57237692_57237843	0.85	PRR11	proline rich 11	4660	0.11
chr10_102897939_102898090	0.83	RP11-31L23.3		1454	0.29
chr2_158301478_158301629	0.83	CYTIP	cytohesin 1 interacting protein	899	0.62
chr14_22962091_22962242	0.82	TRAJ51	T cell receptor alpha joining 51 (pseudogene)	5995	0.11
chr6_16421411_16421759	0.82	ENSG00000265642	.	7169	0.31
chr4_38525398_38525945	0.82	RP11-617D20.1		100525	0.07
chr6_105903581_105903732	0.81	PREP	prolyl endopeptidase	52697	0.17
chr2_199236589_199236791	0.81	ENSG00000252511	.	194763	0.03
chr1_88383945_88384194	0.80	ENSG00000199318	.	465013	0.01
chr17_6659349_6659686	0.80	XAF1	XIAP associated factor 1	131	0.95
chr1_150207180_150207436	0.79	ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	282	0.8
chr15_89248242_89248620	0.79	ISG20	interferon stimulated exonuclease gene 20kDa	66247	0.09
chr10_105419847_105420526	0.79	SH3PXD2A	SH3 and PX domains 2A	1276	0.44
chr11_47736997_47737222	0.79	AGBL2	ATP/GTP binding protein-like 2	168	0.93
chr12_9801609_9802018	0.79	RP11-705C15.4		1208	0.34
chr1_214455022_214455452	0.78	SMYD2	SET and MYND domain containing 2	661	0.81
chr6_12232816_12233088	0.78	EDN1	endothelin 1	57644	0.15
chr4_90220151_90220996	0.78	GPRIN3	GPRIN family member 3	8588	0.31
chr7_92347129_92347835	0.78	ENSG00000206763	.	16354	0.24
chrX_10318787_10318938	0.77	ENSG00000222133	.	134123	0.05
chr4_18059171_18059382	0.77	LCORL	ligand dependent nuclear receptor corepressor-like	35777	0.23
chr7_12250106_12250418	0.77	TMEM106B	transmembrane protein 106B	605	0.85
chr11_102187585_102188027	0.77	BIRC3	baculoviral IAP repeat containing 3	420	0.82
chr1_61745103_61745254	0.76	NFIA	nuclear factor I/A	72944	0.12
chr7_23221931_23222164	0.76	NUPL2	nucleoporin like 2	364	0.87
chr10_77531854_77532472	0.76	C10orf11	chromosome 10 open reading frame 11	10356	0.22
chr17_16319716_16320012	0.76	RP11-138I1.2		139	0.9
chr2_75938390_75938541	0.76	GCFC2	GC-rich sequence DNA-binding factor 2	350	0.86
chr8_99974349_99974596	0.76	OSR2	odd-skipped related transciption factor 2	13852	0.16
chr11_35061934_35062494	0.75	PDHX	pyruvate dehydrogenase complex, component X	62883	0.1
chr2_235362717_235362976	0.75	ARL4C	ADP-ribosylation factor-like 4C	42398	0.22
chr13_43148946_43149238	0.75	TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	732	0.81
chr2_11244414_11244565	0.74	C2orf50	chromosome 2 open reading frame 50	28690	0.19
chr21_47404119_47404503	0.74	COL6A1	collagen, type VI, alpha 1	2660	0.29
chr10_52177910_52178479	0.74	AC069547.2	Uncharacterized protein	25428	0.18
chr12_46062870_46063096	0.74	ARID2	AT rich interactive domain 2 (ARID, RFX-like)	60465	0.15
chrX_110338714_110339180	0.73	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	641	0.84
chrX_40014424_40014731	0.73	BCOR	BCL6 corepressor	8695	0.31
chr3_149253180_149253340	0.72	ENSG00000252581	.	9842	0.2
chr11_122561703_122562257	0.72	ENSG00000239079	.	35039	0.17
chr9_129916828_129917272	0.72	ANGPTL2	angiopoietin-like 2	31888	0.16
chr5_32583768_32584065	0.72	SUB1	SUB1 homolog (S. cerevisiae)	1689	0.49
chr11_616129_616280	0.71	IRF7	interferon regulatory factor 7	205	0.85
chr16_11352546_11352922	0.71	SOCS1	suppressor of cytokine signaling 1	2698	0.13
chr5_80444015_80444393	0.71	CTD-2193P3.2		33533	0.2
chr10_115141660_115142454	0.70	ENSG00000238380	.	28873	0.24
chr15_65187803_65188133	0.70	ENSG00000264929	.	4470	0.17
chr12_94136325_94136823	0.70	RP11-887P2.5		4975	0.26
chr2_87813697_87813848	0.69	RP11-1399P15.1		36219	0.21
chr6_106369868_106370019	0.69	ENSG00000200198	.	17695	0.28
chr5_5419342_5419575	0.69	KIAA0947	KIAA0947	3349	0.39
chr4_57666032_57666418	0.69	ENSG00000240545	.	5417	0.17
chr9_90664194_90664345	0.69	ENSG00000271923	.	51019	0.15
chr7_154996931_154997229	0.68	AC099552.4	Uncharacterized protein	6934	0.22
chr21_25801249_25801648	0.68	ENSG00000232512	.	671997	0.0
chr16_56677548_56677767	0.68	MT1DP	metallothionein 1D, pseudogene	20	0.93
chrY_15815919_15816489	0.68	TMSB4Y	thymosin beta 4, Y-linked	757	0.72
chr19_16437481_16437804	0.68	KLF2	Kruppel-like factor 2	1991	0.24
chr4_183413334_183413747	0.68	TENM3	teneurin transmembrane protein 3	43388	0.17
chr3_105088175_105088464	0.68	ALCAM	activated leukocyte cell adhesion molecule	2132	0.49
chr13_24540637_24541010	0.68	SPATA13	spermatogenesis associated 13	13121	0.19
chr17_8125726_8126160	0.67	CTC1	CTS telomere maintenance complex component 1	6780	0.09
chr12_102878022_102878367	0.67	IGF1	insulin-like growth factor 1 (somatomedin C)	3771	0.37
chr6_2854275_2854463	0.66	ENSG00000266750	.	28	0.98
chr1_8740967_8741199	0.66	RERE	arginine-glutamic acid dipeptide (RE) repeats	22195	0.23
chr12_6736731_6736882	0.66	LPAR5	lysophosphatidic acid receptor 5	4009	0.1
chr10_63662030_63662797	0.66	ARID5B	AT rich interactive domain 5B (MRF1-like)	1354	0.53
chr2_240302618_240303103	0.66	HDAC4	histone deacetylase 4	19783	0.17
chr10_93971165_93971316	0.65	ENSG00000221042	.	7177	0.19
chr16_66587034_66587357	0.65	CKLF-CMTM1	CKLF-CMTM1 readthrough	643	0.3
chr6_152504280_152504471	0.65	SYNE1	spectrin repeat containing, nuclear envelope 1	14876	0.29
chr3_138297162_138297368	0.65	CEP70	centrosomal protein 70kDa	13533	0.23
chr8_117396611_117396811	0.65	ENSG00000264815	.	97123	0.09
chr2_175496475_175496626	0.65	WIPF1	WAS/WASL interacting protein family, member 1	2757	0.3
chr6_68769904_68770108	0.65	ENSG00000266675	.	433325	0.01
chr15_40234807_40235047	0.65	ENSG00000238564	.	7980	0.15
chr11_9555045_9555196	0.65	ZNF143	zinc finger protein 143	21076	0.14
chr5_138720842_138721347	0.65	SLC23A1	solute carrier family 23 (ascorbic acid transporter), member 1	852	0.41
chr4_109086470_109087224	0.64	LEF1	lymphoid enhancer-binding factor 1	610	0.72
chr9_94668432_94668861	0.64	ROR2	receptor tyrosine kinase-like orphan receptor 2	42516	0.2
chr7_134103559_134103710	0.64	AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)	40260	0.18
chr13_28696488_28696678	0.64	PAN3-AS1	PAN3 antisense RNA 1	15747	0.17
chr4_71860383_71860569	0.64	DCK	deoxycytidine kinase	1121	0.6
chrX_84258496_84258805	0.64	APOOL	apolipoprotein O-like	182	0.97
chr21_42797993_42798388	0.64	MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	22	0.98
chr2_203037053_203037344	0.64	AC079354.5		6916	0.17
chr13_103244434_103244624	0.64	LINC00555	long intergenic non-protein coding RNA 555	2366	0.3
chrX_47092850_47093029	0.63	USP11	ubiquitin specific peptidase 11	148	0.93
chr15_58702506_58703018	0.63	LIPC	lipase, hepatic	6	0.98
chr5_158302177_158302618	0.63	CTD-2363C16.1		107617	0.07
chr7_48220574_48220725	0.63	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13	9592	0.28
chr10_77302555_77302706	0.63	ENSG00000207583	.	9586	0.26
chr17_43227716_43227867	0.63	HEXIM1	hexamethylene bis-acetamide inducible 1	3107	0.13
chr7_43798511_43798848	0.63	BLVRA	biliverdin reductase A	393	0.87
chr19_11159843_11160026	0.63	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	9577	0.14
chr12_105776449_105776971	0.63	C12orf75	chromosome 12 open reading frame 75	52064	0.13
chr2_204774653_204775027	0.63	ICOS	inducible T-cell co-stimulator	26631	0.21
chr3_69299099_69299578	0.62	FRMD4B	FERM domain containing 4B	42874	0.18
chr5_101999981_102000371	0.62	PAM	peptidylglycine alpha-amidating monooxygenase	89509	0.09
chr5_156618387_156618538	0.62	ITK	IL2-inducible T-cell kinase	10625	0.13
chr10_112116341_112116492	0.62	SMNDC1	survival motor neuron domain containing 1	51707	0.13
chr2_137084742_137084949	0.62	ENSG00000251976	.	63057	0.15
chr5_42992858_42993045	0.62	CTD-2035E11.3		25580	0.15
chr7_25301159_25301310	0.62	ENSG00000202233	.	3041	0.32
chr1_11000222_11000475	0.61	C1orf127	chromosome 1 open reading frame 127	7579	0.18
chr13_110431229_110431380	0.61	IRS2	insulin receptor substrate 2	7611	0.28
chr7_148823548_148823892	0.61	ZNF398	zinc finger protein 398	212	0.53
chr13_101170059_101170210	0.61	PCCA	propionyl CoA carboxylase, alpha polypeptide	2453	0.27
chr9_32526354_32526543	0.61	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	126	0.96
chrX_78668281_78668612	0.61	ITM2A	integral membrane protein 2A	45397	0.21
chr3_71538892_71539043	0.61	ENSG00000221264	.	52273	0.14
chr12_93830509_93830660	0.61	UBE2N	ubiquitin-conjugating enzyme E2N	4448	0.18
chr13_74806763_74806914	0.61	ENSG00000206617	.	56513	0.16
chr15_29562179_29562586	0.61	NDNL2	necdin-like 2	349	0.91
chr15_65590258_65590471	0.61	ENSG00000199568	.	1975	0.23
chr3_107807562_107807961	0.60	CD47	CD47 molecule	2100	0.46
chr2_240143439_240143590	0.60	HDAC4	histone deacetylase 4	30762	0.15
chr3_66533915_66534066	0.60	LRIG1	leucine-rich repeats and immunoglobulin-like domains 1	17366	0.29
chr2_128168319_128168706	0.60	PROC	protein C (inactivator of coagulation factors Va and VIIIa)	7491	0.16
chr19_16705198_16705410	0.60	CTD-3222D19.5		6508	0.09
chr1_115809994_115810145	0.59	RP4-663N10.1		15586	0.26
chrX_63425910_63426161	0.59	AMER1	APC membrane recruitment protein 1	411	0.85
chr5_91377820_91377974	0.59	ENSG00000264489	.	363847	0.01
chr6_108582659_108583044	0.59	SNX3	sorting nexin 3	387	0.81
chr14_81425715_81426140	0.59	CEP128	centrosomal protein 128kDa	79	0.98
chr1_230202248_230202508	0.59	GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	578	0.81
chr3_192610752_192611244	0.59	MB21D2	Mab-21 domain containing 2	24952	0.25
chr12_4140087_4140409	0.58	RP11-664D1.1		125862	0.05
chr22_23486968_23487119	0.58	RTDR1	rhabdoid tumor deletion region gene 1	165	0.78
chr19_15403974_15404125	0.58	BRD4	bromodomain containing 4	12787	0.18
chr10_129925339_129925490	0.58	MKI67	marker of proliferation Ki-67	765	0.78
chrY_8803913_8804064	0.58	AC007967.3		29723	0.26
chr2_233951599_233951825	0.58	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	26523	0.17
chr10_6626003_6626633	0.57	PRKCQ	protein kinase C, theta	4055	0.36
chr4_2847126_2847293	0.57	ADD1	adducin 1 (alpha)	1332	0.45
chr4_114681226_114681413	0.57	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	905	0.74
chr6_5996671_5997190	0.57	NRN1	neuritin 1	10270	0.25
chr11_9599012_9599618	0.57	WEE1	WEE1 G2 checkpoint kinase	17	0.78
chr7_30323590_30323942	0.57	ZNRF2	zinc and ring finger 2	157	0.96
chr19_18155761_18156209	0.57	ARRDC2	arrestin domain containing 2	37008	0.1
chr15_61497485_61497898	0.57	RP11-39M21.2		6421	0.23
chr9_125227065_125227303	0.57	RP11-542K23.9		6453	0.13
chr11_67417906_67418392	0.56	ACY3	aspartoacylase (aminocyclase) 3	19	0.96
chr3_195267974_195268163	0.56	PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	2108	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	1.4	GO:0070670	response to interleukin-4(GO:0070670)
0.2	1.0	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.2	0.6	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	0.6	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.2	0.5	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.2	0.5	GO:0032825	regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.2	0.5	GO:0021859	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.2	0.2	GO:0001779	natural killer cell differentiation(GO:0001779)
0.2	0.5	GO:0018242	protein O-linked glycosylation via serine(GO:0018242) protein O-linked glycosylation via threonine(GO:0018243)
0.2	0.8	GO:0042989	sequestering of actin monomers(GO:0042989)
0.2	0.6	GO:0010761	fibroblast migration(GO:0010761)
0.2	0.5	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1	0.4	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.7	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.1	0.4	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1	0.4	GO:0006530	asparagine catabolic process(GO:0006530) asparagine catabolic process via L-aspartate(GO:0033345)
0.1	1.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	1.4	GO:0032727	positive regulation of interferon-alpha production(GO:0032727)
0.1	0.1	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:0070828	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.1	0.6	GO:0030581	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) regulation by virus of viral protein levels in host cell(GO:0046719) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.1	0.4	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	1.1	GO:0032456	endocytic recycling(GO:0032456)
0.1	0.5	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.1	0.3	GO:0006089	lactate metabolic process(GO:0006089)
0.1	0.3	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.1	0.4	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.1	GO:0000255	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.1	0.3	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.1	0.4	GO:0002327	immature B cell differentiation(GO:0002327) pre-B cell differentiation(GO:0002329)
0.1	0.3	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.4	GO:0090190	positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1	0.3	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.1	0.3	GO:0034135	regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.1	0.5	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.1	0.2	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.4	GO:0006172	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.1	0.1	GO:0006925	inflammatory cell apoptotic process(GO:0006925)
0.1	0.2	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.1	0.3	GO:0045007	depurination(GO:0045007)
0.1	0.6	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.1	0.5	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.1	0.2	GO:0032060	bleb assembly(GO:0032060)
0.1	0.5	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.1	0.3	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.2	GO:0032914	positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1	0.3	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.1	0.9	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.1	0.3	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.1	0.3	GO:1903224	endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1	0.4	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	0.3	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.1	0.3	GO:0021508	floor plate formation(GO:0021508)
0.1	0.4	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.1	0.3	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.4	GO:0009120	deoxyribonucleoside metabolic process(GO:0009120)
0.1	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.5	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.4	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.5	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.2	GO:0010716	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.2	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.1	0.3	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.1	0.2	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.1	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1	0.2	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.4	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.1	0.3	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.1	0.4	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.1	0.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.1	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.3	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.1	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.4	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.1	1.2	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1	0.4	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1	0.2	GO:0090266	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.1	0.2	GO:0055064	cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.1	GO:0000212	meiotic spindle organization(GO:0000212)
0.1	0.5	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.3	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.3	GO:0045793	positive regulation of cell size(GO:0045793)
0.1	0.3	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.1	0.3	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.1	0.2	GO:0007144	female meiosis I(GO:0007144)
0.1	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.1	GO:0045341	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1	0.4	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.1	0.7	GO:0031648	protein destabilization(GO:0031648)
0.1	0.2	GO:0002538	arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1	0.2	GO:0002911	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.1	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.1	0.2	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.3	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.1	0.6	GO:0014037	Schwann cell differentiation(GO:0014037)
0.1	0.4	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1	0.2	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.1	GO:0032817	regulation of natural killer cell proliferation(GO:0032817)
0.1	0.4	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	1.0	GO:0006611	protein export from nucleus(GO:0006611)
0.1	0.3	GO:0000729	DNA double-strand break processing(GO:0000729)
0.1	0.2	GO:0071397	cellular response to sterol(GO:0036315) cellular response to cholesterol(GO:0071397)
0.1	0.2	GO:0071636	positive regulation of transforming growth factor beta production(GO:0071636)
0.1	0.2	GO:0010224	response to UV-B(GO:0010224)
0.1	0.1	GO:0002448	mast cell mediated immunity(GO:0002448)
0.1	0.2	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.1	GO:0031646	positive regulation of neurological system process(GO:0031646)
0.1	0.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.1	0.2	GO:0043247	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1	0.1	GO:0021831	embryonic olfactory bulb interneuron precursor migration(GO:0021831)
0.1	0.2	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.1	0.3	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.4	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0010831	positive regulation of myotube differentiation(GO:0010831)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.3	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.8	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.2	GO:0001554	luteolysis(GO:0001554)
0.0	0.1	GO:0051138	NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	1.0	GO:0006309	DNA catabolic process, endonucleolytic(GO:0000737) apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.0	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.2	GO:0002483	antigen processing and presentation of endogenous peptide antigen(GO:0002483) antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0	0.1	GO:0060510	lung saccule development(GO:0060430) Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0001866	NK T cell proliferation(GO:0001866)
0.0	0.2	GO:0032897	negative regulation of viral transcription(GO:0032897)
0.0	0.7	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.2	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.3	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0015917	aminophospholipid transport(GO:0015917)
0.0	0.2	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.2	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.0	0.0	GO:0072540	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.2	GO:0043276	anoikis(GO:0043276)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.5	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.6	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.6	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.6	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.3	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.5	GO:0032608	interferon-beta production(GO:0032608)
0.0	0.1	GO:0072577	endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0	0.1	GO:0072224	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.0	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.1	GO:1901976	regulation of cell cycle checkpoint(GO:1901976)
0.0	0.1	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.2	GO:0009313	oligosaccharide catabolic process(GO:0009313)
0.0	0.1	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
0.0	0.2	GO:0051307	resolution of meiotic recombination intermediates(GO:0000712) meiotic chromosome separation(GO:0051307)
0.0	0.3	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.3	GO:0065005	protein-lipid complex assembly(GO:0065005)
0.0	0.5	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.4	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0046831	regulation of nucleobase-containing compound transport(GO:0032239) regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.0	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.2	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
0.0	0.1	GO:0051608	histamine transport(GO:0051608)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.0	GO:0034698	response to gonadotropin(GO:0034698)
0.0	0.0	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0032212	positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0	0.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.3	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.4	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.1	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0	0.1	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.1	GO:0031297	replication fork processing(GO:0031297)
0.0	0.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.0	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.0	0.2	GO:0052646	phosphatidylserine metabolic process(GO:0006658) alditol phosphate metabolic process(GO:0052646)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.1	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.9	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.2	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0	0.1	GO:0043312	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0	0.1	GO:0010225	response to UV-C(GO:0010225)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0042119	neutrophil activation(GO:0042119)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0090305	nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0	0.2	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.2	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.8	GO:0006885	regulation of pH(GO:0006885)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0003094	regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.0	0.5	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:1901341	activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.7	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.3	GO:1902583	multi-organism transport(GO:0044766) transport of virus(GO:0046794) intracellular transport of virus(GO:0075733) multi-organism localization(GO:1902579) multi-organism intracellular transport(GO:1902583)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.5	GO:0030968	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.0	0.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
0.0	0.0	GO:0009214	cyclic nucleotide catabolic process(GO:0009214)
0.0	0.1	GO:0043173	nucleotide salvage(GO:0043173)
0.0	0.7	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0	0.2	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.2	GO:0034405	response to fluid shear stress(GO:0034405)
0.0	0.9	GO:0016579	protein deubiquitination(GO:0016579)
0.0	0.1	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.0	0.1	GO:0070076	histone lysine demethylation(GO:0070076)
0.0	0.1	GO:0070570	regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.0	0.1	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.2	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.1	GO:0000002	mitochondrial genome maintenance(GO:0000002)
0.0	0.0	GO:0032232	negative regulation of actin filament bundle assembly(GO:0032232)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0	0.1	GO:0030952	establishment or maintenance of cytoskeleton polarity(GO:0030952)
0.0	0.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.6	GO:0008156	negative regulation of DNA replication(GO:0008156)
0.0	0.0	GO:0006356	regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0	0.1	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278) positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.4	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.3	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) negative regulation of lipoprotein particle clearance(GO:0010985)
0.0	0.2	GO:0002474	antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.2	GO:0046415	urate metabolic process(GO:0046415)
0.0	0.0	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0007004	telomere maintenance via telomerase(GO:0007004)
0.0	0.1	GO:0060972	left/right pattern formation(GO:0060972)
0.0	0.8	GO:0051320	S phase(GO:0051320)
0.0	0.2	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.0	GO:0032469	endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0	0.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0045022	early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0	1.8	GO:0006364	rRNA processing(GO:0006364)
0.0	0.1	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.1	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0039694	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0	0.0	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0008595	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0071354	cellular response to interleukin-6(GO:0071354)
0.0	0.1	GO:0072676	lymphocyte chemotaxis(GO:0048247) lymphocyte migration(GO:0072676)
0.0	0.1	GO:1904030	negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.0	GO:1903960	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0042160	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.1	GO:0046337	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.2	GO:1902603	carnitine shuttle(GO:0006853) carnitine transmembrane transport(GO:1902603)
0.0	0.5	GO:0006338	chromatin remodeling(GO:0006338)
0.0	0.2	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0016572	histone phosphorylation(GO:0016572)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.0	GO:0046813	receptor-mediated virion attachment to host cell(GO:0046813)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.2	GO:0035329	hippo signaling(GO:0035329)
0.0	0.6	GO:0006402	mRNA catabolic process(GO:0006402)
0.0	0.2	GO:0046579	positive regulation of Ras protein signal transduction(GO:0046579)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0033146	regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.0	0.2	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.7	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0006552	leucine catabolic process(GO:0006552)
0.0	0.3	GO:0006997	nucleus organization(GO:0006997)
0.0	0.8	GO:0051291	protein heterooligomerization(GO:0051291)
0.0	0.0	GO:0046022	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897) regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.0	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.0	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.2	GO:0000723	telomere maintenance(GO:0000723)
0.0	0.0	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	1.5	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.1	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	1.2	GO:0008033	tRNA processing(GO:0008033)
0.0	0.0	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.3	GO:0043489	RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.0	0.1	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.0	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.3	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.1	GO:0060037	pharyngeal system development(GO:0060037)
0.0	0.0	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.0	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.1	GO:0006312	mitotic recombination(GO:0006312)
0.0	0.1	GO:0050706	regulation of interleukin-1 beta secretion(GO:0050706)
0.0	0.1	GO:2000272	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) negative regulation of receptor activity(GO:2000272)
0.0	0.1	GO:0046457	prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0	0.0	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0010506	regulation of autophagy(GO:0010506)
0.0	0.4	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0060055	angiogenesis involved in wound healing(GO:0060055)
0.0	0.1	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	0.3	GO:0032387	negative regulation of intracellular transport(GO:0032387)
0.0	0.1	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.2	GO:0006349	regulation of gene expression by genetic imprinting(GO:0006349)
0.0	0.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.1	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0000089	mitotic metaphase(GO:0000089)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0045576	mast cell activation(GO:0045576)
0.0	1.3	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0	0.0	GO:0006405	RNA export from nucleus(GO:0006405)
0.0	0.1	GO:0033233	regulation of protein sumoylation(GO:0033233)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0021707	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.0	GO:0002468	dendritic cell antigen processing and presentation(GO:0002468) positive regulation of antigen processing and presentation(GO:0002579) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.6	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.0	0.5	GO:0006986	response to unfolded protein(GO:0006986)
0.0	0.0	GO:0001881	receptor recycling(GO:0001881)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.0	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.0	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.0	GO:0046835	carbohydrate phosphorylation(GO:0046835)
0.0	0.1	GO:0006119	oxidative phosphorylation(GO:0006119)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.1	GO:0032375	negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375)
0.0	0.0	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.0	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0000270	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0006458	'de novo' protein folding(GO:0006458)
0.0	0.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.4	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0015949	nucleobase-containing small molecule interconversion(GO:0015949)
0.0	0.0	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.3	GO:0006071	glycerol metabolic process(GO:0006071)
0.0	0.1	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.2	GO:0050434	positive regulation of viral transcription(GO:0050434)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.4	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.6	GO:0006165	nucleoside diphosphate phosphorylation(GO:0006165)
0.0	0.0	GO:0042637	catagen(GO:0042637)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.0	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.0	GO:0014051	gamma-aminobutyric acid secretion(GO:0014051)
0.0	0.4	GO:0007259	JAK-STAT cascade(GO:0007259) STAT cascade(GO:0097696)
0.0	0.0	GO:0006907	pinocytosis(GO:0006907)
0.0	0.1	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.2	GO:0030514	negative regulation of BMP signaling pathway(GO:0030514)
0.0	0.0	GO:0032733	positive regulation of interleukin-10 production(GO:0032733)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0051654	establishment of mitochondrion localization(GO:0051654)
0.0	0.0	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.0	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	2.7	GO:0008380	RNA splicing(GO:0008380)
0.0	0.1	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.0	GO:0031033	myosin filament organization(GO:0031033)
0.0	0.0	GO:0014050	negative regulation of glutamate secretion(GO:0014050)
0.0	0.0	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.1	GO:0035121	obsolete tail morphogenesis(GO:0035121)
0.0	0.0	GO:0048291	isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.0	GO:0032414	positive regulation of ion transmembrane transporter activity(GO:0032414)
0.0	0.8	GO:0006414	translational elongation(GO:0006414)
0.0	0.1	GO:0050766	positive regulation of phagocytosis(GO:0050766)
0.0	0.4	GO:0051592	response to calcium ion(GO:0051592)
0.0	0.1	GO:0006284	base-excision repair(GO:0006284)
0.0	0.0	GO:0035269	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.0	0.0	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.1	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0006635	fatty acid beta-oxidation(GO:0006635)
0.0	0.0	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.1	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.0	0.0	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.0	0.1	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.0	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.0	GO:0031958	corticosteroid receptor signaling pathway(GO:0031958)
0.0	0.1	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.1	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.0	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:0008088	axo-dendritic transport(GO:0008088)
0.0	0.2	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.0	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:2000171	negative regulation of dendrite development(GO:2000171)
0.0	0.4	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.0	0.2	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.0	0.1	GO:0045806	negative regulation of endocytosis(GO:0045806)
0.0	0.0	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0016236	macroautophagy(GO:0016236)
0.0	0.0	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.0	GO:0035306	positive regulation of dephosphorylation(GO:0035306) positive regulation of protein dephosphorylation(GO:0035307)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	0.5	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	0.6	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.3	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.3	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.1	0.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1	0.7	GO:0002102	podosome(GO:0002102)
0.1	0.5	GO:0042382	paraspeckles(GO:0042382)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.4	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.5	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	0.3	GO:0042583	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.3	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.4	GO:0070761	pre-snoRNP complex(GO:0070761)
0.1	0.3	GO:0042825	TAP complex(GO:0042825)
0.1	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.1	0.7	GO:0071565	nBAF complex(GO:0071565)
0.1	0.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.1	0.4	GO:0001741	XY body(GO:0001741)
0.1	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.1	0.3	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.1	0.2	GO:0030891	VCB complex(GO:0030891)
0.1	0.2	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	0.2	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.3	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.3	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	0.8	GO:0000178	exosome (RNase complex)(GO:0000178)
0.1	0.2	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	0.3	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.1	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.1	0.3	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.1	0.3	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.1	0.6	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.1	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0017059	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	1.0	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.0	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.3	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.8	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.3	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.2	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.5	GO:0045120	pronucleus(GO:0045120)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.5	GO:0030914	STAGA complex(GO:0030914)
0.0	0.2	GO:0042598	obsolete vesicular fraction(GO:0042598)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.8	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	1.2	GO:0042645	mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	1.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	1.5	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.6	GO:0005798	Golgi-associated vesicle(GO:0005798)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0043596	nuclear replication fork(GO:0043596)
0.0	0.1	GO:0000803	sex chromosome(GO:0000803) sex chromatin(GO:0001739)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.3	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.4	GO:0031672	A band(GO:0031672)
0.0	1.7	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.4	GO:0001772	immunological synapse(GO:0001772)
0.0	0.2	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.5	GO:0005844	polysome(GO:0005844)
0.0	0.5	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.4	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	1.5	GO:0034399	nuclear periphery(GO:0034399)
0.0	0.7	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.3	GO:0005849	mRNA cleavage factor complex(GO:0005849)
0.0	0.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	3.4	GO:0005769	early endosome(GO:0005769)
0.0	0.6	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.7	GO:0055037	recycling endosome(GO:0055037)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.7	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.9	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.4	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.7	GO:0030175	filopodium(GO:0030175)
0.0	0.1	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.2	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.0	GO:0032059	bleb(GO:0032059)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	2.0	GO:0031965	nuclear membrane(GO:0031965)
0.0	0.3	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	1.1	GO:0042383	sarcolemma(GO:0042383)
0.0	0.9	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.9	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.4	GO:0030117	membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0	0.1	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.7	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.5	GO:0005884	actin filament(GO:0005884)
0.0	0.3	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.5	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
0.0	0.3	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742) outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.7	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0000346	transcription export complex(GO:0000346)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.2	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.5	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.1	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0001740	X chromosome(GO:0000805) Barr body(GO:0001740)
0.0	0.0	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.7	GO:0000776	kinetochore(GO:0000776)
0.0	0.0	GO:0071778	obsolete WINAC complex(GO:0071778)
0.0	0.7	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	0.0	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.7	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.1	GO:0042101	T cell receptor complex(GO:0042101)
0.0	1.5	GO:0005840	ribosome(GO:0005840)
0.0	0.0	GO:0032279	asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0	0.1	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.0	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.6	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.0	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.2	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.0	GO:0031304	intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.4	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.0	0.6	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0035267	NuA4 histone acetyltransferase complex(GO:0035267)
0.0	0.2	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.1	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.3	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587)
0.0	0.1	GO:0001527	microfibril(GO:0001527)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.1	GO:0005775	vacuolar lumen(GO:0005775)
0.0	0.0	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.3	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	2.1	GO:0005768	endosome(GO:0005768)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.2	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.3	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	0.2	GO:0005905	clathrin-coated pit(GO:0005905)
0.0	0.1	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	1.2	GO:1990904	intracellular ribonucleoprotein complex(GO:0030529) ribonucleoprotein complex(GO:1990904)
0.0	0.0	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0005796	Golgi lumen(GO:0005796)
0.0	8.0	GO:0005730	nucleolus(GO:0005730)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	8.5	GO:0005739	mitochondrion(GO:0005739)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2	0.7	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.2	1.2	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.2	0.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.2	0.6	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.2	0.5	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2	0.5	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.2	0.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.2	0.8	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1	0.7	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.6	GO:0016531	copper chaperone activity(GO:0016531)
0.1	0.5	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.1	0.8	GO:0005521	lamin binding(GO:0005521)
0.1	0.8	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.1	0.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.5	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	1.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.1	0.2	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.6	GO:0032407	MutSalpha complex binding(GO:0032407)
0.1	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.1	0.3	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.5	GO:0030955	potassium ion binding(GO:0030955)
0.1	0.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.2	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.9	GO:0015385	sodium:proton antiporter activity(GO:0015385)
0.1	0.3	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.3	GO:0043515	kinetochore binding(GO:0043515)
0.1	1.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1	0.5	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.3	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.1	0.7	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1	0.6	GO:0008494	translation activator activity(GO:0008494)
0.1	0.2	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.3	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1	0.2	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.2	GO:1990939	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.4	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.7	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	0.8	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.1	0.5	GO:0030507	spectrin binding(GO:0030507)
0.1	0.3	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.1	0.3	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.3	GO:0046978	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1	0.2	GO:0048039	ubiquinone binding(GO:0048039)
0.1	0.4	GO:0008312	7S RNA binding(GO:0008312)
0.1	0.2	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.3	GO:0004064	arylesterase activity(GO:0004064)
0.1	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.3	GO:0019237	centromeric DNA binding(GO:0019237)
0.1	0.3	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.1	0.1	GO:0005113	patched binding(GO:0005113)
0.1	0.5	GO:0003785	actin monomer binding(GO:0003785)
0.1	0.2	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1	1.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.1	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.2	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469)
0.1	0.2	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1	0.2	GO:0050265	RNA uridylyltransferase activity(GO:0050265)
0.1	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.1	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.2	GO:0004111	creatine kinase activity(GO:0004111)
0.1	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	0.7	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.1	0.3	GO:0043422	protein kinase B binding(GO:0043422)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.2	GO:0045569	TRAIL binding(GO:0045569)
0.1	0.2	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.3	GO:0015288	porin activity(GO:0015288)
0.1	0.3	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.1	0.3	GO:0001727	lipid kinase activity(GO:0001727)
0.1	0.2	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1	0.2	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.2	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.0	0.3	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.8	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.3	GO:0031491	nucleosome binding(GO:0031491)
0.0	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.8	GO:0043621	protein self-association(GO:0043621)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.4	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0019211	phosphatase activator activity(GO:0019211)
0.0	0.3	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.3	GO:0042805	actinin binding(GO:0042805)
0.0	2.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.4	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.5	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.3	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.0	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0034593	phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0	0.0	GO:0008186	RNA-dependent ATPase activity(GO:0008186)
0.0	0.5	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175)
0.0	0.3	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.2	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0008518	reduced folate carrier activity(GO:0008518)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.4	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.4	GO:0003906	DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0	0.3	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	1.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.6	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.8	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.3	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.2	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.2	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.9	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.6	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.2	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	1.4	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.3	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0098847	single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.3	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.3	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.3	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.3	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0043176	amine binding(GO:0043176)
0.0	0.4	GO:0043130	ubiquitin binding(GO:0043130)
0.0	0.3	GO:0008408	3'-5' exonuclease activity(GO:0008408)
0.0	0.1	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.2	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	0.4	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.3	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.5	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.3	GO:0004835	tubulin-tyrosine ligase activity(GO:0004835)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	1.9	GO:0070035	ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.3	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.2	GO:0005123	death receptor binding(GO:0005123)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0004675	transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.5	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.3	GO:0016409	palmitoyltransferase activity(GO:0016409)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.0	GO:0032182	ubiquitin-like protein binding(GO:0032182)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.1	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.7	GO:0003954	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.4	GO:0042054	histone methyltransferase activity(GO:0042054)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.2	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0043274	phospholipase binding(GO:0043274)
0.0	3.8	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.2	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.0	GO:0032558	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.0	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0	0.1	GO:0016165	linoleate 13S-lipoxygenase activity(GO:0016165)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.2	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.0	0.4	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.0	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.5	GO:0061733	peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0016997	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.0	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.3	GO:0035250	UDP-galactosyltransferase activity(GO:0035250)
0.0	0.1	GO:0030515	snoRNA binding(GO:0030515)
0.0	1.0	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.1	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.0	0.1	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0031013	troponin I binding(GO:0031013)
0.0	0.1	GO:0070568	guanylyltransferase activity(GO:0070568)
0.0	0.2	GO:0042301	phosphate ion binding(GO:0042301)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0008493	tetracycline transporter activity(GO:0008493)
0.0	2.5	GO:0016874	ligase activity(GO:0016874)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.0	GO:1902936	phosphatidylinositol bisphosphate binding(GO:1902936)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.3	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.3	GO:0003725	double-stranded RNA binding(GO:0003725)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.1	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.0	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.0	0.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.0	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	1.9	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0099604	calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0	0.1	GO:0051019	mitogen-activated protein kinase binding(GO:0051019)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.0	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0019956	chemokine binding(GO:0019956)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.5	GO:0004221	obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0	0.1	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.0	0.0	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	1.2	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.3	GO:0002020	protease binding(GO:0002020)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.3	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.0	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.6	GO:0047485	protein N-terminus binding(GO:0047485)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.0	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.0	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.0	0.0	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.0	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	3.7	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.0	0.0	GO:0031708	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	1.7	GO:0016564	obsolete transcription repressor activity(GO:0016564)
0.0	0.2	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.0	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:1901981	phosphatidylinositol phosphate binding(GO:1901981)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.5	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.2	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.0	GO:0008170	N-methyltransferase activity(GO:0008170)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
0.0	0.0	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.1	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.2	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	0.6	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.7	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	1.0	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	0.4	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	0.6	PID ALK2 PATHWAY	ALK2 signaling events
0.1	0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	0.8	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	1.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.0	2.2	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.0	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.8	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.0	1.2	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.0	1.6	PID P53 REGULATION PATHWAY	p53 pathway
0.0	1.3	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.8	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.7	PID ATM PATHWAY	ATM pathway
0.0	0.5	PID IGF1 PATHWAY	IGF1 pathway
0.0	1.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.2	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.3	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.1	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.2	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	1.2	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.4	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.1	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.3	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.0	PID EPO PATHWAY	EPO signaling pathway
0.0	0.0	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	0.7	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.1	PID ATR PATHWAY	ATR signaling pathway
0.0	0.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.1	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.1	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.4	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.0	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.0	0.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1	0.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	1.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.2	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.1	0.3	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1	0.8	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1	0.5	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	0.8	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	0.4	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.1	0.1	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.1	0.6	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	0.8	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	0.7	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	1.6	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.4	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.8	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	1.2	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.6	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.6	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	2.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.4	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.0	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.0	0.8	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.8	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.4	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.7	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.3	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.7	REACTOME PROTEIN FOLDING	Genes involved in Protein folding
0.0	0.6	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.1	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	1.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.5	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.2	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.0	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.3	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	2.2	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.0	0.2	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	1.0	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.5	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.0	REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S	Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.3	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	0.0	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.5	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	1.3	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.3	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.4	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.3	REACTOME TRNA AMINOACYLATION	Genes involved in tRNA Aminoacylation
0.0	0.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.0	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.4	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS	Genes involved in TGF-beta receptor signaling activates SMADs
0.0	0.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.0	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.0	REACTOME PI3K AKT ACTIVATION	Genes involved in PI3K/AKT activation
0.0	0.1	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.3	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.0	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.0	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.4	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.1	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	1.2	REACTOME METABOLISM OF PROTEINS	Genes involved in Metabolism of proteins
0.0	0.3	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors

Results for IRF6_IRF4_IRF5

Z-value: 3.40

Motif logo

Transcription factors associated with IRF6_IRF4_IRF5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IRF6_IRF4_IRF5 motif across conditions

Conditions sorted by the z-value of the IRF6_IRF4_IRF5 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF6_IRF4_IRF5

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: