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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for IRF7

Z-value: 4.12

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Transcription factors associated with IRF7

Gene Symbol	Gene ID	Gene Info
IRF7 Ensembl NCBI GeneCards UniProt	ENSG00000185507.15	interferon regulatory factor 7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_616811_616962	IRF7	887	0.351824	-0.78	1.3e-02	Click!
chr11_617096_617247	IRF7	1172	0.258905	-0.71	3.2e-02	Click!
chr11_614388_614539	IRF7	1163	0.261680	-0.53	1.5e-01	Click!
chr11_615153_615351	IRF7	374	0.704035	-0.52	1.5e-01	Click!
chr11_613046_613197	IRF7	2505	0.124591	-0.46	2.1e-01	Click!

Activity of the IRF7 motif across conditions

Conditions sorted by the z-value of the IRF7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_47735595_47736220	2.48	BBC3	BCL2 binding component 3	116	0.95
chr8_42063953_42065062	1.66	PLAT	plasminogen activator, tissue	576	0.71
chr5_92918344_92919004	1.41	NR2F1	nuclear receptor subfamily 2, group F, member 1	369	0.84
chr18_40710046_40710304	1.34	RIT2	Ras-like without CAAX 2	14518	0.31
chr1_59528139_59528464	1.34	FGGY	FGGY carbohydrate kinase domain containing	234009	0.02
chr3_189767153_189767327	1.33	ENSG00000265045	.	64483	0.1
chr2_230035862_230036013	1.30	PID1	phosphotyrosine interaction domain containing 1	60864	0.14
chr11_116064544_116064938	1.28	ENSG00000238625	.	126320	0.06
chrX_34673939_34674563	1.27	TMEM47	transmembrane protein 47	1154	0.68
chr3_100711576_100712203	1.27	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr2_212942952_212943169	1.26	ENSG00000221782	.	348024	0.01
chr8_69905056_69905287	1.22	ENSG00000238808	.	117638	0.07
chr7_78398482_78399243	1.18	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1534	0.56
chr19_13137194_13137536	1.16	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1554	0.23
chr6_112210280_112210648	1.15	FYN	FYN oncogene related to SRC, FGR, YES	15809	0.27
chr11_94829276_94829597	1.15	ENDOD1	endonuclease domain containing 1	6462	0.24
chr17_78044749_78045392	1.15	CCDC40	coiled-coil domain containing 40	12346	0.15
chr3_114477625_114477831	1.15	ZBTB20	zinc finger and BTB domain containing 20	59	0.98
chr20_10720180_10720390	1.14	JAG1	jagged 1	65591	0.13
chr1_57042434_57042715	1.11	PPAP2B	phosphatidic acid phosphatase type 2B	2667	0.39
chr6_169653425_169653684	1.09	THBS2	thrombospondin 2	585	0.83
chr7_94025115_94025296	1.08	COL1A2	collagen, type I, alpha 2	1332	0.57
chr17_12568379_12568897	1.07	MYOCD	myocardin	668	0.75
chr3_86894495_86894646	1.07	VGLL3	vestigial like 3 (Drosophila)	145282	0.05
chr8_29028850_29029034	1.07	ENSG00000264328	.	28732	0.15
chr6_94494975_94495370	1.06	ENSG00000252249	.	93652	0.1
chr12_3994355_3994594	1.06	PARP11	poly (ADP-ribose) polymerase family, member 11	11866	0.23
chr6_166259879_166260251	1.05	SDIM1	stress responsive DNAJB4 interacting membrane protein 1	49660	0.16
chr10_734164_734382	1.04	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	1333	0.42
chrX_44491318_44491661	1.02	ENSG00000252120	.	54805	0.15
chrX_99900030_99900181	1.01	SRPX2	sushi-repeat containing protein, X-linked 2	890	0.57
chr5_74344353_74344573	1.01	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	17739	0.26
chr6_39498249_39498478	1.01	KIF6	kinesin family member 6	65673	0.13
chr19_49661333_49661989	1.01	TRPM4	transient receptor potential cation channel, subfamily M, member 4	562	0.58
chr4_113831338_113831756	1.00	RP11-119H12.6		28061	0.21
chr3_29365630_29365959	0.99	RBMS3-AS3	RBMS3 antisense RNA 3	33577	0.18
chr11_85962410_85962578	0.98	EED	embryonic ectoderm development	6218	0.24
chr9_109876837_109877058	0.98	RP11-508N12.2		11678	0.29
chr5_95768411_95768678	0.97	PCSK1	proprotein convertase subtilisin/kexin type 1	440	0.89
chr2_180726238_180726902	0.97	ZNF385B	zinc finger protein 385B	338	0.8
chr1_170169826_170170116	0.97	ENSG00000263390	.	49452	0.14
chr11_2966476_2966712	0.96	PHLDA2	pleckstrin homology-like domain, family A, member 2	15909	0.11
chr3_185960084_185960372	0.96	DGKG	diacylglycerol kinase, gamma 90kDa	38275	0.19
chr11_61367220_61367407	0.95	SYT7	synaptotagmin VII	18693	0.17
chr6_151392247_151392482	0.95	RP1-292B18.3		15171	0.18
chr1_11028380_11028591	0.94	C1orf127	chromosome 1 open reading frame 127	4227	0.17
chr13_37492943_37493377	0.93	SMAD9	SMAD family member 9	1215	0.52
chr12_76422565_76423423	0.93	RP11-290L1.3		1280	0.41
chr8_93113958_93114847	0.93	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	1052	0.69
chr2_201021102_201021310	0.92	SPATS2L	spermatogenesis associated, serine-rich 2-like	149398	0.04
chr7_54972295_54972520	0.92	ENSG00000252054	.	38896	0.2
chr10_118425052_118425217	0.91	C10orf82	chromosome 10 open reading frame 82	4332	0.18
chr8_59777244_59777667	0.91	ENSG00000201231	.	50344	0.17
chr4_4494063_4494282	0.91	STX18-IT1	STX18 intronic transcript 1 (non-protein coding)	10745	0.21
chr3_114582845_114583026	0.91	ZBTB20	zinc finger and BTB domain containing 20	104817	0.08
chr16_14050687_14051311	0.90	CTD-2135D7.2		21507	0.22
chr1_174383473_174383626	0.90	GPR52	G protein-coupled receptor 52	33663	0.21
chr2_190042728_190042905	0.89	COL5A2	collagen, type V, alpha 2	1789	0.42
chr6_6005898_6006049	0.89	NRN1	neuritin 1	1227	0.56
chr6_15654848_15654999	0.89	DTNBP1	dystrobrevin binding protein 1	8283	0.32
chr1_243518007_243518236	0.88	ENSG00000265201	.	8643	0.26
chr17_80339190_80339423	0.88	UTS2R	urotensin 2 receptor	7153	0.1
chr1_70406485_70406636	0.87	ENSG00000240692	.	61285	0.14
chr3_75437644_75437843	0.87	ENSG00000266685	.	19246	0.2
chr4_25939842_25939995	0.87	SMIM20	small integral membrane protein 20	23987	0.24
chr2_205427282_205427476	0.86	PARD3B	par-3 family cell polarity regulator beta	16656	0.31
chr3_114170562_114171054	0.85	ZBTB20	zinc finger and BTB domain containing 20	2722	0.36
chr3_61550061_61550235	0.85	PTPRG	protein tyrosine phosphatase, receptor type, G	2563	0.44
chr15_49719079_49719362	0.85	FGF7	fibroblast growth factor 7	3763	0.28
chr5_21818159_21818310	0.84	ENSG00000221615	.	83914	0.11
chr4_95447138_95447322	0.84	PDLIM5	PDZ and LIM domain 5	2354	0.46
chr6_99212409_99212624	0.84	POU3F2	POU class 3 homeobox 2	70064	0.14
chr22_46473276_46473626	0.83	FLJ27365	hsa-mir-4763	2741	0.14
chr5_89784629_89784780	0.83	POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	13992	0.17
chr3_39475311_39475597	0.83	ENSG00000264724	.	16483	0.13
chr5_96880232_96880460	0.83	CTD-2215E18.2		342762	0.01
chr9_4111551_4111753	0.82	GLIS3	GLIS family zinc finger 3	33541	0.19
chr9_133656128_133656348	0.82	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	54215	0.13
chr1_103571993_103572213	0.82	COL11A1	collagen, type XI, alpha 1	1631	0.56
chr9_36039449_36039608	0.81	RECK	reversion-inducing-cysteine-rich protein with kazal motifs	3098	0.27
chr7_16991270_16991421	0.81	AGR3	anterior gradient 3	69734	0.12
chr5_9284375_9284526	0.81	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	18793	0.26
chr11_122072907_122073271	0.81	ENSG00000207994	.	50073	0.12
chr6_81974819_81975050	0.80	RP1-300G12.2		269696	0.02
chr3_93691964_93692115	0.80	PROS1	protein S (alpha)	444	0.76
chr11_121971575_121971803	0.80	RP11-166D19.1		48	0.95
chr18_20138846_20139132	0.80	ENSG00000206827	.	88556	0.09
chr2_190041307_190041749	0.80	COL5A2	collagen, type V, alpha 2	3077	0.31
chr4_114899856_114900283	0.80	ARSJ	arylsulfatase family, member J	83	0.98
chr12_75783464_75783615	0.80	CAPS2	calcyphosine 2	1142	0.37
chr3_59101698_59102091	0.80	C3orf67	chromosome 3 open reading frame 67	66084	0.15
chr6_148846386_148846777	0.79	ENSG00000223322	.	1205	0.64
chr15_49718551_49718707	0.79	FGF7	fibroblast growth factor 7	3172	0.3
chr21_29827859_29828029	0.79	ENSG00000251894	.	287586	0.01
chr3_23804583_23804865	0.79	ENSG00000238672	.	4378	0.25
chr1_235795999_235796340	0.79	GNG4	guanine nucleotide binding protein (G protein), gamma 4	17124	0.25
chr2_197457255_197457512	0.78	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	48	0.98
chr8_90961766_90961973	0.78	NBN	nibrin	32014	0.16
chr12_81472109_81472459	0.78	ACSS3	acyl-CoA synthetase short-chain family member 3	448	0.87
chr4_15471787_15471987	0.78	CC2D2A	coiled-coil and C2 domain containing 2A	250	0.93
chr4_160170135_160170337	0.78	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	17797	0.23
chr19_15362877_15363312	0.78	EPHX3	epoxide hydrolase 3	18848	0.15
chr5_60602557_60602745	0.78	ZSWIM6	zinc finger, SWIM-type containing 6	25449	0.25
chr2_227590884_227591406	0.77	ENSG00000263363	.	67636	0.11
chr16_73178105_73178293	0.77	C16orf47	chromosome 16 open reading frame 47	147	0.98
chr2_153263599_153263890	0.77	FMNL2	formin-like 2	71993	0.12
chr4_81153527_81153798	0.76	FGF5	fibroblast growth factor 5	34091	0.16
chr17_49125493_49125644	0.76	SPAG9	sperm associated antigen 9	1329	0.42
chr4_187406737_187407177	0.76	F11-AS1	F11 antisense RNA 1	15194	0.19
chr1_46528401_46528552	0.76	RP4-533D7.4		15986	0.19
chr10_77157105_77157688	0.76	ENSG00000237149	.	3881	0.22
chr7_22767460_22767652	0.76	AC073072.5		317	0.74
chr4_178040847_178041026	0.76	ENSG00000222859	.	61660	0.14
chr22_43685292_43685751	0.76	Z99756.1		13560	0.18
chr8_13363129_13363280	0.75	DLC1	deleted in liver cancer 1	6454	0.24
chr2_163099011_163099583	0.75	FAP	fibroblast activation protein, alpha	261	0.94
chr2_157177264_157177572	0.75	NR4A2	nuclear receptor subfamily 4, group A, member 2	9215	0.28
chr14_52707563_52708006	0.75	PTGDR	prostaglandin D2 receptor (DP)	26647	0.22
chr18_8623491_8623721	0.75	RP11-661O13.1		12739	0.19
chr10_26846763_26846969	0.75	ENSG00000199733	.	48348	0.17
chr1_243400243_243400394	0.74	AC092782.1	Uncharacterized protein	12260	0.17
chr17_46681812_46682018	0.74	HOXB6	homeobox B6	419	0.6
chr11_131416298_131416516	0.74	AP003025.2		5646	0.24
chr14_73358828_73359023	0.74	DPF3	D4, zinc and double PHD fingers, family 3	1871	0.32
chr18_11175685_11175836	0.74	PIEZO2	piezo-type mechanosensitive ion channel component 2	27173	0.27
chr6_46458824_46459774	0.74	RCAN2	regulator of calcineurin 2	200	0.78
chr2_183755742_183755893	0.74	ENSG00000207178	.	17248	0.19
chr5_15620950_15621349	0.74	FBXL7	F-box and leucine-rich repeat protein 7	5058	0.28
chr19_11275038_11275287	0.74	SPC24	SPC24, NDC80 kinetochore complex component	8678	0.12
chr7_94284210_94284966	0.73	SGCE	sarcoglycan, epsilon	822	0.48
chr9_80437599_80437890	0.73	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	171	0.98
chr2_198703252_198703452	0.73	PLCL1	phospholipase C-like 1	28370	0.2
chr4_111397420_111397787	0.73	ENPEP	glutamyl aminopeptidase (aminopeptidase A)	374	0.89
chr3_112355873_112356097	0.73	CCDC80	coiled-coil domain containing 80	959	0.65
chr1_54197803_54198068	0.73	GLIS1	GLIS family zinc finger 1	1942	0.34
chr12_88809886_88810316	0.73	ENSG00000199245	.	14118	0.29
chr1_172109224_172109375	0.73	ENSG00000207949	.	1252	0.44
chr2_223916565_223916791	0.73	KCNE4	potassium voltage-gated channel, Isk-related family, member 4	146	0.98
chr1_161932087_161932899	0.73	OLFML2B	olfactomedin-like 2B	22529	0.22
chr4_129759576_129759727	0.72	JADE1	jade family PHD finger 1	7063	0.31
chr15_62862079_62862274	0.72	TLN2	talin 2	8612	0.27
chr10_102759781_102760726	0.72	LZTS2	leucine zipper, putative tumor suppressor 2	643	0.52
chr2_8055570_8055940	0.72	ENSG00000221255	.	338783	0.01
chr18_53068422_53068903	0.72	TCF4	transcription factor 4	96	0.98
chr10_95240533_95240684	0.72	MYOF	myoferlin	1343	0.43
chr20_19956969_19957196	0.72	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	40678	0.16
chr3_59101471_59101696	0.72	C3orf67	chromosome 3 open reading frame 67	65773	0.15
chr21_17790454_17790609	0.72	ENSG00000207638	.	120878	0.06
chr8_17555063_17555276	0.72	MTUS1	microtubule associated tumor suppressor 1	10	0.97
chr8_38642475_38642642	0.72	TACC1	transforming, acidic coiled-coil containing protein 1	634	0.71
chr22_50783104_50783895	0.71	PPP6R2	protein phosphatase 6, regulatory subunit 2	1739	0.21
chr3_8545406_8545557	0.71	LMCD1	LIM and cysteine-rich domains 1	1909	0.32
chr12_68221350_68221955	0.71	RP11-335O4.3		156953	0.04
chr13_103478539_103479046	0.71	ENSG00000222301	.	6449	0.13
chr6_26743586_26743955	0.71	ZNF322	zinc finger protein 322	83790	0.08
chr3_112358958_112359194	0.71	CCDC80	coiled-coil domain containing 80	1040	0.62
chr2_43495897_43496225	0.71	AC010883.5		39349	0.17
chr3_114790362_114790748	0.70	ZBTB20	zinc finger and BTB domain containing 20	333	0.94
chr2_63893254_63893651	0.70	ENSG00000221085	.	29217	0.21
chr5_6722325_6722630	0.70	PAPD7	PAP associated domain containing 7	7732	0.28
chr4_126311427_126311944	0.70	FAT4	FAT atypical cadherin 4	3406	0.33
chr22_18507487_18507815	0.70	MICAL3	microtubule associated monooxygenase, calponin and LIM domain containing 3	326	0.86
chr7_16025680_16025831	0.70	ISPD-AS1	ISPD antisense RNA 1	224358	0.02
chr2_145262757_145262908	0.70	ZEB2	zinc finger E-box binding homeobox 2	12283	0.24
chr12_59313144_59313381	0.69	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	65	0.96
chr10_52984247_52984441	0.69	RP11-40C11.2		21222	0.19
chr15_38547811_38548278	0.69	SPRED1	sprouty-related, EVH1 domain containing 1	2662	0.42
chr1_146976513_146976893	0.69	BCL9	B-cell CLL/lymphoma 9	36479	0.19
chr4_15376364_15376854	0.69	C1QTNF7	C1q and tumor necrosis factor related protein 7	434	0.86
chr6_39614678_39614962	0.69	KIF6	kinesin family member 6	7361	0.26
chr20_5840066_5840362	0.69	ENSG00000202380	.	30487	0.16
chr3_37363190_37363371	0.68	ENSG00000222208	.	19860	0.18
chr2_64633040_64633281	0.68	AC008074.3		47772	0.13
chr5_159292374_159292544	0.68	ADRA1B	adrenoceptor alpha 1B	51331	0.16
chr8_93068674_93068825	0.68	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	6442	0.32
chr4_4862278_4863048	0.68	MSX1	msh homeobox 1	1270	0.58
chr2_188353955_188354194	0.67	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	24294	0.21
chr14_65623358_65623814	0.67	ENSG00000222985	.	32326	0.16
chr7_15724850_15725001	0.67	MEOX2	mesenchyme homeobox 2	1512	0.49
chr9_2838300_2838770	0.67	KIAA0020	KIAA0020	5706	0.3
chr15_62916920_62917378	0.67	RP11-625H11.1	Uncharacterized protein	20231	0.19
chr1_65005729_65006114	0.67	ENSG00000264470	.	39609	0.19
chr5_120534956_120535178	0.67	ENSG00000222609	.	488532	0.01
chr2_177000583_177000734	0.67	HOXD3	homeobox D3	1027	0.23
chr6_152701576_152701930	0.67	SYNE1-AS1	SYNE1 antisense RNA 1	72	0.97
chr2_12186341_12186492	0.67	ENSG00000238503	.	15918	0.27
chr2_210390985_210391683	0.67	MAP2	microtubule-associated protein 2	52705	0.18
chr6_15654665_15654816	0.67	DTNBP1	dystrobrevin binding protein 1	8466	0.32
chr8_24366535_24366686	0.67	RP11-561E1.1		5491	0.24
chr7_78400457_78400662	0.67	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	79	0.99
chr8_70379474_70379659	0.67	SULF1	sulfatase 1	344	0.94
chr14_101293745_101294069	0.67	AL117190.2		1630	0.12
chr16_64450292_64450444	0.66	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	643213	0.0
chr10_30138566_30138997	0.66	SVIL	supervillin	114048	0.06
chr3_64674138_64674393	0.66	ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	589	0.78
chr5_9544374_9544669	0.66	SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	1666	0.36
chr1_157980874_157981318	0.66	KIRREL-IT1	KIRREL intronic transcript 1 (non-protein coding)	14244	0.2
chr18_52920366_52920517	0.66	TCF4	transcription factor 4	22461	0.26
chr1_161992740_161992891	0.66	OLFML2B	olfactomedin-like 2B	615	0.79
chr5_139560716_139560896	0.66	CYSTM1	cysteine-rich transmembrane module containing 1	6579	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.5	1.6	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.5	2.0	GO:0070208	protein heterotrimerization(GO:0070208)
0.5	2.9	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.5	1.4	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.4	1.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4	1.7	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.4	1.7	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.4	1.3	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.4	1.4	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.3	1.0	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.3	1.6	GO:1903672	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.3	0.6	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.3	0.9	GO:0048149	behavioral response to ethanol(GO:0048149)
0.3	2.1	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.3	0.6	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.3	0.9	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3	0.8	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.3	0.8	GO:0060596	mammary placode formation(GO:0060596)
0.3	0.8	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.3	1.1	GO:0001757	somite specification(GO:0001757)
0.3	0.8	GO:0060676	ureteric bud formation(GO:0060676)
0.3	0.5	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.2	0.7	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
0.2	1.4	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.2	0.9	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.2	0.9	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	1.7	GO:0060216	definitive hemopoiesis(GO:0060216)
0.2	2.6	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.2	0.7	GO:0033087	negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2	0.9	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	0.5	GO:0048368	lateral mesoderm development(GO:0048368)
0.2	1.6	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.2	0.7	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.2	1.1	GO:0014850	response to muscle activity(GO:0014850)
0.2	5.2	GO:0030199	collagen fibril organization(GO:0030199)
0.2	0.7	GO:0008354	germ cell migration(GO:0008354)
0.2	0.9	GO:0008218	bioluminescence(GO:0008218)
0.2	0.4	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.2	0.4	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.2	0.2	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	1.0	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.2	0.6	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.2	0.8	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.2	0.4	GO:0060363	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.2	0.7	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.2	0.7	GO:0070141	response to UV-A(GO:0070141)
0.2	2.2	GO:0042474	middle ear morphogenesis(GO:0042474)
0.2	0.2	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	1.3	GO:0016540	protein autoprocessing(GO:0016540)
0.2	0.5	GO:0002407	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.2	0.2	GO:0060435	bronchiole development(GO:0060435)
0.2	0.4	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.2	0.5	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.2	0.2	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.2	0.5	GO:0060242	contact inhibition(GO:0060242)
0.2	2.5	GO:0030325	adrenal gland development(GO:0030325)
0.2	0.3	GO:0031223	auditory behavior(GO:0031223)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	0.3	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.2	0.5	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.2	0.3	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	0.7	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.2	0.5	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.2	0.5	GO:0032455	nerve growth factor processing(GO:0032455)
0.2	0.6	GO:0010107	potassium ion import(GO:0010107)
0.2	0.2	GO:1902803	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.2	0.6	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.2	0.5	GO:0001880	Mullerian duct regression(GO:0001880)
0.2	0.6	GO:0070091	glucagon secretion(GO:0070091)
0.2	0.5	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.2	0.8	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	1.7	GO:0043113	receptor clustering(GO:0043113)
0.2	0.3	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.4	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.1	0.3	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.6	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.1	1.3	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.6	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	0.4	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.1	0.6	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.4	GO:0090196	chemokine secretion(GO:0090195) regulation of chemokine secretion(GO:0090196) positive regulation of chemokine secretion(GO:0090197)
0.1	0.8	GO:0046485	ether lipid metabolic process(GO:0046485)
0.1	0.4	GO:0032906	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.5	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.1	0.3	GO:2000178	negative regulation of neuroblast proliferation(GO:0007406) negative regulation of neural precursor cell proliferation(GO:2000178)
0.1	0.3	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.1	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1	0.1	GO:0090103	cochlea morphogenesis(GO:0090103)
0.1	0.4	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.9	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1	0.4	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.6	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.1	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.1	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.2	GO:0042640	anagen(GO:0042640)
0.1	0.6	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.1	0.7	GO:1902692	regulation of neuroblast proliferation(GO:1902692)
0.1	0.3	GO:0050932	regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.1	0.3	GO:0010662	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.3	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.1	0.6	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.1	0.2	GO:0060539	diaphragm development(GO:0060539)
0.1	0.2	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.2	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.1	0.8	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.1	0.4	GO:0032825	natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.1	0.2	GO:0022605	oogenesis stage(GO:0022605)
0.1	0.4	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.1	GO:0035844	cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1	0.4	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0001553	luteinization(GO:0001553)
0.1	0.7	GO:0015871	choline transport(GO:0015871)
0.1	0.2	GO:0009221	pyrimidine deoxyribonucleotide biosynthetic process(GO:0009221)
0.1	0.6	GO:0031000	response to caffeine(GO:0031000)
0.1	0.2	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.2	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.1	0.8	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.1	0.6	GO:0051043	regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.1	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.1	5.9	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1	1.4	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.4	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.3	GO:0034201	response to oleic acid(GO:0034201)
0.1	0.5	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.4	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367)
0.1	0.2	GO:0042635	positive regulation of hair cycle(GO:0042635) regulation of hair follicle development(GO:0051797) positive regulation of hair follicle development(GO:0051798)
0.1	0.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.5	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.3	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.2	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	1.0	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.1	GO:0014041	regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1	0.1	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.1	0.6	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1	0.3	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1	1.9	GO:0051101	regulation of DNA binding(GO:0051101)
0.1	0.4	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1	0.3	GO:0048840	otolith development(GO:0048840)
0.1	0.5	GO:0031641	regulation of myelination(GO:0031641)
0.1	0.4	GO:0030857	negative regulation of epithelial cell differentiation(GO:0030857)
0.1	0.2	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1	0.7	GO:0015074	DNA integration(GO:0015074)
0.1	0.1	GO:0042634	regulation of hair cycle(GO:0042634) cellular response to X-ray(GO:0071481)
0.1	0.4	GO:0032099	negative regulation of appetite(GO:0032099)
0.1	0.3	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.5	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.2	GO:0050955	thermoception(GO:0050955)
0.1	0.4	GO:0043616	keratinocyte proliferation(GO:0043616)
0.1	0.9	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0002686	negative regulation of leukocyte migration(GO:0002686)
0.1	0.6	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.1	0.1	GO:0048532	anatomical structure arrangement(GO:0048532)
0.1	0.2	GO:0014002	astrocyte development(GO:0014002)
0.1	0.2	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.5	GO:0006477	protein sulfation(GO:0006477)
0.1	0.4	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.1	0.2	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1	0.2	GO:0002360	T cell lineage commitment(GO:0002360)
0.1	1.2	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.2	GO:0060073	urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.5	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1	0.4	GO:0046520	sphingoid biosynthetic process(GO:0046520)
0.1	1.4	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.1	0.2	GO:0015670	carbon dioxide transport(GO:0015670)
0.1	0.5	GO:0046716	muscle cell cellular homeostasis(GO:0046716)
0.1	0.4	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1	0.2	GO:0048715	negative regulation of oligodendrocyte differentiation(GO:0048715)
0.1	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.3	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.6	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1	0.3	GO:0048240	sperm capacitation(GO:0048240)
0.1	0.4	GO:0048268	clathrin coat assembly(GO:0048268)
0.1	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.2	GO:0017121	phospholipid scrambling(GO:0017121)
0.1	0.2	GO:0046185	aldehyde catabolic process(GO:0046185)
0.1	0.2	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.3	GO:0021546	rhombomere development(GO:0021546)
0.1	0.2	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.1	0.3	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1	0.3	GO:0031076	embryonic camera-type eye development(GO:0031076)
0.1	0.2	GO:0010719	negative regulation of epithelial to mesenchymal transition(GO:0010719) negative regulation of stem cell differentiation(GO:2000737)
0.1	0.1	GO:0044851	hair cycle phase(GO:0044851) hair follicle maturation(GO:0048820)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.3	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.1	0.3	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	0.4	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	0.3	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1	0.1	GO:2000846	corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1	0.2	GO:0019605	butyrate metabolic process(GO:0019605)
0.1	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.1	0.3	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.4	GO:0001660	fever generation(GO:0001660)
0.1	0.3	GO:0007567	parturition(GO:0007567)
0.1	0.6	GO:0006949	syncytium formation(GO:0006949)
0.1	0.2	GO:0006573	valine metabolic process(GO:0006573)
0.1	0.8	GO:0042730	fibrinolysis(GO:0042730)
0.1	0.4	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.1	0.3	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.1	0.2	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.4	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.1	0.1	GO:0071462	cellular response to water stimulus(GO:0071462)
0.1	0.4	GO:0007616	long-term memory(GO:0007616)
0.1	0.2	GO:0021794	thalamus development(GO:0021794)
0.1	0.5	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.1	0.2	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.1	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.1	0.1	GO:0009414	response to water deprivation(GO:0009414) response to water(GO:0009415)
0.1	0.3	GO:0042523	positive regulation of tyrosine phosphorylation of Stat5 protein(GO:0042523)
0.1	0.1	GO:0090102	cochlea development(GO:0090102)
0.1	0.3	GO:0090280	positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) positive regulation of calcium ion import(GO:0090280)
0.1	0.1	GO:0060433	bronchus development(GO:0060433)
0.1	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	0.6	GO:0014032	neural crest cell development(GO:0014032)
0.1	0.2	GO:0030238	male sex determination(GO:0030238)
0.1	0.9	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.3	GO:0002675	positive regulation of acute inflammatory response(GO:0002675)
0.1	0.3	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.1	0.3	GO:0003156	regulation of organ formation(GO:0003156)
0.1	0.3	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.1	GO:0042320	regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1	0.6	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.1	0.1	GO:0042363	vitamin catabolic process(GO:0009111) fat-soluble vitamin catabolic process(GO:0042363) vitamin D receptor signaling pathway(GO:0070561)
0.1	0.2	GO:0051788	response to misfolded protein(GO:0051788)
0.1	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.1	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0090026	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.0	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.1	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.2	GO:0001508	action potential(GO:0001508)
0.0	0.0	GO:0072678	T cell migration(GO:0072678)
0.0	0.0	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0	0.2	GO:0021983	pituitary gland development(GO:0021983)
0.0	0.2	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.0	0.5	GO:0008210	estrogen metabolic process(GO:0008210)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.3	GO:0071456	cellular response to decreased oxygen levels(GO:0036294) cellular response to oxygen levels(GO:0071453) cellular response to hypoxia(GO:0071456)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.2	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.3	GO:0071450	removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0	1.9	GO:0071772	BMP signaling pathway(GO:0030509) response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0	0.2	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	5.5	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	1.4	GO:0001764	neuron migration(GO:0001764)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.0	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.1	GO:0032730	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.0	GO:0052251	induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.2	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.0	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.4	GO:0071514	genetic imprinting(GO:0071514)
0.0	0.6	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.3	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.6	GO:0042462	eye photoreceptor cell development(GO:0042462)
0.0	0.3	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.3	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.2	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.2	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0060206	estrous cycle phase(GO:0060206)
0.0	0.1	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.3	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0010874	regulation of cholesterol efflux(GO:0010874)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.1	GO:0032098	regulation of appetite(GO:0032098)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.1	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0045822	negative regulation of heart contraction(GO:0045822)
0.0	0.1	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.0	GO:0033033	negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0	0.1	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.0	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.0	0.0	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.9	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:1903427	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of reactive oxygen species biosynthetic process(GO:1903427) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0	0.1	GO:0007530	sex determination(GO:0007530)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.0	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.1	GO:0033240	positive regulation of cellular amine metabolic process(GO:0033240)
0.0	0.1	GO:0030573	bile acid catabolic process(GO:0030573)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.2	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0032096	negative regulation of response to food(GO:0032096)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0016246	RNA interference(GO:0016246)
0.0	0.2	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.1	GO:0050432	catecholamine secretion(GO:0050432)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.0	GO:0055015	ventricular cardiac muscle cell development(GO:0055015)
0.0	0.4	GO:0019933	cAMP-mediated signaling(GO:0019933)
0.0	0.1	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	0.0	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response(GO:0061081)
0.0	0.0	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.0	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.2	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0045066	regulatory T cell differentiation(GO:0045066)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.0	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.0	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.3	GO:0098876	Golgi to plasma membrane transport(GO:0006893) vesicle-mediated transport to the plasma membrane(GO:0098876)
0.0	0.2	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0045830	positive regulation of isotype switching(GO:0045830)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.2	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0051956	negative regulation of amino acid transport(GO:0051956)
0.0	0.6	GO:0010001	glial cell differentiation(GO:0010001)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0060259	regulation of feeding behavior(GO:0060259)
0.0	0.1	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.0	GO:0060291	long-term synaptic potentiation(GO:0060291)
0.0	0.1	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.0	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.1	GO:0044705	mating behavior(GO:0007617) reproductive behavior(GO:0019098) multi-organism reproductive behavior(GO:0044705)
0.0	0.0	GO:0055094	response to lipoprotein particle(GO:0055094)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0060914	heart formation(GO:0060914)
0.0	0.1	GO:0032376	positive regulation of sterol transport(GO:0032373) positive regulation of cholesterol transport(GO:0032376)
0.0	0.2	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.0	GO:0044266	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.0	0.1	GO:0007341	penetration of zona pellucida(GO:0007341)
0.0	0.1	GO:0051930	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.5	GO:0008206	bile acid metabolic process(GO:0008206)
0.0	0.2	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.0	GO:0001878	response to yeast(GO:0001878)
0.0	0.1	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0016556	mRNA modification(GO:0016556)
0.0	0.0	GO:0032610	interleukin-1 alpha production(GO:0032610) interleukin-1 alpha secretion(GO:0050703)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.2	GO:0007631	feeding behavior(GO:0007631)
0.0	0.1	GO:0007416	synapse assembly(GO:0007416)
0.0	0.1	GO:0031427	response to methotrexate(GO:0031427)
0.0	0.0	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.0	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.0	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.0	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.0	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.0	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.2	GO:0017158	regulation of calcium ion-dependent exocytosis(GO:0017158)
0.0	0.0	GO:0046621	negative regulation of organ growth(GO:0046621)
0.0	0.3	GO:0071805	cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0	0.0	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0019226	transmission of nerve impulse(GO:0019226) multicellular organismal signaling(GO:0035637)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	1.0	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.0	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.0	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0	0.0	GO:0008615	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.2	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.0	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.0	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0009067	aspartate family amino acid biosynthetic process(GO:0009067)
0.0	0.1	GO:0007271	synaptic transmission, cholinergic(GO:0007271)
0.0	0.0	GO:0030252	growth hormone secretion(GO:0030252)
0.0	0.0	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0006385	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.1	GO:0051349	positive regulation of lyase activity(GO:0051349)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0048265	response to pain(GO:0048265)
0.0	0.0	GO:0071732	cellular response to nitric oxide(GO:0071732) cellular response to reactive nitrogen species(GO:1902170)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.0	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0040018	positive regulation of multicellular organism growth(GO:0040018)
0.0	1.3	GO:0006936	muscle contraction(GO:0006936)
0.0	0.0	GO:0047496	vesicle transport along microtubule(GO:0047496) vesicle cytoskeletal trafficking(GO:0099518)
0.0	0.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0045026	plasma membrane fusion(GO:0045026)
0.0	0.0	GO:0009125	nucleoside monophosphate catabolic process(GO:0009125)
0.0	0.0	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0	0.0	GO:0044068	modulation by virus of host process(GO:0019054) modulation by symbiont of host cellular process(GO:0044068)
0.0	0.7	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.0	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5	5.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4	3.4	GO:0005614	interstitial matrix(GO:0005614)
0.4	1.2	GO:0043259	laminin-10 complex(GO:0043259)
0.3	0.9	GO:0071438	invadopodium membrane(GO:0071438)
0.3	1.7	GO:0016012	sarcoglycan complex(GO:0016012)
0.3	0.8	GO:0070852	cell body fiber(GO:0070852)
0.3	1.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3	1.0	GO:0005606	laminin-1 complex(GO:0005606)
0.3	0.8	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	0.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	0.7	GO:0030056	hemidesmosome(GO:0030056)
0.2	0.3	GO:0071437	invadopodium(GO:0071437)
0.2	0.7	GO:0032059	bleb(GO:0032059)
0.2	0.7	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	0.5	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.2	1.1	GO:0098645	network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1	1.7	GO:0005581	collagen trimer(GO:0005581)
0.1	0.8	GO:0016342	catenin complex(GO:0016342)
0.1	1.3	GO:0030315	T-tubule(GO:0030315)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0043083	synaptic cleft(GO:0043083)
0.1	1.0	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	0.6	GO:0001527	microfibril(GO:0001527)
0.1	0.3	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.8	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1	0.3	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	1.0	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1	0.3	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.7	GO:0014704	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.2	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1	0.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.3	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	1.4	GO:0005811	lipid particle(GO:0005811)
0.1	0.4	GO:0010369	chromocenter(GO:0010369)
0.1	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.3	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.4	GO:0030673	axolemma(GO:0030673)
0.1	0.2	GO:0044215	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.1	4.5	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1	0.3	GO:0031211	palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1	15.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	2.7	GO:0031012	extracellular matrix(GO:0031012)
0.1	1.0	GO:0001725	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.1	0.1	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1	1.1	GO:0005796	Golgi lumen(GO:0005796)
0.1	0.4	GO:0032589	neuron projection membrane(GO:0032589)
0.1	0.8	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	1.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	1.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	3.9	GO:0030016	myofibril(GO:0030016)
0.0	0.5	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.1	GO:0002139	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.2	GO:0043198	dendritic shaft(GO:0043198)
0.0	5.7	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.3	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	2.7	GO:0008076	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0	1.7	GO:0030426	growth cone(GO:0030426)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	1.1	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0000125	PCAF complex(GO:0000125)
0.0	6.7	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.6	GO:0019861	obsolete flagellum(GO:0019861)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.0	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.8	GO:0016459	myosin complex(GO:0016459)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0030427	site of polarized growth(GO:0030427)
0.0	0.1	GO:0030681	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	2.3	GO:0016324	apical plasma membrane(GO:0016324)
0.0	0.2	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.0	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.5	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)
0.0	0.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0042641	actomyosin(GO:0042641)
0.0	0.3	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.0	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.0	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.4	4.2	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.4	1.3	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.4	1.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.4	1.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.4	1.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	1.3	GO:0043559	insulin binding(GO:0043559)
0.3	0.9	GO:0070052	collagen V binding(GO:0070052)
0.3	3.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.3	0.8	GO:0002162	dystroglycan binding(GO:0002162)
0.3	2.5	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.3	3.3	GO:0004065	arylsulfatase activity(GO:0004065)
0.3	0.3	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.3	1.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.3	0.8	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.7	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2	1.6	GO:0043274	phospholipase binding(GO:0043274)
0.2	1.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	1.1	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2	0.6	GO:0042577	lipid phosphatase activity(GO:0042577)
0.2	0.6	GO:0034056	estrogen response element binding(GO:0034056)
0.2	0.6	GO:0001601	peptide YY receptor activity(GO:0001601)
0.2	0.4	GO:0005113	patched binding(GO:0005113)
0.2	0.6	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.2	2.7	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	0.6	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2	0.8	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.4	GO:0048185	activin binding(GO:0048185)
0.2	1.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2	0.5	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.2	1.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.2	0.7	GO:0048495	Roundabout binding(GO:0048495)
0.2	2.1	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.2	0.5	GO:0070324	thyroid hormone binding(GO:0070324)
0.2	0.7	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.2	0.3	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	0.8	GO:0042805	actinin binding(GO:0042805)
0.2	0.5	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.2	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	1.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	3.1	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	0.9	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.4	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.4	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1	0.6	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.6	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	3.4	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.7	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.1	2.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.5	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.3	GO:0050693	LBD domain binding(GO:0050693)
0.1	0.8	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.1	0.8	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.9	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.3	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.3	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.5	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	5.8	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.2	GO:0048018	receptor agonist activity(GO:0048018)
0.1	1.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.1	0.3	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1	0.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	0.3	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	1.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.1	0.4	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1	1.2	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1	0.9	GO:0030553	cGMP binding(GO:0030553)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.2	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.1	0.3	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	1.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.1	0.2	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.1	0.5	GO:0048019	receptor antagonist activity(GO:0048019)
0.1	0.8	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.3	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.2	GO:0017166	vinculin binding(GO:0017166)
0.1	0.8	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.1	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	1.3	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	0.4	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.5	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.4	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.7	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.1	0.4	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.1	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.2	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.1	0.3	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1	1.0	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	0.3	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.2	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	0.2	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1	0.3	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1	0.5	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.6	GO:0003711	obsolete transcription elongation regulator activity(GO:0003711)
0.1	0.2	GO:0030343	vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1	0.5	GO:0051378	serotonin binding(GO:0051378)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.2	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	1.1	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.1	0.1	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.1	0.4	GO:0030506	ankyrin binding(GO:0030506)
0.1	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.3	GO:0019966	interleukin-1 binding(GO:0019966)
0.1	0.3	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.1	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	0.3	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.1	GO:0043175	RNA polymerase core enzyme binding(GO:0043175)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.8	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.6	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.3	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.2	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	1.1	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.5	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.7	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.0	GO:0050682	AF-2 domain binding(GO:0050682)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.2	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	3.3	GO:0008201	heparin binding(GO:0008201)
0.0	0.2	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.2	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.6	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.2	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.2	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.2	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.2	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.2	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	1.0	GO:0001948	glycoprotein binding(GO:0001948)
0.0	0.4	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.3	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.2	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.2	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.4	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	1.2	GO:0005178	integrin binding(GO:0005178)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	1.3	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.1	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0005221	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0	0.7	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.2	GO:0030492	hemoglobin binding(GO:0030492)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	8.0	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.3	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.3	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.2	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.0	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.5	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.2	GO:0001077	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.5	GO:0005158	insulin receptor binding(GO:0005158)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.0	GO:0035198	miRNA binding(GO:0035198)
0.0	0.3	GO:0005248	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0	2.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.5	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	0.1	GO:0045502	dynein binding(GO:0045502)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	1.4	GO:0004497	monooxygenase activity(GO:0004497)
0.0	0.1	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0034187	obsolete apolipoprotein E binding(GO:0034187)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0	0.3	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0015211	purine nucleoside transmembrane transporter activity(GO:0015211)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.1	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0	0.1	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.6	GO:0008235	metalloexopeptidase activity(GO:0008235)
0.0	0.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0	0.0	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0016679	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.0	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.0	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.0	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.2	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	1.6	GO:0008083	growth factor activity(GO:0008083)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	1.1	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.0	0.1	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.0	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.4	GO:0004435	phosphatidylinositol phospholipase C activity(GO:0004435)
0.0	0.0	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.1	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.0	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.5	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.0	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.1	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.0	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.0	GO:0070063	RNA polymerase binding(GO:0070063)
0.0	0.1	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.2	8.1	NABA COLLAGENS	Genes encoding collagen proteins
0.2	1.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	6.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	1.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	4.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.1	2.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	0.2	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.1	12.1	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.4	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	3.3	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	0.5	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.2	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1	0.5	PID ALK2 PATHWAY	ALK2 signaling events
0.0	1.0	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	1.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	1.4	PID BMP PATHWAY	BMP receptor signaling
0.0	1.1	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	1.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	9.1	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	1.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	1.2	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	1.3	PID FGF PATHWAY	FGF signaling pathway
0.0	0.2	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.4	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.0	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	1.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.1	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.2	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.6	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.1	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.3	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.0	PID IFNG PATHWAY	IFN-gamma pathway
0.0	0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.2	6.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	0.2	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2	2.3	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	2.0	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	0.2	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.2	0.5	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.8	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	1.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.9	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1	7.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.8	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	1.9	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	0.1	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.1	1.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.1	2.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.2	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.1	0.1	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.1	1.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.1	0.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.9	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	1.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.7	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.0	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	0.5	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1	1.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.1	0.9	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.2	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	0.1	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	0.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.1	0.7	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.1	2.4	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events
0.0	0.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	1.2	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.1	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.4	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.6	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.5	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.2	REACTOME PI3K EVENTS IN ERBB4 SIGNALING	Genes involved in PI3K events in ERBB4 signaling
0.0	0.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.9	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.7	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.8	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.8	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	1.0	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION	Genes involved in Regulation of Insulin Secretion
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.6	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.0	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	2.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.0	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.0	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.0	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.1	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.2	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.1	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.0	0.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.1	REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D	Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)

Results for IRF7

Z-value: 4.12

Motif logo

Transcription factors associated with IRF7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IRF7 motif across conditions

Conditions sorted by the z-value of the IRF7 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: