Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for IRX2

Z-value: 2.00

Motif logo

logo of

Transcription factors associated with IRX2

Gene Symbol Gene ID Gene Info
IRX2
ENSG00000170561.8 iroquois homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_2658384_2658535IRX2933100.089867-0.491.8e-01Click!
chr5_2743001_2743152IRX286930.252154-0.481.9e-01Click!
chr5_2743925_2744106IRX277540.254816-0.462.1e-01Click!
chr5_2743463_2743805IRX281350.253667-0.412.7e-01Click!
chr5_2748918_2749069IRX227760.313498-0.412.7e-01Click!

Activity of the IRX2 motif across conditions

Conditions sorted by the z-value of the IRX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_59235574_59235725 0.64 RP11-136H19.1
22324
 0.2
chr13_24145710_24146057 0.63 TNFRSF19
 tumor necrosis factor receptor superfamily, member 19
 1080
 0.66
chr4_86700210_86700446 0.61 ARHGAP24
 Rho GTPase activating protein 24
 469
 0.88
chr2_191044944_191045899 0.56 C2orf88
 chromosome 2 open reading frame 88
 168
 0.96
chr4_114680367_114680518 0.55 CAMK2D
 calcium/calmodulin-dependent protein kinase II delta
 1782
 0.52
chr2_189839524_189839773 0.54 COL3A1
 collagen, type III, alpha 1
 549
 0.79
chr12_91504813_91504964 0.54 LUM
 lumican
 720
 0.73
chr6_107814282_107814433 0.54 SOBP
 sine oculis binding protein homolog (Drosophila)
 3195
 0.27
chr10_17273946_17274204 0.53 VIM
 vimentin
 1467
 0.3
chr7_19154676_19154916 0.52 TWIST1
 twist family bHLH transcription factor 1
 2499
 0.21
chr11_47545333_47545710 0.52 CELF1
 CUGBP, Elav-like family member 1
 19
 0.95
chrX_45634159_45634477 0.51 ENSG00000207725
 .
 27788
 0.21
chr18_65337814_65337965 0.51 DSEL
 dermatan sulfate epimerase-like
 153672
 0.04
chr2_189840001_189840152 0.50 COL3A1
 collagen, type III, alpha 1
 977
 0.57
chr4_181928306_181928668 0.50 ENSG00000251742
 .
 827774
 0.0
chr1_8456361_8456512 0.50 RERE
 arginine-glutamic acid dipeptide (RE) repeats
 27290
 0.16
chr7_19154419_19154620 0.50 AC003986.6
2422
 0.22
chr6_131360061_131360448 0.50 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 23272
 0.26
chr4_170175719_170175897 0.49 SH3RF1
 SH3 domain containing ring finger 1
 15300
 0.25
chr4_81192543_81192855 0.49 FGF5
 fibroblast growth factor 5
 4906
 0.28
chr3_173302672_173303490 0.48 NLGN1
 neuroligin 1
 371
 0.93
chr19_15362877_15363312 0.47 EPHX3
 epoxide hydrolase 3
 18848
 0.15
chr1_111817109_111817317 0.47 CHIAP2
 chitinase, acidic pseudogene 2
 5469
 0.15
chr10_63212172_63213035 0.47 RP11-809M12.1
206
 0.83
chr2_20261222_20261477 0.46 RP11-644K8.1
9454
 0.17
chr4_140187126_140187277 0.46 ENSG00000206722
 .
 9287
 0.13
chr9_36031560_36031711 0.46 RECK
 reversion-inducing-cysteine-rich protein with kazal motifs
 4795
 0.23
chr17_39265148_39265305 0.46 KRTAP4-9
 keratin associated protein 4-9
 3642
 0.08
chr7_151433344_151433930 0.45 PRKAG2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 237
 0.95
chr1_110932873_110933043 0.45 SLC16A4
 solute carrier family 16, member 4
 690
 0.57
chr4_81193524_81193675 0.45 FGF5
 fibroblast growth factor 5
 5806
 0.27
chr3_184504176_184504876 0.45 VPS8
 vacuolar protein sorting 8 homolog (S. cerevisiae)
 25405
 0.22
chr11_94529113_94529270 0.45 AMOTL1
 angiomotin like 1
 27654
 0.2
chr5_158127257_158127408 0.45 CTD-2363C16.1
282682
 0.01
chr1_197663527_197663678 0.45 ENSG00000207139
 .
 8732
 0.24
chr7_85402414_85402565 0.45 SEMA3D
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
 586318
 0.0
chr5_16933613_16934070 0.45 MYO10
 myosin X
 2206
 0.34
chr8_19459992_19460252 0.45 CSGALNACT1
 chondroitin sulfate N-acetylgalactosaminyltransferase 1
 116
 0.98
chr6_56573707_56573932 0.44 DST
 dystonin
 66025
 0.13
chr12_100986991_100987142 0.44 GAS2L3
 growth arrest-specific 2 like 3
 330
 0.92
chr6_112359418_112359743 0.44 WISP3
 WNT1 inducible signaling pathway protein 3
 15695
 0.2
chr21_30503915_30504153 0.44 MAP3K7CL
 MAP3K7 C-terminal like
 456
 0.76
chr1_224803774_224804760 0.43 CNIH3
 cornichon family AMPA receptor auxiliary protein 3
 272
 0.57
chr10_95274973_95275229 0.43 ENSG00000212396
 .
 4664
 0.19
chr17_48347595_48347940 0.43 TMEM92
 transmembrane protein 92
 1000
 0.43
chr2_12746713_12746934 0.43 TRIB2
 tribbles pseudokinase 2
 110192
 0.07
chr2_155001115_155001266 0.43 ENSG00000266512
 .
 1530
 0.54
chr3_173400678_173400829 0.43 NLGN1
 neuroligin 1
 78364
 0.12
chr5_120114861_120115414 0.42 ENSG00000222609
 .
 68602
 0.14
chr1_86846406_86846595 0.42 ODF2L
 outer dense fiber of sperm tails 2-like
 2379
 0.36
chr1_10238848_10238999 0.42 ENSG00000201746
 .
 15597
 0.16
chr4_31460428_31460579 0.42 RP11-619J20.1
664911
 0.0
chr5_121921903_121922054 0.41 CTC-210G5.1
107196
 0.07
chr8_119809234_119809385 0.41 TNFRSF11B
 tumor necrosis factor receptor superfamily, member 11b
 155130
 0.04
chr4_88895012_88895192 0.41 SPP1
 secreted phosphoprotein 1
 1717
 0.37
chr20_4206792_4206961 0.40 ADRA1D
 adrenoceptor alpha 1D
 22845
 0.19
chr10_27988621_27988772 0.40 MKX
 mohawk homeobox
 43778
 0.15
chr15_48351886_48352188 0.40 SLC24A5
 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
 61132
 0.12
chr15_81619593_81619928 0.40 RP11-761I4.3
2981
 0.23
chr12_15854596_15854955 0.40 EPS8
 epidermal growth factor receptor pathway substrate 8
 11152
 0.24
chr9_113530116_113530340 0.40 MUSK
 muscle, skeletal, receptor tyrosine kinase
 7399
 0.3
chr19_50006575_50006747 0.39 ENSG00000207782
 .
 2536
 0.08
chr14_45711437_45711895 0.39 MIS18BP1
 MIS18 binding protein 1
 10714
 0.2
chr5_131893791_131893942 0.39 RAD50
 RAD50 homolog (S. cerevisiae)
 943
 0.42
chr7_128471351_128471889 0.39 FLNC
 filamin C, gamma
 1140
 0.39
chrX_78003789_78003940 0.39 LPAR4
 lysophosphatidic acid receptor 4
 636
 0.83
chr9_18476160_18476529 0.39 ADAMTSL1
 ADAMTS-like 1
 2113
 0.45
chr2_25745171_25745351 0.39 AC104699.1
101275
 0.07
chr18_12934696_12934877 0.39 PTPN2
 protein tyrosine phosphatase, non-receptor type 2
 5144
 0.21
chr5_148793966_148794117 0.39 ENSG00000208035
 .
 14440
 0.12
chr22_43396400_43396551 0.39 PACSIN2
 protein kinase C and casein kinase substrate in neurons 2
 1971
 0.35
chr15_33009554_33009932 0.39 GREM1
 gremlin 1, DAN family BMP antagonist
 432
 0.84
chr1_231014941_231015092 0.38 RP5-858B6.3
4424
 0.14
chr10_28287180_28287375 0.38 ARMC4
 armadillo repeat containing 4
 700
 0.81
chr12_21652771_21652922 0.38 RECQL
 RecQ protein-like (DNA helicase Q1-like)
 1639
 0.29
chr10_28003601_28003790 0.38 MKX
 mohawk homeobox
 28779
 0.18
chr1_161991242_161991393 0.38 OLFML2B
 olfactomedin-like 2B
 2113
 0.38
chr4_138446425_138446576 0.38 PCDH18
 protocadherin 18
 7065
 0.34
chr4_79442125_79442276 0.38 ANXA3
 annexin A3
 30473
 0.21
chr2_66809839_66810137 0.38 MEIS1
 Meis homeobox 1
 73929
 0.12
chr7_6296015_6296815 0.38 CYTH3
 cytohesin 3
 15860
 0.17
chr12_29744562_29745018 0.37 TMTC1
 transmembrane and tetratricopeptide repeat containing 1
 12367
 0.26
chr20_58164973_58165317 0.37 PHACTR3
 phosphatase and actin regulator 3
 12581
 0.25
chr9_126270283_126270454 0.37 RP11-230L22.4
16205
 0.24
chr7_82071524_82071810 0.37 CACNA2D1
 calcium channel, voltage-dependent, alpha 2/delta subunit 1
 1364
 0.61
chr5_38651585_38651790 0.37 LIFR
 leukemia inhibitory factor receptor alpha
 56181
 0.13
chr7_148543528_148543679 0.37 ENSG00000251712
 .
 25499
 0.15
chr5_92948054_92948286 0.37 ENSG00000251725
 .
 8324
 0.21
chr11_27406370_27406521 0.37 CCDC34
 coiled-coil domain containing 34
 21030
 0.22
chr3_157639138_157639289 0.37 ENSG00000251751
 .
 9301
 0.31
chr3_187984346_187984497 0.37 LPP
 LIM domain containing preferred translocation partner in lipoma
 26769
 0.24
chrX_33227749_33227900 0.37 DMD
 dystrophin
 1605
 0.57
chr15_49757030_49757181 0.37 FGF7
 fibroblast growth factor 7
 41648
 0.17
chr8_12808711_12809195 0.37 KIAA1456
 KIAA1456
 112
 0.98
chr12_18536230_18536431 0.37 PIK3C2G
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
 101352
 0.08
chr3_79346003_79346154 0.37 ENSG00000265193
 .
 210959
 0.02
chr16_69309884_69310035 0.36 RP11-343C2.11
 Uncharacterized protein
 23626
 0.1
chr19_17493310_17493461 0.36 PLVAP
 plasmalemma vesicle associated protein
 5226
 0.09
chr5_9698511_9698662 0.36 TAS2R1
 taste receptor, type 2, member 1
 13726
 0.22
chr10_88558549_88558700 0.36 BMPR1A
 bone morphogenetic protein receptor, type IA
 42217
 0.12
chr8_23110355_23110506 0.36 CHMP7
 charged multivesicular body protein 7
 6258
 0.13
chr9_21688149_21688723 0.36 ENSG00000244230
 .
 10877
 0.24
chr5_111090218_111090459 0.36 NREP
 neuronal regeneration related protein
 1610
 0.42
chrY_7395772_7396011 0.36 ENSG00000252472
 .
 104692
 0.07
chr15_95870278_95870659 0.36 ENSG00000222076
 .
 418565
 0.01
chr15_39464989_39465402 0.36 RP11-624L4.1
54281
 0.16
chr7_15956823_15957170 0.35 MEOX2
 mesenchyme homeobox 2
 230559
 0.02
chr8_117902329_117902480 0.35 RAD21
 RAD21 homolog (S. pombe)
 15299
 0.15
chr7_115275599_115275750 0.35 ENSG00000202377
 .
 54178
 0.18
chr14_68591878_68592029 0.35 CTD-2566J3.1
4960
 0.26
chr7_111721329_111721542 0.35 DOCK4
 dedicator of cytokinesis 4
 77249
 0.11
chr2_145253540_145253691 0.35 ZEB2
 zinc finger E-box binding homeobox 2
 21500
 0.22
chr4_113810751_113811050 0.35 RP11-119H12.6
7414
 0.26
chr7_120630679_120630951 0.35 CPED1
 cadherin-like and PC-esterase domain containing 1
 1139
 0.51
chr2_189839242_189839495 0.35 COL3A1
 collagen, type III, alpha 1
 269
 0.92
chr16_82031521_82031672 0.35 SDR42E1
 short chain dehydrogenase/reductase family 42E, member 1
 13490
 0.18
chr13_49063065_49063216 0.35 RCBTB2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
 44073
 0.16
chr1_234721273_234721435 0.35 ENSG00000212144
 .
 7667
 0.2
chr4_160170135_160170337 0.35 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 17797
 0.23
chr11_62312562_62314176 0.34 RP11-864I4.4
102
 0.64
chr6_119069398_119069957 0.34 CEP85L
 centrosomal protein 85kDa-like
 38439
 0.19
chrX_114847371_114847522 0.34 PLS3
 plastin 3
 2891
 0.3
chr2_197852125_197852688 0.34 ANKRD44
 ankyrin repeat domain 44
 12820
 0.25
chr4_124776288_124776439 0.34 SPRY1
 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
 455240
 0.01
chr7_79820122_79820273 0.34 GNAI1
 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
 3822
 0.32
chr16_1665562_1665745 0.34 CRAMP1L
 Crm, cramped-like (Drosophila)
 1012
 0.35
chr10_93391857_93392062 0.34 PPP1R3C
 protein phosphatase 1, regulatory subunit 3C
 852
 0.74
chr5_16995186_16995337 0.34 ENSG00000201436
 .
 53201
 0.13
chr18_53002568_53002719 0.34 TCF4
 transcription factor 4
 13118
 0.28
chr19_47393595_47393746 0.34 ARHGAP35
 Rho GTPase activating protein 35
 28263
 0.14
chr9_80366312_80366540 0.33 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 71489
 0.12
chr5_32441809_32441985 0.33 ZFR
 zinc finger RNA binding protein
 2970
 0.29
chr7_80337041_80337192 0.33 CD36
 CD36 molecule (thrombospondin receptor)
 34424
 0.24
chr20_8369139_8369290 0.33 PLCB1-IT1
 PLCB1 intronic transcript 1 (non-protein coding)
 139842
 0.05
chr7_111724737_111724893 0.33 DOCK4
 dedicator of cytokinesis 4
 80629
 0.1
chr11_57045246_57045411 0.33 APLNR
 apelin receptor
 40653
 0.09
chr4_134071254_134071890 0.33 PCDH10
 protocadherin 10
 1102
 0.7
chr1_179853714_179853914 0.33 TOR1AIP1
 torsin A interacting protein 1
 1790
 0.28
chr4_85612483_85612685 0.33 ENSG00000239466
 .
 3413
 0.31
chr6_122253515_122253742 0.33 ENSG00000199932
 .
 279166
 0.01
chr6_131254800_131254951 0.33 EPB41L2
 erythrocyte membrane protein band 4.1-like 2
 22750
 0.26
chr13_98506009_98506160 0.32 ENSG00000238407
 .
 31979
 0.23
chr3_105237619_105237770 0.32 ALCAM
 activated leukocyte cell adhesion molecule
 5525
 0.35
chr4_113811114_113811345 0.32 RP11-119H12.6
7743
 0.26
chr12_66274900_66275108 0.32 RP11-366L20.2
 Uncharacterized protein
 354
 0.87
chr3_25476812_25476963 0.32 RARB
 retinoic acid receptor, beta
 7085
 0.29
chr1_119529511_119529803 0.32 TBX15
 T-box 15
 771
 0.75
chr4_159565765_159565953 0.32 C4orf46
 chromosome 4 open reading frame 46
 27185
 0.15
chr3_115078299_115078524 0.32 ZBTB20
 zinc finger and BTB domain containing 20
 212293
 0.02
chr7_34147255_34147406 0.32 ENSG00000202431
 .
 189880
 0.03
chr13_51363166_51363317 0.32 DLEU7-AS1
 DLEU7 antisense RNA 1
 18751
 0.19
chr10_69831641_69832005 0.32 HERC4
 HECT and RLD domain containing E3 ubiquitin protein ligase 4
 2071
 0.33
chr4_129376053_129376269 0.32 PGRMC2
 progesterone receptor membrane component 2
 166177
 0.04
chr6_108943623_108943921 0.32 FOXO3
 forkhead box O3
 33777
 0.22
chr7_28387506_28387665 0.32 CREB5
 cAMP responsive element binding protein 5
 48645
 0.18
chr2_133835049_133835200 0.32 AC011755.1
 HCG2006742; Protein LOC100996685
 39453
 0.21
chr9_77762612_77762996 0.32 ENSG00000200041
 .
 33733
 0.15
chr6_158424356_158424607 0.32 SYNJ2-IT1
 SYNJ2 intronic transcript 1 (non-protein coding)
 2342
 0.3
chr20_20054311_20054462 0.32 C20orf26
 chromosome 20 open reading frame 26
 150
 0.96
chrX_65856771_65857070 0.31 EDA2R
 ectodysplasin A2 receptor
 1963
 0.45
chrX_135258076_135258227 0.31 FHL1
 four and a half LIM domains 1
 6066
 0.24
chr7_37960238_37961117 0.31 EPDR1
 ependymin related 1
 245
 0.94
chr9_16752970_16753121 0.31 BNC2
 basonuclin 2
 24833
 0.21
chr18_9797298_9797449 0.31 ENSG00000242651
 .
 33251
 0.16
chr4_177484526_177484677 0.31 RP11-313E19.2
106171
 0.07
chr9_95258995_95259146 0.31 ASPN
 asporin
 14282
 0.17
chr6_83076044_83076195 0.31 TPBG
 trophoblast glycoprotein
 2158
 0.46
chr17_40155302_40155453 0.31 DNAJC7
 DnaJ (Hsp40) homolog, subfamily C, member 7
 7916
 0.11
chr9_16867910_16868386 0.31 BNC2
 basonuclin 2
 2556
 0.42
chr1_172109829_172110023 0.31 ENSG00000207949
 .
 1879
 0.31
chr8_89340038_89340774 0.31 MMP16
 matrix metallopeptidase 16 (membrane-inserted)
 152
 0.73
chr9_16704821_16704987 0.30 BNC2
 basonuclin 2
 176
 0.96
chr1_94791068_94791245 0.30 ARHGAP29
 Rho GTPase activating protein 29
 87967
 0.08
chr8_121869953_121870264 0.30 SNTB1
 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
 44595
 0.16
chr4_3012533_3012710 0.30 ENSG00000199335
 .
 33207
 0.12
chr6_113886463_113886648 0.30 ENSG00000266650
 .
 37562
 0.19
chr20_53092813_53093232 0.30 DOK5
 docking protein 5
 765
 0.8
chr1_95330057_95330663 0.30 SLC44A3
 solute carrier family 44, member 3
 2527
 0.28
chr5_95555988_95556139 0.30 ENSG00000206997
 .
 10132
 0.29
chr15_49715580_49715731 0.30 FGF7
 fibroblast growth factor 7
 198
 0.96
chr4_107222786_107222937 0.30 TBCK
 TBC1 domain containing kinase
 8884
 0.24
chr12_91570174_91570436 0.30 DCN
 decorin
 2024
 0.44
chr5_121411439_121411590 0.30 LOX
 lysyl oxidase
 2466
 0.34
chr12_3813953_3814160 0.30 ENSG00000222338
 .
 21437
 0.23
chr5_143229994_143230145 0.30 HMHB1
 histocompatibility (minor) HB-1
 38343
 0.22
chr13_36045598_36045825 0.30 MAB21L1
 mab-21-like 1 (C. elegans)
 5121
 0.22
chr2_32878093_32878244 0.30 ENSG00000265057
 .
 17846
 0.22
chr10_6807939_6808090 0.30 PRKCQ
 protein kinase C, theta
 185751
 0.03
chr10_30504590_30504756 0.30 ENSG00000200887
 .
 83929
 0.09
chr8_72775684_72775924 0.30 MSC
 musculin
 19101
 0.17
chr1_170677041_170677192 0.29 PRRX1
 paired related homeobox 1
 44038
 0.19
chr2_158113918_158114875 0.29 GALNT5
 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
 286
 0.93
chr1_86049499_86049650 0.29 CYR61
 cysteine-rich, angiogenic inducer, 61
 3130
 0.24
chr8_97350778_97351015 0.29 ENSG00000199732
 .
 29346
 0.17
chr10_95848621_95848951 0.29 PLCE1
 phospholipase C, epsilon 1
 44
 0.97
chr15_32928578_32928729 0.29 SCG5
 secretogranin V (7B2 protein)
 5224
 0.15
chr1_96354702_96354941 0.29 ENSG00000221798
 .
 2725
 0.41
chr15_67021750_67022170 0.29 SMAD6
 SMAD family member 6
 17925
 0.24
chr5_77805493_77806187 0.29 LHFPL2
 lipoma HMGIC fusion partner-like 2
 39134
 0.21
chr9_82272755_82272906 0.29 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 5322
 0.36

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.6 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.2 0.6 GO:0030210 heparin biosynthetic process(GO:0030210)
0.2 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 0.7 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2 0.3 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 1.2 GO:0097435 extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.2 0.5 GO:0002689 negative regulation of leukocyte chemotaxis(GO:0002689)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.4 GO:0071694 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:0016246 RNA interference(GO:0016246)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.1 0.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1 0.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0048149 behavioral response to ethanol(GO:0048149)
0.1 0.2 GO:1905209 positive regulation of cardioblast differentiation(GO:0051891) positive regulation of cardiocyte differentiation(GO:1905209)
0.1 0.2 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0060013 righting reflex(GO:0060013)
0.1 0.2 GO:0031394 regulation of prostaglandin biosynthetic process(GO:0031392) positive regulation of prostaglandin biosynthetic process(GO:0031394) regulation of unsaturated fatty acid biosynthetic process(GO:2001279) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0045978 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1 0.1 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.1 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.1 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.1 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.1 0.1 GO:1904238 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.1 0.3 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.3 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1 0.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.3 GO:2000144 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 0.1 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.1 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.2 GO:0060992 response to fungicide(GO:0060992)
0.1 0.3 GO:0001878 response to yeast(GO:0001878)
0.1 0.1 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.1 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.2 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.1 0.2 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.2 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.2 GO:0060638 mesenchymal-epithelial cell signaling(GO:0060638)
0.1 0.3 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0051280 negative regulation of ion transmembrane transporter activity(GO:0032413) negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284) negative regulation of calcium ion transmembrane transport(GO:1903170)
0.1 0.1 GO:0060437 lung growth(GO:0060437)
0.1 0.1 GO:0010667 striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:0071801 regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0060004 reflex(GO:0060004)
0.0 0.1 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0097061 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.2 GO:0061004 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.2 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.9 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.0 GO:0072070 loop of Henle development(GO:0072070)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0070366 regulation of hepatocyte differentiation(GO:0070366)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.1 GO:0048368 lateral mesoderm development(GO:0048368)
0.0 0.1 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.1 GO:0090190 positive regulation of mesonephros development(GO:0061213) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.0 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0046040 IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0 0.1 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.1 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.1 GO:0009128 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:0090399 replicative senescence(GO:0090399)
0.0 0.3 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0060242 contact inhibition(GO:0060242)
0.0 0.0 GO:0060996 dendritic spine development(GO:0060996)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0060073 urinary bladder smooth muscle contraction(GO:0014832) micturition(GO:0060073) smooth muscle contraction involved in micturition(GO:0060083)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.6 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.4 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.2 GO:0043113 receptor clustering(GO:0043113)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0072677 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.0 GO:0002246 wound healing involved in inflammatory response(GO:0002246) inflammatory response to wounding(GO:0090594)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.2 GO:0033158 regulation of protein import into nucleus, translocation(GO:0033158)
0.0 0.1 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.2 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0007097 nuclear migration(GO:0007097)
0.0 0.4 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0033483 gas homeostasis(GO:0033483)
0.0 0.1 GO:0090030 regulation of steroid hormone biosynthetic process(GO:0090030)
0.0 0.1 GO:0003214 cardiac left ventricle morphogenesis(GO:0003214)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0060841 venous blood vessel development(GO:0060841)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0 1.3 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.0 GO:0060433 bronchus development(GO:0060433) smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0 0.1 GO:0051154 negative regulation of striated muscle cell differentiation(GO:0051154)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.0 0.1 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.0 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.0 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.0 GO:0033860 obsolete regulation of natriuresis(GO:0003078) regulation of NAD(P)H oxidase activity(GO:0033860)
0.0 0.0 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.1 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.1 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.0 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0015811 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.1 GO:0008215 spermine metabolic process(GO:0008215)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:2000053 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.1 GO:0010324 phagocytosis, engulfment(GO:0006911) membrane invagination(GO:0010324)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.0 GO:0060913 cardiac cell fate determination(GO:0060913)
0.0 0.2 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.0 GO:1901798 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0010657 muscle cell apoptotic process(GO:0010657) regulation of muscle cell apoptotic process(GO:0010660)
0.0 0.0 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.0 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.0 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0 0.1 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.1 GO:0046184 aldehyde biosynthetic process(GO:0046184)
0.0 0.1 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.0 0.0 GO:0010842 retina layer formation(GO:0010842)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0006573 valine metabolic process(GO:0006573)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0002076 osteoblast development(GO:0002076)
0.0 0.0 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.0 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.0 0.1 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.0 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.0 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.0 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.1 GO:0030146 obsolete diuresis(GO:0030146)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.0 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.0 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.0 GO:0045901 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.0 0.0 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.0 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0031054 pre-miRNA processing(GO:0031054)
0.0 0.1 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.0 GO:0034393 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.0 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.0 GO:0051969 regulation of transmission of nerve impulse(GO:0051969)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0061298 retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.0 GO:0042637 catagen(GO:0042637)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.0 GO:0034442 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0080111 DNA demethylation(GO:0080111)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.0 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.0 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.2 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of wound healing(GO:0061045) negative regulation of hemostasis(GO:1900047)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.0 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.0 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.0 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.0 GO:0006533 aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.5 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.3 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0001527 microfibril(GO:0001527)
0.1 0.7 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0008091 spectrin(GO:0008091)
0.0 0.3 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.8 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0030288 outer membrane-bounded periplasmic space(GO:0030288) periplasmic space(GO:0042597)
0.0 0.1 GO:0036126 outer dense fiber(GO:0001520) sperm flagellum(GO:0036126)
0.0 0.9 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.3 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.1 GO:0002102 podosome(GO:0002102)
0.0 0.9 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.0 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 2.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.6 GO:0030016 myofibril(GO:0030016)
0.0 0.0 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0001099 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.2 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.2 1.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.5 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0043274 phospholipase binding(GO:0043274)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.3 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.1 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0004739 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.2 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.3 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.0 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0044620 ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process(GO:0000036) ACP phosphopantetheine attachment site binding(GO:0044620) prosthetic group binding(GO:0051192)
0.0 0.1 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:1990939 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0 0.2 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.0 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.0 GO:0008061 chitin binding(GO:0008061)
0.0 0.2 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.0 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.0 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.0 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.1 GO:0045502 dynein binding(GO:0045502)
0.0 0.0 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.0 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.0 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.0 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.1 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.0 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.0 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.1 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.8 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 0.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME PI3K EVENTS IN ERBB4 SIGNALING Genes involved in PI3K events in ERBB4 signaling
0.0 0.0 REACTOME KINESINS Genes involved in Kinesins