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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for IRX3

Z-value: 2.33

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Transcription factors associated with IRX3

Gene Symbol	Gene ID	Gene Info
IRX3 Ensembl NCBI GeneCards UniProt	ENSG00000177508.11	iroquois homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_54322323_54322474	IRX3	1723	0.443494	0.63	6.7e-02	Click!
chr16_54324317_54324468	IRX3	3717	0.298055	0.57	1.1e-01	Click!
chr16_54408198_54408422	IRX3	87635	0.093349	0.42	2.6e-01	Click!
chr16_54324112_54324263	IRX3	3512	0.304059	-0.38	3.1e-01	Click!
chr16_54407600_54408115	IRX3	87182	0.093969	-0.30	4.4e-01	Click!

Activity of the IRX3 motif across conditions

Conditions sorted by the z-value of the IRX3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr21_30503915_30504153	1.21	MAP3K7CL	MAP3K7 C-terminal like	456	0.76
chr12_59312115_59312531	1.15	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1004	0.56
chr7_120630679_120630951	1.12	CPED1	cadherin-like and PC-esterase domain containing 1	1139	0.51
chr5_88168642_88169029	1.12	MEF2C	myocyte enhancer factor 2C	4959	0.27
chr5_71543858_71544009	1.10	ENSG00000244748	.	66582	0.09
chr17_65208623_65208774	1.10	RP11-401F2.4		11721	0.16
chr19_30468967_30469148	1.05	URI1	URI1, prefoldin-like chaperone	7057	0.32
chr13_22597456_22597607	1.04	ENSG00000244197	.	232855	0.02
chr4_138450227_138450378	1.03	PCDH18	protocadherin 18	3263	0.41
chr9_18476160_18476529	1.03	ADAMTSL1	ADAMTS-like 1	2113	0.45
chr17_49125743_49125894	0.95	SPAG9	sperm associated antigen 9	1579	0.36
chr18_32239428_32239737	0.94	DTNA	dystrobrevin, alpha	19919	0.27
chr13_50649761_50650212	0.94	DLEU1	deleted in lymphocytic leukemia 1 (non-protein coding)	6321	0.18
chr8_57594130_57594603	0.90	RP11-17A4.2		192709	0.03
chr12_84188485_84188636	0.89	ENSG00000221148	.	388667	0.01
chr6_18749403_18749554	0.89	ENSG00000207775	.	177463	0.03
chr5_76979205_76979356	0.89	TBCA	tubulin folding cofactor A	31862	0.19
chr1_196622943_196623164	0.86	CFH	complement factor H	1867	0.41
chr1_197163991_197164285	0.86	ZBTB41	zinc finger and BTB domain containing 41	5534	0.22
chr12_109226312_109226796	0.85	ENSG00000207622	.	4228	0.18
chr16_87469465_87469755	0.85	ZCCHC14	zinc finger, CCHC domain containing 14	2870	0.22
chr3_98616545_98616732	0.85	DCBLD2	discoidin, CUB and LCCL domain containing 2	3377	0.22
chr2_33713796_33713947	0.83	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)	12155	0.26
chr6_132259983_132260134	0.83	RP11-69I8.3		12028	0.21
chr17_15602478_15603813	0.83	ZNF286A	Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.	54	0.96
chr4_177699520_177699725	0.82	VEGFC	vascular endothelial growth factor C	14259	0.29
chr14_36786542_36786693	0.81	MBIP	MAP3K12 binding inhibitory protein 1	2459	0.33
chr9_18477823_18478188	0.81	ADAMTSL1	ADAMTS-like 1	3774	0.35
chr7_134540301_134540539	0.81	CALD1	caldesmon 1	11172	0.29
chr1_221899701_221899890	0.81	DUSP10	dual specificity phosphatase 10	11007	0.31
chr12_46943504_46943655	0.80	SLC38A2	solute carrier family 38, member 2	176929	0.03
chr6_49806623_49806774	0.79	CRISP1	cysteine-rich secretory protein 1	18418	0.17
chr4_81193524_81193675	0.79	FGF5	fibroblast growth factor 5	5806	0.27
chr15_49718551_49718707	0.78	FGF7	fibroblast growth factor 7	3172	0.3
chr4_152146952_152147499	0.78	SH3D19	SH3 domain containing 19	7	0.98
chr3_106954974_106955246	0.77	ENSG00000220989	.	128919	0.06
chr10_90710175_90710354	0.76	ACTA2	actin, alpha 2, smooth muscle, aorta	2266	0.25
chr9_5454387_5454538	0.76	CD274	CD274 molecule	3937	0.24
chr12_47164577_47164728	0.75	SLC38A4	solute carrier family 38, member 4	1565	0.57
chr10_4814227_4814378	0.75	AKR1E2	aldo-keto reductase family 1, member E2	14519	0.27
chr8_13363407_13363558	0.74	DLC1	deleted in liver cancer 1	6732	0.24
chr3_16219029_16219297	0.74	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	2947	0.33
chr2_221111379_221111530	0.74	ENSG00000221199	.	54855	0.17
chr7_116144688_116144839	0.73	CAV2	caveolin 2	4929	0.17
chr4_81191052_81191243	0.73	FGF5	fibroblast growth factor 5	3354	0.31
chr18_2578553_2578704	0.73	NDC80	NDC80 kinetochore complex component	780	0.56
chr6_19840250_19840424	0.73	RP1-167F1.2		1026	0.58
chr9_75593600_75593751	0.72	ALDH1A1	aldehyde dehydrogenase 1 family, member A1	25703	0.27
chr2_46946334_46946485	0.72	SOCS5	suppressor of cytokine signaling 5	20083	0.19
chr1_33219625_33220407	0.72	KIAA1522	KIAA1522	394	0.82
chr18_40511173_40511637	0.72	RIT2	Ras-like without CAAX 2	184209	0.03
chr6_152237463_152237738	0.71	ESR1	estrogen receptor 1	35808	0.22
chr6_121756849_121757212	0.71	GJA1	gap junction protein, alpha 1, 43kDa	192	0.94
chr9_110053271_110053422	0.71	RAD23B	RAD23 homolog B (S. cerevisiae)	6370	0.31
chr11_118305386_118306890	0.70	RP11-770J1.4		217	0.83
chr8_22224818_22225894	0.70	SLC39A14	solute carrier family 39 (zinc transporter), member 14	305	0.9
chr12_68932399_68933004	0.70	RAP1B	RAP1B, member of RAS oncogene family	71918	0.11
chr15_49719079_49719362	0.70	FGF7	fibroblast growth factor 7	3763	0.28
chr14_29228686_29229081	0.70	RP11-966I7.1		5586	0.17
chr2_134136287_134136438	0.70	ENSG00000222068	.	12608	0.22
chr13_73438368_73438629	0.69	ENSG00000220981	.	13272	0.19
chr4_123751258_123751409	0.69	ENSG00000253069	.	3164	0.23
chr5_119935308_119935494	0.69	PRR16	proline rich 16	17382	0.29
chr2_1725848_1726016	0.69	PXDN	peroxidasin homolog (Drosophila)	22282	0.24
chr5_141509561_141509712	0.68	NDFIP1	Nedd4 family interacting protein 1	21566	0.22
chr9_20570402_20570553	0.68	ENSG00000252324	.	5739	0.24
chr6_150588789_150588940	0.68	ENSG00000201628	.	59035	0.12
chr2_53971623_53971774	0.68	GPR75-ASB3	GPR75-ASB3 readthrough	20988	0.16
chr11_86664088_86664372	0.68	FZD4	frizzled family receptor 4	2203	0.37
chr13_98630645_98630895	0.68	IPO5	importin 5	1354	0.57
chr4_114680367_114680518	0.68	CAMK2D	calcium/calmodulin-dependent protein kinase II delta	1782	0.52
chr15_99432888_99433039	0.68	IGF1R	insulin-like growth factor 1 receptor	607	0.75
chr4_87361949_87362100	0.67	MAPK10	mitogen-activated protein kinase 10	12259	0.27
chr4_43393406_43393557	0.67	ENSG00000239464	.	207373	0.03
chr2_38265076_38265999	0.67	RMDN2-AS1	RMDN2 antisense RNA 1	2053	0.33
chrX_108958062_108958213	0.67	ACSL4	acyl-CoA synthetase long-chain family member 4	18305	0.22
chr15_39186386_39186537	0.66	C15orf53	chromosome 15 open reading frame 53	197662	0.03
chr6_133908785_133908936	0.66	RP3-323P13.2		75994	0.11
chr1_28390431_28390759	0.65	EYA3	eyes absent homolog 3 (Drosophila)	5997	0.17
chr10_15138786_15140121	0.65	RPP38	ribonuclease P/MRP 38kDa subunit	34	0.62
chr2_216393577_216393859	0.65	AC012462.1		92742	0.08
chr16_86613931_86614082	0.65	FOXL1	forkhead box L1	1891	0.3
chr13_52917687_52917849	0.65	TPTE2P2	transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 pseudogene 2	45805	0.13
chr13_74705317_74705609	0.65	KLF12	Kruppel-like factor 12	2931	0.41
chrX_19013200_19013364	0.65	PHKA2	phosphorylase kinase, alpha 2 (liver)	10566	0.25
chr13_80705236_80705471	0.64	SPRY2	sprouty homolog 2 (Drosophila)	208441	0.03
chr8_110348245_110348396	0.64	NUDCD1	NudC domain containing 1	1706	0.29
chr1_179111271_179111703	0.64	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr2_165651274_165651425	0.64	COBLL1	cordon-bleu WH2 repeat protein-like 1	21085	0.19
chr4_13894276_13894602	0.64	ENSG00000252092	.	234188	0.02
chr4_71503427_71503612	0.64	ENAM	enamelin	9058	0.14
chr11_18329168_18329444	0.64	HPS5	Hermansky-Pudlak syndrome 5	11714	0.12
chr4_81200853_81201004	0.64	FGF5	fibroblast growth factor 5	13135	0.24
chr18_43633273_43633424	0.64	PSTPIP2	proline-serine-threonine phosphatase interacting protein 2	18875	0.14
chr15_56199751_56199985	0.63	NEDD4	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	7984	0.25
chr18_9923723_9923874	0.63	ENSG00000223138	.	119	0.96
chr1_163039219_163039545	0.63	RGS4	regulator of G-protein signaling 4	231	0.96
chr4_157890835_157890986	0.63	PDGFC	platelet derived growth factor C	1145	0.55
chr6_56405555_56405706	0.63	DST	dystonin	66842	0.13
chr2_38070591_38070742	0.63	RMDN2	regulator of microtubule dynamics 2	79664	0.1
chr9_91928267_91928614	0.62	ENSG00000265112	.	1300	0.38
chr5_35249380_35249572	0.62	PRLR	prolactin receptor	18682	0.27
chr1_94701176_94701460	0.62	ARHGAP29	Rho GTPase activating protein 29	1803	0.43
chr8_24011160_24011311	0.62	ENSG00000207201	.	76564	0.11
chr10_15411519_15412658	0.62	FAM171A1	family with sequence similarity 171, member A1	970	0.7
chr8_86350363_86351282	0.62	CA3	carbonic anhydrase III, muscle specific	234	0.93
chr18_61550376_61550527	0.62	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	4483	0.21
chr13_45146263_45146555	0.61	TSC22D1	TSC22 domain family, member 1	3983	0.32
chr1_98623173_98623324	0.61	ENSG00000225206	.	111521	0.07
chr4_116464375_116464526	0.61	NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	429418	0.01
chr4_157201330_157201481	0.61	ENSG00000221189	.	16393	0.3
chr14_100260565_100260825	0.60	EML1	echinoderm microtubule associated protein like 1	923	0.67
chr4_178167836_178167987	0.60	RP11-487E13.1	Uncharacterized protein	2016	0.4
chr5_139503395_139503546	0.60	IGIP	IgA-inducing protein	2051	0.25
chrX_47507821_47507972	0.60	ELK1	ELK1, member of ETS oncogene family	1991	0.22
chr2_145235570_145235759	0.60	ZEB2	zinc finger E-box binding homeobox 2	39451	0.18
chr2_81994863_81995014	0.60	ENSG00000242118	.	199265	0.03
chr7_81794457_81794608	0.59	ENSG00000221262	.	124861	0.06
chr12_91504813_91504964	0.59	LUM	lumican	720	0.73
chr1_218672576_218672996	0.59	C1orf143	chromosome 1 open reading frame 143	10652	0.26
chr8_26152105_26152449	0.59	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	1278	0.57
chr6_119666759_119666910	0.59	MAN1A1	mannosidase, alpha, class 1A, member 1	4067	0.29
chr8_65753978_65754352	0.59	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	42847	0.2
chr1_32268297_32268720	0.59	SPOCD1	SPOC domain containing 1	4068	0.18
chr1_196527542_196527719	0.59	ENSG00000265986	.	23981	0.22
chr13_51804353_51804504	0.59	FAM124A	family with sequence similarity 124A	7921	0.25
chr3_132316198_132316509	0.59	ACKR4	atypical chemokine receptor 4	272	0.93
chr2_230035602_230035855	0.59	PID1	phosphotyrosine interaction domain containing 1	61073	0.14
chr11_121968562_121968780	0.59	ENSG00000207971	.	1881	0.27
chr2_199237110_199237329	0.58	ENSG00000252511	.	194234	0.03
chr6_136359997_136360148	0.58	RP13-143G15.3		25704	0.21
chr18_60386318_60386600	0.58	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	3776	0.25
chr5_78858614_78858786	0.58	ENSG00000207391	.	28024	0.18
chr6_119066068_119066219	0.58	CEP85L	centrosomal protein 85kDa-like	34905	0.21
chr1_86020967_86021218	0.58	DDAH1	dimethylarginine dimethylaminohydrolase 1	22841	0.17
chr17_67056652_67056803	0.58	ABCA9	ATP-binding cassette, sub-family A (ABC1), member 9	320	0.9
chr13_52212841_52213032	0.58	ENSG00000242893	.	44585	0.11
chr6_79315199_79315473	0.57	IRAK1BP1	interleukin-1 receptor-associated kinase 1 binding protein 1	261853	0.02
chr4_160170135_160170337	0.57	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	17797	0.23
chr7_18549207_18549425	0.57	HDAC9	histone deacetylase 9	380	0.92
chr12_109104590_109104741	0.57	CORO1C	coronin, actin binding protein, 1C	7814	0.16
chr12_50665639_50665877	0.57	LIMA1	LIM domain and actin binding 1	11509	0.13
chr12_88812261_88812515	0.57	ENSG00000199245	.	11831	0.3
chr9_74429580_74429731	0.57	TMEM2	transmembrane protein 2	1951	0.44
chr18_20805843_20806036	0.57	RP11-17J14.2		34379	0.18
chr3_11679126_11679277	0.57	VGLL4	vestigial like 4 (Drosophila)	6197	0.23
chr7_35870864_35871015	0.57	SEPT7	septin 7	761	0.7
chr13_34217183_34217463	0.57	RFC3	replication factor C (activator 1) 3, 38kDa	174863	0.03
chr6_85468375_85468673	0.57	TBX18	T-box 18	4549	0.33
chr1_85664852_85665003	0.57	SYDE2	synapse defective 1, Rho GTPase, homolog 2 (C. elegans)	1802	0.33
chr2_183901778_183902686	0.57	NCKAP1	NCK-associated protein 1	968	0.52
chr17_18584865_18586095	0.57	ZNF286B	zinc finger protein 286B	61	0.96
chr8_124775567_124775718	0.57	FAM91A1	family with sequence similarity 91, member A1	5054	0.24
chr8_119963118_119963285	0.56	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	1238	0.55
chr9_21507089_21507410	0.56	ENSG00000199177	.	4935	0.17
chr8_98102647_98102881	0.56	KB-1958F4.2		42843	0.16
chr2_179728284_179728567	0.56	CCDC141	coiled-coil domain containing 141	21253	0.16
chr21_26701536_26701687	0.56	ENSG00000238660	.	9708	0.29
chr3_29377379_29377667	0.56	ENSG00000216169	.	33389	0.18
chr6_25003002_25003351	0.56	ENSG00000244618	.	28334	0.16
chrX_101054612_101054832	0.56	NXF5	nuclear RNA export factor 5	43449	0.14
chr18_53735331_53735482	0.56	ENSG00000201816	.	11419	0.32
chr18_55475327_55475478	0.56	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	5075	0.26
chr17_40671414_40671565	0.56	ENSG00000265611	.	5283	0.09
chr5_72746721_72747193	0.56	FOXD1	forkhead box D1	2605	0.29
chr4_141176965_141177116	0.55	SCOC	short coiled-coil protein	1400	0.47
chr1_59859347_59859498	0.55	FGGY	FGGY carbohydrate kinase domain containing	83663	0.11
chr7_78398482_78399243	0.55	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	1534	0.56
chr6_8433732_8434221	0.55	SLC35B3	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3	1740	0.54
chr1_202549948_202550099	0.55	RP11-569A11.1		23373	0.18
chr3_12277414_12277664	0.55	PPARG	peroxisome proliferator-activated receptor gamma	51328	0.15
chr13_69794038_69794189	0.55	ENSG00000243671	.	525900	0.0
chr9_22007341_22007594	0.55	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	1485	0.34
chr20_4910718_4910869	0.55	SLC23A2	solute carrier family 23 (ascorbic acid transporter), member 2	30500	0.16
chr1_183841636_183841838	0.54	RGL1	ral guanine nucleotide dissociation stimulator-like 1	67447	0.11
chr19_46970109_46970502	0.54	PNMAL1	paraneoplastic Ma antigen family-like 1	4359	0.16
chr7_19150955_19151106	0.54	AC003986.6		1067	0.46
chr7_84120799_84120950	0.54	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	991	0.72
chr2_203881741_203882170	0.54	NBEAL1	neurobeachin-like 1	2353	0.35
chr17_61106096_61106247	0.54	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	19250	0.23
chr8_29028850_29029034	0.54	ENSG00000264328	.	28732	0.15
chr2_216299376_216299642	0.54	FN1	fibronectin 1	1281	0.4
chr12_15837748_15837899	0.54	ENSG00000200105	.	13079	0.23
chr1_193378431_193378582	0.54	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	222722	0.02
chr6_73360318_73360481	0.54	KCNQ5-IT1	KCNQ5 intronic transcript 1 (non-protein coding)	20176	0.23
chr2_189840264_189840425	0.54	COL3A1	collagen, type III, alpha 1	1245	0.47
chr5_127870654_127870805	0.54	FBN2	fibrillin 2	2785	0.29
chr6_154781546_154781697	0.54	CNKSR3	CNKSR family member 3	18004	0.28
chr14_89315681_89315832	0.54	TTC8	tetratricopeptide repeat domain 8	7884	0.19
chr21_38731087_38731365	0.54	AP001437.1		7008	0.21
chr4_39523474_39523669	0.54	UGDH	UDP-glucose 6-dehydrogenase	4606	0.18
chr21_36256046_36256553	0.54	RUNX1	runt-related transcription factor 1	3181	0.38
chrX_17431119_17431354	0.53	ENSG00000265465	.	12768	0.22
chr13_74606153_74606483	0.53	KLF12	Kruppel-like factor 12	37132	0.24
chr21_18824129_18824280	0.53	ENSG00000252613	.	795	0.6
chr2_216288358_216288696	0.53	FN1	fibronectin 1	12263	0.21
chr3_105663549_105663788	0.53	CBLB	Cbl proto-oncogene B, E3 ubiquitin protein ligase	75272	0.13
chr10_15721874_15722025	0.53	ITGA8	integrin, alpha 8	40175	0.21
chr14_25580105_25580256	0.53	STXBP6	syntaxin binding protein 6 (amisyn)	60677	0.16
chr12_13351605_13351756	0.53	EMP1	epithelial membrane protein 1	1960	0.42

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.5	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	0.3	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.3	1.4	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.3	0.6	GO:0060594	mammary gland specification(GO:0060594)
0.3	0.8	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.3	1.6	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.3	1.6	GO:0016264	gap junction assembly(GO:0016264)
0.2	0.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.0	GO:0043589	skin morphogenesis(GO:0043589)
0.2	0.7	GO:0071692	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.9	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.2	0.9	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.2	1.6	GO:0043206	extracellular fibril organization(GO:0043206) fibril organization(GO:0097435)
0.2	0.7	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.2	0.2	GO:0032650	regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.2	0.4	GO:0060996	dendritic spine development(GO:0060996)
0.2	1.0	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2	0.6	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.2	0.5	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.2	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.2	0.7	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.2	0.3	GO:0060463	lung lobe development(GO:0060462) lung lobe morphogenesis(GO:0060463)
0.2	0.2	GO:0060242	contact inhibition(GO:0060242)
0.2	0.9	GO:0002634	regulation of germinal center formation(GO:0002634)
0.2	0.5	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.7	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.1	0.4	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.3	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.4	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	0.6	GO:0006533	aspartate metabolic process(GO:0006531) aspartate catabolic process(GO:0006533)
0.1	0.4	GO:0016576	histone dephosphorylation(GO:0016576)
0.1	0.5	GO:0008218	bioluminescence(GO:0008218)
0.1	0.5	GO:0010107	potassium ion import(GO:0010107)
0.1	0.5	GO:0072268	pattern specification involved in metanephros development(GO:0072268)
0.1	0.2	GO:0010715	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.1	0.4	GO:0072677	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.1	0.4	GO:0007132	meiotic metaphase I(GO:0007132)
0.1	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.7	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.3	GO:0051580	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.1	0.3	GO:0051014	actin filament severing(GO:0051014)
0.1	0.6	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.2	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.2	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.9	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.8	GO:0090399	replicative senescence(GO:0090399)
0.1	0.3	GO:0047484	regulation of response to osmotic stress(GO:0047484)
0.1	1.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.3	GO:0008049	male courtship behavior(GO:0008049)
0.1	0.4	GO:0060753	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1	0.5	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.1	0.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
0.1	1.6	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.1	0.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.1	0.1	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	1.9	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.3	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.2	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.1	0.1	GO:0002890	negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.1	0.1	GO:0042637	catagen(GO:0042637)
0.1	0.6	GO:0030146	obsolete diuresis(GO:0030146)
0.1	0.3	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.1	GO:1901798	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	0.3	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.3	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.2	GO:0090036	regulation of protein kinase C signaling(GO:0090036) positive regulation of protein kinase C signaling(GO:0090037)
0.1	0.1	GO:0060433	bronchus development(GO:0060433)
0.1	0.2	GO:0010665	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.2	GO:0035095	behavioral response to nicotine(GO:0035095)
0.1	0.3	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.1	0.3	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.3	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.1	0.3	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.3	GO:0060023	soft palate development(GO:0060023)
0.1	0.2	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.3	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.2	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.4	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.1	0.2	GO:0048840	otolith development(GO:0048840)
0.1	0.5	GO:0044091	membrane biogenesis(GO:0044091)
0.1	0.5	GO:0046851	negative regulation of tissue remodeling(GO:0034104) negative regulation of bone resorption(GO:0045779) negative regulation of bone remodeling(GO:0046851)
0.1	0.2	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.6	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.4	GO:0060037	pharyngeal system development(GO:0060037)
0.1	0.8	GO:0006949	syncytium formation(GO:0006949)
0.1	0.2	GO:0060013	righting reflex(GO:0060013)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.3	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1	0.1	GO:0032224	positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.1	0.2	GO:0014889	muscle atrophy(GO:0014889)
0.1	0.4	GO:0071305	cellular response to vitamin D(GO:0071305)
0.1	0.7	GO:0007567	parturition(GO:0007567)
0.1	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.1	0.2	GO:0048935	peripheral nervous system neuron development(GO:0048935)
0.1	0.3	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.1	0.3	GO:0051967	negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1	0.1	GO:0014819	regulation of skeletal muscle contraction(GO:0014819)
0.1	0.2	GO:0048539	bone marrow development(GO:0048539)
0.1	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0046475	phosphatidylcholine catabolic process(GO:0034638) glycerophospholipid catabolic process(GO:0046475)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.9	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.1	0.3	GO:0050667	homocysteine metabolic process(GO:0050667)
0.1	0.3	GO:0015889	cobalamin transport(GO:0015889)
0.1	0.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.1	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.1	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1	0.2	GO:0002042	cell migration involved in sprouting angiogenesis(GO:0002042)
0.1	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.1	0.4	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.2	GO:0033197	response to vitamin E(GO:0033197)
0.1	0.2	GO:0010842	retina layer formation(GO:0010842)
0.1	0.4	GO:0043113	receptor clustering(GO:0043113)
0.1	1.4	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.1	GO:0032693	negative regulation of interleukin-10 production(GO:0032693)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	1.0	GO:0045103	intermediate filament-based process(GO:0045103)
0.1	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.1	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.1	0.3	GO:0002076	osteoblast development(GO:0002076)
0.1	0.2	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.1	1.0	GO:0035136	forelimb morphogenesis(GO:0035136)
0.1	0.3	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.1	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.2	GO:0007386	compartment pattern specification(GO:0007386)
0.1	0.2	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1	0.1	GO:0034393	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.4	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0021570	rhombomere 4 development(GO:0021570)
0.1	0.2	GO:0033025	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	0.1	GO:0060438	trachea development(GO:0060438)
0.1	0.3	GO:0006857	oligopeptide transport(GO:0006857)
0.1	0.5	GO:0070875	positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.1	0.2	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.0	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) myosin filament assembly(GO:0031034) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.0	GO:0072177	mesonephric duct development(GO:0072177) nephric duct morphogenesis(GO:0072178)
0.0	0.2	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.0	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.1	GO:0060677	ureteric bud elongation(GO:0060677)
0.0	0.1	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.1	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0060841	venous blood vessel morphogenesis(GO:0048845) venous blood vessel development(GO:0060841)
0.0	0.2	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.3	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0002855	natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0019049	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.3	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.2	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.3	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.2	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.2	GO:2000258	negative regulation of humoral immune response(GO:0002921) negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609) protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.4	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.1	GO:1903332	regulation of protein folding(GO:1903332)
0.0	0.1	GO:0010939	regulation of necrotic cell death(GO:0010939)
0.0	0.4	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.2	GO:0048520	positive regulation of behavior(GO:0048520)
0.0	0.1	GO:0051197	positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of nucleoside metabolic process(GO:0045979) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) positive regulation of ATP metabolic process(GO:1903580)
0.0	0.0	GO:0061217	regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.4	GO:0050806	positive regulation of synaptic transmission(GO:0050806)
0.0	0.1	GO:0061726	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119)
0.0	0.1	GO:0022601	menstrual cycle phase(GO:0022601)
0.0	0.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.6	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0045007	depurination(GO:0045007)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.8	GO:0006730	one-carbon metabolic process(GO:0006730)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:1901655	cellular response to ketone(GO:1901655)
0.0	0.2	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.4	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.7	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0003160	endocardium development(GO:0003157) endocardium morphogenesis(GO:0003160)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.2	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:2000644	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0030240	skeletal myofibril assembly(GO:0014866) skeletal muscle thin filament assembly(GO:0030240)
0.0	0.1	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0072239	metanephric glomerulus development(GO:0072224) metanephric glomerulus vasculature development(GO:0072239)
0.0	0.1	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0019236	response to pheromone(GO:0019236)
0.0	0.1	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.5	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0072172	mesonephric tubule formation(GO:0072172)
0.0	0.2	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0006726	eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	3.1	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.3	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0042517	positive regulation of tyrosine phosphorylation of Stat3 protein(GO:0042517)
0.0	0.1	GO:0010633	negative regulation of epithelial cell migration(GO:0010633)
0.0	0.4	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0003352	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.0	GO:0061029	eyelid development in camera-type eye(GO:0061029)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0060602	branch elongation of an epithelium(GO:0060602)
0.0	0.1	GO:0014033	neural crest cell differentiation(GO:0014033)
0.0	0.1	GO:0010042	response to manganese ion(GO:0010042)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0009822	alkaloid catabolic process(GO:0009822)
0.0	0.1	GO:0007530	sex determination(GO:0007530)
0.0	0.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.2	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.1	GO:0000019	regulation of mitotic recombination(GO:0000019)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.0	GO:0055022	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0	0.1	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.3	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.0	GO:0070254	mucus secretion(GO:0070254)
0.0	0.0	GO:0021542	dentate gyrus development(GO:0021542)
0.0	0.8	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.1	GO:0007350	blastoderm segmentation(GO:0007350)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.0	0.0	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.3	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.0	GO:0021795	cerebral cortex cell migration(GO:0021795)
0.0	0.2	GO:0007141	male meiosis I(GO:0007141)
0.0	0.0	GO:1903726	negative regulation of phospholipid biosynthetic process(GO:0071072) negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.2	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0090398	cellular senescence(GO:0090398)
0.0	0.1	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0045581	negative regulation of T cell differentiation(GO:0045581) negative regulation of lymphocyte differentiation(GO:0045620)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838) carnitine transport(GO:0015879)
0.0	0.1	GO:0060045	positive regulation of cardiac muscle tissue growth(GO:0055023) positive regulation of cardiac muscle tissue development(GO:0055025) positive regulation of cardiac muscle cell proliferation(GO:0060045)
0.0	0.0	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.0	GO:0019336	phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0046541	saliva secretion(GO:0046541)
0.0	0.2	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.0	GO:0051877	pigment granule aggregation in cell center(GO:0051877)
0.0	0.1	GO:0043114	regulation of vascular permeability(GO:0043114)
0.0	0.0	GO:0015870	acetylcholine transport(GO:0015870) acetate ester transport(GO:1901374)
0.0	0.0	GO:0033079	immature T cell proliferation(GO:0033079)
0.0	0.0	GO:0061384	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0	0.1	GO:0045663	positive regulation of myoblast differentiation(GO:0045663)
0.0	0.1	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237) positive regulation of calcium ion transmembrane transporter activity(GO:1901021) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.0	GO:0043536	positive regulation of blood vessel endothelial cell migration(GO:0043536)
0.0	0.0	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.0	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.0	GO:0045661	regulation of myoblast differentiation(GO:0045661)
0.0	0.2	GO:0042130	negative regulation of T cell proliferation(GO:0042130)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.1	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0032456	endocytic recycling(GO:0032456)
0.0	0.3	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0003407	neural retina development(GO:0003407)
0.0	0.0	GO:0055075	potassium ion homeostasis(GO:0055075)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.0	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0034371	chylomicron remodeling(GO:0034371)
0.0	0.1	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.0	GO:2001234	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:0044803	multi-organism membrane organization(GO:0044803)
0.0	0.1	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.2	GO:0031532	actin cytoskeleton reorganization(GO:0031532)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.1	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.0	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.1	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.0	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0002069	columnar/cuboidal epithelial cell maturation(GO:0002069)
0.0	0.0	GO:0048148	behavioral response to cocaine(GO:0048148)
0.0	0.1	GO:0009070	serine family amino acid biosynthetic process(GO:0009070)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:0019731	antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0006999	nuclear pore organization(GO:0006999)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.0	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285) depyrimidination(GO:0045008)
0.0	0.0	GO:0015697	quaternary ammonium group transport(GO:0015697)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0071482	cellular response to light stimulus(GO:0071482)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0042461	photoreceptor cell development(GO:0042461)
0.0	0.1	GO:0032228	regulation of synaptic transmission, GABAergic(GO:0032228)
0.0	0.0	GO:0071801	regulation of podosome assembly(GO:0071801) positive regulation of podosome assembly(GO:0071803)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0032891	negative regulation of organic acid transport(GO:0032891) negative regulation of amino acid transport(GO:0051956)
0.0	0.0	GO:0071267	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.0	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0	0.0	GO:0042135	neurotransmitter catabolic process(GO:0042135)
0.0	0.0	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0021895	cerebral cortex neuron differentiation(GO:0021895)
0.0	0.1	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.0	GO:0031054	pre-miRNA processing(GO:0031054)
0.0	0.1	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.0	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0019755	one-carbon compound transport(GO:0019755)
0.0	0.1	GO:0006544	glycine metabolic process(GO:0006544) glycine catabolic process(GO:0006546)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.0	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.0	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.0	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.0	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.0	GO:1901419	regulation of response to alcohol(GO:1901419)
0.0	0.0	GO:0090322	regulation of superoxide metabolic process(GO:0090322)
0.0	0.0	GO:0071043	CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.0	GO:0032786	positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.0	0.0	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.3	3.7	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	1.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	1.1	GO:0005915	zonula adherens(GO:0005915)
0.2	0.5	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	1.1	GO:0005916	fascia adherens(GO:0005916)
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.1	GO:0030118	clathrin coat(GO:0030118)
0.1	0.5	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.4	GO:0032591	dendritic spine membrane(GO:0032591)
0.1	0.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.8	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	0.3	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.4	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0042587	glycogen granule(GO:0042587)
0.1	0.5	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.1	0.5	GO:0001527	microfibril(GO:0001527)
0.1	0.2	GO:0071438	invadopodium membrane(GO:0071438)
0.1	0.3	GO:0043218	compact myelin(GO:0043218)
0.1	0.2	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.1	0.2	GO:0071942	XPC complex(GO:0071942)
0.1	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.3	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.3	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.1	0.1	GO:0071437	invadopodium(GO:0071437)
0.1	0.4	GO:0005655	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.1	0.2	GO:0000124	SAGA complex(GO:0000124)
0.1	0.7	GO:0005581	collagen trimer(GO:0005581)
0.1	0.3	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.1	0.2	GO:0005827	polar microtubule(GO:0005827)
0.1	0.2	GO:0032059	bleb(GO:0032059)
0.1	0.2	GO:0043260	laminin-11 complex(GO:0043260)
0.0	0.3	GO:0043256	laminin complex(GO:0043256)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.9	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	1.3	GO:0034704	calcium channel complex(GO:0034704)
0.0	2.2	GO:0044853	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0	1.3	GO:0030018	Z disc(GO:0030018)
0.0	0.2	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.2	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0033643	host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.5	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.2	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.3	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.0	7.8	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0030673	axolemma(GO:0030673)
0.0	0.2	GO:0031512	motile primary cilium(GO:0031512)
0.0	2.1	GO:0030027	lamellipodium(GO:0030027)
0.0	1.8	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.4	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0060076	excitatory synapse(GO:0060076)
0.0	0.7	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.5	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.5	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0031105	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.4	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	1.6	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0032982	myosin filament(GO:0032982)
0.0	0.0	GO:0045334	clathrin-coated endocytic vesicle(GO:0045334)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0005639	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.6	GO:0030426	growth cone(GO:0030426)
0.0	0.7	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.7	GO:0030016	myofibril(GO:0030016)
0.0	0.0	GO:0042272	nuclear RNA export factor complex(GO:0042272)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.0	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.0	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.0	GO:0033150	cytoskeletal calyx(GO:0033150)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0001159	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.3	1.1	GO:0045499	chemorepellent activity(GO:0045499)
0.3	1.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2	0.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	2.5	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.2	0.6	GO:0016151	nickel cation binding(GO:0016151)
0.2	0.6	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	1.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.2	0.7	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	1.1	GO:0017166	vinculin binding(GO:0017166)
0.2	0.5	GO:0002162	dystroglycan binding(GO:0002162)
0.2	1.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.2	0.8	GO:0042805	actinin binding(GO:0042805)
0.2	1.2	GO:0030332	cyclin binding(GO:0030332)
0.1	1.6	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.4	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.1	0.8	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.1	0.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	1.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	0.4	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.1	0.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.3	GO:0097493	extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1	1.1	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.5	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	0.3	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.6	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.2	GO:0045118	azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.1	1.0	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.2	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.1	0.5	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.4	GO:0030507	spectrin binding(GO:0030507)
0.1	0.4	GO:0004046	aminoacylase activity(GO:0004046)
0.1	0.2	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.1	0.3	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.1	0.3	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.6	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.1	GO:0043559	insulin binding(GO:0043559)
0.1	4.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.3	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.1	0.2	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.9	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.4	GO:0005521	lamin binding(GO:0005521)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.2	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0003696	satellite DNA binding(GO:0003696)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.1	0.2	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	1.2	GO:0050840	extracellular matrix binding(GO:0050840)
0.1	0.2	GO:0031545	procollagen-proline 4-dioxygenase activity(GO:0004656) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.5	GO:0030544	Hsp70 protein binding(GO:0030544)
0.1	0.4	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1	1.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.1	0.3	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.5	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	0.6	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.6	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.4	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.5	GO:0030553	cGMP binding(GO:0030553)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.2	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.4	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.4	GO:0004526	ribonuclease P activity(GO:0004526)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.9	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.3	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.4	GO:0019104	DNA N-glycosylase activity(GO:0019104)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.2	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.5	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.2	GO:0004716	receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.1	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.0	0.3	GO:0070717	poly-purine tract binding(GO:0070717)
0.0	0.1	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.4	GO:0005003	ephrin receptor activity(GO:0005003)
0.0	0.1	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0016503	pheromone receptor activity(GO:0016503)
0.0	0.0	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.3	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0051378	serotonin binding(GO:0051378)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0	0.4	GO:0008395	steroid hydroxylase activity(GO:0008395)
0.0	0.0	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.1	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.0	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.4	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004461	lactose synthase activity(GO:0004461)
0.0	0.1	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0015168	glycerol transmembrane transporter activity(GO:0015168)
0.0	1.0	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0044390	ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0	0.1	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.2	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.3	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0030276	clathrin binding(GO:0030276)
0.0	0.2	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.2	GO:0045296	cadherin binding(GO:0045296)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.0	GO:0031705	bombesin receptor binding(GO:0031705) endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.0	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.0	GO:0034648	histone demethylase activity (H3-K4 specific)(GO:0032453) histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.5	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.0	GO:0004556	alpha-amylase activity(GO:0004556) amylase activity(GO:0016160)
0.0	1.1	GO:0003704	obsolete specific RNA polymerase II transcription factor activity(GO:0003704)
0.0	0.1	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.7	GO:0005262	calcium channel activity(GO:0005262)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.2	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.1	GO:0004745	retinol dehydrogenase activity(GO:0004745)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.0	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.0	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.0	GO:0046848	hydroxyapatite binding(GO:0046848)
0.0	0.0	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.0	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.2	GO:0005272	sodium channel activity(GO:0005272)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0004977	melanocortin receptor activity(GO:0004977)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	5.1	NABA COLLAGENS	Genes encoding collagen proteins
0.1	1.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.0	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	1.7	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.1	0.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	1.8	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.6	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.1	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.0	1.9	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	1.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	1.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.3	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.9	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	1.0	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.7	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	3.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.5	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.4	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.0	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.0	ST GAQ PATHWAY	G alpha q Pathway
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.4	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.0	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.0	0.1	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.0	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.1	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.2	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.0	0.2	PID FGF PATHWAY	FGF signaling pathway
0.0	3.1	NABA SECRETED FACTORS	Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	0.4	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.2	1.8	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	1.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	4.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.4	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.1	4.1	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.1	1.3	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.1	1.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1	1.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.1	1.1	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	0.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.6	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.5	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	1.1	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	1.4	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	1.6	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.5	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.7	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.1	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.8	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.5	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.2	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.3	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.6	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.8	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.5	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME PI 3K CASCADE	Genes involved in PI-3K cascade
0.0	0.6	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.0	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.1	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.2	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.0	0.2	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.2	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.0	REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR	Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0	0.3	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.1	REACTOME TRAFFICKING OF AMPA RECEPTORS	Genes involved in Trafficking of AMPA receptors
0.0	0.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.0	0.1	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.0	0.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.1	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2

Results for IRX3

Z-value: 2.33

Motif logo

Transcription factors associated with IRX3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the IRX3 motif across conditions

Conditions sorted by the z-value of the IRX3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of IRX3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: