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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for ISL1

Z-value: 2.81

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Transcription factors associated with ISL1

Gene Symbol	Gene ID	Gene Info
ISL1 Ensembl NCBI GeneCards UniProt	ENSG00000016082.10	ISL LIM homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr5_50681604_50681755	ISL1	2173	0.315926	-0.62	7.4e-02	Click!
chr5_50680549_50680700	ISL1	1118	0.446872	-0.55	1.2e-01	Click!
chr5_50677388_50677864	ISL1	1295	0.402061	0.49	1.8e-01	Click!
chr5_50682748_50683080	ISL1	3408	0.266248	0.36	3.3e-01	Click!
chr5_50791420_50791583	ISL1	111995	0.066976	0.34	3.7e-01	Click!

Activity of the ISL1 motif across conditions

Conditions sorted by the z-value of the ISL1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_119963636_119964312	0.84	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	465	0.86
chr8_126013201_126013598	0.81	SQLE	squalene epoxidase	2613	0.23
chr21_17567832_17567983	0.79	ENSG00000201025	.	89182	0.1
chr13_33858654_33859881	0.71	STARD13	StAR-related lipid transfer (START) domain containing 13	625	0.76
chr14_100345979_100346191	0.71	EML1	echinoderm microtubule associated protein like 1	14139	0.22
chr6_131290698_131290904	0.71	EPB41L2	erythrocyte membrane protein band 4.1-like 2	822	0.76
chr2_106013989_106014195	0.71	FHL2	four and a half LIM domains 2	678	0.71
chr22_17679684_17679946	0.66	CECR1	cat eye syndrome chromosome region, candidate 1	858	0.6
chr7_94026391_94026542	0.65	COL1A2	collagen, type I, alpha 2	2593	0.39
chr19_56332953_56333104	0.62	NLRP11	NLR family, pyrin domain containing 11	3425	0.16
chr9_708078_708584	0.62	KANK1	KN motif and ankyrin repeat domains 1	1442	0.47
chr22_36233928_36234199	0.61	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	2202	0.43
chr1_172109224_172109375	0.61	ENSG00000207949	.	1252	0.44
chr3_87036535_87037613	0.61	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr1_99126586_99127126	0.59	SNX7	sorting nexin 7	380	0.93
chr17_32582682_32583141	0.59	AC005549.3	Uncharacterized protein	605	0.41
chr7_134464463_134465343	0.59	CALD1	caldesmon 1	474	0.89
chr6_121760674_121760877	0.58	GJA1	gap junction protein, alpha 1, 43kDa	3937	0.22
chr13_38171261_38171555	0.56	POSTN	periostin, osteoblast specific factor	1455	0.59
chr12_68915355_68915540	0.56	RAP1B	RAP1B, member of RAS oncogene family	89172	0.08
chr2_65593026_65593803	0.54	SPRED2	sprouty-related, EVH1 domain containing 2	370	0.89
chr1_170637207_170637377	0.54	PRRX1	paired related homeobox 1	4214	0.33
chr10_60234895_60235101	0.53	BICC1	bicaudal C homolog 1 (Drosophila)	37902	0.2
chr13_36047635_36048256	0.53	MAB21L1	mab-21-like 1 (C. elegans)	2887	0.26
chr16_55513844_55514378	0.53	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	201	0.95
chr7_18549207_18549425	0.52	HDAC9	histone deacetylase 9	380	0.92
chr6_112619462_112619866	0.52	LAMA4	laminin, alpha 4	43523	0.13
chr20_34024292_34024443	0.52	GDF5	growth differentiation factor 5	1656	0.23
chr12_78334931_78335200	0.51	NAV3	neuron navigator 3	24991	0.28
chr8_93115764_93116215	0.51	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	475	0.9
chr2_189844043_189844303	0.51	ENSG00000221502	.	1355	0.48
chr14_29859562_29859789	0.51	ENSG00000257522	.	11813	0.29
chr3_64252728_64253099	0.51	PRICKLE2	prickle homolog 2 (Drosophila)	742	0.75
chr21_17790454_17790609	0.50	ENSG00000207638	.	120878	0.06
chrX_48335474_48335776	0.50	FTSJ1	FtsJ RNA methyltransferase homolog 1 (E. coli)	755	0.51
chr2_175710954_175711206	0.49	CHN1	chimerin 1	53	0.98
chr4_157890038_157890662	0.48	PDGFC	platelet derived growth factor C	1705	0.41
chr15_38545953_38546360	0.48	SPRED1	sprouty-related, EVH1 domain containing 1	774	0.79
chr6_121761121_121761295	0.48	GJA1	gap junction protein, alpha 1, 43kDa	4370	0.21
chr9_130615331_130615482	0.47	ENG	endoglin	1509	0.19
chr3_55512024_55512219	0.47	WNT5A	wingless-type MMTV integration site family, member 5A	3103	0.32
chr4_186853517_186853755	0.47	ENSG00000239034	.	13601	0.21
chr4_114068666_114068817	0.47	ANK2	ankyrin 2, neuronal	1953	0.44
chr20_50177465_50177621	0.46	NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	1625	0.52
chr3_23960351_23960502	0.46	RPL15	ribosomal protein L15	1230	0.41
chr18_53665373_53665862	0.46	ENSG00000201816	.	81208	0.12
chr2_33822936_33823087	0.46	FAM98A	family with sequence similarity 98, member A	1333	0.53
chr10_5490759_5491049	0.46	NET1	neuroepithelial cell transforming 1	2330	0.27
chr2_198024587_198024771	0.46	ANKRD44	ankyrin repeat domain 44	12051	0.23
chr2_27301899_27302732	0.46	EMILIN1	elastin microfibril interfacer 1	880	0.32
chr3_178684614_178685138	0.46	ZMAT3	zinc finger, matrin-type 3	104478	0.06
chr10_25009320_25009701	0.46	ARHGAP21	Rho GTPase activating protein 21	1285	0.59
chr9_91607704_91607855	0.45	S1PR3	sphingosine-1-phosphate receptor 3	1417	0.39
chr2_177501805_177501995	0.45	ENSG00000252027	.	27504	0.25
chr12_42982431_42982690	0.45	PRICKLE1	prickle homolog 1 (Drosophila)	918	0.69
chr7_130595370_130595521	0.45	ENSG00000226380	.	33147	0.2
chr3_114168204_114168554	0.45	ZBTB20	zinc finger and BTB domain containing 20	5151	0.29
chr1_177953163_177953341	0.45	SEC16B	SEC16 homolog B (S. cerevisiae)	13904	0.3
chr4_99468545_99468696	0.45	RP11-724M22.1		51105	0.16
chr2_144697505_144697690	0.45	AC016910.1		2957	0.34
chr3_159483781_159484285	0.45	IQCJ-SCHIP1	IQCJ-SCHIP1 readthrough	1141	0.44
chr17_46674371_46674522	0.45	HOXB-AS3	HOXB cluster antisense RNA 3	645	0.43
chr2_201473941_201474433	0.45	AOX1	aldehyde oxidase 1	21290	0.2
chr3_55162466_55162710	0.45	LRTM1	leucine-rich repeats and transmembrane domains 1	161473	0.04
chr3_112354153_112354320	0.45	CCDC80	coiled-coil domain containing 80	2708	0.34
chr6_131363438_131363589	0.44	EPB41L2	erythrocyte membrane protein band 4.1-like 2	20203	0.27
chr2_8817438_8817691	0.44	AC011747.7		900	0.54
chr6_112572588_112572957	0.44	LAMA4	laminin, alpha 4	2915	0.26
chr1_65005729_65006114	0.44	ENSG00000264470	.	39609	0.19
chr1_39572596_39572941	0.43	MACF1	microtubule-actin crosslinking factor 1	1685	0.35
chr14_63672530_63672681	0.43	RHOJ	ras homolog family member J	1028	0.62
chr12_56916774_56917003	0.43	RBMS2	RNA binding motif, single stranded interacting protein 2	1105	0.41
chr14_45711437_45711895	0.43	MIS18BP1	MIS18 binding protein 1	10714	0.2
chr19_46970109_46970502	0.43	PNMAL1	paraneoplastic Ma antigen family-like 1	4359	0.16
chr17_63693222_63693493	0.43	CEP112	centrosomal protein 112kDa	53485	0.17
chr22_41250473_41250953	0.43	ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	111	0.94
chr2_158113918_158114875	0.43	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	286	0.93
chr2_225847651_225847803	0.43	ENSG00000263828	.	27530	0.22
chr1_162603392_162603656	0.42	DDR2	discoidin domain receptor tyrosine kinase 2	1264	0.48
chr21_35133624_35133954	0.42	ITSN1	intersectin 1 (SH3 domain protein)	26443	0.2
chr7_137367241_137367406	0.42	DGKI	diacylglycerol kinase, iota	163959	0.04
chr9_18476160_18476529	0.42	ADAMTSL1	ADAMTS-like 1	2113	0.45
chr6_153489040_153489245	0.42	ENSG00000201939	.	8662	0.22
chr4_114897314_114897610	0.42	ARSJ	arylsulfatase family, member J	2690	0.37
chr15_77360412_77360563	0.42	RP11-797A18.6		180	0.94
chr6_132721877_132722093	0.42	MOXD1	monooxygenase, DBH-like 1	629	0.81
chr19_39149984_39150227	0.42	ACTN4	actinin, alpha 4	11727	0.12
chr6_85823864_85824548	0.42	NT5E	5'-nucleotidase, ecto (CD73)	335603	0.01
chr10_94958545_94959442	0.41	CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	125346	0.05
chr11_57545200_57545645	0.41	CTNND1	catenin (cadherin-associated protein), delta 1	3653	0.19
chr11_12490872_12491247	0.41	PARVA	parvin, alpha	16777	0.26
chr1_183014064_183014215	0.41	LAMC1	laminin, gamma 1 (formerly LAMB2)	21544	0.19
chr8_28347493_28348400	0.41	FBXO16	F-box protein 16	111	0.95
chr7_84814966_84815265	0.41	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	1056	0.71
chr1_103572231_103572444	0.41	COL11A1	collagen, type XI, alpha 1	1397	0.61
chr7_106787828_106787991	0.40	CTA-360L10.1		13731	0.2
chr1_79471738_79472138	0.40	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	465	0.9
chr4_20319822_20319973	0.40	SLIT2	slit homolog 2 (Drosophila)	63354	0.14
chr12_69635224_69635375	0.40	CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	1877	0.43
chr7_28429293_28429606	0.40	CREB5	cAMP responsive element binding protein 5	19557	0.28
chr18_34274069_34274303	0.40	FHOD3	formin homology 2 domain containing 3	24334	0.22
chr1_227504354_227504526	0.39	CDC42BPA	CDC42 binding protein kinase alpha (DMPK-like)	443	0.9
chr1_163039219_163039545	0.39	RGS4	regulator of G-protein signaling 4	231	0.96
chr18_32291325_32291476	0.39	DTNA	dystrobrevin, alpha	1139	0.62
chr3_33318777_33319866	0.39	FBXL2	F-box and leucine-rich repeat protein 2	353	0.91
chr5_140797768_140798225	0.39	PCDHGB7	protocadherin gamma subfamily B, 7	569	0.45
chr2_66670655_66670806	0.39	MEIS1	Meis homeobox 1	633	0.62
chr12_11980966_11981117	0.39	ETV6	ets variant 6	57830	0.15
chr5_98107866_98108017	0.39	RGMB-AS1	RGMB antisense RNA 1	541	0.73
chr4_152462150_152462592	0.39	FAM160A1	family with sequence similarity 160, member A1	8207	0.21
chr10_32097205_32097356	0.39	ARHGAP12	Rho GTPase activating protein 12	45828	0.16
chr1_98499845_98500395	0.39	ENSG00000225206	.	10787	0.31
chr15_52943707_52943982	0.38	FAM214A	family with sequence similarity 214, member A	403	0.82
chr5_107229567_107229740	0.38	ENSG00000251732	.	83323	0.11
chr4_138452050_138452321	0.38	PCDH18	protocadherin 18	1380	0.62
chr16_86542600_86543872	0.38	FOXF1	forkhead box F1	897	0.62
chr11_73022978_73023129	0.38	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	443	0.75
chr3_149094469_149095370	0.38	TM4SF1-AS1	TM4SF1 antisense RNA 1	646	0.47
chr2_189843684_189844024	0.38	ENSG00000221502	.	1036	0.57
chr13_106567585_106567736	0.38	ENSG00000252550	.	17668	0.3
chr16_85038693_85039085	0.38	ZDHHC7	zinc finger, DHHC-type containing 7	273	0.93
chr3_57128495_57128646	0.38	ARHGEF3	Rho guanine nucleotide exchange factor (GEF) 3	15234	0.16
chr12_50665639_50665877	0.38	LIMA1	LIM domain and actin binding 1	11509	0.13
chr10_104817675_104817826	0.38	NT5C2	5'-nucleotidase, cytosolic II	36375	0.18
chr3_16219029_16219297	0.38	GALNT15	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15	2947	0.33
chr13_111862424_111862612	0.38	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	4882	0.27
chr13_21654404_21654812	0.38	LATS2	large tumor suppressor kinase 2	18922	0.14
chr12_21981553_21981788	0.37	RP11-729I10.2		1526	0.43
chr1_182994178_182994360	0.37	LAMC1	laminin, gamma 1 (formerly LAMB2)	1674	0.39
chr2_201203716_201203867	0.37	SPATS2L	spermatogenesis associated, serine-rich 2-like	12121	0.21
chr12_85305887_85306488	0.37	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	384	0.92
chr2_158694184_158694335	0.37	ACVR1	activin A receptor, type I	531	0.79
chr4_187648403_187648661	0.37	FAT1	FAT atypical cadherin 1	656	0.82
chr6_45545466_45545617	0.37	ENSG00000252738	.	68300	0.13
chr4_55100810_55101099	0.37	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	4465	0.31
chr5_122620941_122621184	0.37	CEP120	centrosomal protein 120kDa	137935	0.04
chr18_52969288_52969439	0.37	TCF4	transcription factor 4	494	0.88
chr1_178096168_178096398	0.37	RASAL2	RAS protein activator like 2	33007	0.24
chr11_131780111_131780399	0.37	NTM	neurotrimin	642	0.77
chr3_100785098_100785499	0.37	ABI3BP	ABI family, member 3 (NESH) binding protein	72939	0.11
chr1_243397464_243397615	0.37	AC092782.1	Uncharacterized protein	9481	0.18
chr4_74087462_74087866	0.37	ANKRD17	ankyrin repeat domain 17	1167	0.53
chr5_65097013_65097416	0.37	NLN	neurolysin (metallopeptidase M3 family)	13024	0.24
chr2_202901632_202901854	0.37	FZD7	frizzled family receptor 7	2433	0.27
chrX_133681520_133681671	0.37	ENSG00000223749	.	854	0.38
chr2_83792091_83792242	0.36	ENSG00000199295	.	92693	0.1
chr2_192547404_192547681	0.36	NABP1	nucleic acid binding protein 1	3826	0.35
chr19_31153583_31153756	0.36	ENSG00000223148	.	48542	0.19
chr19_57793910_57794061	0.36	ZNF460	zinc finger protein 460	730	0.49
chr13_27580824_27581277	0.36	USP12-AS1	USP12 antisense RNA 1	155942	0.03
chr1_170634990_170635141	0.36	PRRX1	paired related homeobox 1	1987	0.46
chr10_33621519_33621932	0.36	NRP1	neuropilin 1	1585	0.49
chr18_7568558_7569022	0.36	PTPRM	protein tyrosine phosphatase, receptor type, M	973	0.7
chr6_27463085_27463306	0.36	ZNF184	zinc finger protein 184	22298	0.21
chr2_167232459_167233133	0.36	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	293	0.93
chr9_95610621_95610772	0.36	ZNF484	zinc finger protein 484	7904	0.17
chr2_210444017_210444208	0.36	MAP2	microtubule-associated protein 2	33	0.99
chrX_114467670_114468385	0.36	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	601	0.77
chr8_102184368_102184618	0.36	ZNF706	zinc finger protein 706	29392	0.19
chr20_43971537_43971915	0.36	SDC4	syndecan 4	5338	0.13
chr7_23043442_23043593	0.36	FAM126A	family with sequence similarity 126, member A	10176	0.26
chr6_19691587_19692480	0.36	ENSG00000200957	.	49273	0.18
chr8_107738582_107738843	0.36	OXR1	oxidation resistance 1	299	0.9
chr18_52985449_52985614	0.36	TCF4	transcription factor 4	3686	0.35
chr8_49833115_49833392	0.36	SNAI2	snail family zinc finger 2	735	0.8
chr1_243415347_243415602	0.35	CEP170	centrosomal protein 170kDa	1148	0.47
chr21_17568461_17568771	0.35	ENSG00000201025	.	88473	0.1
chr13_76211856_76212147	0.35	LMO7	LIM domain 7	1542	0.32
chr6_132271007_132271170	0.35	RP11-69I8.3		998	0.48
chrX_34673071_34673254	0.35	TMEM47	transmembrane protein 47	2243	0.48
chr9_35539291_35539516	0.35	RUSC2	RUN and SH3 domain containing 2	774	0.57
chr7_14020163_14020323	0.35	ETV1	ets variant 1	5823	0.29
chr1_94701941_94702122	0.35	ARHGAP29	Rho GTPase activating protein 29	1090	0.6
chr3_98616545_98616732	0.35	DCBLD2	discoidin, CUB and LCCL domain containing 2	3377	0.22
chr2_218807657_218808117	0.35	TNS1	tensin 1	906	0.64
chr2_66672542_66672972	0.35	MEIS1	Meis homeobox 1	2660	0.22
chr9_18474095_18474958	0.35	ADAMTSL1	ADAMTS-like 1	295	0.95
chr9_72659780_72659962	0.35	MAMDC2	MAM domain containing 2	1374	0.52
chr16_87490664_87491008	0.35	ZCCHC14	zinc finger, CCHC domain containing 14	24096	0.15
chr14_100260565_100260825	0.35	EML1	echinoderm microtubule associated protein like 1	923	0.67
chr1_161991656_161991887	0.35	OLFML2B	olfactomedin-like 2B	1659	0.44
chr6_56111778_56112295	0.34	COL21A1	collagen, type XXI, alpha 1	199	0.97
chr7_132738813_132738964	0.34	CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3	27912	0.2
chr15_57512771_57512922	0.34	TCF12	transcription factor 12	1182	0.6
chr13_33162802_33163103	0.34	PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	2388	0.38
chr1_62305298_62305449	0.34	ENSG00000212360	.	12798	0.22
chr2_46928125_46928276	0.34	SOCS5	suppressor of cytokine signaling 5	1874	0.38
chr14_50819908_50820192	0.34	CDKL1	cyclin-dependent kinase-like 1 (CDC2-related kinase)	12203	0.17
chr5_15620950_15621349	0.34	FBXL7	F-box and leucine-rich repeat protein 7	5058	0.28
chr1_82267993_82268232	0.34	LPHN2	latrophilin 2	2030	0.49
chr15_79172438_79172758	0.34	MORF4L1	mortality factor 4 like 1	2016	0.31
chr15_33131422_33131795	0.34	FMN1	formin 1	48847	0.14
chr2_190075633_190075814	0.34	COL5A2	collagen, type V, alpha 2	31118	0.2
chr5_43310867_43311162	0.34	HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	2312	0.32
chr7_62828662_62828813	0.34	AC006455.1		19498	0.21
chr4_120599875_120600080	0.33	PDE5A	phosphodiesterase 5A, cGMP-specific	49831	0.17
chr14_27065632_27065895	0.33	NOVA1	neuro-oncological ventral antigen 1	482	0.74
chr1_229480055_229480206	0.33	CCSAP	centriole, cilia and spindle-associated protein	1395	0.36
chr11_121593168_121593875	0.33	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	132393	0.05
chr5_98396547_98396924	0.33	ENSG00000200351	.	124284	0.06

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	2.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.4	1.6	GO:0043589	skin morphogenesis(GO:0043589)
0.4	1.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.3	0.9	GO:1900116	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.3	0.9	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.3	0.3	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.3	2.2	GO:0060216	definitive hemopoiesis(GO:0060216)
0.3	0.8	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	1.2	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.2	0.5	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.2	0.6	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.2	0.8	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.2	0.8	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.2	0.8	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2	0.5	GO:1903332	regulation of protein folding(GO:1903332)
0.2	0.5	GO:0010842	retina layer formation(GO:0010842)
0.2	0.3	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.2	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.2	0.2	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.2	0.5	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.1	GO:0060028	convergent extension involved in axis elongation(GO:0060028)
0.1	0.6	GO:0010107	potassium ion import(GO:0010107)
0.1	0.7	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1	0.3	GO:0060437	lung growth(GO:0060437)
0.1	0.4	GO:0060676	ureteric bud formation(GO:0060676)
0.1	0.7	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.1	0.6	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	1.8	GO:0042474	middle ear morphogenesis(GO:0042474)
0.1	0.4	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	3.0	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.4	GO:0033023	mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.1	0.5	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.5	GO:0008218	bioluminescence(GO:0008218)
0.1	0.4	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.1	0.4	GO:0030859	polarized epithelial cell differentiation(GO:0030859) establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1	0.6	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.1	0.1	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.4	GO:0060433	bronchus development(GO:0060433)
0.1	0.5	GO:0043615	astrocyte cell migration(GO:0043615)
0.1	0.4	GO:0031167	rRNA methylation(GO:0031167)
0.1	0.1	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.3	GO:0060242	contact inhibition(GO:0060242)
0.1	0.7	GO:0097061	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.3	GO:0006154	adenosine catabolic process(GO:0006154)
0.1	0.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.3	GO:0061299	retina vasculature development in camera-type eye(GO:0061298) retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1	0.6	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.5	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.2	GO:0010659	striated muscle cell apoptotic process(GO:0010658) cardiac muscle cell apoptotic process(GO:0010659) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664) regulation of cardiac muscle cell apoptotic process(GO:0010665) negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.1	0.9	GO:0045885	obsolete positive regulation of survival gene product expression(GO:0045885)
0.1	0.3	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.1	0.3	GO:0001553	luteinization(GO:0001553)
0.1	0.3	GO:0036072	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1	0.4	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	0.3	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.1	0.3	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.1	0.1	GO:0001743	optic placode formation(GO:0001743)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.7	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1	0.4	GO:0070141	response to UV-A(GO:0070141)
0.1	0.3	GO:0032347	regulation of ketone biosynthetic process(GO:0010566) regulation of aldosterone metabolic process(GO:0032344) regulation of aldosterone biosynthetic process(GO:0032347)
0.1	0.3	GO:0045627	positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.1	0.1	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.1	0.4	GO:0070091	glucagon secretion(GO:0070091)
0.1	0.2	GO:0002689	negative regulation of leukocyte chemotaxis(GO:0002689)
0.1	0.1	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.5	GO:0021984	adenohypophysis development(GO:0021984)
0.1	0.3	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.1	0.1	GO:0045683	negative regulation of epidermis development(GO:0045683)
0.1	1.3	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.1	0.4	GO:0016264	gap junction assembly(GO:0016264)
0.1	0.3	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.1	0.3	GO:0001945	lymph vessel development(GO:0001945)
0.1	0.3	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.2	GO:0051968	positive regulation of synaptic transmission, glutamatergic(GO:0051968)
0.1	0.3	GO:0007258	JUN phosphorylation(GO:0007258)
0.1	0.2	GO:0031223	response to auditory stimulus(GO:0010996) auditory behavior(GO:0031223)
0.1	0.2	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	1.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.1	0.2	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.1	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	0.2	GO:0070874	negative regulation of glycogen metabolic process(GO:0070874)
0.1	0.2	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.1	0.2	GO:1904251	regulation of bile acid biosynthetic process(GO:0070857) regulation of bile acid metabolic process(GO:1904251)
0.1	0.2	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.1	GO:0048853	forebrain morphogenesis(GO:0048853)
0.1	0.5	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.2	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.1	GO:2000542	negative regulation of gastrulation(GO:2000542)
0.1	0.6	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0019934	cGMP-mediated signaling(GO:0019934)
0.1	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.3	GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1	0.1	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.1	GO:0010761	fibroblast migration(GO:0010761)
0.1	0.3	GO:0001757	somite specification(GO:0001757)
0.1	0.1	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.3	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.1	0.4	GO:0048844	artery morphogenesis(GO:0048844)
0.1	0.2	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.1	0.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.3	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1	0.2	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.1	0.5	GO:0032332	positive regulation of chondrocyte differentiation(GO:0032332)
0.1	0.2	GO:0051451	myoblast migration(GO:0051451)
0.1	0.2	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.3	GO:0008354	germ cell migration(GO:0008354)
0.1	0.1	GO:0003161	cardiac conduction system development(GO:0003161)
0.1	0.3	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.1	0.3	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.1	0.6	GO:0035329	hippo signaling(GO:0035329)
0.1	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.1	1.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.1	GO:0060748	tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1	0.2	GO:0051931	regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1	0.2	GO:0021889	olfactory bulb interneuron differentiation(GO:0021889)
0.1	0.2	GO:0032506	cytokinetic process(GO:0032506)
0.1	0.1	GO:0048755	branching morphogenesis of a nerve(GO:0048755)
0.1	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.1	0.2	GO:0043267	negative regulation of potassium ion transport(GO:0043267)
0.1	0.1	GO:0032413	negative regulation of ion transmembrane transporter activity(GO:0032413)
0.1	0.4	GO:0015886	heme transport(GO:0015886)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	0.3	GO:0060347	heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.1	0.4	GO:0015871	choline transport(GO:0015871)
0.1	0.1	GO:0070366	regulation of hepatocyte differentiation(GO:0070366)
0.1	0.2	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.1	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.1	GO:0033860	regulation of NAD(P)H oxidase activity(GO:0033860)
0.1	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.1	GO:0060013	righting reflex(GO:0060013)
0.0	0.1	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.2	GO:0032292	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.3	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0	0.2	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0071481	cellular response to X-ray(GO:0071481)
0.0	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.1	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.6	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.0	0.1	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.0	GO:0072070	loop of Henle development(GO:0072070)
0.0	0.3	GO:0001573	ganglioside metabolic process(GO:0001573)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.2	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
0.0	0.0	GO:0051124	synaptic growth at neuromuscular junction(GO:0051124)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.5	GO:0001738	morphogenesis of a polarized epithelium(GO:0001738)
0.0	0.2	GO:0015732	prostaglandin transport(GO:0015732)
0.0	0.2	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.0	GO:0003207	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.2	GO:0008347	glial cell migration(GO:0008347)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.1	GO:0071569	protein ufmylation(GO:0071569)
0.0	0.0	GO:0007132	meiotic metaphase I(GO:0007132)
0.0	0.2	GO:0098810	neurotransmitter reuptake(GO:0098810)
0.0	0.1	GO:0060638	mesenchymal-epithelial cell signaling(GO:0060638)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.1	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.7	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:0072133	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.2	GO:0007351	tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	5.3	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0090192	cellular response to heparin(GO:0071504) regulation of glomerulus development(GO:0090192)
0.0	0.0	GO:0050919	negative chemotaxis(GO:0050919)
0.0	0.0	GO:0002248	connective tissue replacement involved in inflammatory response wound healing(GO:0002248) connective tissue replacement(GO:0097709)
0.0	0.2	GO:0048566	embryonic digestive tract development(GO:0048566)
0.0	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.2	GO:0030321	transepithelial chloride transport(GO:0030321)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:0009296	obsolete flagellum assembly(GO:0009296)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0048488	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.4	GO:0030866	cortical actin cytoskeleton organization(GO:0030866)
0.0	0.1	GO:0090047	obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0	0.0	GO:0072498	embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.0	0.1	GO:0043268	positive regulation of potassium ion transport(GO:0043268)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0007100	mitotic centrosome separation(GO:0007100)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0001840	neural plate morphogenesis(GO:0001839) neural plate development(GO:0001840)
0.0	0.1	GO:0010661	positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0009648	photoperiodism(GO:0009648)
0.0	0.1	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.1	GO:0044415	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.0	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.2	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.2	GO:2000144	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.1	GO:0032823	natural killer cell differentiation(GO:0001779) regulation of natural killer cell differentiation(GO:0032823) positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.2	GO:0010171	body morphogenesis(GO:0010171)
0.0	0.2	GO:0021511	spinal cord patterning(GO:0021511)
0.0	0.2	GO:0045780	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.5	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0044705	mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0	0.1	GO:0042713	sperm ejaculation(GO:0042713)
0.0	0.1	GO:0018214	peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0	0.6	GO:0007215	glutamate receptor signaling pathway(GO:0007215)
0.0	0.1	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
0.0	0.1	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.0	0.5	GO:0007566	embryo implantation(GO:0007566)
0.0	0.3	GO:0061515	erythrocyte development(GO:0048821) myeloid cell development(GO:0061515)
0.0	0.1	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0032455	nerve growth factor processing(GO:0032455)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.2	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.2	GO:0019720	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.6	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.2	GO:0048265	response to pain(GO:0048265)
0.0	0.4	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.1	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:0021571	rhombomere 5 development(GO:0021571)
0.0	0.1	GO:0021978	telencephalon regionalization(GO:0021978)
0.0	0.0	GO:0042268	regulation of cytolysis(GO:0042268)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.4	GO:0009954	proximal/distal pattern formation(GO:0009954)
0.0	0.2	GO:0050922	negative regulation of chemotaxis(GO:0050922)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0043030	regulation of macrophage activation(GO:0043030)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.5	GO:0070374	positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0	0.1	GO:0060236	regulation of mitotic spindle organization(GO:0060236)
0.0	0.1	GO:0021772	olfactory bulb development(GO:0021772)
0.0	0.1	GO:0003091	renal water homeostasis(GO:0003091)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0045915	positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.3	GO:0051353	positive regulation of oxidoreductase activity(GO:0051353)
0.0	0.9	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.2	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0001660	fever generation(GO:0001660)
0.0	0.1	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0051973	positive regulation of telomerase activity(GO:0051973)
0.0	0.1	GO:0040036	regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0	0.1	GO:0032148	activation of protein kinase B activity(GO:0032148)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.2	GO:0002070	epithelial cell maturation(GO:0002070)
0.0	0.0	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0008291	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0035136	forelimb morphogenesis(GO:0035136)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.0	0.1	GO:0031000	response to caffeine(GO:0031000)
0.0	0.0	GO:0090025	regulation of monocyte chemotaxis(GO:0090025) positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.3	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0002076	osteoblast development(GO:0002076)
0.0	0.0	GO:0060911	cardiac cell fate commitment(GO:0060911)
0.0	0.2	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.1	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0010966	regulation of phosphate transport(GO:0010966)
0.0	0.0	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.1	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0031529	ruffle organization(GO:0031529)
0.0	0.0	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.0	GO:0032224	regulation of synaptic transmission, cholinergic(GO:0032222) positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0035176	social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0	0.2	GO:0006972	hyperosmotic response(GO:0006972)
0.0	0.0	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.4	GO:0006760	folic acid-containing compound metabolic process(GO:0006760)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.1	GO:0090399	replicative senescence(GO:0090399)
0.0	0.0	GO:0046877	regulation of saliva secretion(GO:0046877)
0.0	0.0	GO:0090201	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.0	GO:0072338	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.1	GO:0007379	segment specification(GO:0007379)
0.0	0.1	GO:0051014	actin filament severing(GO:0051014)
0.0	0.0	GO:0021794	thalamus development(GO:0021794)
0.0	0.1	GO:0007512	adult heart development(GO:0007512)
0.0	0.1	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	1.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.0	0.0	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.3	GO:0045103	intermediate filament-based process(GO:0045103)
0.0	0.1	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0098657	neurotransmitter uptake(GO:0001504) import into cell(GO:0098657)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.1	GO:0046622	positive regulation of organ growth(GO:0046622)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0016103	diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0046349	amino sugar biosynthetic process(GO:0046349)
0.0	0.1	GO:0030539	male genitalia development(GO:0030539)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.4	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.3	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	0.2	GO:0006949	syncytium formation(GO:0006949)
0.0	0.0	GO:0021591	ventricular system development(GO:0021591)
0.0	0.1	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0015825	L-serine transport(GO:0015825)
0.0	0.0	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0031122	cytoplasmic microtubule organization(GO:0031122)
0.0	0.1	GO:0006108	malate metabolic process(GO:0006108)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.0	GO:0043113	receptor clustering(GO:0043113)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.1	GO:0016093	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0	0.0	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.0	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.0	GO:0048311	mitochondrion distribution(GO:0048311)
0.0	0.1	GO:0033189	response to vitamin A(GO:0033189)
0.0	0.2	GO:0021549	cerebellum development(GO:0021549)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:1901978	positive regulation of spindle checkpoint(GO:0090232) regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) positive regulation of cell cycle checkpoint(GO:1901978) regulation of mitotic spindle checkpoint(GO:1903504)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.0	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.1	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.0	GO:0045188	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.0	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.0	GO:0043084	penile erection(GO:0043084)
0.0	0.1	GO:0090659	adult walking behavior(GO:0007628) walking behavior(GO:0090659)
0.0	0.0	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.3	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.0	GO:0003010	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0	0.1	GO:0046642	negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0	0.0	GO:0048630	skeletal muscle tissue growth(GO:0048630)
0.0	0.1	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.0	0.6	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0	0.0	GO:0036336	dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0006188	IMP biosynthetic process(GO:0006188) IMP metabolic process(GO:0046040)
0.0	0.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.3	GO:0001843	neural tube closure(GO:0001843)
0.0	0.0	GO:0007442	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.2	GO:0030178	negative regulation of Wnt signaling pathway(GO:0030178)
0.0	0.0	GO:0033599	regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.0	0.3	GO:0006584	catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.1	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0019730	antimicrobial humoral response(GO:0019730)
0.0	0.0	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.0	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0	0.0	GO:0033004	negative regulation of mast cell activation(GO:0033004)
0.0	0.0	GO:0032776	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	1.0	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.0	0.2	GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0	0.1	GO:0030488	tRNA methylation(GO:0030488)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:1903115	regulation of muscle filament sliding(GO:0032971) regulation of actin filament-based movement(GO:1903115)
0.0	0.2	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.3	GO:0017156	calcium ion regulated exocytosis(GO:0017156)
0.0	0.0	GO:0031282	regulation of guanylate cyclase activity(GO:0031282)
0.0	0.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.0	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.0	0.0	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.0	GO:0032527	protein exit from endoplasmic reticulum(GO:0032527)
0.0	0.0	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.1	GO:0042461	eye photoreceptor cell differentiation(GO:0001754) photoreceptor cell development(GO:0042461) eye photoreceptor cell development(GO:0042462)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.0	GO:0033630	positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0	0.2	GO:0009584	detection of visible light(GO:0009584)
0.0	0.2	GO:0009988	cell-cell recognition(GO:0009988)
0.0	0.1	GO:0045844	positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.7	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.0	GO:0039656	modulation by virus of host gene expression(GO:0039656)
0.0	0.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0007021	tubulin complex assembly(GO:0007021)
0.0	0.0	GO:0010611	regulation of cardiac muscle hypertrophy(GO:0010611)
0.0	0.0	GO:0070307	lens fiber cell development(GO:0070307)
0.0	0.0	GO:0060008	Sertoli cell differentiation(GO:0060008) Sertoli cell development(GO:0060009)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	2.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2	0.7	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	0.6	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.2	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.2	0.5	GO:0030934	anchoring collagen complex(GO:0030934)
0.2	0.8	GO:0071437	invadopodium(GO:0071437)
0.2	0.5	GO:0043259	laminin-10 complex(GO:0043259)
0.1	1.1	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.4	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.9	GO:0098644	complex of collagen trimers(GO:0098644)
0.1	0.4	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.1	0.4	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.8	GO:0005916	fascia adherens(GO:0005916)
0.1	0.6	GO:0005581	collagen trimer(GO:0005581)
0.1	0.5	GO:0001527	microfibril(GO:0001527)
0.1	1.7	GO:0005811	lipid particle(GO:0005811)
0.1	0.5	GO:0031430	M band(GO:0031430)
0.1	0.2	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.3	GO:0016342	catenin complex(GO:0016342)
0.1	0.9	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1	0.3	GO:0032059	bleb(GO:0032059)
0.1	0.1	GO:0070852	cell body fiber(GO:0070852)
0.1	0.1	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.1	0.5	GO:0008091	spectrin(GO:0008091)
0.1	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.1	0.1	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.1	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.3	GO:0030122	AP-2 adaptor complex(GO:0030122) clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0060200	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0	3.3	GO:0030027	lamellipodium(GO:0030027)
0.0	10.7	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.2	GO:0016011	dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.3	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	1.0	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.2	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.5	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	2.2	GO:0030016	myofibril(GO:0030016)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0043083	synaptic cleft(GO:0043083)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0033270	paranode region of axon(GO:0033270)
0.0	1.7	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.2	GO:0070652	HAUS complex(GO:0070652)
0.0	1.0	GO:0030426	growth cone(GO:0030426)
0.0	1.9	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.0	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.5	GO:0008305	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0031941	filamentous actin(GO:0031941)
0.0	0.1	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	2.7	GO:0005911	cell-cell junction(GO:0005911)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.3	GO:0005902	microvillus(GO:0005902)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0045120	pronucleus(GO:0045120)
0.0	2.9	GO:0005667	transcription factor complex(GO:0005667)
0.0	0.4	GO:0016459	myosin complex(GO:0016459)
0.0	1.0	GO:0005875	microtubule associated complex(GO:0005875)
0.0	0.5	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.0	GO:0044447	axoneme part(GO:0044447)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	2.0	GO:0001099	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.6	1.7	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	1.3	GO:0045499	chemorepellent activity(GO:0045499)
0.3	0.8	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	0.9	GO:0050815	phosphoserine binding(GO:0050815)
0.2	0.6	GO:0002162	dystroglycan binding(GO:0002162)
0.2	2.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.2	0.8	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.2	0.6	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.2	0.9	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.2	0.6	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2	0.6	GO:0030172	troponin C binding(GO:0030172)
0.1	1.0	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.1	0.4	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.4	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.7	GO:0017154	semaphorin receptor activity(GO:0017154)
0.1	1.1	GO:0017166	vinculin binding(GO:0017166)
0.1	0.4	GO:0032554	purine deoxyribonucleotide binding(GO:0032554) adenyl deoxyribonucleotide binding(GO:0032558)
0.1	0.7	GO:0030507	spectrin binding(GO:0030507)
0.1	0.5	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.5	GO:0042805	actinin binding(GO:0042805)
0.1	0.3	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1	0.3	GO:0042910	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.8	GO:0005110	frizzled-2 binding(GO:0005110)
0.1	0.4	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	1.1	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.5	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.1	0.3	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.1	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1	0.5	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.1	0.2	GO:0043559	insulin binding(GO:0043559)
0.1	0.3	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.1	0.8	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.4	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.1	0.5	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.3	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.1	0.3	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.3	GO:0004083	bisphosphoglycerate mutase activity(GO:0004082) bisphosphoglycerate 2-phosphatase activity(GO:0004083) phosphoglycerate mutase activity(GO:0004619)
0.1	0.4	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.4	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.4	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1	0.2	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.1	0.2	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.4	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	0.2	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	1.2	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.9	GO:0043394	proteoglycan binding(GO:0043394)
0.1	0.3	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1	0.8	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.3	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.1	0.8	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.3	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.1	0.2	GO:0004470	malic enzyme activity(GO:0004470)
0.1	0.3	GO:0001968	fibronectin binding(GO:0001968)
0.1	0.2	GO:0031628	opioid receptor binding(GO:0031628)
0.1	0.2	GO:0004803	transposase activity(GO:0004803)
0.1	0.3	GO:0004994	somatostatin receptor activity(GO:0004994)
0.1	0.1	GO:0045545	syndecan binding(GO:0045545)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.8	GO:0043498	obsolete cell surface binding(GO:0043498)
0.1	0.1	GO:0050682	AF-2 domain binding(GO:0050682)
0.1	0.3	GO:0070700	BMP receptor binding(GO:0070700)
0.1	3.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.1	0.4	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1	0.9	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.1	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.8	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.1	1.0	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0051636	obsolete Gram-negative bacterial cell surface binding(GO:0051636)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.2	GO:0009374	biotin binding(GO:0009374)
0.0	0.3	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.5	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	1.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.2	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.4	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.3	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.4	GO:0051378	serotonin binding(GO:0051378)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.4	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.5	GO:0045296	cadherin binding(GO:0045296)
0.0	0.3	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.2	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.4	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	0.2	GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.4	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0	0.3	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.4	GO:0034739	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.2	GO:0008517	folic acid transporter activity(GO:0008517)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004980	melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.2	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.1	GO:0016901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0	0.1	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.3	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	2.4	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.3	GO:0005035	death receptor activity(GO:0005035)
0.0	0.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.5	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.1	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.2	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0070325	lipoprotein particle receptor binding(GO:0070325)
0.0	0.1	GO:0016933	extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0	0.2	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.2	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0015149	hexose transmembrane transporter activity(GO:0015149)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.4	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0051184	cofactor transporter activity(GO:0051184)
0.0	0.1	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.1	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.3	GO:0005212	structural constituent of eye lens(GO:0005212)
0.0	0.1	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	1.3	GO:0008201	heparin binding(GO:0008201)
0.0	1.9	GO:0008083	growth factor activity(GO:0008083)
0.0	0.0	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0048039	ubiquinone binding(GO:0048039)
0.0	0.2	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0004683	calmodulin-dependent protein kinase activity(GO:0004683)
0.0	0.6	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.0	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.1	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.0	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0005251	delayed rectifier potassium channel activity(GO:0005251)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.1	GO:0031490	chromatin DNA binding(GO:0031490)
0.0	0.0	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.1	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.0	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0	1.8	GO:0008237	metallopeptidase activity(GO:0008237)
0.0	0.1	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0004739	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	3.4	GO:0030528	obsolete transcription regulator activity(GO:0030528)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.0	GO:0016885	CoA carboxylase activity(GO:0016421) ligase activity, forming carbon-carbon bonds(GO:0016885)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.0	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	NABA COLLAGENS	Genes encoding collagen proteins
0.1	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	0.9	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.1	1.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1	1.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	1.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.1	1.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	1.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.9	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.8	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.4	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.9	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	4.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.6	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	1.0	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.4	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.5	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.3	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.1	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.4	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.2	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.1	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	2.8	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	4.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.2	2.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	1.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.6	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.1	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	0.7	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	0.6	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	0.9	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	0.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	3.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	0.7	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	0.2	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.1	1.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.1	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1	0.5	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1	0.6	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.1	0.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	0.7	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.7	REACTOME PEPTIDE HORMONE BIOSYNTHESIS	Genes involved in Peptide hormone biosynthesis
0.0	0.3	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.9	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.2	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0	0.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.3	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.1	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME LATE PHASE OF HIV LIFE CYCLE	Genes involved in Late Phase of HIV Life Cycle
0.0	0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.3	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.3	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.3	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	0.0	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.2	REACTOME G ALPHA1213 SIGNALLING EVENTS	Genes involved in G alpha (12/13) signalling events
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.3	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.3	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.3	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.9	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.1	REACTOME REGULATION OF MITOTIC CELL CYCLE	Genes involved in Regulation of mitotic cell cycle
0.0	0.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.0	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C

Results for ISL1

Z-value: 2.81

Motif logo

Transcription factors associated with ISL1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the ISL1 motif across conditions

Conditions sorted by the z-value of the ISL1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of ISL1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: