Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for ISX

Z-value: 1.07

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Transcription factors associated with ISX

Gene Symbol Gene ID Gene Info
ISX
ENSG00000175329.8 ISX

Activity of the ISX motif across conditions

Conditions sorted by the z-value of the ISX motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_25041553_25042305 0.80 RP3-425P12.5
138
 0.72
chr7_50348449_50348781 0.78 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 297
 0.94
chr7_50345819_50346403 0.76 IKZF1
 IKAROS family zinc finger 1 (Ikaros)
 1733
 0.5
chr22_40858929_40859404 0.72 MKL1
 megakaryoblastic leukemia (translocation) 1
 256
 0.92
chr7_150149402_150149565 0.71 GIMAP8
 GTPase, IMAP family member 8
 1765
 0.33
chr7_139555848_139556033 0.71 TBXAS1
 thromboxane A synthase 1 (platelet)
 26830
 0.22
chr5_130882612_130883040 0.71 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
 14100
 0.29
chr14_88471433_88472132 0.69 GPR65
 G protein-coupled receptor 65
 314
 0.88
chr5_118606885_118607036 0.68 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 2511
 0.28
chr5_159896012_159896214 0.68 ENSG00000265237
 .
 5296
 0.18
chr6_16486388_16486539 0.67 ENSG00000265642
 .
 57709
 0.16
chr15_80258993_80259144 0.67 BCL2A1
 BCL2-related protein A1
 4443
 0.21
chr13_99957828_99957979 0.66 GPR183
 G protein-coupled receptor 183
 1756
 0.38
chr2_106776042_106776232 0.66 UXS1
 UDP-glucuronate decarboxylase 1
 903
 0.66
chr7_106507255_106507406 0.65 PIK3CG
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
 1406
 0.54
chr5_108745860_108746027 0.65 PJA2
 praja ring finger 2, E3 ubiquitin protein ligase
 248
 0.96
chr3_108543496_108543820 0.64 TRAT1
 T cell receptor associated transmembrane adaptor 1
 2039
 0.42
chrX_9801459_9801610 0.64 ENSG00000206844
 .
 41207
 0.15
chr5_118606012_118606179 0.60 TNFAIP8
 tumor necrosis factor, alpha-induced protein 8
 1646
 0.37
chr9_117721707_117721858 0.59 TNFSF8
 tumor necrosis factor (ligand) superfamily, member 8
 29085
 0.23
chr22_40322756_40322951 0.59 GRAP2
 GRB2-related adaptor protein 2
 212
 0.93
chr9_80524074_80524374 0.58 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 86309
 0.1
chr7_115668295_115668446 0.58 TFEC
 transcription factor EC
 2425
 0.43
chr5_126094279_126094440 0.58 ENSG00000252185
 .
 3250
 0.29
chr17_10601145_10601947 0.58 ADPRM
 ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
 635
 0.41
chr14_22974481_22974956 0.58 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 18547
 0.09
chr6_26198173_26198564 0.57 HIST1H3D
 histone cluster 1, H3d
 890
 0.22
chr4_40201423_40201705 0.55 RHOH
 ras homolog family member H
 400
 0.87
chr1_66806017_66806168 0.55 PDE4B
 phosphodiesterase 4B, cAMP-specific
 8220
 0.31
chr7_3134520_3134947 0.53 CARD11
 caspase recruitment domain family, member 11
 51154
 0.14
chr1_109236074_109236443 0.53 PRPF38B
 pre-mRNA processing factor 38B
 1295
 0.4
chr11_118215473_118215625 0.53 CD3G
 CD3g molecule, gamma (CD3-TCR complex)
 478
 0.67
chr1_225610206_225610357 0.52 LBR
 lamin B receptor
 5318
 0.2
chr2_143907810_143908037 0.52 ARHGAP15
 Rho GTPase activating protein 15
 21040
 0.22
chr1_234544831_234544982 0.52 COA6
 cytochrome c oxidase assembly factor 6 homolog (S. cerevisiae)
 35459
 0.12
chr1_206732541_206732911 0.52 RASSF5
 Ras association (RalGDS/AF-6) domain family member 5
 2233
 0.27
chrX_30594869_30596024 0.51 CXorf21
 chromosome X open reading frame 21
 515
 0.84
chr20_1357596_1357769 0.51 RP11-314N13.3
15416
 0.13
chr6_154568354_154568864 0.50 IPCEF1
 interaction protein for cytohesin exchange factors 1
 53
 0.99
chr1_160614457_160614608 0.50 SLAMF1
 signaling lymphocytic activation molecule family member 1
 2279
 0.26
chr10_46075820_46076565 0.50 MARCH8
 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
 13747
 0.25
chr2_204571383_204571580 0.50 CD28
 CD28 molecule
 65
 0.98
chr10_70847938_70848765 0.49 SRGN
 serglycin
 477
 0.82
chr2_64500903_64501472 0.49 AC074289.1
45585
 0.16
chr6_130391698_130391967 0.49 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
 50130
 0.15
chr8_134086774_134086935 0.48 SLA
 Src-like-adaptor
 14251
 0.23
chr2_43447644_43447906 0.48 ZFP36L2
 ZFP36 ring finger protein-like 2
 5973
 0.25
chrX_97903125_97903276 0.48 ENSG00000252430
 .
 737074
 0.0
chrX_78400540_78401325 0.48 GPR174
 G protein-coupled receptor 174
 25537
 0.27
chr13_50114703_50115207 0.48 RCBTB1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 26504
 0.17
chr10_21501235_21501386 0.48 NEBL-AS1
 NEBL antisense RNA 1
 38027
 0.16
chr3_16883621_16883873 0.48 PLCL2
 phospholipase C-like 2
 42705
 0.19
chr20_55965224_55965375 0.48 RBM38
 RNA binding motif protein 38
 1164
 0.39
chr1_28975271_28975442 0.47 ENSG00000270103
 .
 244
 0.88
chr22_50523508_50523892 0.47 MLC1
 megalencephalic leukoencephalopathy with subcortical cysts 1
 12
 0.97
chr10_70850849_70851349 0.47 SRGN
 serglycin
 3225
 0.25
chr3_107697576_107697727 0.47 CD47
 CD47 molecule
 79557
 0.11
chr4_6919199_6919395 0.46 TBC1D14
 TBC1 domain family, member 14
 7322
 0.19
chr2_175458036_175458370 0.46 WIPF1
 WAS/WASL interacting protein family, member 1
 4290
 0.21
chr5_171560548_171560699 0.46 ENSG00000266671
 .
 52643
 0.12
chr18_60979364_60979515 0.46 RP11-28F1.2
1876
 0.31
chr11_128589269_128589524 0.46 SENCR
 smooth muscle and endothelial cell enriched migration/differentiation-associated long non-coding RNA
 23478
 0.17
chr13_49065751_49065929 0.46 RCBTB2
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
 41373
 0.17
chr6_49794571_49794884 0.46 RP3-417L20.4
9584
 0.19
chr17_74564111_74564262 0.45 RP11-666A8.9
1688
 0.17
chr4_141016416_141017006 0.45 RP11-392B6.1
32458
 0.2
chr2_235359483_235359634 0.45 ARL4C
 ADP-ribosylation factor-like 4C
 45686
 0.21
chr3_71539044_71539195 0.45 ENSG00000221264
 .
 52121
 0.14
chr5_131756798_131756949 0.45 AC116366.5
5273
 0.14
chr19_12724429_12724680 0.45 ZNF791
 zinc finger protein 791
 2786
 0.13
chr20_48328141_48328292 0.45 B4GALT5
 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
 2199
 0.3
chr13_46745397_46745548 0.45 ENSG00000240767
 .
 1589
 0.32
chr3_98253310_98253461 0.45 GPR15
 G protein-coupled receptor 15
 2642
 0.21
chr18_74837172_74837323 0.45 MBP
 myelin basic protein
 2421
 0.42
chr3_151961363_151961565 0.44 MBNL1
 muscleblind-like splicing regulator 1
 24365
 0.2
chr1_29253817_29254129 0.43 EPB41
 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
 12882
 0.18
chr5_74615521_74615672 0.43 HMGCR
 3-hydroxy-3-methylglutaryl-CoA reductase
 16558
 0.19
chrX_53711459_53711652 0.43 HUWE1
 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
 441
 0.89
chr14_32672268_32672419 0.42 ENSG00000202337
 .
 132
 0.94
chr17_18204377_18204528 0.42 TOP3A
 topoisomerase (DNA) III alpha
 1531
 0.27
chrX_78620994_78621299 0.42 ITM2A
 integral membrane protein 2A
 1710
 0.55
chr9_70851276_70851465 0.42 CBWD3
 COBW domain containing 3
 5027
 0.19
chr12_54891959_54892179 0.42 NCKAP1L
 NCK-associated protein 1-like
 499
 0.73
chr3_43329409_43329595 0.42 SNRK
 SNF related kinase
 1424
 0.43
chr7_37011253_37011404 0.42 ELMO1
 engulfment and cell motility 1
 13337
 0.2
chr3_121555276_121555427 0.42 EAF2
 ELL associated factor 2
 1267
 0.36
chr9_184434_184636 0.42 CBWD1
 COBW domain containing 1
 5463
 0.2
chr11_58777091_58777242 0.41 RP11-142C4.6
30408
 0.16
chr1_150584633_150584820 0.41 ENSG00000253047
 .
 11591
 0.1
chr7_6114490_6114641 0.41 ENSG00000264605
 .
 8171
 0.11
chr19_54881247_54881398 0.41 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 736
 0.51
chr2_193992778_193992929 0.41 TMEFF2
 transmembrane protein with EGF-like and two follistatin-like domains 2
 932418
 0.0
chr7_17039488_17039788 0.41 AGR3
 anterior gradient 3
 118027
 0.06
chr9_116280364_116280637 0.41 RGS3
 regulator of G-protein signaling 3
 950
 0.63
chr14_22747289_22747440 0.41 ENSG00000238634
 .
 136477
 0.04
chr1_84610970_84611403 0.40 PRKACB
 protein kinase, cAMP-dependent, catalytic, beta
 1232
 0.6
chr5_142985423_142985638 0.40 CTB-57H20.1
337
 0.92
chr4_27628366_27628517 0.40 ENSG00000222206
 .
 403392
 0.01
chr12_15136217_15136368 0.40 PDE6H
 phosphodiesterase 6H, cGMP-specific, cone, gamma
 10336
 0.18
chr1_112263594_112263745 0.40 FAM212B
 family with sequence similarity 212, member B
 18206
 0.15
chr15_52844361_52844512 0.40 ARPP19
 cAMP-regulated phosphoprotein, 19kDa
 5505
 0.2
chr9_70495582_70495733 0.40 CBWD5
 COBW domain containing 5
 5411
 0.29
chr1_236284065_236284436 0.40 GPR137B
 G protein-coupled receptor 137B
 21582
 0.19
chrX_118818753_118818904 0.40 SEPT6
 septin 6
 7964
 0.18
chr9_82185992_82186420 0.39 TLE4
 transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
 482
 0.9
chr14_90187580_90187856 0.39 ENSG00000200312
 .
 8863
 0.23
chr14_102291094_102291439 0.39 CTD-2017C7.1
14602
 0.14
chr17_33848477_33848647 0.39 RP11-1094M14.5
11273
 0.11
chr15_58624269_58624447 0.39 ALDH1A2
 aldehyde dehydrogenase 1 family, member A2
 52896
 0.15
chr9_69267993_69268163 0.39 CBWD6
 COBW domain containing 6
 5485
 0.22
chr6_2222723_2222882 0.39 GMDS
 GDP-mannose 4,6-dehydratase
 23124
 0.28
chr1_117058441_117058679 0.39 CD58
 CD58 molecule
 28652
 0.15
chr5_39074216_39074429 0.39 RICTOR
 RPTOR independent companion of MTOR, complex 2
 169
 0.97
chr8_98610443_98610623 0.39 MTDH
 metadherin
 45874
 0.18
chr11_61158553_61158704 0.39 TMEM216
 transmembrane protein 216
 531
 0.65
chr4_144312492_144312643 0.39 GAB1
 GRB2-associated binding protein 1
 96
 0.98
chr1_158983210_158983361 0.39 IFI16
 interferon, gamma-inducible protein 16
 1186
 0.5
chr7_33078848_33079779 0.38 NT5C3A
 5'-nucleotidase, cytosolic IIIA
 1208
 0.42
chrX_43609757_43609908 0.38 MAOA
 monoamine oxidase A
 94284
 0.09
chr13_41560147_41560327 0.38 ELF1
 E74-like factor 1 (ets domain transcription factor)
 3819
 0.25
chr2_192540821_192541028 0.38 NABP1
 nucleic acid binding protein 1
 1938
 0.47
chrX_13106517_13106711 0.38 FAM9C
 family with sequence similarity 9, member C
 43813
 0.18
chr1_161037877_161038104 0.38 ARHGAP30
 Rho GTPase activating protein 30
 1466
 0.19
chr4_156597609_156597760 0.38 GUCY1A3
 guanylate cyclase 1, soluble, alpha 3
 8869
 0.26
chr1_231112994_231113145 0.38 TTC13
 tetratricopeptide repeat domain 13
 1473
 0.28
chr10_129861850_129862130 0.38 PTPRE
 protein tyrosine phosphatase, receptor type, E
 16156
 0.26
chr1_112013416_112013602 0.38 C1orf162
 chromosome 1 open reading frame 162
 2905
 0.14
chrX_23969833_23969984 0.38 CXorf58
 chromosome X open reading frame 58
 41408
 0.14
chr14_77873229_77873401 0.37 FKSG61
9426
 0.11
chr12_89551363_89551514 0.37 ENSG00000238302
 .
 124624
 0.06
chr16_28504630_28504781 0.37 CLN3
 ceroid-lipofuscinosis, neuronal 3
 611
 0.54
chr1_92269176_92269391 0.37 ENSG00000239794
 .
 26348
 0.22
chr19_39160588_39160779 0.37 ACTN4
 actinin, alpha 4
 22305
 0.1
chr1_151431863_151432024 0.37 POGZ
 pogo transposable element with ZNF domain
 2
 0.96
chr5_88484775_88484926 0.37 MEF2C-AS1
 MEF2C antisense RNA 1
 223158
 0.02
chr14_70111468_70111619 0.37 KIAA0247
 KIAA0247
 33230
 0.18
chr16_68074331_68074482 0.37 DUS2
 dihydrouridine synthase 2
 2590
 0.14
chr1_167520324_167520695 0.36 CREG1
 cellular repressor of E1A-stimulated genes 1
 2495
 0.3
chr2_136876136_136876323 0.36 CXCR4
 chemokine (C-X-C motif) receptor 4
 494
 0.87
chr6_51167779_51167930 0.36 ENSG00000212532
 .
 161634
 0.04
chr3_15372748_15373059 0.36 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 1164
 0.41
chr1_22366515_22366832 0.36 CDC42
 cell division cycle 42
 12447
 0.11
chr5_75600050_75600201 0.36 RP11-466P24.6
7162
 0.3
chr7_35730972_35731297 0.36 HERPUD2
 HERPUD family member 2
 3042
 0.28
chr20_35580328_35580479 0.36 SAMHD1
 SAM domain and HD domain 1
 157
 0.96
chr10_114206747_114206976 0.36 VTI1A
 vesicle transport through interaction with t-SNAREs 1A
 155
 0.54
chr11_59949160_59949311 0.36 MS4A6A
 membrane-spanning 4-domains, subfamily A, member 6A
 96
 0.97
chr14_92332597_92332814 0.36 TC2N
 tandem C2 domains, nuclear
 1168
 0.51
chr6_36008402_36008553 0.35 MAPK14
 mitogen-activated protein kinase 14
 11611
 0.19
chr15_44101218_44101369 0.35 HYPK
 huntingtin interacting protein K
 8496
 0.08
chr8_27223967_27224118 0.35 PTK2B
 protein tyrosine kinase 2 beta
 14126
 0.22
chr3_156393455_156393974 0.35 TIPARP
 TCDD-inducible poly(ADP-ribose) polymerase
 356
 0.85
chr3_186237256_186237407 0.35 CRYGS
 crystallin, gamma S
 24909
 0.16
chr5_126147731_126147991 0.35 LMNB1
 lamin B1
 34980
 0.19
chr10_112632655_112633305 0.35 PDCD4-AS1
 PDCD4 antisense RNA 1
 989
 0.38
chr11_104576321_104576616 0.35 CASP12
 caspase 12 (gene/pseudogene)
 192673
 0.03
chr11_94661378_94661529 0.35 RP11-856F16.2
2767
 0.3
chr17_28085648_28085799 0.35 RP11-82O19.1
2398
 0.25
chr2_37192864_37193193 0.35 STRN
 striatin, calmodulin binding protein
 578
 0.73
chr13_46754554_46754849 0.35 LCP1
 lymphocyte cytosolic protein 1 (L-plastin)
 1758
 0.31
chr2_157197921_157198176 0.35 NR4A2
 nuclear receptor subfamily 4, group A, member 2
 812
 0.72
chr1_234735009_234735261 0.35 ENSG00000212144
 .
 6114
 0.19
chr19_7702650_7702852 0.35 STXBP2
 syntaxin binding protein 2
 738
 0.33
chr1_19804030_19804234 0.35 CAPZB
 capping protein (actin filament) muscle Z-line, beta
 6447
 0.18
chr11_88068800_88069370 0.35 CTSC
 cathepsin C
 1816
 0.49
chr20_24270294_24270445 0.35 ENSG00000200231
 .
 52478
 0.18
chr3_145437289_145437440 0.34 RP11-274H2.5
342102
 0.01
chr7_107530950_107531101 0.34 DLD
 dihydrolipoamide dehydrogenase
 390
 0.88
chr4_25865391_25865542 0.34 SEL1L3
 sel-1 suppressor of lin-12-like 3 (C. elegans)
 84
 0.98
chr10_7453140_7453326 0.34 SFMBT2
 Scm-like with four mbt domains 2
 215
 0.96
chr3_30646597_30646748 0.34 TGFBR2
 transforming growth factor, beta receptor II (70/80kDa)
 1322
 0.6
chr2_99345755_99346000 0.34 MGAT4A
 mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
 834
 0.68
chr6_159464766_159465080 0.34 TAGAP
 T-cell activation RhoGTPase activating protein
 1127
 0.51
chr2_238893215_238893433 0.34 UBE2F
 ubiquitin-conjugating enzyme E2F (putative)
 11587
 0.2
chr8_95972695_95972978 0.34 NDUFAF6
 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
 2600
 0.21
chr15_50557147_50557298 0.34 HDC
 histidine decarboxylase
 641
 0.66
chr11_104904746_104905919 0.34 CASP1
 caspase 1, apoptosis-related cysteine peptidase
 508
 0.77
chr9_125662893_125663901 0.34 RC3H2
 ring finger and CCCH-type domains 2
 3008
 0.16
chr7_73509063_73509569 0.34 LIMK1
 LIM domain kinase 1
 1907
 0.33
chr2_117455100_117455251 0.34 ENSG00000239185
 .
 442176
 0.01
chr5_148143102_148143253 0.34 ADRB2
 adrenoceptor beta 2, surface
 62979
 0.12
chr3_128899189_128899802 0.33 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 3247
 0.18
chr12_40012503_40012670 0.33 ABCD2
 ATP-binding cassette, sub-family D (ALD), member 2
 967
 0.63
chr1_51442241_51442392 0.33 CDKN2C
 cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
 6700
 0.22
chr3_151911560_151911983 0.33 MBNL1
 muscleblind-like splicing regulator 1
 74058
 0.11
chr12_131796680_131796831 0.33 ENSG00000212251
 .
 12459
 0.23
chr5_17282868_17283019 0.33 ENSG00000252908
 .
 42223
 0.15
chr1_27998753_27999101 0.33 IFI6
 interferon, alpha-inducible protein 6
 198
 0.89
chr8_117885462_117886204 0.33 RAD21
 RAD21 homolog (S. pombe)
 766
 0.36
chr6_36215434_36215585 0.33 PNPLA1
 patatin-like phospholipase domain containing 1
 4529
 0.21
chr7_135656834_135656985 0.33 MTPN
 myotrophin
 5155
 0.19
chr17_66031093_66031463 0.33 KPNA2
 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
 357
 0.87
chr1_226242002_226242153 0.33 H3F3A
 H3 histone, family 3A
 7475
 0.17
chr2_201987732_201987883 0.33 CFLAR
 CASP8 and FADD-like apoptosis regulator
 607
 0.65
chr18_46455022_46455234 0.33 SMAD7
 SMAD family member 7
 19747
 0.23
chr16_71935673_71935824 0.32 IST1
 increased sodium tolerance 1 homolog (yeast)
 6256
 0.13
chr8_41649611_41650018 0.32 ANK1
 ankyrin 1, erythrocytic
 5326
 0.2
chr6_119131761_119131953 0.32 MCM9
 minichromosome maintenance complex component 9
 18559
 0.24
chr19_40791807_40791974 0.32 AKT2
 v-akt murine thymoma viral oncogene homolog 2
 447
 0.68
chr17_77005019_77005688 0.32 CANT1
 calcium activated nucleotidase 1
 459
 0.76

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of ISX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010447 response to acidic pH(GO:0010447)
0.1 0.4 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.4 GO:0030011 maintenance of cell polarity(GO:0030011)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.1 0.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.1 0.5 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.1 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.1 0.2 GO:0002407 dendritic cell chemotaxis(GO:0002407) dendritic cell migration(GO:0036336)
0.1 0.4 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0045116 protein neddylation(GO:0045116)
0.1 0.3 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.3 GO:0002513 tolerance induction to self antigen(GO:0002513)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.2 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.6 GO:0015671 oxygen transport(GO:0015671)
0.1 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.2 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 0.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 0.3 GO:0044380 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1 0.2 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.1 0.2 GO:0034723 DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.2 GO:1903224 endodermal cell fate specification(GO:0001714) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.1 0.1 GO:0046398 UDP-glucuronate metabolic process(GO:0046398)
0.1 0.2 GO:0055064 cellular chloride ion homeostasis(GO:0030644) chloride ion homeostasis(GO:0055064)
0.1 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.1 GO:0032632 interleukin-3 production(GO:0032632)
0.1 0.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.1 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0001821 histamine secretion(GO:0001821)
0.1 0.1 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.1 0.2 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.2 GO:0045767 obsolete regulation of anti-apoptosis(GO:0045767)
0.1 0.3 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.2 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.1 0.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.1 GO:0060972 left/right pattern formation(GO:0060972)
0.1 0.1 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.1 0.2 GO:0002507 tolerance induction(GO:0002507)
0.0 0.4 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.2 GO:0045056 transcytosis(GO:0045056)
0.0 0.2 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.3 GO:0070265 necrotic cell death(GO:0070265)
0.0 0.0 GO:0046645 regulation of gamma-delta T cell activation(GO:0046643) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.2 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.0 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0034728 nucleosome organization(GO:0034728)
0.0 0.1 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.1 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.1 GO:1901339 activation of store-operated calcium channel activity(GO:0032237) regulation of store-operated calcium channel activity(GO:1901339) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.3 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.3 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.4 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.1 GO:0043312 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.0 0.1 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.2 GO:0051299 centrosome separation(GO:0051299)
0.0 0.8 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.2 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:0032148 activation of protein kinase B activity(GO:0032148)
0.0 0.1 GO:0003161 cardiac conduction system development(GO:0003161)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0072577 endothelial cell apoptotic process(GO:0072577) epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035) regulation of endothelial cell apoptotic process(GO:2000351)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:0090114 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.1 GO:0046101 hypoxanthine biosynthetic process(GO:0046101)
0.0 1.5 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.5 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0061384 heart trabecula formation(GO:0060347) heart trabecula morphogenesis(GO:0061384)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0032650 regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 0.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.1 GO:0070234 positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245) positive regulation of leukocyte apoptotic process(GO:2000108)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.7 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.2 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.0 GO:0032959 inositol trisphosphate biosynthetic process(GO:0032959)
0.0 0.2 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.5 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:1903312 negative regulation of mRNA processing(GO:0050686) negative regulation of mRNA metabolic process(GO:1903312)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.0 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.4 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.0 GO:0060413 atrial septum development(GO:0003283) atrial septum morphogenesis(GO:0060413)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0 0.1 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354)
0.0 0.1 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.2 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.0 GO:0048263 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 0.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.0 0.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.0 0.1 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.4 GO:1903038 negative regulation of T cell activation(GO:0050868) negative regulation of leukocyte cell-cell adhesion(GO:1903038)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.0 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.0 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0090322 regulation of superoxide metabolic process(GO:0090322)
0.0 0.0 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.0 0.1 GO:0045003 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0 0.0 GO:0060323 head morphogenesis(GO:0060323)
0.0 0.1 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.3 GO:0006024 glycosaminoglycan biosynthetic process(GO:0006024)
0.0 0.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 0.1 GO:0034625 fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0 0.1 GO:0045217 cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0009186 deoxyribonucleoside diphosphate metabolic process(GO:0009186)
0.0 0.3 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.0 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518) negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0043486 histone exchange(GO:0043486)
0.0 0.0 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0052510 modulation by symbiont of host defense response(GO:0052031) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553)
0.0 0.0 GO:0008216 spermidine metabolic process(GO:0008216)
0.0 0.2 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.0 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.0 GO:0048670 collateral sprouting(GO:0048668) regulation of collateral sprouting(GO:0048670)
0.0 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055) negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.1 GO:0046337 phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.3 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.2 GO:0045806 negative regulation of endocytosis(GO:0045806)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.0 GO:0001820 serotonin secretion(GO:0001820)
0.0 0.3 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.0 GO:1901419 regulation of response to alcohol(GO:1901419)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0033003 regulation of mast cell activation(GO:0033003)
0.0 0.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621) regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.1 GO:0008634 obsolete negative regulation of survival gene product expression(GO:0008634)
0.0 0.2 GO:0032011 ARF protein signal transduction(GO:0032011)
0.0 0.1 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.0 0.1 GO:0045576 mast cell activation(GO:0045576)
0.0 0.1 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.0 GO:0070254 mucus secretion(GO:0070254)
0.0 0.0 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.0 GO:0003179 heart valve development(GO:0003170) heart valve morphogenesis(GO:0003179)
0.0 0.2 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0034123 positive regulation of toll-like receptor signaling pathway(GO:0034123)
0.0 0.6 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:0000288)
0.0 0.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.0 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.0 GO:0034444 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161)
0.0 0.1 GO:0007128 meiotic prophase I(GO:0007128)
0.0 0.1 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.2 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.0 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005) negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.0 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:0042094 interleukin-2 biosynthetic process(GO:0042094)
0.0 0.0 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.0 0.0 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0 0.1 GO:0009309 amine biosynthetic process(GO:0009309)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 2.1 GO:0016568 chromatin modification(GO:0016568)
0.0 0.0 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.0 GO:0045990 carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:0045329 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0060065 uterus development(GO:0060065)
0.0 0.2 GO:0071260 cellular response to mechanical stimulus(GO:0071260)
0.0 0.0 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.0 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.0 0.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.0 0.0 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.0 GO:0060896 neural plate pattern specification(GO:0060896)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.2 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.0 GO:0032490 detection of molecule of bacterial origin(GO:0032490)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042629 mast cell granule(GO:0042629)
0.2 0.7 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.5 GO:0071778 obsolete WINAC complex(GO:0071778)
0.1 1.0 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0072487 MSL complex(GO:0072487)
0.1 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.3 GO:0070820 tertiary granule(GO:0070820)
0.1 0.3 GO:0017059 palmitoyltransferase complex(GO:0002178) serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 0.2 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0043218 compact myelin(GO:0043218)
0.1 0.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0070822 Sin3 complex(GO:0016580) Sin3-type complex(GO:0070822)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.9 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.0 GO:0031312 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of organelle membrane(GO:0031312) extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0016585 obsolete chromatin remodeling complex(GO:0016585)
0.0 2.2 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
0.0 0.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.0 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.0 GO:0070188 obsolete Stn1-Ten1 complex(GO:0070188)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 1.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 0.0 GO:0030312 external encapsulating structure(GO:0030312) external encapsulating structure part(GO:0044462)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.1 GO:0032279 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0031143 pseudopodium(GO:0031143)
0.0 0.3 GO:0005680 nuclear ubiquitin ligase complex(GO:0000152) anaphase-promoting complex(GO:0005680)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.4 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.6 GO:0005769 early endosome(GO:0005769)
0.0 0.0 GO:0071547 piP-body(GO:0071547)
0.0 0.8 GO:0000785 chromatin(GO:0000785)
0.0 0.1 GO:0043209 myelin sheath(GO:0043209)
0.0 0.0 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.0 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.3 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 0.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.6 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 0.2 GO:0032357 single guanine insertion binding(GO:0032142) oxidized DNA binding(GO:0032356) oxidized purine DNA binding(GO:0032357)
0.1 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.1 GO:0045159 myosin II binding(GO:0045159)
0.1 2.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.3 GO:0001846 opsonin binding(GO:0001846)
0.1 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0046625 sphingolipid binding(GO:0046625)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0098847 single-stranded telomeric DNA binding(GO:0043047) sequence-specific single stranded DNA binding(GO:0098847)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:1990782 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0004448 isocitrate dehydrogenase activity(GO:0004448)
0.0 0.1 GO:0030507 spectrin binding(GO:0030507)
0.0 1.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.0 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.1 GO:1901474 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.4 GO:0008186 RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.0 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.9 GO:0004221 obsolete ubiquitin thiolesterase activity(GO:0004221)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.1 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 0.0 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.0 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:0016417 S-acyltransferase activity(GO:0016417)
0.0 0.0 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.0 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor(GO:0016653)
0.0 0.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0035197 siRNA binding(GO:0035197)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.0 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.0 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0004601 peroxidase activity(GO:0004601) oxidoreductase activity, acting on peroxide as acceptor(GO:0016684)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.6 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.9 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.2 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 1.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.1 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.1 0.9 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 0.1 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 0.9 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.1 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.2 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.0 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 0.4 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.1 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.0 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME APOPTOSIS Genes involved in Apoptosis
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.2 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.9 REACTOME INTERFERON SIGNALING Genes involved in Interferon Signaling
0.0 0.0 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions