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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for JDP2

Z-value: 1.36

Motif logo

Transcription factors associated with JDP2

Gene Symbol	Gene ID	Gene Info
JDP2 Ensembl NCBI GeneCards UniProt	ENSG00000140044.8	JDP2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
JDP2	chr14_75925878_75926029	27116	0.157778	-0.75	1.9e-02	Click!
JDP2	chr14_75925653_75925804	26891	0.158277	-0.71	3.2e-02	Click!
JDP2	chr14_75920844_75920995	22082	0.168556	-0.65	5.8e-02	Click!
JDP2	chr14_75919897_75920096	21159	0.170434	0.49	1.8e-01	Click!
JDP2	chr14_75923265_75923416	24503	0.163477	-0.44	2.4e-01	Click!

Activity of the JDP2 motif across conditions

Conditions sorted by the z-value of the JDP2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_80603632_80603783	0.69	RP11-525K10.3		6675	0.18
chr15_75943747_75944181	0.67	SNX33	sorting nexin 33	1867	0.18
chr3_93878024_93878443	0.67	ENSG00000253062	.	60823	0.12
chr12_113859774_113860410	0.59	SDSL	serine dehydratase-like	50	0.97
chr18_29929931_29930163	0.59	RP11-344B2.2		62647	0.1
chr6_82854353_82854866	0.54	ENSG00000223044	.	65548	0.14
chr9_124991302_124991453	0.54	LHX6	LIM homeobox 6	157	0.94
chr17_4762471_4762622	0.53	ENSG00000263599	.	16375	0.08
chr12_3277666_3277860	0.53	TSPAN9-IT1	TSPAN9 intronic transcript 1 (non-protein coding)	18800	0.21
chr6_44424385_44424803	0.52	ENSG00000266619	.	21216	0.17
chr13_59357512_59357663	0.52	ENSG00000222733	.	255702	0.02
chr4_158941489_158941966	0.51	FAM198B	family with sequence similarity 198, member B	139106	0.05
chr1_85763681_85764097	0.51	ENSG00000264380	.	13596	0.14
chrX_48917537_48917688	0.51	CCDC120	coiled-coil domain containing 120	1066	0.3
chr4_183047320_183047598	0.51	AC108142.1		17470	0.17
chr1_214649424_214649729	0.50	PTPN14	protein tyrosine phosphatase, non-receptor type 14	11430	0.29
chr11_11589938_11590089	0.50	RP11-483L5.1		1618	0.47
chr6_72595878_72596126	0.50	RIMS1	regulating synaptic membrane exocytosis 1	404	0.92
chr6_14001615_14001982	0.50	RNF182	ring finger protein 182	76374	0.11
chr9_86916681_86916945	0.49	RP11-380F14.2		23679	0.22
chr5_14268280_14268580	0.48	TRIO	trio Rho guanine nucleotide exchange factor	22656	0.28
chr5_42772787_42772984	0.48	CCDC152	coiled-coil domain containing 152	15965	0.2
chr7_110026237_110026388	0.48	AC073326.3		339569	0.01
chr11_62308687_62309106	0.48	RP11-864I4.3		4112	0.1
chr11_128778623_128778851	0.48	KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	2342	0.24
chr9_100465936_100466445	0.47	ENSG00000266608	.	3674	0.21
chr15_71126267_71126418	0.46	RP11-138H8.6		15767	0.15
chr6_150346440_150346821	0.46	RAET1L	retinoic acid early transcript 1L	23	0.97
chr2_27502961_27503177	0.45	TRIM54	tripartite motif containing 54	2191	0.15
chr9_122573363_122573648	0.45	RP11-295D22.1	Uncharacterized protein	315852	0.01
chr1_112135126_112135664	0.45	RAP1A	RAP1A, member of RAS oncogene family	27004	0.14
chr16_3692877_3693028	0.45	DNASE1	deoxyribonuclease I	13	0.97
chr8_74473490_74473704	0.45	STAU2	staufen double-stranded RNA binding protein 2	21468	0.27
chr17_3694838_3694989	0.44	ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	9624	0.15
chr8_24867437_24867792	0.44	CTD-2168K21.2		53479	0.14
chr2_91845042_91845193	0.44	AC027612.6		1588	0.43
chr8_105677603_105677754	0.44	RP11-127H5.1	Uncharacterized protein	74717	0.1
chr11_12065337_12065964	0.44	DKK3	dickkopf WNT signaling pathway inhibitor 3	34334	0.19
chr1_86316102_86316253	0.43	ENSG00000201620	.	33304	0.23
chr1_221209086_221209419	0.43	HLX	H2.0-like homeobox	154668	0.04
chr7_24988449_24988600	0.43	OSBPL3	oxysterol binding protein-like 3	30812	0.21
chr19_48793598_48793806	0.43	ZNF114	zinc finger protein 114	18822	0.1
chr4_139146799_139146992	0.43	SLC7A11	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	16608	0.27
chr1_115732540_115732691	0.43	RP4-663N10.1		93040	0.08
chr2_100635044_100635528	0.43	AFF3	AF4/FMR2 family, member 3	85706	0.09
chr16_12121143_12121294	0.42	SNX29	sorting nexin 29	24837	0.12
chr19_49071767_49072143	0.42	SULT2B1	sulfotransferase family, cytosolic, 2B, member 1	6842	0.11
chr11_133827302_133827588	0.42	IGSF9B	immunoglobulin superfamily, member 9B	565	0.52
chr19_7456170_7456333	0.42	CTB-133G6.2		3674	0.16
chr4_177192376_177192684	0.41	ASB5	ankyrin repeat and SOCS box containing 5	2157	0.35
chr10_22717226_22717377	0.41	RP11-301N24.3		67200	0.1
chrX_133147131_133147282	0.41	GPC3	glypican 3	27284	0.21
chr7_22473101_22473341	0.41	ENSG00000263927	.	53598	0.13
chr2_28672824_28673107	0.41	PLB1	phospholipase B1	7047	0.22
chr3_71031910_71032144	0.41	FOXP1	forkhead box P1	82050	0.1
chr11_132910564_132910715	0.41	OPCML	opioid binding protein/cell adhesion molecule-like	96976	0.09
chr1_149911166_149911509	0.40	MTMR11	myotubularin related protein 11	2546	0.15
chr17_2869143_2869294	0.40	CTD-3060P21.1		29	0.98
chr10_62734565_62734716	0.40	RHOBTB1	Rho-related BTB domain containing 1	26558	0.24
chr3_42138838_42138989	0.40	TRAK1	trafficking protein, kinesin binding 1	6351	0.29
chr1_63156195_63156408	0.40	RP11-230B22.1		2148	0.29
chr17_8976590_8976741	0.40	NTN1	netrin 1	51045	0.15
chr17_6458496_6458984	0.39	PITPNM3	PITPNM family member 3	1040	0.49
chr18_26736738_26736889	0.39	ENSG00000212085	.	39679	0.19
chr3_55236478_55236629	0.39	LRTM1	leucine-rich repeats and transmembrane domains 1	235438	0.02
chr11_125497290_125497441	0.39	CHEK1	checkpoint kinase 1	722	0.57
chr18_55863472_55863729	0.39	RP11-718I15.1		672	0.47
chr8_62621050_62621416	0.39	ASPH	aspartate beta-hydroxylase	5851	0.24
chr18_47447340_47447629	0.39	MYO5B	myosin VB	16441	0.16
chr9_21677527_21678485	0.38	ENSG00000244230	.	21307	0.21
chr16_29302545_29302873	0.38	RP11-231C14.6		20962	0.17
chr21_33893367_33893849	0.38	ENSG00000252045	.	17001	0.16
chr1_76231453_76231604	0.38	RABGGTB	Rab geranylgeranyltransferase, beta subunit	20351	0.11
chr16_14051400_14051742	0.38	CTD-2135D7.2		22079	0.22
chr7_41511992_41512216	0.38	INHBA-AS1	INHBA antisense RNA 1	221410	0.02
chr16_88298914_88299157	0.37	ZNF469	zinc finger protein 469	194844	0.02
chr3_143550249_143550400	0.37	SLC9A9	solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9	16976	0.29
chr1_201818774_201819040	0.37	IPO9-AS1	IPO9 antisense RNA 1	20220	0.11
chr18_47419130_47419281	0.37	MYO5B	myosin VB	10000	0.17
chr9_140089237_140089388	0.37	TPRN	taperin	5245	0.06
chrX_46838635_46838911	0.37	JADE3	jade family PHD finger 3	66542	0.09
chr12_52835040_52835191	0.37	KRT75	keratin 75	6806	0.1
chr6_37105912_37106091	0.37	PIM1	pim-1 oncogene	31978	0.15
chr6_150218431_150218911	0.37	RAET1E	retinoic acid early transcript 1E	567	0.64
chr6_12546181_12546332	0.36	ENSG00000223321	.	139243	0.05
chr2_60743182_60743762	0.36	AC009970.1		20651	0.21
chr8_128911768_128911919	0.36	TMEM75	transmembrane protein 75	48748	0.14
chr9_91793130_91793737	0.36	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	249	0.95
chr15_59560646_59560813	0.35	RP11-429D19.1		2632	0.22
chr12_120242288_120242514	0.35	CIT	citron (rho-interacting, serine/threonine kinase 21)	1214	0.56
chr11_120211307_120211458	0.35	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	3436	0.23
chr4_122612105_122612382	0.35	ANXA5	annexin A5	5874	0.26
chr6_158034126_158034277	0.35	ZDHHC14	zinc finger, DHHC-type containing 14	20160	0.25
chr1_205263814_205264026	0.35	NUAK2	NUAK family, SNF1-like kinase, 2	26963	0.14
chr1_115842859_115843157	0.34	RP4-663N10.1		17353	0.23
chr9_132595482_132595633	0.34	C9orf78	chromosome 9 open reading frame 78	1997	0.23
chr10_35927790_35928179	0.34	ENSG00000264780	.	2196	0.26
chr14_53301814_53302501	0.34	FERMT2	fermitin family member 2	29082	0.15
chr14_65473243_65473394	0.34	RP11-840I19.5		2833	0.17
chr1_233430570_233431212	0.34	PCNXL2	pecanex-like 2 (Drosophila)	568	0.83
chr6_138914677_138915087	0.34	NHSL1	NHS-like 1	21205	0.24
chr12_91503113_91503264	0.34	LUM	lumican	2420	0.34
chr20_56347674_56347957	0.34	PMEPA1	prostate transmembrane protein, androgen induced 1	61274	0.13
chr9_139120133_139120505	0.34	QSOX2	quiescin Q6 sulfhydryl oxidase 2	3596	0.22
chr7_98048096_98048428	0.34	BAIAP2L1	BAI1-associated protein 2-like 1	17882	0.23
chr10_54203606_54203757	0.34	RP11-556E13.1		117184	0.06
chr2_224428342_224428624	0.33	SCG2	secretogranin II	38519	0.23
chr8_27471536_27471788	0.33	CLU	clusterin	98	0.97
chr3_194494197_194494348	0.33	FAM43A	family with sequence similarity 43, member A	87650	0.07
chr20_19973893_19974157	0.33	NAA20	N(alpha)-acetyltransferase 20, NatB catalytic subunit	23735	0.19
chr5_42641311_42641462	0.33	GHR	growth hormone receptor	75428	0.11
chr14_96312809_96312960	0.33	ENSG00000263357	.	5043	0.29
chr5_17025139_17025290	0.33	BASP1	brain abundant, membrane attached signal protein 1	40493	0.16
chr1_28431643_28431939	0.33	EYA3	eyes absent homolog 3 (Drosophila)	16584	0.13
chr2_201630913_201631184	0.33	ENSG00000201737	.	9259	0.15
chr1_37936969_37937609	0.33	LINC01137	long intergenic non-protein coding RNA 1137	2723	0.2
chr1_209212803_209213215	0.32	ENSG00000230937	.	392469	0.01
chr5_119741046_119741197	0.32	PRR16	proline rich 16	58852	0.15
chr6_139870784_139870935	0.32	CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	175102	0.03
chr1_117542347_117542498	0.32	CD101	CD101 molecule	1960	0.31
chr15_70877228_70877484	0.32	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	117264	0.06
chr12_132268438_132268589	0.32	ENSG00000200516	.	17466	0.16
chr6_116708231_116708568	0.32	DSE	dermatan sulfate epimerase	16289	0.18
chr5_60524633_60524784	0.32	SMIM15	small integral membrane protein 15	66407	0.11
chr12_69894541_69894847	0.32	FRS2	fibroblast growth factor receptor substrate 2	29909	0.17
chr20_16800308_16800459	0.32	OTOR	otoraplin	71380	0.11
chr19_30159907_30160058	0.32	PLEKHF1	pleckstrin homology domain containing, family F (with FYVE domain) member 1	2201	0.36
chr4_148703526_148703701	0.32	ENSG00000264274	.	133	0.96
chr4_85859566_85859717	0.32	WDFY3	WD repeat and FYVE domain containing 3	27862	0.22
chr5_66311217_66311678	0.32	MAST4	microtubule associated serine/threonine kinase family member 4	10964	0.24
chr8_41628467_41628645	0.32	ANK1	ankyrin 1, erythrocytic	26584	0.16
chr4_27985809_27985960	0.32	RP11-180C1.1	Uncharacterized protein	418439	0.01
chr19_18385706_18385857	0.32	KIAA1683	KIAA1683	462	0.67
chr12_115813083_115813371	0.31	RP11-116D17.1	HCG2038717; Uncharacterized protein	12410	0.32
chr4_74308058_74308209	0.31	AFP	alpha-fetoprotein	6169	0.22
chr6_112145118_112145500	0.31	FYN	FYN oncogene related to SRC, FGR, YES	4028	0.33
chr6_4352330_4352530	0.31	ENSG00000201185	.	75767	0.11
chr1_147148877_147149210	0.31	ACP6	acid phosphatase 6, lysophosphatidic	6425	0.22
chr9_29039310_29039461	0.30	ENSG00000215939	.	150432	0.05
chr2_234883363_234883514	0.30	TRPM8	transient receptor potential cation channel, subfamily M, member 8	8176	0.21
chr15_39579783_39579934	0.30	RP11-624L4.1		13774	0.25
chr2_218784709_218784860	0.30	TNS1	tensin 1	148	0.97
chr9_130717791_130717942	0.30	FAM102A	family with sequence similarity 102, member A	4865	0.11
chr5_146783684_146783835	0.30	CTB-108O6.2		2436	0.31
chr3_14042592_14042743	0.30	TPRXL	tetra-peptide repeat homeobox-like	1257	0.54
chr17_15301686_15301923	0.30	ENSG00000239888	.	9897	0.2
chr3_64174748_64175187	0.30	PRICKLE2-AS3	PRICKLE2 antisense RNA 3	1747	0.38
chr5_18762110_18762261	0.29	ENSG00000238674	.	81821	0.12
chr19_39853441_39853592	0.29	SAMD4B	sterile alpha motif domain containing 4B	6060	0.09
chrX_34828537_34828688	0.29	FAM47B	family with sequence similarity 47, member B	132301	0.06
chr12_75283505_75283691	0.29	RP11-81K13.1		131151	0.06
chr4_187854005_187854180	0.29	ENSG00000252382	.	75482	0.12
chr11_13481327_13481478	0.29	BTBD10	BTB (POZ) domain containing 10	3326	0.3
chr7_22898137_22898380	0.29	ENSG00000221740	.	2026	0.38
chr7_2882805_2883043	0.29	GNA12	guanine nucleotide binding protein (G protein) alpha 12	726	0.76
chr11_7986571_7986722	0.29	NLRP10	NLR family, pyrin domain containing 10	327	0.83
chr17_48716193_48716344	0.29	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	4050	0.14
chr8_48343964_48344189	0.29	SPIDR	scaffolding protein involved in DNA repair	8887	0.29
chr14_88336299_88336450	0.28	GALC	galactosylceramidase	122808	0.06
chr10_3270107_3270258	0.28	PITRM1	pitrilysin metallopeptidase 1	55179	0.15
chr8_144653425_144654110	0.28	MROH6	maestro heat-like repeat family member 6	1151	0.21
chr4_152462150_152462592	0.28	FAM160A1	family with sequence similarity 160, member A1	8207	0.21
chr3_197044241_197044392	0.28	DLG1	discs, large homolog 1 (Drosophila)	18145	0.15
chr3_192536808_192537029	0.28	FGF12	fibroblast growth factor 12	51365	0.16
chr18_26737213_26737364	0.28	ENSG00000212085	.	39204	0.19
chr15_93168974_93169125	0.28	FAM174B	family with sequence similarity 174, member B	13425	0.22
chr6_3209808_3210009	0.28	TUBB2B	tubulin, beta 2B class IIb	18061	0.15
chr12_107908945_107909258	0.28	ENSG00000222302	.	28689	0.2
chr20_20432923_20433275	0.28	RALGAPA2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	60145	0.13
chr19_58837119_58837270	0.28	ZSCAN22	zinc finger and SCAN domain containing 22	1191	0.24
chr16_12434298_12434449	0.27	SNX29	sorting nexin 29	15737	0.17
chr17_77022963_77023114	0.27	C1QTNF1-AS1	C1QTNF1 antisense RNA 1	645	0.56
chr2_205660028_205660179	0.27	PARD3B	par-3 family cell polarity regulator beta	249380	0.02
chr22_19564292_19564522	0.27	CLDN5	claudin 5	49339	0.11
chr5_92414302_92414540	0.27	ENSG00000237187	.	343698	0.01
chr16_75353982_75354222	0.27	RP11-252K23.1		4844	0.17
chr14_70059974_70060446	0.27	KIAA0247	KIAA0247	18103	0.2
chr18_60434749_60434900	0.27	ENSG00000206746	.	36259	0.15
chr3_138153080_138153961	0.27	ESYT3	extended synaptotagmin-like protein 3	53	0.98
chr7_33914000_33914151	0.27	BMPER	BMP binding endothelial regulator	30448	0.24
chr3_170979334_170979485	0.27	TNIK	TRAF2 and NCK interacting kinase	35909	0.22
chr15_85948340_85948491	0.27	ENSG00000251891	.	15300	0.2
chr4_159992618_159992885	0.27	ENSG00000206978	.	7201	0.18
chr6_159271096_159271505	0.27	C6orf99	chromosome 6 open reading frame 99	19671	0.16
chr1_109740919_109741171	0.27	ENSG00000238310	.	9425	0.15
chr6_138571879_138572276	0.27	PBOV1	prostate and breast cancer overexpressed 1	32450	0.2
chr15_74093075_74093391	0.26	C15orf59	chromosome 15 open reading frame 59	48145	0.12
chr7_38885898_38886049	0.26	VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	15027	0.28
chr4_48728692_48728843	0.26	FRYL	FRY-like	45579	0.16
chr9_75771174_75771814	0.26	ANXA1	annexin A1	1076	0.66
chr17_73680522_73680673	0.26	RP11-474I11.7		282	0.82
chr20_25290950_25291163	0.26	ABHD12	abhydrolase domain containing 12	922	0.6
chr3_197581656_197581918	0.26	LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	6915	0.18
chr17_16420060_16420464	0.26	FAM211A	family with sequence similarity 211, member A	24795	0.14
chr22_40928059_40928879	0.26	MKL1	megakaryoblastic leukemia (translocation) 1	1346	0.4
chr19_45414386_45414667	0.26	APOC1	apolipoprotein C-I	2978	0.11
chr5_141700925_141701122	0.26	SPRY4	sprouty homolog 4 (Drosophila)	2724	0.3
chr19_29521126_29521277	0.26	ENSG00000252272	.	28624	0.24
chr6_18488896_18489181	0.26	ENSG00000207775	.	82977	0.09
chr12_120637695_120638021	0.26	RPLP0	ribosomal protein, large, P0	760	0.43

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of JDP2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0021853	interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1	0.3	GO:0051788	response to misfolded protein(GO:0051788)
0.1	0.4	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.3	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.1	0.2	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.1	0.2	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.2	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.0	0.1	GO:0016081	synaptic vesicle docking(GO:0016081)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.2	GO:0032277	negative regulation of gonadotropin secretion(GO:0032277)
0.0	0.1	GO:0060831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:0060831)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.3	GO:0060122	inner ear receptor stereocilium organization(GO:0060122)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.0	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.0	GO:1903726	negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.2	GO:0021952	central nervous system projection neuron axonogenesis(GO:0021952)
0.0	0.4	GO:0016079	synaptic vesicle exocytosis(GO:0016079)
0.0	0.1	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0042109	lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646) phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0072111	cell proliferation involved in kidney development(GO:0072111)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0	0.0	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.0	GO:0070309	lens fiber cell morphogenesis(GO:0070309)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0	0.1	GO:0008356	asymmetric cell division(GO:0008356)
0.0	0.1	GO:2000008	regulation of protein localization to cell surface(GO:2000008)
0.0	0.4	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.3	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.0	GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.0	0.0	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.4	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0060294	regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356) cilium movement involved in cell motility(GO:0060294) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0	0.1	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0	0.1	GO:0048245	eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.0	0.1	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.0	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.0	GO:0071294	cellular response to zinc ion(GO:0071294)
0.0	0.1	GO:0018119	protein nitrosylation(GO:0017014) peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.5	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.1	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:0010842	retina layer formation(GO:0010842)
0.0	0.0	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0042494	detection of bacterial lipoprotein(GO:0042494) detection of bacterial lipopeptide(GO:0070340)
0.0	0.1	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.0	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.0	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.4	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0051927	obsolete negative regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051927)
0.0	0.0	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.0	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.7	GO:0019882	antigen processing and presentation(GO:0019882)
0.0	0.0	GO:0031579	membrane raft organization(GO:0031579)
0.0	0.0	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.0	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.0	0.0	GO:0032966	negative regulation of collagen biosynthetic process(GO:0032966)
0.0	0.0	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0060913	cardiac cell fate determination(GO:0060913)
0.0	0.1	GO:0043278	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.1	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.2	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.7	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0032449	CBM complex(GO:0032449)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0002142	stereocilia coupling link(GO:0002139) stereocilia ankle link(GO:0002141) stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.5	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.2	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.1	0.2	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0008109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0	0.1	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0	0.2	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.5	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0046980	tapasin binding(GO:0046980)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.1	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0	0.1	GO:0005350	pyrimidine nucleobase transmembrane transporter activity(GO:0005350)
0.0	0.2	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.1	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.2	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.4	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.1	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.3	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.0	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.0	GO:0017060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0	0.1	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.0	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.0	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.0	GO:0000404	heteroduplex DNA loop binding(GO:0000404)
0.0	0.0	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0004936	alpha-adrenergic receptor activity(GO:0004936) alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.3	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.6	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.1	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.4	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.1	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS	Genes involved in Activation of NMDA receptor upon glutamate binding and postsynaptic events