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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for JUND

Z-value: 1.73

Motif logo

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Transcription factors associated with JUND

Gene Symbol Gene ID Gene Info
JUND
ENSG00000130522.4 JunD proto-oncogene, AP-1 transcription factor subunit

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr19_18388821_18388972JUND28430.1317270.481.9e-01Click!
chr19_18389064_18389254JUND25800.1404320.393.0e-01Click!
chr19_18389866_18390017JUND17980.1871390.196.2e-01Click!
chr19_18391872_18392200JUND2970.725285-0.186.4e-01Click!
chr19_18390478_18391041JUND9800.3411340.137.4e-01Click!

Activity of the JUND motif across conditions

Conditions sorted by the z-value of the JUND motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr17_33373915_33374211 0.80 RFFL
 ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
 4693
 0.13
chr5_35857058_35857643 0.74 IL7R
 interleukin 7 receptor
 356
 0.89
chr11_118794237_118794443 0.73 BCL9L
 B-cell CLL/lymphoma 9-like
 4727
 0.09
chr14_22971834_22972057 0.73 TRAJ51
 T cell receptor alpha joining 51 (pseudogene)
 15774
 0.09
chr4_122164507_122165136 0.71 TNIP3
 TNFAIP3 interacting protein 3
 16200
 0.22
chr18_9117310_9117583 0.69 RP11-143J12.3
1571
 0.34
chr4_143325352_143326244 0.68 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 26614
 0.28
chr6_139852295_139852446 0.65 CITED2
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
 156613
 0.04
chr5_156616289_156616440 0.64 ITK
 IL2-inducible T-cell kinase
 8527
 0.13
chr5_151907362_151907513 0.64 NMUR2
 neuromedin U receptor 2
 122597
 0.07
chr1_160489868_160490211 0.62 SLAMF6
 SLAM family member 6
 2993
 0.18
chr1_160767367_160767518 0.61 LY9
 lymphocyte antigen 9
 1465
 0.39
chr2_231789411_231789754 0.60 GPR55
 G protein-coupled receptor 55
 359
 0.85
chr12_92172716_92172989 0.59 C12orf79
 chromosome 12 open reading frame 79
 357945
 0.01
chr22_31335429_31335580 0.59 MORC2
 MORC family CW-type zinc finger 2
 6623
 0.16
chr11_128376572_128377141 0.58 ETS1
 v-ets avian erythroblastosis virus E26 oncogene homolog 1
 1567
 0.47
chr1_117297247_117297398 0.58 CD2
 CD2 molecule
 233
 0.94
chr9_73027094_73027481 0.57 KLF9
 Kruppel-like factor 9
 2253
 0.41
chr12_21606326_21606605 0.56 PYROXD1
 pyridine nucleotide-disulphide oxidoreductase domain 1
 15616
 0.17
chr4_151540397_151540583 0.56 ENSG00000221235
 .
 20528
 0.2
chr6_90993958_90994705 0.55 BACH2
 BTB and CNC homology 1, basic leucine zipper transcription factor 2
 12130
 0.24
chr12_51418457_51418700 0.55 SLC11A2
 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
 48
 0.96
chr1_12509705_12509856 0.54 VPS13D
 vacuolar protein sorting 13 homolog D (S. cerevisiae)
 15215
 0.22
chr1_154299291_154299442 0.54 ATP8B2
 ATPase, aminophospholipid transporter, class I, type 8B, member 2
 910
 0.38
chr22_37545294_37545803 0.53 IL2RB
 interleukin 2 receptor, beta
 482
 0.7
chr18_7958694_7958932 0.53 PTPRM
 protein tyrosine phosphatase, receptor type, M
 11861
 0.23
chr4_143477803_143478104 0.53 INPP4B
 inositol polyphosphate-4-phosphatase, type II, 105kDa
 3869
 0.39
chr9_130732789_130732970 0.53 FAM102A
 family with sequence similarity 102, member A
 9913
 0.11
chr3_179372008_179372371 0.53 USP13
 ubiquitin specific peptidase 13 (isopeptidase T-3)
 708
 0.65
chr2_223654006_223654270 0.53 ACSL3
 acyl-CoA synthetase long-chain family member 3
 71514
 0.1
chr12_45625038_45625189 0.52 ANO6
 anoctamin 6
 15210
 0.28
chr4_26024061_26024293 0.51 SMIM20
 small integral membrane protein 20
 108246
 0.07
chr5_52336982_52337335 0.51 CTD-2366F13.2
48140
 0.12
chr12_96592768_96592919 0.51 ELK3
 ELK3, ETS-domain protein (SRF accessory protein 2)
 4451
 0.24
chr20_3913213_3913723 0.51 ENSG00000199024
 .
 15327
 0.15
chr18_3459636_3459787 0.50 TGIF1
 TGFB-induced factor homeobox 1
 4299
 0.25
chr20_48510567_48510837 0.50 SPATA2
 spermatogenesis associated 2
 19574
 0.13
chr18_9118459_9118745 0.50 RP11-143J12.3
2727
 0.22
chr21_15906632_15906783 0.50 SAMSN1
 SAM domain, SH3 domain and nuclear localization signals 1
 11955
 0.25
chr3_187520878_187521148 0.49 BCL6
 B-cell CLL/lymphoma 6
 57498
 0.14
chr6_42391109_42391260 0.49 ENSG00000221252
 .
 11050
 0.21
chr10_6183056_6183884 0.48 PFKFB3
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
 3411
 0.18
chr13_64046885_64047036 0.48 LINC00395
 long intergenic non-protein coding RNA 395
 244191
 0.02
chr8_17784028_17784466 0.48 PCM1
 pericentriolar material 1
 1994
 0.33
chr13_50940025_50940517 0.48 ENSG00000221198
 .
 2898
 0.4
chr15_57214479_57214630 0.48 TCF12
 transcription factor 12
 3208
 0.26
chr2_12861826_12862019 0.47 TRIB2
 tribbles pseudokinase 2
 3558
 0.31
chr20_62368732_62368892 0.47 LIME1
 Lck interacting transmembrane adaptor 1
 175
 0.82
chr5_125759997_125760148 0.47 GRAMD3
 GRAM domain containing 3
 922
 0.67
chr2_161347323_161347474 0.47 RBMS1
 RNA binding motif, single stranded interacting protein 1
 2631
 0.39
chr9_80454914_80455065 0.47 GNAQ
 guanine nucleotide binding protein (G protein), q polypeptide
 17074
 0.29
chr3_97591431_97591802 0.46 CRYBG3
 beta-gamma crystallin domain containing 3
 4203
 0.29
chr14_99728002_99728348 0.46 AL109767.1
1110
 0.55
chr15_57199778_57200042 0.46 ZNF280D
 zinc finger protein 280D
 10859
 0.22
chr3_69137280_69137433 0.45 ARL6IP5
 ADP-ribosylation-like factor 6 interacting protein 5
 3184
 0.19
chr12_27975145_27975352 0.45 ENSG00000201612
 .
 15925
 0.14
chr1_239711433_239711584 0.45 CHRM3
 cholinergic receptor, muscarinic 3
 80865
 0.11
chr10_121464981_121465132 0.45 INPP5F
 inositol polyphosphate-5-phosphatase F
 20553
 0.2
chr12_50614114_50614771 0.45 RP3-405J10.4
1055
 0.35
chr6_106428787_106428953 0.45 ENSG00000200198
 .
 76622
 0.11
chr17_68133569_68133739 0.45 AC002539.1
8654
 0.19
chr2_205660028_205660179 0.44 PARD3B
 par-3 family cell polarity regulator beta
 249380
 0.02
chr6_106550011_106550199 0.44 RP1-134E15.3
2090
 0.34
chr3_173342884_173343035 0.44 NLGN1
 neuroligin 1
 20570
 0.29
chr10_12762743_12762973 0.44 ENSG00000221331
 .
 4494
 0.33
chrY_18612478_18612629 0.44 ENSG00000252323
 .
 164284
 0.04
chr14_99706254_99706405 0.43 AL109767.1
22956
 0.19
chr10_531510_531790 0.43 RP11-490E15.2
48149
 0.14
chr15_26095881_26096079 0.43 ENSG00000266517
 .
 2008
 0.32
chr1_226919354_226919568 0.43 ITPKB
 inositol-trisphosphate 3-kinase B
 5698
 0.25
chr7_80589868_80590019 0.43 SEMA3C
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
 38268
 0.23
chr11_58341076_58341416 0.42 LPXN
 leupaxin
 2088
 0.26
chr18_60253252_60253584 0.42 ZCCHC2
 zinc finger, CCHC domain containing 2
 46671
 0.15
chr16_50779002_50779153 0.42 RP11-327F22.1
2351
 0.16
chr9_5510404_5511024 0.42 PDCD1LG2
 programmed cell death 1 ligand 2
 144
 0.97
chr11_62308687_62309106 0.42 RP11-864I4.3
4112
 0.1
chr12_47606378_47606570 0.42 PCED1B
 PC-esterase domain containing 1B
 3578
 0.27
chr2_85165728_85166011 0.42 KCMF1
 potassium channel modulatory factor 1
 32347
 0.14
chr13_76867689_76867887 0.42 ENSG00000243274
 .
 158721
 0.04
chr17_8294973_8295124 0.42 RNF222
 ring finger protein 222
 1759
 0.2
chr7_43709455_43709606 0.41 COA1
 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
 19635
 0.2
chr3_12436703_12437398 0.41 PPARG
 peroxisome proliferator-activated receptor gamma
 44079
 0.15
chr1_178096168_178096398 0.41 RASAL2
 RAS protein activator like 2
 33007
 0.24
chr10_3239818_3240224 0.41 PITRM1
 pitrilysin metallopeptidase 1
 25018
 0.22
chr17_18089190_18089923 0.41 RP11-258F1.1
1489
 0.25
chr1_205263608_205263759 0.41 NUAK2
 NUAK family, SNF1-like kinase, 2
 27200
 0.13
chr2_106363775_106364396 0.40 NCK2
 NCK adaptor protein 2
 1897
 0.48
chr17_78735104_78735701 0.39 RP11-28G8.1
44030
 0.16
chr3_128898182_128898356 0.39 CNBP
 CCHC-type zinc finger, nucleic acid binding protein
 4473
 0.15
chr2_102720712_102721707 0.39 IL1R1
 interleukin 1 receptor, type I
 180
 0.96
chrY_16456835_16457019 0.39 ENSG00000266220
 .
 92756
 0.09
chr14_68717009_68717160 0.39 ENSG00000243546
 .
 13828
 0.27
chr20_30948041_30948438 0.39 ASXL1
 additional sex combs like 1 (Drosophila)
 689
 0.71
chr17_75641513_75641796 0.39 SEPT9
 septin 9
 163659
 0.03
chr14_23015461_23015710 0.39 AE000662.92
 Uncharacterized protein
 9949
 0.11
chr14_69130333_69130485 0.39 CTD-2325P2.3
21873
 0.2
chr3_67040557_67040708 0.38 KBTBD8
 kelch repeat and BTB (POZ) domain containing 8
 8095
 0.34
chr3_50354430_50354581 0.38 HYAL2
 hyaluronoglucosaminidase 2
 3874
 0.08
chr6_112145118_112145500 0.38 FYN
 FYN oncogene related to SRC, FGR, YES
 4028
 0.33
chr1_116919885_116920582 0.38 ATP1A1
 ATPase, Na+/K+ transporting, alpha 1 polypeptide
 3744
 0.2
chr3_21788888_21789039 0.38 ZNF385D
 zinc finger protein 385D
 3964
 0.35
chr6_136968777_136969043 0.38 MAP3K5
 mitogen-activated protein kinase kinase kinase 5
 8689
 0.18
chr6_119398292_119398443 0.38 FAM184A
 family with sequence similarity 184, member A
 1170
 0.49
chr1_111215065_111215351 0.38 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 2447
 0.28
chr6_139467434_139467700 0.38 HECA
 headcase homolog (Drosophila)
 11318
 0.25
chr8_102914659_102914810 0.38 ENSG00000238372
 .
 55146
 0.15
chrX_78196699_78196850 0.38 P2RY10
 purinergic receptor P2Y, G-protein coupled, 10
 4055
 0.37
chr1_231762136_231762321 0.37 DISC1
 disrupted in schizophrenia 1
 333
 0.89
chr12_47613140_47613338 0.37 PCED1B
 PC-esterase domain containing 1B
 2858
 0.3
chrX_115456567_115456718 0.37 ENSG00000207033
 .
 75471
 0.11
chr7_28369849_28370167 0.37 CREB5
 cAMP responsive element binding protein 5
 31068
 0.23
chr8_141599639_141599927 0.37 AGO2
 argonaute RISC catalytic component 2
 16204
 0.22
chr12_865415_865972 0.37 WNK1
 WNK lysine deficient protein kinase 1
 2961
 0.28
chr12_92524835_92525431 0.37 C12orf79
 chromosome 12 open reading frame 79
 5664
 0.19
chr20_52199257_52199767 0.37 ZNF217
 zinc finger protein 217
 124
 0.96
chr4_154855782_154855933 0.37 ENSG00000252181
 .
 61254
 0.14
chr1_55701600_55701751 0.37 ENSG00000265822
 .
 10361
 0.22
chr14_22977741_22978031 0.37 TRAJ15
 T cell receptor alpha joining 15
 20694
 0.09
chr5_130617107_130617383 0.36 CDC42SE2
 CDC42 small effector 2
 17452
 0.27
chr5_54450782_54450933 0.36 GPX8
 glutathione peroxidase 8 (putative)
 5089
 0.13
chr13_103357618_103357769 0.36 METTL21C
 methyltransferase like 21C
 10839
 0.14
chr7_150146102_150146542 0.36 GIMAP8
 GTPase, IMAP family member 8
 1396
 0.39
chr1_89531148_89531299 0.36 GBP1
 guanylate binding protein 1, interferon-inducible
 180
 0.94
chrY_15016828_15017148 0.36 DDX3Y
 DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
 246
 0.96
chr5_67576190_67576341 0.36 PIK3R1
 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
 130
 0.98
chr14_22458708_22459003 0.36 ENSG00000238634
 .
 152032
 0.04
chr21_32553132_32553283 0.35 TIAM1
 T-cell lymphoma invasion and metastasis 1
 50668
 0.17
chr9_124991302_124991453 0.35 LHX6
 LIM homeobox 6
 157
 0.94
chr16_80603632_80603783 0.35 RP11-525K10.3
6675
 0.18
chr16_11346250_11346518 0.35 RMI2
 RecQ mediated genome instability 2
 2878
 0.13
chr6_119398487_119399078 0.35 FAM184A
 family with sequence similarity 184, member A
 755
 0.67
chr6_36985827_36986032 0.35 FGD2
 FYVE, RhoGEF and PH domain containing 2
 12506
 0.17
chr6_160883573_160883724 0.35 LPAL2
 lipoprotein, Lp(a)-like 2, pseudogene
 48391
 0.17
chr14_22982199_22982350 0.35 TRAJ15
 T cell receptor alpha joining 15
 16306
 0.1
chr16_86795095_86795257 0.35 FOXL1
 forkhead box L1
 183061
 0.03
chr1_26704591_26705236 0.35 ZNF683
 zinc finger protein 683
 3900
 0.15
chr1_151795357_151795508 0.35 RORC
 RAR-related orphan receptor C
 3135
 0.1
chr10_92079410_92079561 0.34 ENSG00000222451
 .
 155768
 0.04
chr8_128811686_128811837 0.34 ENSG00000249859
 .
 3553
 0.33
chr6_16421411_16421759 0.34 ENSG00000265642
 .
 7169
 0.31
chr2_138710392_138710640 0.34 HNMT
 histamine N-methyltransferase
 11074
 0.32
chr3_5233234_5233385 0.34 EDEM1
 ER degradation enhancer, mannosidase alpha-like 1
 3275
 0.19
chr4_109082592_109082835 0.34 LEF1
 lymphoid enhancer-binding factor 1
 4744
 0.25
chr11_102189311_102189462 0.34 BIRC3
 baculoviral IAP repeat containing 3
 1092
 0.48
chr16_66907243_66907451 0.34 NAE1
 NEDD8 activating enzyme E1 subunit 1
 188
 0.9
chr2_196523306_196523815 0.33 SLC39A10
 solute carrier family 39 (zinc transporter), member 10
 1387
 0.5
chr10_52191698_52191849 0.33 AC069547.2
 Uncharacterized protein
 39007
 0.15
chr17_43389731_43389977 0.33 ENSG00000199953
 .
 15009
 0.13
chr22_40307152_40307436 0.33 GRAP2
 GRB2-related adaptor protein 2
 10181
 0.17
chrX_13680096_13680380 0.33 TCEANC
 transcription elongation factor A (SII) N-terminal and central domain containing
 6824
 0.2
chr8_23075544_23076103 0.33 ENSG00000246582
 .
 6161
 0.12
chr10_134776485_134776636 0.32 TTC40
 tetratricopeptide repeat domain 40
 20233
 0.23
chr10_8099206_8099457 0.32 GATA3
 GATA binding protein 3
 2562
 0.44
chr10_90030880_90031226 0.32 ENSG00000200891
 .
 276601
 0.01
chr6_209971_210123 0.32 DUSP22
 dual specificity phosphatase 22
 81583
 0.11
chr10_124135009_124135427 0.32 PLEKHA1
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
 868
 0.6
chr1_9030857_9031244 0.32 ENSG00000265141
 .
 8883
 0.16
chr1_16292676_16293171 0.32 ZBTB17
 zinc finger and BTB domain containing 17
 9651
 0.13
chr18_67624277_67624428 0.32 CD226
 CD226 molecule
 60
 0.99
chr15_61013207_61013362 0.32 ENSG00000212625
 .
 15684
 0.2
chr9_14029932_14030102 0.32 NFIB
 nuclear factor I/B
 150774
 0.05
chr2_31639599_31639781 0.32 XDH
 xanthine dehydrogenase
 2109
 0.44
chr11_35163942_35164467 0.32 CD44
 CD44 molecule (Indian blood group)
 3351
 0.21
chr8_42748827_42749465 0.32 ENSG00000266044
 .
 2272
 0.19
chr1_78471059_78471251 0.32 DNAJB4
 DnaJ (Hsp40) homolog, subfamily B, member 4
 617
 0.53
chr17_38019811_38019962 0.32 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 493
 0.74
chr17_73680522_73680673 0.31 RP11-474I11.7
282
 0.82
chr3_181342247_181342398 0.31 SOX2-OT
 SOX2 overlapping transcript (non-protein coding)
 13925
 0.28
chr9_128463330_128463481 0.31 MAPKAP1
 mitogen-activated protein kinase associated protein 1
 6051
 0.28
chr21_32533248_32533535 0.31 TIAM1
 T-cell lymphoma invasion and metastasis 1
 30852
 0.23
chr8_135643662_135643813 0.31 ZFAT
 zinc finger and AT hook domain containing
 8386
 0.27
chr15_86247440_86247591 0.31 RP11-815J21.1
3175
 0.16
chr7_2910047_2910285 0.31 GNA12
 guanine nucleotide binding protein (G protein) alpha 12
 26208
 0.2
chr13_98859522_98859872 0.31 ENSG00000263399
 .
 1081
 0.44
chr20_25290950_25291163 0.31 ABHD12
 abhydrolase domain containing 12
 922
 0.6
chr1_85763681_85764097 0.31 ENSG00000264380
 .
 13596
 0.14
chr19_1168749_1168988 0.30 SBNO2
 strawberry notch homolog 2 (Drosophila)
 74
 0.95
chr9_33446136_33446606 0.30 AQP3
 aquaporin 3 (Gill blood group)
 1238
 0.41
chr10_33405368_33405626 0.30 ENSG00000263576
 .
 17933
 0.22
chr2_151335990_151336454 0.30 RND3
 Rho family GTPase 3
 5674
 0.35
chr2_231191950_231192650 0.30 SP140L
 SP140 nuclear body protein-like
 315
 0.92
chr12_33072283_33072434 0.30 PKP2
 plakophilin 2
 22584
 0.26
chr10_47640402_47640757 0.30 ANTXRLP1
 anthrax toxin receptor-like pseudogene 1
 4212
 0.25
chr18_60825953_60826104 0.30 RP11-299P2.1
7475
 0.24
chr2_12862265_12862722 0.30 TRIB2
 tribbles pseudokinase 2
 4129
 0.3
chr15_33493746_33494182 0.30 FMN1
 formin 1
 7067
 0.29
chr6_142948626_142948785 0.30 RP1-67K17.3
120875
 0.06
chr13_110999770_111000142 0.30 COL4A2
 collagen, type IV, alpha 2
 40342
 0.15
chr7_130783126_130783277 0.30 LINC-PINT
 long intergenic non-protein coding RNA, p53 induced transcript
 8588
 0.21
chr9_18268349_18268500 0.30 ADAMTSL1
 ADAMTS-like 1
 205468
 0.03
chr18_64911369_64911711 0.30 ENSG00000265580
 .
 51979
 0.18
chr2_162915924_162916075 0.30 AC008063.2
13767
 0.2
chr6_33384140_33384291 0.30 PHF1
 PHD finger protein 1
 1373
 0.23
chr10_76345165_76345892 0.30 ENSG00000206756
 .
 34378
 0.2
chr7_14022721_14022872 0.29 ETV1
 ets variant 1
 3270
 0.34
chrY_20488207_20488358 0.29 ENSG00000251953
 .
 19842
 0.19
chr1_158902534_158902685 0.29 PYHIN1
 pyrin and HIN domain family, member 1
 1251
 0.51
chrX_2553752_2553903 0.29 CD99P1
 CD99 molecule pseudogene 1
 26371
 0.2
chr2_235402543_235402910 0.29 ARL4C
 ADP-ribosylation factor-like 4C
 2518
 0.45
chr13_41236803_41237000 0.29 FOXO1
 forkhead box O1
 3833
 0.29

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of JUND

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.2 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.5 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.1 0.1 GO:0010661 positive regulation of muscle cell apoptotic process(GO:0010661) positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.1 0.3 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.4 GO:0071731 response to nitric oxide(GO:0071731)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.3 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.3 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) cerebral cortex GABAergic interneuron development(GO:0021894) interneuron migration(GO:1904936)
0.1 0.3 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.2 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.1 0.2 GO:0002913 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.2 GO:0051834 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.3 GO:0072698 protein localization to cytoskeleton(GO:0044380) protein localization to microtubule cytoskeleton(GO:0072698)
0.1 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.2 GO:1901985 positive regulation of histone acetylation(GO:0035066) positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1 0.3 GO:0002507 tolerance induction(GO:0002507)
0.1 0.1 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.1 0.4 GO:0002423 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.1 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.3 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0002713 negative regulation of B cell mediated immunity(GO:0002713) negative regulation of immunoglobulin mediated immune response(GO:0002890)
0.0 0.2 GO:0061117 negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of cardiac muscle tissue development(GO:0055026) negative regulation of cardiac muscle cell proliferation(GO:0060044) negative regulation of heart growth(GO:0061117)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0010957 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.0 GO:0001743 optic placode formation(GO:0001743)
0.0 0.1 GO:0014808 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.0 0.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0007132 meiotic metaphase I(GO:0007132)
0.0 0.3 GO:0048535 lymph node development(GO:0048535)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0045066 regulatory T cell differentiation(GO:0045066)
0.0 0.1 GO:0050932 regulation of melanocyte differentiation(GO:0045634) regulation of pigment cell differentiation(GO:0050932)
0.0 0.1 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135)
0.0 0.3 GO:0031529 ruffle organization(GO:0031529)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.2 GO:0002281 macrophage activation involved in immune response(GO:0002281)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0010716 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0043441 acetoacetic acid biosynthetic process(GO:0043441)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.5 GO:0042130 negative regulation of T cell proliferation(GO:0042130)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.1 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.1 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0032351 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0051323 mitotic metaphase(GO:0000089) metaphase(GO:0051323)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.0 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.0 0.0 GO:0046621 negative regulation of organ growth(GO:0046621)
0.0 0.2 GO:0033687 osteoblast proliferation(GO:0033687)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0015802 basic amino acid transport(GO:0015802)
0.0 0.1 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.0 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.0 0.2 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.0 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.2 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.1 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0032431 activation of phospholipase A2 activity(GO:0032431)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0032691 negative regulation of interleukin-1 beta production(GO:0032691)
0.0 0.0 GO:0051608 histamine transport(GO:0051608)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.0 0.1 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.1 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.0 0.1 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.0 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.1 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.2 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.1 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.0 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0060317 cardiac epithelial to mesenchymal transition(GO:0060317)
0.0 0.4 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.0 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0090312 regulation of protein deacetylation(GO:0090311) positive regulation of protein deacetylation(GO:0090312)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.4 GO:0006997 nucleus organization(GO:0006997)
0.0 0.2 GO:0045885 obsolete positive regulation of survival gene product expression(GO:0045885)
0.0 0.0 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
0.0 0.0 GO:0048289 isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0 0.1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.0 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0032808 lacrimal gland development(GO:0032808)
0.0 0.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.0 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.0 0.1 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.0 GO:0002823 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0060457 negative regulation of digestive system process(GO:0060457)
0.0 0.1 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.0 GO:0060087 relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.0 0.1 GO:0003084 positive regulation of systemic arterial blood pressure(GO:0003084)
0.0 0.0 GO:1903429 regulation of neuron maturation(GO:0014041) regulation of cell maturation(GO:1903429)
0.0 0.0 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.0 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0042308 negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein localization to nucleus(GO:1900181) negative regulation of protein import(GO:1904590)
0.0 0.1 GO:0051642 centrosome localization(GO:0051642)
0.0 0.1 GO:0046541 saliva secretion(GO:0046541)
0.0 0.0 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0016999 antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0 0.1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.0 GO:0090559 regulation of mitochondrial membrane permeability(GO:0046902) regulation of membrane permeability(GO:0090559)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:2000644 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.0 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.0 0.1 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.1 GO:0071326 cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
0.0 0.1 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.0 0.1 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0015840 urea transport(GO:0015840)
0.0 0.0 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.1 GO:0016553 base conversion or substitution editing(GO:0016553)
0.0 0.1 GO:0051597 response to methylmercury(GO:0051597)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.0 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.1 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.0 GO:0060896 neural plate pattern specification(GO:0060896)
0.0 0.0 GO:0055117 regulation of cardiac muscle contraction(GO:0055117)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.1 GO:0010171 body morphogenesis(GO:0010171)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.7 GO:0045178 basal part of cell(GO:0045178)
0.0 0.2 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.0 GO:0031904 endosome lumen(GO:0031904)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0032449 CBM complex(GO:0032449)
0.0 0.1 GO:0031083 BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071778 obsolete WINAC complex(GO:0071778)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0061202 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 0.5 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.0 GO:0030934 anchoring collagen complex(GO:0030934)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0044216 host(GO:0018995) host cell part(GO:0033643) host intracellular part(GO:0033646) intracellular region of host(GO:0043656) host cell(GO:0043657) other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.0 GO:0098642 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 0.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:0000346 transcription export complex(GO:0000346)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.0 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.0 GO:0043260 laminin-11 complex(GO:0043260)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0016151 nickel cation binding(GO:0016151)
0.2 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.4 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 0.2 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.4 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity(GO:0034593)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.0 0.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0043140 ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.1 GO:0042910 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.6 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0034452 dynactin binding(GO:0034452)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.2 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.0 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.0 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0 0.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0031701 angiotensin receptor binding(GO:0031701)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.0 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.1 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.1 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.5 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE