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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for KLF13

Z-value: 0.69

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Transcription factors associated with KLF13

Gene Symbol	Gene ID	Gene Info
KLF13 Ensembl NCBI GeneCards UniProt	ENSG00000169926.5	KLF13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
KLF13	chr15_31732761_31733091	74569	0.120897	-0.91	7.6e-04	Click!
KLF13	chr15_31631556_31631837	440	0.902680	-0.82	6.6e-03	Click!
KLF13	chr15_31637211_31637362	5150	0.331718	-0.81	8.7e-03	Click!
KLF13	chr15_31684023_31684332	25820	0.259140	-0.76	1.9e-02	Click!
KLF13	chr15_31637569_31637720	5508	0.327395	-0.75	2.1e-02	Click!

Activity of the KLF13 motif across conditions

Conditions sorted by the z-value of the KLF13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_49866685_49866836	0.64	DKKL1	dickkopf-like 1	91	0.9
chr17_26554461_26555359	0.56	PYY2	peptide YY, 2 (pseudogene)	578	0.68
chr1_3816010_3816785	0.48	C1orf174	chromosome 1 open reading frame 174	452	0.8
chr12_1613703_1614089	0.44	WNT5B	wingless-type MMTV integration site family, member 5B	25161	0.21
chr17_13505362_13505866	0.43	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	370	0.91
chr19_52452059_52452669	0.42	HCCAT3	hepatocellular carcinoma associated transcript 3 (non-protein coding)	23	0.96
chr19_3606102_3607092	0.42	TBXA2R	thromboxane A2 receptor	61	0.89
chr1_15573540_15574233	0.41	FHAD1	forkhead-associated (FHA) phosphopeptide binding domain 1	110	0.97
chr19_6740138_6741070	0.35	TRIP10	thyroid hormone receptor interactor 10	325	0.81
chr5_133861629_133862874	0.31	JADE2	jade family PHD finger 2	76	0.97
chr17_10102219_10102533	0.30	GAS7	growth arrest-specific 7	508	0.83
chr10_50009233_50009384	0.29	WDFY4	WDFY family member 4	1475	0.49
chr19_51161641_51162497	0.29	C19orf81	chromosome 19 open reading frame 81	9024	0.12
chr6_159239962_159240825	0.28	EZR	ezrin	51	0.96
chr21_32591500_32591929	0.28	TIAM1	T-cell lymphoma invasion and metastasis 1	57369	0.16
chr4_187025490_187026623	0.28	FAM149A	family with sequence similarity 149, member A	175	0.94
chr15_41055526_41056933	0.28	GCHFR	GTP cyclohydrolase I feedback regulator	11	0.96
chr1_25393209_25393360	0.28	ENSG00000264371	.	43290	0.16
chr11_108107293_108107444	0.28	ENSG00000206967	.	7037	0.16
chr5_140797768_140798225	0.27	PCDHGB7	protocadherin gamma subfamily B, 7	569	0.45
chrX_129657730_129658601	0.27	RBMX2	RNA binding motif protein, X-linked 2	122186	0.05
chrX_48910717_48911936	0.26	CCDC120	coiled-coil domain containing 120	225	0.85
chr18_58201323_58201474	0.26	ENSG00000253011	.	20978	0.26
chr17_62705097_62705248	0.26	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	46986	0.12
chr19_49866897_49867069	0.26	DKKL1	dickkopf-like 1	4	0.93
chr9_125830879_125831036	0.25	GPR21	G protein-coupled receptor 21	34151	0.13
chr1_7130330_7130574	0.25	RP11-334N17.1		56113	0.15
chr9_97149391_97149542	0.25	HIATL1	hippocampus abundant transcript-like 1	12633	0.22
chr1_221273332_221273483	0.25	HLX	H2.0-like homeobox	218823	0.02
chr4_4388085_4389202	0.24	NSG1	Homo sapiens neuron specific gene family member 1 (NSG1), transcript variant 3, mRNA.	189	0.96
chr13_33759866_33760149	0.24	STARD13	StAR-related lipid transfer (START) domain containing 13	209	0.95
chr14_93313876_93314027	0.24	GOLGA5	golgin A5	14480	0.25
chr10_94581983_94582410	0.24	EXOC6	exocyst complex component 6	8739	0.28
chr2_121419142_121419293	0.23	ENSG00000201006	.	10368	0.28
chr19_10947512_10947663	0.23	C19orf38	chromosome 19 open reading frame 38	336	0.63
chr11_74442538_74442948	0.23	CHRDL2	chordin-like 2	313	0.84
chr21_34674464_34674615	0.23	IFNAR1	interferon (alpha, beta and omega) receptor 1	22195	0.14
chr5_171604379_171604531	0.23	STK10	serine/threonine kinase 10	10935	0.19
chr1_21934477_21934628	0.22	RAP1GAP	RAP1 GTPase activating protein	11982	0.16
chr1_2210669_2210850	0.21	RP4-713A8.1		47373	0.08
chr10_77168132_77169350	0.21	ENSG00000237149	.	5929	0.2
chr4_141077908_141078102	0.21	MAML3	mastermind-like 3 (Drosophila)	2667	0.32
chr18_25755743_25755974	0.21	CDH2	cadherin 2, type 1, N-cadherin (neuronal)	1552	0.58
chr6_54912113_54912264	0.21	RP3-523K23.2		104223	0.07
chr17_76320400_76320721	0.20	SOCS3	suppressor of cytokine signaling 3	35595	0.11
chr5_129241672_129241829	0.20	CTC-575N7.1		140	0.95
chr1_225670324_225670475	0.20	RP11-496N12.6		17354	0.21
chr16_83987226_83987552	0.20	OSGIN1	oxidative stress induced growth inhibitor 1	545	0.72
chr19_3572978_3573964	0.20	MFSD12	major facilitator superfamily domain containing 12	156	0.77
chr2_740358_740890	0.20	AC092159.3		47389	0.15
chr19_55864944_55865497	0.19	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)	688	0.4
chr14_75744052_75744985	0.19	FOS	FBJ murine osteosarcoma viral oncogene homolog	959	0.51
chr17_60858241_60858392	0.19	MARCH10	membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase	20964	0.21
chr8_105373799_105374058	0.19	DCSTAMP	dendrocyte expressed seven transmembrane protein	13159	0.2
chr15_65023363_65023598	0.18	OAZ2	ornithine decarboxylase antizyme 2	28000	0.09
chr8_9413349_9414633	0.18	RP11-375N15.2		39	0.92
chr1_1118171_1118322	0.18	TTLL10	tubulin tyrosine ligase-like family, member 10	3169	0.1
chr16_11406523_11406823	0.18	ENSG00000199668	.	2251	0.14
chr9_132369899_132370088	0.18	NTMT1	N-terminal Xaa-Pro-Lys N-methyltransferase 1	1170	0.36
chr22_45125363_45125514	0.18	PRR5	proline rich 5 (renal)	1246	0.47
chr19_43968013_43968906	0.18	LYPD3	LY6/PLAUR domain containing 3	1353	0.34
chr2_178937534_178937941	0.18	PDE11A	phosphodiesterase 11A	255	0.92
chr17_41850254_41850405	0.17	DUSP3	dual specificity phosphatase 3	1807	0.22
chr1_159823893_159825316	0.17	C1orf204	chromosome 1 open reading frame 204	533	0.6
chr17_65527492_65527683	0.17	CTD-2653B5.1		6990	0.21
chr20_47406387_47406538	0.17	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	37958	0.18
chr4_16233103_16233254	0.17	TAPT1-AS1	TAPT1 antisense RNA 1 (head to head)	4510	0.23
chr10_67331004_67331235	0.17	ENSG00000253012	.	138699	0.05
chr16_3019207_3020203	0.17	PAQR4	progestin and adipoQ receptor family member IV	146	0.88
chr2_234240529_234240680	0.17	SAG	S-antigen; retina and pineal gland (arrestin)	12410	0.13
chr19_8488969_8489220	0.17	RP11-886P16.6		3617	0.13
chr14_52734332_52734527	0.17	PTGDR	prostaglandin D2 receptor (DP)	2	0.99
chr4_126237829_126238914	0.17	FAT4	FAT atypical cadherin 4	817	0.75
chr19_18451078_18452116	0.17	PGPEP1	pyroglutamyl-peptidase I	148	0.91
chr18_55253153_55254274	0.16	FECH	ferrochelatase	131	0.96
chr5_159742923_159743074	0.16	CCNJL	cyclin J-like	3391	0.22
chr1_186624970_186625121	0.16	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	24514	0.25
chr17_76136415_76136566	0.16	C17orf99	chromosome 17 open reading frame 99	5944	0.12
chr19_862652_862803	0.16	CFD	complement factor D (adipsin)	3037	0.11
chr16_85783565_85784591	0.16	C16orf74	chromosome 16 open reading frame 74	479	0.7
chr11_121315877_121316028	0.16	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	6960	0.25
chr15_68870208_68871184	0.16	CORO2B	coronin, actin binding protein, 2B	612	0.83
chr19_1885517_1885668	0.16	ABHD17A	abhydrolase domain containing 17A	46	0.94
chr2_200327762_200327981	0.16	SATB2	SATB homeobox 2	1960	0.39
chr12_10874089_10875353	0.16	YBX3	Y box binding protein 3	1185	0.46
chr3_126702505_126703684	0.16	PLXNA1	plexin A1	4343	0.34
chr1_245316415_245317636	0.15	KIF26B	kinesin family member 26B	1262	0.47
chr1_153747814_153748820	0.15	SLC27A3	solute carrier family 27 (fatty acid transporter), member 3	549	0.6
chr1_68298302_68298834	0.15	GNG12-AS1	GNG12 antisense RNA 1	576	0.46
chr19_48015922_48016172	0.15	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	12	0.97
chr11_121327677_121327828	0.15	RP11-730K11.1		4030	0.27
chr1_85796394_85796580	0.15	ENSG00000264380	.	46194	0.11
chr6_117591445_117591948	0.15	VGLL2	vestigial like 2 (Drosophila)	4959	0.21
chr2_238315058_238315400	0.15	COL6A3	collagen, type VI, alpha 3	7562	0.22
chr19_9609026_9609526	0.15	ZNF560	zinc finger protein 560	7	0.98
chr3_3338763_3338914	0.15	CRBN	cereblon	117444	0.06
chrX_18372063_18372793	0.15	SCML2	sex comb on midleg-like 2 (Drosophila)	419	0.88
chr17_76164337_76165654	0.15	SYNGR2	synaptogyrin 2	244	0.87
chr19_50354346_50354967	0.14	PTOV1	prostate tumor overexpressed 1	174	0.58
chr6_28109319_28110552	0.14	ZKSCAN8	zinc finger with KRAB and SCAN domains 8	219	0.89
chr20_10530983_10531190	0.14	JAG1	jagged 1	112068	0.06
chr14_75802545_75802696	0.14	FOS	FBJ murine osteosarcoma viral oncogene homolog	55724	0.1
chr11_48002643_48003787	0.14	PTPRJ	protein tyrosine phosphatase, receptor type, J	936	0.61
chr4_87507373_87507524	0.14	MAPK10	mitogen-activated protein kinase 10	7815	0.22
chr10_103589679_103590635	0.14	KCNIP2	Kv channel interacting protein 2	38	0.97
chr15_62684019_62684498	0.13	RP11-299H22.5		121379	0.05
chr16_30933379_30933820	0.13	FBXL19	F-box and leucine-rich repeat protein 19	777	0.32
chr5_95214575_95214839	0.13	ENSG00000250362	.	17217	0.13
chr11_62201492_62201643	0.13	CTD-2531D15.4		7371	0.12
chr22_46067402_46068067	0.13	ATXN10	ataxin 10	55	0.98
chr1_212809700_212810014	0.13	RP11-338C15.5		9744	0.14
chr19_50095334_50096202	0.13	PRR12	proline rich 12	868	0.32
chr5_140625074_140625225	0.13	PCDHB15	protocadherin beta 15	2	0.94
chr7_28771569_28771914	0.13	CREB5	cAMP responsive element binding protein 5	46143	0.2
chr16_88278585_88278779	0.13	ZNF469	zinc finger protein 469	215197	0.02
chr19_1929256_1929607	0.13	CSNK1G2	casein kinase 1, gamma 2	11757	0.09
chr2_208020804_208020955	0.13	KLF7	Kruppel-like factor 7 (ubiquitous)	9416	0.21
chr1_1850096_1850795	0.13	TMEM52	transmembrane protein 52	209	0.9
chr16_29282660_29283032	0.13	RP11-231C14.6		40825	0.13
chr19_52772900_52773931	0.13	ZNF766	zinc finger protein 766	569	0.6
chr19_44905150_44906080	0.12	ZNF285	zinc finger protein 285	126	0.54
chr9_131674102_131674253	0.12	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1	8997	0.11
chr16_67719587_67719738	0.12	C16orf86	chromosome 16 open reading frame 86	18869	0.09
chr17_5069290_5069441	0.12	ZNF594	zinc finger protein 594	18327	0.11
chr11_31892590_31892741	0.12	PAX6	paired box 6	53156	0.13
chr8_22960171_22961001	0.12	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	152	0.94
chr7_86273005_86273208	0.12	GRM3	glutamate receptor, metabotropic 3	124	0.98
chr6_42194447_42194755	0.12	MRPS10	mitochondrial ribosomal protein S10	8998	0.18
chr4_84218783_84218934	0.12	COQ2	coenzyme Q2 4-hydroxybenzoate polyprenyltransferase	12791	0.23
chr5_140787573_140788174	0.12	PCDHGB6	protocadherin gamma subfamily B, 6	103	0.89
chr12_3000030_3000938	0.12	TULP3	tubby like protein 3	411	0.74
chr1_113050561_113051464	0.11	WNT2B	wingless-type MMTV integration site family, member 2B	388	0.86
chr6_11432419_11432570	0.11	NEDD9	neural precursor cell expressed, developmentally down-regulated 9	49913	0.15
chr11_115580481_115580632	0.11	ENSG00000239153	.	82653	0.11
chr16_68280776_68280927	0.11	PLA2G15	phospholipase A2, group XV	1556	0.18
chr3_11651504_11651797	0.11	VGLL4	vestigial like 4 (Drosophila)	328	0.84
chr16_52028189_52028340	0.11	C16orf97	chromosome 16 open reading frame 97	33019	0.23
chr22_38808730_38808891	0.11	RP3-434P1.6		11483	0.12
chr19_14448346_14448497	0.11	CD97	CD97 molecule	43547	0.11
chr19_8656644_8657344	0.11	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	86	0.96
chr1_42230520_42230906	0.11	ENSG00000264896	.	5901	0.3
chr14_35147343_35147800	0.11	ENSG00000253003	.	2474	0.29
chr3_169755608_169756727	0.11	GPR160	G protein-coupled receptor 160	241	0.91
chr21_15588211_15589196	0.11	RBM11	RNA binding motif protein 11	204	0.95
chrX_153619023_153619398	0.11	RPL10	ribosomal protein L10	6285	0.08
chrX_23925220_23926030	0.11	CXorf58	chromosome X open reading frame 58	293	0.62
chr3_51705298_51706076	0.11	TEX264	testis expressed 264	157	0.94
chr12_106621577_106621728	0.11	RP11-651L5.2		19082	0.17
chr9_79520083_79520617	0.11	PRUNE2	prune homolog 2 (Drosophila)	651	0.82
chr14_103394355_103395516	0.10	AMN	amnion associated transmembrane protein	211	0.92
chr21_16388752_16388952	0.10	NRIP1	nuclear receptor interacting protein 1	14163	0.22
chr8_15397591_15398115	0.10	TUSC3	tumor suppressor candidate 3	61	0.98
chr6_3749707_3750198	0.10	RP11-420L9.5		1393	0.41
chr1_20799804_20799955	0.10	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1	12834	0.2
chr6_5084934_5086227	0.10	PPP1R3G	protein phosphatase 1, regulatory subunit 3G	140	0.97
chr17_45500760_45501815	0.10	CTD-2026D20.2		395	0.86
chr19_52130500_52130651	0.10	SIGLEC5	sialic acid binding Ig-like lectin 5	3013	0.15
chr7_93689487_93689638	0.10	BET1	Bet1 golgi vesicular membrane trafficking protein	55868	0.14
chrX_153961154_153961578	0.10	GAB3	GRB2-associated binding protein 3	17966	0.12
chr5_124070851_124071458	0.10	RP11-436H11.5		286	0.82
chr6_167369037_167370142	0.10	RP11-514O12.4		23	0.9
chr6_149775369_149775520	0.10	ZC3H12D	zinc finger CCCH-type containing 12D	2561	0.27
chr10_120788492_120789062	0.10	NANOS1	nanos homolog 1 (Drosophila)	451	0.76
chr19_10341031_10341948	0.10	ENSG00000264266	.	400	0.34
chr19_36360559_36361090	0.10	APLP1	amyloid beta (A4) precursor-like protein 1	262	0.81
chr11_536799_537414	0.10	LRRC56	leucine rich repeat containing 56	421	0.62
chr7_139168164_139168924	0.10	KLRG2	killer cell lectin-like receptor subfamily G, member 2	86	0.97
chr3_55521292_55522040	0.09	WNT5A-AS1	WNT5A antisense RNA 1	61	0.83
chr3_33397369_33397520	0.09	ENSG00000252700	.	58198	0.12
chrX_153569454_153569812	0.09	XX-FW83128A1.2		6246	0.1
chr19_13131054_13131205	0.09	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	3676	0.12
chr16_67197260_67198336	0.09	HSF4	heat shock transcription factor 4	510	0.52
chr2_239140099_239140700	0.09	ENSG00000225057	.	74	0.5
chr19_50141513_50142109	0.09	RRAS	related RAS viral (r-ras) oncogene homolog	1647	0.16
chr9_8857014_8857547	0.09	PTPRD	protein tyrosine phosphatase, receptor type, D	496	0.84
chr18_32618955_32619106	0.09	MAPRE2	microtubule-associated protein, RP/EB family, member 2	2294	0.44
chr8_17940875_17941847	0.09	ASAH1	N-acylsphingosine amidohydrolase (acid ceramidase) 1	242	0.88
chr15_63793174_63793363	0.09	USP3	ubiquitin specific peptidase 3	3525	0.29
chr3_36985452_36986747	0.09	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	449	0.83
chr8_142245284_142245435	0.09	SLC45A4	solute carrier family 45, member 4	4912	0.17
chr11_64759386_64759537	0.09	BATF2	basic leucine zipper transcription factor, ATF-like 2	1715	0.19
chr4_171010363_171010619	0.09	AADAT	aminoadipate aminotransferase	54	0.98
chr8_128924040_128924244	0.09	TMEM75	transmembrane protein 75	36449	0.16
chr4_26263054_26263205	0.09	RBPJ	recombination signal binding protein for immunoglobulin kappa J region	11100	0.31
chr6_41410877_41411028	0.09	ENSG00000238867	.	87765	0.06
chr9_130966078_130966935	0.09	CIZ1	CDKN1A interacting zinc finger protein 1	156	0.85
chr6_158067098_158067249	0.09	ZDHHC14	zinc finger, DHHC-type containing 14	53132	0.16
chr2_231733015_231733166	0.09	ITM2C	integral membrane protein 2C	2711	0.25
chr16_66558097_66558248	0.09	TK2	thymidine kinase 2, mitochondrial	10486	0.1
chr1_226822390_226822541	0.09	ITPKB-IT1	ITPKB intronic transcript 1 (non-protein coding)	24906	0.19
chr15_37391316_37391907	0.09	MEIS2	Meis homeobox 2	14	0.54
chr1_33547337_33547515	0.09	ADC	arginine decarboxylase	425	0.84
chr6_168078748_168078899	0.09	AL009178.1	Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793	117387	0.06
chr17_7608077_7608845	0.09	EFNB3	ephrin-B3	59	0.94
chr1_155011778_155011941	0.09	DCST1	DC-STAMP domain containing 1	5413	0.08
chr20_44650596_44650981	0.09	RP11-465L10.10		76	0.85
chr8_102020336_102020487	0.09	ENSG00000252736	.	45140	0.13
chr12_133137038_133137885	0.09	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	57905	0.1
chr12_95597108_95597270	0.09	FGD6	FYVE, RhoGEF and PH domain containing 6	13966	0.18
chrX_153639895_153640843	0.08	DNASE1L1	deoxyribonuclease I-like 1	51	0.66

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF13

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.3	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.2	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.2	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.1	GO:0071875	adrenergic receptor signaling pathway(GO:0071875) activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0060423	foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.4	GO:0045987	positive regulation of smooth muscle contraction(GO:0045987)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.1	GO:0070189	kynurenine metabolic process(GO:0070189)
0.0	0.0	GO:0003078	obsolete regulation of natriuresis(GO:0003078)
0.0	0.1	GO:0045176	apical protein localization(GO:0045176)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.1	GO:0030238	male sex determination(GO:0030238)
0.0	0.0	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0010193	response to ozone(GO:0010193)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0032048	phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0	0.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.3	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.2	GO:0030818	negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.3	GO:0042133	neurotransmitter metabolic process(GO:0042133)
0.0	0.0	GO:0021508	floor plate formation(GO:0021508)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.0	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0004954	prostanoid receptor activity(GO:0004954)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.1	GO:0016212	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0004321	fatty-acyl-CoA synthase activity(GO:0004321)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.2	GO:0005110	frizzled-2 binding(GO:0005110)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.2	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.3	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.1	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0098988	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.1	GO:0031694	alpha-2A adrenergic receptor binding(GO:0031694)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.1	GO:0004904	interferon receptor activity(GO:0004904)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.0	GO:0004875	complement receptor activity(GO:0004875)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	ST GA13 PATHWAY	G alpha 13 Pathway
0.4	PID RHOA PATHWAY	RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.3	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism