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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for KLF14_SP8

Z-value: 1.39

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Transcription factors associated with KLF14_SP8

Gene Symbol	Gene ID	Gene Info
KLF14 Ensembl NCBI GeneCards UniProt	ENSG00000174595.4	Kruppel like factor 14
SP8 Ensembl NCBI GeneCards UniProt	ENSG00000164651.12	Sp8 transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_130479581_130479757	KLF14	60781	0.118052	-0.62	7.3e-02	Click!
chr7_130419036_130419854	KLF14	557	0.803313	0.58	1.0e-01	Click!
chr7_130479803_130479954	KLF14	60990	0.117627	-0.53	1.5e-01	Click!
chr7_130479062_130479213	KLF14	60249	0.119140	-0.40	2.8e-01	Click!
chr7_130418283_130418896	KLF14	299	0.920213	0.27	4.8e-01	Click!
chr7_20817908_20818122	SP8	8490	0.316917	-0.63	6.8e-02	Click!
chr7_20825584_20825781	SP8	823	0.769500	-0.61	8.4e-02	Click!
chr7_20867011_20867210	SP8	40605	0.218058	-0.58	1.0e-01	Click!
chr7_20818145_20818296	SP8	8285	0.317876	-0.55	1.2e-01	Click!
chr7_20817545_20817735	SP8	8865	0.315258	-0.52	1.5e-01	Click!

Activity of the KLF14_SP8 motif across conditions

Conditions sorted by the z-value of the KLF14_SP8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_72735282_72735631	0.85	RAB37	RAB37, member RAS oncogene family	2085	0.18
chr9_35657964_35658301	0.70	ENSG00000269900	.	118	0.55
chr19_1863868_1864020	0.68	KLF16	Kruppel-like factor 16	377	0.71
chrY_7141670_7141985	0.64	PRKY	protein kinase, Y-linked, pseudogene	509	0.84
chrX_70837784_70838022	0.63	CXCR3	chemokine (C-X-C motif) receptor 3	457	0.81
chr19_47760300_47760580	0.61	CCDC9	coiled-coil domain containing 9	349	0.83
chr2_200775845_200776012	0.61	C2orf69	chromosome 2 open reading frame 69	51	0.97
chr19_19043313_19043520	0.60	HOMER3	homer homolog 3 (Drosophila)	6375	0.1
chr19_52206330_52206564	0.57	ENSG00000208008	.	9940	0.1
chrX_23761387_23761538	0.57	ACOT9	acyl-CoA thioesterase 9	69	0.97
chr4_56719650_56719801	0.57	EXOC1	exocyst complex component 1	57	0.98
chr20_35064561_35064931	0.56	DLGAP4	discs, large (Drosophila) homolog-associated protein 4	4625	0.27
chr1_33429362_33429936	0.53	RNF19B	ring finger protein 19B	637	0.63
chr8_42751519_42751741	0.52	RNF170	ring finger protein 170	98	0.6
chr10_134357786_134358024	0.52	INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	6262	0.23
chr13_52158020_52158278	0.52	WDFY2	WD repeat and FYVE domain containing 2	495	0.7
chr20_62708665_62709256	0.50	RGS19	regulator of G-protein signaling 19	1885	0.17
chr9_137820763_137820914	0.49	FCN1	ficolin (collagen/fibrinogen domain containing) 1	11029	0.14
chr8_82598573_82598858	0.48	IMPA1	inositol(myo)-1(or 4)-monophosphatase 1	149	0.95
chr19_56116555_56116820	0.48	ZNF865	zinc finger protein 865	84	0.91
chr22_40058332_40058676	0.47	CACNA1I	calcium channel, voltage-dependent, T type, alpha 1I subunit	91746	0.07
chr2_106362063_106362974	0.47	NCK2	NCK adaptor protein 2	330	0.94
chr3_48693750_48694330	0.47	CELSR3	cadherin, EGF LAG seven-pass G-type receptor 3	6308	0.1
chr7_6543400_6543638	0.46	KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	19646	0.12
chr2_105654416_105654567	0.46	MRPS9	mitochondrial ribosomal protein S9	50	0.88
chr19_1471181_1471332	0.46	C19orf25	chromosome 19 open reading frame 25	7640	0.07
chr6_26157067_26157487	0.46	HIST1H1E	histone cluster 1, H1e	718	0.34
chr19_41381332_41381529	0.45	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	7227	0.14
chr6_139644906_139645379	0.45	TXLNB	taxilin beta	31866	0.17
chrX_134555719_134555870	0.45	ENSG00000201440	.	6416	0.24
chr19_50370762_50370913	0.45	PNKP	polynucleotide kinase 3'-phosphatase	4	0.92
chr1_209979523_209979948	0.45	IRF6	interferon regulatory factor 6	270	0.89
chr13_98085447_98085685	0.43	RAP2A	RAP2A, member of RAS oncogene family	910	0.7
chr2_739909_740321	0.43	AC092159.3		46880	0.15
chr22_46409603_46410227	0.43	WNT7B	wingless-type MMTV integration site family, member 7B	36906	0.09
chr4_70624988_70625315	0.42	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	1165	0.59
chr19_39971076_39971318	0.42	TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	145	0.91
chr12_53448318_53448482	0.41	RP11-983P16.4		178	0.91
chr12_121124364_121124573	0.41	MLEC	malectin	204	0.89
chr19_19932661_19932812	0.41	ZNF506	zinc finger protein 506	176	0.93
chr19_11546030_11546251	0.40	PRKCSH	protein kinase C substrate 80K-H	31	0.69
chr19_43967756_43967988	0.40	LYPD3	LY6/PLAUR domain containing 3	1940	0.25
chr17_79480580_79480790	0.40	RP13-766D20.2		388	0.6
chr19_4069446_4069597	0.40	ZBTB7A	zinc finger and BTB domain containing 7A	2578	0.17
chrX_15756367_15757484	0.40	CA5B	carbonic anhydrase VB, mitochondrial	532	0.77
chr1_228247617_228247954	0.39	ARF1	ADP-ribosylation factor 1	22576	0.12
chr19_33668057_33668280	0.39	ENSG00000264355	.	190	0.63
chr6_33285612_33285875	0.39	ZBTB22	zinc finger and BTB domain containing 22	24	0.94
chr5_141228722_141229210	0.38	PCDH1	protocadherin 1	20188	0.18
chr7_76009058_76009398	0.38	ZP3	zona pellucida glycoprotein 3 (sperm receptor)	17607	0.14
chr19_54974999_54975150	0.38	LENG9	leukocyte receptor cluster (LRC) member 9	180	0.88
chr19_50354007_50354329	0.38	PTOV1	prostate tumor overexpressed 1	30	0.62
chr8_27631821_27631972	0.38	ESCO2	establishment of sister chromatid cohesion N-acetyltransferase 2	7	0.92
chr17_2305075_2305389	0.38	MNT	MAX network transcriptional repressor	820	0.48
chr11_73499157_73499522	0.37	MRPL48	mitochondrial ribosomal protein L48	364	0.84
chr7_75622802_75623087	0.36	POR	P450 (cytochrome) oxidoreductase	11715	0.16
chr2_85153190_85153512	0.36	TMSB10	thymosin beta 10	20602	0.17
chr19_14277944_14278210	0.36	LPHN1	latrophilin 1	5729	0.13
chr22_24836933_24837084	0.35	ADORA2A	adenosine A2a receptor	8200	0.18
chr2_99346083_99347252	0.35	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A	44	0.98
chr12_111843317_111843547	0.35	SH2B3	SH2B adaptor protein 3	320	0.89
chr16_23568698_23568990	0.35	EARS2	glutamyl-tRNA synthetase 2, mitochondrial	148	0.5
chr19_18507804_18508682	0.35	LRRC25	leucine rich repeat containing 25	178	0.89
chr19_1259509_1259817	0.35	CIRBP	cold inducible RNA binding protein	279	0.79
chr9_34637885_34638036	0.35	SIGMAR1	sigma non-opioid intracellular receptor 1	154	0.89
chr16_87887371_87887580	0.35	SLC7A5	solute carrier family 7 (amino acid transporter light chain, L system), member 5	9770	0.17
chr10_29971115_29971266	0.35	ENSG00000222092	.	29654	0.19
chr19_46296191_46296342	0.34	DMWD	dystrophia myotonica, WD repeat containing	206	0.85
chr8_145027093_145027557	0.34	PLEC	plectin	763	0.48
chr2_10184175_10184326	0.34	KLF11	Kruppel-like factor 11	52	0.96
chr12_122231286_122231671	0.34	RHOF	ras homolog family member F (in filopodia)	212	0.92
chr21_37693064_37693535	0.34	AP000692.10		331	0.74
chr7_129420780_129420931	0.33	ENSG00000207691	.	6001	0.16
chr7_100608890_100609145	0.33	ENSG00000225946	.	1170	0.36
chr6_15017657_15017961	0.33	ENSG00000242989	.	95390	0.09
chr8_144328822_144328973	0.33	ZFP41	ZFP41 zinc finger protein	94	0.95
chr6_167369037_167370142	0.33	RP11-514O12.4		23	0.9
chr1_95582420_95583278	0.33	TMEM56	transmembrane protein 56	45	0.91
chrX_49087091_49087667	0.33	CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit	2392	0.13
chr1_161008159_161008677	0.33	TSTD1	thiosulfate sulfurtransferase (rhodanese)-like domain containing 1	101	0.93
chr4_109571201_109571501	0.33	OSTC	oligosaccharyltransferase complex subunit (non-catalytic)	389	0.83
chr11_44586532_44586926	0.33	CD82	CD82 molecule	412	0.88
chr1_154297288_154297551	0.33	ATP8B2	ATPase, aminophospholipid transporter, class I, type 8B, member 2	610	0.54
chrX_15756078_15756346	0.33	CA5B	carbonic anhydrase VB, mitochondrial	181	0.94
chr16_50186155_50186662	0.33	PAPD5	PAP associated domain containing 5	421	0.65
chr1_12240704_12240855	0.33	ENSG00000263676	.	10991	0.15
chr19_6767732_6768139	0.32	SH2D3A	SH2 domain containing 3A	336	0.81
chr14_24563143_24563294	0.32	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	44	0.92
chr6_13486899_13487420	0.32	GFOD1	glucose-fructose oxidoreductase domain containing 1	628	0.33
chr19_46171409_46171560	0.32	GIPR	gastric inhibitory polypeptide receptor	18	0.94
chrX_153237672_153237823	0.32	TMEM187	transmembrane protein 187	31	0.87
chr17_26367818_26368453	0.32	NLK	nemo-like kinase	1047	0.46
chr1_158768566_158768717	0.32	OR6N2	olfactory receptor, family 6, subfamily N, member 2	21216	0.14
chr16_66907243_66907451	0.32	NAE1	NEDD8 activating enzyme E1 subunit 1	188	0.9
chr16_30933379_30933820	0.31	FBXL19	F-box and leucine-rich repeat protein 19	777	0.32
chr7_100449970_100450197	0.31	RP11-126L15.4		155	0.62
chr20_61609029_61609180	0.31	SLC17A9	solute carrier family 17 (vesicular nucleotide transporter), member 9	24706	0.13
chr22_44577166_44577317	0.31	PARVG	parvin, gamma	16	0.99
chr1_43736638_43736898	0.31	TMEM125	transmembrane protein 125	151	0.94
chr17_6927262_6927413	0.30	BCL6B	B-cell CLL/lymphoma 6, member B	541	0.5
chr18_60822617_60822842	0.30	RP11-299P2.1		4176	0.28
chr11_65314232_65314500	0.30	LTBP3	latent transforming growth factor beta binding protein 3	136	0.91
chr19_19843994_19844145	0.30	ZNF14	zinc finger protein 14	163	0.94
chr11_67250873_67251362	0.30	AIP	aryl hydrocarbon receptor interacting protein	605	0.49
chr1_23671004_23671532	0.30	HNRNPR	heterogeneous nuclear ribonucleoprotein R	439	0.78
chr2_113931904_113932161	0.30	PSD4	pleckstrin and Sec7 domain containing 4	458	0.63
chr15_45353241_45353392	0.30	RP11-109D20.1		2411	0.16
chr6_37017654_37018643	0.30	COX6A1P2	cytochrome c oxidase subunit VIa polypeptide 1 pseudogene 2	5541	0.22
chr1_25291828_25291979	0.30	RUNX3	runt-related transcription factor 3	402	0.86
chr14_23066902_23067968	0.30	ABHD4	abhydrolase domain containing 4	228	0.67
chr20_48806660_48807137	0.30	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	478	0.82
chr8_145026531_145026952	0.29	PLEC	plectin	1347	0.28
chr2_179914401_179914980	0.29	CCDC141	coiled-coil domain containing 141	96	0.98
chr1_228247282_228247590	0.29	ARF1	ADP-ribosylation factor 1	22925	0.12
chr1_21934477_21934628	0.29	RAP1GAP	RAP1 GTPase activating protein	11982	0.16
chr6_31588350_31588565	0.29	PRRC2A	proline-rich coiled-coil 2A	40	0.9
chr19_49403542_49403703	0.29	NUCB1	nucleobindin 1	5	0.94
chr14_105218972_105219273	0.29	SIVA1	SIVA1, apoptosis-inducing factor	315	0.83
chr5_142149418_142149898	0.29	ARHGAP26	Rho GTPase activating protein 26	291	0.94
chr8_19614026_19614514	0.28	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1	546	0.85
chr19_36394196_36394709	0.28	HCST	hematopoietic cell signal transducer	1012	0.27
chr11_441689_441900	0.28	ANO9	anoctamin 9	217	0.82
chr1_92949289_92949440	0.28	GFI1	growth factor independent 1 transcription repressor	147	0.97
chr9_131549144_131549417	0.27	TBC1D13	TBC1 domain family, member 13	203	0.89
chr4_89444930_89445081	0.27	PYURF	PIGY upstream reading frame	41	0.49
chr6_33378848_33379665	0.27	PHF1	PHD finger protein 1	518	0.64
chr17_80186000_80186228	0.27	SLC16A3	solute carrier family 16 (monocarboxylate transporter), member 3	159	0.91
chr1_33565203_33565487	0.27	ADC	arginine decarboxylase	17494	0.18
chr16_23521764_23521915	0.27	GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	24	0.97
chr6_44238340_44238491	0.27	TMEM151B	transmembrane protein 151B	65	0.95
chr11_108107293_108107444	0.27	ENSG00000206967	.	7037	0.16
chrX_102942081_102942371	0.27	MORF4L2-AS1	MORF4L2 antisense RNA 1	14	0.89
chr4_39640581_39640786	0.27	SMIM14	small integral membrane protein 14	27	0.98
chr19_19314271_19314456	0.26	NR2C2AP	nuclear receptor 2C2-associated protein	130	0.92
chr1_45452336_45452487	0.26	EIF2B3	eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa	129	0.95
chr17_7232727_7233032	0.26	NEURL4	neuralized E3 ubiquitin protein ligase 4	167	0.85
chr7_100609378_100609553	0.26	ENSG00000225946	.	1618	0.27
chr19_46145541_46145808	0.26	EML2	echinoderm microtubule associated protein like 2	146	0.84
chr1_182808109_182808399	0.26	DHX9	DEAH (Asp-Glu-Ala-His) box helicase 9	250	0.93
chr19_8373328_8373540	0.26	CD320	CD320 molecule	195	0.9
chr7_6065805_6065956	0.26	EIF2AK1	eukaryotic translation initiation factor 2-alpha kinase 1	303	0.79
chr1_92950112_92951112	0.26	GFI1	growth factor independent 1 transcription repressor	1016	0.65
chr19_38908265_38908571	0.26	RASGRP4	RAS guanyl releasing protein 4	8384	0.09
chr1_17027244_17027474	0.26	ESPNP	espin pseudogene	9755	0.12
chr8_1873560_1873711	0.26	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	42813	0.16
chr1_43814755_43814906	0.26	RP1-92O14.3		9499	0.1
chr3_41159090_41159342	0.26	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	77112	0.12
chr1_27687106_27687257	0.26	MAP3K6	mitogen-activated protein kinase kinase kinase 6	3261	0.15
chr19_41076676_41076827	0.26	SHKBP1	SH3KBP1 binding protein 1	6006	0.15
chr3_128399436_128399670	0.25	RPN1	ribophorin I	365	0.87
chr18_9136832_9137023	0.25	ANKRD12	ankyrin repeat domain 12	133	0.7
chr19_10405987_10406645	0.25	ICAM5	intercellular adhesion molecule 5, telencephalin	4663	0.08
chr4_185905126_185905277	0.25	HELT	helt bHLH transcription factor	34794	0.17
chr2_242823909_242824060	0.25	AC131097.3		115	0.94
chr1_113932474_113932894	0.25	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	687	0.82
chr19_11708084_11708235	0.25	ZNF627	zinc finger protein 627	76	0.95
chr19_1248254_1248405	0.25	MIDN	midnolin	223	0.84
chr22_21904288_21904712	0.25	RIMBP3C	RIMS binding protein 3C	620	0.4
chr3_15643230_15643437	0.25	HACL1	2-hydroxyacyl-CoA lyase 1	5	0.5
chr9_99775769_99776027	0.25	HIATL2	hippocampus abundant transcript-like 2	36	0.98
chr19_18169019_18169282	0.25	IL12RB1	interleukin 12 receptor, beta 1	28592	0.11
chr17_8869162_8869418	0.25	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	266	0.94
chr22_38143411_38143562	0.25	TRIOBP	TRIO and F-actin binding protein	1209	0.34
chr17_76128459_76128696	0.25	TMC6	transmembrane channel-like 6	89	0.94
chr22_36805845_36806656	0.25	MYH9	myosin, heavy chain 9, non-muscle	22187	0.14
chr6_39197260_39197532	0.25	KCNK5	potassium channel, subfamily K, member 5	170	0.97
chr21_37757459_37757644	0.25	CHAF1B	chromatin assembly factor 1, subunit B (p60)	125	0.95
chr6_15244761_15245107	0.24	JARID2	jumonji, AT rich interactive domain 2	1593	0.39
chr9_91149598_91149758	0.24	NXNL2	nucleoredoxin-like 2	338	0.93
chr7_63360438_63360674	0.24	ENSG00000263891	.	890	0.66
chr6_106960080_106960316	0.24	AIM1	absent in melanoma 1	468	0.83
chr16_28936114_28936278	0.24	RABEP2	rabaptin, RAB GTPase binding effector protein 2	48	0.94
chr1_244997779_244998465	0.24	COX20	COX20 cytochrome C oxidase assembly factor	502	0.79
chr7_98971773_98972192	0.24	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	100	0.95
chr3_49711420_49711660	0.24	APEH	acylaminoacyl-peptide hydrolase	93	0.95
chr7_419674_419948	0.24	AC187652.1	Protein LOC100996433	116893	0.06
chr19_45250325_45250702	0.24	BCL3	B-cell CLL/lymphoma 3	1291	0.3
chr6_99281611_99282230	0.24	POU3F2	POU class 3 homeobox 2	660	0.83
chr1_150898338_150898685	0.24	SETDB1	SET domain, bifurcated 1	228	0.88
chr3_128322813_128322964	0.24	C3orf27	chromosome 3 open reading frame 27	27959	0.17
chr17_19015403_19015696	0.24	ENSG00000262202	.	400	0.71
chr17_56412690_56412841	0.24	ENSG00000264399	.	618	0.54
chr1_158770848_158771118	0.24	OR6N2	olfactory receptor, family 6, subfamily N, member 2	23558	0.13
chr17_60005390_60005541	0.24	INTS2	integrator complex subunit 2	88	0.97
chr14_105527834_105528220	0.24	GPR132	G protein-coupled receptor 132	3740	0.23
chr21_43187252_43187510	0.24	RIPK4	receptor-interacting serine-threonine kinase 4	115	0.97
chr11_48002643_48003787	0.24	PTPRJ	protein tyrosine phosphatase, receptor type, J	936	0.61
chr5_137687830_137688196	0.24	KDM3B	lysine (K)-specific demethylase 3B	272	0.86
chr19_908590_909250	0.24	R3HDM4	R3H domain containing 4	4311	0.09
chr9_130980718_130981301	0.24	CIZ1	CDKN1A interacting zinc finger protein 1	14347	0.08
chr7_149470838_149471041	0.24	ZNF467	zinc finger protein 467	371	0.88
chr1_15322600_15322751	0.24	KAZN	kazrin, periplakin interacting protein	50260	0.17
chr5_133801504_133801725	0.24	ENSG00000207222	.	34361	0.12
chr9_139438785_139439162	0.24	NOTCH1	notch 1	1341	0.19
chr16_10837712_10837925	0.23	NUBP1	nucleotide binding protein 1	106	0.97
chr20_54933667_54933884	0.23	FAM210B	family with sequence similarity 210, member B	196	0.94
chr19_36134154_36134758	0.23	ETV2	ets variant 2	112	0.91
chr16_84178353_84178718	0.23	HSDL1	hydroxysteroid dehydrogenase like 1	226	0.6
chr11_67381317_67381845	0.23	NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	5884	0.1
chr17_43306742_43306893	0.23	CTD-2020K17.1		7228	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0010957	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.1	0.4	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.1	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.4	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.1	0.9	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.5	GO:0032486	Rap protein signal transduction(GO:0032486)
0.1	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.3	GO:0034421	post-translational protein acetylation(GO:0034421)
0.1	0.4	GO:0034063	stress granule assembly(GO:0034063)
0.1	0.5	GO:0046855	phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.1	0.2	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.1	0.6	GO:0007172	signal complex assembly(GO:0007172)
0.1	0.2	GO:0052306	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308)
0.1	0.2	GO:0034723	DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.1	0.4	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.1	0.4	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	0.2	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.1	0.3	GO:0006924	activation-induced cell death of T cells(GO:0006924)
0.1	0.4	GO:0016584	nucleosome positioning(GO:0016584)
0.1	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	0.3	GO:0008216	spermidine metabolic process(GO:0008216)
0.1	0.5	GO:0043558	regulation of translational initiation in response to stress(GO:0043558)
0.1	0.2	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	0.2	GO:1901534	positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.1	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.2	GO:0009997	negative regulation of heart induction by canonical Wnt signaling pathway(GO:0003136) negative regulation of cardioblast cell fate specification(GO:0009997) cardioblast cell fate commitment(GO:0042684) cardioblast cell fate specification(GO:0042685) regulation of cardioblast cell fate specification(GO:0042686) negative regulation of cardioblast differentiation(GO:0051892) cardiac cell fate specification(GO:0060912) negative regulation of heart induction(GO:1901320) negative regulation of cardiocyte differentiation(GO:1905208) regulation of cardiac cell fate specification(GO:2000043) negative regulation of cardiac cell fate specification(GO:2000044)
0.1	0.3	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.1	0.2	GO:0032790	ribosome disassembly(GO:0032790)
0.1	0.2	GO:1901532	regulation of megakaryocyte differentiation(GO:0045652) regulation of hematopoietic progenitor cell differentiation(GO:1901532)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.1	0.2	GO:0043441	acetoacetic acid biosynthetic process(GO:0043441)
0.1	0.1	GO:0021860	pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0046174	polyol catabolic process(GO:0046174)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.1	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.0	0.1	GO:2000192	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0019605	butyrate metabolic process(GO:0019605)
0.0	0.0	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0034088	maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.0	0.2	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.4	GO:0006107	oxaloacetate metabolic process(GO:0006107)
0.0	0.2	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.1	GO:0031558	obsolete induction of apoptosis in response to chemical stimulus(GO:0031558)
0.0	0.2	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.2	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.0	0.1	GO:2000757	negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0	0.4	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:2000319	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0	0.0	GO:0002363	alpha-beta T cell lineage commitment(GO:0002363)
0.0	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.2	GO:0050665	hydrogen peroxide biosynthetic process(GO:0050665)
0.0	0.2	GO:0042416	dopamine biosynthetic process(GO:0042416)
0.0	0.2	GO:0051016	barbed-end actin filament capping(GO:0051016)
0.0	0.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0002666	lymphocyte anergy(GO:0002249) T cell tolerance induction(GO:0002517) regulation of T cell tolerance induction(GO:0002664) positive regulation of T cell tolerance induction(GO:0002666) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.5	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.4	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.0	0.2	GO:0050849	negative regulation of calcium-mediated signaling(GO:0050849)
0.0	0.1	GO:0048289	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.1	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0	0.2	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.0	0.4	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0097501	detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.5	GO:0035967	cellular response to topologically incorrect protein(GO:0035967)
0.0	0.1	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.1	GO:0032656	regulation of interleukin-13 production(GO:0032656)
0.0	0.1	GO:0002885	positive regulation of hypersensitivity(GO:0002885)
0.0	0.4	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.3	GO:0035964	COPI-coated vesicle budding(GO:0035964) Golgi vesicle budding(GO:0048194) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.2	GO:0033261	obsolete regulation of S phase(GO:0033261)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.4	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0048368	lateral mesoderm development(GO:0048368)
0.0	0.0	GO:0051788	response to misfolded protein(GO:0051788)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0021684	cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0010447	response to acidic pH(GO:0010447)
0.0	0.1	GO:0042483	negative regulation of odontogenesis(GO:0042483)
0.0	0.2	GO:0042403	thyroid hormone metabolic process(GO:0042403)
0.0	0.0	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.2	GO:0046037	GMP metabolic process(GO:0046037)
0.0	0.1	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.0	GO:0033591	response to L-ascorbic acid(GO:0033591)
0.0	0.1	GO:0001821	histamine secretion(GO:0001821)
0.0	0.5	GO:0001836	release of cytochrome c from mitochondria(GO:0001836)
0.0	0.1	GO:0021801	cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.1	GO:0016999	antibiotic metabolic process(GO:0016999) antibiotic biosynthetic process(GO:0017000)
0.0	0.1	GO:0015801	aromatic amino acid transport(GO:0015801)
0.0	0.1	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.1	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0042520	tyrosine phosphorylation of Stat4 protein(GO:0042504) regulation of tyrosine phosphorylation of Stat4 protein(GO:0042519) positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.2	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.1	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.2	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0045910	negative regulation of DNA recombination(GO:0045910)
0.0	0.1	GO:0009698	phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804)
0.0	0.0	GO:0033087	negative regulation of T cell differentiation in thymus(GO:0033085) negative regulation of immature T cell proliferation(GO:0033087) negative regulation of immature T cell proliferation in thymus(GO:0033088) negative regulation of thymocyte aggregation(GO:2000399)
0.0	0.3	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0042178	xenobiotic catabolic process(GO:0042178)
0.0	0.6	GO:0043487	regulation of RNA stability(GO:0043487)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.0	GO:0019255	glucose 1-phosphate metabolic process(GO:0019255)
0.0	0.2	GO:0046718	viral entry into host cell(GO:0046718)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.3	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0034405	response to fluid shear stress(GO:0034405)
0.0	0.1	GO:1901970	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.1	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.0	0.1	GO:0001916	regulation of T cell mediated cytotoxicity(GO:0001914) positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0	0.0	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.3	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:1902745	positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0	0.1	GO:0042921	corticosteroid receptor signaling pathway(GO:0031958) glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:1904063	negative regulation of calcium ion import(GO:0090281) negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.2	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0034616	response to laminar fluid shear stress(GO:0034616)
0.0	0.0	GO:0060433	bronchus development(GO:0060433)
0.0	0.1	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0002829	negative regulation of type 2 immune response(GO:0002829)
0.0	0.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.1	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0034331	cell junction maintenance(GO:0034331) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0	0.3	GO:0045576	mast cell activation(GO:0045576)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.1	GO:0034447	very-low-density lipoprotein particle clearance(GO:0034447)
0.0	0.3	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.2	GO:0090004	positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0	0.1	GO:0016137	glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	0.0	GO:0031342	negative regulation of cell killing(GO:0031342)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:0009180	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0031272	pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.3	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0033197	response to vitamin E(GO:0033197)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0045343	MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.0	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0	0.0	GO:0046006	regulation of activated T cell proliferation(GO:0046006)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.0	GO:0060179	male mating behavior(GO:0060179)
0.0	0.0	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.0	GO:1903224	endodermal cell fate commitment(GO:0001711) endodermal cell fate specification(GO:0001714) endodermal cell differentiation(GO:0035987) regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0	0.0	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.0	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.0	GO:0044320	cellular response to leptin stimulus(GO:0044320) response to leptin(GO:0044321)
0.0	0.1	GO:0045040	outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0034625	fatty acid elongation, monounsaturated fatty acid(GO:0034625)
0.0	0.0	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0018027	peptidyl-lysine dimethylation(GO:0018027)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0051322	anaphase(GO:0051322)
0.0	0.0	GO:0009134	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.0	0.1	GO:0015904	tetracycline transport(GO:0015904) antibiotic transport(GO:0042891) toxin transport(GO:1901998)
0.0	0.1	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.0	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0016199	axon midline choice point recognition(GO:0016199)
0.0	0.0	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.0	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.2	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.0	0.0	GO:0072193	positive regulation of smooth muscle cell differentiation(GO:0051152) ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0010624	regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.0	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.0	GO:0015809	arginine transport(GO:0015809)
0.0	0.7	GO:0006406	mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0	0.0	GO:2000189	regulation of cholesterol homeostasis(GO:2000188) positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0	0.1	GO:0006044	N-acetylglucosamine metabolic process(GO:0006044)
0.0	0.1	GO:0002063	chondrocyte development(GO:0002063)
0.0	0.2	GO:0018904	glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0	0.1	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.0	0.0	GO:0009301	snRNA transcription(GO:0009301)
0.0	0.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.1	GO:0042119	granulocyte activation(GO:0036230) neutrophil activation(GO:0042119)
0.0	0.0	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	0.1	GO:0030889	negative regulation of B cell proliferation(GO:0030889)
0.0	0.0	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0045978	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0015840	urea transport(GO:0015840)
0.0	0.0	GO:0001881	receptor recycling(GO:0001881)
0.0	0.6	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.1	GO:0032770	positive regulation of monooxygenase activity(GO:0032770)
0.0	0.0	GO:0051873	disruption by host of symbiont cells(GO:0051852) killing by host of symbiont cells(GO:0051873)
0.0	0.1	GO:0045003	DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.0	0.0	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.0	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.0	GO:0051132	NK T cell activation(GO:0051132)
0.0	0.0	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.3	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.2	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.2	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.1	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.0	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.1	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.1	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0015853	adenine transport(GO:0015853)
0.0	0.2	GO:0046131	pyrimidine ribonucleoside metabolic process(GO:0046131)
0.0	0.0	GO:0032808	lacrimal gland development(GO:0032808)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.2	GO:0000080	mitotic G1 phase(GO:0000080)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.0	0.0	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.1	GO:0072659	protein localization to plasma membrane(GO:0072659) protein localization to cell periphery(GO:1990778)
0.0	0.0	GO:0003077	obsolete negative regulation of diuresis(GO:0003077)
0.0	0.1	GO:0016577	histone demethylation(GO:0016577)
0.0	0.1	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.1	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0	0.1	GO:0008608	attachment of spindle microtubules to kinetochore(GO:0008608)
0.0	0.0	GO:0032922	circadian regulation of gene expression(GO:0032922)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)
0.0	0.0	GO:0045990	carbon catabolite regulation of transcription(GO:0045990) regulation of transcription by glucose(GO:0046015)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0000145	exocyst(GO:0000145)
0.1	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0008537	proteasome activator complex(GO:0008537)
0.1	0.3	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.5	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.3	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.0	0.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.4	GO:0031080	nuclear pore outer ring(GO:0031080)
0.0	0.3	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.3	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.4	GO:0032039	integrator complex(GO:0032039)
0.0	0.4	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.4	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0031205	endoplasmic reticulum Sec complex(GO:0031205)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.5	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	0.2	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.4	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.0	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.3	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0030893	meiotic cohesin complex(GO:0030893)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.5	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.2	GO:0032156	septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0	0.3	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.1	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:1903561	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.3	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0031083	BLOC complex(GO:0031082) BLOC-1 complex(GO:0031083)
0.0	0.0	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.0	GO:0072487	MSL complex(GO:0072487)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.0	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0060203	clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.2	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.3	GO:0016234	inclusion body(GO:0016234)
0.0	0.1	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.8	GO:0000786	nucleosome(GO:0000786)
0.0	0.1	GO:0043073	germ cell nucleus(GO:0043073)
0.0	0.0	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.0	GO:0000805	X chromosome(GO:0000805)
0.0	0.0	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.0	GO:0044462	external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0005838	proteasome regulatory particle(GO:0005838) proteasome accessory complex(GO:0022624)
0.0	0.2	GO:0034385	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.6	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.1	0.3	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1	0.3	GO:0000247	C-8 sterol isomerase activity(GO:0000247)
0.1	0.5	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.1	0.3	GO:0047238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1	0.3	GO:0046923	ER retention sequence binding(GO:0046923)
0.1	0.3	GO:0015355	secondary active monocarboxylate transmembrane transporter activity(GO:0015355)
0.1	0.2	GO:0042608	T cell receptor binding(GO:0042608)
0.1	0.3	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.1	0.4	GO:0031491	nucleosome binding(GO:0031491)
0.1	0.2	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.5	GO:0030371	translation repressor activity(GO:0030371)
0.1	0.2	GO:0046980	tapasin binding(GO:0046980)
0.1	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1	0.2	GO:0003896	DNA primase activity(GO:0003896)
0.1	0.2	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.1	0.3	GO:0004075	biotin carboxylase activity(GO:0004075)
0.1	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(GO:0052659)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.9	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0032450	maltose alpha-glucosidase activity(GO:0032450)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.3	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.2	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.3	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0070735	protein-glycine ligase activity(GO:0070735)
0.0	0.4	GO:0008198	ferrous iron binding(GO:0008198)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.4	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.2	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.2	GO:0070087	chromo shadow domain binding(GO:0070087)
0.0	0.4	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.0	GO:0046977	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.3	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0070492	oligosaccharide binding(GO:0070492)
0.0	0.4	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0004803	transposase activity(GO:0004803)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0016417	S-acyltransferase activity(GO:0016417)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.3	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.0	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.1	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.5	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340)
0.0	0.3	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.9	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.4	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.1	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0015520	tetracycline:proton antiporter activity(GO:0015520)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0061630	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.4	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.0	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.0	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.0	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.2	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0042605	peptide antigen binding(GO:0042605)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.2	GO:0003709	obsolete RNA polymerase III transcription factor activity(GO:0003709)
0.0	0.2	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.0	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.0	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.3	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0016986	obsolete transcription initiation factor activity(GO:0016986)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.2	GO:0032451	demethylase activity(GO:0032451)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0030197	extracellular matrix constituent, lubricant activity(GO:0030197)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.1	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.2	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.0	GO:0019863	IgE binding(GO:0019863)
0.0	0.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.0	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity(GO:0047115)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0015377	cation:chloride symporter activity(GO:0015377)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.0	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.2	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.6	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
0.0	0.0	GO:0005000	vasopressin receptor activity(GO:0005000)
0.0	0.5	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0	0.1	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.0	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	1.1	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0	0.1	GO:0070717	poly(A) binding(GO:0008143) poly-purine tract binding(GO:0070717)
0.0	0.0	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.0	0.3	GO:0016830	carbon-carbon lyase activity(GO:0016830)
0.0	0.0	GO:0032129	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.0	0.1	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.0	0.0	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
1.1	PID EPO PATHWAY	EPO signaling pathway
1.2	PID INSULIN PATHWAY	Insulin Pathway
0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.5	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.2	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.3	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.6	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.7	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.5	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.4	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.7	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.4	PID ARF 3PATHWAY	Arf1 pathway
1.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.5	PID MYC PATHWAY	C-MYC pathway
0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.5	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	PID IFNG PATHWAY	IFN-gamma pathway
0.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.3	PID ATR PATHWAY	ATR signaling pathway
0.3	PID BARD1 PATHWAY	BARD1 signaling events
0.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	PID IL1 PATHWAY	IL1-mediated signaling events
0.4	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.4	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	PID BCR 5PATHWAY	BCR signaling pathway
0.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.6	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5	REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE	Genes involved in Reversible Hydration of Carbon Dioxide
0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.4	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.3	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
1.0	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.3	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
0.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.3	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.3	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.3	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.4	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.2	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.2	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
1.4	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.1	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.2	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.3	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.2	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.2	REACTOME PRE NOTCH EXPRESSION AND PROCESSING	Genes involved in Pre-NOTCH Expression and Processing
0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.2	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis

Results for KLF14_SP8

Z-value: 1.39

Motif logo

Transcription factors associated with KLF14_SP8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the KLF14_SP8 motif across conditions

Conditions sorted by the z-value of the KLF14_SP8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF14_SP8

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: