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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for KLF15

Z-value: 1.62

Motif logo

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Transcription factors associated with KLF15

Gene Symbol Gene ID Gene Info
KLF15
ENSG00000163884.3 KLF15

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
KLF15chr3_126076169_126076320410.977098-0.655.7e-02Click!
KLF15chr3_126074371_12607452218390.3489880.521.5e-01Click!
KLF15chr3_126006504_126006736696650.083828-0.393.0e-01Click!
KLF15chr3_126077020_1260771718100.633986-0.373.3e-01Click!
KLF15chr3_126006806_126006985693900.084266-0.255.2e-01Click!

Activity of the KLF15 motif across conditions

Conditions sorted by the z-value of the KLF15 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_219745650_219746144 1.07 WNT10A
 wingless-type MMTV integration site family, member 10A
 812
 0.5
chr9_130666902_130667485 1.03 ST6GALNAC6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 416
 0.68
chr9_130740055_130740787 0.90 FAM102A
 family with sequence similarity 102, member A
 2371
 0.18
chr16_86638278_86638465 0.81 FOXL1
 forkhead box L1
 26256
 0.16
chr1_111214730_111214881 0.78 KCNA3
 potassium voltage-gated channel, shaker-related subfamily, member 3
 2850
 0.25
chr6_41499474_41499746 0.71 RP11-328M4.2
14202
 0.17
chr16_80690406_80690960 0.69 ENSG00000265341
 .
 8777
 0.18
chr14_99738110_99739167 0.63 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 777
 0.68
chr19_872645_872938 0.63 CFD
 complement factor D (adipsin)
 13101
 0.07
chr13_99737560_99737956 0.63 DOCK9
 dedicator of cytokinesis 9
 902
 0.56
chr19_912362_912526 0.63 R3HDM4
 R3H domain containing 4
 787
 0.39
chr6_33589286_33590289 0.61 ITPR3
 inositol 1,4,5-trisphosphate receptor, type 3
 626
 0.65
chr9_130735011_130735162 0.60 FAM102A
 family with sequence similarity 102, member A
 7706
 0.11
chr11_67184651_67184869 0.60 CARNS1
 carnosine synthase 1
 1203
 0.21
chr12_6809262_6809475 0.58 PIANP
 PILR alpha associated neural protein
 213
 0.84
chr7_2561062_2561754 0.58 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 1912
 0.27
chr16_1257644_1257806 0.56 RP11-616M22.3
601
 0.54
chr11_68890438_68890903 0.55 RP11-554A11.9
32708
 0.15
chr12_103889445_103890055 0.51 C12orf42
 chromosome 12 open reading frame 42
 1
 0.99
chr10_5334923_5335219 0.51 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 4638
 0.23
chr9_33446798_33447442 0.51 AQP3
 aquaporin 3 (Gill blood group)
 489
 0.76
chr8_144102038_144102282 0.51 LY6E
 lymphocyte antigen 6 complex, locus E
 2186
 0.28
chr14_105944400_105944551 0.50 CRIP2
 cysteine-rich protein 2
 3320
 0.13
chr8_21906118_21906438 0.49 DMTN
 dematin actin binding protein
 228
 0.88
chr2_242801310_242801461 0.49 PDCD1
 programmed cell death 1
 325
 0.81
chr19_10346719_10347362 0.49 DNMT1
 DNA (cytosine-5-)-methyltransferase 1
 5078
 0.09
chr1_19253687_19254204 0.48 IFFO2
 intermediate filament family orphan 2
 15459
 0.16
chr22_39417668_39418190 0.47 APOBEC3D
 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
 472
 0.69
chr14_99736204_99736825 0.46 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 1051
 0.56
chrX_103216700_103217107 0.46 TMSB15B
 thymosin beta 15B
 311
 0.87
chr17_17696076_17696345 0.46 RAI1
 retinoic acid induced 1
 53
 0.96
chr16_28997019_28997515 0.45 LAT
 linker for activation of T cells
 266
 0.8
chr2_219745053_219745526 0.45 WNT10A
 wingless-type MMTV integration site family, member 10A
 204
 0.9
chr10_43761824_43761979 0.45 RASGEF1A
 RasGEF domain family, member 1A
 466
 0.86
chr12_55377292_55377444 0.44 TESPA1
 thymocyte expressed, positive selection associated 1
 1088
 0.58
chr14_99732558_99733007 0.44 AL109767.1
3497
 0.26
chr10_5295585_5295741 0.44 AKR1C7P
 aldo-keto reductase family 1, member C7, pseudogene
 34770
 0.13
chr11_45376699_45377561 0.43 SYT13
 synaptotagmin XIII
 69260
 0.12
chr14_99734743_99735157 0.43 BCL11B
 B-cell CLL/lymphoma 11B (zinc finger protein)
 2615
 0.3
chr16_1584614_1584961 0.43 TMEM204
 transmembrane protein 204
 1213
 0.24
chr21_46348074_46348493 0.43 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 350
 0.75
chr17_76117639_76118201 0.42 TMC6
 transmembrane channel-like 6
 909
 0.44
chr3_124303143_124303518 0.42 KALRN
 kalirin, RhoGEF kinase
 176
 0.97
chr8_145010242_145010727 0.42 PLEC
 plectin
 3274
 0.14
chr9_100337708_100338116 0.42 TMOD1
 tropomodulin 1
 20195
 0.16
chr20_62405735_62405886 0.41 ZBTB46
 zinc finger and BTB domain containing 46
 16337
 0.08
chr19_3176451_3176602 0.41 S1PR4
 sphingosine-1-phosphate receptor 4
 2210
 0.2
chr1_2347262_2347748 0.41 PEX10
 peroxisomal biogenesis factor 10
 2269
 0.17
chr1_20812630_20812781 0.40 CAMK2N1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
 8
 0.98
chr16_27417712_27417863 0.40 IL21R
 interleukin 21 receptor
 3364
 0.26
chr19_14142170_14142536 0.40 CTB-55O6.4
16
 0.71
chr5_167718925_167719411 0.40 WWC1
 WW and C2 domain containing 1
 13
 0.99
chr1_154981837_154981988 0.40 ZBTB7B
 zinc finger and BTB domain containing 7B
 5012
 0.08
chr17_74235537_74235688 0.40 RNF157
 ring finger protein 157
 770
 0.56
chr17_35860978_35861129 0.39 DUSP14
 dual specificity phosphatase 14
 8928
 0.19
chr19_42278518_42278669 0.39 AC011513.4
12208
 0.12
chr5_133451742_133452000 0.39 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 555
 0.8
chr21_45662097_45662248 0.39 ICOSLG
 inducible T-cell co-stimulator ligand
 1323
 0.3
chr6_167275533_167276547 0.38 RPS6KA2
 ribosomal protein S6 kinase, 90kDa, polypeptide 2
 1
 0.98
chr15_57998490_57998701 0.38 POLR2M
 polymerase (RNA) II (DNA directed) polypeptide M
 232
 0.96
chr11_61275416_61275567 0.38 ENSG00000266006
 .
 577
 0.5
chr1_32739634_32739785 0.38 LCK
 lymphocyte-specific protein tyrosine kinase
 5
 0.95
chr16_67184257_67184644 0.38 B3GNT9
 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
 667
 0.44
chr19_11248510_11248783 0.37 SPC24
 SPC24, NDC80 kinetochore complex component
 17791
 0.12
chr12_6883096_6883247 0.37 LAG3
 lymphocyte-activation gene 3
 1485
 0.18
chr9_135748688_135748839 0.37 C9orf9
 chromosome 9 open reading frame 9
 4651
 0.15
chr10_21823232_21823499 0.37 MLLT10
 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
 91
 0.96
chr9_89562965_89563269 0.37 GAS1
 growth arrest-specific 1
 1013
 0.71
chr8_124553811_124554260 0.36 FBXO32
 F-box protein 32
 589
 0.77
chr22_25817461_25817807 0.36 IGLVIVOR22-1
 immunoglobulin lambda variable (IV)/OR22-1 (pseudogene)
 16156
 0.16
chr1_156785806_156786457 0.36 SH2D2A
 SH2 domain containing 2A
 495
 0.51
chr12_49932560_49932732 0.36 KCNH3
 potassium voltage-gated channel, subfamily H (eag-related), member 3
 294
 0.87
chr11_118480521_118480750 0.35 PHLDB1
 pleckstrin homology-like domain, family B, member 1
 2277
 0.19
chr6_43422448_43423269 0.35 DLK2
 delta-like 2 homolog (Drosophila)
 470
 0.69
chr20_24929974_24930125 0.35 CST7
 cystatin F (leukocystatin)
 183
 0.95
chr7_99818085_99818479 0.35 ENSG00000222482
 .
 539
 0.54
chr1_10577315_10577466 0.35 PEX14
 peroxisomal biogenesis factor 14
 42351
 0.1
chr5_133861629_133862874 0.35 JADE2
 jade family PHD finger 2
 76
 0.97
chr1_9486266_9486417 0.35 ENSG00000252956
 .
 11496
 0.23
chr4_186063849_186064336 0.35 SLC25A4
 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
 303
 0.9
chr22_25201863_25202085 0.34 SGSM1
 small G protein signaling modulator 1
 262
 0.93
chr8_37553396_37553547 0.34 ZNF703
 zinc finger protein 703
 202
 0.91
chr12_48397374_48397525 0.34 COL2A1
 collagen, type II, alpha 1
 655
 0.62
chr10_71389637_71390649 0.34 C10orf35
 chromosome 10 open reading frame 35
 129
 0.97
chr11_118782043_118782381 0.34 BCL9L
 B-cell CLL/lymphoma 9-like
 599
 0.42
chr6_447061_447243 0.34 IRF4
 interferon regulatory factor 4
 55413
 0.15
chr2_23893302_23893453 0.34 KLHL29
 kelch-like family member 29
 28115
 0.24
chr22_38146169_38146320 0.34 TRIOBP
 TRIO and F-actin binding protein
 760
 0.52
chr17_47419551_47419937 0.33 ENSG00000251964
 .
 16481
 0.12
chr14_95981525_95981788 0.33 RP11-1070N10.3
 Uncharacterized protein
 817
 0.56
chr20_2802871_2803109 0.33 TMEM239
 transmembrane protein 239
 6011
 0.12
chr14_105527834_105528220 0.33 GPR132
 G protein-coupled receptor 132
 3740
 0.23
chr17_49021339_49022096 0.33 SPAG9
 sperm associated antigen 9
 49581
 0.11
chr1_205781878_205782029 0.33 SLC41A1
 solute carrier family 41 (magnesium transporter), member 1
 351
 0.86
chr7_99817647_99817839 0.33 ENSG00000222482
 .
 0
 0.92
chr7_3083277_3083584 0.33 CARD11
 caspase recruitment domain family, member 11
 49
 0.98
chr12_4140087_4140409 0.32 RP11-664D1.1
125862
 0.05
chr11_64510621_64511071 0.32 RASGRP2
 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
 415
 0.76
chr11_76381148_76381327 0.32 LRRC32
 leucine rich repeat containing 32
 193
 0.94
chr11_62312562_62314176 0.32 RP11-864I4.4
102
 0.64
chr19_3721754_3721946 0.32 TJP3
 tight junction protein 3
 115
 0.93
chr12_124422505_124422656 0.31 RP11-380L11.3
1827
 0.16
chr20_39766624_39767421 0.31 RP1-1J6.2
379
 0.79
chr19_14358666_14358817 0.31 ENSG00000240803
 .
 34877
 0.12
chr17_38717382_38717609 0.31 CCR7
 chemokine (C-C motif) receptor 7
 230
 0.92
chr9_130666481_130666789 0.31 ST6GALNAC6
 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
 974
 0.33
chr20_62368732_62368892 0.31 LIME1
 Lck interacting transmembrane adaptor 1
 175
 0.82
chr7_10980232_10980668 0.30 NDUFA4
 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa
 567
 0.81
chr16_50300120_50300376 0.30 ADCY7
 adenylate cyclase 7
 179
 0.96
chr17_47572677_47573321 0.30 NGFR
 nerve growth factor receptor
 344
 0.86
chr18_77283391_77284187 0.30 AC018445.1
 Uncharacterized protein
 7732
 0.29
chr15_81593030_81593311 0.30 IL16
 interleukin 16
 1413
 0.43
chr9_78507528_78507679 0.30 PCSK5
 proprotein convertase subtilisin/kexin type 5
 1982
 0.41
chr22_44577376_44577610 0.30 PARVG
 parvin, gamma
 215
 0.96
chrX_71003427_71003880 0.30 ENSG00000221684
 .
 24348
 0.23
chr20_42955224_42955721 0.30 R3HDML
 R3H domain containing-like
 10154
 0.11
chr8_21917643_21917901 0.30 DMTN
 dematin actin binding protein
 1038
 0.39
chr12_4917849_4918000 0.30 KCNA6
 potassium voltage-gated channel, shaker-related subfamily, member 6
 418
 0.85
chr14_105268498_105268649 0.30 ZBTB42
 zinc finger and BTB domain containing 42
 1323
 0.35
chr11_441689_441900 0.30 ANO9
 anoctamin 9
 217
 0.82
chr2_231280522_231280831 0.30 SP100
 SP100 nuclear antigen
 19
 0.98
chr7_142507018_142507186 0.30 PRSS3P2
 protease, serine, 3 pseudogene 2
 25971
 0.15
chr1_111746296_111746584 0.30 DENND2D
 DENN/MADD domain containing 2D
 591
 0.63
chr22_46828000_46828151 0.29 TRMU
 tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
 96256
 0.06
chr22_24823622_24823773 0.29 ADORA2A
 adenosine A2a receptor
 167
 0.95
chr3_150126449_150126853 0.29 TSC22D2
 TSC22 domain family, member 2
 529
 0.86
chr22_27067492_27067685 0.29 CRYBA4
 crystallin, beta A4
 49660
 0.13
chr19_2034669_2034820 0.29 AC007136.1
3694
 0.12
chr19_16438052_16438433 0.29 KLF2
 Kruppel-like factor 2
 2591
 0.21
chr19_41812650_41812801 0.29 CCDC97
 coiled-coil domain containing 97
 3369
 0.14
chr16_3115675_3115858 0.29 IL32
 interleukin 32
 19
 0.92
chr2_223288896_223289219 0.29 SGPP2
 sphingosine-1-phosphate phosphatase 2
 179
 0.95
chr2_240188602_240189192 0.29 ENSG00000265215
 .
 38260
 0.14
chr22_20146692_20146843 0.29 AC006547.14
 uncharacterized protein LOC388849
 8368
 0.1
chr18_24128407_24128977 0.29 KCTD1
 potassium channel tetramerization domain containing 1
 192
 0.96
chr1_228074699_228074927 0.28 ENSG00000264483
 .
 54571
 0.1
chr9_116916175_116916824 0.28 COL27A1
 collagen, type XXVII, alpha 1
 1341
 0.49
chr10_120788492_120789062 0.28 NANOS1
 nanos homolog 1 (Drosophila)
 451
 0.76
chrX_129220262_129220541 0.28 ELF4
 E74-like factor 4 (ets domain transcription factor)
 23935
 0.18
chr7_99764195_99764346 0.28 GAL3ST4
 galactose-3-O-sulfotransferase 4
 583
 0.47
chr17_72209755_72210280 0.28 TTYH2
 tweety family member 2
 364
 0.59
chr13_50705204_50705355 0.28 DLEU1
 deleted in lymphocytic leukemia 1 (non-protein coding)
 48972
 0.13
chr17_56033275_56033574 0.28 CUEDC1
 CUE domain containing 1
 740
 0.62
chr9_116139439_116139752 0.28 HDHD3
 haloacid dehalogenase-like hydrolase domain containing 3
 316
 0.84
chr22_26823969_26824219 0.27 ASPHD2
 aspartate beta-hydroxylase domain containing 2
 1145
 0.46
chr15_31653970_31654303 0.27 KLF13
 Kruppel-like factor 13
 4221
 0.35
chr2_235403849_235404784 0.27 ARL4C
 ADP-ribosylation factor-like 4C
 928
 0.74
chr10_80733781_80734431 0.27 ZMIZ1-AS1
 ZMIZ1 antisense RNA 1
 11955
 0.29
chr22_39638595_39638905 0.27 PDGFB
 platelet-derived growth factor beta polypeptide
 271
 0.89
chr1_160766939_160767112 0.27 LY9
 lymphocyte antigen 9
 1048
 0.51
chr12_54380133_54380310 0.27 RP11-834C11.12
592
 0.34
chr7_99950518_99950669 0.27 PILRB
 paired immunoglobin-like type 2 receptor beta
 59
 0.89
chr17_2699734_2700214 0.26 RAP1GAP2
 RAP1 GTPase activating protein 2
 198
 0.94
chr19_18386391_18386725 0.26 KIAA1683
 KIAA1683
 1239
 0.28
chr18_60823297_60823541 0.26 RP11-299P2.1
4866
 0.27
chr20_826059_826564 0.26 FAM110A
 family with sequence similarity 110, member A
 544
 0.82
chr13_30510013_30510639 0.26 LINC00572
 long intergenic non-protein coding RNA 572
 9538
 0.3
chr5_54400041_54400192 0.26 GZMA
 granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
 1640
 0.31
chr3_27763918_27764260 0.26 EOMES
 eomesodermin
 100
 0.98
chr17_79925387_79925672 0.26 NOTUM
 notum pectinacetylesterase homolog (Drosophila)
 5813
 0.07
chr5_133450980_133451278 0.26 TCF7
 transcription factor 7 (T-cell specific, HMG-box)
 125
 0.97
chr7_149996_150147 0.26 FAM20C
 family with sequence similarity 20, member C
 42898
 0.16
chr15_73344748_73345132 0.26 NEO1
 neogenin 1
 11
 0.99
chr13_113765266_113765417 0.26 F7
 coagulation factor VII (serum prothrombin conversion accelerator)
 5220
 0.13
chr10_105453143_105453834 0.26 SH3PXD2A
 SH3 and PX domains 2A
 558
 0.78
chr4_90227728_90227903 0.26 GPRIN3
 GPRIN family member 3
 1346
 0.6
chr2_204735072_204735223 0.26 CTLA4
 cytotoxic T-lymphocyte-associated protein 4
 192
 0.96
chr7_150413706_150414064 0.26 GIMAP1
 GTPase, IMAP family member 1
 240
 0.91
chr6_42391109_42391260 0.26 ENSG00000221252
 .
 11050
 0.21
chr12_51717169_51717830 0.25 BIN2
 bridging integrator 2
 400
 0.82
chr22_50919615_50920637 0.25 ADM2
 adrenomedullin 2
 27
 0.94
chr1_6550653_6550988 0.25 PLEKHG5
 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
 180
 0.92
chr10_64133612_64134509 0.25 ZNF365
 zinc finger protein 365
 109
 0.98
chr19_17958305_17958511 0.25 JAK3
 Janus kinase 3
 418
 0.74
chr12_53625173_53625934 0.25 RARG
 retinoic acid receptor, gamma
 405
 0.74
chr18_13273786_13273982 0.25 LDLRAD4
 low density lipoprotein receptor class A domain containing 4
 4218
 0.23
chr20_13200915_13201169 0.25 ISM1
 isthmin 1, angiogenesis inhibitor
 1376
 0.46
chr17_80274635_80275020 0.25 CD7
 CD7 molecule
 601
 0.6
chr9_123690633_123691433 0.25 TRAF1
 TNF receptor-associated factor 1
 14
 0.98
chr17_3866518_3867344 0.25 ATP2A3
 ATPase, Ca++ transporting, ubiquitous
 654
 0.71
chr14_22919447_22919600 0.25 TRDD3
 T cell receptor delta diversity 3
 1418
 0.27
chr16_88701814_88701965 0.25 IL17C
 interleukin 17C
 3112
 0.13
chr8_21906880_21907031 0.25 DMTN
 dematin actin binding protein
 295
 0.84
chr7_150327444_150327719 0.24 GIMAP6
 GTPase, IMAP family member 6
 1853
 0.35
chr9_140348775_140349192 0.24 NSMF
 NMDA receptor synaptonuclear signaling and neuronal migration factor
 39
 0.96
chr15_25200210_25200938 0.24 SNURF
 SNRPN upstream reading frame protein
 413
 0.41
chr12_56733576_56733727 0.24 IL23A
 interleukin 23, alpha subunit p19
 988
 0.29
chr21_45563966_45564117 0.24 C21orf33
 chromosome 21 open reading frame 33
 8040
 0.15
chr7_641876_642027 0.24 PRKAR1B
 protein kinase, cAMP-dependent, regulatory, type I, beta
 369
 0.73
chr17_72733506_72734386 0.24 RAB37
 RAB37, member RAS oncogene family
 575
 0.59
chr7_1704511_1705114 0.24 ELFN1
 extracellular leucine-rich repeat and fibronectin type III domain containing 1
 22943
 0.17
chr1_91188975_91189366 0.24 BARHL2
 BarH-like homeobox 2
 6376
 0.31
chr6_391719_392776 0.24 IRF4
 interferon regulatory factor 4
 508
 0.87
chr6_43243068_43244292 0.24 SLC22A7
 solute carrier family 22 (organic anion transporter), member 7
 22056
 0.11
chr19_49362125_49362344 0.24 PLEKHA4
 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
 397
 0.71
chr9_137347969_137348661 0.24 RXRA
 retinoid X receptor, alpha
 49887
 0.15
chr9_134147000_134147362 0.24 FAM78A
 family with sequence similarity 78, member A
 1271
 0.44
chr6_7107379_7107726 0.24 RREB1
 ras responsive element binding protein 1
 278
 0.93
chr22_39549404_39549636 0.24 CBX7
 chromobox homolog 7
 865
 0.57
chr7_5863704_5863864 0.24 ZNF815P
 zinc finger protein 815, pseudogene
 946
 0.54

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of KLF15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.6 GO:0072071 mesangial cell differentiation(GO:0072007) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) pericyte cell differentiation(GO:1904238)
0.2 1.2 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.1 0.4 GO:0070295 renal water absorption(GO:0070295)
0.1 0.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.7 GO:0070670 response to interleukin-4(GO:0070670)
0.1 0.4 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.4 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) acetylcholine secretion(GO:0061526)
0.1 0.3 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.3 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.1 0.5 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.4 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 0.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.3 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.1 0.3 GO:0015853 adenine transport(GO:0015853)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.1 0.2 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.1 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.1 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.1 0.5 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 0.1 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343)
0.1 0.3 GO:0015705 iodide transport(GO:0015705)
0.1 0.3 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.1 0.3 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.2 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.1 0.2 GO:0097205 regulation of glomerular filtration(GO:0003093) glomerular filtration(GO:0003094) renal filtration(GO:0097205) regulation of renal system process(GO:0098801)
0.1 0.2 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.1 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.2 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.1 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.2 GO:0071354 cellular response to interleukin-6(GO:0071354)
0.1 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272) embryonic skeletal joint development(GO:0072498)
0.1 0.2 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.1 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.1 0.2 GO:0097502 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.4 GO:0045577 regulation of B cell differentiation(GO:0045577)
0.0 0.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.0 0.2 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure(GO:0003071)
0.0 0.0 GO:0043173 nucleotide salvage(GO:0043173)
0.0 0.7 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.4 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367)
0.0 0.1 GO:0090047 obsolete positive regulation of transcription regulator activity(GO:0090047)
0.0 0.3 GO:0048641 regulation of skeletal muscle tissue development(GO:0048641)
0.0 0.1 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.1 GO:0035844 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.0 0.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.3 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.0 GO:0072162 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.0 GO:0003078 obsolete regulation of natriuresis(GO:0003078)
0.0 0.2 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654) positive regulation of hematopoietic progenitor cell differentiation(GO:1901534)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) negative regulation of anion transmembrane transport(GO:1903960) negative regulation of fatty acid transport(GO:2000192)
0.0 0.4 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.0 0.1 GO:0001821 histamine secretion(GO:0001821)
0.0 0.0 GO:0051590 positive regulation of neurotransmitter transport(GO:0051590)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.0 0.1 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.3 GO:0007520 syncytium formation by plasma membrane fusion(GO:0000768) myoblast fusion(GO:0007520)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) positive regulation of lamellipodium organization(GO:1902745)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.3 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.1 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.2 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.1 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.1 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0008356 asymmetric cell division(GO:0008356)
0.0 0.1 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.1 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0070828 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.1 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.0 0.1 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836) positive regulation of meiotic cell cycle(GO:0051446)
0.0 0.1 GO:0032367 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:0034616 response to laminar fluid shear stress(GO:0034616)
0.0 0.0 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0015793 glycerol transport(GO:0015793)
0.0 0.3 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546)
0.0 0.1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.1 GO:1901984 negative regulation of histone acetylation(GO:0035067) negative regulation of protein acetylation(GO:1901984) negative regulation of peptidyl-lysine acetylation(GO:2000757)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.1 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0007440 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.0 0.1 GO:0002068 glandular epithelial cell development(GO:0002068)
0.0 0.1 GO:0032528 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.0 0.0 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.1 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.2 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.0 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.0 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.0 GO:0042362 fat-soluble vitamin biosynthetic process(GO:0042362)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0040023 establishment of nucleus localization(GO:0040023)
0.0 0.2 GO:0042772 DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0 0.1 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.0 0.1 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.0 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.2 GO:0051496 positive regulation of stress fiber assembly(GO:0051496)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0002691 regulation of cellular extravasation(GO:0002691)
0.0 0.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.0 GO:0060242 contact inhibition(GO:0060242)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801)
0.0 0.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.0 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.0 GO:0003077 obsolete negative regulation of diuresis(GO:0003077)
0.0 0.1 GO:0042508 tyrosine phosphorylation of Stat1 protein(GO:0042508)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:1990748 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) cellular oxidant detoxification(GO:0098869) cellular detoxification(GO:1990748)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.0 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.0 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.1 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.0 0.2 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0039656 modulation by virus of host gene expression(GO:0039656)
0.0 0.1 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.0 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.0 GO:0072075 kidney mesenchyme development(GO:0072074) metanephric mesenchyme development(GO:0072075)
0.0 0.0 GO:0051971 positive regulation of transmission of nerve impulse(GO:0051971)
0.0 0.2 GO:1903078 positive regulation of establishment of protein localization to plasma membrane(GO:0090004) positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.8 GO:0031295 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.1 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 0.1 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.0 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.0 0.1 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.0 GO:0046137 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.1 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.0 GO:0039694 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0022601 menstrual cycle phase(GO:0022601)
0.0 0.0 GO:0032776 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0045080 positive regulation of chemokine biosynthetic process(GO:0045080)
0.0 0.0 GO:0050665 hydrogen peroxide biosynthetic process(GO:0050665)
0.0 0.0 GO:0007042 lysosomal lumen acidification(GO:0007042) regulation of lysosomal lumen pH(GO:0035751)
0.0 0.1 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.1 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.0 0.1 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.1 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.3 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.0 GO:0046471 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin metabolic process(GO:0032048) cardiolipin biosynthetic process(GO:0032049) phosphatidylglycerol metabolic process(GO:0046471)
0.0 0.0 GO:0060438 trachea development(GO:0060438)
0.0 0.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.0 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.0 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.0 GO:0009296 obsolete flagellum assembly(GO:0009296)
0.0 0.3 GO:0030593 neutrophil chemotaxis(GO:0030593) neutrophil migration(GO:1990266)
0.0 0.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.0 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.0 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.1 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0 0.0 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.3 GO:0019835 cytolysis(GO:0019835)
0.0 0.1 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.0 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.2 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.0 0.0 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.0 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0032429 regulation of phospholipase A2 activity(GO:0032429)
0.0 0.0 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.0 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:0051138 NK T cell differentiation(GO:0001865) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.0 0.2 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.3 GO:0007602 phototransduction(GO:0007602)
0.0 0.0 GO:0021542 dentate gyrus development(GO:0021542)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.2 GO:0006513 protein monoubiquitination(GO:0006513)
0.0 0.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0007100 mitotic centrosome separation(GO:0007100)
0.0 0.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.0 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.0 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0008615 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 metabolic process(GO:0042816) vitamin B6 biosynthetic process(GO:0042819)
0.0 0.0 GO:0051900 regulation of membrane depolarization(GO:0003254) regulation of mitochondrial depolarization(GO:0051900)
0.0 0.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.0 GO:0019987 obsolete negative regulation of anti-apoptosis(GO:0019987)
0.0 0.0 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.0 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.0 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.1 0.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.5 GO:0002102 podosome(GO:0002102)
0.1 0.7 GO:0001772 immunological synapse(GO:0001772)
0.1 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0031904 endosome lumen(GO:0031904)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0043260 laminin-11 complex(GO:0043260)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.3 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.6 GO:0005626 obsolete insoluble fraction(GO:0005626)
0.0 0.1 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.0 GO:0031312 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of organelle membrane(GO:0031312) extrinsic component of endosome membrane(GO:0031313)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.0 GO:0070820 tertiary granule(GO:0070820)
0.0 0.0 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)
0.0 0.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0071564 npBAF complex(GO:0071564)
0.0 0.0 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.3 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.1 GO:0005035 death receptor activity(GO:0005035)
0.1 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.3 GO:0015421 oligopeptide-transporting ATPase activity(GO:0015421)
0.1 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.4 GO:0005110 frizzled-2 binding(GO:0005110)
0.1 0.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0034187 obsolete apolipoprotein E binding(GO:0034187)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.2 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.3 GO:0030276 clathrin binding(GO:0030276)
0.0 0.2 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922)
0.0 0.5 GO:0051117 ATPase binding(GO:0051117)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0051635 obsolete bacterial cell surface binding(GO:0051635)
0.0 0.2 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0016595 glutamate binding(GO:0016595)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0004428 obsolete inositol or phosphatidylinositol kinase activity(GO:0004428)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.3 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 1.5 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0003840 gamma-glutamyltransferase activity(GO:0003840)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0019210 kinase inhibitor activity(GO:0019210)
0.0 0.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.0 GO:0004516 nicotinate phosphoribosyltransferase activity(GO:0004516)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.0 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0003701 obsolete RNA polymerase I transcription factor activity(GO:0003701)
0.0 0.0 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.3 GO:0003702 obsolete RNA polymerase II transcription factor activity(GO:0003702)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.0 0.0 GO:1901567 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.0 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.0 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 0.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 ST GAQ PATHWAY G alpha q Pathway
0.0 1.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.1 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.0 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 1.1 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.1 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.7 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.0 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.3 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.1 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.1 REACTOME SIGNALING BY NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.0 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism