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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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Results for KLF7

Z-value: 1.91

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Transcription factors associated with KLF7

Gene Symbol	Gene ID	Gene Info
KLF7 Ensembl NCBI GeneCards UniProt	ENSG00000118263.10	Kruppel like factor 7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_208006684_208006835	KLF7	7898	0.200545	-0.88	1.9e-03	Click!
chr2_208000784_208000935	KLF7	1998	0.329023	-0.78	1.3e-02	Click!
chr2_208000481_208000742	KLF7	1750	0.362101	-0.73	2.5e-02	Click!
chr2_208017651_208017818	KLF7	12561	0.197360	-0.69	4.1e-02	Click!
chr2_208029828_208030644	KLF7	59	0.978988	0.68	4.3e-02	Click!

Activity of the KLF7 motif across conditions

Conditions sorted by the z-value of the KLF7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_111415846_111416285	0.99	CD53	CD53 molecule	289	0.91
chrX_129218649_129218800	0.98	ELF4	E74-like factor 4 (ets domain transcription factor)	25612	0.18
chr18_43268798_43268949	0.95	SLC14A2	solute carrier family 14 (urea transporter), member 2	22766	0.16
chr2_151412976_151413127	0.84	RND3	Rho family GTPase 3	17526	0.31
chr6_47666951_47667231	0.82	GPR115	G protein-coupled receptor 115	802	0.64
chr8_1431231_1431382	0.77	DLGAP2	discs, large (Drosophila) homolog-associated protein 2	18226	0.28
chr17_7210033_7210519	0.75	EIF5A	eukaryotic translation initiation factor 5A	42	0.92
chr19_55765720_55766271	0.73	PPP6R1	protein phosphatase 6, regulatory subunit 1	1142	0.27
chr11_20178638_20179031	0.73	DBX1	developing brain homeobox 1	3036	0.31
chr11_73490222_73490495	0.73	MRPL48	mitochondrial ribosomal protein L48	8003	0.15
chr2_110970201_110970394	0.73	NPHP1	nephronophthisis 1 (juvenile)	7654	0.23
chr6_116600126_116600342	0.70	TSPYL1	TSPY-like 1	832	0.44
chr3_47050667_47050875	0.69	NBEAL2	neurobeachin-like 2	4000	0.22
chr14_105331028_105331307	0.69	CEP170B	centrosomal protein 170B	450	0.81
chr1_9713633_9713784	0.67	C1orf200	chromosome 1 open reading frame 200	936	0.49
chr15_66649119_66649300	0.66	TIPIN	TIMELESS interacting protein	155	0.92
chr2_74165845_74165996	0.65	DGUOK	deoxyguanosine kinase	11885	0.15
chr19_48111330_48111585	0.65	GLTSCR1	glioma tumor suppressor candidate region gene 1	4	0.97
chr12_113770815_113771205	0.65	SLC8B1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	258	0.91
chr17_37558067_37558428	0.64	CTB-131K11.1		201	0.65
chrX_92928498_92928999	0.63	NAP1L3	nucleosome assembly protein 1-like 3	181	0.61
chr14_50985374_50985525	0.63	MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	13741	0.17
chr5_156968041_156968238	0.62	AC106801.1		24833	0.14
chr3_33138761_33138999	0.62	GLB1	galactosidase, beta 1	158	0.84
chr6_45983691_45983842	0.62	CLIC5	chloride intracellular channel 5	180	0.95
chr4_83350861_83351264	0.61	HNRNPDL	heterogeneous nuclear ribonucleoprotein D-like	43	0.93
chr1_89989972_89990271	0.61	LRRC8B	leucine rich repeat containing 8 family, member B	274	0.94
chr2_16081463_16081614	0.60	MYCNOS	MYCN opposite strand	166	0.89
chr13_74339708_74339938	0.60	KLF12	Kruppel-like factor 12	229363	0.02
chr6_36164322_36164500	0.58	BRPF3	bromodomain and PHD finger containing, 3	110	0.88
chr9_132653009_132653160	0.58	FNBP1	formin binding protein 1	28505	0.14
chr8_79577906_79578162	0.57	ZC2HC1A	zinc finger, C2HC-type containing 1A	248	0.95
chr2_201577972_201578363	0.57	AOX1	aldehyde oxidase 1	50537	0.11
chr7_157072586_157072755	0.57	ENSG00000266453	.	25817	0.21
chr13_76334632_76334929	0.57	LMO7	LIM domain 7	15	0.99
chr6_25042448_25042685	0.56	FAM65B	family with sequence similarity 65, member B	328	0.63
chr1_26872331_26872899	0.56	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	272	0.88
chr10_105880540_105880741	0.56	SFR1	SWI5-dependent recombination repair 1	1176	0.46
chr16_69516663_69516814	0.56	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	58052	0.09
chr1_154315658_154315860	0.55	ENSG00000238365	.	4540	0.12
chr3_197476356_197476565	0.55	FYTTD1	forty-two-three domain containing 1	36	0.58
chr9_95727201_95727619	0.55	FGD3	FYVE, RhoGEF and PH domain containing 3	1167	0.54
chr16_22384493_22384879	0.55	CDR2	cerebellar degeneration-related protein 2, 62kDa	1252	0.31
chr11_112833488_112833639	0.54	RP11-629G13.1		619	0.65
chr11_65029483_65029818	0.54	POLA2	polymerase (DNA directed), alpha 2, accessory subunit	217	0.91
chr7_104584495_104584838	0.54	ENSG00000251911	.	27068	0.16
chr14_75990098_75990249	0.53	BATF	basic leucine zipper transcription factor, ATF-like	1270	0.47
chr12_62656333_62656484	0.53	USP15	ubiquitin specific peptidase 15	2199	0.3
chr17_33673306_33673493	0.53	SLFN11	schlafen family member 11	6751	0.2
chr12_53773389_53773606	0.52	SP1	Sp1 transcription factor	463	0.73
chr1_109757024_109757692	0.52	SARS	seryl-tRNA synthetase	754	0.58
chr3_57677289_57677722	0.52	DENND6A	DENN/MADD domain containing 6A	1311	0.4
chr21_42741228_42741619	0.51	MX2	myxovirus (influenza virus) resistance 2 (mouse)	589	0.77
chr9_73026582_73027022	0.51	KLF9	Kruppel-like factor 9	2738	0.37
chr2_96657272_96657655	0.51	ANKRD36C	ankyrin repeat domain 36C	78	0.97
chr12_113494960_113495179	0.51	DTX1	deltex homolog 1 (Drosophila)	426	0.82
chr2_85153190_85153512	0.51	TMSB10	thymosin beta 10	20602	0.17
chr3_111260963_111261300	0.51	CD96	CD96 molecule	134	0.97
chr8_8203302_8203453	0.51	SGK223	Tyrosine-protein kinase SgK223	35880	0.18
chr12_133083604_133083856	0.50	FBRSL1	fibrosin-like 1	16573	0.19
chr3_9690857_9691008	0.50	MTMR14	myotubularin related protein 14	185	0.94
chr16_86638626_86639076	0.49	FOXL1	forkhead box L1	26736	0.16
chr11_73692681_73692970	0.49	UCP2	uncoupling protein 2 (mitochondrial, proton carrier)	842	0.53
chr10_134716551_134716702	0.49	TTC40	tetratricopeptide repeat domain 40	39463	0.18
chr6_89790098_89790249	0.49	RP11-63L7.5		213	0.59
chr6_36973743_36974036	0.49	FGD2	FYVE, RhoGEF and PH domain containing 2	466	0.8
chr2_46524572_46524838	0.49	EPAS1	endothelial PAS domain protein 1	164	0.97
chr1_249131820_249131984	0.49	ZNF672	zinc finger protein 672	577	0.67
chr4_185182739_185182890	0.48	ENSG00000221523	.	5770	0.22
chr5_67510861_67511301	0.48	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	467	0.86
chr2_207115371_207115541	0.48	ENSG00000252716	.	9482	0.15
chr8_133787726_133787926	0.47	PHF20L1	PHD finger protein 20-like 1	0	0.98
chr13_101169809_101169960	0.47	PCCA	propionyl CoA carboxylase, alpha polypeptide	2203	0.29
chr14_103010712_103010863	0.47	ENSG00000266015	.	4806	0.19
chr5_159846201_159846839	0.47	SLU7	SLU7 splicing factor homolog (S. cerevisiae)	119	0.95
chr15_65282464_65282690	0.47	SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	71	0.97
chr6_4136387_4136965	0.47	ECI2	enoyl-CoA delta isomerase 2	845	0.44
chr9_139433085_139433378	0.46	RP11-413M3.4		4102	0.11
chr12_14518654_14518864	0.46	ATF7IP	activating transcription factor 7 interacting protein	96	0.98
chr9_33001711_33002097	0.46	APTX	aprataxin	265	0.91
chr3_150479775_150480371	0.46	SIAH2-AS1	SIAH2 antisense RNA 1	349	0.79
chr15_81426280_81426524	0.46	C15orf26	chromosome 15 open reading frame 26	186	0.96
chr5_36876188_36876410	0.46	NIPBL	Nipped-B homolog (Drosophila)	562	0.86
chr10_8068775_8069028	0.46	GATA3	GATA binding protein 3	27755	0.26
chr11_62308687_62309106	0.46	RP11-864I4.3		4112	0.1
chr11_62647941_62648236	0.45	SLC3A2	solute carrier family 3 (amino acid transporter heavy chain), member 2	194	0.87
chr22_38793180_38793744	0.45	CSNK1E	casein kinase 1, epsilon	1065	0.4
chr18_33530285_33530492	0.45	ENSG00000265641	.	16283	0.17
chr5_90576543_90576733	0.44	ENSG00000199643	.	10094	0.28
chr2_74710229_74710420	0.44	CCDC142	coiled-coil domain containing 142	37	0.56
chr9_130733348_130733499	0.44	FAM102A	family with sequence similarity 102, member A	9369	0.11
chr19_15580698_15580960	0.43	RASAL3	RAS protein activator like 3	5447	0.13
chr12_52463075_52463333	0.43	C12orf44	chromosome 12 open reading frame 44	551	0.63
chr6_33239851_33240264	0.43	RPS18	ribosomal protein S18	205	0.61
chr22_31031104_31031465	0.43	SLC35E4	solute carrier family 35, member E4	355	0.81
chr2_70314282_70314484	0.43	PCBP1-AS1	PCBP1 antisense RNA 1	53	0.7
chr12_31226828_31227064	0.43	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11	114	0.57
chr12_120428180_120428604	0.43	CCDC64	coiled-coil domain containing 64	719	0.72
chr19_6590606_6591184	0.43	CD70	CD70 molecule	255	0.89
chr17_3289151_3289302	0.43	RP11-64J4.2		361	0.82
chr4_2801611_2801762	0.43	SH3BP2	SH3-domain binding protein 2	961	0.59
chr1_26646074_26646278	0.42	UBXN11	UBX domain protein 11	1322	0.27
chr17_76109268_76109419	0.42	ENSG00000204282	.	1463	0.29
chr7_27200041_27200697	0.42	HOXA7	homeobox A7	2814	0.08
chr16_79630640_79632238	0.42	MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	2360	0.43
chr6_35267446_35267597	0.41	DEF6	differentially expressed in FDCP 6 homolog (mouse)	1892	0.32
chr6_33539685_33539836	0.41	BAK1	BCL2-antagonist/killer 1	8221	0.13
chr3_32442741_32443149	0.41	CMTM7	CKLF-like MARVEL transmembrane domain containing 7	9414	0.25
chr11_726415_726634	0.41	AP006621.9		523	0.57
chr15_50004365_50004516	0.41	RP11-353B9.1		60104	0.12
chr13_22178024_22178253	0.41	MICU2	mitochondrial calcium uptake 2	182	0.96
chr19_17590091_17590333	0.40	SLC27A1	solute carrier family 27 (fatty acid transporter), member 1	8914	0.08
chr19_46172257_46172467	0.40	GIPR	gastric inhibitory polypeptide receptor	847	0.37
chr1_205819043_205819299	0.40	PM20D1	peptidase M20 domain containing 1	74	0.97
chr19_51522437_51522588	0.40	KLK10	kallikrein-related peptidase 10	508	0.54
chrX_45709671_45710004	0.40	ENSG00000212347	.	42577	0.19
chr19_17622094_17622308	0.40	PGLS	6-phosphogluconolactonase	237	0.85
chr15_75199296_75199599	0.40	FAM219B	family with sequence similarity 219, member B	15	0.96
chr17_8089749_8090065	0.40	ENSG00000266638	.	586	0.5
chr15_41047576_41047750	0.39	RMDN3	regulator of microtubule dynamics 3	129	0.93
chr10_102588726_102589022	0.39	ENSG00000222072	.	78163	0.07
chr19_2775817_2776209	0.39	SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	5234	0.12
chr4_56719874_56720283	0.39	EXOC1	exocyst complex component 1	173	0.95
chr10_124135009_124135427	0.39	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	868	0.6
chr2_74881058_74881259	0.39	SEMA4F	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F	197	0.93
chr6_116597784_116598857	0.39	TSPYL1	TSPY-like 1	2746	0.21
chr10_111986414_111986565	0.39	MXI1	MAX interactor 1, dimerization protein	647	0.75
chr10_12110997_12111197	0.39	DHTKD1	dehydrogenase E1 and transketolase domain containing 1	74	0.97
chr12_9436279_9436529	0.39	ENSG00000212440	.	3014	0.25
chr11_117860694_117860845	0.38	IL10RA	interleukin 10 receptor, alpha	3660	0.23
chr1_49242712_49243015	0.38	BEND5	BEN domain containing 5	273	0.95
chr10_97667704_97667951	0.38	C10orf131	chromosome 10 open reading frame 131	105	0.62
chr11_72853974_72854211	0.38	FCHSD2	FCH and double SH3 domains 2	786	0.69
chr1_26231368_26231927	0.38	STMN1	stathmin 1	28	0.94
chr17_13241369_13241749	0.38	ENSG00000266115	.	162086	0.04
chr1_173793809_173794356	0.38	DARS2	aspartyl-tRNA synthetase 2, mitochondrial	285	0.7
chr1_154927193_154927621	0.38	PBXIP1	pre-B-cell leukemia homeobox interacting protein 1	1173	0.25
chr8_8746534_8747046	0.37	MFHAS1	malignant fibrous histiocytoma amplified sequence 1	4365	0.23
chr19_49403923_49404430	0.37	NUCB1	nucleobindin 1	121	0.9
chr14_100704060_100704316	0.37	YY1	YY1 transcription factor	447	0.56
chr5_72251288_72251681	0.37	FCHO2	FCH domain only 2	324	0.92
chrX_154285608_154285801	0.37	CMC4	C-x(9)-C motif containing 4	7939	0.14
chr1_26561482_26561883	0.37	CEP85	centrosomal protein 85kDa	989	0.41
chrX_80457617_80458353	0.37	SH3BGRL	SH3 domain binding glutamic acid-rich protein like	543	0.46
chr8_23075544_23076103	0.37	ENSG00000246582	.	6161	0.12
chr17_33814121_33814953	0.36	SLFN12L	schlafen family member 12-like	316	0.84
chr7_150373814_150373965	0.36	GIMAP2	GTPase, IMAP family member 2	8899	0.17
chr3_56591241_56591766	0.36	CCDC66	coiled-coil domain containing 66	287	0.94
chr12_4381277_4381428	0.36	CCND2	cyclin D2	1586	0.32
chr10_43133374_43133621	0.36	ZNF33B	zinc finger protein 33B	495	0.85
chr9_130736775_130737070	0.36	FAM102A	family with sequence similarity 102, member A	5870	0.12
chr8_128806891_128807842	0.36	ENSG00000249859	.	842	0.72
chr14_64107873_64108536	0.36	WDR89	WD repeat domain 89	79	0.96
chr6_144385545_144385940	0.36	PLAGL1	pleiomorphic adenoma gene-like 1	7	0.98
chr6_26597613_26597959	0.36	ABT1	activator of basal transcription 1	606	0.73
chr7_150070289_150070440	0.36	RP4-584D14.5		685	0.5
chrX_129245186_129245676	0.35	ELF4	E74-like factor 4 (ets domain transcription factor)	740	0.69
chr20_44486283_44486492	0.35	ZSWIM3	zinc finger, SWIM-type containing 3	131	0.72
chr5_99228364_99228515	0.35	ENSG00000199378	.	129069	0.06
chr17_4709881_4710063	0.35	PLD2	phospholipase D2	419	0.67
chr4_24584331_24584482	0.35	DHX15	DEAH (Asp-Glu-Ala-His) box helicase 15	1767	0.4
chr5_74348140_74348479	0.35	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	21585	0.25
chr14_57046740_57047215	0.35	TMEM260	transmembrane protein 260	375	0.91
chr13_53226532_53226731	0.35	SUGT1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	343	0.9
chr14_21131236_21131389	0.35	ENSG00000199461	.	16258	0.09
chr8_9008533_9008971	0.35	PPP1R3B	protein phosphatase 1, regulatory subunit 3B	332	0.62
chr1_147807090_147807347	0.35	ENSG00000202408	.	332	0.85
chrX_149860911_149861411	0.35	MTMR1	myotubularin related protein 1	274	0.95
chr16_9184823_9185042	0.35	C16orf72	chromosome 16 open reading frame 72	573	0.72
chr6_137540064_137540505	0.34	IFNGR1	interferon gamma receptor 1	215	0.96
chr22_32366297_32366691	0.34	ENSG00000240647	.	10920	0.14
chr16_11438920_11439177	0.34	RP11-485G7.5		6	0.75
chr22_38349726_38350087	0.34	POLR2F	polymerase (RNA) II (DNA directed) polypeptide F	172	0.56
chr17_46115604_46115869	0.34	COPZ2	coatomer protein complex, subunit zeta 2	344	0.7
chr17_72734396_72734547	0.34	RAB37	RAB37, member RAS oncogene family	1100	0.33
chr12_104851638_104851843	0.34	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	961	0.68
chr19_46171751_46172236	0.34	GIPR	gastric inhibitory polypeptide receptor	478	0.61
chr4_109087549_109087740	0.34	LEF1	lymphoid enhancer-binding factor 1	187	0.91
chr20_31330734_31331002	0.34	COMMD7	COMM domain containing 7	344	0.88
chr9_276345_276496	0.34	DOCK8	dedicator of cytokinesis 8	3350	0.24
chr22_43411396_43411716	0.34	PACSIN2	protein kinase C and casein kinase substrate in neurons 2	405	0.85
chr20_32262337_32262536	0.34	RP1-63M2.5		113	0.56
chr17_45811310_45811575	0.34	TBX21	T-box 21	832	0.55
chr17_21454142_21454502	0.34	C17orf51	chromosome 17 open reading frame 51	621	0.75
chr5_54830989_54831249	0.34	PPAP2A	phosphatidic acid phosphatase type 2A	241	0.94
chr2_43037752_43038106	0.34	HAAO	3-hydroxyanthranilate 3,4-dioxygenase	18197	0.23
chr2_192176235_192176432	0.34	MYO1B	myosin IB	34722	0.2
chrX_130912849_130913434	0.34	ENSG00000200587	.	159843	0.04
chr7_99647395_99647894	0.34	ZSCAN21	zinc finger and SCAN domain containing 21	227	0.84
chr20_5731235_5731458	0.33	C20orf196	chromosome 20 open reading frame 196	247	0.95
chr16_2317361_2317547	0.33	RNPS1	RNA binding protein S1, serine-rich domain	116	0.77
chr16_72127792_72128009	0.33	DHX38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	77	0.57
chr6_106546757_106547354	0.33	PRDM1	PR domain containing 1, with ZNF domain	240	0.87
chr17_37025636_37026147	0.33	LASP1	LIM and SH3 protein 1	221	0.86
chr1_12128033_12128184	0.33	TNFRSF8	tumor necrosis factor receptor superfamily, member 8	4581	0.16
chr22_39640196_39640514	0.33	PDGFB	platelet-derived growth factor beta polypeptide	401	0.8
chr15_67547384_67547573	0.33	AAGAB	alpha- and gamma-adaptin binding protein	55	0.81
chr19_7694674_7695267	0.33	PET100	PET100 homolog (S. cerevisiae)	260	0.65
chr20_61437961_61438112	0.33	OGFR	opioid growth factor receptor	589	0.53
chr19_45251774_45251925	0.33	BCL3	B-cell CLL/lymphoma 3	45	0.96

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.2	0.7	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.2	0.7	GO:0002093	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.2	0.5	GO:0071481	cellular response to X-ray(GO:0071481)
0.2	0.9	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1	0.4	GO:0030223	neutrophil differentiation(GO:0030223)
0.1	0.4	GO:0010040	response to iron(II) ion(GO:0010040)
0.1	0.6	GO:0001675	acrosome assembly(GO:0001675)
0.1	0.4	GO:0015801	aromatic amino acid transport(GO:0015801)
0.1	0.6	GO:0042989	sequestering of actin monomers(GO:0042989)
0.1	0.4	GO:0042091	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1	0.2	GO:0090382	phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1	0.3	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.1	0.3	GO:0051832	evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1	0.3	GO:0010533	regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1	0.4	GO:0006422	aspartyl-tRNA aminoacylation(GO:0006422)
0.1	0.4	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	0.2	GO:0032928	regulation of superoxide anion generation(GO:0032928)
0.1	0.3	GO:0040016	embryonic cleavage(GO:0040016)
0.1	0.3	GO:0001743	optic placode formation(GO:0001743)
0.1	0.4	GO:0048625	myoblast fate commitment(GO:0048625)
0.1	0.2	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1	0.2	GO:0002678	positive regulation of chronic inflammatory response(GO:0002678)
0.1	0.1	GO:0051132	NK T cell activation(GO:0051132)
0.1	0.2	GO:2000330	T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1	0.4	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.4	GO:0001866	NK T cell proliferation(GO:0001866)
0.1	0.3	GO:0050651	dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1	0.3	GO:0031427	response to methotrexate(GO:0031427)
0.1	0.2	GO:0016559	peroxisome fission(GO:0016559)
0.1	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1	0.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.1	0.4	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.1	0.2	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1	0.3	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.1	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.1	0.2	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.1	0.2	GO:0071569	protein ufmylation(GO:0071569)
0.1	0.2	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.1	GO:0042661	regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.1	0.4	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.1	0.2	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.1	0.2	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1	0.3	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.1	0.4	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.1	0.3	GO:0002063	chondrocyte development(GO:0002063)
0.1	0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.1	0.2	GO:0043320	natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1	0.4	GO:0001991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.1	0.2	GO:0021563	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1	0.2	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1	0.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1	0.2	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.2	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.4	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0072385	minus-end-directed organelle transport along microtubule(GO:0072385)
0.0	0.2	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0017085	response to insecticide(GO:0017085)
0.0	0.1	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0010823	negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0	0.2	GO:0031943	regulation of glucocorticoid metabolic process(GO:0031943)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.2	GO:0043302	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.2	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0030011	maintenance of cell polarity(GO:0030011)
0.0	0.1	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0006390	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.0	0.2	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0031053	primary miRNA processing(GO:0031053)
0.0	0.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.0	0.3	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0	0.3	GO:0007063	regulation of sister chromatid cohesion(GO:0007063)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.3	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.8	GO:0000722	telomere maintenance via recombination(GO:0000722)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.1	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.2	GO:0015840	urea transport(GO:0015840)
0.0	0.1	GO:0009106	lipoate metabolic process(GO:0009106)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0050961	detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.2	GO:0032350	regulation of hormone metabolic process(GO:0032350)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.2	GO:0010507	negative regulation of autophagy(GO:0010507)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.2	GO:0070301	cellular response to hydrogen peroxide(GO:0070301)
0.0	0.1	GO:0048670	regulation of collateral sprouting(GO:0048670)
0.0	0.4	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.4	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.4	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.8	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.3	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.2	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0	0.2	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.3	GO:0098534	centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0	0.5	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0050685	positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0	0.1	GO:0000422	mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0	0.1	GO:0000394	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.1	GO:0006930	substrate-dependent cell migration, cell extension(GO:0006930)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.2	GO:0072087	renal vesicle development(GO:0072087)
0.0	0.4	GO:0008593	regulation of Notch signaling pathway(GO:0008593)
0.0	0.0	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.0	0.1	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.0	0.7	GO:0006829	zinc II ion transport(GO:0006829)
0.0	0.2	GO:0046839	phospholipid dephosphorylation(GO:0046839)
0.0	0.1	GO:1903579	negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0008612	peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0	0.2	GO:0050718	positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0	0.1	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.9	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0	0.1	GO:0010956	negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:2000398	regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.3	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.3	GO:0034620	endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0	0.4	GO:0060330	regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0	0.3	GO:0001706	endoderm formation(GO:0001706)
0.0	0.7	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.1	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:0051957	positive regulation of amino acid transport(GO:0051957)
0.0	0.2	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0	0.1	GO:0060263	regulation of respiratory burst(GO:0060263)
0.0	0.1	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0	0.1	GO:0009158	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0046629	gamma-delta T cell activation(GO:0046629)
0.0	0.4	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.1	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	0.1	GO:0046149	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0	0.1	GO:0031641	regulation of myelination(GO:0031641)
0.0	0.4	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0035308	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0060396	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.2	GO:0045909	positive regulation of vasodilation(GO:0045909)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0001782	B cell homeostasis(GO:0001782)
0.0	0.2	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.4	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0	0.2	GO:0043029	T cell homeostasis(GO:0043029)
0.0	0.1	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.0	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.0	0.1	GO:0002360	T cell lineage commitment(GO:0002360)
0.0	0.0	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0071168	protein localization to chromatin(GO:0071168)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.2	GO:0000303	response to superoxide(GO:0000303)
0.0	0.0	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.3	GO:0042994	cytoplasmic sequestering of transcription factor(GO:0042994)
0.0	0.1	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.0	0.2	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.2	GO:0006896	Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.2	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.0	0.1	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.0	GO:0097300	necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0	0.1	GO:0045059	positive thymic T cell selection(GO:0045059)
0.0	0.0	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.0	GO:0030910	olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0	0.1	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.3	GO:0007062	sister chromatid cohesion(GO:0007062)
0.0	0.1	GO:0006346	methylation-dependent chromatin silencing(GO:0006346)
0.0	0.1	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0	0.0	GO:0010761	fibroblast migration(GO:0010761)
0.0	0.1	GO:1901021	positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0	0.2	GO:0006596	polyamine biosynthetic process(GO:0006596)
0.0	0.2	GO:0002029	desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0	0.1	GO:0007184	SMAD protein import into nucleus(GO:0007184)
0.0	0.0	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0050667	homocysteine metabolic process(GO:0050667)
0.0	0.2	GO:0016236	macroautophagy(GO:0016236)
0.0	0.1	GO:0071108	protein K48-linked deubiquitination(GO:0071108)
0.0	0.1	GO:0009405	pathogenesis(GO:0009405)
0.0	0.4	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.0	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.1	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0	0.0	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0031648	protein destabilization(GO:0031648)
0.0	0.1	GO:0051926	negative regulation of calcium ion transport(GO:0051926)
0.0	0.1	GO:0014037	Schwann cell differentiation(GO:0014037)
0.0	0.2	GO:0044550	secondary metabolite biosynthetic process(GO:0044550)
0.0	0.1	GO:0043247	telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.0	GO:0000768	syncytium formation by plasma membrane fusion(GO:0000768)
0.0	0.1	GO:0030149	sphingolipid catabolic process(GO:0030149)
0.0	0.0	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.2	GO:0007096	regulation of exit from mitosis(GO:0007096)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.2	GO:0006386	transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0	0.3	GO:0032006	regulation of TOR signaling(GO:0032006)
0.0	0.1	GO:0045749	obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0	0.5	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.4	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
0.0	0.1	GO:0042987	amyloid precursor protein catabolic process(GO:0042987)
0.0	0.4	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.1	GO:0021591	ventricular system development(GO:0021591)
0.0	0.0	GO:0021569	rhombomere 3 development(GO:0021569)
0.0	0.0	GO:0031223	auditory behavior(GO:0031223)
0.0	0.1	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.1	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	0.4	GO:0009395	phospholipid catabolic process(GO:0009395)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
0.0	0.0	GO:0007144	female meiosis I(GO:0007144)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.0	GO:0001661	conditioned taste aversion(GO:0001661)
0.0	0.0	GO:0000731	DNA synthesis involved in DNA repair(GO:0000731)
0.0	0.0	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0	0.1	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.0	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	0.0	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.2	GO:0050850	positive regulation of calcium-mediated signaling(GO:0050850)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.0	GO:0046931	pore complex assembly(GO:0046931)
0.0	0.1	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	1.3	GO:0006334	nucleosome assembly(GO:0006334)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	1.0	GO:0051028	mRNA transport(GO:0051028)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.0	GO:0060997	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0031113	regulation of microtubule polymerization(GO:0031113)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.3	GO:0014047	glutamate secretion(GO:0014047)
0.0	0.0	GO:0070234	positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.2	GO:0019674	NAD metabolic process(GO:0019674)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.0	GO:0010980	regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0	0.1	GO:0007031	peroxisome organization(GO:0007031)
0.0	0.0	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.0	0.0	GO:0021783	facial nerve development(GO:0021561) preganglionic parasympathetic fiber development(GO:0021783)
0.0	0.2	GO:0045814	negative regulation of gene expression, epigenetic(GO:0045814)
0.0	0.0	GO:0061047	positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0	0.2	GO:0007632	visual behavior(GO:0007632)
0.0	0.0	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.0	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
0.0	0.0	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.1	GO:0000012	single strand break repair(GO:0000012)
0.0	0.1	GO:0016446	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0	0.0	GO:0008628	hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0	0.2	GO:0033209	tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0	0.0	GO:0000266	mitochondrial fission(GO:0000266)
0.0	0.0	GO:0052555	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0	0.1	GO:0019682	pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0045010	actin nucleation(GO:0045010)
0.0	0.3	GO:0007569	cell aging(GO:0007569)
0.0	1.3	GO:0006184	obsolete GTP catabolic process(GO:0006184)
0.0	0.1	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0021522	spinal cord motor neuron differentiation(GO:0021522)
0.0	0.2	GO:0048536	spleen development(GO:0048536)
0.0	0.3	GO:0042147	retrograde transport, endosome to Golgi(GO:0042147)
0.0	0.1	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.2	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.0	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.1	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0051955	regulation of amino acid transport(GO:0051955)
0.0	0.1	GO:0016925	protein sumoylation(GO:0016925)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.0	0.5	GO:0006826	iron ion transport(GO:0006826)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	0.5	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1	0.3	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.2	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.1	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1	0.3	GO:0042587	glycogen granule(GO:0042587)
0.1	0.4	GO:0005678	obsolete chromatin assembly complex(GO:0005678)
0.1	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	0.8	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.1	0.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.1	0.5	GO:0000145	exocyst(GO:0000145)
0.1	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	0.4	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.7	GO:0000299	obsolete integral to membrane of membrane fraction(GO:0000299)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.2	GO:0005883	neurofilament(GO:0005883)
0.0	0.3	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.3	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0030904	retromer complex(GO:0030904)
0.0	0.4	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.5	GO:0032420	stereocilium(GO:0032420)
0.0	0.1	GO:0005766	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	1.6	GO:0016605	PML body(GO:0016605)
0.0	0.2	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0070062	extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0031933	telomeric heterochromatin(GO:0031933)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0032391	photoreceptor connecting cilium(GO:0032391)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.0	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.2	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0042827	platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.0	2.2	GO:0016607	nuclear speck(GO:0016607)
0.0	0.3	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.4	GO:0005689	U12-type spliceosomal complex(GO:0005689)
0.0	1.2	GO:0005643	nuclear pore(GO:0005643)
0.0	0.2	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.1	GO:0030894	replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0000781	chromosome, telomeric region(GO:0000781)
0.0	0.3	GO:0031519	PcG protein complex(GO:0031519)
0.0	0.9	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.2	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.2	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.0	0.2	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.0	GO:0008540	proteasome regulatory particle, base subcomplex(GO:0008540)
0.0	0.7	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.9	GO:0000776	kinetochore(GO:0000776)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.1	GO:0070695	FHF complex(GO:0070695)
0.0	0.9	GO:0032993	protein-DNA complex(GO:0032993)
0.0	0.5	GO:0005814	centriole(GO:0005814)
0.0	0.2	GO:0030137	COPI-coated vesicle(GO:0030137)
0.0	0.1	GO:0030686	90S preribosome(GO:0030686)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	1.0	GO:0030027	lamellipodium(GO:0030027)
0.0	0.5	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0000407	pre-autophagosomal structure(GO:0000407) pre-autophagosomal structure membrane(GO:0034045)
0.0	0.1	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.0	2.6	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	1.1	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0032449	CBM complex(GO:0032449)
0.0	0.0	GO:0045277	mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	2.9	GO:0000323	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.3	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.3	GO:0031902	late endosome membrane(GO:0031902)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.1	GO:1902555	endoribonuclease complex(GO:1902555)
0.0	0.1	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.0	GO:0033185	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.4	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0017070	U6 snRNA binding(GO:0017070)
0.1	0.6	GO:0015925	galactosidase activity(GO:0015925)
0.1	0.4	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.1	0.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.5	GO:0036002	pre-mRNA binding(GO:0036002)
0.1	0.4	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.6	GO:0004904	interferon receptor activity(GO:0004904)
0.1	0.3	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.1	0.3	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.1	0.4	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	0.4	GO:0004815	aspartate-tRNA ligase activity(GO:0004815)
0.1	0.3	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1	0.5	GO:0034452	dynactin binding(GO:0034452)
0.1	0.2	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1	0.3	GO:0030284	estrogen receptor activity(GO:0030284)
0.1	0.3	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.2	GO:0004911	interleukin-2 receptor activity(GO:0004911)
0.1	0.4	GO:0052813	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.2	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.1	0.3	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	0.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1	0.2	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.1	0.4	GO:0070087	chromo shadow domain binding(GO:0070087)
0.1	0.3	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.1	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0019211	phosphatase activator activity(GO:0019211)
0.1	0.2	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1	0.2	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1	0.4	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.1	0.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.5	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1	0.4	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1	0.8	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	0.3	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.5	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.2	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.1	GO:0016748	succinyltransferase activity(GO:0016748)
0.0	0.2	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.6	GO:0052866	phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0	0.2	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.1	GO:0031177	phosphopantetheine binding(GO:0031177)
0.0	0.3	GO:0061659	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0055103	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.3	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.2	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0	0.4	GO:0005112	Notch binding(GO:0005112)
0.0	0.2	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.3	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.2	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.2	GO:0016847	1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0	0.0	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0004607	phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0	0.2	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.9	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.2	GO:0005521	lamin binding(GO:0005521)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0090079	translation regulator activity, nucleic acid binding(GO:0090079)
0.0	0.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0010340	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0	0.1	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.3	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.5	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	1.3	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.0	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.3	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.2	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.1	GO:0099602	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.1	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.4	GO:0016790	thiolester hydrolase activity(GO:0016790)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.2	GO:0017069	snRNA binding(GO:0017069)
0.0	0.1	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0	0.2	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.0	GO:0070215	obsolete MDM2 binding(GO:0070215)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.4	GO:0043499	obsolete eukaryotic cell surface binding(GO:0043499)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.1	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.3	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0045569	TRAIL binding(GO:0045569)
0.0	0.6	GO:0002020	protease binding(GO:0002020)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.4	GO:0019843	rRNA binding(GO:0019843)
0.0	0.1	GO:0046979	TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.1	GO:0008035	high-density lipoprotein particle binding(GO:0008035)
0.0	0.5	GO:0003724	RNA helicase activity(GO:0003724)
0.0	0.2	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.2	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.1	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.4	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.0	GO:0016362	activin receptor activity, type II(GO:0016362)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0016413	O-acetyltransferase activity(GO:0016413)
0.0	0.3	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.1	GO:0015556	C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.3	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.3	GO:0016251	obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0	0.0	GO:0034618	arginine binding(GO:0034618)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0015645	fatty acid ligase activity(GO:0015645)
0.0	0.0	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.1	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0042288	MHC class I protein binding(GO:0042288)
0.0	0.1	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.0	0.5	GO:0050136	NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0010181	FMN binding(GO:0010181)
0.0	0.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	2.6	GO:0003924	GTPase activity(GO:0003924)
0.0	0.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.3	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.0	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.0	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	1.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.0	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.0	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.9	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.0	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.3	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.0	GO:0050542	icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0	0.0	GO:0015379	potassium:chloride symporter activity(GO:0015379)
0.0	0.0	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.0	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.2	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	0.7	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.0	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.0	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.0	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.0	0.1	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.1	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.1	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0009982	pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	0.1	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.5	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.3	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	1.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.6	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.6	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.0	0.5	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.1	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.6	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.5	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.8	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.2	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.5	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.6	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.8	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.0	0.5	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.0	0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.7	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.0	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.0	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.7	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.1	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	0.3	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.0	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID BARD1 PATHWAY	BARD1 signaling events
0.0	0.0	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.2	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.0	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.0	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.0	0.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.3	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.4	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	0.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.5	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1	1.7	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.1	0.5	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.6	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	1.0	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.2	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	0.6	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	1.1	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.2	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.5	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.4	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.4	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.4	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.0	0.1	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.1	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	0.4	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.6	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.2	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.6	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.9	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.0	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.0	0.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.3	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.0	0.1	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
0.0	0.6	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition
0.0	0.2	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.0	1.0	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0	0.1	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0	0.3	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	0.2	REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS	Genes involved in Amino acid and oligopeptide SLC transporters
0.0	0.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.2	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	0.2	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere

Results for KLF7

Z-value: 1.91

Motif logo

Transcription factors associated with KLF7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the KLF7 motif across conditions

Conditions sorted by the z-value of the KLF7 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF7

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: