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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for KLF7

Z-value: 1.91

Motif logo

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Transcription factors associated with KLF7

Gene Symbol Gene ID Gene Info
ENSG00000118263.10 KLF7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
KLF7chr2_208006684_20800683578980.200545-0.881.9e-03Click!
KLF7chr2_208000784_20800093519980.329023-0.781.3e-02Click!
KLF7chr2_208000481_20800074217500.362101-0.732.5e-02Click!
KLF7chr2_208017651_208017818125610.197360-0.694.1e-02Click!
KLF7chr2_208029828_208030644590.9789880.684.3e-02Click!

Activity of the KLF7 motif across conditions

Conditions sorted by the z-value of the KLF7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_111415846_111416285 0.99 CD53
CD53 molecule
289
0.91
chrX_129218649_129218800 0.98 ELF4
E74-like factor 4 (ets domain transcription factor)
25612
0.18
chr18_43268798_43268949 0.95 SLC14A2
solute carrier family 14 (urea transporter), member 2
22766
0.16
chr2_151412976_151413127 0.84 RND3
Rho family GTPase 3
17526
0.31
chr6_47666951_47667231 0.82 GPR115
G protein-coupled receptor 115
802
0.64
chr8_1431231_1431382 0.77 DLGAP2
discs, large (Drosophila) homolog-associated protein 2
18226
0.28
chr17_7210033_7210519 0.75 EIF5A
eukaryotic translation initiation factor 5A
42
0.92
chr19_55765720_55766271 0.73 PPP6R1
protein phosphatase 6, regulatory subunit 1
1142
0.27
chr11_20178638_20179031 0.73 DBX1
developing brain homeobox 1
3036
0.31
chr11_73490222_73490495 0.73 MRPL48
mitochondrial ribosomal protein L48
8003
0.15
chr2_110970201_110970394 0.73 NPHP1
nephronophthisis 1 (juvenile)
7654
0.23
chr6_116600126_116600342 0.70 TSPYL1
TSPY-like 1
832
0.44
chr3_47050667_47050875 0.69 NBEAL2
neurobeachin-like 2
4000
0.22
chr14_105331028_105331307 0.69 CEP170B
centrosomal protein 170B
450
0.81
chr1_9713633_9713784 0.67 C1orf200
chromosome 1 open reading frame 200
936
0.49
chr15_66649119_66649300 0.66 TIPIN
TIMELESS interacting protein
155
0.92
chr2_74165845_74165996 0.65 DGUOK
deoxyguanosine kinase
11885
0.15
chr19_48111330_48111585 0.65 GLTSCR1
glioma tumor suppressor candidate region gene 1
4
0.97
chr12_113770815_113771205 0.65 SLC8B1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
258
0.91
chr17_37558067_37558428 0.64 CTB-131K11.1

201
0.65
chrX_92928498_92928999 0.63 NAP1L3
nucleosome assembly protein 1-like 3
181
0.61
chr14_50985374_50985525 0.63 MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
13741
0.17
chr5_156968041_156968238 0.62 AC106801.1

24833
0.14
chr3_33138761_33138999 0.62 GLB1
galactosidase, beta 1
158
0.84
chr6_45983691_45983842 0.62 CLIC5
chloride intracellular channel 5
180
0.95
chr4_83350861_83351264 0.61 HNRNPDL
heterogeneous nuclear ribonucleoprotein D-like
43
0.93
chr1_89989972_89990271 0.61 LRRC8B
leucine rich repeat containing 8 family, member B
274
0.94
chr2_16081463_16081614 0.60 MYCNOS
MYCN opposite strand
166
0.89
chr13_74339708_74339938 0.60 KLF12
Kruppel-like factor 12
229363
0.02
chr6_36164322_36164500 0.58 BRPF3
bromodomain and PHD finger containing, 3
110
0.88
chr9_132653009_132653160 0.58 FNBP1
formin binding protein 1
28505
0.14
chr8_79577906_79578162 0.57 ZC2HC1A
zinc finger, C2HC-type containing 1A
248
0.95
chr2_201577972_201578363 0.57 AOX1
aldehyde oxidase 1
50537
0.11
chr7_157072586_157072755 0.57 ENSG00000266453
.
25817
0.21
chr13_76334632_76334929 0.57 LMO7
LIM domain 7
15
0.99
chr6_25042448_25042685 0.56 FAM65B
family with sequence similarity 65, member B
328
0.63
chr1_26872331_26872899 0.56 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
272
0.88
chr10_105880540_105880741 0.56 SFR1
SWI5-dependent recombination repair 1
1176
0.46
chr16_69516663_69516814 0.56 CYB5B
cytochrome b5 type B (outer mitochondrial membrane)
58052
0.09
chr1_154315658_154315860 0.55 ENSG00000238365
.
4540
0.12
chr3_197476356_197476565 0.55 FYTTD1
forty-two-three domain containing 1
36
0.58
chr9_95727201_95727619 0.55 FGD3
FYVE, RhoGEF and PH domain containing 3
1167
0.54
chr16_22384493_22384879 0.55 CDR2
cerebellar degeneration-related protein 2, 62kDa
1252
0.31
chr11_112833488_112833639 0.54 RP11-629G13.1

619
0.65
chr11_65029483_65029818 0.54 POLA2
polymerase (DNA directed), alpha 2, accessory subunit
217
0.91
chr7_104584495_104584838 0.54 ENSG00000251911
.
27068
0.16
chr14_75990098_75990249 0.53 BATF
basic leucine zipper transcription factor, ATF-like
1270
0.47
chr12_62656333_62656484 0.53 USP15
ubiquitin specific peptidase 15
2199
0.3
chr17_33673306_33673493 0.53 SLFN11
schlafen family member 11
6751
0.2
chr12_53773389_53773606 0.52 SP1
Sp1 transcription factor
463
0.73
chr1_109757024_109757692 0.52 SARS
seryl-tRNA synthetase
754
0.58
chr3_57677289_57677722 0.52 DENND6A
DENN/MADD domain containing 6A
1311
0.4
chr21_42741228_42741619 0.51 MX2
myxovirus (influenza virus) resistance 2 (mouse)
589
0.77
chr9_73026582_73027022 0.51 KLF9
Kruppel-like factor 9
2738
0.37
chr2_96657272_96657655 0.51 ANKRD36C
ankyrin repeat domain 36C
78
0.97
chr12_113494960_113495179 0.51 DTX1
deltex homolog 1 (Drosophila)
426
0.82
chr2_85153190_85153512 0.51 TMSB10
thymosin beta 10
20602
0.17
chr3_111260963_111261300 0.51 CD96
CD96 molecule
134
0.97
chr8_8203302_8203453 0.51 SGK223
Tyrosine-protein kinase SgK223
35880
0.18
chr12_133083604_133083856 0.50 FBRSL1
fibrosin-like 1
16573
0.19
chr3_9690857_9691008 0.50 MTMR14
myotubularin related protein 14
185
0.94
chr16_86638626_86639076 0.49 FOXL1
forkhead box L1
26736
0.16
chr11_73692681_73692970 0.49 UCP2
uncoupling protein 2 (mitochondrial, proton carrier)
842
0.53
chr10_134716551_134716702 0.49 TTC40
tetratricopeptide repeat domain 40
39463
0.18
chr6_89790098_89790249 0.49 RP11-63L7.5

213
0.59
chr6_36973743_36974036 0.49 FGD2
FYVE, RhoGEF and PH domain containing 2
466
0.8
chr2_46524572_46524838 0.49 EPAS1
endothelial PAS domain protein 1
164
0.97
chr1_249131820_249131984 0.49 ZNF672
zinc finger protein 672
577
0.67
chr4_185182739_185182890 0.48 ENSG00000221523
.
5770
0.22
chr5_67510861_67511301 0.48 PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
467
0.86
chr2_207115371_207115541 0.48 ENSG00000252716
.
9482
0.15
chr8_133787726_133787926 0.47 PHF20L1
PHD finger protein 20-like 1
0
0.98
chr13_101169809_101169960 0.47 PCCA
propionyl CoA carboxylase, alpha polypeptide
2203
0.29
chr14_103010712_103010863 0.47 ENSG00000266015
.
4806
0.19
chr5_159846201_159846839 0.47 SLU7
SLU7 splicing factor homolog (S. cerevisiae)
119
0.95
chr15_65282464_65282690 0.47 SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
71
0.97
chr6_4136387_4136965 0.47 ECI2
enoyl-CoA delta isomerase 2
845
0.44
chr9_139433085_139433378 0.46 RP11-413M3.4

4102
0.11
chr12_14518654_14518864 0.46 ATF7IP
activating transcription factor 7 interacting protein
96
0.98
chr9_33001711_33002097 0.46 APTX
aprataxin
265
0.91
chr3_150479775_150480371 0.46 SIAH2-AS1
SIAH2 antisense RNA 1
349
0.79
chr15_81426280_81426524 0.46 C15orf26
chromosome 15 open reading frame 26
186
0.96
chr5_36876188_36876410 0.46 NIPBL
Nipped-B homolog (Drosophila)
562
0.86
chr10_8068775_8069028 0.46 GATA3
GATA binding protein 3
27755
0.26
chr11_62308687_62309106 0.46 RP11-864I4.3

4112
0.1
chr11_62647941_62648236 0.45 SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
194
0.87
chr22_38793180_38793744 0.45 CSNK1E
casein kinase 1, epsilon
1065
0.4
chr18_33530285_33530492 0.45 ENSG00000265641
.
16283
0.17
chr5_90576543_90576733 0.44 ENSG00000199643
.
10094
0.28
chr2_74710229_74710420 0.44 CCDC142
coiled-coil domain containing 142
37
0.56
chr9_130733348_130733499 0.44 FAM102A
family with sequence similarity 102, member A
9369
0.11
chr19_15580698_15580960 0.43 RASAL3
RAS protein activator like 3
5447
0.13
chr12_52463075_52463333 0.43 C12orf44
chromosome 12 open reading frame 44
551
0.63
chr6_33239851_33240264 0.43 RPS18
ribosomal protein S18
205
0.61
chr22_31031104_31031465 0.43 SLC35E4
solute carrier family 35, member E4
355
0.81
chr2_70314282_70314484 0.43 PCBP1-AS1
PCBP1 antisense RNA 1
53
0.7
chr12_31226828_31227064 0.43 DDX11
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
114
0.57
chr12_120428180_120428604 0.43 CCDC64
coiled-coil domain containing 64
719
0.72
chr19_6590606_6591184 0.43 CD70
CD70 molecule
255
0.89
chr17_3289151_3289302 0.43 RP11-64J4.2

361
0.82
chr4_2801611_2801762 0.43 SH3BP2
SH3-domain binding protein 2
961
0.59
chr1_26646074_26646278 0.42 UBXN11
UBX domain protein 11
1322
0.27
chr17_76109268_76109419 0.42 ENSG00000204282
.
1463
0.29
chr7_27200041_27200697 0.42 HOXA7
homeobox A7
2814
0.08
chr16_79630640_79632238 0.42 MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
2360
0.43
chr6_35267446_35267597 0.41 DEF6
differentially expressed in FDCP 6 homolog (mouse)
1892
0.32
chr6_33539685_33539836 0.41 BAK1
BCL2-antagonist/killer 1
8221
0.13
chr3_32442741_32443149 0.41 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
9414
0.25
chr11_726415_726634 0.41 AP006621.9

523
0.57
chr15_50004365_50004516 0.41 RP11-353B9.1

60104
0.12
chr13_22178024_22178253 0.41 MICU2
mitochondrial calcium uptake 2
182
0.96
chr19_17590091_17590333 0.40 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
8914
0.08
chr19_46172257_46172467 0.40 GIPR
gastric inhibitory polypeptide receptor
847
0.37
chr1_205819043_205819299 0.40 PM20D1
peptidase M20 domain containing 1
74
0.97
chr19_51522437_51522588 0.40 KLK10
kallikrein-related peptidase 10
508
0.54
chrX_45709671_45710004 0.40 ENSG00000212347
.
42577
0.19
chr19_17622094_17622308 0.40 PGLS
6-phosphogluconolactonase
237
0.85
chr15_75199296_75199599 0.40 FAM219B
family with sequence similarity 219, member B
15
0.96
chr17_8089749_8090065 0.40 ENSG00000266638
.
586
0.5
chr15_41047576_41047750 0.39 RMDN3
regulator of microtubule dynamics 3
129
0.93
chr10_102588726_102589022 0.39 ENSG00000222072
.
78163
0.07
chr19_2775817_2776209 0.39 SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
5234
0.12
chr4_56719874_56720283 0.39 EXOC1
exocyst complex component 1
173
0.95
chr10_124135009_124135427 0.39 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
868
0.6
chr2_74881058_74881259 0.39 SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
197
0.93
chr6_116597784_116598857 0.39 TSPYL1
TSPY-like 1
2746
0.21
chr10_111986414_111986565 0.39 MXI1
MAX interactor 1, dimerization protein
647
0.75
chr10_12110997_12111197 0.39 DHTKD1
dehydrogenase E1 and transketolase domain containing 1
74
0.97
chr12_9436279_9436529 0.39 ENSG00000212440
.
3014
0.25
chr11_117860694_117860845 0.38 IL10RA
interleukin 10 receptor, alpha
3660
0.23
chr1_49242712_49243015 0.38 BEND5
BEN domain containing 5
273
0.95
chr10_97667704_97667951 0.38 C10orf131
chromosome 10 open reading frame 131
105
0.62
chr11_72853974_72854211 0.38 FCHSD2
FCH and double SH3 domains 2
786
0.69
chr1_26231368_26231927 0.38 STMN1
stathmin 1
28
0.94
chr17_13241369_13241749 0.38 ENSG00000266115
.
162086
0.04
chr1_173793809_173794356 0.38 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
285
0.7
chr1_154927193_154927621 0.38 PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
1173
0.25
chr8_8746534_8747046 0.37 MFHAS1
malignant fibrous histiocytoma amplified sequence 1
4365
0.23
chr19_49403923_49404430 0.37 NUCB1
nucleobindin 1
121
0.9
chr14_100704060_100704316 0.37 YY1
YY1 transcription factor
447
0.56
chr5_72251288_72251681 0.37 FCHO2
FCH domain only 2
324
0.92
chrX_154285608_154285801 0.37 CMC4
C-x(9)-C motif containing 4
7939
0.14
chr1_26561482_26561883 0.37 CEP85
centrosomal protein 85kDa
989
0.41
chrX_80457617_80458353 0.37 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
543
0.46
chr8_23075544_23076103 0.37 ENSG00000246582
.
6161
0.12
chr17_33814121_33814953 0.36 SLFN12L
schlafen family member 12-like
316
0.84
chr7_150373814_150373965 0.36 GIMAP2
GTPase, IMAP family member 2
8899
0.17
chr3_56591241_56591766 0.36 CCDC66
coiled-coil domain containing 66
287
0.94
chr12_4381277_4381428 0.36 CCND2
cyclin D2
1586
0.32
chr10_43133374_43133621 0.36 ZNF33B
zinc finger protein 33B
495
0.85
chr9_130736775_130737070 0.36 FAM102A
family with sequence similarity 102, member A
5870
0.12
chr8_128806891_128807842 0.36 ENSG00000249859
.
842
0.72
chr14_64107873_64108536 0.36 WDR89
WD repeat domain 89
79
0.96
chr6_144385545_144385940 0.36 PLAGL1
pleiomorphic adenoma gene-like 1
7
0.98
chr6_26597613_26597959 0.36 ABT1
activator of basal transcription 1
606
0.73
chr7_150070289_150070440 0.36 RP4-584D14.5

685
0.5
chrX_129245186_129245676 0.35 ELF4
E74-like factor 4 (ets domain transcription factor)
740
0.69
chr20_44486283_44486492 0.35 ZSWIM3
zinc finger, SWIM-type containing 3
131
0.72
chr5_99228364_99228515 0.35 ENSG00000199378
.
129069
0.06
chr17_4709881_4710063 0.35 PLD2
phospholipase D2
419
0.67
chr4_24584331_24584482 0.35 DHX15
DEAH (Asp-Glu-Ala-His) box helicase 15
1767
0.4
chr5_74348140_74348479 0.35 GCNT4
glucosaminyl (N-acetyl) transferase 4, core 2
21585
0.25
chr14_57046740_57047215 0.35 TMEM260
transmembrane protein 260
375
0.91
chr13_53226532_53226731 0.35 SUGT1
SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)
343
0.9
chr14_21131236_21131389 0.35 ENSG00000199461
.
16258
0.09
chr8_9008533_9008971 0.35 PPP1R3B
protein phosphatase 1, regulatory subunit 3B
332
0.62
chr1_147807090_147807347 0.35 ENSG00000202408
.
332
0.85
chrX_149860911_149861411 0.35 MTMR1
myotubularin related protein 1
274
0.95
chr16_9184823_9185042 0.35 C16orf72
chromosome 16 open reading frame 72
573
0.72
chr6_137540064_137540505 0.34 IFNGR1
interferon gamma receptor 1
215
0.96
chr22_32366297_32366691 0.34 ENSG00000240647
.
10920
0.14
chr16_11438920_11439177 0.34 RP11-485G7.5

6
0.75
chr22_38349726_38350087 0.34 POLR2F
polymerase (RNA) II (DNA directed) polypeptide F
172
0.56
chr17_46115604_46115869 0.34 COPZ2
coatomer protein complex, subunit zeta 2
344
0.7
chr17_72734396_72734547 0.34 RAB37
RAB37, member RAS oncogene family
1100
0.33
chr12_104851638_104851843 0.34 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
961
0.68
chr19_46171751_46172236 0.34 GIPR
gastric inhibitory polypeptide receptor
478
0.61
chr4_109087549_109087740 0.34 LEF1
lymphoid enhancer-binding factor 1
187
0.91
chr20_31330734_31331002 0.34 COMMD7
COMM domain containing 7
344
0.88
chr9_276345_276496 0.34 DOCK8
dedicator of cytokinesis 8
3350
0.24
chr22_43411396_43411716 0.34 PACSIN2
protein kinase C and casein kinase substrate in neurons 2
405
0.85
chr20_32262337_32262536 0.34 RP1-63M2.5

113
0.56
chr17_45811310_45811575 0.34 TBX21
T-box 21
832
0.55
chr17_21454142_21454502 0.34 C17orf51
chromosome 17 open reading frame 51
621
0.75
chr5_54830989_54831249 0.34 PPAP2A
phosphatidic acid phosphatase type 2A
241
0.94
chr2_43037752_43038106 0.34 HAAO
3-hydroxyanthranilate 3,4-dioxygenase
18197
0.23
chr2_192176235_192176432 0.34 MYO1B
myosin IB
34722
0.2
chrX_130912849_130913434 0.34 ENSG00000200587
.
159843
0.04
chr7_99647395_99647894 0.34 ZSCAN21
zinc finger and SCAN domain containing 21
227
0.84
chr20_5731235_5731458 0.33 C20orf196
chromosome 20 open reading frame 196
247
0.95
chr16_2317361_2317547 0.33 RNPS1
RNA binding protein S1, serine-rich domain
116
0.77
chr16_72127792_72128009 0.33 DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
77
0.57
chr6_106546757_106547354 0.33 PRDM1
PR domain containing 1, with ZNF domain
240
0.87
chr17_37025636_37026147 0.33 LASP1
LIM and SH3 protein 1
221
0.86
chr1_12128033_12128184 0.33 TNFRSF8
tumor necrosis factor receptor superfamily, member 8
4581
0.16
chr22_39640196_39640514 0.33 PDGFB
platelet-derived growth factor beta polypeptide
401
0.8
chr15_67547384_67547573 0.33 AAGAB
alpha- and gamma-adaptin binding protein
55
0.81
chr19_7694674_7695267 0.33 PET100
PET100 homolog (S. cerevisiae)
260
0.65
chr20_61437961_61438112 0.33 OGFR
opioid growth factor receptor
589
0.53
chr19_45251774_45251925 0.33 BCL3
B-cell CLL/lymphoma 3
45
0.96

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of KLF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.2 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational elongation(GO:0045901) positive regulation of translational termination(GO:0045905)
0.2 0.7 GO:0002093 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.2 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.4 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.1 0.4 GO:0015801 aromatic amino acid transport(GO:0015801)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.4 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.2 GO:0090382 phagolysosome assembly(GO:0001845) phagosome maturation(GO:0090382)
0.1 0.3 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.1 0.3 GO:0051832 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.1 0.3 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.2 GO:0032928 regulation of superoxide anion generation(GO:0032928)
0.1 0.3 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.3 GO:0001743 optic placode formation(GO:0001743)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.1 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.2 GO:2000330 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.3 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.3 GO:0031427 response to methotrexate(GO:0031427)
0.1 0.2 GO:0016559 peroxisome fission(GO:0016559)
0.1 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.1 0.2 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065) UDP-glucuronate metabolic process(GO:0046398)
0.1 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.4 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.2 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.2 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.2 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 0.2 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 0.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661) regulation of mesoderm development(GO:2000380)
0.1 0.1 GO:0032055 negative regulation of translation in response to stress(GO:0032055)
0.1 0.4 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.2 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.1 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.3 GO:0002063 chondrocyte development(GO:0002063)
0.1 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.2 GO:0043320 natural killer cell activation involved in immune response(GO:0002323) natural killer cell degranulation(GO:0043320)
0.1 0.4 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin(GO:0001991)
0.1 0.2 GO:0021563 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.2 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 0.2 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.1 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.1 0.2 GO:0070669 response to interleukin-2(GO:0070669)
0.1 0.2 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.4 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.2 GO:0017085 response to insecticide(GO:0017085)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0010823 negative regulation of mitochondrion organization(GO:0010823) negative regulation of release of cytochrome c from mitochondria(GO:0090201) negative regulation of apoptotic signaling pathway(GO:2001234)
0.0 0.2 GO:0031943 regulation of glucocorticoid metabolic process(GO:0031943)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.2 GO:0043302 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of leukocyte degranulation(GO:0043302) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0030011 maintenance of cell polarity(GO:0030011)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0006390 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 0.2 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.2 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.2 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.3 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) COPII-coated vesicle budding(GO:0090114)
0.0 0.3 GO:0007063 regulation of sister chromatid cohesion(GO:0007063)
0.0 0.0 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.2 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus(GO:0071428)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0032350 regulation of hormone metabolic process(GO:0032350)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.2 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.1 GO:0048670 regulation of collateral sprouting(GO:0048670)
0.0 0.4 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.4 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.4 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 0.0 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.2 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.2 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.3 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.5 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0050685 positive regulation of mRNA 3'-end processing(GO:0031442) positive regulation of mRNA processing(GO:0050685) positive regulation of mRNA metabolic process(GO:1903313)
0.0 0.1 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.1 GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0072087 renal vesicle development(GO:0072087)
0.0 0.4 GO:0008593 regulation of Notch signaling pathway(GO:0008593)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.0 0.1 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.3 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:1903579 negative regulation of nucleoside metabolic process(GO:0045978) negative regulation of ATP metabolic process(GO:1903579)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.2 GO:0050718 positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 0.1 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.9 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate pattern specification(GO:0060896) neural plate regionalization(GO:0060897)
0.0 0.1 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) negative regulation of vitamin D biosynthetic process(GO:0010957) negative regulation of vitamin metabolic process(GO:0046137)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0 0.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.3 GO:0034620 endoplasmic reticulum unfolded protein response(GO:0030968) cellular response to unfolded protein(GO:0034620)
0.0 0.4 GO:0060330 regulation of response to interferon-gamma(GO:0060330) regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.3 GO:0001706 endoderm formation(GO:0001706)
0.0 0.7 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.2 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.0 GO:0051957 positive regulation of amino acid transport(GO:0051957)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.0 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.1 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0009158 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0046629 gamma-delta T cell activation(GO:0046629)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003)
0.0 0.1 GO:0031641 regulation of myelination(GO:0031641)
0.0 0.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0045909 positive regulation of vasodilation(GO:0045909)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0001782 B cell homeostasis(GO:0001782)
0.0 0.2 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.4 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.1 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.0 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.0 GO:0071168 protein localization to chromatin(GO:0071168)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.2 GO:0000303 response to superoxide(GO:0000303)
0.0 0.0 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.2 GO:0006896 Golgi to endosome transport(GO:0006895) Golgi to vacuole transport(GO:0006896)
0.0 0.1 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0097300 necroptotic process(GO:0070266) programmed necrotic cell death(GO:0097300)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.0 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.1 GO:0021938 smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.0 0.0 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity(GO:1901021) positive regulation of cation channel activity(GO:2001259)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507) heterochromatin organization(GO:0070828)
0.0 0.2 GO:0006596 polyamine biosynthetic process(GO:0006596)
0.0 0.2 GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401) adaptation of signaling pathway(GO:0023058)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0016236 macroautophagy(GO:0016236)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.0 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045) central nervous system vasculogenesis(GO:0022009)
0.0 0.1 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.1 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.1 GO:0051926 negative regulation of calcium ion transport(GO:0051926)
0.0 0.1 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.2 GO:0044550 secondary metabolite biosynthetic process(GO:0044550)
0.0 0.1 GO:0043247 telomere capping(GO:0016233) protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.0 GO:0000768 syncytium formation by plasma membrane fusion(GO:0000768)
0.0 0.1 GO:0030149 sphingolipid catabolic process(GO:0030149)
0.0 0.0 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.2 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.2 GO:0006386 transcription elongation from RNA polymerase III promoter(GO:0006385) termination of RNA polymerase III transcription(GO:0006386)
0.0 0.3 GO:0032006 regulation of TOR signaling(GO:0032006)
0.0 0.1 GO:0045749 obsolete negative regulation of S phase of mitotic cell cycle(GO:0045749)
0.0 0.5 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.1 GO:0042987 amyloid precursor protein catabolic process(GO:0042987)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.1 GO:0021591 ventricular system development(GO:0021591)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.0 GO:0031223 auditory behavior(GO:0031223)
0.0 0.1 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.4 GO:0009395 phospholipid catabolic process(GO:0009395)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.0 0.0 GO:0007144 female meiosis I(GO:0007144)
0.0 0.0 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.0 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.0 GO:0000731 DNA synthesis involved in DNA repair(GO:0000731)
0.0 0.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.0 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.0 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.2 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.0 0.1 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.0 GO:0046931 pore complex assembly(GO:0046931)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.0 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 1.0 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.0 GO:0060997 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:0031113 regulation of microtubule polymerization(GO:0031113)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.0 GO:0070234 positive regulation of lymphocyte apoptotic process(GO:0070230) positive regulation of T cell apoptotic process(GO:0070234) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.2 GO:0019674 NAD metabolic process(GO:0019674)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:0007031 peroxisome organization(GO:0007031)
0.0 0.0 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.0 GO:0021783 facial nerve development(GO:0021561) preganglionic parasympathetic fiber development(GO:0021783)
0.0 0.2 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.0 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.2 GO:0007632 visual behavior(GO:0007632)
0.0 0.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.0 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.1 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.0 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.0 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.0 GO:0052555 pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response(GO:0052033) positive regulation by symbiont of host innate immune response(GO:0052166) modulation by symbiont of host innate immune response(GO:0052167) pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response(GO:0052169) pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction(GO:0052257) positive regulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052305) modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052306) pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction(GO:0052308) positive regulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052555) positive regulation by symbiont of host immune response(GO:0052556)
0.0 0.1 GO:0019682 pentose-phosphate shunt(GO:0006098) glyceraldehyde-3-phosphate metabolic process(GO:0019682)
0.0 0.1 GO:0009086 methionine biosynthetic process(GO:0009086)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0045010 actin nucleation(GO:0045010)
0.0 0.3 GO:0007569 cell aging(GO:0007569)
0.0 1.3 GO:0006184 obsolete GTP catabolic process(GO:0006184)
0.0 0.1 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.2 GO:0048536 spleen development(GO:0048536)
0.0 0.3 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.1 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.0 0.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.0 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.1 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0051955 regulation of amino acid transport(GO:0051955)
0.0 0.1 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.5 GO:0006826 iron ion transport(GO:0006826)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.5 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.3 GO:0042587 glycogen granule(GO:0042587)
0.1 0.4 GO:0005678 obsolete chromatin assembly complex(GO:0005678)
0.1 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 0.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.5 GO:0000145 exocyst(GO:0000145)
0.1 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.7 GO:0000299 obsolete integral to membrane of membrane fraction(GO:0000299)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070062 extracellular exosome(GO:0070062) extracellular vesicle(GO:1903561)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.0 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0042827 platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.0 2.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.3 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.2 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.1 GO:0030894 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 0.3 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.9 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.0 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.9 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.5 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 1.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0000407 pre-autophagosomal structure(GO:0000407) pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 2.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0032449 CBM complex(GO:0032449)
0.0 0.0 GO:0045277 mitochondrial respiratory chain complex IV(GO:0005751) respiratory chain complex IV(GO:0045277)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.9 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:1902555 endoribonuclease complex(GO:1902555)
0.0 0.1 GO:0008278 cohesin complex(GO:0008278)
0.0 0.0 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.0 GO:0033185 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.1 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.6 GO:0015925 galactosidase activity(GO:0015925)
0.1 0.4 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.6 GO:0004904 interferon receptor activity(GO:0004904)
0.1 0.3 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.3 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.1 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 0.3 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.5 GO:0034452 dynactin binding(GO:0034452)
0.1 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.3 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.4 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.3 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.3 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.1 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.1 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.2 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.6 GO:0052866 phosphatidylinositol phosphate phosphatase activity(GO:0052866)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0031177 phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0061659 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0055103 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.3 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity(GO:0016847)
0.0 0.0 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity(GO:0004607)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0090079 translation regulator activity, nucleic acid binding(GO:0090079)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.0 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.4 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0017069 snRNA binding(GO:0017069)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.2 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.0 GO:0070215 obsolete MDM2 binding(GO:0070215)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.4 GO:0043499 obsolete eukaryotic cell surface binding(GO:0043499)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.1 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.6 GO:0002020 protease binding(GO:0002020)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.1 GO:0046979 TAP binding(GO:0046977) TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.5 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.2 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.0 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.0 GO:0016362 activin receptor activity, type II(GO:0016362)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.1 GO:0015556 C4-dicarboxylate transmembrane transporter activity(GO:0015556)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.3 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0016251 obsolete general RNA polymerase II transcription factor activity(GO:0016251)
0.0 0.0 GO:0034618 arginine binding(GO:0034618)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 0.0 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0050136 NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0010181 FMN binding(GO:0010181)
0.0 0.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.6 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.3 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.0 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.9 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.0 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.0 GO:0050542 icosanoid binding(GO:0050542) fatty acid derivative binding(GO:1901567)
0.0 0.0 GO:0015379 potassium:chloride symporter activity(GO:0015379)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.0 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.9 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 0.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.5 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.0 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 PID P73PATHWAY p73 transcription factor network
0.0 0.3 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.1 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.0 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.0 0.6 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.0 0.1 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.1 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere