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ENCODE: H3K4me3 ChIP-Seq of primary human cells
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Results for LHX2

Z-value: 2.18

Motif logo

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Transcription factors associated with LHX2

Gene Symbol Gene ID Gene Info
LHX2
ENSG00000106689.6 LIM homeobox 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr9_126759855_126760197LHX239230.195546-0.637.0e-02Click!
chr9_126773746_126773955LHX2390.947237-0.511.6e-01Click!
chr9_126774768_126775305LHX24000.790921-0.472.1e-01Click!
chr9_126781132_126781283LHX235310.195483-0.452.2e-01Click!
chr9_126777225_126777376LHX23760.829399-0.353.6e-01Click!

Activity of the LHX2 motif across conditions

Conditions sorted by the z-value of the LHX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_148829582_148830289 0.82 ENSG00000223322
 .
 15441
 0.29
chr7_93550787_93551002 0.71 GNG11
 guanine nucleotide binding protein (G protein), gamma 11
 117
 0.96
chr4_54063057_54063462 0.69 ENSG00000207385
 .
 68475
 0.13
chr14_45433796_45433989 0.68 FAM179B
 family with sequence similarity 179, member B
 2450
 0.23
chr15_48935948_48936126 0.67 FBN1
 fibrillin 1
 1881
 0.46
chr4_114898942_114899097 0.64 ARSJ
 arylsulfatase family, member J
 1133
 0.61
chr11_132863892_132864419 0.62 OPCML
 opioid binding protein/cell adhesion molecule-like
 50492
 0.18
chr8_89338531_89338740 0.61 RP11-586K2.1
430
 0.76
chr6_85470567_85470756 0.58 TBX18
 T-box 18
 2412
 0.42
chr10_128249841_128250268 0.58 ENSG00000221717
 .
 4421
 0.3
chr4_81191052_81191243 0.56 FGF5
 fibroblast growth factor 5
 3354
 0.31
chr13_103478539_103479046 0.56 ENSG00000222301
 .
 6449
 0.13
chr7_94025506_94025990 0.55 COL1A2
 collagen, type I, alpha 2
 1875
 0.46
chr22_45900582_45901194 0.55 FBLN1
 fibulin 1
 1962
 0.36
chr11_12529707_12530128 0.55 PARVA
 parvin, alpha
 55635
 0.15
chr4_4494063_4494282 0.54 STX18-IT1
 STX18 intronic transcript 1 (non-protein coding)
 10745
 0.21
chr2_175710742_175710893 0.54 CHN1
 chimerin 1
 316
 0.93
chr11_36252522_36252860 0.53 COMMD9
 COMM domain containing 9
 58283
 0.13
chr4_160170135_160170337 0.51 RAPGEF2
 Rap guanine nucleotide exchange factor (GEF) 2
 17797
 0.23
chr6_130392038_130392189 0.51 L3MBTL3
 l(3)mbt-like 3 (Drosophila)
 50411
 0.15
chr4_138449879_138450179 0.51 PCDH18
 protocadherin 18
 3536
 0.4
chr13_100225293_100225444 0.50 CLYBL
 citrate lyase beta like
 33551
 0.14
chr4_99578140_99578845 0.50 TSPAN5
 tetraspanin 5
 294
 0.89
chr2_229517064_229517215 0.50 ENSG00000251801
 .
 64550
 0.15
chr2_227049788_227050011 0.50 ENSG00000263363
 .
 473610
 0.01
chr3_115961041_115961192 0.50 LSAMP-AS1
 LSAMP antisense RNA 1
 117755
 0.07
chr12_59310321_59310512 0.49 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 2052
 0.37
chr22_36235496_36235773 0.48 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
 631
 0.82
chr7_16709331_16709660 0.48 BZW2
 basic leucine zipper and W2 domains 2
 7737
 0.2
chr15_96885905_96886056 0.47 ENSG00000222651
 .
 9490
 0.16
chr12_26147598_26147778 0.47 RASSF8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 249
 0.94
chr8_93082068_93082219 0.47 RUNX1T1
 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
 1472
 0.57
chr12_43741404_43741555 0.46 ENSG00000215993
 .
 56096
 0.16
chr15_42749459_42749764 0.46 ZNF106
 zinc finger protein 106
 100
 0.96
chr17_13503089_13503240 0.46 HS3ST3A1
 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
 2080
 0.42
chr5_95068559_95068710 0.46 CTD-2154I11.2
635
 0.64
chr4_121990444_121990801 0.46 NDNF
 neuron-derived neurotrophic factor
 2534
 0.31
chr4_86790910_86791061 0.45 ENSG00000265774
 .
 40711
 0.17
chr4_77611462_77611724 0.45 AC107072.2
52817
 0.12
chr12_59312115_59312531 0.45 LRIG3
 leucine-rich repeats and immunoglobulin-like domains 3
 1004
 0.56
chr2_33822690_33822841 0.45 FAM98A
 family with sequence similarity 98, member A
 1579
 0.47
chr19_13137194_13137536 0.44 NFIX
 nuclear factor I/X (CCAAT-binding transcription factor)
 1554
 0.23
chr1_117636227_117636430 0.44 ENSG00000215930
 .
 937
 0.49
chr18_74409526_74409726 0.44 ENSG00000252097
 .
 103104
 0.07
chr1_196621837_196622284 0.43 CFH
 complement factor H
 874
 0.67
chr2_219435462_219435613 0.43 RQCD1
 RCD1 required for cell differentiation1 homolog (S. pombe)
 1939
 0.2
chr6_86159887_86160764 0.43 NT5E
 5'-nucleotidase, ecto (CD73)
 498
 0.87
chr13_33779104_33779430 0.42 STARD13
 StAR-related lipid transfer (START) domain containing 13
 876
 0.67
chr8_116675050_116675578 0.42 TRPS1
 trichorhinophalangeal syndrome I
 1409
 0.6
chr14_101294075_101294314 0.42 AL117190.2
1343
 0.15
chr11_91714959_91715138 0.42 FAT3
 FAT atypical cadherin 3
 370214
 0.01
chr3_157157796_157157947 0.41 PTX3
 pentraxin 3, long
 3293
 0.33
chr17_76036766_76037651 0.41 TNRC6C
 trinucleotide repeat containing 6C
 80
 0.97
chr1_201509442_201509672 0.41 CSRP1
 cysteine and glycine-rich protein 1
 30973
 0.13
chr10_69832583_69833003 0.41 HERC4
 HECT and RLD domain containing E3 ubiquitin protein ligase 4
 1101
 0.53
chr1_119521934_119522435 0.41 TBX15
 T-box 15
 8244
 0.28
chr10_90041933_90042089 0.41 ENSG00000200891
 .
 287559
 0.01
chrX_34671991_34672311 0.40 TMEM47
 transmembrane protein 47
 3254
 0.41
chr7_15723235_15723386 0.40 MEOX2
 mesenchyme homeobox 2
 3127
 0.32
chr11_122050333_122050506 0.40 ENSG00000207994
 .
 27403
 0.16
chrX_115371447_115371702 0.40 AGTR2
 angiotensin II receptor, type 2
 69599
 0.13
chr22_29489752_29489903 0.40 CTA-747E2.10
17844
 0.13
chr1_179111271_179111703 0.40 ABL2
 c-abl oncogene 2, non-receptor tyrosine kinase
 692
 0.72
chr12_20525245_20525493 0.39 RP11-284H19.1
2173
 0.35
chr15_81073340_81073491 0.39 KIAA1199
 KIAA1199
 1703
 0.42
chr5_172753672_172753903 0.39 STC2
 stanniocalcin 2
 13
 0.98
chr13_24778161_24778312 0.39 ENSG00000252695
 .
 41681
 0.13
chr16_69478979_69479169 0.39 CYB5B
 cytochrome b5 type B (outer mitochondrial membrane)
 20388
 0.15
chr10_728995_729174 0.39 DIP2C
 DIP2 disco-interacting protein 2 homolog C (Drosophila)
 6522
 0.18
chr21_32715523_32716836 0.39 TIAM1
 T-cell lymphoma invasion and metastasis 1
 415
 0.91
chr10_70321971_70322188 0.39 TET1
 tet methylcytosine dioxygenase 1
 1666
 0.36
chr1_70818696_70818847 0.39 ANKRD13C
 ankyrin repeat domain 13C
 1634
 0.29
chr12_18449684_18450065 0.39 PIK3C2G
 phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
 14896
 0.31
chr21_37312564_37312715 0.39 FKSG68
41912
 0.14
chr17_63549735_63549886 0.39 AXIN2
 axin 2
 5037
 0.32
chr3_79066759_79066910 0.39 ROBO1
 roundabout, axon guidance receptor, homolog 1 (Drosophila)
 860
 0.75
chr5_102209163_102209314 0.39 PAM
 peptidylglycine alpha-amidating monooxygenase
 7418
 0.33
chr12_91575190_91575391 0.39 DCN
 decorin
 537
 0.85
chr17_18090882_18091033 0.39 RP11-258F1.1
2890
 0.16
chr12_91576386_91576586 0.38 DCN
 decorin
 0
 0.99
chr1_247611615_247612128 0.38 OR2B11
 olfactory receptor, family 2, subfamily B, member 11
 3437
 0.2
chr11_19736431_19736825 0.38 NAV2
 neuron navigator 2
 1485
 0.49
chr3_157158697_157158863 0.38 PTX3
 pentraxin 3, long
 4202
 0.3
chr10_120031586_120031737 0.38 FAM204A
 family with sequence similarity 204, member A
 70091
 0.13
chr16_64450080_64450292 0.38 CDH11
 cadherin 11, type 2, OB-cadherin (osteoblast)
 643395
 0.0
chr16_59668238_59668389 0.38 ENSG00000200062
 .
 94283
 0.09
chr1_34629900_34630098 0.38 CSMD2
 CUB and Sushi multiple domains 2
 876
 0.55
chr10_33670460_33670611 0.38 NRP1
 neuropilin 1
 45345
 0.19
chr7_137028318_137028638 0.38 PTN
 pleiotrophin
 42
 0.99
chr10_30504590_30504756 0.37 ENSG00000200887
 .
 83929
 0.09
chr1_156087932_156088663 0.37 LMNA
 lamin A/C
 3784
 0.13
chr11_119292436_119293234 0.37 THY1
 Thy-1 cell surface antigen
 437
 0.74
chr4_122077287_122077641 0.37 TNIP3
 TNFAIP3 interacting protein 3
 8031
 0.23
chr13_45146263_45146555 0.37 TSC22D1
 TSC22 domain family, member 1
 3983
 0.32
chr9_98335013_98335164 0.37 PTCH1
 patched 1
 55749
 0.12
chr10_33622034_33622426 0.37 NRP1
 neuropilin 1
 1080
 0.63
chr2_238322401_238322657 0.37 COL6A3
 collagen, type VI, alpha 3
 262
 0.93
chr8_24366535_24366686 0.37 RP11-561E1.1
5491
 0.24
chr18_32075591_32075742 0.36 DTNA
 dystrobrevin, alpha
 1799
 0.52
chr13_91965562_91965713 0.36 ENSG00000215417
 .
 37222
 0.22
chr3_134091064_134091340 0.36 AMOTL2
 angiomotin like 2
 448
 0.85
chr6_148831295_148831530 0.36 ENSG00000223322
 .
 13964
 0.3
chr3_29566924_29567075 0.36 RBMS3-AS2
 RBMS3 antisense RNA 2
 91547
 0.09
chr6_128841955_128842296 0.36 PTPRK
 protein tyrosine phosphatase, receptor type, K
 255
 0.91
chr2_40591154_40591305 0.36 SLC8A1
 solute carrier family 8 (sodium/calcium exchanger), member 1
 66191
 0.13
chr2_227658547_227658788 0.36 IRS1
 insulin receptor substrate 1
 5808
 0.22
chr15_57509304_57509455 0.36 TCF12
 transcription factor 12
 2249
 0.41
chr21_17497567_17497931 0.36 ENSG00000252273
 .
 89920
 0.1
chr15_37395216_37395447 0.35 MEIS2
 Meis homeobox 2
 1827
 0.38
chr1_54232654_54232848 0.35 ENSG00000201003
 .
 4075
 0.22
chr6_18749403_18749554 0.35 ENSG00000207775
 .
 177463
 0.03
chr1_162791853_162792918 0.35 HSD17B7
 hydroxysteroid (17-beta) dehydrogenase 7
 31806
 0.15
chr5_71543858_71544009 0.35 ENSG00000244748
 .
 66582
 0.09
chr18_10059803_10059983 0.35 ENSG00000263630
 .
 54699
 0.15
chr7_94026391_94026542 0.35 COL1A2
 collagen, type I, alpha 2
 2593
 0.39
chr14_52122431_52122582 0.35 FRMD6
 FERM domain containing 6
 3808
 0.24
chr11_108766543_108766821 0.35 ENSG00000201243
 .
 109562
 0.07
chr9_17005379_17005546 0.35 ENSG00000241152
 .
 48437
 0.18
chr9_99277013_99277426 0.35 CDC14B
 cell division cycle 14B
 51893
 0.13
chr3_29327656_29328192 0.35 RBMS3-AS3
 RBMS3 antisense RNA 3
 4293
 0.26
chr6_127836184_127836541 0.35 SOGA3
 SOGA family member 3
 1397
 0.51
chr7_120726405_120726556 0.34 ENSG00000212628
 .
 2613
 0.31
chr18_53070200_53070424 0.34 TCF4
 transcription factor 4
 625
 0.79
chr7_83822532_83822694 0.34 SEMA3A
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
 1604
 0.57
chr12_54672073_54672366 0.34 CBX5
 chromobox homolog 5
 1667
 0.15
chr1_223895189_223895645 0.34 CAPN2
 calpain 2, (m/II) large subunit
 4617
 0.23
chr6_132269338_132269679 0.34 RP11-69I8.3
2578
 0.29
chr11_89938699_89938850 0.34 CHORDC1
 cysteine and histidine-rich domain (CHORD) containing 1
 3872
 0.31
chr5_158426214_158426386 0.34 CTD-2363C16.2
13486
 0.22
chr4_38011358_38011509 0.34 TBC1D1
 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
 17976
 0.25
chr18_32291325_32291476 0.34 DTNA
 dystrobrevin, alpha
 1139
 0.62
chr14_67878511_67879217 0.34 PLEK2
 pleckstrin 2
 53
 0.97
chr4_159041557_159041708 0.34 FAM198B
 family with sequence similarity 198, member B
 39201
 0.16
chr17_48295929_48296104 0.34 COL1A1
 collagen, type I, alpha 1
 17023
 0.11
chr11_124513856_124514050 0.33 ENSG00000200278
 .
 7598
 0.12
chr5_15510117_15510353 0.33 FBXL7
 F-box and leucine-rich repeat protein 7
 8688
 0.31
chr15_48936207_48936433 0.33 FBN1
 fibrillin 1
 1598
 0.51
chr9_16869648_16869822 0.33 BNC2
 basonuclin 2
 969
 0.71
chr7_95704908_95705546 0.33 ENSG00000208025
 .
 143841
 0.04
chr8_122650853_122651057 0.33 HAS2-AS1
 HAS2 antisense RNA 1
 578
 0.78
chr6_57035944_57036095 0.33 RP11-203B9.4
172
 0.92
chr13_33896904_33897055 0.33 ENSG00000264288
 .
 14130
 0.21
chr11_94527493_94527644 0.33 AMOTL1
 angiomotin like 1
 26031
 0.2
chr1_215130950_215131319 0.33 KCNK2
 potassium channel, subfamily K, member 2
 48064
 0.2
chr7_28312230_28312417 0.33 CREB5
 cAMP responsive element binding protein 5
 26617
 0.2
chr10_95813368_95813519 0.33 ENSG00000252895
 .
 6561
 0.2
chr8_67522944_67523356 0.33 MYBL1
 v-myb avian myeloblastosis viral oncogene homolog-like 1
 1992
 0.31
chr20_4953796_4953984 0.32 SLC23A2
 solute carrier family 23 (ascorbic acid transporter), member 2
 28255
 0.16
chr2_104572278_104572429 0.32 ENSG00000199727
 .
 576878
 0.0
chr14_45711437_45711895 0.32 MIS18BP1
 MIS18 binding protein 1
 10714
 0.2
chr12_78078846_78079000 0.32 AC073528.1
128355
 0.06
chr2_200446222_200446758 0.32 SATB2
 SATB homeobox 2
 110501
 0.07
chr11_23919257_23919465 0.32 ENSG00000252519
 .
 48037
 0.2
chr6_159360525_159360963 0.32 ENSG00000223191
 .
 13141
 0.19
chr16_89990965_89991193 0.32 TUBB3
 Tubulin beta-3 chain
 1305
 0.26
chr20_42667406_42667585 0.32 TOX2
 TOX high mobility group box family member 2
 15496
 0.21
chr3_87036535_87037613 0.32 VGLL3
 vestigial like 3 (Drosophila)
 2778
 0.42
chr12_21926599_21927146 0.32 KCNJ8
 potassium inwardly-rectifying channel, subfamily J, member 8
 883
 0.57
chr5_16713364_16713515 0.32 MYO10
 myosin X
 25057
 0.21
chr1_42383823_42384248 0.31 HIVEP3
 human immunodeficiency virus type I enhancer binding protein 3
 134
 0.98
chr1_215181172_215181323 0.31 KCNK2
 potassium channel, subfamily K, member 2
 2049
 0.5
chr7_92327766_92328157 0.31 ENSG00000206763
 .
 3167
 0.33
chr10_7914212_7914417 0.31 TAF3
 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
 53847
 0.14
chr1_224805331_224805508 0.31 CNIH3
 cornichon family AMPA receptor auxiliary protein 3
 1424
 0.35
chr7_121078096_121078495 0.31 FAM3C
 family with sequence similarity 3, member C
 41877
 0.19
chr16_15588070_15588221 0.31 C16orf45
 chromosome 16 open reading frame 45
 7978
 0.23
chr1_48174846_48175814 0.31 FLJ00388
51960
 0.16
chr2_230138192_230138530 0.31 PID1
 phosphotyrosine interaction domain containing 1
 2360
 0.4
chr6_148664293_148664728 0.31 SASH1
 SAM and SH3 domain containing 1
 781
 0.74
chr9_118915780_118915931 0.31 PAPPA
 pregnancy-associated plasma protein A, pappalysin 1
 228
 0.95
chr15_99297407_99297593 0.31 ENSG00000264480
 .
 30155
 0.19
chr8_40011594_40011745 0.31 C8orf4
 chromosome 8 open reading frame 4
 680
 0.81
chr14_30696659_30696810 0.31 PRKD1
 protein kinase D1
 35630
 0.23
chr12_127568278_127568473 0.31 ENSG00000239776
 .
 82297
 0.12
chr6_152701966_152702349 0.31 SYNE1-AS1
 SYNE1 antisense RNA 1
 476
 0.79
chr2_161767569_161767862 0.31 ENSG00000244372
 .
 33657
 0.24
chr18_7617915_7618177 0.30 PTPRM
 protein tyrosine phosphatase, receptor type, M
 50229
 0.16
chr7_114055046_114055222 0.30 FOXP2
 forkhead box P2
 21
 0.98
chr4_20420225_20420376 0.30 SLIT2-IT1
 SLIT2 intronic transcript 1 (non-protein coding)
 26488
 0.25
chr12_95868834_95869163 0.30 METAP2
 methionyl aminopeptidase 2
 1060
 0.55
chr13_36047277_36047487 0.30 MAB21L1
 mab-21-like 1 (C. elegans)
 3450
 0.24
chr10_95802235_95802386 0.30 ENSG00000252895
 .
 4572
 0.22
chr1_178602075_178602251 0.30 ENSG00000266417
 .
 44721
 0.13
chr12_2162213_2162837 0.30 CACNA1C
 calcium channel, voltage-dependent, L type, alpha 1C subunit
 61
 0.97
chr12_91487813_91488090 0.30 LUM
 lumican
 17657
 0.21
chr15_57978292_57978443 0.30 POLR2M
 polymerase (RNA) II (DNA directed) polypeptide M
 20460
 0.23
chr15_37176117_37176447 0.30 ENSG00000212511
 .
 31441
 0.23
chr8_121137253_121137925 0.30 COL14A1
 collagen, type XIV, alpha 1
 237
 0.96
chr9_112942337_112942488 0.30 C9orf152
 chromosome 9 open reading frame 152
 28057
 0.2
chr1_164534283_164534434 0.30 PBX1
 pre-B-cell leukemia homeobox 1
 2316
 0.4
chr1_100232300_100232564 0.30 FRRS1
 ferric-chelate reductase 1
 1083
 0.49
chr3_15369209_15369360 0.30 SH3BP5
 SH3-domain binding protein 5 (BTK-associated)
 4783
 0.16
chr4_183370400_183371073 0.30 TENM3
 teneurin transmembrane protein 3
 584
 0.84
chr16_73247873_73248024 0.30 C16orf47
 chromosome 16 open reading frame 47
 69602
 0.13
chr5_72715930_72716106 0.30 FOXD1
 forkhead box D1
 28334
 0.19
chr3_100711576_100712203 0.29 ABI3BP
 ABI family, member 3 (NESH) binding protein
 408
 0.89
chr2_12861553_12861813 0.29 TRIB2
 tribbles pseudokinase 2
 3319
 0.32
chr6_109397451_109397602 0.29 ENSG00000199944
 .
 16709
 0.17
chr5_91941448_91941599 0.29 ENSG00000221810
 .
 111697
 0.07
chr11_121970015_121970287 0.29 ENSG00000207971
 .
 401
 0.72

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4 1.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 1.0 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.3 1.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.2 0.6 GO:0035583 sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2 0.6 GO:0031223 auditory behavior(GO:0031223)
0.2 0.5 GO:0048149 behavioral response to ethanol(GO:0048149)
0.2 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.5 GO:0060839 endothelial cell fate commitment(GO:0060839)
0.1 0.6 GO:0009169 purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.4 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1 0.5 GO:0010837 regulation of keratinocyte proliferation(GO:0010837)
0.1 0.4 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1 0.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.1 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.1 0.1 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1 0.6 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.1 0.3 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0008354 germ cell migration(GO:0008354)
0.1 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.2 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1 0.3 GO:0060596 mammary placode formation(GO:0060596)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.3 GO:0001778 plasma membrane repair(GO:0001778)
0.1 0.3 GO:0032236 obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1 0.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.1 0.3 GO:0060426 lung vasculature development(GO:0060426)
0.1 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.0 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.1 0.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.3 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0060677 ureteric bud elongation(GO:0060677)
0.1 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.2 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 0.3 GO:0008218 bioluminescence(GO:0008218)
0.1 0.3 GO:0043497 regulation of protein heterodimerization activity(GO:0043497)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.2 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 1.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.2 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine development(GO:0060998) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1 0.2 GO:0010766 negative regulation of sodium ion transport(GO:0010766)
0.1 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.3 GO:0072048 pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1 0.1 GO:0035929 steroid hormone secretion(GO:0035929) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.1 0.2 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 0.4 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.1 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.1 0.2 GO:0008347 glial cell migration(GO:0008347)
0.1 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.1 0.3 GO:0048539 bone marrow development(GO:0048539)
0.1 0.3 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1 0.1 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.5 GO:0031000 response to caffeine(GO:0031000)
0.1 0.2 GO:0070141 response to UV-A(GO:0070141)
0.1 0.2 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 0.3 GO:0016246 RNA interference(GO:0016246)
0.1 0.2 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 0.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.5 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.2 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.1 GO:1900120 regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1 0.2 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 0.2 GO:1903332 regulation of protein folding(GO:1903332)
0.1 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0045989 positive regulation of striated muscle contraction(GO:0045989)
0.0 0.3 GO:0021955 central nervous system neuron axonogenesis(GO:0021955)
0.0 0.6 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.0 GO:0051584 regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.2 GO:0060390 regulation of SMAD protein import into nucleus(GO:0060390)
0.0 0.2 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.3 GO:0090399 replicative senescence(GO:0090399)
0.0 0.1 GO:0045636 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.6 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.3 GO:0009103 lipopolysaccharide biosynthetic process(GO:0009103)
0.0 0.3 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 1.1 GO:0051101 regulation of DNA binding(GO:0051101)
0.0 0.3 GO:0015871 choline transport(GO:0015871)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.1 GO:0032230 positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0 0.1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0071731 response to nitric oxide(GO:0071731)
0.0 0.1 GO:0046639 negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0048840 otolith development(GO:0048840)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.0 GO:0003211 cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.1 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.1 GO:0060992 response to fungicide(GO:0060992)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.0 GO:2000300 regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.0 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0002887 negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0002669 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.0 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0070296 sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0 0.4 GO:0035329 hippo signaling(GO:0035329)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.2 GO:0007616 long-term memory(GO:0007616)
0.0 0.1 GO:0097094 cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.0 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:0097384 cellular lipid biosynthetic process(GO:0097384)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.4 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.4 GO:0032330 regulation of chondrocyte differentiation(GO:0032330)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0032288 myelin assembly(GO:0032288)
0.0 0.1 GO:0046607 positive regulation of centrosome cycle(GO:0046607)
0.0 0.1 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.0 0.1 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0045906 negative regulation of vasoconstriction(GO:0045906)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0 0.1 GO:1903054 regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0 0.1 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.0 0.1 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0060754 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:1904063 negative regulation of cation transmembrane transport(GO:1904063)
0.0 0.1 GO:0021570 rhombomere 4 development(GO:0021570)
0.0 0.1 GO:0032410 negative regulation of transporter activity(GO:0032410)
0.0 0.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0 0.2 GO:0042745 circadian sleep/wake cycle(GO:0042745)
0.0 0.0 GO:0051459 corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.0 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0010717 regulation of epithelial to mesenchymal transition(GO:0010717)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.1 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.0 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.1 GO:0043954 cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0 0.1 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0031167 rRNA methylation(GO:0031167)
0.0 0.2 GO:0035510 DNA dealkylation(GO:0035510)
0.0 0.1 GO:0072583 synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0 0.1 GO:0045920 negative regulation of exocytosis(GO:0045920)
0.0 0.1 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.0 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 0.0 GO:0072172 ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.0 0.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0 0.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.0 GO:0032714 negative regulation of interleukin-5 production(GO:0032714)
0.0 0.1 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.0 0.0 GO:0014821 phasic smooth muscle contraction(GO:0014821)
0.0 0.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:0071436 sodium ion export(GO:0071436)
0.0 0.5 GO:0051925 obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0 0.1 GO:0043113 receptor clustering(GO:0043113)
0.0 0.1 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.0 GO:0014820 tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 0.0 GO:0071371 cellular response to gonadotropin stimulus(GO:0071371)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0060039 pericardium development(GO:0060039)
0.0 0.0 GO:1901881 positive regulation of protein depolymerization(GO:1901881)
0.0 0.1 GO:0044065 regulation of respiratory system process(GO:0044065)
0.0 0.3 GO:0014032 neural crest cell development(GO:0014032)
0.0 0.1 GO:0042693 muscle cell fate commitment(GO:0042693)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.0 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.0 0.2 GO:0030865 cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0 0.2 GO:0032964 collagen biosynthetic process(GO:0032964)
0.0 0.1 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0007494 midgut development(GO:0007494)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.0 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:0042474 middle ear morphogenesis(GO:0042474)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0060013 righting reflex(GO:0060013)
0.0 0.3 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.1 GO:0001696 gastric acid secretion(GO:0001696)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.0 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.0 GO:0014848 urinary tract smooth muscle contraction(GO:0014848)
0.0 0.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:0010560 positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.1 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0021615 glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 0.2 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.0 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.1 GO:0001974 blood vessel remodeling(GO:0001974)
0.0 0.0 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0007567 parturition(GO:0007567)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0048661 positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.0 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.0 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0 0.0 GO:0032109 positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0008038 neuron recognition(GO:0008038)
0.0 0.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0006448 regulation of translational elongation(GO:0006448)
0.0 0.0 GO:0009189 deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0 0.0 GO:0006927 obsolete transformed cell apoptotic process(GO:0006927)
0.0 0.2 GO:0007340 acrosome reaction(GO:0007340)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0042640 anagen(GO:0042640)
0.0 0.4 GO:0001764 neuron migration(GO:0001764)
0.0 0.2 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.0 0.0 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.1 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.0 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.1 GO:0044091 membrane biogenesis(GO:0044091)
0.0 0.2 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 0.0 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.0 0.0 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.0 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.1 GO:0009147 pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0 0.1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0 0.0 GO:0032730 interleukin-1 alpha production(GO:0032610) regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0 0.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.0 GO:0003079 obsolete positive regulation of natriuresis(GO:0003079)
0.0 0.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0048535 lymph node development(GO:0048535)
0.0 0.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.0 GO:0061217 positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0006554 lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0 0.0 GO:0070527 negative regulation of plasminogen activation(GO:0010757) platelet aggregation(GO:0070527)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0008595 blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.0 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.0 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.0 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.0 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.0 GO:0061525 hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0 0.2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0032459 regulation of protein oligomerization(GO:0032459)
0.0 0.0 GO:0042161 plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) negative regulation of lipoprotein metabolic process(GO:0050748)
0.0 0.3 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0010001 glial cell differentiation(GO:0010001)
0.0 0.2 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.0 GO:0010657 muscle cell apoptotic process(GO:0010657) regulation of muscle cell apoptotic process(GO:0010660)
0.0 0.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.0 GO:0043537 negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0 0.0 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
0.0 0.0 GO:0061046 regulation of branching involved in lung morphogenesis(GO:0061046)
0.0 0.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0032506 cytokinetic process(GO:0032506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.0 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.3 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0001527 microfibril(GO:0001527)
0.1 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.4 GO:0005915 zonula adherens(GO:0005915)
0.1 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.3 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.4 GO:0044291 intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.4 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0098636 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0000300 obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0 0.5 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.5 GO:0005581 collagen trimer(GO:0005581)
0.0 0.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0032059 bleb(GO:0032059)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0030016 myofibril(GO:0030016)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0032589 neuron projection membrane(GO:0032589)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.0 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 3.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.0 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.0 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0031512 motile primary cilium(GO:0031512)
0.0 0.0 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.0 GO:0031501 mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 1.0 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.2 GO:0043195 terminal bouton(GO:0043195)
0.0 0.0 GO:0043218 compact myelin(GO:0043218)
0.0 0.1 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.2 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 1.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.9 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.3 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.8 GO:0003706 obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0017166 vinculin binding(GO:0017166)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.3 GO:0005499 vitamin D binding(GO:0005499)
0.1 2.6 GO:0005518 collagen binding(GO:0005518)
0.1 0.3 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 1.1 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.6 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0051378 serotonin binding(GO:0051378)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0055106 ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0070696 transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0030172 troponin C binding(GO:0030172)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.4 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.1 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.2 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.3 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.0 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0030971 receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0 0.1 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.1 GO:0016595 glutamate binding(GO:0016595)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0016565 obsolete general transcriptional repressor activity(GO:0016565)
0.0 0.0 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0046970 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.0 0.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031)
0.0 0.2 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0004470 malic enzyme activity(GO:0004470)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.1 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.1 GO:0001228 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.1 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.4 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.0 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.0 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 1.1 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.0 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.0 GO:0045545 syndecan binding(GO:0045545)
0.0 0.0 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.0 GO:0015106 bicarbonate transmembrane transporter activity(GO:0015106)
0.0 0.0 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.2 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.0 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.0 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.4 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.1 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.6 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID BMP PATHWAY BMP receptor signaling
0.0 0.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.8 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.1 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.2 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.1 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.1 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.1 0.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 0.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.0 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)