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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for LHX2

Z-value: 2.18

Motif logo

Transcription factors associated with LHX2

Gene Symbol	Gene ID	Gene Info
LHX2 Ensembl NCBI GeneCards UniProt	ENSG00000106689.6	LHX2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
LHX2	chr9_126759855_126760197	3923	0.195546	-0.63	7.0e-02	Click!
LHX2	chr9_126773746_126773955	39	0.947237	-0.51	1.6e-01	Click!
LHX2	chr9_126774768_126775305	400	0.790921	-0.47	2.1e-01	Click!
LHX2	chr9_126781132_126781283	3531	0.195483	-0.45	2.2e-01	Click!
LHX2	chr9_126777225_126777376	376	0.829399	-0.35	3.6e-01	Click!

Activity of the LHX2 motif across conditions

Conditions sorted by the z-value of the LHX2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr6_148829582_148830289	0.82	ENSG00000223322	.	15441	0.29
chr7_93550787_93551002	0.71	GNG11	guanine nucleotide binding protein (G protein), gamma 11	117	0.96
chr4_54063057_54063462	0.69	ENSG00000207385	.	68475	0.13
chr14_45433796_45433989	0.68	FAM179B	family with sequence similarity 179, member B	2450	0.23
chr15_48935948_48936126	0.67	FBN1	fibrillin 1	1881	0.46
chr4_114898942_114899097	0.64	ARSJ	arylsulfatase family, member J	1133	0.61
chr11_132863892_132864419	0.62	OPCML	opioid binding protein/cell adhesion molecule-like	50492	0.18
chr8_89338531_89338740	0.61	RP11-586K2.1		430	0.76
chr6_85470567_85470756	0.58	TBX18	T-box 18	2412	0.42
chr10_128249841_128250268	0.58	ENSG00000221717	.	4421	0.3
chr4_81191052_81191243	0.56	FGF5	fibroblast growth factor 5	3354	0.31
chr13_103478539_103479046	0.56	ENSG00000222301	.	6449	0.13
chr7_94025506_94025990	0.55	COL1A2	collagen, type I, alpha 2	1875	0.46
chr22_45900582_45901194	0.55	FBLN1	fibulin 1	1962	0.36
chr11_12529707_12530128	0.55	PARVA	parvin, alpha	55635	0.15
chr4_4494063_4494282	0.54	STX18-IT1	STX18 intronic transcript 1 (non-protein coding)	10745	0.21
chr2_175710742_175710893	0.54	CHN1	chimerin 1	316	0.93
chr11_36252522_36252860	0.53	COMMD9	COMM domain containing 9	58283	0.13
chr4_160170135_160170337	0.51	RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	17797	0.23
chr6_130392038_130392189	0.51	L3MBTL3	l(3)mbt-like 3 (Drosophila)	50411	0.15
chr4_138449879_138450179	0.51	PCDH18	protocadherin 18	3536	0.4
chr13_100225293_100225444	0.50	CLYBL	citrate lyase beta like	33551	0.14
chr4_99578140_99578845	0.50	TSPAN5	tetraspanin 5	294	0.89
chr2_229517064_229517215	0.50	ENSG00000251801	.	64550	0.15
chr2_227049788_227050011	0.50	ENSG00000263363	.	473610	0.01
chr3_115961041_115961192	0.50	LSAMP-AS1	LSAMP antisense RNA 1	117755	0.07
chr12_59310321_59310512	0.49	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	2052	0.37
chr22_36235496_36235773	0.48	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	631	0.82
chr7_16709331_16709660	0.48	BZW2	basic leucine zipper and W2 domains 2	7737	0.2
chr15_96885905_96886056	0.47	ENSG00000222651	.	9490	0.16
chr12_26147598_26147778	0.47	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	249	0.94
chr8_93082068_93082219	0.47	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	1472	0.57
chr12_43741404_43741555	0.46	ENSG00000215993	.	56096	0.16
chr15_42749459_42749764	0.46	ZNF106	zinc finger protein 106	100	0.96
chr17_13503089_13503240	0.46	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	2080	0.42
chr5_95068559_95068710	0.46	CTD-2154I11.2		635	0.64
chr4_121990444_121990801	0.46	NDNF	neuron-derived neurotrophic factor	2534	0.31
chr4_86790910_86791061	0.45	ENSG00000265774	.	40711	0.17
chr4_77611462_77611724	0.45	AC107072.2		52817	0.12
chr12_59312115_59312531	0.45	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	1004	0.56
chr2_33822690_33822841	0.45	FAM98A	family with sequence similarity 98, member A	1579	0.47
chr19_13137194_13137536	0.44	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	1554	0.23
chr1_117636227_117636430	0.44	ENSG00000215930	.	937	0.49
chr18_74409526_74409726	0.44	ENSG00000252097	.	103104	0.07
chr1_196621837_196622284	0.43	CFH	complement factor H	874	0.67
chr2_219435462_219435613	0.43	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	1939	0.2
chr6_86159887_86160764	0.43	NT5E	5'-nucleotidase, ecto (CD73)	498	0.87
chr13_33779104_33779430	0.42	STARD13	StAR-related lipid transfer (START) domain containing 13	876	0.67
chr8_116675050_116675578	0.42	TRPS1	trichorhinophalangeal syndrome I	1409	0.6
chr14_101294075_101294314	0.42	AL117190.2		1343	0.15
chr11_91714959_91715138	0.42	FAT3	FAT atypical cadherin 3	370214	0.01
chr3_157157796_157157947	0.41	PTX3	pentraxin 3, long	3293	0.33
chr17_76036766_76037651	0.41	TNRC6C	trinucleotide repeat containing 6C	80	0.97
chr1_201509442_201509672	0.41	CSRP1	cysteine and glycine-rich protein 1	30973	0.13
chr10_69832583_69833003	0.41	HERC4	HECT and RLD domain containing E3 ubiquitin protein ligase 4	1101	0.53
chr1_119521934_119522435	0.41	TBX15	T-box 15	8244	0.28
chr10_90041933_90042089	0.41	ENSG00000200891	.	287559	0.01
chrX_34671991_34672311	0.40	TMEM47	transmembrane protein 47	3254	0.41
chr7_15723235_15723386	0.40	MEOX2	mesenchyme homeobox 2	3127	0.32
chr11_122050333_122050506	0.40	ENSG00000207994	.	27403	0.16
chrX_115371447_115371702	0.40	AGTR2	angiotensin II receptor, type 2	69599	0.13
chr22_29489752_29489903	0.40	CTA-747E2.10		17844	0.13
chr1_179111271_179111703	0.40	ABL2	c-abl oncogene 2, non-receptor tyrosine kinase	692	0.72
chr12_20525245_20525493	0.39	RP11-284H19.1		2173	0.35
chr15_81073340_81073491	0.39	KIAA1199	KIAA1199	1703	0.42
chr5_172753672_172753903	0.39	STC2	stanniocalcin 2	13	0.98
chr13_24778161_24778312	0.39	ENSG00000252695	.	41681	0.13
chr16_69478979_69479169	0.39	CYB5B	cytochrome b5 type B (outer mitochondrial membrane)	20388	0.15
chr10_728995_729174	0.39	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	6522	0.18
chr21_32715523_32716836	0.39	TIAM1	T-cell lymphoma invasion and metastasis 1	415	0.91
chr10_70321971_70322188	0.39	TET1	tet methylcytosine dioxygenase 1	1666	0.36
chr1_70818696_70818847	0.39	ANKRD13C	ankyrin repeat domain 13C	1634	0.29
chr12_18449684_18450065	0.39	PIK3C2G	phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma	14896	0.31
chr21_37312564_37312715	0.39	FKSG68		41912	0.14
chr17_63549735_63549886	0.39	AXIN2	axin 2	5037	0.32
chr3_79066759_79066910	0.39	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	860	0.75
chr5_102209163_102209314	0.39	PAM	peptidylglycine alpha-amidating monooxygenase	7418	0.33
chr12_91575190_91575391	0.39	DCN	decorin	537	0.85
chr17_18090882_18091033	0.39	RP11-258F1.1		2890	0.16
chr12_91576386_91576586	0.38	DCN	decorin	0	0.99
chr1_247611615_247612128	0.38	OR2B11	olfactory receptor, family 2, subfamily B, member 11	3437	0.2
chr11_19736431_19736825	0.38	NAV2	neuron navigator 2	1485	0.49
chr3_157158697_157158863	0.38	PTX3	pentraxin 3, long	4202	0.3
chr10_120031586_120031737	0.38	FAM204A	family with sequence similarity 204, member A	70091	0.13
chr16_64450080_64450292	0.38	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	643395	0.0
chr16_59668238_59668389	0.38	ENSG00000200062	.	94283	0.09
chr1_34629900_34630098	0.38	CSMD2	CUB and Sushi multiple domains 2	876	0.55
chr10_33670460_33670611	0.38	NRP1	neuropilin 1	45345	0.19
chr7_137028318_137028638	0.38	PTN	pleiotrophin	42	0.99
chr10_30504590_30504756	0.37	ENSG00000200887	.	83929	0.09
chr1_156087932_156088663	0.37	LMNA	lamin A/C	3784	0.13
chr11_119292436_119293234	0.37	THY1	Thy-1 cell surface antigen	437	0.74
chr4_122077287_122077641	0.37	TNIP3	TNFAIP3 interacting protein 3	8031	0.23
chr13_45146263_45146555	0.37	TSC22D1	TSC22 domain family, member 1	3983	0.32
chr9_98335013_98335164	0.37	PTCH1	patched 1	55749	0.12
chr10_33622034_33622426	0.37	NRP1	neuropilin 1	1080	0.63
chr2_238322401_238322657	0.37	COL6A3	collagen, type VI, alpha 3	262	0.93
chr8_24366535_24366686	0.37	RP11-561E1.1		5491	0.24
chr18_32075591_32075742	0.36	DTNA	dystrobrevin, alpha	1799	0.52
chr13_91965562_91965713	0.36	ENSG00000215417	.	37222	0.22
chr3_134091064_134091340	0.36	AMOTL2	angiomotin like 2	448	0.85
chr6_148831295_148831530	0.36	ENSG00000223322	.	13964	0.3
chr3_29566924_29567075	0.36	RBMS3-AS2	RBMS3 antisense RNA 2	91547	0.09
chr6_128841955_128842296	0.36	PTPRK	protein tyrosine phosphatase, receptor type, K	255	0.91
chr2_40591154_40591305	0.36	SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1	66191	0.13
chr2_227658547_227658788	0.36	IRS1	insulin receptor substrate 1	5808	0.22
chr15_57509304_57509455	0.36	TCF12	transcription factor 12	2249	0.41
chr21_17497567_17497931	0.36	ENSG00000252273	.	89920	0.1
chr15_37395216_37395447	0.35	MEIS2	Meis homeobox 2	1827	0.38
chr1_54232654_54232848	0.35	ENSG00000201003	.	4075	0.22
chr6_18749403_18749554	0.35	ENSG00000207775	.	177463	0.03
chr1_162791853_162792918	0.35	HSD17B7	hydroxysteroid (17-beta) dehydrogenase 7	31806	0.15
chr5_71543858_71544009	0.35	ENSG00000244748	.	66582	0.09
chr18_10059803_10059983	0.35	ENSG00000263630	.	54699	0.15
chr7_94026391_94026542	0.35	COL1A2	collagen, type I, alpha 2	2593	0.39
chr14_52122431_52122582	0.35	FRMD6	FERM domain containing 6	3808	0.24
chr11_108766543_108766821	0.35	ENSG00000201243	.	109562	0.07
chr9_17005379_17005546	0.35	ENSG00000241152	.	48437	0.18
chr9_99277013_99277426	0.35	CDC14B	cell division cycle 14B	51893	0.13
chr3_29327656_29328192	0.35	RBMS3-AS3	RBMS3 antisense RNA 3	4293	0.26
chr6_127836184_127836541	0.35	SOGA3	SOGA family member 3	1397	0.51
chr7_120726405_120726556	0.34	ENSG00000212628	.	2613	0.31
chr18_53070200_53070424	0.34	TCF4	transcription factor 4	625	0.79
chr7_83822532_83822694	0.34	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	1604	0.57
chr12_54672073_54672366	0.34	CBX5	chromobox homolog 5	1667	0.15
chr1_223895189_223895645	0.34	CAPN2	calpain 2, (m/II) large subunit	4617	0.23
chr6_132269338_132269679	0.34	RP11-69I8.3		2578	0.29
chr11_89938699_89938850	0.34	CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	3872	0.31
chr5_158426214_158426386	0.34	CTD-2363C16.2		13486	0.22
chr4_38011358_38011509	0.34	TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	17976	0.25
chr18_32291325_32291476	0.34	DTNA	dystrobrevin, alpha	1139	0.62
chr14_67878511_67879217	0.34	PLEK2	pleckstrin 2	53	0.97
chr4_159041557_159041708	0.34	FAM198B	family with sequence similarity 198, member B	39201	0.16
chr17_48295929_48296104	0.34	COL1A1	collagen, type I, alpha 1	17023	0.11
chr11_124513856_124514050	0.33	ENSG00000200278	.	7598	0.12
chr5_15510117_15510353	0.33	FBXL7	F-box and leucine-rich repeat protein 7	8688	0.31
chr15_48936207_48936433	0.33	FBN1	fibrillin 1	1598	0.51
chr9_16869648_16869822	0.33	BNC2	basonuclin 2	969	0.71
chr7_95704908_95705546	0.33	ENSG00000208025	.	143841	0.04
chr8_122650853_122651057	0.33	HAS2-AS1	HAS2 antisense RNA 1	578	0.78
chr6_57035944_57036095	0.33	RP11-203B9.4		172	0.92
chr13_33896904_33897055	0.33	ENSG00000264288	.	14130	0.21
chr11_94527493_94527644	0.33	AMOTL1	angiomotin like 1	26031	0.2
chr1_215130950_215131319	0.33	KCNK2	potassium channel, subfamily K, member 2	48064	0.2
chr7_28312230_28312417	0.33	CREB5	cAMP responsive element binding protein 5	26617	0.2
chr10_95813368_95813519	0.33	ENSG00000252895	.	6561	0.2
chr8_67522944_67523356	0.33	MYBL1	v-myb avian myeloblastosis viral oncogene homolog-like 1	1992	0.31
chr20_4953796_4953984	0.32	SLC23A2	solute carrier family 23 (ascorbic acid transporter), member 2	28255	0.16
chr2_104572278_104572429	0.32	ENSG00000199727	.	576878	0.0
chr14_45711437_45711895	0.32	MIS18BP1	MIS18 binding protein 1	10714	0.2
chr12_78078846_78079000	0.32	AC073528.1		128355	0.06
chr2_200446222_200446758	0.32	SATB2	SATB homeobox 2	110501	0.07
chr11_23919257_23919465	0.32	ENSG00000252519	.	48037	0.2
chr6_159360525_159360963	0.32	ENSG00000223191	.	13141	0.19
chr16_89990965_89991193	0.32	TUBB3	Tubulin beta-3 chain	1305	0.26
chr20_42667406_42667585	0.32	TOX2	TOX high mobility group box family member 2	15496	0.21
chr3_87036535_87037613	0.32	VGLL3	vestigial like 3 (Drosophila)	2778	0.42
chr12_21926599_21927146	0.32	KCNJ8	potassium inwardly-rectifying channel, subfamily J, member 8	883	0.57
chr5_16713364_16713515	0.32	MYO10	myosin X	25057	0.21
chr1_42383823_42384248	0.31	HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	134	0.98
chr1_215181172_215181323	0.31	KCNK2	potassium channel, subfamily K, member 2	2049	0.5
chr7_92327766_92328157	0.31	ENSG00000206763	.	3167	0.33
chr10_7914212_7914417	0.31	TAF3	TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa	53847	0.14
chr1_224805331_224805508	0.31	CNIH3	cornichon family AMPA receptor auxiliary protein 3	1424	0.35
chr7_121078096_121078495	0.31	FAM3C	family with sequence similarity 3, member C	41877	0.19
chr16_15588070_15588221	0.31	C16orf45	chromosome 16 open reading frame 45	7978	0.23
chr1_48174846_48175814	0.31	FLJ00388		51960	0.16
chr2_230138192_230138530	0.31	PID1	phosphotyrosine interaction domain containing 1	2360	0.4
chr6_148664293_148664728	0.31	SASH1	SAM and SH3 domain containing 1	781	0.74
chr9_118915780_118915931	0.31	PAPPA	pregnancy-associated plasma protein A, pappalysin 1	228	0.95
chr15_99297407_99297593	0.31	ENSG00000264480	.	30155	0.19
chr8_40011594_40011745	0.31	C8orf4	chromosome 8 open reading frame 4	680	0.81
chr14_30696659_30696810	0.31	PRKD1	protein kinase D1	35630	0.23
chr12_127568278_127568473	0.31	ENSG00000239776	.	82297	0.12
chr6_152701966_152702349	0.31	SYNE1-AS1	SYNE1 antisense RNA 1	476	0.79
chr2_161767569_161767862	0.31	ENSG00000244372	.	33657	0.24
chr18_7617915_7618177	0.30	PTPRM	protein tyrosine phosphatase, receptor type, M	50229	0.16
chr7_114055046_114055222	0.30	FOXP2	forkhead box P2	21	0.98
chr4_20420225_20420376	0.30	SLIT2-IT1	SLIT2 intronic transcript 1 (non-protein coding)	26488	0.25
chr12_95868834_95869163	0.30	METAP2	methionyl aminopeptidase 2	1060	0.55
chr13_36047277_36047487	0.30	MAB21L1	mab-21-like 1 (C. elegans)	3450	0.24
chr10_95802235_95802386	0.30	ENSG00000252895	.	4572	0.22
chr1_178602075_178602251	0.30	ENSG00000266417	.	44721	0.13
chr12_2162213_2162837	0.30	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	61	0.97
chr12_91487813_91488090	0.30	LUM	lumican	17657	0.21
chr15_57978292_57978443	0.30	POLR2M	polymerase (RNA) II (DNA directed) polypeptide M	20460	0.23
chr15_37176117_37176447	0.30	ENSG00000212511	.	31441	0.23
chr8_121137253_121137925	0.30	COL14A1	collagen, type XIV, alpha 1	237	0.96
chr9_112942337_112942488	0.30	C9orf152	chromosome 9 open reading frame 152	28057	0.2
chr1_164534283_164534434	0.30	PBX1	pre-B-cell leukemia homeobox 1	2316	0.4
chr1_100232300_100232564	0.30	FRRS1	ferric-chelate reductase 1	1083	0.49
chr3_15369209_15369360	0.30	SH3BP5	SH3-domain binding protein 5 (BTK-associated)	4783	0.16
chr4_183370400_183371073	0.30	TENM3	teneurin transmembrane protein 3	584	0.84
chr16_73247873_73248024	0.30	C16orf47	chromosome 16 open reading frame 47	69602	0.13
chr5_72715930_72716106	0.30	FOXD1	forkhead box D1	28334	0.19
chr3_100711576_100712203	0.29	ABI3BP	ABI family, member 3 (NESH) binding protein	408	0.89
chr2_12861553_12861813	0.29	TRIB2	tribbles pseudokinase 2	3319	0.32
chr6_109397451_109397602	0.29	ENSG00000199944	.	16709	0.17
chr5_91941448_91941599	0.29	ENSG00000221810	.	111697	0.07
chr11_121970015_121970287	0.29	ENSG00000207971	.	401	0.72

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.4	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.4	1.6	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3	1.0	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.3	1.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.2	0.6	GO:0035583	sequestering of extracellular ligand from receptor(GO:0035581) sequestering of TGFbeta in extracellular matrix(GO:0035583) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.2	0.6	GO:0031223	auditory behavior(GO:0031223)
0.2	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.2	0.2	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2	0.5	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.1	0.6	GO:0009169	purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1	0.4	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.5	GO:0010837	regulation of keratinocyte proliferation(GO:0010837)
0.1	0.4	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.1	0.4	GO:0055098	response to low-density lipoprotein particle(GO:0055098)
0.1	0.1	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	0.5	GO:0051497	negative regulation of stress fiber assembly(GO:0051497)
0.1	0.1	GO:0003402	planar cell polarity pathway involved in axis elongation(GO:0003402)
0.1	0.6	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.1	0.3	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.1	0.4	GO:0008354	germ cell migration(GO:0008354)
0.1	0.2	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.1	0.2	GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.1	0.3	GO:0060596	mammary placode formation(GO:0060596)
0.1	0.5	GO:0048251	elastic fiber assembly(GO:0048251)
0.1	0.4	GO:0001757	somite specification(GO:0001757)
0.1	0.3	GO:0001778	plasma membrane repair(GO:0001778)
0.1	0.3	GO:0032236	obsolete positive regulation of calcium ion transport via store-operated calcium channel activity(GO:0032236)
0.1	0.2	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.1	0.3	GO:0046549	retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1	0.1	GO:0048845	venous blood vessel morphogenesis(GO:0048845)
0.1	0.3	GO:0060426	lung vasculature development(GO:0060426)
0.1	0.2	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.1	1.0	GO:0045880	positive regulation of smoothened signaling pathway(GO:0045880)
0.1	0.4	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1	0.3	GO:0060242	contact inhibition(GO:0060242)
0.1	0.2	GO:0060677	ureteric bud elongation(GO:0060677)
0.1	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.1	0.2	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.1	0.3	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.1	1.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	0.3	GO:0008218	bioluminescence(GO:0008218)
0.1	0.3	GO:0043497	regulation of protein heterodimerization activity(GO:0043497)
0.1	0.2	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.1	0.1	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.6	GO:0060325	face morphogenesis(GO:0060325)
0.1	0.2	GO:0048742	regulation of skeletal muscle fiber development(GO:0048742)
0.1	1.7	GO:0030199	collagen fibril organization(GO:0030199)
0.1	0.2	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1	0.2	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine development(GO:0060998) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.1	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.1	0.5	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.1	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.3	GO:0072048	pattern specification involved in kidney development(GO:0061004) renal system pattern specification(GO:0072048) pattern specification involved in metanephros development(GO:0072268)
0.1	0.1	GO:0035929	steroid hormone secretion(GO:0035929) corticosteroid hormone secretion(GO:0035930) regulation of steroid hormone secretion(GO:2000831) regulation of corticosteroid hormone secretion(GO:2000846)
0.1	0.1	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.1	0.2	GO:0016199	axon midline choice point recognition(GO:0016199)
0.1	0.4	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.1	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.1	0.2	GO:0008347	glial cell migration(GO:0008347)
0.1	0.2	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.3	GO:0048539	bone marrow development(GO:0048539)
0.1	0.3	GO:0010107	potassium ion import(GO:0010107)
0.1	0.2	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.1	0.1	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.5	GO:0031000	response to caffeine(GO:0031000)
0.1	0.2	GO:0070141	response to UV-A(GO:0070141)
0.1	0.2	GO:0003099	positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.2	GO:0001955	blood vessel maturation(GO:0001955)
0.1	0.1	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.3	GO:0016246	RNA interference(GO:0016246)
0.1	0.2	GO:0070091	glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1	0.3	GO:0060259	regulation of feeding behavior(GO:0060259)
0.1	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1	0.3	GO:0060216	definitive hemopoiesis(GO:0060216)
0.1	0.5	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.1	GO:1900120	regulation of receptor binding(GO:1900120) negative regulation of receptor binding(GO:1900121)
0.1	0.2	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.1	0.2	GO:1903332	regulation of protein folding(GO:1903332)
0.1	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0045989	positive regulation of striated muscle contraction(GO:0045989)
0.0	0.3	GO:0021955	central nervous system neuron axonogenesis(GO:0021955)
0.0	0.6	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0051451	myoblast migration(GO:0051451)
0.0	0.0	GO:0051584	regulation of neurotransmitter uptake(GO:0051580) regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0	0.2	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.3	GO:0090399	replicative senescence(GO:0090399)
0.0	0.1	GO:0045636	positive regulation of melanocyte differentiation(GO:0045636) positive regulation of pigment cell differentiation(GO:0050942)
0.0	0.6	GO:0030325	adrenal gland development(GO:0030325)
0.0	0.3	GO:0009103	lipopolysaccharide biosynthetic process(GO:0009103)
0.0	0.3	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0	0.1	GO:0060999	positive regulation of dendritic spine development(GO:0060999)
0.0	1.1	GO:0051101	regulation of DNA binding(GO:0051101)
0.0	0.3	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0032230	positive regulation of synaptic transmission, GABAergic(GO:0032230)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.1	GO:0001957	intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0	0.2	GO:0071731	response to nitric oxide(GO:0071731)
0.0	0.1	GO:0046639	negative regulation of alpha-beta T cell differentiation(GO:0046639)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0048840	otolith development(GO:0048840)
0.0	0.2	GO:0008228	opsonization(GO:0008228)
0.0	0.3	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.1	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.2	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.0	GO:0003211	cardiac chamber formation(GO:0003207) cardiac ventricle formation(GO:0003211)
0.0	0.2	GO:0016264	gap junction assembly(GO:0016264)
0.0	0.1	GO:0090177	establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0	0.1	GO:0060992	response to fungicide(GO:0060992)
0.0	0.1	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.0	GO:2000300	regulation of synaptic vesicle transport(GO:1902803) regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.0	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0043032	positive regulation of macrophage activation(GO:0043032)
0.0	0.1	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.0	GO:0002887	negative regulation of myeloid leukocyte mediated immunity(GO:0002887) negative regulation of leukocyte degranulation(GO:0043301)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.1	GO:0002669	lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) positive regulation of T cell anergy(GO:0002669) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0070296	sarcoplasmic reticulum calcium ion transport(GO:0070296)
0.0	0.4	GO:0035329	hippo signaling(GO:0035329)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.2	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0050703	interleukin-1 alpha secretion(GO:0050703)
0.0	0.2	GO:0007616	long-term memory(GO:0007616)
0.0	0.1	GO:0097094	cranial suture morphogenesis(GO:0060363) craniofacial suture morphogenesis(GO:0097094)
0.0	0.3	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0046185	aldehyde catabolic process(GO:0046185)
0.0	0.1	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.0	0.0	GO:0031639	plasminogen activation(GO:0031639)
0.0	0.1	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.0	0.1	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0	0.3	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.0	GO:0097384	cellular lipid biosynthetic process(GO:0097384)
0.0	0.1	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.4	GO:0001893	maternal placenta development(GO:0001893)
0.0	0.4	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:0046607	positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0017121	phospholipid scrambling(GO:0017121)
0.0	0.1	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.0	0.1	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
0.0	0.1	GO:0007500	mesodermal cell fate determination(GO:0007500)
0.0	0.1	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.0	0.1	GO:0046952	ketone body catabolic process(GO:0046952)
0.0	0.1	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.1	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.2	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.0	0.1	GO:1903054	regulation of extracellular matrix disassembly(GO:0010715) negative regulation of extracellular matrix disassembly(GO:0010716) regulation of extracellular matrix organization(GO:1903053) negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.6	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0014912	negative regulation of smooth muscle cell migration(GO:0014912)
0.0	0.1	GO:0006011	UDP-glucose metabolic process(GO:0006011)
0.0	0.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	0.1	GO:0060754	mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0	0.2	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.0	0.1	GO:1904063	negative regulation of cation transmembrane transport(GO:1904063)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.1	GO:0032410	negative regulation of transporter activity(GO:0032410)
0.0	0.1	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.0	GO:0010511	regulation of phosphatidylinositol biosynthetic process(GO:0010511)
0.0	0.2	GO:0042745	circadian sleep/wake cycle(GO:0042745)
0.0	0.0	GO:0051459	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0	0.2	GO:0010717	regulation of epithelial to mesenchymal transition(GO:0010717)
0.0	0.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.1	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0060437	lung growth(GO:0060437)
0.0	0.0	GO:0009786	regulation of asymmetric cell division(GO:0009786)
0.0	0.1	GO:0043954	cell junction maintenance(GO:0034331) cellular component maintenance(GO:0043954) cell-cell junction maintenance(GO:0045217)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0001706	endoderm formation(GO:0001706)
0.0	0.1	GO:0031167	rRNA methylation(GO:0031167)
0.0	0.2	GO:0035510	DNA dealkylation(GO:0035510)
0.0	0.1	GO:0072583	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488) clathrin-mediated endocytosis(GO:0072583)
0.0	0.1	GO:0045920	negative regulation of exocytosis(GO:0045920)
0.0	0.1	GO:0034629	cellular protein complex localization(GO:0034629)
0.0	0.0	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.7	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.0	GO:0072172	ureteric bud formation(GO:0060676) mesonephric tubule formation(GO:0072172)
0.0	0.1	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.0	0.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.0	0.0	GO:0032714	negative regulation of interleukin-5 production(GO:0032714)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.0	GO:0014821	phasic smooth muscle contraction(GO:0014821)
0.0	0.3	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.1	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0071436	sodium ion export(GO:0071436)
0.0	0.5	GO:0051925	obsolete regulation of calcium ion transport via voltage-gated calcium channel activity(GO:0051925)
0.0	0.1	GO:0043113	receptor clustering(GO:0043113)
0.0	0.1	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.0	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.0	GO:0071371	cellular response to gonadotropin stimulus(GO:0071371)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0060039	pericardium development(GO:0060039)
0.0	0.0	GO:1901881	positive regulation of protein depolymerization(GO:1901881)
0.0	0.1	GO:0044065	regulation of respiratory system process(GO:0044065)
0.0	0.3	GO:0014032	neural crest cell development(GO:0014032)
0.0	0.1	GO:0042693	muscle cell fate commitment(GO:0042693)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865) cortical actin cytoskeleton organization(GO:0030866)
0.0	0.2	GO:0032964	collagen biosynthetic process(GO:0032964)
0.0	0.1	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.2	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.0	0.1	GO:0007494	midgut development(GO:0007494)
0.0	0.1	GO:0030219	megakaryocyte differentiation(GO:0030219)
0.0	0.0	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0042474	middle ear morphogenesis(GO:0042474)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.0	GO:0060013	righting reflex(GO:0060013)
0.0	0.3	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:0001696	gastric acid secretion(GO:0001696)
0.0	0.4	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.0	0.0	GO:0032057	negative regulation of translational initiation in response to stress(GO:0032057)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	2.2	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:0014848	urinary tract smooth muscle contraction(GO:0014848)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0010560	positive regulation of glycoprotein biosynthetic process(GO:0010560) positive regulation of glycoprotein metabolic process(GO:1903020)
0.0	0.1	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.0	GO:0021615	glossopharyngeal nerve development(GO:0021563) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0000101	sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0	0.2	GO:0045104	intermediate filament cytoskeleton organization(GO:0045104)
0.0	0.0	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
0.0	0.1	GO:0001974	blood vessel remodeling(GO:0001974)
0.0	0.0	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.0	GO:0045875	negative regulation of sister chromatid cohesion(GO:0045875)
0.0	0.1	GO:0001945	lymph vessel development(GO:0001945)
0.0	0.1	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.0	0.2	GO:0048661	positive regulation of smooth muscle cell proliferation(GO:0048661)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.0	GO:0022038	corpus callosum development(GO:0022038)
0.0	0.0	GO:0060071	Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.0	0.0	GO:0032109	positive regulation of response to extracellular stimulus(GO:0032106) positive regulation of response to nutrient levels(GO:0032109)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:0008038	neuron recognition(GO:0008038)
0.0	0.0	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.0	GO:0009189	deoxyribonucleoside diphosphate biosynthetic process(GO:0009189)
0.0	0.0	GO:0006927	obsolete transformed cell apoptotic process(GO:0006927)
0.0	0.2	GO:0007340	acrosome reaction(GO:0007340)
0.0	0.1	GO:0090116	DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0	0.0	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.0	0.1	GO:0042640	anagen(GO:0042640)
0.0	0.4	GO:0001764	neuron migration(GO:0001764)
0.0	0.2	GO:0035249	synaptic transmission, glutamatergic(GO:0035249)
0.0	0.0	GO:0046022	regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0	0.1	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.0	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.0	0.1	GO:0044091	membrane biogenesis(GO:0044091)
0.0	0.2	GO:0030520	intracellular estrogen receptor signaling pathway(GO:0030520)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0021904	dorsal/ventral neural tube patterning(GO:0021904)
0.0	0.0	GO:0032543	mitochondrial translation(GO:0032543)
0.0	0.1	GO:0010700	negative regulation of norepinephrine secretion(GO:0010700)
0.0	0.0	GO:0055089	fatty acid homeostasis(GO:0055089)
0.0	0.0	GO:0046325	negative regulation of glucose import(GO:0046325)
0.0	0.1	GO:0033137	negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0009147	pyrimidine nucleoside triphosphate metabolic process(GO:0009147)
0.0	0.1	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:0035268	protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269) mannosylation(GO:0097502)
0.0	0.0	GO:0032730	interleukin-1 alpha production(GO:0032610) regulation of interleukin-1 alpha production(GO:0032650) positive regulation of interleukin-1 alpha production(GO:0032730)
0.0	0.1	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.0	GO:0003079	obsolete positive regulation of natriuresis(GO:0003079)
0.0	0.3	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0	0.1	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0048535	lymph node development(GO:0048535)
0.0	0.0	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.1	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.0	GO:0061217	positive regulation of mesonephros development(GO:0061213) regulation of mesonephros development(GO:0061217) regulation of branching involved in ureteric bud morphogenesis(GO:0090189) positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0006554	lysine metabolic process(GO:0006553) lysine catabolic process(GO:0006554)
0.0	0.0	GO:0070527	negative regulation of plasminogen activation(GO:0010757) platelet aggregation(GO:0070527)
0.0	0.0	GO:0044314	protein K27-linked ubiquitination(GO:0044314)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0008595	blastoderm segmentation(GO:0007350) tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0	0.0	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.0	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:0043117	positive regulation of vascular permeability(GO:0043117)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.0	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.0	GO:0061525	hindgut morphogenesis(GO:0007442) hindgut development(GO:0061525)
0.0	0.2	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0032459	regulation of protein oligomerization(GO:0032459)
0.0	0.0	GO:0042161	plasma lipoprotein particle oxidation(GO:0034441) regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) negative regulation of lipoprotein metabolic process(GO:0050748)
0.0	0.3	GO:0015914	phospholipid transport(GO:0015914)
0.0	0.3	GO:0010001	glial cell differentiation(GO:0010001)
0.0	0.2	GO:0050819	negative regulation of coagulation(GO:0050819)
0.0	0.0	GO:0010657	muscle cell apoptotic process(GO:0010657) regulation of muscle cell apoptotic process(GO:0010660)
0.0	0.0	GO:0071480	cellular response to gamma radiation(GO:0071480)
0.0	0.0	GO:0043537	negative regulation of blood vessel endothelial cell migration(GO:0043537)
0.0	0.0	GO:0021513	spinal cord dorsal/ventral patterning(GO:0021513)
0.0	0.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.0	0.0	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0032506	cytokinetic process(GO:0032506)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2	2.0	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0030934	anchoring collagen complex(GO:0030934)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.3	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.4	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1	0.3	GO:0070852	cell body fiber(GO:0070852)
0.1	0.5	GO:0001527	microfibril(GO:0001527)
0.1	0.6	GO:0005614	interstitial matrix(GO:0005614)
0.1	0.3	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.1	0.2	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.4	GO:0005915	zonula adherens(GO:0005915)
0.1	0.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.1	0.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	0.3	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.1	0.2	GO:0043259	laminin-10 complex(GO:0043259)
0.1	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.3	GO:0016012	sarcoglycan complex(GO:0016012)
0.0	0.2	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.5	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0010369	chromocenter(GO:0010369)
0.0	0.4	GO:0044291	intercalated disc(GO:0014704) cell-cell contact zone(GO:0044291)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.2	GO:0008328	ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0	0.1	GO:0005787	signal peptidase complex(GO:0005787)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.4	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.7	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	0.9	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0000300	obsolete peripheral to membrane of membrane fraction(GO:0000300)
0.0	0.5	GO:0009925	basal plasma membrane(GO:0009925)
0.0	0.5	GO:0005581	collagen trimer(GO:0005581)
0.0	0.0	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0032059	bleb(GO:0032059)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	1.6	GO:0030016	myofibril(GO:0030016)
0.0	0.3	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.1	GO:0032589	neuron projection membrane(GO:0032589)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.3	GO:0005811	lipid particle(GO:0005811)
0.0	0.0	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.0	0.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.2	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.0	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	3.6	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.5	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.7	GO:0031012	extracellular matrix(GO:0031012)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.0	GO:0033268	node of Ranvier(GO:0033268)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.0	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0034704	calcium channel complex(GO:0034704)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.0	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.0	GO:0031501	mannosyltransferase complex(GO:0031501) dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	1.0	GO:0034705	potassium channel complex(GO:0034705)
0.0	0.2	GO:0043195	terminal bouton(GO:0043195)
0.0	0.0	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	0.2	GO:0016328	lateral plasma membrane(GO:0016328)
0.0	0.1	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0001098	basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.3	1.1	GO:0045499	chemorepellent activity(GO:0045499)
0.2	0.5	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.2	1.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	0.9	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.9	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.1	0.3	GO:0016842	amidine-lyase activity(GO:0016842)
0.1	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.1	0.3	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.3	GO:0043237	laminin-1 binding(GO:0043237)
0.1	0.6	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.1	0.4	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	0.8	GO:0003706	obsolete ligand-regulated transcription factor activity(GO:0003706)
0.1	0.3	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.1	0.7	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.1	0.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	0.8	GO:0070064	proline-rich region binding(GO:0070064)
0.1	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.3	GO:0005499	vitamin D binding(GO:0005499)
0.1	2.6	GO:0005518	collagen binding(GO:0005518)
0.1	0.3	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.1	0.3	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	1.1	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	0.6	GO:0030247	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1	0.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559) xenobiotic transporter activity(GO:0042910)
0.1	0.3	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.2	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.9	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.4	GO:0051378	serotonin binding(GO:0051378)
0.0	0.2	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0055106	ligase regulator activity(GO:0055103) ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.2	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.1	GO:0042805	actinin binding(GO:0042805)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016909	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.3	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.2	GO:0070696	transmembrane receptor protein serine/threonine kinase binding(GO:0070696)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.0	0.4	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.2	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.2	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.3	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0030172	troponin C binding(GO:0030172)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.3	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.2	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.4	GO:0034483	heparan sulfate sulfotransferase activity(GO:0034483)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0055077	gap junction hemi-channel activity(GO:0055077)
0.0	0.1	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) ATP-dependent microtubule motor activity(GO:1990939)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0003680	AT DNA binding(GO:0003680)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0034711	inhibin binding(GO:0034711)
0.0	0.3	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.2	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	1.7	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.0	0.2	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.3	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0008242	omega peptidase activity(GO:0008242)
0.0	0.3	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.0	0.1	GO:0004157	dihydropyrimidinase activity(GO:0004157)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.0	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0033130	acetylcholine receptor binding(GO:0033130)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.4	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0009008	DNA-methyltransferase activity(GO:0009008)
0.0	0.2	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.0	0.1	GO:0001012	RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0	0.1	GO:0016595	glutamate binding(GO:0016595)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0016565	obsolete general transcriptional repressor activity(GO:0016565)
0.0	0.0	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.5	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.2	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.4	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.0	0.2	GO:0046970	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) histone deacetylase activity (H4-K16 specific)(GO:0034739) NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0004970	ionotropic glutamate receptor activity(GO:0004970)
0.0	0.3	GO:0005031	tumor necrosis factor-activated receptor activity(GO:0005031)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.1	GO:0019238	cyclohydrolase activity(GO:0019238)
0.0	0.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0019863	IgE binding(GO:0019863)
0.0	0.7	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	0.1	GO:0001228	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.1	GO:0004407	histone deacetylase activity(GO:0004407)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.1	GO:0050780	dopamine receptor binding(GO:0050780)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0015184	L-cystine transmembrane transporter activity(GO:0015184)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.2	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.4	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.0	0.1	GO:0005497	androgen binding(GO:0005497)
0.0	0.1	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.0	0.2	GO:0051018	protein kinase A binding(GO:0051018)
0.0	0.1	GO:0005243	gap junction channel activity(GO:0005243)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	1.1	GO:0008201	heparin binding(GO:0008201)
0.0	0.1	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.0	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.1	GO:0035173	histone kinase activity(GO:0035173)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.0	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.1	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0	0.0	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0004945	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	0.2	GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.0	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.0	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0045545	syndecan binding(GO:0045545)
0.0	0.0	GO:0016623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.0	GO:0001601	peptide YY receptor activity(GO:0001601)
0.0	0.0	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.0	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.2	GO:0017046	peptide hormone binding(GO:0017046)
0.0	0.0	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.4	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.1	0.7	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	2.2	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.1	0.1	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.0	0.8	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.7	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.8	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.9	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.0	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.2	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.7	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.2	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.3	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.2	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling
0.0	0.2	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.8	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.5	PID SHP2 PATHWAY	SHP2 signaling
0.0	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.0	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	0.0	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	1.4	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	0.1	REACTOME GPCR LIGAND BINDING	Genes involved in GPCR ligand binding
0.1	1.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	2.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.1	0.2	REACTOME SHC MEDIATED SIGNALLING	Genes involved in SHC-mediated signalling
0.1	0.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	0.1	REACTOME DOWNSTREAM TCR SIGNALING	Genes involved in Downstream TCR signaling
0.1	0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.1	0.4	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.1	0.1	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.1	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	1.0	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	0.6	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	1.1	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.5	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.3	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.0	0.0	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.6	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.0	1.0	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.4	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.3	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.7	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.3	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.1	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.3	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0	0.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.0	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.0	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.4	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.5	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME GRB2 EVENTS IN ERBB2 SIGNALING	Genes involved in GRB2 events in ERBB2 signaling
0.0	0.3	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.7	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.2	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.0	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.1	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.1	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.0	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)