Project
ENCODE: H3K4me3 ChIP-Seq of primary human cells
Navigation
Downloads
Logo

Results for MAFA

Z-value: 1.01

Motif logo

logo of

Transcription factors associated with MAFA

Gene Symbol Gene ID Gene Info
MAFA
ENSG00000182759.3 MAF bZIP transcription factor A

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr8_144510266_144510417MAFA22350.1833250.771.4e-02Click!
chr8_144543935_144544113MAFA314480.0847460.761.8e-02Click!
chr8_144544411_144544712MAFA319850.0839520.723.0e-02Click!
chr8_144510497_144510807MAFA19240.2074470.713.4e-02Click!
chr8_144544755_144544972MAFA322870.0835040.713.4e-02Click!

Activity of the MAFA motif across conditions

Conditions sorted by the z-value of the MAFA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr5_40684769_40685057 0.56 PTGER4
 prostaglandin E receptor 4 (subtype EP4)
 5313
 0.23
chr14_100533458_100533776 0.53 EVL
 Enah/Vasp-like
 843
 0.55
chr16_27414444_27414647 0.48 IL21R
 interleukin 21 receptor
 122
 0.97
chrY_7207933_7208104 0.46 ENSG00000251996
 .
 1554
 0.4
chr7_150148386_150148563 0.46 GIMAP8
 GTPase, IMAP family member 8
 756
 0.63
chr10_6621928_6622130 0.39 PRKCQ
 protein kinase C, theta
 172
 0.98
chr14_69095479_69095684 0.39 CTD-2325P2.4
419
 0.89
chr16_87799045_87799225 0.39 KLHDC4
 kelch domain containing 4
 370
 0.86
chr16_3628507_3629057 0.39 NLRC3
 NLR family, CARD domain containing 3
 1381
 0.35
chr3_81545471_81545622 0.38 ENSG00000222389
 .
 13081
 0.32
chr13_99222825_99223522 0.37 STK24
 serine/threonine kinase 24
 5944
 0.22
chr16_89788020_89788196 0.36 ZNF276
 zinc finger protein 276
 156
 0.84
chr11_16946573_16946796 0.35 PLEKHA7
 pleckstrin homology domain containing, family A member 7
 43779
 0.12
chr1_145440326_145440711 0.35 TXNIP
 thioredoxin interacting protein
 1212
 0.33
chr19_6501621_6501878 0.34 TUBB4A
 tubulin, beta 4A class IVa
 49
 0.95
chrX_123481094_123481375 0.34 SH2D1A
 SH2 domain containing 1A
 795
 0.78
chr17_76123138_76123289 0.34 TMC6
 transmembrane channel-like 6
 112
 0.94
chr8_134080772_134080923 0.34 SLA
 Src-like-adaptor
 8244
 0.25
chr19_49931722_49931873 0.33 GFY
 golgi-associated, olfactory signaling regulator
 4791
 0.07
chr1_36272671_36272822 0.32 AGO4
 argonaute RISC catalytic component 4
 1027
 0.53
chr9_503761_503951 0.32 KANK1
 KN motif and ankyrin repeat domains 1
 860
 0.51
chr20_37435342_37435890 0.32 PPP1R16B
 protein phosphatase 1, regulatory subunit 16B
 1249
 0.47
chr21_46346899_46347050 0.32 ITGB2
 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
 1659
 0.21
chr11_63656035_63656583 0.32 MARK2
 MAP/microtubule affinity-regulating kinase 2
 141
 0.94
chr12_92172716_92172989 0.31 C12orf79
 chromosome 12 open reading frame 79
 357945
 0.01
chr7_3083968_3084119 0.31 CARD11
 caspase recruitment domain family, member 11
 464
 0.86
chr20_61148226_61148454 0.30 C20orf166-AS1
 C20orf166 antisense RNA 1
 378
 0.63
chr19_41260606_41261007 0.30 SNRPA
 small nuclear ribonucleoprotein polypeptide A
 3692
 0.12
chr4_40201867_40202018 0.29 RHOH
 ras homolog family member H
 22
 0.98
chr19_37808857_37809211 0.29 HKR1
 HKR1, GLI-Kruppel zinc finger family member
 93
 0.97
chr12_54891563_54891796 0.29 NCKAP1L
 NCK-associated protein 1-like
 184
 0.93
chr17_76128459_76128696 0.29 TMC6
 transmembrane channel-like 6
 89
 0.94
chr9_100000727_100000985 0.29 CCDC180
 coiled-coil domain containing 180
 77
 0.98
chr1_15249911_15250062 0.29 KAZN
 kazrin, periplakin interacting protein
 640
 0.83
chr3_71478030_71478538 0.29 ENSG00000221264
 .
 112956
 0.06
chr3_196365832_196366436 0.29 NRROS
 negative regulator of reactive oxygen species
 423
 0.51
chr10_8103703_8104121 0.28 GATA3
 GATA binding protein 3
 7143
 0.33
chr13_41187779_41187930 0.28 FOXO1
 forkhead box O1
 52880
 0.14
chr13_41495302_41495814 0.28 SUGT1P3
 SUGT1 pseudogene 3
 289
 0.53
chr2_149634276_149634517 0.28 KIF5C
 kinesin family member 5C
 1577
 0.38
chr6_89790739_89791095 0.27 PNRC1
 proline-rich nuclear receptor coactivator 1
 420
 0.52
chrX_39185008_39185159 0.27 ENSG00000207122
 .
 244545
 0.02
chr20_62271176_62271486 0.27 CTD-3184A7.4
12728
 0.09
chr5_35797219_35797401 0.27 SPEF2
 sperm flagellar 2
 18040
 0.19
chr19_54880943_54881230 0.27 LAIR1
 leukocyte-associated immunoglobulin-like receptor 1
 972
 0.39
chr19_3179462_3180177 0.27 S1PR4
 sphingosine-1-phosphate receptor 4
 1083
 0.38
chr14_22631179_22631341 0.27 ENSG00000238634
 .
 20373
 0.25
chr1_111743477_111743628 0.26 CHI3L2
 chitinase 3-like 2
 159
 0.6
chr3_18466629_18466793 0.26 SATB1
 SATB homeobox 1
 118
 0.97
chr1_155939445_155939596 0.26 ARHGEF2
 Rho/Rac guanine nucleotide exchange factor (GEF) 2
 0
 0.95
chr18_33196454_33196850 0.26 RP11-712P20.2
20787
 0.21
chrX_65294918_65295209 0.26 VSIG4
 V-set and immunoglobulin domain containing 4
 35096
 0.18
chr12_65064432_65064583 0.26 RP11-338E21.3
15708
 0.13
chr12_6570416_6570672 0.26 VAMP1
 vesicle-associated membrane protein 1 (synaptobrevin 1)
 9267
 0.08
chr13_24826013_24826241 0.25 SPATA13
 spermatogenesis associated 13
 271
 0.9
chr1_211503167_211503447 0.25 TRAF5
 TNF receptor-associated factor 5
 3128
 0.31
chr4_90228457_90229530 0.25 GPRIN3
 GPRIN family member 3
 168
 0.97
chr2_203499531_203499682 0.25 FAM117B
 family with sequence similarity 117, member B
 295
 0.94
chr12_54812737_54812923 0.25 ITGA5
 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
 414
 0.6
chr19_51228076_51228227 0.25 CLEC11A
 C-type lectin domain family 11, member A
 1371
 0.27
chr22_33278140_33278291 0.25 TIMP3
 TIMP metallopeptidase inhibitor 3
 80528
 0.1
chr17_54911768_54911997 0.25 DGKE
 diacylglycerol kinase, epsilon 64kDa
 414
 0.59
chr10_135170371_135170656 0.25 FUOM
 fucose mutarotase
 728
 0.41
chr22_24038685_24038889 0.25 RGL4
 ral guanine nucleotide dissociation stimulator-like 4
 116
 0.94
chr17_72755086_72755237 0.25 SLC9A3R1
 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
 2981
 0.14
chr9_131550054_131550269 0.25 TBC1D13
 TBC1 domain family, member 13
 533
 0.64
chr1_9686934_9687157 0.24 PIK3CD
 phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
 24745
 0.14
chr1_110045467_110045747 0.24 AMIGO1
 adhesion molecule with Ig-like domain 1
 6697
 0.11
chr1_12238656_12238807 0.24 TNFRSF1B
 tumor necrosis factor receptor superfamily, member 1B
 11671
 0.15
chr13_103426260_103426509 0.24 TEX30
 testis expressed 30
 223
 0.89
chr2_65356875_65357219 0.24 RAB1A
 RAB1A, member RAS oncogene family
 188
 0.95
chr20_3996304_3996483 0.24 RNF24
 ring finger protein 24
 164
 0.96
chr12_22487067_22487257 0.24 ST8SIA1
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
 31
 0.99
chr15_45008032_45008258 0.24 B2M
 beta-2-microglobulin
 4430
 0.17
chr4_169799366_169799588 0.24 ENSG00000201176
 .
 7029
 0.22
chr5_139493535_139493731 0.23 PURA
 purine-rich element binding protein A
 75
 0.96
chr7_1978940_1979381 0.23 MAD1L1
 MAD1 mitotic arrest deficient-like 1 (yeast)
 1025
 0.64
chr13_99992644_99992897 0.23 ENSG00000207719
 .
 15615
 0.19
chr2_43354715_43354866 0.23 ENSG00000207087
 .
 36158
 0.2
chr10_135089035_135089208 0.23 ADAM8
 ADAM metallopeptidase domain 8
 1233
 0.29
chr20_35575234_35575857 0.23 SAMHD1
 SAM domain and HD domain 1
 4566
 0.25
chr8_94930047_94930344 0.23 PDP1
 pyruvate dehyrogenase phosphatase catalytic subunit 1
 220
 0.92
chr19_17447799_17448161 0.23 GTPBP3
 GTP binding protein 3 (mitochondrial)
 373
 0.68
chrX_153190817_153191535 0.23 ARHGAP4
 Rho GTPase activating protein 4
 522
 0.6
chr2_204191257_204191408 0.23 ABI2
 abl-interactor 2
 1610
 0.37
chr19_17961513_17961726 0.23 JAK3
 Janus kinase 3
 2778
 0.16
chr8_24799151_24799367 0.23 CTD-2168K21.2
14876
 0.17
chr2_136873940_136874440 0.22 CXCR4
 chemokine (C-X-C motif) receptor 4
 377
 0.92
chr9_134139798_134140094 0.22 FAM78A
 family with sequence similarity 78, member A
 5934
 0.19
chr1_6613959_6614285 0.22 NOL9
 nucleolar protein 9
 473
 0.62
chr6_20402144_20402837 0.22 E2F3
 E2F transcription factor 3
 92
 0.96
chr22_21823868_21824019 0.22 PI4KAP2
 phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
 18706
 0.11
chr20_43608188_43608641 0.22 STK4
 serine/threonine kinase 4
 13247
 0.14
chrX_129225814_129226276 0.22 ELF4
 E74-like factor 4 (ets domain transcription factor)
 18291
 0.19
chr21_36901015_36901338 0.22 ENSG00000211590
 .
 191837
 0.03
chr1_27847952_27848103 0.22 RP1-159A19.4
4289
 0.2
chr15_26104297_26104448 0.22 ATP10A
 ATPase, class V, type 10A
 3983
 0.23
chr7_2561879_2562201 0.22 LFNG
 LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
 2544
 0.22
chr20_47411194_47411345 0.22 PREX1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 33151
 0.2
chrX_107070045_107070650 0.22 MID2
 midline 2
 703
 0.7
chr6_135518404_135518725 0.21 MYB-AS1
 MYB antisense RNA 1
 1431
 0.4
chr7_153749645_153749898 0.21 DPP6
 dipeptidyl-peptidase 6
 6
 0.98
chr13_100072782_100072933 0.21 ENSG00000266207
 .
 32866
 0.16
chr17_41712002_41712153 0.21 MEOX1
 mesenchyme homeobox 1
 26854
 0.14
chr13_23754987_23755138 0.21 SGCG
 sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
 29
 0.98
chr17_38720511_38720770 0.21 CCR7
 chemokine (C-C motif) receptor 7
 1071
 0.49
chr5_130617597_130618118 0.21 CDC42SE2
 CDC42 small effector 2
 18064
 0.27
chr6_143178538_143178701 0.21 HIVEP2
 human immunodeficiency virus type I enhancer binding protein 2
 20435
 0.26
chr6_150184570_150184721 0.21 RP11-244K5.8
15
 0.89
chrX_55478600_55478841 0.21 MAGEH1
 melanoma antigen family H, 1
 182
 0.88
chr17_45812120_45812293 0.21 TBX21
 T-box 21
 1596
 0.32
chr5_172111392_172111616 0.21 CTB-79E8.2
13219
 0.15
chr2_5727897_5728048 0.21 AC108025.2
103206
 0.07
chr10_73847731_73848399 0.21 SPOCK2
 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
 21
 0.98
chr22_21058522_21058673 0.20 POM121L4P
 POM121 transmembrane nucleoporin-like 4 pseudogene
 14380
 0.13
chr11_67173386_67173537 0.20 TBC1D10C
 TBC1 domain family, member 10C
 1801
 0.14
chr9_132565902_132566404 0.20 TOR1B
 torsin family 1, member B (torsin B)
 606
 0.67
chr6_159331017_159331168 0.20 ENSG00000223191
 .
 16511
 0.18
chr1_161038546_161039545 0.20 ARHGAP30
 Rho GTPase activating protein 30
 411
 0.65
chr10_53458598_53459393 0.20 CSTF2T
 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
 360
 0.92
chr10_123524520_123524671 0.20 RP11-78A18.2
28777
 0.22
chr16_89427901_89428186 0.20 ANKRD11
 ankyrin repeat domain 11
 32649
 0.1
chr6_37400508_37400927 0.20 CMTR1
 cap methyltransferase 1
 279
 0.92
chrX_134232377_134232653 0.20 FAM127B
 family with sequence similarity 127, member B
 46310
 0.12
chr12_113622602_113622792 0.20 DDX54
 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
 587
 0.4
chr10_102588210_102588406 0.20 ENSG00000222072
 .
 78729
 0.07
chr1_214454566_214454774 0.20 SMYD2
 SET and MYND domain containing 2
 94
 0.98
chr12_21654786_21654996 0.20 GOLT1B
 golgi transport 1B
 142
 0.69
chr3_47029106_47029289 0.20 CCDC12
 coiled-coil domain containing 12
 5725
 0.19
chr20_10153323_10153603 0.20 SNAP25
 synaptosomal-associated protein, 25kDa
 46015
 0.15
chr19_2553269_2553420 0.20 ENSG00000252962
 .
 50205
 0.09
chr1_211501150_211501529 0.20 TRAF5
 TNF receptor-associated factor 5
 1160
 0.57
chr4_148653403_148653650 0.20 ARHGAP10
 Rho GTPase activating protein 10
 312
 0.89
chr9_38424210_38424397 0.20 IGFBPL1
 insulin-like growth factor binding protein-like 1
 141
 0.97
chr22_19879923_19880332 0.20 GNB1L
 guanine nucleotide binding protein (G protein), beta polypeptide 1-like
 37665
 0.1
chr1_64059062_64059382 0.19 PGM1
 phosphoglucomutase 1
 258
 0.92
chr16_28998125_28998276 0.19 LAT
 linker for activation of T cells
 667
 0.47
chr17_75453210_75453403 0.19 SEPT9
 septin 9
 858
 0.54
chr9_125667319_125667538 0.19 RC3H2
 ring finger and CCCH-type domains 2
 66
 0.95
chr10_30818195_30818576 0.19 ENSG00000239744
 .
 26448
 0.21
chr22_18255678_18255932 0.19 BID
 BH3 interacting domain death agonist
 977
 0.55
chr17_36715792_36715943 0.19 SRCIN1
 SRC kinase signaling inhibitor 1
 3793
 0.19
chr19_41833582_41833733 0.19 CCDC97
 coiled-coil domain containing 97
 8019
 0.1
chr8_132916838_132917136 0.19 EFR3A
 EFR3 homolog A (S. cerevisiae)
 631
 0.84
chr14_99655246_99655958 0.19 AL162151.4
30849
 0.2
chr17_38020283_38020945 0.19 IKZF3
 IKAROS family zinc finger 3 (Aiolos)
 173
 0.93
chr14_105955874_105956035 0.19 C14orf80
 chromosome 14 open reading frame 80
 238
 0.86
chr5_140983442_140983851 0.19 AC008781.7
14335
 0.11
chr20_3747782_3747941 0.19 C20orf27
 chromosome 20 open reading frame 27
 514
 0.68
chr6_159483760_159483976 0.19 TAGAP
 T-cell activation RhoGTPase activating protein
 17684
 0.19
chr5_43034344_43034652 0.19 AC025171.1
7179
 0.15
chr2_74214423_74214717 0.19 DGUOK-AS1
 DGUOK antisense RNA 1
 6002
 0.17
chr17_62207148_62207496 0.19 ERN1
 endoplasmic reticulum to nucleus signaling 1
 163
 0.95
chr2_87829980_87830131 0.19 RP11-1399P15.1
52502
 0.16
chr19_3136242_3137376 0.19 GNA15
 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
 618
 0.58
chr12_124873885_124874250 0.19 NCOR2
 nuclear receptor corepressor 2
 697
 0.79
chr11_118087227_118087423 0.19 AMICA1
 adhesion molecule, interacts with CXADR antigen 1
 1719
 0.29
chr7_50728203_50728447 0.19 GRB10
 growth factor receptor-bound protein 10
 33698
 0.21
chr2_127783302_127783743 0.19 ENSG00000238788
 .
 8525
 0.27
chr20_39769733_39769905 0.19 RP1-1J6.2
3176
 0.25
chr19_3275516_3275954 0.18 AC010649.1
27184
 0.14
chr8_146127330_146127682 0.18 ZNF250
 zinc finger protein 250
 47
 0.97
chr14_78174355_78174506 0.18 SLIRP
 SRA stem-loop interacting RNA binding protein
 8
 0.54
chr3_45152218_45152388 0.18 CDCP1
 CUB domain containing protein 1
 35611
 0.16
chr5_134181747_134182027 0.18 C5orf24
 chromosome 5 open reading frame 24
 43
 0.97
chr1_233085968_233086196 0.18 NTPCR
 nucleoside-triphosphatase, cancer-related
 288
 0.94
chr8_86132724_86133084 0.18 C8orf59
 chromosome 8 open reading frame 59
 254
 0.88
chr18_60383353_60383643 0.18 PHLPP1
 PH domain and leucine rich repeat protein phosphatase 1
 815
 0.66
chr7_150180608_150181504 0.18 GIMAP7
 GTPase, IMAP family member 7
 30862
 0.13
chr16_71930385_71930591 0.18 IST1
 increased sodium tolerance 1 homolog (yeast)
 996
 0.42
chr10_32667341_32667675 0.18 EPC1
 enhancer of polycomb homolog 1 (Drosophila)
 218
 0.91
chr12_4377755_4378334 0.18 CCND2
 cyclin D2
 4894
 0.19
chr12_122230356_122230788 0.18 RHOF
 ras homolog family member F (in filopodia)
 694
 0.64
chr6_33244320_33244875 0.18 B3GALT4
 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
 320
 0.73
chr19_4370207_4370410 0.18 AC007292.6
6522
 0.08
chr17_39781410_39781561 0.18 KRT17
 keratin 17
 391
 0.74
chr8_145447065_145447230 0.18 FAM203B
 family with sequence similarity 203, member B
 8277
 0.11
chr1_6418667_6418818 0.18 ACOT7
 acyl-CoA thioesterase 7
 662
 0.65
chr17_30335047_30335869 0.18 LRRC37B
 leucine rich repeat containing 37B
 451
 0.82
chr19_39368685_39368907 0.18 RINL
 Ras and Rab interactor-like
 98
 0.92
chr16_89626287_89626438 0.18 RPL13
 ribosomal protein L13
 703
 0.46
chr20_56193926_56194226 0.18 ZBP1
 Z-DNA binding protein 1
 1374
 0.49
chr10_29970067_29970318 0.18 ENSG00000222092
 .
 30652
 0.18
chr20_49547938_49548164 0.18 ADNP
 activity-dependent neuroprotector homeobox
 93
 0.87
chr7_5436621_5436873 0.18 TNRC18
 trinucleotide repeat containing 18
 9087
 0.16
chr20_1666477_1666686 0.18 ENSG00000242348
 .
 19575
 0.16
chr19_3179098_3179452 0.18 S1PR4
 sphingosine-1-phosphate receptor 4
 539
 0.66
chr8_145806326_145806590 0.18 CTD-2517M22.9
2966
 0.14
chr12_58176565_58177298 0.18 TSFM
 Ts translation elongation factor, mitochondrial
 330
 0.69
chr3_47205224_47205443 0.18 SETD2
 SET domain containing 2
 124
 0.89
chr12_120427127_120427447 0.17 CCDC64
 coiled-coil domain containing 64
 386
 0.88
chr4_57843034_57843451 0.17 POLR2B
 polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
 646
 0.6
chr6_24934972_24935145 0.17 FAM65B
 family with sequence similarity 65, member B
 1130
 0.57
chr9_37592643_37592824 0.17 TOMM5
 translocase of outer mitochondrial membrane 5 homolog (yeast)
 94
 0.96
chr1_61063097_61063248 0.17 NFIA
 nuclear factor I/A
 267759
 0.02
chr12_113495521_113495672 0.17 DTX1
 deltex homolog 1 (Drosophila)
 101
 0.97
chr11_93276609_93276770 0.17 SMCO4
 single-pass membrane protein with coiled-coil domains 4
 15
 0.98
chr13_19183550_19183860 0.17 ENSG00000223024
 .
 259726
 0.02
chr6_13615615_13616144 0.17 NOL7
 nucleolar protein 7, 27kDa
 100
 0.86
chr11_18127258_18127617 0.17 SAAL1
 serum amyloid A-like 1
 129
 0.95

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000089 mitotic metaphase(GO:0000089)
0.1 0.4 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.7 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.2 GO:0060049 regulation of protein glycosylation(GO:0060049)
0.1 0.4 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.2 GO:0043373 T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1 0.2 GO:0044268 multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.1 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.1 0.1 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.2 GO:0019348 polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1 0.2 GO:0072216 positive regulation of metanephros development(GO:0072216)
0.1 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.0 0.2 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426)
0.0 0.2 GO:0002313 mature B cell differentiation involved in immune response(GO:0002313)
0.0 0.1 GO:0007207 phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0 0.2 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.0 GO:0031062 positive regulation of histone methylation(GO:0031062)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.3 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.5 GO:0045061 thymic T cell selection(GO:0045061)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.1 GO:0009191 nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0032803 regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0 0.7 GO:0030101 natural killer cell activation(GO:0030101)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.1 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 0.0 GO:0032353 negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.3 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.1 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0 0.1 GO:0060897 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.0 GO:0030223 neutrophil differentiation(GO:0030223)
0.0 0.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0 0.0 GO:0070230 positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0 0.1 GO:0015864 pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0000090 mitotic anaphase(GO:0000090)
0.0 0.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0006378 mRNA polyadenylation(GO:0006378)
0.0 0.2 GO:0019059 obsolete initiation of viral infection(GO:0019059)
0.0 0.2 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.2 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0000085 mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0 0.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.3 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.1 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.2 GO:0051000 positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0 0.1 GO:0007090 obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0 0.1 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.1 GO:0031946 regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0 0.0 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.0 GO:0006922 obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0 0.1 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:0009209 GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0 0.1 GO:0032717 negative regulation of interleukin-8 production(GO:0032717)
0.0 0.1 GO:0070670 response to interleukin-4(GO:0070670)
0.0 0.2 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.1 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0021561 facial nerve development(GO:0021561)
0.0 0.1 GO:0008089 anterograde axonal transport(GO:0008089)
0.0 0.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0045655 regulation of monocyte differentiation(GO:0045655)
0.0 0.1 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.4 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0 0.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.0 0.1 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.2 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0002820 negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0 0.0 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0002679 respiratory burst involved in defense response(GO:0002679)
0.0 0.1 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0002717 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.1 GO:0008653 lipopolysaccharide metabolic process(GO:0008653)
0.0 0.4 GO:0008633 obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0 0.1 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0000959 mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0016601 Rac protein signal transduction(GO:0016601)
0.0 0.2 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0031060 regulation of histone methylation(GO:0031060) negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.0 GO:0034139 regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0 0.0 GO:0046132 pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0 0.0 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.0 0.1 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0 0.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.4 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0006400 tRNA modification(GO:0006400)
0.0 0.2 GO:0000305 response to oxygen radical(GO:0000305)
0.0 0.0 GO:0032069 regulation of nuclease activity(GO:0032069)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549)
0.0 0.0 GO:0009215 purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0 0.0 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056)
0.0 0.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.0 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0034311 diol metabolic process(GO:0034311)
0.0 0.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.0 0.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.0 GO:0001705 ectoderm formation(GO:0001705)
0.0 0.0 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.0 GO:0000470 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.0 GO:0045007 depurination(GO:0045007)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.0 GO:0010834 obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0 0.3 GO:0006672 ceramide metabolic process(GO:0006672)
0.0 0.1 GO:0000132 establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:1901797 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0 0.0 GO:0022614 membrane to membrane docking(GO:0022614)
0.0 0.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.0 0.0 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.0 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.1 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851)
0.0 0.3 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.0 GO:0033688 regulation of osteoblast proliferation(GO:0033688)
0.0 0.2 GO:0061641 DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.0 GO:0006154 adenosine catabolic process(GO:0006154)
0.0 0.4 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.0 GO:0002085 inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0046519 sphingoid metabolic process(GO:0046519)
0.0 0.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.3 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.0 0.1 GO:0061001 dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0 0.0 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.0 0.0 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.1 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0001510 RNA methylation(GO:0001510)
0.0 0.0 GO:0018101 protein citrullination(GO:0018101)
0.0 0.2 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.0 GO:0048261 negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0 0.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 0.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.2 GO:0042584 chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.3 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.0 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0005954 calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0 0.1 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.1 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.1 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0016235 aggresome(GO:0016235)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.2 GO:0030530 obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0043230 extracellular organelle(GO:0043230)
0.0 0.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.0 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0000109 nucleotide-excision repair complex(GO:0000109)
0.0 0.0 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.0 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0001950 obsolete plasma membrane enriched fraction(GO:0001950)
0.0 0.0 GO:0070545 PeBoW complex(GO:0070545)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.0 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.2 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0042153 obsolete RPTP-like protein binding(GO:0042153)
0.0 0.2 GO:0034452 dynactin binding(GO:0034452)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.1 GO:0000739 obsolete DNA strand annealing activity(GO:0000739)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.1 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0004568 chitinase activity(GO:0004568)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.2 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0050897 cobalt ion binding(GO:0050897)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.0 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0001619 obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.1 GO:0042156 obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.0 GO:0000987 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 0.1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.0 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.0 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0070402 NADPH binding(GO:0070402)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.0 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 0.1 GO:0051766 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0 0.3 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0016944 obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0 0.1 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.0 GO:0016972 thiol oxidase activity(GO:0016972)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.0 GO:0043734 DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0008159 obsolete positive transcription elongation factor activity(GO:0008159)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0005123 death receptor binding(GO:0005123)
0.0 0.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.0 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0019864 IgG binding(GO:0019864)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.0 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.0 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.0 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0015925 galactosidase activity(GO:0015925)
0.0 0.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.1 GO:0004437 obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0 0.0 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.0 GO:0005346 purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.0 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.0 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.0 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0 0.6 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.1 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.2 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.0 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.7 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.0 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0 0.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.0 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.1 REACTOME UNFOLDED PROTEIN RESPONSE Genes involved in Unfolded Protein Response
0.0 0.0 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.1 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.9 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 0.1 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)