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ENCODE: H3K4me3 ChIP-Seq of primary human cells

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for MAFA

Z-value: 1.01

Motif logo

Transcription factors associated with MAFA

Gene Symbol	Gene ID	Gene Info
MAFA Ensembl NCBI GeneCards UniProt	ENSG00000182759.3	MAFA

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
MAFA	chr8_144510266_144510417	2235	0.183325	0.77	1.4e-02	Click!
MAFA	chr8_144543935_144544113	31448	0.084746	0.76	1.8e-02	Click!
MAFA	chr8_144544411_144544712	31985	0.083952	0.72	3.0e-02	Click!
MAFA	chr8_144510497_144510807	1924	0.207447	0.71	3.4e-02	Click!
MAFA	chr8_144544755_144544972	32287	0.083504	0.71	3.4e-02	Click!

Activity of the MAFA motif across conditions

Conditions sorted by the z-value of the MAFA motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_40684769_40685057	0.56	PTGER4	prostaglandin E receptor 4 (subtype EP4)	5313	0.23
chr14_100533458_100533776	0.53	EVL	Enah/Vasp-like	843	0.55
chr16_27414444_27414647	0.48	IL21R	interleukin 21 receptor	122	0.97
chrY_7207933_7208104	0.46	ENSG00000251996	.	1554	0.4
chr7_150148386_150148563	0.46	GIMAP8	GTPase, IMAP family member 8	756	0.63
chr10_6621928_6622130	0.39	PRKCQ	protein kinase C, theta	172	0.98
chr14_69095479_69095684	0.39	CTD-2325P2.4		419	0.89
chr16_87799045_87799225	0.39	KLHDC4	kelch domain containing 4	370	0.86
chr16_3628507_3629057	0.39	NLRC3	NLR family, CARD domain containing 3	1381	0.35
chr3_81545471_81545622	0.38	ENSG00000222389	.	13081	0.32
chr13_99222825_99223522	0.37	STK24	serine/threonine kinase 24	5944	0.22
chr16_89788020_89788196	0.36	ZNF276	zinc finger protein 276	156	0.84
chr11_16946573_16946796	0.35	PLEKHA7	pleckstrin homology domain containing, family A member 7	43779	0.12
chr1_145440326_145440711	0.35	TXNIP	thioredoxin interacting protein	1212	0.33
chr19_6501621_6501878	0.34	TUBB4A	tubulin, beta 4A class IVa	49	0.95
chrX_123481094_123481375	0.34	SH2D1A	SH2 domain containing 1A	795	0.78
chr17_76123138_76123289	0.34	TMC6	transmembrane channel-like 6	112	0.94
chr8_134080772_134080923	0.34	SLA	Src-like-adaptor	8244	0.25
chr19_49931722_49931873	0.33	GFY	golgi-associated, olfactory signaling regulator	4791	0.07
chr1_36272671_36272822	0.32	AGO4	argonaute RISC catalytic component 4	1027	0.53
chr9_503761_503951	0.32	KANK1	KN motif and ankyrin repeat domains 1	860	0.51
chr20_37435342_37435890	0.32	PPP1R16B	protein phosphatase 1, regulatory subunit 16B	1249	0.47
chr21_46346899_46347050	0.32	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	1659	0.21
chr11_63656035_63656583	0.32	MARK2	MAP/microtubule affinity-regulating kinase 2	141	0.94
chr12_92172716_92172989	0.31	C12orf79	chromosome 12 open reading frame 79	357945	0.01
chr7_3083968_3084119	0.31	CARD11	caspase recruitment domain family, member 11	464	0.86
chr20_61148226_61148454	0.30	C20orf166-AS1	C20orf166 antisense RNA 1	378	0.63
chr19_41260606_41261007	0.30	SNRPA	small nuclear ribonucleoprotein polypeptide A	3692	0.12
chr4_40201867_40202018	0.29	RHOH	ras homolog family member H	22	0.98
chr19_37808857_37809211	0.29	HKR1	HKR1, GLI-Kruppel zinc finger family member	93	0.97
chr12_54891563_54891796	0.29	NCKAP1L	NCK-associated protein 1-like	184	0.93
chr17_76128459_76128696	0.29	TMC6	transmembrane channel-like 6	89	0.94
chr9_100000727_100000985	0.29	CCDC180	coiled-coil domain containing 180	77	0.98
chr1_15249911_15250062	0.29	KAZN	kazrin, periplakin interacting protein	640	0.83
chr3_71478030_71478538	0.29	ENSG00000221264	.	112956	0.06
chr3_196365832_196366436	0.29	NRROS	negative regulator of reactive oxygen species	423	0.51
chr10_8103703_8104121	0.28	GATA3	GATA binding protein 3	7143	0.33
chr13_41187779_41187930	0.28	FOXO1	forkhead box O1	52880	0.14
chr13_41495302_41495814	0.28	SUGT1P3	SUGT1 pseudogene 3	289	0.53
chr2_149634276_149634517	0.28	KIF5C	kinesin family member 5C	1577	0.38
chr6_89790739_89791095	0.27	PNRC1	proline-rich nuclear receptor coactivator 1	420	0.52
chrX_39185008_39185159	0.27	ENSG00000207122	.	244545	0.02
chr20_62271176_62271486	0.27	CTD-3184A7.4		12728	0.09
chr5_35797219_35797401	0.27	SPEF2	sperm flagellar 2	18040	0.19
chr19_54880943_54881230	0.27	LAIR1	leukocyte-associated immunoglobulin-like receptor 1	972	0.39
chr19_3179462_3180177	0.27	S1PR4	sphingosine-1-phosphate receptor 4	1083	0.38
chr14_22631179_22631341	0.27	ENSG00000238634	.	20373	0.25
chr1_111743477_111743628	0.26	CHI3L2	chitinase 3-like 2	159	0.6
chr3_18466629_18466793	0.26	SATB1	SATB homeobox 1	118	0.97
chr1_155939445_155939596	0.26	ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0	0.95
chr18_33196454_33196850	0.26	RP11-712P20.2		20787	0.21
chrX_65294918_65295209	0.26	VSIG4	V-set and immunoglobulin domain containing 4	35096	0.18
chr12_65064432_65064583	0.26	RP11-338E21.3		15708	0.13
chr12_6570416_6570672	0.26	VAMP1	vesicle-associated membrane protein 1 (synaptobrevin 1)	9267	0.08
chr13_24826013_24826241	0.25	SPATA13	spermatogenesis associated 13	271	0.9
chr1_211503167_211503447	0.25	TRAF5	TNF receptor-associated factor 5	3128	0.31
chr4_90228457_90229530	0.25	GPRIN3	GPRIN family member 3	168	0.97
chr2_203499531_203499682	0.25	FAM117B	family with sequence similarity 117, member B	295	0.94
chr12_54812737_54812923	0.25	ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	414	0.6
chr19_51228076_51228227	0.25	CLEC11A	C-type lectin domain family 11, member A	1371	0.27
chr22_33278140_33278291	0.25	TIMP3	TIMP metallopeptidase inhibitor 3	80528	0.1
chr17_54911768_54911997	0.25	DGKE	diacylglycerol kinase, epsilon 64kDa	414	0.59
chr10_135170371_135170656	0.25	FUOM	fucose mutarotase	728	0.41
chr22_24038685_24038889	0.25	RGL4	ral guanine nucleotide dissociation stimulator-like 4	116	0.94
chr17_72755086_72755237	0.25	SLC9A3R1	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1	2981	0.14
chr9_131550054_131550269	0.25	TBC1D13	TBC1 domain family, member 13	533	0.64
chr1_9686934_9687157	0.24	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	24745	0.14
chr1_110045467_110045747	0.24	AMIGO1	adhesion molecule with Ig-like domain 1	6697	0.11
chr1_12238656_12238807	0.24	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	11671	0.15
chr13_103426260_103426509	0.24	TEX30	testis expressed 30	223	0.89
chr2_65356875_65357219	0.24	RAB1A	RAB1A, member RAS oncogene family	188	0.95
chr20_3996304_3996483	0.24	RNF24	ring finger protein 24	164	0.96
chr12_22487067_22487257	0.24	ST8SIA1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	31	0.99
chr15_45008032_45008258	0.24	B2M	beta-2-microglobulin	4430	0.17
chr4_169799366_169799588	0.24	ENSG00000201176	.	7029	0.22
chr5_139493535_139493731	0.23	PURA	purine-rich element binding protein A	75	0.96
chr7_1978940_1979381	0.23	MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	1025	0.64
chr13_99992644_99992897	0.23	ENSG00000207719	.	15615	0.19
chr2_43354715_43354866	0.23	ENSG00000207087	.	36158	0.2
chr10_135089035_135089208	0.23	ADAM8	ADAM metallopeptidase domain 8	1233	0.29
chr20_35575234_35575857	0.23	SAMHD1	SAM domain and HD domain 1	4566	0.25
chr8_94930047_94930344	0.23	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1	220	0.92
chr19_17447799_17448161	0.23	GTPBP3	GTP binding protein 3 (mitochondrial)	373	0.68
chrX_153190817_153191535	0.23	ARHGAP4	Rho GTPase activating protein 4	522	0.6
chr2_204191257_204191408	0.23	ABI2	abl-interactor 2	1610	0.37
chr19_17961513_17961726	0.23	JAK3	Janus kinase 3	2778	0.16
chr8_24799151_24799367	0.23	CTD-2168K21.2		14876	0.17
chr2_136873940_136874440	0.22	CXCR4	chemokine (C-X-C motif) receptor 4	377	0.92
chr9_134139798_134140094	0.22	FAM78A	family with sequence similarity 78, member A	5934	0.19
chr1_6613959_6614285	0.22	NOL9	nucleolar protein 9	473	0.62
chr6_20402144_20402837	0.22	E2F3	E2F transcription factor 3	92	0.96
chr22_21823868_21824019	0.22	PI4KAP2	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2	18706	0.11
chr20_43608188_43608641	0.22	STK4	serine/threonine kinase 4	13247	0.14
chrX_129225814_129226276	0.22	ELF4	E74-like factor 4 (ets domain transcription factor)	18291	0.19
chr21_36901015_36901338	0.22	ENSG00000211590	.	191837	0.03
chr1_27847952_27848103	0.22	RP1-159A19.4		4289	0.2
chr15_26104297_26104448	0.22	ATP10A	ATPase, class V, type 10A	3983	0.23
chr7_2561879_2562201	0.22	LFNG	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	2544	0.22
chr20_47411194_47411345	0.22	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	33151	0.2
chrX_107070045_107070650	0.22	MID2	midline 2	703	0.7
chr6_135518404_135518725	0.21	MYB-AS1	MYB antisense RNA 1	1431	0.4
chr7_153749645_153749898	0.21	DPP6	dipeptidyl-peptidase 6	6	0.98
chr13_100072782_100072933	0.21	ENSG00000266207	.	32866	0.16
chr17_41712002_41712153	0.21	MEOX1	mesenchyme homeobox 1	26854	0.14
chr13_23754987_23755138	0.21	SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	29	0.98
chr17_38720511_38720770	0.21	CCR7	chemokine (C-C motif) receptor 7	1071	0.49
chr5_130617597_130618118	0.21	CDC42SE2	CDC42 small effector 2	18064	0.27
chr6_143178538_143178701	0.21	HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	20435	0.26
chr6_150184570_150184721	0.21	RP11-244K5.8		15	0.89
chrX_55478600_55478841	0.21	MAGEH1	melanoma antigen family H, 1	182	0.88
chr17_45812120_45812293	0.21	TBX21	T-box 21	1596	0.32
chr5_172111392_172111616	0.21	CTB-79E8.2		13219	0.15
chr2_5727897_5728048	0.21	AC108025.2		103206	0.07
chr10_73847731_73848399	0.21	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2	21	0.98
chr22_21058522_21058673	0.20	POM121L4P	POM121 transmembrane nucleoporin-like 4 pseudogene	14380	0.13
chr11_67173386_67173537	0.20	TBC1D10C	TBC1 domain family, member 10C	1801	0.14
chr9_132565902_132566404	0.20	TOR1B	torsin family 1, member B (torsin B)	606	0.67
chr6_159331017_159331168	0.20	ENSG00000223191	.	16511	0.18
chr1_161038546_161039545	0.20	ARHGAP30	Rho GTPase activating protein 30	411	0.65
chr10_53458598_53459393	0.20	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant	360	0.92
chr10_123524520_123524671	0.20	RP11-78A18.2		28777	0.22
chr16_89427901_89428186	0.20	ANKRD11	ankyrin repeat domain 11	32649	0.1
chr6_37400508_37400927	0.20	CMTR1	cap methyltransferase 1	279	0.92
chrX_134232377_134232653	0.20	FAM127B	family with sequence similarity 127, member B	46310	0.12
chr12_113622602_113622792	0.20	DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	587	0.4
chr10_102588210_102588406	0.20	ENSG00000222072	.	78729	0.07
chr1_214454566_214454774	0.20	SMYD2	SET and MYND domain containing 2	94	0.98
chr12_21654786_21654996	0.20	GOLT1B	golgi transport 1B	142	0.69
chr3_47029106_47029289	0.20	CCDC12	coiled-coil domain containing 12	5725	0.19
chr20_10153323_10153603	0.20	SNAP25	synaptosomal-associated protein, 25kDa	46015	0.15
chr19_2553269_2553420	0.20	ENSG00000252962	.	50205	0.09
chr1_211501150_211501529	0.20	TRAF5	TNF receptor-associated factor 5	1160	0.57
chr4_148653403_148653650	0.20	ARHGAP10	Rho GTPase activating protein 10	312	0.89
chr9_38424210_38424397	0.20	IGFBPL1	insulin-like growth factor binding protein-like 1	141	0.97
chr22_19879923_19880332	0.20	GNB1L	guanine nucleotide binding protein (G protein), beta polypeptide 1-like	37665	0.1
chr1_64059062_64059382	0.19	PGM1	phosphoglucomutase 1	258	0.92
chr16_28998125_28998276	0.19	LAT	linker for activation of T cells	667	0.47
chr17_75453210_75453403	0.19	SEPT9	septin 9	858	0.54
chr9_125667319_125667538	0.19	RC3H2	ring finger and CCCH-type domains 2	66	0.95
chr10_30818195_30818576	0.19	ENSG00000239744	.	26448	0.21
chr22_18255678_18255932	0.19	BID	BH3 interacting domain death agonist	977	0.55
chr17_36715792_36715943	0.19	SRCIN1	SRC kinase signaling inhibitor 1	3793	0.19
chr19_41833582_41833733	0.19	CCDC97	coiled-coil domain containing 97	8019	0.1
chr8_132916838_132917136	0.19	EFR3A	EFR3 homolog A (S. cerevisiae)	631	0.84
chr14_99655246_99655958	0.19	AL162151.4		30849	0.2
chr17_38020283_38020945	0.19	IKZF3	IKAROS family zinc finger 3 (Aiolos)	173	0.93
chr14_105955874_105956035	0.19	C14orf80	chromosome 14 open reading frame 80	238	0.86
chr5_140983442_140983851	0.19	AC008781.7		14335	0.11
chr20_3747782_3747941	0.19	C20orf27	chromosome 20 open reading frame 27	514	0.68
chr6_159483760_159483976	0.19	TAGAP	T-cell activation RhoGTPase activating protein	17684	0.19
chr5_43034344_43034652	0.19	AC025171.1		7179	0.15
chr2_74214423_74214717	0.19	DGUOK-AS1	DGUOK antisense RNA 1	6002	0.17
chr17_62207148_62207496	0.19	ERN1	endoplasmic reticulum to nucleus signaling 1	163	0.95
chr2_87829980_87830131	0.19	RP11-1399P15.1		52502	0.16
chr19_3136242_3137376	0.19	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	618	0.58
chr12_124873885_124874250	0.19	NCOR2	nuclear receptor corepressor 2	697	0.79
chr11_118087227_118087423	0.19	AMICA1	adhesion molecule, interacts with CXADR antigen 1	1719	0.29
chr7_50728203_50728447	0.19	GRB10	growth factor receptor-bound protein 10	33698	0.21
chr2_127783302_127783743	0.19	ENSG00000238788	.	8525	0.27
chr20_39769733_39769905	0.19	RP1-1J6.2		3176	0.25
chr19_3275516_3275954	0.18	AC010649.1		27184	0.14
chr8_146127330_146127682	0.18	ZNF250	zinc finger protein 250	47	0.97
chr14_78174355_78174506	0.18	SLIRP	SRA stem-loop interacting RNA binding protein	8	0.54
chr3_45152218_45152388	0.18	CDCP1	CUB domain containing protein 1	35611	0.16
chr5_134181747_134182027	0.18	C5orf24	chromosome 5 open reading frame 24	43	0.97
chr1_233085968_233086196	0.18	NTPCR	nucleoside-triphosphatase, cancer-related	288	0.94
chr8_86132724_86133084	0.18	C8orf59	chromosome 8 open reading frame 59	254	0.88
chr18_60383353_60383643	0.18	PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	815	0.66
chr7_150180608_150181504	0.18	GIMAP7	GTPase, IMAP family member 7	30862	0.13
chr16_71930385_71930591	0.18	IST1	increased sodium tolerance 1 homolog (yeast)	996	0.42
chr10_32667341_32667675	0.18	EPC1	enhancer of polycomb homolog 1 (Drosophila)	218	0.91
chr12_4377755_4378334	0.18	CCND2	cyclin D2	4894	0.19
chr12_122230356_122230788	0.18	RHOF	ras homolog family member F (in filopodia)	694	0.64
chr6_33244320_33244875	0.18	B3GALT4	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4	320	0.73
chr19_4370207_4370410	0.18	AC007292.6		6522	0.08
chr17_39781410_39781561	0.18	KRT17	keratin 17	391	0.74
chr8_145447065_145447230	0.18	FAM203B	family with sequence similarity 203, member B	8277	0.11
chr1_6418667_6418818	0.18	ACOT7	acyl-CoA thioesterase 7	662	0.65
chr17_30335047_30335869	0.18	LRRC37B	leucine rich repeat containing 37B	451	0.82
chr19_39368685_39368907	0.18	RINL	Ras and Rab interactor-like	98	0.92
chr16_89626287_89626438	0.18	RPL13	ribosomal protein L13	703	0.46
chr20_56193926_56194226	0.18	ZBP1	Z-DNA binding protein 1	1374	0.49
chr10_29970067_29970318	0.18	ENSG00000222092	.	30652	0.18
chr20_49547938_49548164	0.18	ADNP	activity-dependent neuroprotector homeobox	93	0.87
chr7_5436621_5436873	0.18	TNRC18	trinucleotide repeat containing 18	9087	0.16
chr20_1666477_1666686	0.18	ENSG00000242348	.	19575	0.16
chr19_3179098_3179452	0.18	S1PR4	sphingosine-1-phosphate receptor 4	539	0.66
chr8_145806326_145806590	0.18	CTD-2517M22.9		2966	0.14
chr12_58176565_58177298	0.18	TSFM	Ts translation elongation factor, mitochondrial	330	0.69
chr3_47205224_47205443	0.18	SETD2	SET domain containing 2	124	0.89
chr12_120427127_120427447	0.17	CCDC64	coiled-coil domain containing 64	386	0.88
chr4_57843034_57843451	0.17	POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	646	0.6
chr6_24934972_24935145	0.17	FAM65B	family with sequence similarity 65, member B	1130	0.57
chr9_37592643_37592824	0.17	TOMM5	translocase of outer mitochondrial membrane 5 homolog (yeast)	94	0.96
chr1_61063097_61063248	0.17	NFIA	nuclear factor I/A	267759	0.02
chr12_113495521_113495672	0.17	DTX1	deltex homolog 1 (Drosophila)	101	0.97
chr11_93276609_93276770	0.17	SMCO4	single-pass membrane protein with coiled-coil domains 4	15	0.98
chr13_19183550_19183860	0.17	ENSG00000223024	.	259726	0.02
chr6_13615615_13616144	0.17	NOL7	nucleolar protein 7, 27kDa	100	0.86
chr11_18127258_18127617	0.17	SAAL1	serum amyloid A-like 1	129	0.95

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of MAFA

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0000089	mitotic metaphase(GO:0000089)
0.1	0.4	GO:0036037	CD8-positive, alpha-beta T cell activation(GO:0036037) CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1	0.7	GO:0051489	regulation of filopodium assembly(GO:0051489)
0.1	0.2	GO:0003032	detection of oxygen(GO:0003032)
0.1	0.2	GO:0060049	regulation of protein glycosylation(GO:0060049)
0.1	0.4	GO:0010452	histone H3-K36 methylation(GO:0010452)
0.1	0.2	GO:0043373	T-helper cell lineage commitment(GO:0002295) alpha-beta T cell lineage commitment(GO:0002363) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373) memory T cell differentiation(GO:0043379) regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382) T-helper 17 type immune response(GO:0072538) T-helper 17 cell differentiation(GO:0072539) T-helper 17 cell lineage commitment(GO:0072540) regulation of T-helper 17 type immune response(GO:2000316) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 17 cell differentiation(GO:2000319) positive regulation of T-helper 17 cell differentiation(GO:2000321) regulation of T-helper 17 cell lineage commitment(GO:2000328) positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.1	0.2	GO:0044268	multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266) multicellular organismal protein metabolic process(GO:0044268)
0.1	0.2	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1	0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.1	0.1	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
0.1	0.2	GO:0019348	polyprenol metabolic process(GO:0016093) dolichol metabolic process(GO:0019348)
0.1	0.2	GO:0072216	positive regulation of metanephros development(GO:0072216)
0.1	0.2	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.2	GO:0042668	auditory receptor cell fate determination(GO:0042668)
0.0	0.2	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0060426	lung vasculature development(GO:0060426)
0.0	0.2	GO:0002313	mature B cell differentiation involved in immune response(GO:0002313)
0.0	0.1	GO:0007207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.2	GO:0032075	positive regulation of nuclease activity(GO:0032075)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0031062	positive regulation of histone methylation(GO:0031062)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.3	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.5	GO:0045061	thymic T cell selection(GO:0045061)
0.0	0.2	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0009191	nucleoside diphosphate catabolic process(GO:0009134) ribonucleoside diphosphate catabolic process(GO:0009191)
0.0	0.1	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:2000114	regulation of establishment of cell polarity(GO:2000114)
0.0	0.1	GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803) regulation of receptor catabolic process(GO:2000644)
0.0	0.7	GO:0030101	natural killer cell activation(GO:0030101)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.2	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0	0.1	GO:0050774	negative regulation of dendrite morphogenesis(GO:0050774)
0.0	0.1	GO:0006434	seryl-tRNA aminoacylation(GO:0006434)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.3	GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0	0.1	GO:0071364	cellular response to epidermal growth factor stimulus(GO:0071364)
0.0	0.0	GO:0032353	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0006667	sphinganine metabolic process(GO:0006667)
0.0	0.2	GO:0006030	chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.3	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0045591	positive regulation of regulatory T cell differentiation(GO:0045591)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.0	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.1	GO:0019372	lipoxygenase pathway(GO:0019372)
0.0	0.1	GO:0061756	leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.0	0.1	GO:0060897	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.0	GO:0030223	neutrophil differentiation(GO:0030223)
0.0	0.1	GO:0035020	regulation of Rac protein signal transduction(GO:0035020)
0.0	0.1	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.0	0.1	GO:0009136	ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
0.0	0.0	GO:0070230	positive regulation of lymphocyte apoptotic process(GO:0070230)
0.0	0.1	GO:0015864	pyrimidine nucleoside transport(GO:0015864)
0.0	0.0	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.0	GO:0072501	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.0	0.2	GO:0000090	mitotic anaphase(GO:0000090)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.1	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.3	GO:0006378	mRNA polyadenylation(GO:0006378)
0.0	0.2	GO:0019059	obsolete initiation of viral infection(GO:0019059)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.2	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.2	GO:0000085	mitotic G2 phase(GO:0000085) G2 phase(GO:0051319)
0.0	0.1	GO:0050765	negative regulation of phagocytosis(GO:0050765)
0.0	0.3	GO:0006541	glutamine metabolic process(GO:0006541)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.2	GO:0051000	positive regulation of nitric-oxide synthase activity(GO:0051000)
0.0	0.1	GO:0007090	obsolete regulation of S phase of mitotic cell cycle(GO:0007090)
0.0	0.1	GO:0046502	uroporphyrinogen III metabolic process(GO:0046502)
0.0	0.1	GO:0031946	regulation of glucocorticoid biosynthetic process(GO:0031946)
0.0	0.0	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0006922	obsolete cleavage of lamin involved in execution phase of apoptosis(GO:0006922)
0.0	0.1	GO:0021819	layer formation in cerebral cortex(GO:0021819)
0.0	0.1	GO:0009209	GTP biosynthetic process(GO:0006183) UTP biosynthetic process(GO:0006228) CTP biosynthetic process(GO:0006241) pyrimidine ribonucleoside triphosphate metabolic process(GO:0009208) pyrimidine ribonucleoside triphosphate biosynthetic process(GO:0009209) CTP metabolic process(GO:0046036) UTP metabolic process(GO:0046051)
0.0	0.1	GO:0032717	negative regulation of interleukin-8 production(GO:0032717)
0.0	0.1	GO:0070670	response to interleukin-4(GO:0070670)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	0.1	GO:0007386	compartment pattern specification(GO:0007386)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0021561	facial nerve development(GO:0021561)
0.0	0.1	GO:0008089	anterograde axonal transport(GO:0008089)
0.0	0.1	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	0.1	GO:0034379	very-low-density lipoprotein particle assembly(GO:0034379)
0.0	0.1	GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0	0.1	GO:0045655	regulation of monocyte differentiation(GO:0045655)
0.0	0.1	GO:0045672	positive regulation of osteoclast differentiation(GO:0045672)
0.0	0.4	GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.0	0.0	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.1	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.2	GO:0032784	regulation of DNA-templated transcription, elongation(GO:0032784)
0.0	0.1	GO:0002820	negative regulation of adaptive immune response(GO:0002820) negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002823)
0.0	0.0	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.2	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:0002679	respiratory burst involved in defense response(GO:0002679)
0.0	0.1	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.0	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0002717	positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0	0.1	GO:0008653	lipopolysaccharide metabolic process(GO:0008653)
0.0	0.4	GO:0008633	obsolete activation of pro-apoptotic gene products(GO:0008633)
0.0	0.1	GO:0061077	chaperone-mediated protein folding(GO:0061077)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0000959	mitochondrial RNA metabolic process(GO:0000959) transcription from mitochondrial promoter(GO:0006390)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.2	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.0	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.1	GO:0016601	Rac protein signal transduction(GO:0016601)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.3	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0031060	regulation of histone methylation(GO:0031060) negative regulation of histone methylation(GO:0031061)
0.0	0.1	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.2	GO:0007076	mitotic chromosome condensation(GO:0007076)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139)
0.0	0.0	GO:0046132	pyrimidine ribonucleoside biosynthetic process(GO:0046132)
0.0	0.0	GO:0007007	inner mitochondrial membrane organization(GO:0007007)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) positive regulation of sprouting angiogenesis(GO:1903672)
0.0	0.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.1	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.4	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.3	GO:0006400	tRNA modification(GO:0006400)
0.0	0.2	GO:0000305	response to oxygen radical(GO:0000305)
0.0	0.0	GO:0032069	regulation of nuclease activity(GO:0032069)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549)
0.0	0.0	GO:0009215	purine deoxyribonucleoside triphosphate metabolic process(GO:0009215)
0.0	0.0	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.2	GO:0015936	coenzyme A metabolic process(GO:0015936)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0042501	serine phosphorylation of STAT protein(GO:0042501)
0.0	0.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0034311	diol metabolic process(GO:0034311)
0.0	0.1	GO:0015781	pyrimidine nucleotide-sugar transport(GO:0015781)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.1	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) extrinsic apoptotic signaling pathway(GO:0097191)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0000470	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) maturation of LSU-rRNA(GO:0000470)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0045007	depurination(GO:0045007)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.0	GO:0010834	obsolete telomere maintenance via telomere shortening(GO:0010834)
0.0	0.3	GO:0006672	ceramide metabolic process(GO:0006672)
0.0	0.1	GO:0000132	establishment of mitotic spindle orientation(GO:0000132) establishment of spindle orientation(GO:0051294)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:1901797	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) negative regulation of signal transduction by p53 class mediator(GO:1901797)
0.0	0.0	GO:0022614	membrane to membrane docking(GO:0022614)
0.0	0.0	GO:0040001	establishment of mitotic spindle localization(GO:0040001)
0.0	0.0	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) metanephric mesenchymal cell differentiation(GO:0072162) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	0.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0032203	telomere formation via telomerase(GO:0032203)
0.0	0.1	GO:0015851	nucleobase transport(GO:0015851)
0.0	0.3	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.0	GO:0033688	regulation of osteoblast proliferation(GO:0033688)
0.0	0.2	GO:0061641	DNA replication-independent nucleosome assembly(GO:0006336) CENP-A containing nucleosome assembly(GO:0034080) DNA replication-independent nucleosome organization(GO:0034724) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0033160	positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0	0.1	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.0	GO:0006154	adenosine catabolic process(GO:0006154)
0.0	0.4	GO:0006626	protein targeting to mitochondrion(GO:0006626)
0.0	0.0	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.1	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.3	GO:0032480	negative regulation of type I interferon production(GO:0032480)
0.0	0.1	GO:0061001	dendritic spine morphogenesis(GO:0060997) regulation of dendritic spine morphogenesis(GO:0061001) dendritic spine organization(GO:0097061)
0.0	0.0	GO:0051176	positive regulation of sulfur metabolic process(GO:0051176)
0.0	0.0	GO:0002478	antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0	0.1	GO:0045730	respiratory burst(GO:0045730)
0.0	0.1	GO:0001510	RNA methylation(GO:0001510)
0.0	0.0	GO:0018101	protein citrullination(GO:0018101)
0.0	0.2	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	0.1	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0	0.0	GO:0048261	negative regulation of receptor-mediated endocytosis(GO:0048261)
0.0	0.0	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.0	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.2	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1	0.2	GO:0042584	chromaffin granule(GO:0042583) chromaffin granule membrane(GO:0042584)
0.1	0.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.6	GO:0001772	immunological synapse(GO:0001772)
0.0	0.1	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0	0.3	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.1	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.3	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0005900	oncostatin-M receptor complex(GO:0005900)
0.0	0.1	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.1	GO:0030895	apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0	0.2	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.0	GO:0031313	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0031045	dense core granule(GO:0031045)
0.0	0.1	GO:0005954	calcium- and calmodulin-dependent protein kinase complex(GO:0005954)
0.0	0.1	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.1	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	1.1	GO:0016605	PML body(GO:0016605)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0044298	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	0.1	GO:0070938	contractile ring(GO:0070938)
0.0	0.1	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0	0.1	GO:0010369	chromocenter(GO:0010369)
0.0	0.1	GO:0001740	Barr body(GO:0001740)
0.0	0.1	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.1	GO:0031305	integral component of mitochondrial inner membrane(GO:0031305)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.6	GO:0008287	protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0	0.1	GO:0000796	condensin complex(GO:0000796)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	0.1	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.2	GO:0016235	aggresome(GO:0016235)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.5	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.2	GO:0030530	obsolete heterogeneous nuclear ribonucleoprotein complex(GO:0030530)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0043230	extracellular organelle(GO:0043230)
0.0	0.3	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.0	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.2	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0000109	nucleotide-excision repair complex(GO:0000109)
0.0	0.0	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.0	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.1	GO:0001950	obsolete plasma membrane enriched fraction(GO:0001950)
0.0	0.0	GO:0070545	PeBoW complex(GO:0070545)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.2	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)
0.1	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0033765	steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.0	0.1	GO:0008174	mRNA methyltransferase activity(GO:0008174)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0042608	T cell receptor binding(GO:0042608)
0.0	0.2	GO:0016494	C-X-C chemokine receptor activity(GO:0016494)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.6	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0	0.3	GO:0005112	Notch binding(GO:0005112)
0.0	0.1	GO:0031628	opioid receptor binding(GO:0031628)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0042153	obsolete RPTP-like protein binding(GO:0042153)
0.0	0.2	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.2	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0000739	obsolete DNA strand annealing activity(GO:0000739)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004828	serine-tRNA ligase activity(GO:0004828)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.2	GO:0004568	chitinase activity(GO:0004568)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.1	GO:0004052	arachidonate 12-lipoxygenase activity(GO:0004052)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004775	succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.2	GO:0030371	translation repressor activity(GO:0030371)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.2	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.0	0.0	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0	0.1	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.0	0.3	GO:0001619	obsolete lysosphingolipid and lysophosphatidic acid receptor activity(GO:0001619)
0.0	0.2	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.8	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0042156	obsolete zinc-mediated transcriptional activator activity(GO:0042156)
0.0	0.3	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450) ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0004738	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.3	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0000987	RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.0	GO:0004992	platelet activating factor receptor activity(GO:0004992)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.2	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.0	0.1	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.3	GO:0043621	protein self-association(GO:0043621)
0.0	0.2	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0070402	NADPH binding(GO:0070402)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.0	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.0	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.0	0.1	GO:0051766	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) inositol trisphosphate kinase activity(GO:0051766)
0.0	0.3	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0016944	obsolete RNA polymerase II transcription elongation factor activity(GO:0016944)
0.0	0.1	GO:0050694	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.7	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.1	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.0	GO:0016972	thiol oxidase activity(GO:0016972)
0.0	0.1	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.0	GO:0043734	DNA demethylase activity(GO:0035514) DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.1	GO:0008159	obsolete positive transcription elongation factor activity(GO:0008159)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0005123	death receptor binding(GO:0005123)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.1	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0016289	CoA hydrolase activity(GO:0016289)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.1	GO:0030618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0	0.0	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.0	GO:0004167	dopachrome isomerase activity(GO:0004167)
0.0	0.0	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.2	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0	0.1	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.0	GO:0015925	galactosidase activity(GO:0015925)
0.0	0.0	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.1	GO:0004437	obsolete inositol or phosphatidylinositol phosphatase activity(GO:0004437)
0.0	0.0	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.0	GO:0005346	purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.0	GO:0033691	sialic acid binding(GO:0033691)
0.0	0.1	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.2	GO:0004177	aminopeptidase activity(GO:0004177)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.0	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.0	0.1	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.0	0.6	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	0.1	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
1.8	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.3	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.4	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.1	PID S1P S1P2 PATHWAY	S1P2 pathway
0.4	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.1	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	PID S1P S1P4 PATHWAY	S1P4 pathway
0.2	PID IL3 PATHWAY	IL3-mediated signaling events
0.2	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3	PID REELIN PATHWAY	Reelin signaling pathway
0.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.4	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.5	PID IL2 1PATHWAY	IL2-mediated signaling events
0.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.5	PID BCR 5PATHWAY	BCR signaling pathway
0.1	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.1	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.5	PID LKB1 PATHWAY	LKB1 signaling events
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	PID IL23 PATHWAY	IL23-mediated signaling events
0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	PID ALK2 PATHWAY	ALK2 signaling events
0.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.5	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
0.0	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.5	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.7	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.3	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.0	0.2	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.0	0.4	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.0	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0	0.2	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.2	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.0	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.3	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.3	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.0	0.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.0	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.1	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.0	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.7	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0	0.4	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.0	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.1	REACTOME UNFOLDED PROTEIN RESPONSE	Genes involved in Unfolded Protein Response
0.0	0.0	REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX	Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.2	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.1	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.2	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.1	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.9	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)